Year |
Citation |
Score |
2016 |
Chen X, Zheng X, Zhan M, Zhou ZY, Zhan CG, Zheng F. Metabolic Enzymes of Cocaine Metabolite Benzoylecgonine. Acs Chemical Biology. PMID 27224254 DOI: 10.1021/acschembio.6b00277 |
0.527 |
|
2016 |
Zheng X, Deng J, Zhang T, Yao J, Zheng F, Zhan CG. Potential anti-obesity effects of a long-acting cocaine hydrolase. Chemico-Biological Interactions. PMID 27163854 DOI: 10.1016/j.cbi.2016.05.010 |
0.441 |
|
2016 |
Zhang Y, Huang X, Han K, Zheng F, Zhan CG. Free energy profiles of cocaine esterase-cocaine binding process by molecular dynamics and potential of mean force simulations. Chemico-Biological Interactions. PMID 27163853 DOI: 10.1016/J.Cbi.2016.05.011 |
0.339 |
|
2016 |
Chen X, Zheng X, Zhou Z, Zhan CG, Zheng F. Effects of a cocaine hydrolase engineered from human butyrylcholinesterase on metabolic profile of cocaine in rats. Chemico-Biological Interactions. PMID 27154495 DOI: 10.1016/j.cbi.2016.05.003 |
0.517 |
|
2016 |
Zheng F, Zhan CG. Reply to Curry and Coombs: Benzoic acid is formed predominantly from the benzoyl ester hydrolysis in the presence of cocaine hydrolase. Proceedings of the National Academy of Sciences of the United States of America. PMID 27006507 DOI: 10.1073/pnas.1602720113 |
0.311 |
|
2015 |
Chen X, Xue L, Hou S, Jin Z, Zhang T, Zheng F, Zhan CG. Long-acting cocaine hydrolase for addiction therapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 26712009 DOI: 10.1073/pnas.1517713113 |
0.371 |
|
2015 |
Chen X, Huang X, Geng L, Xue L, Hou S, Zheng X, Brimijoin S, Zheng F, Zhan CG. Kinetic characterization of a cocaine hydrolase engineered from mouse butyrylcholinesterase. The Biochemical Journal. 466: 243-51. PMID 25486543 DOI: 10.1042/BJ20141266 |
0.528 |
|
2014 |
Hou S, Zhan M, Zheng X, Zhan CG, Zheng F. Kinetic characterization of human butyrylcholinesterase mutants for the hydrolysis of cocaethylene. The Biochemical Journal. 460: 447-57. PMID 24870023 DOI: 10.1042/BJ20140360 |
0.525 |
|
2012 |
Liu J, Zhan CG. Reaction Pathway and Free Energy Profile for Cocaine Hydrolase-Catalyzed Hydrolysis of (-)-Cocaine. Journal of Chemical Theory and Computation. 8: 1426-1435. PMID 23066354 DOI: 10.1021/ct200810d |
0.359 |
|
2012 |
Zheng F, Zhan CG. Modeling of pharmacokinetics of cocaine in human reveals the feasibility for development of enzyme therapies for drugs of abuse. Plos Computational Biology. 8: e1002610. PMID 22844238 DOI: 10.1371/journal.pcbi.1002610 |
0.32 |
|
2012 |
Zheng F, Zhan CG. Are pharmacokinetic approaches feasible for treatment of cocaine addiction and overdose? Future Medicinal Chemistry. 4: 125-8. PMID 22300091 DOI: 10.4155/fmc.11.171 |
0.325 |
|
2010 |
Chen Y, Zheng X, Wang J, Zhu Y, Zhan C. Reliable techniques to avoid damaging the superficial radial nerve due to percutaneous Kirschner wire fixation of the distal radius fracture through the radial styloid process. Surgical and Radiologic Anatomy : Sra. 32: 711-7. PMID 20306262 DOI: 10.1007/s00276-010-0652-2 |
0.34 |
|
2006 |
Gao D, Zhan CG. Modeling evolution of hydrogen bonding and stabilization of transition states in the process of cocaine hydrolysis catalysed by human butyrylcholinesterase Proteins: Structure, Function and Genetics. 62: 99-110. PMID 16288482 DOI: 10.1002/prot.20713 |
0.31 |
|
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