Year |
Citation |
Score |
2020 |
Zimmer BM, Barycki JJ, Simpson MA. Integration of Sugar Metabolism and Proteoglycan Synthesis by UDP-glucose Dehydrogenase. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 22155420947500. PMID 32749901 DOI: 10.1369/0022155420947500 |
0.312 |
|
2019 |
Nowialis P, Lopusna K, Opavska J, Haney SL, Abraham A, Sheng P, Riva A, Natarajan A, Guryanova O, Simpson M, Hlady R, Xie M, Opavsky R. Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions. Nature Communications. 10: 4374. PMID 31558711 DOI: 10.1038/S41467-019-12355-7 |
0.332 |
|
2018 |
Monks A, Zhao Y, Hose C, Hamed H, Krushkal J, Fang J, Sonkin D, Palmisano A, Polley EC, Fogli LK, Konaté MM, Miller SB, Simpson MA, Voth AR, Li MC, et al. The NCI Transcriptional Pharmacodynamics Workbench: a tool to examine dynamic expression profiling of therapeutic response in the NCI-60 cell line panel. Cancer Research. PMID 30355619 DOI: 10.1158/0008-5472.Can-18-0989 |
0.321 |
|
2018 |
McAtee CO, Booth C, Elowsky C, Zhao L, Payne J, Fangman T, Caplan S, Henry MD, Simpson MA. Prostate tumor cell exosomes containing hyaluronidase Hyal1 stimulate prostate stromal cell motility by engagement of FAK-mediated integrin signaling. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29753676 DOI: 10.1016/J.Matbio.2018.05.002 |
0.451 |
|
2016 |
Zimmer BM, Howell ME, Wei Q, Ma L, Romsdahl T, Loughman EG, Markham JE, Seravalli J, Barycki JJ, Simpson MA. Loss of exogenous androgen dependence by prostate tumor cells is associated with elevated glucuronidation potential. Hormones & Cancer. PMID 27307252 DOI: 10.1007/S12672-016-0268-Z |
0.456 |
|
2016 |
Grady G, Thelen AM, Albers J, Ju T, Guo J, Barycki JJ, Simpson MA. Inhibiting hexamer disassembly of UDP-glucose dehydrogenase by photoactivated amino acid crosslinking. Biochemistry. PMID 27198584 DOI: 10.1021/Acs.Biochem.6B00259 |
0.326 |
|
2016 |
Palmer M, Ma L, Romsdahl T, Wei Q, Loughman E, Markham J, Barycki J, Simpson MA. Abstract C41: Altered control of intracellular androgen availability by glucuronidation contributes to loss of androgen dependence in prostate tumor cells Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-C41 |
0.466 |
|
2015 |
McAtee CO, Berkebile AR, Elowsky CG, Fangman T, Barycki JJ, Wahl JK, Khalimonchuk O, Naslavsky N, Caplan S, Simpson MA. Hyaluronidase Hyal1 Increases Tumor Cell Proliferation and Motility through Accelerated Vesicle Trafficking. The Journal of Biological Chemistry. 290: 13144-56. PMID 25855794 DOI: 10.1074/Jbc.M115.647446 |
0.479 |
|
2015 |
Haney SL, Hlady RA, Opavska J, Klinkebiel D, Pirruccello SJ, Dutta S, Datta K, Simpson MA, Wu L, Opavsky R. Methylation-independent repression of Dnmt3b contributes to oncogenic activity of Dnmt3a in mouse MYC-induced T-cell lymphomagenesis. Oncogene. PMID 25639876 DOI: 10.1038/Onc.2014.472 |
0.357 |
|
2014 |
McAtee CO, Barycki JJ, Simpson MA. Emerging roles for hyaluronidase in cancer metastasis and therapy. Advances in Cancer Research. 123: 1-34. PMID 25081524 DOI: 10.1016/B978-0-12-800092-2.00001-0 |
0.397 |
|
2014 |
Liu Y, Hyde AS, Simpson MA, Barycki JJ. Emerging regulatory paradigms in glutathione metabolism. Advances in Cancer Research. 122: 69-101. PMID 24974179 DOI: 10.1016/B978-0-12-420117-0.00002-5 |
0.353 |
|
2014 |
Kovar JL, Cheung LL, Simpson MA, Olive DM. Pharmacokinetic and Biodistribution Assessment of a Near Infrared-Labeled PSMA-Specific Small Molecule in Tumor-Bearing Mice. Prostate Cancer. 2014: 104248. PMID 24804103 DOI: 10.1155/2014/104248 |
0.394 |
|
2014 |
Peters SL, Hlady RA, Opavska J, Klinkebiel D, Pirruccello SJ, Talmon GA, Sharp JG, Wu L, Jaenisch R, Simpson MA, Karpf AR, Opavsky R. Tumor suppressor functions of Dnmt3a and Dnmt3b in the prevention of malignant mouse lymphopoiesis. Leukemia. 28: 1138-42. PMID 24292811 DOI: 10.1038/Leu.2013.364 |
0.323 |
|
2013 |
Hyde AS, Thelen AM, Barycki JJ, Simpson MA. UDP-glucose dehydrogenase activity and optimal downstream cellular function require dynamic reorganization at the dimer-dimer subunit interfaces Journal of Biological Chemistry. 288: 35049-35057. PMID 24145036 DOI: 10.1074/Jbc.M113.519090 |
0.345 |
|
2013 |
Peters SL, Hlady RA, Opavska J, Klinkebiel D, Novakova S, Smith LM, Lewis RE, Karpf AR, Simpson MA, Wu L, Opavsky R. Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas. Molecular and Cellular Biology. 33: 4321-33. PMID 24001767 DOI: 10.1128/Mcb.00776-13 |
0.307 |
|
2013 |
Kovar JL, Curtis E, Othman SF, Simpson MA, Olive DM. Characterization of IRDye 800CW chlorotoxin as a targeting agent for brain tumors. Analytical Biochemistry. 440: 212-9. PMID 23711726 DOI: 10.1016/J.Ab.2013.05.013 |
0.325 |
|
2012 |
Natarajan SK, Zhu W, Liang X, Zhang L, Demers AJ, Zimmerman MC, Simpson MA, Becker DF. Proline dehydrogenase is essential for proline protection against hydrogen peroxide-induced cell death. Free Radical Biology & Medicine. 53: 1181-91. PMID 22796327 DOI: 10.1016/J.Freeradbiomed.2012.07.002 |
0.351 |
|
2012 |
Simpson MA, Weigel JA, Weigel PH. Systemic blockade of the hyaluronan receptor for endocytosis prevents lymph node metastasis of prostate cancer. International Journal of Cancer. Journal International Du Cancer. 131: E836-40. PMID 22234863 DOI: 10.1002/Ijc.27427 |
0.435 |
|
2012 |
Hlady RA, Novakova S, Opavska J, Klinkebiel D, Peters SL, Bies J, Hannah J, Iqbal J, Anderson KM, Siebler HM, Smith LM, Greiner TC, Bastola D, Joshi S, Lockridge O, ... Simpson MA, et al. Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis. The Journal of Clinical Investigation. 122: 163-77. PMID 22133874 DOI: 10.1172/Jci57292 |
0.368 |
|
2012 |
Kovar JL, Cheung LL, Simpson MA, Olive DM. Abstract 2433: Comparisons between an IRDye 800CW-labeled PSMA-targeted small molecule and antibody for preclinical small animal imaging Cancer Research. 72: 2433-2433. DOI: 10.1158/1538-7445.Am2012-2433 |
0.351 |
|
2011 |
Willis MN, Liu Y, Biterova EI, Simpson MA, Kim H, Lee J, Barycki JJ. Enzymatic defects underlying hereditary glutamate cysteine ligase deficiency are mitigated by association of the catalytic and regulatory subunits. Biochemistry. 50: 6508-17. PMID 21657237 DOI: 10.1021/Bi200708W |
0.313 |
|
2011 |
Bharadwaj AG, Goodrich NP, McAtee CO, Haferbier K, Oakley GG, Wahl JK, Simpson MA. Hyaluronan suppresses prostate tumor cell proliferation through diminished expression of N-cadherin and aberrant growth factor receptor signaling. Experimental Cell Research. 317: 1214-25. PMID 21315068 DOI: 10.1016/J.Yexcr.2011.01.026 |
0.743 |
|
2011 |
Kovar JL, Olive DM, Simpson MA. Abstract C44: Metastatic potential of prostate tumor cells is affected by hyaluronan metabolism. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-C44 |
0.46 |
|
2011 |
Kovar JL, Curtis E, Othman SF, Simpson MA, Olive DM. Abstract C4: Specific targeting of spontaneous medulloblastoma tumors in mice by IRDye 800CW chlorotoxin. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-C4 |
0.328 |
|
2010 |
Huang D, Casale GP, Tian J, Lele SM, Pisarev VM, Simpson MA, Hemstreet GP. Udp-glucose dehydrogenase as a novel field-specific candidate biomarker of prostate cancer. International Journal of Cancer. 126: 315-27. PMID 19676054 DOI: 10.1002/Ijc.24820 |
0.353 |
|
2010 |
Wei Q, Simpson MA. Abstract LB-200: Regulation of intracellular androgen availability by glucuronidation in prostate tumor cells may contribute to loss of circulating androgen dependence in prostate cancer Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-200 |
0.457 |
|
2009 |
Wei Q, Galbenus R, Raza A, Cerny RL, Simpson MA. Androgen-stimulated UDP-glucose dehydrogenase expression limits prostate androgen availability without impacting hyaluronan levels. Cancer Research. 69: 2332-9. PMID 19244115 DOI: 10.1158/0008-5472.Can-08-3083 |
0.467 |
|
2009 |
Bharadwaj AG, Kovar JL, Loughman E, Elowsky C, Oakley GG, Simpson MA. Spontaneous metastasis of prostate cancer is promoted by excess hyaluronan synthesis and processing. The American Journal of Pathology. 174: 1027-36. PMID 19218337 DOI: 10.2353/Ajpath.2009.080501 |
0.743 |
|
2009 |
Zhang L, Bharadwaj AG, Casper A, Barkley J, Barycki JJ, Simpson MA. Hyaluronidase activity of human Hyal1 requires active site acidic and tyrosine residues. The Journal of Biological Chemistry. 284: 9433-42. PMID 19201751 DOI: 10.1074/Jbc.M900210200 |
0.714 |
|
2009 |
Kovar JL, Volcheck W, Sevick-Muraca E, Simpson MA, Olive DM. Characterization and performance of a near-infrared 2-deoxyglucose optical imaging agent for mouse cancer models Analytical Biochemistry. 384: 254-262. PMID 18938129 DOI: 10.1016/J.Ab.2008.09.050 |
0.341 |
|
2009 |
Simpson MA. Hyaluronan Synthesis and Turnover in Prostate Cancer Hyaluronan in Cancer Biology. 309-327. DOI: 10.1016/B978-012374178-3.10016-X |
0.325 |
|
2008 |
Simpson MA, Lokeshwar VB. Hyaluronan and hyaluronidase in genitourinary tumors. Frontiers in Bioscience : a Journal and Virtual Library. 13: 5664-80. PMID 18508614 DOI: 10.2741/3108 |
0.389 |
|
2007 |
Bharadwaj AG, Rector K, Simpson MA. Inducible hyaluronan production reveals differential effects on prostate tumor cell growth and tumor angiogenesis. The Journal of Biological Chemistry. 282: 20561-72. PMID 17502371 DOI: 10.1074/Jbc.M702964200 |
0.743 |
|
2007 |
Easley KE, Sommer BJ, Boanca G, Barycki JJ, Simpson MA. Characterization of human UDP-glucose dehydrogenase reveals critical catalytic roles for lysine 220 and aspartate 280. Biochemistry. 46: 369-78. PMID 17209547 DOI: 10.1021/Bi061537D |
0.359 |
|
2007 |
Kovar JL, Volcheck WM, Chen J, Simpson MA. Purification method directly influences effectiveness of an epidermal growth factor-coupled targeting agent for noninvasive tumor detection in mice. Analytical Biochemistry. 361: 47-54. PMID 17188228 DOI: 10.1016/J.Ab.2006.11.021 |
0.361 |
|
2006 |
Kovar JL, Johnson MA, Volcheck WM, Chen J, Simpson MA. Hyaluronidase expression induces prostate tumor metastasis in an orthotopic mouse model. The American Journal of Pathology. 169: 1415-26. PMID 17003496 DOI: 10.2353/Ajpath.2006.060324 |
0.434 |
|
2006 |
Simpson MA. Concurrent expression of hyaluronan biosynthetic and processing enzymes promotes growth and vascularization of prostate tumors in mice. The American Journal of Pathology. 169: 247-57. PMID 16816377 DOI: 10.2353/Ajpath.2006.060032 |
0.489 |
|
2004 |
Kim HR, Wheeler MA, Wilson CM, Iida J, Eng D, Simpson MA, McCarthy JB, Bullard KM. Hyaluronan facilitates invasion of colon carcinoma cells in vitro via interaction with CD44. Cancer Research. 64: 4569-76. PMID 15231668 DOI: 10.1158/0008-5472.Can-04-0202 |
0.372 |
|
2004 |
Yang J, Price MA, Neudauer CL, Wilson C, Ferrone S, Xia H, Iida J, Simpson MA, McCarthy JB. Melanoma chondroitin sulfate proteoglycan enhances FAK and ERK activation by distinct mechanisms. The Journal of Cell Biology. 165: 881-91. PMID 15210734 DOI: 10.1083/Jcb.200403174 |
0.408 |
|
2004 |
Sommer BJ, Barycki JJ, Simpson MA. Characterization of human UDP-glucose dehydrogenase. CYS-276 is required for the second of two successive oxidations. The Journal of Biological Chemistry. 279: 23590-6. PMID 15044486 DOI: 10.1074/Jbc.M401928200 |
0.344 |
|
2003 |
Bullard KM, Kim HR, Wheeler MA, Wilson CM, Neudauer CL, Simpson MA, McCarthy JB. Hyaluronan synthase-3 is upregulated in metastatic colon carcinoma cells and manipulation of expression alters matrix retention and cellular growth. International Journal of Cancer. Journal International Du Cancer. 107: 739-46. PMID 14566823 DOI: 10.1002/Ijc.11475 |
0.437 |
|
2002 |
Simpson MA, Wilson CM, McCarthy JB. Inhibition of prostate tumor cell hyaluronan synthesis impairs subcutaneous growth and vascularization in immunocompromised mice. The American Journal of Pathology. 161: 849-57. PMID 12213713 DOI: 10.1016/S0002-9440(10)64245-9 |
0.485 |
|
2002 |
Simpson MA, Wilson CM, Furcht LT, Spicer AP, Oegema TR, McCarthy JB. Manipulation of hyaluronan synthase expression in prostate adenocarcinoma cells alters pericellular matrix retention and adhesion to bone marrow endothelial cells. The Journal of Biological Chemistry. 277: 10050-7. PMID 11790779 DOI: 10.1074/Jbc.M110069200 |
0.44 |
|
2001 |
Simpson MA, Reiland J, Burger SR, Furcht LT, Spicer AP, Oegema TR, McCarthy JB. Hyaluronan synthase elevation in metastatic prostate carcinoma cells correlates with hyaluronan surface retention, a prerequisite for rapid adhesion to bone marrow endothelial cells. The Journal of Biological Chemistry. 276: 17949-57. PMID 11278609 DOI: 10.1074/Jbc.M010064200 |
0.393 |
|
2001 |
Iida J, Pei D, Kang T, Simpson MA, Herlyn M, Furcht LT, McCarthy JB. Melanoma chondroitin sulfate proteoglycan regulates matrix metalloproteinase-dependent human melanoma invasion into type I collagen. The Journal of Biological Chemistry. 276: 18786-94. PMID 11278606 DOI: 10.1074/Jbc.M010053200 |
0.329 |
|
1999 |
Eisenmann KM, McCarthy JB, Simpson MA, Keely PJ, Guan JL, Tachibana K, Lim L, Manser E, Furcht LT, Iida J. Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas Nature Cell Biology. 1: 507-513. PMID 10587647 DOI: 10.1038/70302 |
0.372 |
|
1999 |
Simpson MA, LiCata VJ, Coe NR, Bernlohr DA. Biochemical and biophysical analysis of the intracellular lipid binding proteins of adipocytes Molecular and Cellular Biochemistry. 192: 33-40. PMID 10331656 DOI: 10.1023/A:1006819715146 |
0.539 |
|
1999 |
Coe NR, Simpson MA, Bernlohr DA. Targeted disruption of the adipocyte lipid-binding protein (aP2 protein) gene impairs fat cell lipolysis and increases cellular fatty acid levels Journal of Lipid Research. 40: 967-972. PMID 10224167 |
0.516 |
|
1998 |
Simpson MA, Bernlohr DA. Analysis of a series of phenylalanine 57 mutants of the adipocyte lipid- binding protein Biochemistry. 37: 10980-10986. PMID 9692991 DOI: 10.1021/Bi980507A |
0.54 |
|
1997 |
Bernlohr DA, Coe NR, Simpson MA, Hertzel AV. Regulation of gene expression in adipose cells by polyunsaturated fatty acids Advances in Experimental Medicine and Biology. 422: 145-156. PMID 9361822 DOI: 10.1007/978-1-4757-2670-1_12 |
0.56 |
|
1997 |
Bernlohr DA, Simpson MA, Hertzel AV, Banaszak LJ. Intracellular lipid-binding proteins and their genes. Annual Review of Nutrition. 17: 277-303. PMID 9240929 DOI: 10.1146/Annurev.Nutr.17.1.277 |
0.561 |
|
1997 |
Ory J, Kane CD, Simpson MA, Banaszak LJ, Bernlohr DA. Biochemical and crystallographic analyses of a portal mutant of the adipocyte lipid-binding protein. The Journal of Biological Chemistry. 272: 9793-801. PMID 9092513 DOI: 10.1074/Jbc.272.15.9793 |
0.547 |
|
1996 |
Bernlohr DA, Simpson MA. Chapter 10 Adipose tissue and lipid metabolism New Comprehensive Biochemistry. 31: 257-281. DOI: 10.1016/S0167-7306(08)60517-7 |
0.53 |
|
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