Robby Weimer - Publications

Affiliations: 
Genentech, San Francisco, CA, United States 

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Xi H, Katschke KJ, Li Y, Truong T, Lee WP, Diehl L, Rangell L, Tao J, Arceo R, Eastham-Anderson J, Hackney JA, Iglesias A, Cote-Sierra J, Elstrott J, Weimer RM, et al. IL-33 amplifies an innate immune response in the degenerating retina. The Journal of Experimental Medicine. PMID 26755704 DOI: 10.1084/jem.20150894  0.8
2015 Zuchero YJ, Chen X, Bien-Ly N, Bumbaca D, Tong RK, Gao X, Zhang S, Hoyte K, Luk W, Huntley MA, Phu L, Tan C, Kallop D, Weimer RM, Lu Y, et al. Discovery of Novel Blood-Brain Barrier Targets to Enhance Brain Uptake of Therapeutic Antibodies. Neuron. PMID 26687840 DOI: 10.1016/j.neuron.2015.11.024  0.8
2014 Chen Y, Wang Y, Ertürk A, Kallop D, Jiang Z, Weimer RM, Kaminker J, Sheng M. Activity-induced Nr4a1 regulates spine density and distribution pattern of excitatory synapses in pyramidal neurons. Neuron. 83: 431-43. PMID 24976215 DOI: 10.1016/j.neuron.2014.05.027  0.8
2014 Hanson JE, Meilandt WJ, Gogineni A, Reynen P, Herrington J, Weimer RM, Scearce-Levie K, Zhou Q. Chronic GluN2B antagonism disrupts behavior in wild-type mice without protecting against synapse loss or memory impairment in Alzheimer's disease mouse models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8277-88. PMID 24920631 DOI: 10.1523/JNEUROSCI.5106-13.2014  0.8
2014 Olsen O, Kallop DY, McLaughlin T, Huntwork-Rodriguez S, Wu Z, Duggan CD, Simon DJ, Lu Y, Easley-Neal C, Takeda K, Hass PE, Jaworski A, O'Leary DD, Weimer RM, Tessier-Lavigne M. Genetic analysis reveals that amyloid precursor protein and death receptor 6 function in the same pathway to control axonal pruning independent of β-secretase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6438-47. PMID 24806670 DOI: 10.1523/JNEUROSCI.3522-13.2014  0.8
2014 Kallop DY, Meilandt WJ, Gogineni A, Easley-Neal C, Wu T, Jubb AM, Yaylaoglu M, Shamloo M, Tessier-Lavigne M, Scearce-Levie K, Weimer RM. A death receptor 6-amyloid precursor protein pathway regulates synapse density in the mature CNS but does not contribute to Alzheimer's disease-related pathophysiology in murine models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6425-37. PMID 24806669 DOI: 10.1523/JNEUROSCI.4963-13.2014  0.8
2014 Bien-Ly N, Yu YJ, Bumbaca D, Elstrott J, Boswell CA, Zhang Y, Luk W, Lu Y, Dennis MS, Weimer RM, Chung I, Watts RJ. Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants. The Journal of Experimental Medicine. 211: 233-44. PMID 24470444 DOI: 10.1084/jem.20131660  0.8
2014 Hazen M, Bhakta S, Vij R, Randle S, Kallop D, Chiang V, Hötzel I, Jaiswal BS, Ervin KE, Li B, Weimer RM, Polakis P, Scheller RH, Junutula JR, Hongo JA. An improved and robust DNA immunization method to develop antibodies against extracellular loops of multi-transmembrane proteins. Mabs. 6: 95-107. PMID 24121517 DOI: 10.4161/mabs.26761  0.8
2014 Weimer R, Richmond J. Munc13 and Associated Molecules Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.04674-2  0.8
2013 Yang J, Weimer RM, Kallop D, Olsen O, Wu Z, Renier N, Uryu K, Tessier-Lavigne M. Regulation of axon degeneration after injury and in development by the endogenous calpain inhibitor calpastatin. Neuron. 80: 1175-89. PMID 24210906 DOI: 10.1016/j.neuron.2013.08.034  0.8
2013 Pozniak CD, Sengupta Ghosh A, Gogineni A, Hanson JE, Lee SH, Larson JL, Solanoy H, Bustos D, Li H, Ngu H, Jubb AM, Ayalon G, Wu J, Scearce-Levie K, Zhou Q, ... Weimer RM, et al. Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration. The Journal of Experimental Medicine. 210: 2553-67. PMID 24166713 DOI: 10.1084/jem.20122832  0.8
2013 Gogineni A, Caunt M, Crow A, Lee CV, Fuh G, van Bruggen N, Ye W, Weimer RM. Inhibition of VEGF-C modulates distal lymphatic remodeling and secondary metastasis. Plos One. 8: e68755. PMID 23874750 DOI: 10.1371/journal.pone.0068755  0.8
2012 Simon DJ, Weimer RM, McLaughlin T, Kallop D, Stanger K, Yang J, O'Leary DD, Hannoush RN, Tessier-Lavigne M. A caspase cascade regulating developmental axon degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17540-53. PMID 23223278 DOI: 10.1523/JNEUROSCI.3012-12.2012  0.8
2012 Chen M, Maloney JA, Kallop DY, Atwal JK, Tam SJ, Baer K, Kissel H, Kaminker JS, Lewcock JW, Weimer RM, Watts RJ. Spatially coordinated kinase signaling regulates local axon degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 13439-53. PMID 23015435 DOI: 10.1523/JNEUROSCI.2039-12.2012  0.8
2012 Wilson NS, Yang A, Yang B, Couto S, Stern H, Gogineni A, Pitti R, Marsters S, Weimer RM, Singh M, Ashkenazi A. Proapoptotic activation of death receptor 5 on tumor endothelial cells disrupts the vasculature and reduces tumor growth. Cancer Cell. 22: 80-90. PMID 22789540 DOI: 10.1016/j.ccr.2012.05.014  0.8
2012 Adolfsson O, Pihlgren M, Toni N, Varisco Y, Buccarello AL, Antoniello K, Lohmann S, Piorkowska K, Gafner V, Atwal JK, Maloney J, Chen M, Gogineni A, Weimer RM, Mortensen DL, et al. An effector-reduced anti-β-amyloid (Aβ) antibody with unique aβ binding properties promotes neuroprotection and glial engulfment of Aβ. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9677-89. PMID 22787053 DOI: 10.1523/JNEUROSCI.4742-11.2012  0.8
2012 Weimer RM, Hill TC, Hamilton AM, Zito K. Imaging synaptic protein dynamics using photoactivatable green fluorescent protein. Cold Spring Harbor Protocols. 2012: 771-7. PMID 22753605 DOI: 10.1101/pdb.prot070029  0.8
2012 Kozlowski C, Weimer RM. An automated method to quantify microglia morphology and application to monitor activation state longitudinally in vivo. Plos One. 7: e31814. PMID 22457705 DOI: 10.1371/journal.pone.0031814  0.8
2012 Gleason EJ, Hartley PD, Henderson M, Hill-Harfe KL, Price PW, Weimer RM, Kroft TL, Zhu GD, Cordovado S, L'Hernault SW. Developmental genetics of secretory vesicle acidification during Caenorhabditis elegans spermatogenesis. Genetics. 191: 477-91. PMID 22446317 DOI: 10.1534/genetics.112.139618  0.8
2012 Ernstrom GG, Weimer R, Pawar DR, Watanabe S, Hobson RJ, Greenstein D, Jorgensen EM. V-ATPase V1 sector is required for corpse clearance and neurotransmission in Caenorhabditis elegans. Genetics. 191: 461-75. PMID 22426883 DOI: 10.1534/genetics.112.139667  0.8
2012 Tam SJ, Richmond DL, Kaminker JS, Modrusan Z, Martin-McNulty B, Cao TC, Weimer RM, Carano RA, van Bruggen N, Watts RJ. Death receptors DR6 and TROY regulate brain vascular development. Developmental Cell. 22: 403-17. PMID 22340501 DOI: 10.1016/j.devcel.2011.11.018  0.8
2011 Goergen CJ, Azuma J, Barr KN, Magdefessel L, Kallop DY, Gogineni A, Grewall A, Weimer RM, Connolly AJ, Dalman RL, Taylor CA, Tsao PS, Greve JM. Influences of aortic motion and curvature on vessel expansion in murine experimental aneurysms. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 270-9. PMID 21071686 DOI: 10.1161/ATVBAHA.110.216481  0.8
2010 Kowanetz M, Wu X, Lee J, Tan M, Hagenbeek T, Qu X, Yu L, Ross J, Korsisaari N, Cao T, Bou-Reslan H, Kallop D, Weimer R, Ludlam MJ, Kaminker JS, et al. Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes. Proceedings of the National Academy of Sciences of the United States of America. 107: 21248-55. PMID 21081700 DOI: 10.1073/pnas.1015855107  0.8
2010 Ye X, Li Y, Stawicki S, Couto S, Eastham-Anderson J, Kallop D, Weimer R, Wu Y, Pei L. An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies. Oncogene. 29: 5254-64. PMID 20603615 DOI: 10.1038/onc.2010.268  0.8
2010 Weimer R, Richmond J. Munc13 and Associated Molecules Encyclopedia of Neuroscience. 1125-1130. DOI: 10.1016/B978-008045046-9.01366-8  0.8
2009 Blum G, Weimer RM, Edgington LE, Adams W, Bogyo M. Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity. Plos One. 4: e6374. PMID 19636372 DOI: 10.1371/journal.pone.0006374  0.8
2009 Sato K, Ernstrom GG, Watanabe S, Weimer RM, Chen CH, Sato M, Siddiqui A, Jorgensen EM, Grant BD. Differential requirements for clathrin in receptor-mediated endocytosis and maintenance of synaptic vesicle pools. Proceedings of the National Academy of Sciences of the United States of America. 106: 1139-44. PMID 19151157 DOI: 10.1073/pnas.0809541106  0.8
2009 Goergen CJ, Kallop DY, Taylor CA, Weimer RM, Greve JM. Protease expression colocalizes to regions of abdominal aortic expansion and stiffening in a murine aneurysm model Proceedings of the Asme Summer Bioengineering Conference, Sbc2008. 175-176.  0.8
2006 Gray NW, Weimer RM, Bureau I, Svoboda K. Rapid redistribution of synaptic PSD-95 in the neocortex in vivo. Plos Biology. 4: e370. PMID 17090216 DOI: 10.1371/journal.pbio.0040370  0.8
2006 Weimer RM. Preservation of C. elegans tissue via high-pressure freezing and freeze-substitution for ultrastructural analysis and immunocytochemistry. Methods in Molecular Biology (Clifton, N.J.). 351: 203-21. PMID 16988436 DOI: 10.1385/1-59745-151-7:203  0.8
2006 Gracheva EO, Burdina AO, Holgado AM, Berthelot-Grosjean M, Ackley BD, Hadwiger G, Nonet ML, Weimer RM, Richmond JE. Tomosyn inhibits synaptic vesicle priming in Caenorhabditis elegans. Plos Biology. 4: e261. PMID 16895441 DOI: 10.1371/journal.pbio.0040261  0.8
2006 Weimer RM, Gracheva EO, Meyrignac O, Miller KG, Richmond JE, Bessereau JL. UNC-13 and UNC-10/rim localize synaptic vesicles to specific membrane domains. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8040-7. PMID 16885217 DOI: 10.1523/JNEUROSCI.2350-06.2006  0.8
2006 Abraham C, Hutter H, Palfreyman MT, Spatkowski G, Weimer RM, Windoffer R, Jorgensen EM, Leube RE. Synaptic tetraspan vesicle membrane proteins are conserved but not needed for synaptogenesis and neuronal function in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 103: 8227-32. PMID 16698939 DOI: 10.1073/pnas.0509400103  0.8
2005 Portera-Cailliau C, Weimer RM, De Paola V, Caroni P, Svoboda K. Diverse modes of axon elaboration in the developing neocortex. Plos Biology. 3: e272. PMID 16026180 DOI: 10.1371/journal.pbio.0030272  0.8
2005 Yeh E, Kawano T, Weimer RM, Bessereau JL, Zhen M. Identification of genes involved in synaptogenesis using a fluorescent active zone marker in Caenorhabditis elegans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3833-41. PMID 15829635 DOI: 10.1523/JNEUROSCI.4978-04.2005  0.8
2005 Weimer RM, Richmond JE. Synaptic vesicle docking: a putative role for the Munc18/Sec1 protein family. Current Topics in Developmental Biology. 65: 83-113. PMID 15642380 DOI: 10.1016/S0070-2153(04)65003-4  0.8
2004 Rostaing P, Weimer RM, Jorgensen EM, Triller A, Bessereau JL. Preservation of immunoreactivity and fine structure of adult C. elegans tissues using high-pressure freezing. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 52: 1-12. PMID 14688212  0.8
2003 Weimer RM, Richmond JE, Davis WS, Hadwiger G, Nonet ML, Jorgensen EM. Defects in synaptic vesicle docking in unc-18 mutants. Nature Neuroscience. 6: 1023-30. PMID 12973353 DOI: 10.1038/nn1118  0.8
2003 Weimer RM, Jorgensen EM. Controversies in synaptic vesicle exocytosis. Journal of Cell Science. 116: 3661-6. PMID 12917353 DOI: 10.1242/jcs.00687  0.8
2003 Bosher JM, Hahn BS, Legouis R, Sookhareea S, Weimer RM, Gansmuller A, Chisholm AD, Rose AM, Bessereau JL, Labouesse M. The Caenorhabditis elegans vab-10 spectraplakin isoforms protect the epidermis against internal and external forces. The Journal of Cell Biology. 161: 757-68. PMID 12756232 DOI: 10.1083/jcb.200302151  0.8
2001 Koushika SP, Richmond JE, Hadwiger G, Weimer RM, Jorgensen EM, Nonet ML. A post-docking role for active zone protein Rim. Nature Neuroscience. 4: 997-1005. PMID 11559854 DOI: 10.1038/nn732  0.8
2001 Richmond JE, Weimer RM, Jorgensen EM. An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming. Nature. 412: 338-41. PMID 11460165 DOI: 10.1038/35085583  0.8
1998 Weimer RM, Creighton Cx, Stassinopoulos A, Youderian P, Hartzell PL. A chaperone in the HSP70 family controls production of extracellular fibrils in Myxococcus xanthus. Journal of Bacteriology. 180: 5357-68. PMID 9765567  0.8
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