Amity L. Manning, Ph.D. - Publications

Affiliations: 
2008 Biochemistry Dartmouth College, Hanover, NH, United States 
Area:
Biochemistry, Cell Biology

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zamalloa LG, Pruitt MM, Hermance NM, Gali H, Flynn RL, Manning AL. RB loss sensitizes cells to replication-associated DNA damage after PARP inhibition by trapping. Life Science Alliance. 6. PMID 37704395 DOI: 10.26508/lsa.202302067  0.306
2023 Mercadante DL, Aaron WA, Olson SD, Manning AL. Cortical Dynein Drives Centrosome Clustering in Cells with Centrosome Amplification. Molecular Biology of the Cell. mbcE22070296. PMID 37017483 DOI: 10.1091/mbc.E22-07-0296  0.335
2022 Crowley EA, Hermance NM, Herlihy CP, Manning AL. Suppression of chromosome instability limits acquired drug resistance. Molecular Cancer Therapeutics. PMID 35905505 DOI: 10.1158/1535-7163.MCT-22-0263  0.308
2021 Herlihy CP, Hahn S, Hermance NM, Crowley EA, Manning AL. Suv420 enrichment at the centromere limits Aurora B localization and function. Journal of Cell Science. 134. PMID 34342353 DOI: 10.1242/jcs.249763  0.382
2021 Herlihy CP, Hahn S, Hermance NM, Crowley EA, Manning AL. Suv420 enrichment at the centromere limits Aurora B localization and function. Journal of Cell Science. PMID 34251439 DOI: 10.1242/jcs.249763  0.354
2021 Mercadante DL, Manning AL, Olson SD. Modeling reveals cortical dynein-dependent fluctuations in bipolar spindle length. Biophysical Journal. PMID 34197801 DOI: 10.1016/j.bpj.2021.05.030  0.347
2021 Quinton RJ, DiDomizio A, Vittoria MA, Kotýnková K, Ticas CJ, Patel S, Koga Y, Vakhshoorzadeh J, Hermance N, Kuroda TS, Parulekar N, Taylor AM, Manning AL, Campbell JD, Ganem NJ. Publisher Correction: Whole-genome doubling confers unique genetic vulnerabilities on tumour cells. Nature. PMID 33976417 DOI: 10.1038/s41586-021-03591-3  0.65
2021 Quinton RJ, DiDomizio A, Vittoria MA, Kotýnková K, Ticas CJ, Patel S, Koga Y, Vakhshoorzadeh J, Hermance N, Kuroda TS, Parulekar N, Taylor AM, Manning AL, Campbell JD, Ganem NJ. Whole-genome doubling confers unique genetic vulnerabilities on tumour cells. Nature. PMID 33505027 DOI: 10.1038/s41586-020-03133-3  0.716
2019 Mercadante DL, Crowley EA, Manning AL. Live Cell Imaging to Assess the Dynamics of Metaphase Timing and Cell Fate Following Mitotic Spindle Perturbations. Journal of Visualized Experiments : Jove. PMID 31589210 DOI: 10.3791/60255  0.345
2019 Lim S, Hermance N, Mudianto T, Mustaly HM, Mauricio IPM, Vittoria MA, Quinton RJ, Howell BW, Cornils H, Manning AL, Ganem NJ. Identification of the kinase STK25 as an upstream activator of LATS signaling. Nature Communications. 10: 1547. PMID 30948712 DOI: 10.1038/S41467-019-09597-W  0.635
2019 Navarro-Serer B, Childers EP, Hermance NM, Mercadante D, Manning AL. Aurora A inhibition limits centrosome clustering and promotes mitotic catastrophe in cells with supernumerary centrosomes. Oncotarget. 10: 1649-1659. PMID 30899434 DOI: 10.18632/oncotarget.26714  0.427
2016 Nicolay BN, Danielian PS, Kottakis F, Lapek JD, Sanidas I, Miles WO, Dehnad M, Tschöp K, Gierut JJ, Manning AL, Morris R, Haigis K, Bardeesy N, Lees JA, Haas W, et al. Abstract IA15: The consequences of pRb inactivation: insights from a proteomic analysis of Rb loss Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Cellcycle16-Ia15  0.385
2015 Nicolay BN, Danielian PS, Kottakis F, Lapek JD, Sanidas I, Miles WO, Dehnad M, Tschöp K, Gierut JJ, Manning AL, Morris R, Haigis K, Bardeesy N, Lees JA, Haas W, et al. Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation. Genes & Development. 29: 1875-89. PMID 26314710 DOI: 10.1101/Gad.264127.115  0.337
2014 Manning AL, Yazinski SA, Nicolay B, Bryll A, Zou L, Dyson NJ. Suppression of genome instability in pRB-deficient cells by enhancement of chromosome cohesion. Molecular Cell. 53: 993-1004. PMID 24613344 DOI: 10.1016/J.Molcel.2014.01.032  0.461
2014 Manning AL, Benes C, Dyson NJ. Whole chromosome instability resulting from the synergistic effects of pRB and p53 inactivation. Oncogene. 33: 2487-94. PMID 23792446 DOI: 10.1038/Onc.2013.201  0.491
2013 Evertts AG, Manning AL, Wang X, Dyson NJ, Garcia BA, Coller HA. H4K20 methylation regulates quiescence and chromatin compaction. Molecular Biology of the Cell. 24: 3025-37. PMID 23924899 DOI: 10.1091/Mbc.E12-07-0529  0.373
2013 Black JC, Manning AL, Van Rechem C, Kim J, Ladd B, Cho J, Pineda CM, Murphy N, Daniels DL, Montagna C, Lewis PW, Glass K, Allis CD, Dyson NJ, Getz G, et al. KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors. Cell. 154: 541-55. PMID 23871696 DOI: 10.1016/J.Cell.2013.06.051  0.416
2012 Manning AL, Dyson NJ. RB: mitotic implications of a tumour suppressor. Nature Reviews. Cancer. 12: 220-6. PMID 22318235 DOI: 10.1038/Nrc3216  0.518
2012 Zhang J, Benavente CA, McEvoy J, Flores-Otero J, Ding L, Chen X, Ulyanov A, Wu G, Wilson M, Wang J, Brennan R, Rusch M, Manning AL, Ma J, Easton J, et al. A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature. 481: 329-34. PMID 22237022 DOI: 10.1038/Nature10733  0.377
2011 Manning AL, Dyson NJ. pRB, a tumor suppressor with a stabilizing presence. Trends in Cell Biology. 21: 433-41. PMID 21664133 DOI: 10.1016/J.Tcb.2011.05.003  0.395
2010 Centore RC, Havens CG, Manning AL, Li JM, Flynn RL, Tse A, Jin J, Dyson NJ, Walter JC, Zou L. CRL4(Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase. Molecular Cell. 40: 22-33. PMID 20932472 DOI: 10.1016/J.Molcel.2010.09.015  0.331
2010 Manning AL, Bakhoum SF, Maffini S, Correia-Melo C, Maiato H, Compton DA. CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity. The Embo Journal. 29: 3531-43. PMID 20852589 DOI: 10.1038/Emboj.2010.230  0.728
2010 Manning AL, Longworth MS, Dyson NJ. Loss of pRB causes centromere dysfunction and chromosomal instability. Genes & Development. 24: 1364-76. PMID 20551165 DOI: 10.1101/Gad.1917310  0.542
2009 Maffini S, Maia AR, Manning AL, Maliga Z, Pereira AL, Junqueira M, Shevchenko A, Hyman A, Yates JR, Galjart N, Compton DA, Maiato H. Motor-independent targeting of CLASPs to kinetochores by CENP-E promotes microtubule turnover and poleward flux. Current Biology : Cb. 19: 1566-72. PMID 19733075 DOI: 10.1016/J.Cub.2009.07.059  0.701
2009 Bakhoum SF, Thompson SL, Manning AL, Compton DA. Genome stability is ensured by temporal control of kinetochore-microtubule dynamics. Nature Cell Biology. 11: 27-35. PMID 19060894 DOI: 10.1038/Ncb1809  0.732
2008 Manning AL, Compton DA. SnapShot: Nonmotor proteins in spindle assembly. Cell. 134: 694. PMID 18724941 DOI: 10.1016/J.Cell.2008.08.001  0.72
2008 Manning AL, Compton DA. Structural and regulatory roles of nonmotor spindle proteins. Current Opinion in Cell Biology. 20: 101-6. PMID 18178073 DOI: 10.1016/J.Ceb.2007.11.004  0.718
2007 Manning AL, Ganem NJ, Bakhoum SF, Wagenbach M, Wordeman L, Compton DA. The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells. Molecular Biology of the Cell. 18: 2970-9. PMID 17538014 DOI: 10.1091/Mbc.E07-02-0110  0.707
2007 Manning AL, Compton DA. Mechanisms of spindle-pole organization are influenced by kinetochore activity in mammalian cells. Current Biology : Cb. 17: 260-5. PMID 17276919 DOI: 10.1016/J.Cub.2006.11.071  0.68
2004 Moseley JB, Sagot I, Manning AL, Xu Y, Eck MJ, Pellman D, Goode BL. A conserved mechanism for Bni1- and mDia1-induced actin assembly and dual regulation of Bni1 by Bud6 and profilin. Molecular Biology of the Cell. 15: 896-907. PMID 14657240 DOI: 10.1091/Mbc.E03-08-0621  0.413
2003 Rodal AA, Manning AL, Goode BL, Drubin DG. Negative regulation of yeast WASp by two SH3 domain-containing proteins. Current Biology : Cb. 13: 1000-8. PMID 12814545 DOI: 10.1016/S0960-9822(03)00383-X  0.385
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