Brian Harfe - Publications

Affiliations: 
Molecular Genetics and Microbiology University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Evolution and Development Biology, Genetics

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Zhu J, Patel R, Trofka A, Harfe BD, Mackem S. Sonic hedgehog is not a limb morphogen but acts as a trigger to specify all digits in mice. Developmental Cell. PMID 35977544 DOI: 10.1016/j.devcel.2022.07.016  0.309
2022 Reibring CG, El Shahawy M, Hallberg K, Harfe BD, Linde A, Gritli-Linde A. Loss of BMP2 and BMP4 Signaling in the Dental Epithelium Causes Defective Enamel Maturation and Aberrant Development of Ameloblasts. International Journal of Molecular Sciences. 23. PMID 35682776 DOI: 10.3390/ijms23116095  0.339
2019 El Shahawy M, Reibring CG, Hallberg K, Neben CL, Marangoni P, Harfe BD, Klein OD, Linde A, Gritli-Linde A. Sonic Hedgehog Signaling Is Required for Cyp26 Expression during Embryonic Development. International Journal of Molecular Sciences. 20. PMID 31072004 DOI: 10.3390/ijms20092275  0.323
2019 Henriques T, Agostinelli E, Hernandez-Clavijo A, Maurya DK, Rock JR, Harfe BD, Menini A, Pifferi S. TMEM16A calcium-activated chloride currents in supporting cells of the mouse olfactory epithelium. The Journal of General Physiology. PMID 31048412 DOI: 10.1085/Jgp.201812310  0.63
2017 Peck SH, McKee KK, Tobias JW, Malhotra NR, Harfe BD, Smith LJ. Whole Transcriptome Analysis of Notochord-Derived Cells during Embryonic Formation of the Nucleus Pulposus. Scientific Reports. 7: 10504. PMID 28874804 DOI: 10.1038/S41598-017-10692-5  0.319
2016 Kaltcheva MM, Anderson MJ, Harfe BD, Lewandoski M. BMPs are direct triggers of interdigital programmed cell death. Developmental Biology. 411: 266-76. PMID 26826495 DOI: 10.1016/J.Ydbio.2015.12.016  0.324
2015 Maurya DK, Henriques T, Marini M, Pedemonte N, Galietta LJ, Rock JR, Harfe BD, Menini A. Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice. Plos One. 10: e0129171. PMID 26067252 DOI: 10.1371/Journal.Pone.0129171  0.655
2015 Maurya DK, Henriques T, Marini M, Pedemonte N, Galietta LJV, Rock JR, Harfe BD, Menini AM. Development of the olfactory epithelium and Nasal Glands in TMEM16A-/-and TMEM16A+/ +Mice Plos One. 10. DOI: 10.1371/journal.pone.0129171  0.604
2014 Singh RD, Gibbons SJ, Saravanaperumal SA, Du P, Hennig GW, Eisenman ST, Mazzone A, Hayashi Y, Cao C, Stoltz GJ, Ordog T, Rock JR, Harfe BD, Szurszewski JH, Farrugia G. Ano1, a Ca2+-activated Cl- channel, coordinates contractility in mouse intestine by Ca2+ transient coordination between interstitial cells of Cajal. The Journal of Physiology. 592: 4051-68. PMID 25063822 DOI: 10.1113/Jphysiol.2014.277152  0.615
2014 Norrie JL, Lewandowski JP, Bouldin CM, Amarnath S, Li Q, Vokes MS, Ehrlich LI, Harfe BD, Vokes SA. Dynamics of BMP signaling in limb bud mesenchyme and polydactyly. Developmental Biology. 393: 270-81. PMID 25034710 DOI: 10.1016/J.Ydbio.2014.07.003  0.78
2014 deCarvalho TN, Subedi A, Rock J, Harfe BD, Thisse C, Thisse B, Halpern ME, Hong E. Neurotransmitter map of the asymmetric dorsal habenular nuclei of zebrafish. Genesis (New York, N.Y. : 2000). 52: 636-55. PMID 24753112 DOI: 10.1002/Dvg.22785  0.635
2013 Anderegg A, Lin HP, Chen JA, Caronia-Brown G, Cherepanova N, Yun B, Joksimovic M, Rock J, Harfe BD, Johnson R, Awatramani R. An Lmx1b-miR135a2 regulatory circuit modulates Wnt1/Wnt signaling and determines the size of the midbrain dopaminergic progenitor pool. Plos Genetics. 9: e1003973. PMID 24348261 DOI: 10.1371/Journal.Pgen.1003973  0.656
2013 Maier JA, Lo Y, Harfe BD. Foxa1 and Foxa2 are required for formation of the intervertebral discs. Plos One. 8: e55528. PMID 23383217 DOI: 10.1371/journal.pone.0055528  0.743
2012 Hu JK, McGlinn E, Harfe BD, Kardon G, Tabin CJ. Autonomous and nonautonomous roles of Hedgehog signaling in regulating limb muscle formation. Genes & Development. 26: 2088-102. PMID 22987639 DOI: 10.1101/Gad.187385.112  0.309
2012 Choi KS, Lee C, Harfe BD. Sonic hedgehog in the notochord is sufficient for patterning of the intervertebral discs. Mechanisms of Development. 129: 255-62. PMID 22841806 DOI: 10.1016/J.Mod.2012.07.003  0.742
2012 Choi KS, Lee C, Maatouk DM, Harfe BD. Bmp2, Bmp4 and Bmp7 are co-required in the mouse AER for normal digit patterning but not limb outgrowth. Plos One. 7: e37826. PMID 22662233 DOI: 10.1371/journal.pone.0037826  0.739
2012 Duvvuri U, Shiwarski DJ, Xiao D, Bertrand C, Huang X, Edinger RS, Rock JR, Harfe BD, Henson BJ, Kunzelmann K, Schreiber R, Seethala RS, Egloff AM, Chen X, Lui VW, et al. TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression. Cancer Research. 72: 3270-81. PMID 22564524 DOI: 10.1158/0008-5472.Can-12-0475-T  0.615
2012 Bruggeman BJ, Maier JA, Mohiuddin YS, Powers R, Lo Y, Guimarães-Camboa N, Evans SM, Harfe BD. Avian intervertebral disc arises from rostral sclerotome and lacks a nucleus pulposus: implications for evolution of the vertebrate disc. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 241: 675-83. PMID 22354863 DOI: 10.1002/dvdy.23750  0.729
2012 Dixon RE, Hennig GW, Baker SA, Britton FC, Harfe BD, Rock JR, Sanders KM, Ward SM. Electrical slow waves in the mouse oviduct are dependent upon a calcium activated chloride conductance encoded by Tmem16a. Biology of Reproduction. 86: 1-7. PMID 21976594 DOI: 10.1095/Biolreprod.111.095554  0.599
2011 Stanich JE, Gibbons SJ, Eisenman ST, Bardsley MR, Rock JR, Harfe BD, Ordog T, Farrugia G. Ano1 as a regulator of proliferation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 301: G1044-51. PMID 21940901 DOI: 10.1152/Ajpgi.00196.2011  0.646
2011 Choi KS, Harfe BD. Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the intervertebral discs. Proceedings of the National Academy of Sciences of the United States of America. 108: 9484-9. PMID 21606373 DOI: 10.1016/J.Ydbio.2011.05.593  0.756
2011 Harfe BD. Keeping up with the zone of polarizing activity: New roles for an old signaling center. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 915-9. PMID 21360795 DOI: 10.1002/dvdy.22597  0.313
2011 Maier JA, Harfe BD. Nuclei pulposi formation from the embryonic notochord occurs normally in GDF-5-deficient mice. Spine. 36: E1555-61. PMID 21278629 DOI: 10.1097/BRS.0b013e318210eec4  0.707
2011 Smith LJ, Nerurkar NL, Choi KS, Harfe BD, Elliott DM. Degeneration and regeneration of the intervertebral disc: lessons from development. Disease Models & Mechanisms. 4: 31-41. PMID 21123625 DOI: 10.1242/Dmm.006403  0.701
2011 Maier J, Lo YT, Harfe B. Foxa1 and Foxa2 in the intervertebral disk Developmental Biology. 356: 234-235. DOI: 10.1016/J.Ydbio.2011.05.401  0.671
2010 Bouldin CM, Gritli-Linde A, Ahn S, Harfe BD. Shh pathway activation is present and required within the vertebrate limb bud apical ectodermal ridge for normal autopod patterning. Proceedings of the National Academy of Sciences of the United States of America. 107: 5489-94. PMID 20212115 DOI: 10.1073/Pnas.0912818107  0.782
2010 Romanenko VG, Catalán MA, Brown DA, Putzier I, Hartzell HC, Marmorstein AD, Gonzalez-Begne M, Rock JR, Harfe BD, Melvin JE. Tmem16A encodes the Ca2+-activated Cl- channel in mouse submandibular salivary gland acinar cells. The Journal of Biological Chemistry. 285: 12990-3001. PMID 20177062 DOI: 10.1074/Jbc.M109.068544  0.616
2010 Stanich JE, Gibbons SJ, Rock JR, Harfe BD, Ordog T, Farrugia G. S2060 Ano1 Plays a Role in the Proliferation of ICC Gastroenterology. 138: S-311. DOI: 10.1016/S0016-5085(10)61432-1  0.586
2010 Choi K, Harfe BD. Role of hedgehog signaling in intervertebral disc development Developmental Biology. 344: 485. DOI: 10.1016/J.Ydbio.2010.05.288  0.718
2009 Huang F, Rock JR, Harfe BD, Cheng T, Huang X, Jan YN, Jan LY. Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proceedings of the National Academy of Sciences of the United States of America. 106: 21413-8. PMID 19965375 DOI: 10.1073/Pnas.0911935106  0.638
2009 Seifert AW, Bouldin CM, Choi KS, Harfe BD, Cohn MJ. Multiphasic and tissue-specific roles of sonic hedgehog in cloacal septation and external genitalia development. Development (Cambridge, England). 136: 3949-57. PMID 19906862 DOI: 10.1242/Dev.042291  0.767
2009 Hwang SJ, Blair PJ, Britton FC, O'Driscoll KE, Hennig G, Bayguinov YR, Rock JR, Harfe BD, Sanders KM, Ward SM. Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles. The Journal of Physiology. 587: 4887-904. PMID 19687122 DOI: 10.1113/Jphysiol.2009.176198  0.625
2009 Ousingsawat J, Martins JR, Schreiber R, Rock JR, Harfe BD, Kunzelmann K. Loss of TMEM16A causes a defect in epithelial Ca2+-dependent chloride transport. The Journal of Biological Chemistry. 284: 28698-703. PMID 19679661 DOI: 10.1074/jbc.M109.012120  0.606
2009 Almaça J, Tian Y, Aldehni F, Ousingsawat J, Kongsuphol P, Rock JR, Harfe BD, Schreiber R, Kunzelmann K. TMEM16 proteins produce volume-regulated chloride currents that are reduced in mice lacking TMEM16A. The Journal of Biological Chemistry. 284: 28571-8. PMID 19654323 DOI: 10.1074/jbc.M109.010074  0.629
2009 Bouldin CM, Harfe BD. Aberrant FGF signaling, independent of ectopic hedgehog signaling, initiates preaxial polydactyly in Dorking chickens. Developmental Biology. 334: 133-41. PMID 19616534 DOI: 10.1016/J.Ydbio.2009.07.009  0.794
2009 Rock JR, O'Neal WK, Gabriel SE, Randell SH, Harfe BD, Boucher RC, Grubb BR. Transmembrane protein 16A (TMEM16A) is a Ca2+ -regulated Cl- secretory channel in mouse airways Journal of Biological Chemistry. 284: 14875-14880. PMID 19363029 DOI: 10.1074/Jbc.C109.000869  0.635
2009 Maatouk DM, Choi KS, Bouldin CM, Harfe BD. In the limb AER Bmp2 and Bmp4 are required for dorsal-ventral patterning and interdigital cell death but not limb outgrowth. Developmental Biology. 327: 516-23. PMID 19210962 DOI: 10.1016/J.Ydbio.2009.01.004  0.782
2009 Gritli-Linde A, Vaziri Sani F, Rock JR, Hallberg K, Iribarne D, Harfe BD, Linde A. Expression patterns of the Tmem16 gene family during cephalic development in the mouse. Gene Expression Patterns : Gep. 9: 178-91. PMID 19059364 DOI: 10.1016/J.Gep.2008.11.002  0.651
2009 Bouldin CM, Harfe BD. Sonic hedgehog signaling in the apical ectodermal ridge is essential for proper patterning of the vertebrate limb Developmental Biology. 331: 529. DOI: 10.1016/J.Ydbio.2009.05.531  0.772
2009 Choi K, Harfe BD. Cell-autonomous role of hedgehog signaling in notochord and intervertebral disc development Developmental Biology. 331: 499. DOI: 10.1016/J.Ydbio.2009.05.425  0.731
2008 Choi KS, Cohn MJ, Harfe BD. Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 3953-8. PMID 19035356 DOI: 10.1002/Dvdy.21805  0.72
2008 Rock JR, Harfe BD. Expression of TMEM16 paralogs during murine embryogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 2566-74. PMID 18729231 DOI: 10.1002/Dvdy.21676  0.634
2008 Rock JR, Futtner CR, Harfe BD. The transmembrane protein TMEM16A is required for normal development of the murine trachea. Developmental Biology. 321: 141-9. PMID 18585372 DOI: 10.1016/J.Ydbio.2008.06.009  0.663
2008 Seifert AW, Harfe BD, Cohn MJ. Cell lineage analysis demonstrates an endodermal origin of the distal urethra and perineum. Developmental Biology. 318: 143-52. PMID 18439576 DOI: 10.1016/J.Ydbio.2008.03.017  0.312
2007 Rock JR, Lopez MC, Baker HV, Harfe BD. Identification of genes expressed in the mouse limb using a novel ZPA microarray approach. Gene Expression Patterns : Gep. 8: 19-26. PMID 17911046 DOI: 10.1016/J.Modgep.2007.08.004  0.668
2007 Nissim S, Allard P, Bandyopadhyay A, Harfe BD, Tabin CJ. Characterization of a novel ectodermal signaling center regulating Tbx2 and Shh in the vertebrate limb. Developmental Biology. 304: 9-21. PMID 17300775 DOI: 10.1016/J.Ydbio.2006.12.010  0.302
2007 Bouldin CM, Harfe BD. Molecular characterization of a nonsyndromic polydactylous chicken Developmental Biology. 306: 359. DOI: 10.1016/J.Ydbio.2007.03.243  0.726
2007 Choi K, Maatouk DM, Harfe BD. Genetic analysis of BMP2 and BMP4 in the limb apical ectoderm ridge Developmental Biology. 306: 358. DOI: 10.1016/J.Ydbio.2007.03.240  0.681
2007 Seifert AW, Harfe B, Cohn MJ. Multiphasic role of Shh during external genital development and cloacal septation Developmental Biology. 306: 313. DOI: 10.1016/J.Ydbio.2007.03.113  0.339
2006 Bandyopadhyay A, Tsuji K, Cox K, Harfe BD, Rosen V, Tabin CJ. Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis. Plos Genetics. 2: e216. PMID 17194222 DOI: 10.1371/Journal.Pgen.0020216  0.334
2006 Seifert AW, Harfe B, Cohn MJ. Origin of the penile urethra and the proximodistal fate of the urethral epithelium Developmental Biology. 295: 459. DOI: 10.1016/J.Ydbio.2006.04.413  0.337
2006 Harfe BD, Rock JR. Characterization of a novel gene expressed exclusively in the zone of polarizing activity in the vertebrate limb Developmental Biology. 295: 447. DOI: 10.1016/J.Ydbio.2006.04.378  0.619
2006 Bouldin CM, Cohn MJ, Harfe BD. Molecular analysis of a polydactylous chicken Developmental Biology. 295: 388. DOI: 10.1016/J.Ydbio.2006.04.191  0.724
2005 Verheyden JM, Lewandoski M, Deng C, Harfe BD, Sun X. Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning. Development (Cambridge, England). 132: 4235-45. PMID 16120640 DOI: 10.1242/Dev.02001  0.34
2005 Tian H, Jeong J, Harfe BD, Tabin CJ, McMahon AP. Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand. Development (Cambridge, England). 132: 133-42. PMID 15576405 DOI: 10.1242/Dev.01563  0.324
2004 Scherz PJ, Harfe BD, McMahon AP, Tabin CJ. The limb bud Shh-Fgf feedback loop is terminated by expansion of former ZPA cells. Science (New York, N.Y.). 305: 396-9. PMID 15256670 DOI: 10.1126/Science.1096966  0.335
2003 Anakwe K, Robson L, Hadley J, Buxton P, Church V, Allen S, Hartmann C, Harfe B, Nohno T, Brown AM, Evans DJ, Francis-West P. Wnt signalling regulates myogenic differentiation in the developing avian wing. Development (Cambridge, England). 130: 3503-14. PMID 12810597 DOI: 10.1242/Dev.00538  0.456
1998 Harfe BD, Vaz Gomes A, Kenyon C, Liu J, Krause M, Fire A. Analysis of a Caenorhabditis elegans Twist homolog identifies conserved and divergent aspects of mesodermal patterning. Genes & Development. 12: 2623-35. PMID 9716413 DOI: 10.1101/Gad.12.16.2623  0.304
1993 Bai M, Harfe B, Freimuth P. Mutations that alter an Arg-Gly-Asp (RGD) sequence in the adenovirus type 2 penton base protein abolish its cell-rounding activity and delay virus reproduction in flat cells Journal of Virology. 67: 5198-5205. PMID 8350395 DOI: 10.1128/Jvi.67.9.5198-5205.1993  0.301
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