Jonathan Angel - Publications

Affiliations: 
Biochemistry, Microbiology and Immunology University of Ottawa, Ottawa, ON, Canada 
Area:
Virology Biology, Molecular Biology, Cell Biology

123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Dufour C, Ruiz MJ, Pagliuzza A, Richard C, Shahid A, Fromentin R, Ponte R, Cattin A, Wiche Salinas TR, Salahuddin S, Sandstrom T, Schinkel SB, Costiniuk CT, Jenabian MA, Ancuta P, ... ... Angel JB, et al. Near full-length HIV sequencing in multiple tissues collected postmortem reveals shared clonal expansions across distinct reservoirs during ART. Cell Reports. 42: 113053. PMID 37676762 DOI: 10.1016/j.celrep.2023.113053  0.418
2023 Swaminathan S, Scorza T, Yero A, Farnos O, Burke Schinkel SC, Angel JB, Jenabian MA. Impact of HIV infection on human thymic regulatory T cell differentiation. Frontiers in Microbiology. 14: 1217801. PMID 37547675 DOI: 10.3389/fmicb.2023.1217801  0.441
2023 Costiniuk CT, Singer J, Lee T, Galipeau Y, McCluskie PS, Arnold C, Langlois MA, Needham J, Jenabian MA, Burchell AN, Samji H, Chambers C, Walmsley S, Ostrowski M, Kovacs C, ... ... Angel JB, et al. Antibody neutralization capacity after COVID-19 vaccination in people with HIV (CIHR Canadian HIV trials network 328). Aids (London, England). PMID 37534695 DOI: 10.1097/QAD.0000000000003680  0.317
2023 Angel JB, Freilich J, Arthurs E, Ban JK, Lachaine J, Chounta V, Harris M. Adherence to oral antiretroviral therapy in Canada, 2010-2020: A retrospective analysis of claims data. Aids (London, England). PMID 37418513 DOI: 10.1097/QAD.0000000000003648  0.329
2023 Alexandrova Y, Yero A, Mboumba Bouassa RS, Comeau E, Samarani S, Brumme ZL, Hull M, Crawley AM, Langlois MA, Angel JB, Cooper CL, Needham J, Lee T, Singer J, Anis AH, et al. SARS-CoV-2 Vaccine-Induced T-Cell Response after Three Doses in People Living with HIV on Antiretroviral Therapy Compared to Seronegative Controls (CTN 328 COVAXHIV Study). Viruses. 15. PMID 36851789 DOI: 10.3390/v15020575  0.322
2022 Klein MB, Young J, Ortiz-Paredes D, Wang S, Walmsley S, Wong A, Martel-Laferrière V, Pick N, Conway B, Angel J, Baril JG, Fraser C, Lebouché B, Tan DHS, Sandre R, et al. Virological Outcomes After Switching to Abacavir/Lamivudine/Dolutegravir Combined with Adherence Support in People Living with HIV with Poor Adherence: A Phase IV, Multicentre Randomized Prospective Open Label Study (TriiADD-CTN 286). Patient Preference and Adherence. 16: 3267-3281. PMID 36536672 DOI: 10.2147/PPA.S379065  0.436
2022 Costiniuk CT, Singer J, Lee T, Langlois MA, Arnold C, Galipeau Y, Needham J, Kulic I, Jenabian MA, Burchell AN, Shamji H, Chambers C, Walmsley S, Ostrowski M, Kovacs C, ... ... Angel JB, et al. COVID-19 vaccine immunogenicity in people with HIV. Aids (London, England). 37: F1-F10. PMID 36476452 DOI: 10.1097/QAD.0000000000003429  0.321
2022 Lessard D, Dube K, Bilodeau M, Keeler P, Margolese S, Rosenes R, Sinyavskaya L, Durand M, Benko E, Kovacs C, Guerlotté C, Tharao WE, Arnold K, Masching R, Taylor D, ... ... Angel JB, et al. Willingness of older Canadians with HIV to participate in HIV cure research near and after the end-of-life: A mixed-method study. Aids Research and Human Retroviruses. PMID 35778845 DOI: 10.1089/AID.2022.0006  0.388
2021 Costiniuk CT, Singer J, Langlois MA, Kulic I, Needham J, Burchell A, Jenabian MA, Walmsley S, Ostrowski M, Kovacs C, Tan D, Harris M, Hull M, Brumme Z, Brockman M, ... ... Angel JB, et al. CTN 328: immunogenicity outcomes in people living with HIV in Canada following vaccination for COVID-19 (HIV-COV): protocol for an observational cohort study. Bmj Open. 11: e054208. PMID 34916326 DOI: 10.1136/bmjopen-2021-054208  0.359
2021 Mohammadzadeh N, Roda W, Branton WG, Clain J, Rabezanahary H, Zghidi-Abouzid O, Gelman BB, Angel JB, Cohen EA, Gill MJ, Li M, Estaquier J, Power C. Lentiviral Infections Persist in Brain despite Effective Antiretroviral Therapy and Neuroimmune Activation. Mbio. 12: e0278421. PMID 34903055 DOI: 10.1128/mBio.02784-21  0.377
2021 Molyer B, Kumar A, Angel JB. SMAC Mimetics as Therapeutic Agents in HIV Infection. Frontiers in Immunology. 12: 780400. PMID 34899741 DOI: 10.3389/fimmu.2021.780400  0.507
2021 Caballero RE, Dong SXM, Gajanayaka N, Ali H, Cassol E, Cameron WD, Korneluk R, Tremblay MJ, Angel JB, Kumar A. Author Correction: Role of RIPK1 in SMAC mimetics-induced apoptosis in primary human HIV-infected macrophages. Scientific Reports. 11: 24008. PMID 34880376 DOI: 10.1038/s41598-021-03517-z  0.396
2021 Caballero RE, Dong SXM, Gajanayaka N, Ali H, Cassol E, Cameron WD, Korneluk R, Tremblay MJ, Angel J, Kumar A. Role of RIPK1 in SMAC mimetics-induced apoptosis in primary human HIV-infected macrophages. Scientific Reports. 11: 22901. PMID 34824340 DOI: 10.1038/s41598-021-02146-w  0.451
2021 Dong SXM, Vizeacoumar FS, Bhanumathy KK, Alli N, Gonzalez-Lopez C, Gajanayaka N, Caballero R, Ali H, Freywald A, Cassol E, Angel JB, Vizeacoumar FJ, Kumar A. Identification of novel genes involved in apoptosis of HIV-infected macrophages using unbiased genome-wide screening. Bmc Infectious Diseases. 21: 655. PMID 34233649 DOI: 10.1186/s12879-021-06346-7  0.474
2021 Planas D, Pagliuzza A, Ponte R, Fert A, Marchand LR, Massanella M, Gosselin A, Mehraj V, Dupuy FP, Isnard S, Goulet JP, Lesage S, Cohen EA, Ghali MP, Angel JB, et al. LILAC pilot study: Effects of metformin on mTOR activation and HIV reservoir persistence during antiretroviral therapy. Ebiomedicine. 65: 103270. PMID 33662832 DOI: 10.1016/j.ebiom.2021.103270  0.432
2021 Sandstrom TS, Ranganath N, Burke Schinkel SC, Salahuddin S, Meziane O, Côté SC, Costiniuk CT, Jenabian MA, Angel JB. HIV-infected macrophages are infected and killed by the interferon-sensitive Rhabdovirus, MG1. Journal of Virology. PMID 33568507 DOI: 10.1128/JVI.01953-20  0.497
2020 McGuinty M, Angel JB, Cooper CL, Cowan J, MacPherson PA, Kumar A, Murthy S, Sy R, Dennehy M, Tremblay N, Byrareddy SN, Cameron DW. Vedolizumab treatment across antiretroviral treatment interruption in chronic HIV infection: the HAVARTI protocol for a pilot dose-ranging clinical trial to assess safety, tolerance, immunological and virological activity. Bmj Open. 10: e041359. PMID 33033101 DOI: 10.1136/bmjopen-2020-041359  0.424
2020 Isnard S, Lin J, Fombuena B, Ouyang J, Varin TV, Richard C, Marette A, Ramendra R, Planas D, Raymond Marchand L, Messaoudene M, Van der Ley CP, Kema IP, Sohail Ahmed D, Zhang Y, ... ... Angel J, et al. Repurposing Metformin in Nondiabetic People With HIV: Influence on Weight and Gut Microbiota. Open Forum Infectious Diseases. 7: ofaa338. PMID 32964062 DOI: 10.1093/Ofid/Ofaa338  0.413
2020 Côté SC, Schinkel SCB, Berthoud TK, Barros PO, Sanchez-Vidales M, Davidson AM, Crawley AM, Angel JB. IL-7 induces sCD127 release and mCD127 downregulation in human CD8 T cells by distinct yet overlapping mechanisms, both of which are impaired in HIV infection. European Journal of Immunology. PMID 32390135 DOI: 10.1002/eji.201948453  0.462
2020 Isnard S, Lin J, Frombuena B, Varin TV, Marette A, Planas D, Messaoudene M, Routy B, Ley CVD, Kema I, Ancuta P, Angel J, Routy J. Abstract PR04: Potential of metformin to modify the gut microbiota and prevent inflammation in nondiabetic people with HIV Cancer Research. 80. DOI: 10.1158/1538-7445.Mvc2020-Pr04  0.366
2019 Young CD, Tatieng S, Kongmanas K, Fongmoon D, Lomenick B, Yoon AJ, Kiattiburut W, Compostella F, Faull KF, Suree N, Angel JB, Tanphaichitr N. Sperm can act as vectors for HIV-1 transmission into vaginal and cervical epithelial cells. American Journal of Reproductive Immunology (New York, N.Y. : 1989). e13129. PMID 31066971 DOI: 10.1111/Aji.13129  0.66
2019 Routy JP, Isnard S, Mehraj V, Ostrowski M, Chomont N, Ancuta P, Ponte R, Planas D, Dupuy FP, Angel JB. Effect of metformin on the size of the HIV reservoir in non-diabetic ART-treated individuals: single-arm non-randomised Lilac pilot study protocol. Bmj Open. 9: e028444. PMID 31005944 DOI: 10.1136/Bmjopen-2018-028444  0.471
2019 Côté SC, Stilla A, Burke Schinkel SC, Berthoud TK, Angel JB. IL-7-induced proliferation of peripheral Th17 cells is impaired in HAART-controlled HIV infection. Aids (London, England). 33: 985-991. PMID 30946152 DOI: 10.1097/QAD.0000000000002164  0.519
2019 Giguère P, Nhean S, Tseng AL, Hughes CA, Angel JB. Getting to the Heart of the Matter: A Review of Drug Interactions Between HIV Antiretrovirals and Cardiology Medications. The Canadian Journal of Cardiology. 35: 326-340. PMID 30825953 DOI: 10.1016/j.cjca.2018.12.020  0.348
2019 Sandstrom TS, Burke Schinkel SC, Angel JB. Medical Assistance in Death as a Unique Opportunity to Advance HIV Cure Research. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 30715211 DOI: 10.1093/cid/ciz068  0.374
2018 Sandstrom TS, Angel JB. Introduction to the Special Issue: HIV Evasion of the Antiviral Response. Cytokine & Growth Factor Reviews. 40: 1-2. PMID 29778136 DOI: 10.1016/j.cytogfr.2018.03.011  0.409
2018 Busca A, Konarski Y, Gajanayaka N, O'Hara S, Angel J, Kozlowski M, Kumar A. cIAP1/2-TRAF2-SHP-1-Src-MyD88 Complex Regulates Lipopolysaccharide-Induced IL-27 Production through NF-κB Activation in Human Macrophages. Journal of Immunology (Baltimore, Md. : 1950). PMID 29358273 DOI: 10.4049/Jimmunol.1700199  0.37
2017 Ranganath N, Sandstrom TS, Burke Schinkel SC, Côté SC, Angel JB. The oncolytic virus, MG1, targets and eliminates latently HIV-1-infected cells: implications for an HIV cure. The Journal of Infectious Diseases. PMID 29228368 DOI: 10.1093/infdis/jix639  0.499
2017 Fernandes JR, Berthoud TK, Kumar A, Angel JB. IL-23 signaling in Th17 cells is inhibited by HIV infection and is not restored by HAART: Implications for persistent immune activation. Plos One. 12: e0186823. PMID 29091911 DOI: 10.1371/journal.pone.0186823  0.499
2017 Margolis DA, Gonzalez-Garcia J, Stellbrink HJ, Eron JJ, Yazdanpanah Y, Podzamczer D, Lutz T, Angel JB, Richmond GJ, Clotet B, Gutierrez F, Sloan L, Clair MS, Murray M, Ford SL, et al. Long-acting intramuscular cabotegravir and rilpivirine in adults with HIV-1 infection (LATTE-2): 96-week results of a randomised, open-label, phase 2b, non-inferiority trial. Lancet (London, England). PMID 28750935 DOI: 10.1016/S0140-6736(17)31917-7  0.385
2017 Gajanayaka N, O'Hara S, Konarski Y, Fernandes J, Muthumani K, Kozlowski M, Angel JB, Kumar A. HIV and HIV-Tat inhibit LPS-induced IL-27 production in human macrophages by distinct intracellular signaling pathways. Journal of Leukocyte Biology. PMID 28698313 DOI: 10.1189/jlb.4A0716-332RR  0.486
2017 Kennedy VL, Collins M, Yudin MH, Serghides L, Walmsley S, Angel JB, Ongoiba F, Powis J, Smaill F, Tharao W, Rachlis A, Silverman M, Sandre R, Regier DA, Loutfy M. Exploring the Factors Considered by People Living with HIV and Their Partners during Preconception. Journal of the International Association of Providers of Aids Care. 16: 239-246. PMID 28485707 DOI: 10.1177/2325957416682089  0.428
2017 Sandstrom TS, Ranganath N, Angel JB. Impairment of the type I interferon response by HIV-1: Potential targets for HIV eradication. Cytokine & Growth Factor Reviews. PMID 28455216 DOI: 10.1016/j.cytogfr.2017.04.004  0.46
2016 Ranganath N, Sandstrom TS, Fadel S, Côté SC, Angel JB. Type I interferon responses are impaired in latently HIV infected cells. Retrovirology. 13: 66. PMID 27613235 DOI: 10.1186/s12977-016-0302-9  0.492
2016 Balfour L, Wiebe SA, Cameron WD, Sandre D, Pipe A, Cooper C, Angel J, Garber G, Holly C, Dalgleish TL, Tasca GA, MacPherson PA. An HIV-tailored quit-smoking counselling pilot intervention targeting depressive symptoms plus Nicotine Replacement Therapy. Aids Care. 1-8. PMID 27435835 DOI: 10.1080/09540121.2016.1201195  0.307
2016 Graziani GM, Angel JB. HIV-1 Immunogen: an overview of almost 30 years of clinical testing of a candidate therapeutic vaccine. Expert Opinion On Biological Therapy. 16: 953-66. PMID 27266543 DOI: 10.1080/14712598.2016.1193594  0.441
2016 Jacobson JM, Routy JP, Welles S, DeBenedette M, Tcherepanova I, Angel JB, Asmuth DM, Stein DK, Baril JG, McKellar M, Margolis DM, Trottier B, Wood K, Nicolette C. Dendritic Cell Immunotherapy for HIV-1 Infection Using Autologous HIV-1 RNA: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 26751016 DOI: 10.1097/QAI.0000000000000926  0.387
2015 Graziani GM, Angel JB. Evaluating the efficacy of therapeutic HIV vaccines through analytical treatment interruptions. Journal of the International Aids Society. 18: 20497. PMID 26561337  0.31
2015 Angel JB, Routy JP, Graziani GM, Tremblay CL. The Effect of Therapeutic HIV Vaccination With ALVAC-HIV With or Without Remune on the Size of the Viral Reservoir (A CTN 173 Substudy). Journal of Acquired Immune Deficiency Syndromes (1999). 70: 122-8. PMID 26375464 DOI: 10.1097/QAI.0000000000000734  0.39
2015 Côté S, Matte J, Sad S, Angel JB, Crawley AM. Complexed soluble IL-7 receptor α and IL-7 increase IL-7-mediated proliferation and viability of CD8⁺ T-cells in vitro. Cellular Immunology. 293: 122-5. PMID 25596474 DOI: 10.1016/J.Cellimm.2015.01.001  0.305
2014 Routy JP, Angel JB, Patel M, Kanagaratham C, Radzioch D, Kema I, Gilmore N, Ancuta P, Singer J, Jenabian MA. Assessment of chloroquine as a modulator of immune activation to improve CD4 recovery in immune nonresponding HIV-infected patients receiving antiretroviral therapy. Hiv Medicine. 16: 48-56. PMID 24889179 DOI: 10.1111/hiv.12171  0.382
2014 Baril J, Conway B, Giguère P, Ferko N, Hollmann S, Angel JB. A meta-analysis of the efficacy and safety of unboosted atazanavir compared with ritonavir-boosted protease inhibitor maintenance therapy in HIV-infected adults with established virological suppression after induction. Hiv Medicine. 15: 301-10. PMID 24314017 DOI: 10.1111/Hiv.12118  0.37
2014 Crawley AM, Vranjkovic A, Faller E, McGuinty M, Busca A, Burke SC, Cousineau S, Kumar A, Macpherson PA, Angel JB. Jak/STAT and PI3K signaling pathways have both common and distinct roles in IL-7-mediated activities in human CD8+ T cells. Journal of Leukocyte Biology. 95: 117-27. PMID 24072878 DOI: 10.1189/jlb.0313122  0.323
2014 Loutfy MR, Blitz S, Zhang Y, Hart TA, Walmsley SL, Smaill FM, Rachlis AR, Yudin MH, Angel JB, Ralph ED, Tharao W, Raboud JM. Self-Reported Preconception Care of HIV-Positive Women of Reproductive Potential: A Retrospective Study. Journal of the International Association of Providers of Aids Care. 13: 424-33. PMID 23918921 DOI: 10.1177/2325957413494238  0.326
2013 Brooks JI, Niznick H, Ofner M, Merks H, Angel JB. Local phylogenetic analysis identifies distinct trends in transmitted HIV drug resistance: implications for public health interventions. Bmc Infectious Diseases. 13: 509. PMID 24171696 DOI: 10.1186/1471-2334-13-509  0.323
2013 Loutfy MR, Walmsley SL, Klein MB, Raboud J, Tseng AL, Blitz SL, Pick N, Conway B, Angel JB, Rachlis AR, Gough K, Cohen J, Haase D, Burdge D, Smaill FM, et al. Factors affecting antiretroviral pharmacokinetics in HIV-infected women with virologic suppression on combination antiretroviral therapy: a cross-sectional study. Bmc Infectious Diseases. 13: 256. PMID 23732043 DOI: 10.1186/1471-2334-13-256  0.308
2013 Costiniuk CT, Hibbert BM, Simard T, Ghazawi FM, Angel JB, O'Brien ER. Circulating endothelial progenitor cells in HIV infection: a systematic review. Trends in Cardiovascular Medicine. 23: 192-200. PMID 23395428 DOI: 10.1016/j.tcm.2012.12.002  0.441
2013 Costiniuk CT, Kovacs C, Routy JP, Singer J, Gurunathan S, Sekaly RP, Angel JB. Short communication: human immunodeficiency virus rebound in blood and seminal plasma following discontinuation of antiretroviral therapy. Aids Research and Human Retroviruses. 29: 266-9. PMID 22908887 DOI: 10.1089/Aid.2011.0343  0.377
2012 Routy JP, Angel JB, Spaans JN, Trottier B, Rouleau D, Baril JG, Harris M, Trottier S, Singer J, Chomont N, Sékaly RP, Tremblay CL. Design and implementation of a randomized crossover study of valproic acid and antiretroviral therapy to reduce the HIV reservoir. Hiv Clinical Trials. 13: 301-7. PMID 23195668 DOI: 10.1310/hct1306-301  0.461
2012 Costiniuk CT, La Porte CJ, Angel JB. Surreptitious antiretroviral use as an explanation for apparent elite HIV control. Aids Patient Care and Stds. 26: 645-6. PMID 23003207 DOI: 10.1089/apc.2012.0190  0.41
2012 Fairman P, Angel JB. The effect of human immunodeficiency virus-1 on monocyte-derived dendritic cell maturation and function. Clinical and Experimental Immunology. 170: 101-13. PMID 22943206 DOI: 10.1111/j.1365-2249.2012.04628.x  0.751
2012 Costiniuk CT, Angel JB. Human immunodeficiency virus and the gastrointestinal immune system: does highly active antiretroviral therapy restore gut immunity? Mucosal Immunology. 5: 596-604. PMID 22929559 DOI: 10.1038/mi.2012.82  0.404
2012 Crawley AM, Angel JB. The influence of HIV on CD127 expression and its potential implications for IL-7 therapy. Seminars in Immunology. 24: 231-40. PMID 22421574 DOI: 10.1016/j.smim.2012.02.006  0.487
2012 Ma W, Mishra S, Gajanayaka N, Angel JB, Kumar A. HIV-1 Nef inhibits lipopolysaccharide-induced IL-12p40 expression by inhibiting JNK-activated NFκB in human monocytic cells. The Journal of Biological Chemistry. 287: 804. PMID 22319784 DOI: 10.1074/jbc.A111.710013  0.458
2012 Routy JP, Tremblay CL, Angel JB, Trottier B, Rouleau D, Baril JG, Harris M, Trottier S, Singer J, Chomont N, Sékaly RP, Boulassel MR. Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV-1 reservoirs: results from a multicentre randomized clinical study. Hiv Medicine. 13: 291-6. PMID 22276680 DOI: 10.1111/j.1468-1293.2011.00975.x  0.42
2012 Costiniuk CT, Hibbert BM, Filion LG, Kovacs CM, Benko E, O'Brien ER, Angel JB. Circulating endothelial progenitor cell levels are not reduced in HIV-infected men. The Journal of Infectious Diseases. 205: 713-7. PMID 22238473 DOI: 10.1093/infdis/jir836  0.454
2012 Cowan J, Pandey S, Filion LG, Angel JB, Kumar A, Cameron DW. Comparison of interferon-γ-, interleukin (IL)-17- and IL-22-expressing CD4 T cells, IL-22-expressing granulocytes and proinflammatory cytokines during latent and active tuberculosis infection. Clinical and Experimental Immunology. 167: 317-29. PMID 22236009 DOI: 10.1111/j.1365-2249.2011.04520.x  0.323
2012 Loutfy M, Raboud J, Wong J, Yudin M, Diong C, Blitz S, Margolese S, Hart T, Ogilvie G, Masinde K, Tharao W, Linklater G, Salam K, Ongoiba F, Angel J, et al. High prevalence of unintended pregnancies in HIV-positive women of reproductive age in Ontario, Canada: a retrospective study. Hiv Medicine. 13: 107-17. PMID 22103297 DOI: 10.1111/J.1468-1293.2011.00946.X  0.391
2012 Crawley AM, Angel JB. Expression of γ-chain cytokine receptors on CD8+ T cells in HIV infection with a focus on IL-7Rα (CD127). Immunology and Cell Biology. 90: 379-87. PMID 21863001 DOI: 10.1038/icb.2011.66  0.504
2012 Vranjkovic A, Crawley AM, Angel JB. In vitro HIV Type 1 infection indirectly alters CD127 expression on CD8(+) T cells. Aids Research and Human Retroviruses. 28: 295-8. PMID 21740271 DOI: 10.1089/aid.2011.0003  0.458
2012 Tulloch HE, Balfour L, Kowal J, Tasca GA, Angel JB, Garber G, Macpherson P, Cooper C, Cameron DW. HIV knowledge among Canadian-born and sub-Saharan African-born patients living with HIV. Journal of Immigrant and Minority Health / Center For Minority Public Health. 14: 132-9. PMID 21643728 DOI: 10.1007/s10903-011-9480-7  0.412
2012 Gee K, Angel JB, Mishra S, Blahoianu MA, Kumar A. IL-10 regulation by HIV-Tat in primary human monocytic cells: Involvement of calmodulin/calmodulin-dependent protein kinase-activated p38 MAPK and Sp-1 and CREB-1 transcription factors (Journal of Immunology (2007) 178, (798-807)) Journal of Immunology. 188: 3553. DOI: 10.4049/jimmunol.1290011  0.417
2012 Costiniuk CT, Hibbert BM, Filion LG, O'Brien ER, Angel JB. Reply to: Cardiovascular disease risk in HIV infection and endothelial progenitor cells Journal of Infectious Diseases. 206: 1480-1481. DOI: 10.1093/infdis/jis519  0.37
2012 Young C, Fongmoon D, Kongmanas K, Faull K, Angel J, Tanphaichitr N. Sperm May Act as a Vector for HIV Transmission to the Genital Epithelium. Biology of Reproduction. 87: 451-451. DOI: 10.1093/Biolreprod/87.S1.451  0.67
2011 Costiniuk CT, Fergusson DA, Doucette S, Angel JB. Discontinuation of Pneumocystis jirovecii pneumonia prophylaxis with CD4 count <200 cells/µL and virologic suppression: a systematic review. Plos One. 6: e28570. PMID 22194853 DOI: 10.1371/Journal.Pone.0028570  0.367
2011 Young CD, Angel JB. HIV infection of thymocytes inhibits IL-7 activity without altering CD127 expression. Retrovirology. 8: 72. PMID 21920046 DOI: 10.1186/1742-4690-8-72  0.691
2011 Angel JB, Routy JP, Tremblay C, Ayers D, Woods R, Singer J, Bernard N, Kovacs C, Smaill F, Gurunathan S, Sekaly RP. A randomized controlled trial of HIV therapeutic vaccination using ALVAC with or without Remune. Aids (London, England). 25: 731-9. PMID 21330911 DOI: 10.1097/Qad.0B013E328344Cea5  0.425
2011 Vranjkovic A, Crawley AM, Patey A, Angel JB. IL-7-dependent STAT-5 activation and CD8+ T cell proliferation are impaired in HIV infection. Journal of Leukocyte Biology. 89: 499-506. PMID 21177484 DOI: 10.1189/jlb.0710430  0.494
2010 Leece P, Kendall C, Touchie C, Pottie K, Angel JB, Jaffey J. Cervical cancer screening among HIV-positive women. Retrospective cohort study from a tertiary care HIV clinic. Canadian Family Physician MéDecin De Famille Canadien. 56: e425-31. PMID 21375064  0.35
2010 Natesampillai S, Nie Z, Cummins NW, Jochmans D, Bren GD, Angel JB, Badley AD. Patients with discordant responses to antiretroviral therapy have impaired killing of HIV-infected T cells. Plos Pathogens. 6: e1001213. PMID 21124822 DOI: 10.1371/journal.ppat.1001213  0.496
2010 O'Connor AM, Crawley AM, Angel JB. Interleukin-7 enhances memory CD8(+) T-cell recall responses in health but its activity is impaired in human immunodeficiency virus infection. Immunology. 131: 525-36. PMID 20673240 DOI: 10.1111/j.1365-2567.2010.03325.x  0.428
2010 Crawley AM, Faucher S, Angel JB. Soluble IL-7R alpha (sCD127) inhibits IL-7 activity and is increased in HIV infection. Journal of Immunology (Baltimore, Md. : 1950). 184: 4679-87. PMID 20304824 DOI: 10.4049/jimmunol.0903758  0.471
2010 Crawley AM, Vranjkovic A, Young C, Angel JB. Interleukin-4 downregulates CD127 expression and activity on human thymocytes and mature CD8+ T cells. European Journal of Immunology. 40: 1396-407. PMID 20201040 DOI: 10.1002/eji.200940093  0.608
2010 Boucher JG, Parato KA, Frappier F, Fairman P, Busca A, Saxena M, Blahoianu MA, Ma W, Gajanayaka N, Parks RJ, Kumar A, Angel JB. Disparate regulation of LPS-induced MAPK signaling and IL-12p40 expression between different myeloid cell types with and without HIV infection. Viral Immunology. 23: 17-28. PMID 20121399 DOI: 10.1089/Vim.2009.0054  0.739
2009 Rachlis A, Angel JB, Harris M, Shafran SD, Therrien R, Tremblay C, Wainberg MA. Optimal use of raltegravir (Isentress(R)) in the treatment of HIV-infected adults - Canadian consensus guidelines. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie MéDicale / Ammi Canada. 20: e67-80. PMID 20808458 DOI: 10.1155/2009/940745  0.374
2009 Harris M, Angel JB, Baril JG, Rachlis A, Trottier B. Canadian consensus guidelines for the optimal use of etravirine in the treatment of HIV-infected adults. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie MéDicale / Ammi Canada. 20: e24-34. PMID 20514155  0.437
2009 Loutfy MR, Hart TA, Mohammed SS, Su D, Ralph ED, Walmsley SL, Soje LC, Muchenje M, Rachlis AR, Smaill FM, Angel JB, Raboud JM, Silverman MS, Tharao WE, Gough K, et al. Fertility desires and intentions of HIV-positive women of reproductive age in Ontario, Canada: a cross-sectional study. Plos One. 4: e7925. PMID 19997556 DOI: 10.1371/Journal.Pone.0007925  0.319
2009 Angel JB, Greaves W, Long J, Ward D, Rodriguez AE, Scevola D, DeJesus E. Virologic and immunologic activity of PegIntron in HIV disease. Aids (London, England). 23: 2431-8. PMID 19898218 DOI: 10.1097/QAD.0b013e32832f30ca  0.399
2009 Faucher S, Crawley AM, Decker W, Sherring A, Bogdanovic D, Ding T, Bergeron M, Angel JB, Sandstrom P. Development of a quantitative bead capture assay for soluble IL-7 receptor alpha in human plasma. Plos One. 4: e6690. PMID 19690616 DOI: 10.1371/journal.pone.0006690  0.341
2009 Ma W, Mishra S, Gajanayaka N, Angel JB, Kumar A. HIV-1 Nef inhibits lipopolysaccharide-induced IL-12p40 expression by inhibiting JNK-activated NFkappaB in human monocytic cells. The Journal of Biological Chemistry. 284: 7578-87. PMID 19019824 DOI: 10.1074/jbc.M710013200  0.427
2008 Landovitz RJ, Angel JB, Hoffmann C, Horst H, Opravil M, Long J, Greaves W, Fätkenheuer G. Phase II study of vicriviroc versus efavirenz (both with zidovudine/lamivudine) in treatment-naive subjects with HIV-1 infection. The Journal of Infectious Diseases. 198: 1113-22. PMID 18783318 DOI: 10.1086/592052  0.416
2008 Angel JB, Cooper CL, Clinch J, Young CD, Chenier A, Parato KG, Lautru M, Davis H, Cameron DW. CpG increases vaccine antigen-specific cell-mediated immunity when administered with hepatitis B vaccine in HIV infection. Journal of Immune Based Therapies and Vaccines. 6: 4. PMID 18700037 DOI: 10.1186/1476-8518-6-4  0.533
2008 Shepard BD, Loutfy MR, Raboud J, Mandy F, Kovacs CM, Diong C, Bergeron M, Govan V, Rizza SA, Angel JB, Badley AD. Early changes in T-cell activation predict antiretroviral success in salvage therapy of HIV infection. Journal of Acquired Immune Deficiency Syndromes (1999). 48: 149-55. PMID 18360289 DOI: 10.1097/QAI.0b013e31816d9c3b  0.329
2007 Balfour L, Kowal J, Tasca GA, Cooper CL, Angel JB, Macpherson PA, Garber G, Béïque L, Cameron DW. Development and psychometric validation of the HIV Treatment Knowledge Scale. Aids Care. 19: 1141-8. PMID 18058398 DOI: 10.1080/09540120701352241  0.39
2007 Balfour L, Tasca GA, Kowal J, Corace K, Cooper CL, Angel JB, Garber G, Macpherson PA, Cameron DW. Development and validation of the HIV Medication Readiness Scale. Assessment. 14: 408-16. PMID 17986658 DOI: 10.1177/1073191107304295  0.377
2007 Vranjkovic A, Crawley AM, Gee K, Kumar A, Angel JB. IL-7 decreases IL-7 receptor alpha (CD127) expression and induces the shedding of CD127 by human CD8+ T cells. International Immunology. 19: 1329-39. PMID 17956896 DOI: 10.1093/intimm/dxm102  0.389
2007 Pott GB, Sailer CA, Porat R, Peskind RL, Fuchs AC, Angel JB, Skolnik PR, Jacobson MA, Giordano MF, Lebeaut A, Grint PC, Dinarello CA, Shapiro L. Effect of a four-week course of interleukin-10 on cytokine production in a placebo-controlled study of HIV-1-infected subjects. European Cytokine Network. 18: 49-58. PMID 17594937 DOI: 10.1684/Ecn.2007.0094  0.355
2007 Gee K, Angel JB, Mishra S, Blahoianu MA, Kumar A. IL-10 regulation by HIV-Tat in primary human monocytic cells: involvement of calmodulin/calmodulin-dependent protein kinase-activated p38 MAPK and Sp-1 and CREB-1 transcription factors. Journal of Immunology (Baltimore, Md. : 1950). 178: 798-807. PMID 17202341  0.46
2007 Cooper CL, Mills E, Angel JB. Mitigation of antiretroviral-induced hyperlipidemia by hepatitis C virus co-infection. Aids (London, England). 21: 71-6. PMID 17148970 DOI: 10.1097/QAD.0b013e3280110ada  0.347
2006 Rachlis A, Angel J, Harris M, Lalonde R, Smaill F, Tremblay C, Tsoukas C, Walmsley S. Canadian Consensus Recommendations for the Optimal Use of Enfuvirtide in HIV/AIDS Patients. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie MéDicale / Ammi Canada. 17: 155-63. PMID 18418493 DOI: 10.1155/2006/402409  0.488
2006 Creery D, Weiss W, Graziani-Bowering G, Kumar R, Aziz Z, Angel JB, Kumar A. Differential regulation of CXCR4 and CCR5 expression by interleukin (IL)-4 and IL-13 is associated with inhibition of chemotaxis and human immunodeficiency Virus (HIV) type 1 replication but not HIV entry into human monocytes. Viral Immunology. 19: 409-23. PMID 16987060 DOI: 10.1089/vim.2006.19.409  0.437
2006 Beaudoin G, Diker B, Angel JB, Copeland KF. Effects of highly active antiretroviral therapy and immune recovery on CD8+ T-cell-mediated inhibition of HIV-1 transcription. Journal of Acquired Immune Deficiency Syndromes (1999). 43: 393-400. PMID 16967042 DOI: 10.1097/01.qai.0000232916.35884.7b  0.43
2006 Gee K, Angel JB, Ma W, Mishra S, Gajanayaka N, Parato K, Kumar A. Intracellular HIV-Tat expression induces IL-10 synthesis by the CREB-1 transcription factor through Ser133 phosphorylation and its regulation by the ERK1/2 MAPK in human monocytic cells. The Journal of Biological Chemistry. 281: 31647-58. PMID 16920714 DOI: 10.1074/jbc.M512109200  0.452
2006 Young CD, Angel JB. Optimization of culture and storage conditions for an in vitro system to evaluate thymocyte phenotype and function. Journal of Immunological Methods. 312: 157-66. PMID 16647713 DOI: 10.1016/J.Jim.2006.03.001  0.579
2006 Walmsley SL, Raboud J, Angel JB, Mazzulli T, Shen S, Casciaro L, Young CD, Moussa G, Gough K, Rachlis A, Hopkins J. Long-term follow-up of a cohort of HIV-infected patients who discontinued maintenance therapy for cytomegalovirus retinitis. Hiv Clinical Trials. 7: 1-9. PMID 16632459 DOI: 10.1310/9M23-Qn0X-W6N8-80Jd  0.563
2005 Karsh J, Angel JB, Young CD, Sahni V, Judek S, Miller D, Dales RE. Association of the frequency of respiratory illness in early childhood with a change in the distribution of blood lymphocyte subpopulations. Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology. 1: 135-41. PMID 20529218 DOI: 10.1186/1710-1492-1-4-135  0.508
2005 Cooper CL, Davis HL, Angel JB, Morris ML, Elfer SM, Seguin I, Krieg AM, Cameron DW. CPG 7909 adjuvant improves hepatitis B virus vaccine seroprotection in antiretroviral-treated HIV-infected adults. Aids (London, England). 19: 1473-9. PMID 16135900  0.357
2005 Brown PA, Angel JB. Granulocyte-macrophage colony-stimulating factor as an immune-based therapy in HIV infection. Journal of Immune Based Therapies and Vaccines. 3: 3. PMID 15904525 DOI: 10.1186/1476-8518-3-3  0.427
2004 Chambers KA, Parks RJ, Angel JB. Disruption of MAP kinase activation and nuclear factor binding to the IL-12 p40 promoter in HIV-infected myeloid cells. Clinical and Experimental Immunology. 137: 329-40. PMID 15270850 DOI: 10.1111/J.1365-2249.2004.02513.X  0.755
2004 Creery D, Weiss W, Lim WT, Aziz Z, Angel JB, Kumar A. Down-regulation of CXCR-4 and CCR-5 expression by interferon-gamma is associated with inhibition of chemotaxis and human immunodeficiency virus (HIV) replication but not HIV entry into human monocytes. Clinical and Experimental Immunology. 137: 156-65. PMID 15196257 DOI: 10.1111/j.1365-2249.2004.02495.x  0.439
2004 Angel JB, Hu YW, Kravcik S, Tsui R, Lee KH, Barbour J, Balaskas E, Branson BM, Delwart EL, Grant RM. Virological evaluation of the 'Ottawa case' indicates no evidence for HIV-1 superinfection. Aids (London, England). 18: 331-4. PMID 15075555  0.416
2004 Cooper CL, Phenix B, Mbisa G, Lum JJ, Parato K, Hawley N, Angel JB, Badley AD. Antiretroviral therapy influences cellular susceptibility to apoptosis in vivo. Frontiers in Bioscience : a Journal and Virtual Library. 9: 338-41. PMID 14766370 DOI: 10.2741/1230  0.461
2002 Creery D, Angel JB, Aucoin S, Weiss W, Cameron WD, Diaz-Mitoma F, Kumar A. Nef protein of human immunodeficiency virus and lipopolysaccharide induce expression of CD14 on human monocytes through differential utilization of interleukin-10. Clinical and Diagnostic Laboratory Immunology. 9: 1212-21. PMID 12414752 DOI: 10.1128/Cdli.9.6.1212-1221.2002  0.508
2002 Chambers KA, Parato KG, Angel JB. Active cellular infection of myeloid cells is required for HIV-1-mediated suppression of interleukin-12 p40 expression. Cellular Immunology. 215: 120-32. PMID 12202149 DOI: 10.1016/S0008-8749(02)00020-5  0.766
2002 Parato KG, Kumar A, Badley AD, Sanchez-Dardon JL, Chambers KA, Young CD, Lim WT, Kravcik S, Cameron DW, Angel JB. Normalization of natural killer cell function and phenotype with effective anti-HIV therapy and the role of IL-10. Aids (London, England). 16: 1251-6. PMID 12045490 DOI: 10.1097/00002030-200206140-00007  0.765
2002 MacPherson PA, Fex C, Sanchez-Dardon J, Hawley-Foss N, Angel JB. Interleukin-7 receptor expression on CD8(+) T cells is reduced in HIV infection and partially restored with effective antiretroviral therapy. Journal of Acquired Immune Deficiency Syndromes (1999). 28: 454-7. PMID 11744834 DOI: 10.1097/00042560-200112150-00008  0.483
2001 Cooper CL, Badley AD, Angel JB. Characteristics of hepatitis C virus infection in HIV-infected people. The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses. 12: 157-63. PMID 18159334 DOI: 10.1155/2001/542056  0.343
2001 Angel JB. Improving immune function and controlling viral replication in HIV-1-infected patients with immune-based therapies Aids Reader. 11: 209-215+217. PMID 11392678  0.41
2001 Angel JB, Khaliq Y, Monpetit ML, Cameron DW, Gallicano K. An argument for routine therapeutic drug monitoring of HIV-1 protease inhibitors during pregnancy. Aids (London, England). 15: 417-9. PMID 11273224 DOI: 10.1097/00002030-200102160-00017  0.314
2001 Angel JB, Parato KG, Kumar A, Kravcik S, Badley AD, Fex C, Ashby D, Sun E, Cameron DW. Progressive human immunodeficiency virus-specific immune recovery with prolonged viral suppression. The Journal of Infectious Diseases. 183: 546-54. PMID 11170979 DOI: 10.1086/318547  0.414
2000 Angel JB, Jacobson MA, Skolnik PR, Giordano M, Shapiro L, LeBeaut A, Greaves W, Fuchs AC. A multicenter, randomized, double-blind, placebo-controlled trial of recombinant human interleukin-10 in HIV-infected subjects. Aids (London, England). 14: 2503-8. PMID 11101061 DOI: 10.1097/00002030-200011100-00012  0.448
2000 Phenix BN, Angel JB, Mandy F, Kravcik S, Parato K, Chambers KA, Gallicano K, Hawley-Foss N, Cassol S, Cameron DW, Badley AD. Decreased HIV-associated T cell apoptosis by HIV protease inhibitors. Aids Research and Human Retroviruses. 16: 559-67. PMID 10777146 DOI: 10.1089/088922200308972  0.747
2000 Angel JB, High K, Rhame F, Brand D, Whitmore JB, Agosti JM, Gilbert MJ, Deresinski S. Phase III study of granulocyte-macrophage colony-stimulating factor in advanced HIV disease: effect on infections, CD4 cell counts and HIV suppression. Leukine/HIV Study Group. Aids (London, England). 14: 387-95. PMID 10770541 DOI: 10.1097/00002030-200003100-00012  0.479
1999 Kumar D, Parato K, Kumar A, Sun E, Cameron DW, Angel JB. Sustained suppression of plasma HIV RNA is associated with an increase in the production of mitogen-induced MIP-1alpha and MIP-1beta. Aids Research and Human Retroviruses. 15: 1073-7. PMID 10461827 DOI: 10.1089/088922299310368  0.364
1999 Badley AD, Parato K, Cameron DW, Kravcik S, Phenix BN, Ashby D, Kumar A, Lynch DH, Tschopp J, Angel JB. Dynamic correlation of apoptosis and immune activation during treatment of HIV infection. Cell Death and Differentiation. 6: 420-32. PMID 10381636 DOI: 10.1038/Sj.Cdd.4400509  0.476
1999 Cameron DW, Japour AJ, Xu Y, Hsu A, Mellors J, Farthing C, Cohen C, Poretz D, Markowitz M, Follansbee S, Angel JB, McMahon D, Ho D, Devanarayan V, Rode R, et al. Ritonavir and saquinavir combination therapy for the treatment of HIV infection. Aids (London, England). 13: 213-24. PMID 10202827 DOI: 10.1097/00002030-199902040-00009  0.439
1999 Chan J, Kravcik S, Angel JB. Development of Kaposi's Sarcoma Despite Sustained Suppression of HIV Plasma Viremia Journal of Acquired Immune Deficiency Syndromes. 22: 209. DOI: 10.1097/00042560-199910010-00017  0.358
1998 Kravcik S, Victor G, Houston S, Sutherland D, Garber GE, Hawley-Foss N, Angel JB, Cameron DW. Effect of antiretroviral therapy and viral load on the perceived risk of HIV transmission and the need for safer sexual practices. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 19: 124-9. PMID 9768620 DOI: 10.1097/00042560-199810010-00004  0.375
1998 Kumar A, Angel JB, Daftarian MP, Parato K, Cameron WD, Filion L, Diaz-Mitoma F. Differential production of IL-10 by T cells and monocytes of HIV- infected individuals: Association of IL-10 production with CD28-mediated immune responsiveness Clinical and Experimental Immunology. 114: 78-86. PMID 9764607 DOI: 10.1046/J.1365-2249.1998.00689.X  0.45
1998 Angel JB, Kumar A, Parato K, Filion LG, Diaz-Mitoma F, Daftarian P, Pham B, Sun E, Leonard JM, Cameron DW. Improvement in cell-mediated immune function during potent anti-human immunodeficiency virus therapy with ritonavir plus saquinavir. The Journal of Infectious Diseases. 177: 898-904. PMID 9534961 DOI: 10.1086/515244  0.433
1996 Granowitz EV, Saget BM, Angel JB, Wang MZ, Wang A, Dinarello CA, Skolnik PR. Soluble tumor necrosis factor receptors inhibit phorbol myristate acetate and cytokine-induced HIV-1 expression chronically infected U1 cells. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 11: 430-7. PMID 8605587 DOI: 10.1097/00042560-199604150-00002  0.397
1994 Angel J, Wang M, Wang A, Dinarello C, Skolnik P. Interleukin-10 enhances HIV-1 expression in a chronically infected promonocytic cell line (U1) by a TNFα-independent mechanism Cytokine. 6: 567. DOI: 10.1016/1043-4666(94)90249-6  0.439
1993 Angel JB, Hussey EK, Hall ST, Donn KH, Morris DM, McCormack JP, Montaner JSG, Ruedy J. Pharmacokinetics of 3TC (GR109714X) administered with and without food to HIV-infected patients Drug Investigation. 6: 70-74. DOI: 10.1007/BF03258455  0.387
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