| Year |
Citation |
Score |
| 2023 |
Aseem SO, Hylemon PB, Zhou H. Bile Acids and Biliary Fibrosis. Cells. 12. PMID 36899928 DOI: 10.3390/cells12050792 |
0.304 |
|
| 2021 |
Hylemon PB, Su L, Zheng PC, Bajaj JS, Zhou H. Bile Acids, Gut Microbiome and the Road to Fatty Liver Disease. Comprehensive Physiology. 12: 2719-2730. PMID 34964117 DOI: 10.1002/cphy.c210024 |
0.301 |
|
| 2021 |
Wang Y, Tai YL, Zhao D, Zhang Y, Yan J, Kakiyama G, Wang X, Gurley EC, Liu J, Liu J, Liu J, Lai G, Hylemon PB, Pandak WM, Chen W, et al. Berberine Prevents Disease Progression of Nonalcoholic Steatohepatitis through Modulating Multiple Pathways. Cells. 10. PMID 33494295 DOI: 10.3390/cells10020210 |
0.31 |
|
| 2020 |
Wang Y, Chen L, Pandak WM, Heuman D, Hylemon PB, Ren S. High Glucose Induces Lipid Accumulation via 25-Hydroxycholesterol DNA-CpG Methylation. Iscience. 23: 101102. PMID 32408171 DOI: 10.1016/J.Isci.2020.101102 |
0.345 |
|
| 2020 |
Wang Y, Zhou X, Zhao D, Wang X, Gurley EC, Liu R, Li X, Hylemon PB, Chen W, Zhou H. Berberine inhibits free fatty acid and LPS-induced inflammation via modulating ER stress response in macrophages and hepatocytes. Plos One. 15: e0232630. PMID 32357187 DOI: 10.1371/Journal.Pone.0232630 |
0.36 |
|
| 2020 |
Li X, Liu R, Wang Y, Zhu W, Zhao D, Wang X, Yang H, Gurley EC, Chen W, Hylemon PB, Zhou H. Cholangiocyte-Derived Exosomal lncRNA H19 Promotes Macrophage Activation and Hepatic Inflammation under Cholestatic Conditions. Cells. 9. PMID 31940841 DOI: 10.3390/Cells9010190 |
0.334 |
|
| 2020 |
Wang Y, Xiang D, Chen W, Zhao D, Gurley E, Wang X, Pu G, Tai Y, Zhang Y, Chen Z, Wu J, Yan J, Hylemon PB, Zhou H. Berberine attenuates cholestatic liver and bile duct injury in Mdr2
−/−
mice by maintaining bile acid homeostasis The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04758 |
0.331 |
|
| 2020 |
Zhang Y, Kang D, Zhao D, Yan J, Ghosh S, Sikaroodi M, Tai Y, Wang Y, Gurley E, Liu R, Gillevet PM, Hylemon P, Zhou H, Bajaj JS. Su1592 NEURO AND HEPATIC INFLAMMATION AND STEATOSIS ARE MODULATED BY GUT MICROBIAL CHANGES AFTER ISOLATED HEPATIC VAGOTOMY AND ANTIBIOTICS IN CIRRHOSIS Gastroenterology. 158: S-1349-S-1350. DOI: 10.1016/S0016-5085(20)34045-2 |
0.321 |
|
| 2020 |
Wang Y, Ge P, Tai Y, Wu J, Zhang Y, Zhao D, Wang X, Gurley E, Hylemon P, Chen W, Zhou H. 321 HEPATIC HUR PROTECTS AGAINST DIET-INDUCED LIPID METABOLISM DISORDER Gastroenterology. 158: S-1266. DOI: 10.1016/S0016-5085(20)33823-3 |
0.319 |
|
| 2020 |
Zhang Y, Wang R, Wang Y, Tai Y, Ge P, Wu J, Yang W, Zhao D, Wang X, Gurley E, Hylemon P, Wang W, Zhou H. 215 BILE ACID-INDUCED UPREGULATION OF MICRORNA 155 PROMOTES CHOLESTATIC LIVER INJURY VIA TARGETING THE INSIG2/SREBP1 PATHWAY IN MDR2-/- MICE. Gastroenterology. 158: S-1262. DOI: 10.1016/S0016-5085(20)33810-5 |
0.357 |
|
| 2019 |
Liu R, Kang JD, Sartor RB, Sikaroodi M, Fagan A, Gavis EA, Zhou H, Hylemon PB, Herzog JW, Li X, Lippman RH, Maeso JG, Wade JB, Ghosh S, Gurley E, et al. Neuroinflammation in Murine Cirrhosis is Dependent on the Gut Microbiome and is Attenuated by Fecal Transplant. Hepatology (Baltimore, Md.). PMID 31220352 DOI: 10.1002/Hep.30827 |
0.345 |
|
| 2019 |
Xiao Y, Liu R, Li X, Gurley EC, Hylemon PB, Lu Y, Zhou H, Cai W. Long non-coding RNA H19 contributes to cholangiocyte proliferation and cholestatic liver fibrosis in biliary atresia. Hepatology (Baltimore, Md.). PMID 31063660 DOI: 10.1002/Hep.30698 |
0.339 |
|
| 2019 |
Kwong EK, Liu R, Zhao D, Li X, Zhu W, Wang X, Gurley EC, Lai G, Liu J, Hylemon PB, Zhou H. The role of sphingosine kinase 2 in alcoholic liver disease. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. PMID 31003959 DOI: 10.1016/J.Dld.2019.03.020 |
0.376 |
|
| 2019 |
Liu R, Li X, Zhu W, Wang Y, Zhao D, Wang X, Gurley EC, Liang G, Chen W, Lai G, Pandak WM, Lippman HR, Bajaj JS, Hylemon PB, Zhou H. Cholangiocyte-derived exosomal LncRNA H19 promotes hepatic stellate cell activation and cholestatic liver fibrosis. Hepatology (Baltimore, Md.). PMID 30985008 DOI: 10.1002/Hep.30662 |
0.316 |
|
| 2019 |
Gaidos J, Kang JD, Kakiyama G, Pandak WM, Hylemon PB. 747 Pilot Study of Gut Dysbiosis and Bile Acid Dysmetabolism in Active Ulcerative Colitis American Journal of Gastroenterology. 114: S438-S438. DOI: 10.14309/01.Ajg.0000592524.80798.9B |
0.412 |
|
| 2019 |
Bajaj JS, Fagan A, Sikaroodi M, Kakiyama G, Pandak W, Takei H, Gavis E, Hylemon P, Heuman D, Nittono H, Gillevet P. SAT-012-Alterations in skin microbiota, serum bile acids and autotaxin modulate itching intensity in patients with cirrhosis Journal of Hepatology. 70: e630. DOI: 10.1016/S0618-8278(19)31255-1 |
0.361 |
|
| 2019 |
Liu R, Li X, Zhu W, Zhao D, Wang Y, Kwong E, Alruwaili W, Hinton M, Yang H, Xiang D, Wang X, Gurley E, Pandak WM, Hylemon P, Zhou H. 771 – Bile Acid-Induced Activation of Sphingosine Kinase 2 Contributes to Intestinal Barrier Dysfunction and Hepatic Inflammation in Multi-Drug Resistance 2 Gene Deficient Mice Gastroenterology. 156: S-1215. DOI: 10.1016/S0016-5085(19)40022-X |
0.359 |
|
| 2019 |
Bajaj JS, Fagan A, Sikaroodi M, Kakiyama G, Pandak WM, Nittono H, Takei H, Gavis E, Hylemon P, Heuman D, Gillevet PM. 408 – Alterations in Skin Microbiota, Serum Bile Acids and Autotaxin Modulate Itching Intensity in Patients with Cirrhosis Gastroenterology. 156: S-1196-S-1197. DOI: 10.1016/S0016-5085(19)39968-8 |
0.357 |
|
| 2018 |
Kang JD, Myers CJ, Harris SC, Kakiyama G, Lee IK, Yun BS, Matsuzaki K, Furukawa M, Min HK, Bajaj JS, Zhou H, Hylemon PB. Bile Acid 7α-Dehydroxylating Gut Bacteria Secrete Antibiotics that Inhibit Clostridium difficile: Role of Secondary Bile Acids. Cell Chemical Biology. PMID 30482679 DOI: 10.1016/J.Chembiol.2018.10.003 |
0.413 |
|
| 2018 |
Liu R, Li X, Hylemon PB, Zhou H. Conjugated bile acids promote invasive growth of esophageal adenocarcinoma cells and cancer stem cell expansion via sphingosine 1-phosphate receptor 2 (S1PR2)-mediated YAP activation. The American Journal of Pathology. PMID 29963993 DOI: 10.1016/J.Ajpath.2018.05.015 |
0.311 |
|
| 2018 |
Bajaj JS, Acharya C, Fagan A, White MB, Gavis E, Heuman DM, Hylemon PB, Fuchs M, Puri P, Schubert ML, Sanyal AJ, Sterling RK, Stravitz RT, Siddiqui MS, Luketic V, et al. Proton Pump Inhibitor Initiation and Withdrawal affects Gut Microbiota and Readmission Risk in Cirrhosis. The American Journal of Gastroenterology. PMID 29872220 DOI: 10.1038/S41395-018-0085-9 |
0.304 |
|
| 2018 |
Hylemon PB, Harris SC, Ridlon JM. Metabolism of hydrogen gases and bile acids in the gut microbiome. Febs Letters. PMID 29683480 DOI: 10.1002/1873-3468.13064 |
0.669 |
|
| 2018 |
Bajaj JS, Kakiyama G, Savidge T, Takei H, Kassam ZA, Fagan A, Gavis EA, Pandak WM, Nittono H, Hylemon PB, Boonma P, Haag A, Heuman DM, Fuchs M, John B, et al. Antibiotic-Associated Disruption of Microbiota Composition and Function in Cirrhosis is Restored by Fecal Transplant. Hepatology (Baltimore, Md.). PMID 29665102 DOI: 10.1002/Hep.30037 |
0.339 |
|
| 2018 |
Harris SC, Devendran S, Méndez-García C, Mythen SM, Wright CL, Fields CJ, Hernandez AG, Cann I, Hylemon PB, Ridlon JM. Bile acid oxidation by Eggerthella lenta strains C592 and DSM 2243. Gut Microbes. 1-58. PMID 29617190 DOI: 10.1080/19490976.2018.1458180 |
0.677 |
|
| 2018 |
Bajaj JS, Kakiyama G, Cox IJ, Nittono H, Takei H, White M, Fagan A, Gavis EA, Heuman DM, Gilles HC, Hylemon P, Taylor-Robinson SD, Legido-Quigley C, Kim M, Xu J, et al. Alterations in Gut Microbial Function Following Liver Transplant. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 29500907 DOI: 10.1002/Lt.25046 |
0.305 |
|
| 2018 |
Li X, Liu R, Huang Z, Gurley EC, Wang X, Wang J, He H, Yang H, Lai G, Zhang L, Bajaj JS, White M, Pandak WM, Hylemon PB, Zhou H. Cholangiocyte-derived exosomal long noncoding RNA H19 promotes cholestatic liver injury in mouse and human. Hepatology (Baltimore, Md.). PMID 29425397 DOI: 10.1002/Hep.29838 |
0.303 |
|
| 2018 |
Harris S, Devendran S, Ridlon JM, Hylemon P. 180 - Eggerthella Lenta Modulates Gut Microbial Physiology by Linking Bile Acid Metabolism to Acetogenesis Gastroenterology. 154: S-46. DOI: 10.1016/S0016-5085(18)30623-1 |
0.682 |
|
| 2017 |
Bajaj JS, Hylemon PB. Gut-Liver Axis Alterations in Alcoholic Liver Disease: Are Bile Acids the Answer? Hepatology (Baltimore, Md.). PMID 29272041 DOI: 10.1002/Hep.29760 |
0.367 |
|
| 2017 |
Harris SC, Devendran S, Alves JMP, Mythen SM, Hylemon PB, Ridlon JM. Identification of a gene encoding a flavoprotein involved in bile acid metabolism by the human gut bacterium Clostridium scindens ATCC 35704. Biochimica Et Biophysica Acta. PMID 29217478 DOI: 10.1016/J.Bbalip.2017.12.001 |
0.686 |
|
| 2017 |
Kwong EK, Li X, Hylemon PB, Zhou H. Sphingosine Kinases/Sphingosine 1-Phosphate Signaling in Hepatic Lipid Metabolism. Current Pharmacology Reports. 3: 176-183. PMID 29130028 DOI: 10.1007/S40495-017-0093-2 |
0.361 |
|
| 2017 |
Hylemon PB, Takabe K, Dozmorov M, Nagahashi M, Zhou H. Bile acids as global regulators of hepatic nutrient metabolism. Liver Research. 1: 10-16. PMID 29123941 DOI: 10.1016/J.Livres.2017.03.002 |
0.387 |
|
| 2017 |
Liu R, Li X, Huang Z, Zhao D, Ganesh BS, Lai G, Pandak WM, Hylemon PB, Bajaj JS, Sanyal AJ, Zhou H. CHOP-induced loss of intestinal epithelial stemness contributes to bile duct ligation-induced cholestatic liver injury. Hepatology (Baltimore, Md.). PMID 28926118 DOI: 10.1002/Hep.29540 |
0.359 |
|
| 2017 |
Bajaj JS, Kakiyama G, Zhao D, Takei H, Fagan A, Hylemon P, Zhou H, Pandak WM, Nittono H, Fiehn O, Salzman N, Holtz M, Simpson P, Gavis EA, Heuman DM, et al. Continued Alcohol Misuse in Human Cirrhosis is Associated with An Impaired Gut-Liver Axis. Alcoholism, Clinical and Experimental Research. PMID 28925102 DOI: 10.1111/Acer.13498 |
0.309 |
|
| 2017 |
Puri P, Daita K, Joyce A, Mirshahi F, Santhekadur PK, Cazanave S, Luketic VA, Siddiqui MS, Boyett S, Min HK, Kumar DP, Kohli R, Zhou H, Hylemon PB, Contos MJ, et al. The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids. Hepatology (Baltimore, Md.). PMID 28696585 DOI: 10.1002/Hep.29359 |
0.341 |
|
| 2017 |
Yang J, Sun L, Wang L, Hassan HM, Wang X, Hylemon PB, Wang T, Zhou H, Zhang L, Jiang Z. Activation of Sirt1/FXR Signaling Pathway Attenuates Triptolide-Induced Hepatotoxicity in Rats. Frontiers in Pharmacology. 8: 260. PMID 28536529 DOI: 10.3389/Fphar.2017.00260 |
0.428 |
|
| 2017 |
Wang Y, Aoki H, Yang J, Peng K, Liu R, Li X, Qiang X, Sun L, Gurley EC, Lai G, Zhang L, Liang G, Nagahashi M, Takabe K, Pandak WM, ... Hylemon PB, et al. The role of S1PR2 in bile acid-induced cholangiocyte proliferation and cholestasis-induced liver injury in mice. Hepatology (Baltimore, Md.). PMID 28120434 DOI: 10.1002/Hep.29076 |
0.385 |
|
| 2017 |
Chen T, Huang Z, Liu R, Yang J, Hylemon PB, Zhou H. Sphingosine-1 phosphate promotes intestinal epithelial cell proliferation via S1PR2. Frontiers in Bioscience (Landmark Edition). 22: 596-608. PMID 27814635 DOI: 10.2741/4505 |
0.313 |
|
| 2017 |
Kakiyama G, Marques D, Takei H, Nittono H, Liu X, Green RM, Erickson S, Rodriguez-Agudo D, Gil G, Bajaj JS, Hylemon P, Zhou H, Pandak WM. Inflammasome Activation by Chronic Down Regulation of CYP7B1 and its Causative Increased Oxysterol Accumulation, Represents the Key Initial Step in Fatty Liver's Progression Toward Inflammation Gastroenterology. 152: S1069. DOI: 10.1016/S0016-5085(17)33610-7 |
0.364 |
|
| 2016 |
Kang DJ, Kakiyama G, Betrapally NS, Herzog J, Nittono H, Hylemon PB, Zhou H, Carroll I, Yang J, Gillevet PM, Jiao C, Takei H, Pandak WM, Iida T, Heuman DM, et al. Rifaximin Exerts Beneficial Effects Independent of its Ability to Alter Microbiota Composition. Clinical and Translational Gastroenterology. 7: e187. PMID 27560928 DOI: 10.1038/Ctg.2016.44 |
0.334 |
|
| 2016 |
Nagahashi M, Yuza K, Hirose Y, Nakajima M, Ramanathan R, Hait NC, Hylemon PB, Zhou H, Takabe K, Wakai T. The roles of bile acids and sphingosine-1-phosphate signaling in the hepato-biliary diseases. Journal of Lipid Research. PMID 27459945 DOI: 10.1194/Jlr.R069286 |
0.419 |
|
| 2016 |
Kang DJ, Betrapally NS, Ghosh SA, Sartor RB, Hylemon PB, Gillevet PM, Sanyal AJ, Heuman DM, Carl D, Zhou H, Liu R, Wang X, Yang J, Jiao C, Herzog J, et al. Gut microbiota drive the development of neuro-inflammatory response in cirrhosis. Hepatology (Baltimore, Md.). PMID 27339732 DOI: 10.1002/Hep.28696 |
0.321 |
|
| 2016 |
Li X, Liu R, Luo L, Yu L, Chen X, Sun L, Wang T, Hylemon PB, Zhou H, Jiang Z, Zhang L. Role of AMP-activated protein kinase α1 in 17α-ethinylestradiol-induced cholestasis in rats. Archives of Toxicology. PMID 27090119 DOI: 10.1007/S00204-016-1697-8 |
0.369 |
|
| 2016 |
Ridlon JM, Harris SC, Bhowmik S, Kang DJ, Hylemon PB. Consequences of bile salt biotransformations by intestinal bacteria. Gut Microbes. 7: 22-39. PMID 26939849 DOI: 10.1080/19490976.2015.1127483 |
0.715 |
|
| 2015 |
Bhowmik S, Chiu HP, Jones DH, Chiu HJ, Miller MD, Xu Q, Farr CL, Ridlon JM, Wells JE, Elsliger MA, Wilson IA, Hylemon PB, Lesley SA. Structure and Functional Characterization of a Bile Acid 7α Dehydratase BaiE in Secondary Bile Acid Synthesis. Proteins. PMID 26650892 DOI: 10.1002/Prot.24971 |
0.689 |
|
| 2015 |
Kwong E, Li Y, Hylemon PB, Zhou H. Bile acids and sphingosine-1-phosphate receptor 2 in hepatic lipid metabolism. Acta Pharmaceutica Sinica. B. 5: 151-157. PMID 26579441 DOI: 10.1016/J.Apsb.2014.12.009 |
0.407 |
|
| 2015 |
Liu R, Li X, Luo L, Qiang X, Hylemon PB, Jiang Z, Zhang L, Zhou H. Taurocholate Induces Cyclooxygenase-2 Expression via the Sphingosine 1-phosphate Receptor 2 in a Human Cholangiocarcinoma Cell Line. The Journal of Biological Chemistry. PMID 26518876 DOI: 10.1074/Jbc.M115.668277 |
0.333 |
|
| 2015 |
Kang DJ, Hylemon PB, Bajaj JS. Fecal transplant to mitigate hyperammonemia and hepatic encephalopathy in animal models. Annals of Hepatology. 14: 762-3. PMID 26256908 DOI: 10.1016/S1665-2681(19)30774-4 |
0.316 |
|
| 2015 |
Ridlon JM, Kang DJ, Hylemon PB, Bajaj JS. Gut microbiota, cirrhosis, and alcohol regulate bile acid metabolism in the gut. Digestive Diseases (Basel, Switzerland). 33: 338-45. PMID 26045267 DOI: 10.1159/000371678 |
0.706 |
|
| 2015 |
Gu S, Cao B, Sun R, Tang Y, Paletta JL, Wu XL, Liu L, Zha W, Zhao C, Li Y, Ridlon JM, Hylemon PB, Zhou H, Aa J, Wang G. Correction: A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine. Molecular Biosystems. 11: 664. PMID 26039924 DOI: 10.1039/c4mb90042a |
0.588 |
|
| 2015 |
Bajaj JS, Betrapally NS, Hylemon PB, Heuman DM, Daita K, White MB, Unser A, Thacker LR, Sanyal AJ, Kang DJ, Sikaroodi M, Gillevet PM. Salivary microbiota reflects changes in gut microbiota in cirrhosis with hepatic encephalopathy. Hepatology (Baltimore, Md.). PMID 25820757 DOI: 10.1002/Hep.27819 |
0.341 |
|
| 2015 |
Gu S, Cao B, Sun R, Tang Y, Paletta JL, Wu XL, Liu L, Zha W, Zhao C, Li Y, Ridlon JM, Hylemon PB, Zhou H, Aa J, Wang G. Correction: A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine. Molecular Biosystems. 11: 664. PMID 25535027 DOI: 10.1039/C4Mb90042A |
0.61 |
|
| 2015 |
Gu S, Cao B, Sun R, Tang Y, Paletta JL, Wu XL, Liu L, Zha W, Zhao C, Li Y, Radlon JM, Hylemon PB, Zhou H, Aa J, Wang G. A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine. Molecular Biosystems. 11: 463-74. PMID 25411028 DOI: 10.1039/c4mb00500g |
0.322 |
|
| 2015 |
Nagahashi M, Takabe K, Liu R, Peng K, Wang X, Wang Y, Hait NC, Wang X, Allegood JC, Yamada A, Aoyagi T, Liang J, Pandak WM, Spiegel S, Hylemon PB, et al. Conjugated bile acid-activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression. Hepatology (Baltimore, Md.). 61: 1216-26. PMID 25363242 DOI: 10.1002/Hep.27592 |
0.409 |
|
| 2015 |
Kang D, Hylemon P, Sartor R, Kakiyama G, Gillevet P, Heuman D, Pandak W, Ridlon J, Fiehn O, Grapov D, Bajaj J. O090 : Humanization of germ-free mice with alcoholic cirrhotic microbiota, but not healthy microbiota, induces bacterial translocation and a pro-inflammatory milieu, which is ameliorated with lactobacillus GG Journal of Hepatology. 62: S239-S240. DOI: 10.1016/S0168-8278(15)30109-4 |
0.592 |
|
| 2015 |
Kang D, Hylemon P, Ridlon JM, Pandak WM, Heuman DM, Bajaj JS. Sa1017 Diminished Fecal Secondary Bile Acids May Predispose Patients With Cirrhosis to C. difficile Infection and Attenuate the Action of Rifaximin Gastroenterology. 148: S-1008. DOI: 10.1016/S0016-5085(15)33439-9 |
0.65 |
|
| 2015 |
Kang D, Hylemon P, Sartor RB, Kakiyama G, Gillevet PM, Heuman DM, Pandak WM, Ridlon JM, Grapov D, Fiehn O, Bajaj JS. 281 Humanization of Germ-Free Mice With Alcoholic Cirrhotic Microbiota, but Not Healthy Microbiota, Induces Bacterial Translocation and a Pro-Inflammatory Milieu, Which Is Ameliorated With Lactobacillus GG Gastroenterology. 148: S-975-S-976. DOI: 10.1016/S0016-5085(15)33333-3 |
0.628 |
|
| 2014 |
Bajaj JS, Cox IJ, Betrapally NS, Heuman DM, Schubert ML, Ratneswaran M, Hylemon PB, White MB, Daita K, Noble NA, Sikaroodi M, Williams R, Crossey MM, Taylor-Robinson SD, Gillevet PM. Systems biology analysis of omeprazole therapy in cirrhosis demonstrates significant shifts in gut microbiota composition and function. American Journal of Physiology. Gastrointestinal and Liver Physiology. 307: G951-7. PMID 25258407 DOI: 10.1152/Ajpgi.00268.2014 |
0.33 |
|
| 2014 |
Srivastava J, Robertson CL, Rajasekaran D, Gredler R, Siddiq A, Emdad L, Mukhopadhyay ND, Ghosh S, Hylemon PB, Gil G, Shah K, Bhere D, Subler MA, Windle JJ, Fisher PB, et al. AEG-1 regulates retinoid X receptor and inhibits retinoid signaling. Cancer Research. 74: 4364-77. PMID 25125681 DOI: 10.1158/0008-5472.Can-14-0421 |
0.306 |
|
| 2014 |
Zhou H, Hylemon PB. Bile acids are nutrient signaling hormones. Steroids. 86: 62-8. PMID 24819989 DOI: 10.1016/J.Steroids.2014.04.016 |
0.413 |
|
| 2014 |
Liu R, Zhao R, Zhou X, Liang X, Campbell DJ, Zhang X, Zhang L, Shi R, Wang G, Pandak WM, Sirica AE, Hylemon PB, Zhou H. Conjugated bile acids promote cholangiocarcinoma cell invasive growth through activation of sphingosine 1-phosphate receptor 2. Hepatology (Baltimore, Md.). 60: 908-18. PMID 24700501 DOI: 10.1002/Hep.27085 |
0.369 |
|
| 2014 |
Kakiyama G, Hylemon PB, Zhou H, Pandak WM, Heuman DM, Kang DJ, Takei H, Nittono H, Ridlon JM, Fuchs M, Gurley EC, Wang Y, Liu R, Sanyal AJ, Gillevet PM, et al. Colonic inflammation and secondary bile acids in alcoholic cirrhosis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G929-37. PMID 24699327 DOI: 10.1152/Ajpgi.00315.2013 |
0.641 |
|
| 2014 |
Ridlon JM, Kang DJ, Hylemon PB, Bajaj JS. Bile acids and the gut microbiome. Current Opinion in Gastroenterology. 30: 332-8. PMID 24625896 DOI: 10.1097/Mog.0000000000000057 |
0.688 |
|
| 2014 |
Bajaj JS, Heuman DM, Hylemon PB, Sanyal AJ, White MB, Monteith P, Noble NA, Unser AB, Daita K, Fisher AR, Sikaroodi M, Gillevet PM. Altered profile of human gut microbiome is associated with cirrhosis and its complications. Journal of Hepatology. 60: 940-7. PMID 24374295 DOI: 10.1016/J.Jhep.2013.12.019 |
0.312 |
|
| 2014 |
Bajaj J, Heuman D, Hylemon P, Sikaroodi M, Ridlon J, Pandak W, Schubert M, Fuchs M, White M, Daita K, Gillevet P. P335 DYSFUNCTIONAL GUT MICROBIOTA IN ILEO-COLONIC MUCOSA AND STOOL IN ALCOHOLIC CIRRHOSIS IS ASSOCIATED WITH ENDOTOXEMIA: IMPLICATIONS FOR BACTERIAL TRANSLOCATION Journal of Hepatology. 60: S178-S179. DOI: 10.1016/S0168-8278(14)60497-9 |
0.626 |
|
| 2013 |
Ridlon JM, Alves JM, Hylemon PB, Bajaj JS. Cirrhosis, bile acids and gut microbiota: unraveling a complex relationship. Gut Microbes. 4: 382-7. PMID 23851335 DOI: 10.4161/Gmic.25723 |
0.71 |
|
| 2013 |
Ridlon JM, Ikegawa S, Alves JM, Zhou B, Kobayashi A, Iida T, Mitamura K, Tanabe G, Serrano M, De Guzman A, Cooper P, Buck GA, Hylemon PB. Clostridium scindens: a human gut microbe with a high potential to convert glucocorticoids into androgens. Journal of Lipid Research. 54: 2437-49. PMID 23772041 DOI: 10.1194/Jlr.M038869 |
0.651 |
|
| 2013 |
Bajaj JS, Heuman DM, Sanyal AJ, Hylemon PB, Sterling RK, Stravitz RT, Fuchs M, Ridlon JM, Daita K, Monteith P, Noble NA, White MB, Fisher A, Sikaroodi M, Rangwala H, et al. Modulation of the metabiome by rifaximin in patients with cirrhosis and minimal hepatic encephalopathy. Plos One. 8: e60042. PMID 23565181 DOI: 10.1371/Journal.Pone.0060042 |
0.646 |
|
| 2013 |
Kakiyama G, Pandak WM, Gillevet PM, Hylemon PB, Heuman DM, Daita K, Takei H, Muto A, Nittono H, Ridlon JM, White MB, Noble NA, Monteith P, Fuchs M, Thacker LR, et al. Modulation of the fecal bile acid profile by gut microbiota in cirrhosis. Journal of Hepatology. 58: 949-55. PMID 23333527 DOI: 10.1016/J.Jhep.2013.01.003 |
0.657 |
|
| 2013 |
Bajaj J, Heuman D, Sanyal A, Hylemon P, Sterling R, Stravitz R, Fuchs M, Ridlon J, Daita K, Monteith P, White M, Noble N, Fisher A, Sikaroodi M, Rangwala H, et al. 192 RIFAXIMIN IMPROVES COGNITION AND ENDOTOXEMIA IN MINIMAL HEPATIC ENCEPHALOPATHY BY SHIFTING GUT MICROBIAL FUNCTIONALITY WITHOUT ALTERING THEIR ABUNDANCE Journal of Hepatology. 58: S84-S85. DOI: 10.1016/S0168-8278(13)60194-4 |
0.621 |
|
| 2012 |
Bajaj JS, Hylemon PB, Ridlon JM, Heuman DM, Daita K, White MB, Monteith P, Noble NA, Sikaroodi M, Gillevet PM. Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G675-85. PMID 22821944 DOI: 10.1152/Ajpgi.00152.2012 |
0.632 |
|
| 2012 |
Srivastava J, Siddiq A, Emdad L, Santhekadur PK, Chen D, Gredler R, Shen XN, Robertson CL, Dumur CI, Hylemon PB, Mukhopadhyay ND, Bhere D, Shah K, Ahmad R, Giashuddin S, et al. Astrocyte elevated gene-1 promotes hepatocarcinogenesis: novel insights from a mouse model. Hepatology (Baltimore, Md.). 56: 1782-91. PMID 22689379 DOI: 10.1002/Hep.25868 |
0.317 |
|
| 2012 |
Bajaj JS, Gillevet PM, Patel NR, Ahluwalia V, Ridlon JM, Kettenmann B, Schubert CM, Sikaroodi M, Heuman DM, Crossey MM, Bell DE, Hylemon PB, Fatouros PP, Taylor-Robinson SD. A longitudinal systems biology analysis of lactulose withdrawal in hepatic encephalopathy. Metabolic Brain Disease. 27: 205-15. PMID 22527995 DOI: 10.1007/S11011-012-9303-0 |
0.606 |
|
| 2012 |
Xu L, Shen S, Ma Y, Kim JK, Rodriguez-Agudo D, Heuman DM, Hylemon PB, Pandak WM, Ren S. 25-Hydroxycholesterol-3-sulfate attenuates inflammatory response via PPARγ signaling in human THP-1 macrophages. American Journal of Physiology. Endocrinology and Metabolism. 302: E788-99. PMID 22275753 DOI: 10.1152/Ajpendo.00337.2011 |
0.334 |
|
| 2012 |
Ridlon JM, Hylemon PB. Identification and characterization of two bile acid coenzyme A transferases from Clostridium scindens, a bile acid 7α-dehydroxylating intestinal bacterium. Journal of Lipid Research. 53: 66-76. PMID 22021638 DOI: 10.1194/Jlr.M020313 |
0.691 |
|
| 2012 |
Bajaj JS, Ridlon JM, Hylemon PB, Thacker LR, Heuman DM, Smith S, Sikaroodi M, Gillevet PM. Linkage of gut microbiome with cognition in hepatic encephalopathy. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G168-75. PMID 21940902 DOI: 10.1152/Ajpgi.00190.2011 |
0.624 |
|
| 2012 |
Studer E, Zhou X, Zhao R, Wang Y, Takabe K, Nagahashi M, Pandak WM, Dent P, Spiegel S, Shi R, Xu W, Liu X, Bohdan P, Zhang L, Zhou H, ... Hylemon PB, et al. Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes. Hepatology (Baltimore, Md.). 55: 267-76. PMID 21932398 DOI: 10.1002/Hep.24681 |
0.381 |
|
| 2012 |
Srivastava J, Siddiq A, Emdad L, Santhekadur PK, Chen D, Gredler R, Shen X, Robertson CL, Stafflinger J, Subler MA, Dumur CI, Hylemon PB, Windle JJ, Fisher PB, Sarkar D. Abstract 1324: Unraveling novel functions of the oncogene Astrocyte elevated gene-1 (AEG-1) contributing to hepatocarcinogenesis employing a transgenic mouse model Cancer Research. 72: 1324-1324. DOI: 10.1158/1538-7445.Am2012-1324 |
0.328 |
|
| 2012 |
Kakiyama G, Ridlon J, Hylemon P, Pandak W, Gillevet P, Heuman D, Daita K, Bajaj J. 116 THE GUT MICROBIOME MODULATES FECAL BILE ACID PROFILE IN PATIENTS WITH CIRRHOSIS Journal of Hepatology. 56: S51. DOI: 10.1016/S0168-8278(12)60130-5 |
0.681 |
|
| 2012 |
Wang Y, Masayuki N, Takabe K, Gurley EC, Hylemon P, Pandak WM, Zhang L, Zhou H. Tu1820 Sphingosine Kinase 2 Deficiency Disrupts Hepatic Lipid Metabolism Gastroenterology. 142: S-1025. DOI: 10.1016/S0016-5085(12)63966-3 |
0.319 |
|
| 2012 |
Li Y, Zhang X, Wang G, Gurley EC, Hylemon P, Pandak WM, Zhou H. 695 18ß-Glycyrrhetinic Acid Prevents Free Fatty Acid-Induced Hepatic Lipotoxicity by Upregulating GRP78 Expression Gastroenterology. 142: S-922. DOI: 10.1016/S0016-5085(12)63578-1 |
0.389 |
|
| 2011 |
Rodriguez-Agudo D, Calderon-Dominguez M, Ren S, Marques D, Redford K, Medina-Torres MA, Hylemon P, Gil G, Pandak WM. Subcellular localization and regulation of StarD4 protein in macrophages and fibroblasts. Biochimica Et Biophysica Acta. 1811: 597-606. PMID 21767660 DOI: 10.1016/J.Bbalip.2011.06.028 |
0.342 |
|
| 2011 |
Bai Q, Xu L, Kakiyama G, Runge-Morris MA, Hylemon PB, Yin L, Pandak WM, Ren S. Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells. Atherosclerosis. 214: 350-6. PMID 21146170 DOI: 10.1016/J.Atherosclerosis.2010.11.021 |
0.34 |
|
| 2010 |
Xu L, Bai Q, Rodriguez-Agudo D, Hylemon PB, Heuman DM, Pandak WM, Ren S. Regulation of hepatocyte lipid metabolism and inflammatory response by 25-hydroxycholesterol and 25-hydroxycholesterol-3-sulfate. Lipids. 45: 821-32. PMID 20700770 DOI: 10.1007/S11745-010-3451-Y |
0.409 |
|
| 2010 |
Cao R, Cronk ZX, Zha W, Sun L, Wang X, Fang Y, Studer E, Zhou H, Pandak WM, Dent P, Gil G, Hylemon PB. Bile acids regulate hepatic gluconeogenic genes and farnesoid X receptor via G(alpha)i-protein-coupled receptors and the AKT pathway. Journal of Lipid Research. 51: 2234-44. PMID 20305288 DOI: 10.1194/Jlr.M004929 |
0.35 |
|
| 2010 |
Ridlon JM, Kang DJ, Hylemon PB. Isolation and characterization of a bile acid inducible 7alpha-dehydroxylating operon in Clostridium hylemonae TN271. Anaerobe. 16: 137-46. PMID 19464381 DOI: 10.1016/J.Anaerobe.2009.05.004 |
0.687 |
|
| 2010 |
Bajaj J, McPhail M, Heuman D, Bell D, Gillevet P, Sikaroodi M, Sanyal A, Sharif M, Ridlon J, Hylemon P, Taylor-Robinson S. 151 URINARY MAGNETIC RESONANCE SPECTROSCOPY IN PATIENTS WITH HEPATIC ENCEPHALOPATHY: CITRATE CORRELATES WITH ASYMMETRIC DIMETHYLARGININE AND GUT MICROBIAL SPECIES AND CAN PREDICT RECURRENCE AFTER LACTULOSE DISCONTINUATION Journal of Hepatology. 52: S67. DOI: 10.1016/S0168-8278(10)60153-5 |
0.607 |
|
| 2010 |
Xu L, Bai Q, Hylemon P, Heuman DM, Pandak WM, Ren S. 313 25-Hydroxycholesterol-3-Sulfate (25HC3S) Attenuates Hepatocyte Intracellular Lipid Levels and Inflammatory Response via LXR/Srebps and IKB/NF-kB Pathways Gastroenterology. 138: S-783. DOI: 10.1016/S0016-5085(10)63608-6 |
0.318 |
|
| 2009 |
Hylemon PB, Zhou H, Pandak WM, Ren S, Gil G, Dent P. Bile acids as regulatory molecules. Journal of Lipid Research. 50: 1509-20. PMID 19346331 DOI: 10.1194/Jlr.R900007-Jlr200 |
0.43 |
|
| 2009 |
Li Y, Zha W, Sun L, Wu X, Gurley EC, Studer E, Hylemon P, Pandak WM, Zhou H. W1242 Glycyrrhetinic Acid Prevents LPS-Induced Inflammatory Response in Macrophages and Intestinal Epithelial Cells Gastroenterology. 136: A-685. DOI: 10.1016/S0016-5085(09)63155-3 |
0.323 |
|
| 2008 |
Ma Y, Xu L, Rodriguez-Agudo D, Li X, Heuman DM, Hylemon PB, Pandak WM, Ren S. 25-Hydroxycholesterol-3-sulfate regulates macrophage lipid metabolism via the LXR/SREBP-1 signaling pathway. American Journal of Physiology. Endocrinology and Metabolism. 295: E1369-79. PMID 18854425 DOI: 10.1152/Ajpendo.90555.2008 |
0.401 |
|
| 2008 |
Wu X, Zhang L, Gurley E, Studer E, Shang J, Wang T, Wang C, Yan M, Jiang Z, Hylemon PB, Sanyal AJ, Pandak WM, Zhou H. Prevention of free fatty acid-induced hepatic lipotoxicity by 18beta-glycyrrhetinic acid through lysosomal and mitochondrial pathways. Hepatology (Baltimore, Md.). 47: 1905-15. PMID 18452148 DOI: 10.1002/Hep.22239 |
0.394 |
|
| 2008 |
Rodriguez-Agudo D, Ren S, Wong E, Marques D, Redford K, Gil G, Hylemon P, Pandak WM. Intracellular cholesterol transporter StarD4 binds free cholesterol and increases cholesteryl ester formation. Journal of Lipid Research. 49: 1409-19. PMID 18403318 DOI: 10.1194/Jlr.M700537-Jlr200 |
0.313 |
|
| 2008 |
Liang G, Li X, Chen L, Yang S, Wu X, Studer E, Gurley E, Hylemon PB, Ye F, Li Y, Zhou H. Synthesis and anti-inflammatory activities of mono-carbonyl analogues of curcumin. Bioorganic & Medicinal Chemistry Letters. 18: 1525-9. PMID 18234497 DOI: 10.1016/J.Bmcl.2007.12.068 |
0.314 |
|
| 2008 |
Kang DJ, Ridlon JM, Moore DR, Barnes S, Hylemon PB. Clostridium scindens baiCD and baiH genes encode stereo-specific 7alpha/7beta-hydroxy-3-oxo-delta4-cholenoic acid oxidoreductases. Biochimica Et Biophysica Acta. 1781: 16-25. PMID 18047844 DOI: 10.1016/J.Bbalip.2007.10.008 |
0.673 |
|
| 2008 |
Ren S, Li X, Ma Y, Rodriguez-Agudo D, Gil G, Hylemon P, Heuman DM, Pandak WM. 168 Regulation of Hepatocyte Lipid Metabolism By 25-Hydroxycholesterol-3-Sulfate (25hc3s) Is Mediated Via the LXR / Srebp-1 Signaling Pathway Gastroenterology. 134: A-756-A-757. DOI: 10.1016/S0016-5085(08)63533-7 |
0.325 |
|
| 2008 |
Wu X, Zhang L, Shang J, Gurley EC, Studer E, Wang X, Hylemon P, Pandak WM, Sanyal AJ, Zhou H. 112 18β-Glycyrrhetinic Acid Prevents Free Fatty Acids/High Fat Diet-Induced Hepatic Toxicity By Inhibiting Cathepsin B Expression and Enzyme Activities Gastroenterology. 134: A-754-A-755. DOI: 10.1016/S0016-5085(08)63524-6 |
0.382 |
|
| 2007 |
Li X, Pandak WM, Erickson SK, Ma Y, Yin L, Hylemon P, Ren S. Biosynthesis of the regulatory oxysterol, 5-cholesten-3beta,25-diol 3-sulfate, in hepatocytes. Journal of Lipid Research. 48: 2587-96. PMID 17890683 DOI: 10.1194/Jlr.M700301-Jlr200 |
0.333 |
|
| 2007 |
Ren S, Li X, Rodriguez-Agudo D, Gil G, Hylemon P, Pandak WM. Sulfated oxysterol, 25HC3S, is a potent regulator of lipid metabolism in human hepatocytes. Biochemical and Biophysical Research Communications. 360: 802-8. PMID 17624300 DOI: 10.1016/J.Bbrc.2007.06.143 |
0.39 |
|
| 2007 |
Xu Z, Tavares-Sanchez OL, Li Q, Fernando J, Rodriguez CM, Studer EJ, Pandak WM, Hylemon PB, Gil G. Activation of bile acid biosynthesis by the p38 mitogen-activated protein kinase (MAPK): hepatocyte nuclear factor-4alpha phosphorylation by the p38 MAPK is required for cholesterol 7alpha-hydroxylase expression. The Journal of Biological Chemistry. 282: 24607-14. PMID 17603092 DOI: 10.1074/Jbc.M611481200 |
0.341 |
|
| 2006 |
Zhou H, Gurley EC, Jarujaron S, Ding H, Fang Y, Xu Z, Pandak WM, Hylemon PB. HIV protease inhibitors activate the unfolded protein response and disrupt lipid metabolism in primary hepatocytes. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G1071-80. PMID 16861219 DOI: 10.1152/Ajpgi.00182.2006 |
0.326 |
|
| 2006 |
Ridlon JM, Hylemon PB. A potential role for resistant starch fermentation in modulating colonic bacterial metabolism and colon cancer risk. Cancer Biology & Therapy. 5: 273-4. PMID 16627972 DOI: 10.4161/Cbt.5.3.2728 |
0.617 |
|
| 2006 |
Rodriguez-Agudo D, Ren S, Hylemon PB, Montañez R, Redford K, Natarajan R, Medina MA, Gil G, Pandak WM. Localization of StarD5 cholesterol binding protein. Journal of Lipid Research. 47: 1168-75. PMID 16534142 DOI: 10.1194/Jlr.M500447-Jlr200 |
0.327 |
|
| 2006 |
Ren S, Hylemon P, Zhang ZP, Rodriguez-Agudo D, Marques D, Li X, Zhou H, Gil G, Pandak WM. Identification of a novel sulfonated oxysterol, 5-cholesten-3beta,25-diol 3-sulfonate, in hepatocyte nuclei and mitochondria. Journal of Lipid Research. 47: 1081-90. PMID 16505492 DOI: 10.1194/Jlr.M600019-Jlr200 |
0.359 |
|
| 2006 |
Ridlon JM, Kang DJ, Hylemon PB. Bile salt biotransformations by human intestinal bacteria. Journal of Lipid Research. 47: 241-59. PMID 16299351 DOI: 10.1194/Jlr.R500013-Jlr200 |
0.692 |
|
| 2005 |
Hall EA, Ren S, Hylemon PB, Redford K, del Castillo A, Gil G, Pandak WM. Mitochondrial cholesterol transport: a possible target in the management of hyperlipidemia. Lipids. 40: 1237-44. PMID 16477808 DOI: 10.1007/S11745-005-1491-0 |
0.352 |
|
| 2005 |
Ridlon JM, McGarr SE, Hylemon PB. Development of methods for the detection and quantification of 7alpha-dehydroxylating clostridia, Desulfovibrio vulgaris, Methanobrevibacter smithii, and Lactobacillus plantarum in human feces. Clinica Chimica Acta; International Journal of Clinical Chemistry. 357: 55-64. PMID 15963794 DOI: 10.1016/J.Cccn.2005.02.004 |
0.666 |
|
| 2005 |
Hall EA, Ren S, Hylemon PB, Rodriguez-Agudo D, Redford K, Marques D, Kang D, Gil G, Pandak WM. Detection of the steroidogenic acute regulatory protein, StAR, in human liver cells. Biochimica Et Biophysica Acta. 1733: 111-9. PMID 15863358 DOI: 10.1016/J.Bbalip.2005.01.004 |
0.379 |
|
| 2005 |
Langston TB, Hylemon PB, Grogan WM. Over-expression of hepatic neutral cytosolic cholesteryl ester hydrolase in mice increases free cholesterol and reduces expression of HMG-CoAR, CYP27, and CYP7A1. Lipids. 40: 31-8. PMID 15825828 DOI: 10.1007/S11745-005-1357-5 |
0.337 |
|
| 2005 |
McGarr SE, Ridlon JM, Hylemon PB. Diet, anaerobic bacterial metabolism, and colon cancer: a review of the literature. Journal of Clinical Gastroenterology. 39: 98-109. PMID 15681903 |
0.621 |
|
| 2004 |
Ren S, Hylemon PB, Marques D, Gurley E, Bodhan P, Hall E, Redford K, Gil G, Pandak WM. Overexpression of cholesterol transporter StAR increases in vivo rates of bile acid synthesis in the rat and mouse. Hepatology (Baltimore, Md.). 40: 910-7. PMID 15382124 DOI: 10.1002/Hep.1840400421 |
0.359 |
|
| 2004 |
Ren S, Hylemon P, Marques D, Hall E, Redford K, Gil G, Pandak WM. Effect of increasing the expression of cholesterol transporters (StAR, MLN64, and SCP-2) on bile acid synthesis. Journal of Lipid Research. 45: 2123-31. PMID 15342684 DOI: 10.1194/Jlr.M400233-Jlr200 |
0.408 |
|
| 2004 |
Williams K, Rao YP, Natarajan R, Pandak WM, Hylemon PB. Indinavir alters sterol and fatty acid homeostatic mechanisms in primary rat hepatocytes by increasing levels of activated sterol regulatory element-binding proteins and decreasing cholesterol 7alpha-hydroxylase mRNA levels. Biochemical Pharmacology. 67: 255-67. PMID 14698038 DOI: 10.1016/J.Bcp.2003.08.044 |
0.382 |
|
| 2004 |
Gupta S, Natarajan R, Payne SG, Studer EJ, Spiegel S, Dent P, Hylemon PB. Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation. The Journal of Biological Chemistry. 279: 5821-8. PMID 14660582 DOI: 10.1074/Jbc.M310979200 |
0.369 |
|
| 2004 |
Fang Y, Han SI, Mitchell C, Gupta S, Studer E, Grant S, Hylemon PB, Dent P. Bile acids induce mitochondrial ROS, which promote activation of receptor tyrosine kinases and signaling pathways in rat hepatocytes Hepatology. 40: 961-971. DOI: 10.1002/Hep.1840400427 |
0.326 |
|
| 2003 |
Ren S, Marques D, Redford K, Hylemon PB, Gil G, Vlahcevic ZR, Pandak WM. Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in the rat. Metabolism: Clinical and Experimental. 52: 636-42. PMID 12759897 DOI: 10.1053/Meta.2003.50106 |
0.41 |
|
| 2003 |
Wells JE, Williams KB, Whitehead TR, Heuman DM, Hylemon PB. Development and application of a polymerase chain reaction assay for the detection and enumeration of bile acid 7alpha-dehydroxylating bacteria in human feces. Clinica Chimica Acta; International Journal of Clinical Chemistry. 331: 127-34. PMID 12691873 DOI: 10.1016/S0009-8981(03)00115-3 |
0.419 |
|
| 2003 |
Rao Y, Williams K, Pandak WM, Hylemon PB. Mechanism for dysregulation of hepatic lipid metabolism by indinavir: Inceasing level of activated sterol regulatory element-bindin protein (SREBP) and decreasing cholesterol-7 alpha-hydroxylase mRNA levels Gastroenterology. 124: A727. DOI: 10.1016/S0016-5085(03)83674-0 |
0.344 |
|
| 2003 |
Gupta S, Studer EJ, Payne SG, Dent P, Hylemon PB. Deoxycholic acid activates the c-Jun N-terminal kinase (JNK) pathway via activation of the FAS receptor Gastroenterology. 124: A727. DOI: 10.1016/S0016-5085(03)83673-9 |
0.301 |
|
| 2003 |
Pandak WM, Ren S, Marques D, Redford K, Gurley E, Bodham P, Hall E, Gil G, Hylemon P. Overexpression of the mitochondrial cholesterol transport protein, StARD1, increases in vivo rates of bile acid synthesis in the rat and the mouse Gastroenterology. 124: A698. DOI: 10.1016/S0016-5085(03)83530-8 |
0.323 |
|
| 2002 |
Pandak WM, Ren S, Marques D, Hall E, Redford K, Mallonee D, Bohdan P, Heuman D, Gil G, Hylemon P. Transport of cholesterol into mitochondria is rate-limiting for bile acid synthesis via the alternative pathway in primary rat hepatocytes. The Journal of Biological Chemistry. 277: 48158-64. PMID 12368294 DOI: 10.1074/Jbc.M205244200 |
0.404 |
|
| 2002 |
Gerbod-Giannone MC, Del Castillo-Olivares A, Janciauskiene S, Gil G, Hylemon PB. Suppression of cholesterol 7alpha-hydroxylase transcription and bile acid synthesis by an alpha1-antitrypsin peptide via interaction with alpha1-fetoprotein transcription factor. The Journal of Biological Chemistry. 277: 42973-80. PMID 12223476 DOI: 10.1074/Jbc.M205089200 |
0.752 |
|
| 2002 |
Gupta S, Pandak WM, Hylemon PB. LXR alpha is the dominant regulator of CYP7A1 transcription. Biochemical and Biophysical Research Communications. 293: 338-43. PMID 12054605 DOI: 10.1016/S0006-291X(02)00229-2 |
0.378 |
|
| 2002 |
Pandak WM, Hylemon PB, Ren S, Marques D, Gil G, Redford K, Mallonee D, Vlahcevic ZR. Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in primary cultures of rat hepatocytes. Hepatology (Baltimore, Md.). 35: 1400-8. PMID 12029625 DOI: 10.1053/Jhep.2002.33200 |
0.43 |
|
| 2002 |
Rao YP, Studer EJ, Stravitz RT, Gupta S, Qiao L, Dent P, Hylemon PB. Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes. Hepatology (Baltimore, Md.). 35: 307-14. PMID 11826403 DOI: 10.1053/Jhep.2002.31104 |
0.343 |
|
| 2001 |
Thomas LA, Veysey MJ, French G, Hylemon PB, Murphy GM, Dowling RH. Bile acid metabolism by fresh human colonic contents: a comparison of caecal versus faecal samples. Gut. 49: 835-42. PMID 11709519 DOI: 10.1136/Gut.49.6.835 |
0.326 |
|
| 2001 |
Pandak WM, Schwarz C, Hylemon PB, Mallonee D, Valerie K, Heuman DM, Fisher RA, Redford K, Vlahcevic ZR. Effects of CYP7A1 overexpression on cholesterol and bile acid homeostasis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G878-89. PMID 11557507 DOI: 10.1152/Ajpgi.2001.281.4.G878 |
0.406 |
|
| 2001 |
Hall E, Hylemon P, Vlahcevic Z, Mallonee D, Valerie K, Avadhani N, Pandak W. Overexpression of CYP27 in hepatic and extrahepatic cells: role in the regulation of cholesterol homeostasis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G293-301. PMID 11408283 DOI: 10.1152/Ajpgi.2001.281.1.G293 |
0.367 |
|
| 2001 |
Pandak WM, Bohdan P, Franklund C, Mallonee DH, Eggertsen G, Björkhem I, Gil G, Vlahcevic ZR, Hylemon PB. Expression of sterol 12α-hydroxylase alters bile acid pool composition in primary rat hepatocytes and in vivo Gastroenterology. 120: 1801-1809. PMID 11375960 DOI: 10.1053/Gast.2001.24833 |
0.376 |
|
| 2001 |
Pandak WM, Hylemon PB, Bohdan P, Bjorkhem I, Eggertsen G, Vlahcevic ZR. Overexpression of sterol 12α-hydroxylase (CYP8b1): Effect on rates of cholic acid (CA) synthesis and alteration in bile acid pool composition Gastroenterology. 120: A1. DOI: 10.1016/S0016-5085(08)80003-0 |
0.356 |
|
| 2000 |
Gupta S, Todd Stravitz R, Pandak WM, Müller M, Reno Vlahcevic Z, Hylemon PB. Regulation of multidrug resistance 2 P-glycoprotein expression by bile salts in rats and in primary cultures of rat hepatocytes Hepatology. 32: 341-347. PMID 10915741 DOI: 10.1053/Jhep.2000.9605 |
0.33 |
|
| 2000 |
Vlahcevic ZR, Eggertsen G, Björkhem I, Hylemon PB, Redford K, Pandak WM. Regulation of sterol 12α-hydroxylase and cholic acid biosynthesis in the rat Gastroenterology. 118: 599-607. PMID 10702212 DOI: 10.1016/S0016-5085(00)70267-8 |
0.333 |
|
| 2000 |
Wells JE, Hylemon PB. Identification and characterization of a bile acid 7α-dehydroxylation operon in Clostridium sp. strain TO-931, a highly active 7α-dehydroxylating strain isolated from human feces Applied and Environmental Microbiology. 66: 1107-1113. PMID 10698778 DOI: 10.1128/Aem.66.3.1107-1113.2000 |
0.337 |
|
| 2000 |
Wells JE, Berr F, Thomas LA, Dowling RH, Hylemon PB. Isolation and characterization of cholic acid 7alpha-dehydroxylating fecal bacteria from cholesterol gallstone patients. Journal of Hepatology. 32: 4-10. PMID 10673060 DOI: 10.1016/S0168-8278(00)80183-X |
0.413 |
|
| 2000 |
Hall EA, Vlahcevic ZR, Hylemon PB, Mallonee D, Pandak WM. Sterol 27-hydroxylase is a tissue specific regulator of cholesterol and bile acid synthesis Gastroenterology. 118: A999. DOI: 10.1016/S0016-5085(00)86144-2 |
0.365 |
|
| 2000 |
Pandak WM, Lijun Z, Hylemon PB, Vlahcevic ZR. Regulation of oxysterol 7A-hydroxylase (CYP7b1) in primary cultures of rat hepatocytes by bile acids (BA), cholesterol (chol), cAMP and phorbol ester Gastroenterology. 118: A998. DOI: 10.1016/S0016-5085(00)86140-5 |
0.339 |
|
| 2000 |
Gupta S, Stravitz RT, Dent P, Vlahcevic ZR, Hylemon PB. Bile acid induced signal transductive pathways involved in regulation of cholesterol 7a-hydroxylase(CYP7a1) transcription Gastroenterology. 118: A2. DOI: 10.1016/S0016-5085(00)82073-9 |
0.412 |
|
| 1999 |
Rao YP, Vlahcevic ZR, Stravitz RT, Mallonee DH, Mullick J, Avadhani NG, Hylemon PB. Down-regulation of the rat hepatic sterol 27-hydroxylasegene by bile acids in transfected primary hepatocytes: Possible role of hepatic nuclear factor 1α Journal of Steroid Biochemistry and Molecular Biology. 70: 1-14. PMID 10528998 DOI: 10.1016/S0960-0760(99)00099-0 |
0.371 |
|
| 1998 |
Hylemon PB, Harder J. Biotransformation of monoterpenes, bile acids, and other isoprenoids in anaerobic ecosystems Fems Microbiology Reviews. 22: 475-488. PMID 9990726 DOI: 10.1016/S0168-6445(98)00027-8 |
0.304 |
|
| 1998 |
Ghosh S, Natarajan R, Pandak WM, Hylemon PB, Grogan WM. Regulation of hepatic neutral cholesteryl ester hydrolase by hormones and changes in cholesterol flux. The American Journal of Physiology. 274: G662-8. PMID 9575847 DOI: 10.1152/Ajpgi.1998.274.4.G662 |
0.338 |
|
| 1998 |
Coleman JP, Kirby LC, Setchell KD, Hylemon PB, Pandak M, Heuman DM, Vlahcevic ZR. Metabolic fate and hepatocyte toxicity of reverse amide analogs of conjugated ursodeoxycholate in the rat. The Journal of Steroid Biochemistry and Molecular Biology. 64: 91-101. PMID 9569014 DOI: 10.1016/S0960-0760(97)00138-6 |
0.408 |
|
| 1997 |
Vlahcevic ZR, Stravitz RT, Heuman DM, Hylemon PB, Pandak WM. Quantitative estimations of the contribution of different bile acid pathways to total bile acid synthesis in the rat Gastroenterology. 113: 1949-1957. PMID 9394735 DOI: 10.1016/S0016-5085(97)70015-5 |
0.426 |
|
| 1997 |
Doerner KC, Takamine F, LaVoie CP, Mallonee DH, Hylemon PB. Assessment of fecal bacteria with bile acid 7α-dehydroxylating activity for the presence of bai-like genes Applied and Environmental Microbiology. 63: 1185-1188. PMID 9055436 DOI: 10.1128/Aem.63.3.1185-1188.1997 |
0.338 |
|
| 1996 |
Mallonee DH, Hylemon PB. Sequencing and expression of a gene encoding a bile acid transporter from Eubacterium sp. strain VPI 12708 Journal of Bacteriology. 178: 7053-7058. PMID 8955384 DOI: 10.1128/Jb.178.24.7053-7058.1996 |
0.382 |
|
| 1996 |
Vlahcevic ZR, Jairath SK, Heuman DM, Stravitz RT, Hylemon PB, Avadhani NG, Pandak WM. Transcriptional regulation of hepatic sterol 27-hydroxylase by bile acids American Journal of Physiology - Gastrointestinal and Liver Physiology. 270. PMID 8928794 DOI: 10.1152/Ajpgi.1996.270.4.G646 |
0.345 |
|
| 1996 |
Stravitz RT, Rao YP, Vlahcevic ZR, Gurley EC, Jarvis WD, Hylemon PB, Holmes H. Hepatocellular protein kinase C activation by bile acids: Implications for regulation of cholesterol 7α-hydroxylase American Journal of Physiology - Gastrointestinal and Liver Physiology. 271. PMID 8770045 DOI: 10.1152/Ajpgi.1996.271.2.G293 |
0.37 |
|
| 1996 |
Stravitz RT, Vlahcevic ZR, Russell TL, Heizer ML, Avadhani NG, Hylemon PB. Regulation of sterol 27-hydroxylase and an alternative pathway of bile acid biosynthesis in primary cultures of rat hepatocytes. The Journal of Steroid Biochemistry and Molecular Biology. 57: 337-47. PMID 8639470 DOI: 10.1016/0960-0760(95)00282-0 |
0.426 |
|
| 1995 |
Pandak WM, Heuman DM, Hylemon PB, Chiang JYL, Reno Vlahcevic Z. Failure of intravenous infusion of taurocholate to down-regulate cholesterol 7α-hydroxylase in rats with biliary fistulas Gastroenterology. 108: 533-544. PMID 7835596 DOI: 10.1016/0016-5085(95)90083-7 |
0.379 |
|
| 1995 |
Mallonee DH, Lijewski MA, Hylemon PB. Expression in Escherichia coli and characterization of a bile acid-inducible 3α-hydroxysteroid dehydrogenase from Eubacterium sp. strain VPI 12708 Current Microbiology. 30: 259-263. PMID 7766153 DOI: 10.1007/Bf00295498 |
0.381 |
|
| 1995 |
Baron SF, Hylemon PB. Expression of the bile acid-inducible NADH:flavin oxidoreductase gene of Eubacterium sp. VPI 12708 in Escherichia coli Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 1249: 145-154. PMID 7599167 DOI: 10.1016/0167-4838(95)00034-R |
0.403 |
|
| 1993 |
Franklund CV, Baron SF, Hylemon PB. Characterization of the baiH gene encoding a bile acid-inducible NADH:flavin oxidoreductase from Eubacterium sp. strain VPI 12708 Journal of Bacteriology. 175: 3002-3012. PMID 8491719 DOI: 10.1128/Jb.175.10.3002-3012.1993 |
0.344 |
|
| 1992 |
Mallonee DH, Adams JL, Hylemon PB. The bile acid-inducible baiB gene from Eubacterium sp. strain VPI 12708 encodes a bile acid-coenzyme A ligase Journal of Bacteriology. 174: 2065-2071. PMID 1551828 DOI: 10.1128/Jb.174.7.2065-2071.1992 |
0.422 |
|
| 1992 |
Vlahcevic ZR, Pandak WM, Heuman DM, Hylemon PB. Function and regulation of hydroxylases involved in the bile acid biosynthesis pathways Seminars in Liver Disease. 12: 403-419. PMID 1465624 |
0.317 |
|
| 1992 |
Heuman DM, Vlahcevic ZR, Pandak WM, Hylemon PB, Kim YS, Lillienau J, Hofmann AF. Effect of cholylsarcosine on hepatic cholesterol and bile acid synthesis and bile secretion in rats Gastroenterology. 103: 1641-1648. PMID 1385253 DOI: 10.1016/0016-5085(92)91190-F |
0.407 |
|
| 1991 |
Hylemon PB, Raynor L, Bohdan PM, Reno Vlahcevic Z. High-performance liquid chromatography assay for 3β-hydroxy-Δ5-C27-steroid oxidoreductase activity in rat liver microsomes Analytical Biochemistry. 193: 256-259. PMID 1872471 DOI: 10.1016/0003-2697(91)90018-O |
0.333 |
|
| 1991 |
Baron SF, Franklund CV, Hylemon PB. Cloning, sequencing, and expression of the gene coding for bile acid 7α-hydroxysteroid dehydrogenase from Eubacterium sp. strain VPI 12708 Journal of Bacteriology. 173: 4558-4569. PMID 1856160 DOI: 10.1128/Jb.173.15.4558-4569.1991 |
0.329 |
|
| 1991 |
Vlahcevic ZR, Heuman DM, Hylemon PB. Regulation of bile acid synthesis Hepatology. 13: 590-600. DOI: 10.1002/Hep.1840130331 |
0.337 |
|
| 1990 |
Gopal-Srivastava R, Mallonee DH, White WB, Hylemon PB. Multiple copies of a bile acid-inducible gene in Eubacterium sp. strain VPI 12708 Journal of Bacteriology. 172: 4420-4426. PMID 2376563 DOI: 10.1128/Jb.172.8.4420-4426.1990 |
0.301 |
|
| 1990 |
Hylemon PB, Bohdan PM, Sirica AE, Heuman DM, Vlahcevic ZR. Cholesterol and bile acid metabolism in cultures of primary rat bile ductular epithelial cells Hepatology. 11: 982-988. PMID 2365295 DOI: 10.1002/hep.1840110612 |
0.335 |
|
| 1990 |
Pandak WM, Heuman DM, Hylemon PB, Vlahcevic ZR. Regulation of bile acid synthesis. IV. Interrelationship between cholesterol and bile acid biosynthesis pathways Journal of Lipid Research. 31: 79-90. PMID 2313206 |
0.306 |
|
| 1989 |
Heuman DM, Hylemon PB, Vlahcevic ZR. Regulation of bile acid synthesis. III. Correlation between biliary bile salt hydrophobicity index and the activities of enzymes regulating cholesterol and bile acid synthesis in the rat Journal of Lipid Research. 30: 1161-1171. PMID 2769071 DOI: 10.1016/0270-9139(91)90317-O |
0.306 |
|
| 1988 |
Heuman DM, Vlahcevic ZR, Bailey ML, Hylemon PB. Regulation of bile acid synthesis. II. Effect of bile acid feeding on enzymes regulating hepatic cholesterol and bile acid synthesis in the rat. Hepatology (Baltimore, Md.). 8: 892-7. PMID 3391517 |
0.343 |
|
| 1988 |
Heuman DM, Hernandez CR, Hylemon PB, Kubaska WM, Hartman C, Vlahcevic ZR. Regulation of bile acid synthesis. I. Effects of conjugated ursodeoxycholate and cholate on bile acid synthesis in chronic bile fistula rat Hepatology. 8: 358-365. PMID 3356417 |
0.326 |
|
| 1987 |
Kubaska WM, Gurley EC, Hylemon PB, Heuman DM, Mosbach EH, Vlahcevic ZR. Effects of ursodeoxycholic acid, analogues of ursodeoxycholic acid and combination of bile acids on bile acid synthesis in cultured rat hepatocytes Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 920: 195-204. PMID 3607077 DOI: 10.1016/0005-2760(87)90095-6 |
0.429 |
|
| 1987 |
Coleman JP, White WB, Hylemon PB. Molecular cloning of bile acid 7-dehydroxylase from Eubacterium sp. strain VPI 12708 Journal of Bacteriology. 169: 1516-1521. PMID 3549693 DOI: 10.1128/Jb.169.4.1516-1521.1987 |
0.354 |
|
| 1985 |
Kubaska WM, Gurley EC, Hylemon PB, Guzelian PS, Vlahcevic ZR. Absence of negative feedback control of bile acid biosynthesis in cultured rat hepatocytes Journal of Biological Chemistry. 260: 13459-13463. PMID 4055743 |
0.303 |
|
| 1985 |
Hylemon PB. Chapter 12 Metabolism of bile acids in intestinal microflora New Comprehensive Biochemistry. 12: 331-343. DOI: 10.1016/S0167-7306(08)60688-2 |
0.446 |
|
| 1984 |
Whitehead TR, Vlahcevic ZR, Beg ZH, Hylemon PB. Characterization of active and inactive forms of rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase Archives of Biochemistry and Biophysics. 230: 483-491. PMID 6712250 DOI: 10.1016/0003-9861(84)90428-4 |
0.311 |
|
| 1984 |
Hylemon PB, Moody DP, Cohen BI, Une M, Mosbach EH. Effect of bile acid analogs on 7α-dehydroxylase activity in eubacterium Sp. V.P.I. 12708 Steroids. 44: 329-336. PMID 6545070 DOI: 10.1016/S0039-128X(84)80025-2 |
0.35 |
|
| 1983 |
Hylemon PB, Fricke RJ, Kubaska WM, Cohen BI, Mosbach EH. Metabolism of bile acid oxazoline derivatives by hepatocyte monolayer cultures and intestinal anaerobic bacteria Steroids. 42: 105-114. PMID 6673175 DOI: 10.1016/S0039-128X(83)90132-0 |
0.427 |
|
| 1980 |
A B, Lipsky WRL, Fricke RJ, Hylemon PB. Bile acid induction specificity of 7α-dehydroxylase activity in an intestinal Eubacterium species Steroids. 35: 103-109. PMID 7376208 DOI: 10.1016/0039-128X(80)90115-4 |
0.391 |
|
| 1980 |
Lipsky RH, Hylemon PB. Characterization of a NADH:flavin oxidoreductase induced by cholic acid in a 7 alpha-dehydroxylating intestinal Eubacterium species. Biochimica Et Biophysica Acta. 612: 328-36. PMID 7370273 DOI: 10.1016/0005-2744(80)90115-1 |
0.329 |
|
| 1977 |
Sherrod JA, Hylemon PB. Partial purification and characterization of NAD-dependent 7α-hydroxysteroid dehydrogenase from Bacteroides thetaiotaomicron Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 486: 351-358. PMID 189820 DOI: 10.1016/0005-2760(77)90031-5 |
0.391 |
|
| 1976 |
Hylemon PB, Stellwag EJ. Bile acid biotransformation rates of selected gram-positive and gram-negative intestinal anaerobic bacteria Biochemical and Biophysical Research Communications. 69: 1088-1094. PMID 1275920 DOI: 10.1016/0006-291X(76)90484-8 |
0.339 |
|
| 1976 |
Stellwag EJ, Hylemon PB. Purification and characterization of bile salt hydrolase from Bacteroides fragilis subsp. fragilis Bba - Enzymology. 452: 165-176. PMID 10993 DOI: 10.1016/0005-2744(76)90068-1 |
0.328 |
|
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