| Year |
Citation |
Score |
| 2023 |
Zapata Bustos R, Coletta DK, Galons JP, Davidson LB, Langlais PR, Funk JL, Willis WT, Mandarino LJ. Nonequilibrium thermodynamics and mitochondrial protein content predict insulin sensitivity and fuel selection during exercise in human skeletal muscle. Frontiers in Physiology. 14: 1208186. PMID 37485059 DOI: 10.3389/fphys.2023.1208186 |
0.412 |
|
| 2023 |
Mandarino LJ, Willis WT. Can non-equilibrium thermodynamics explain skeletal muscle insulin resistance due to low mitochondrial content? The Lancet. Diabetes & Endocrinology. 11: 149-151. PMID 36822742 DOI: 10.1016/S2213-8587(23)00032-3 |
0.367 |
|
| 2022 |
Barakati N, Zapata Bustos R, Coletta DK, Langlais PR, Kohler LN, Luo M, Funk JL, Willis WT, Mandarino LJ. Fuel Selection in Skeletal Muscle Exercising at Low Intensity; Reliance on Carbohydrate in Very Sedentary Individuals. Metabolic Syndrome and Related Disorders. PMID 36318809 DOI: 10.1089/met.2022.0062 |
0.317 |
|
| 2020 |
Bustos RZ, Langlais PR, Coletta DK, Filippis EAD, Grandjean D, Mandarino L. 166-OR: Lower Response of Connective Tissue Growth Factor (CTGF) to Exercise Characterizes Insulin Resistant Muscle Diabetes. 69. DOI: 10.2337/Db20-166-Or |
0.456 |
|
| 2018 |
Tran L, Kras KA, Hoffman N, Ravichandran J, Dickinson JM, D'Lugos A, Carroll CC, Patel SH, Mandarino LJ, Roust L, Katsanos CS. Lower Fasted-State but Greater Increase in Muscle Protein Synthesis in Response to Elevated Plasma Amino Acids in Obesity. Obesity (Silver Spring, Md.). PMID 29896930 DOI: 10.1002/Oby.22213 |
0.676 |
|
| 2016 |
Tran L, Hanavan PD, Campbell LE, De Filippis E, Lake DF, Coletta DK, Roust LR, Mandarino LJ, Carroll CC, Katsanos CS. Prolonged Exposure of Primary Human Muscle Cells to Plasma Fatty Acids Associated with Obese Phenotype Induces Persistent Suppression of Muscle Mitochondrial ATP Synthase β Subunit. Plos One. 11: e0160057. PMID 27532680 DOI: 10.1371/Journal.Pone.0160057 |
0.671 |
|
| 2016 |
Xie X, Yi Z, Sinha S, Madan M, Bowen BP, Langlais P, Ma D, Mandarino L, Meyer C. Proteomics analyses of subcutaneous adipocytes reveal novel abnormalities in human insulin resistance. Obesity (Silver Spring, Md.). 24: 1506-14. PMID 27345962 DOI: 10.1002/Oby.21528 |
0.422 |
|
| 2015 |
McLean CS, Mielke C, Cordova JM, Langlais PR, Bowen B, Miranda D, Coletta DK, Mandarino LJ. Gene and MicroRNA Expression Responses to Exercise; Relationship with Insulin Sensitivity. Plos One. 10: e0127089. PMID 25984722 DOI: 10.1371/Journal.Pone.0127089 |
0.548 |
|
| 2015 |
Everman S, Mandarino LJ, Carroll CC, Katsanos CS. Effects of acute exposure to increased plasma branched-chain amino acid concentrations on insulin-mediated plasma glucose turnover in healthy young subjects. Plos One. 10: e0120049. PMID 25781654 DOI: 10.1371/Journal.Pone.0120049 |
0.754 |
|
| 2014 |
Mielke C, Lefort N, McLean CG, Cordova JM, Langlais PR, Bordner AJ, Te JA, Ozkan SB, Willis WT, Mandarino LJ. Adenine nucleotide translocase is acetylated in vivo in human muscle: Modeling predicts a decreased ADP affinity and altered control of oxidative phosphorylation. Biochemistry. 53: 3817-29. PMID 24884163 DOI: 10.1021/Bi401651E |
0.77 |
|
| 2014 |
Mielke CJ, Mandarino LJ, Dinu V. AMASS: a database for investigating protein structures. Bioinformatics (Oxford, England). 30: 1595-600. PMID 24497503 DOI: 10.1093/bioinformatics/btu073 |
0.472 |
|
| 2013 |
Chakkera HA, Mandarino LJ. Calcineurin inhibition and new-onset diabetes mellitus after transplantation. Transplantation. 95: 647-52. PMID 23076551 DOI: 10.1097/TP.0b013e31826e592e |
0.351 |
|
| 2013 |
Puga GM, Meyer C, Mandarino LJ, Katsanos CS. Increased plasma availability of L-arginine in the postprandial period decreases the postprandial lipemia in older adults. Nutrition (Burbank, Los Angeles County, Calif.). 29: 81-8. PMID 22959634 DOI: 10.1016/j.nut.2012.04.010 |
0.625 |
|
| 2012 |
Luo M, Mengos AE, Stubblefield TM, Mandarino LJ. High Fat Diet-Induced Changes in Hepatic Protein Abundance in Mice. Journal of Proteomics & Bioinformatics. 5: 60-66. PMID 33907358 DOI: 10.4172/jpb.1000214 |
0.307 |
|
| 2012 |
Langlais P, Dillon JL, Mengos A, Baluch DP, Ardebili R, Miranda DN, Xie X, Heckmann BL, Liu J, Mandarino LJ. Identification of a role for CLASP2 in insulin action Journal of Biological Chemistry. 287: 39245-39253. PMID 22992739 DOI: 10.1074/Jbc.M112.394148 |
0.353 |
|
| 2012 |
Puga GM, Meyer C, Mandarino LJ, Katsanos CS. Postprandial spillover of dietary lipid into plasma is increased with moderate amounts of ingested fat and is inversely related to adiposity in healthy older men. The Journal of Nutrition. 142: 1806-11. PMID 22955513 DOI: 10.3945/jn.112.162008 |
0.642 |
|
| 2012 |
Chao A, Zhang X, Ma D, Langlais P, Luo M, Mandarino LJ, Zingsheim M, Pham K, Dillon J, Yi Z. Site-specific phosphorylation of protein phosphatase 1 regulatory subunit 12A stimulated or suppressed by insulin. Journal of Proteomics. 75: 3342-50. PMID 22516431 DOI: 10.1016/j.jprot.2012.03.043 |
0.303 |
|
| 2012 |
Luo M, Mengos AE, Stubblefield TM, Mandarino LJ. High fat diet-induced changes in hepatic protein abundance in mice Journal of Proteomics and Bioinformatics. 5: 60-66. |
0.305 |
|
| 2011 |
Everman S, Yi Z, Langlais P, Mandarino LJ, Luo M, Roberts C, Katsanos CS. Reproducibility of an HPLC-ESI-MS/MS method for the measurement of stable-isotope enrichment of in vivo-labeled muscle ATP synthase beta subunit. Plos One. 6: e26171. PMID 22022551 DOI: 10.1371/Journal.Pone.0026171 |
0.718 |
|
| 2011 |
Coletta DK, Mandarino LJ. Mitochondrial dysfunction and insulin resistance from the outside in: extracellular matrix, the cytoskeleton, and mitochondria. American Journal of Physiology. Endocrinology and Metabolism. 301: E749-55. PMID 21862724 DOI: 10.1152/ajpendo.00363.2011 |
0.41 |
|
| 2011 |
Langlais P, Yi Z, Finlayson J, Luo M, Mapes R, De Filippis E, Meyer C, Plummer E, Tongchinsub P, Mattern M, Mandarino LJ. Global IRS-1 phosphorylation analysis in insulin resistance Diabetologia. 54: 2878-2889. PMID 21850561 DOI: 10.1007/s00125-011-2271-9 |
0.32 |
|
| 2011 |
Ghosh S, Lertwattanarak R, Lefort N, Molina-Carrion M, Joya-Galeana J, Bowen BP, Garduno-Garcia Jde J, Abdul-Ghani M, Richardson A, DeFronzo RA, Mandarino L, Van Remmen H, Musi N. Reduction in reactive oxygen species production by mitochondria from elderly subjects with normal and impaired glucose tolerance. Diabetes. 60: 2051-60. PMID 21677280 DOI: 10.2337/Db11-0121 |
0.698 |
|
| 2011 |
Puga GM, Meyer C, Everman S, Mandarino LJ, Katsanos CS. Postprandial lipemia in the elderly involves increased incorporation of ingested fat in plasma free fatty acids and small (Sf 20-400) triglyceride-rich lipoproteins. American Journal of Physiology. Endocrinology and Metabolism. 301: E356-61. PMID 21558545 DOI: 10.1152/Ajpendo.00670.2010 |
0.723 |
|
| 2011 |
Geetha T, Langlais P, Luo M, Mapes R, Lefort N, Chen SC, Mandarino LJ, Yi Z. Label-free proteomic identification of endogenous, insulin-stimulated interaction partners of insulin receptor substrate-1. Journal of the American Society For Mass Spectrometry. 22: 457-66. PMID 21472564 DOI: 10.1007/S13361-010-0051-2 |
0.712 |
|
| 2011 |
Katsanos CS, Mandarino LJ. Protein metabolism in human obesity: a shift in focus from whole-body to skeletal muscle. Obesity (Silver Spring, Md.). 19: 469-75. PMID 21164506 DOI: 10.1038/oby.2010.290 |
0.66 |
|
| 2010 |
Kashyap SR, Roman LJ, Mandarino L, DeFronzo R, Bajaj M. Hypoadiponectinemia is closely associated with impaired nitric oxide synthase activity in skeletal muscle of type 2 diabetic subjects. Metabolic Syndrome and Related Disorders. 8: 459-63. PMID 20854065 DOI: 10.1089/Met.2010.0018 |
0.336 |
|
| 2010 |
Lefort N, Glancy B, Bowen B, Willis WT, Bailowitz Z, De Filippis EA, Brophy C, Meyer C, Højlund K, Yi Z, Mandarino LJ. Increased reactive oxygen species production and lower abundance of complex I subunits and carnitine palmitoyltransferase 1B protein despite normal mitochondrial respiration in insulin-resistant human skeletal muscle. Diabetes. 59: 2444-52. PMID 20682693 DOI: 10.2337/Db10-0174 |
0.742 |
|
| 2010 |
Civitarese AE, MacLean PS, Carling S, Kerr-Bayles L, McMillan RP, Pierce A, Becker TC, Moro C, Finlayson J, Lefort N, Newgard CB, Mandarino L, Cefalu W, Walder K, Collier GR, et al. Regulation of skeletal muscle oxidative capacity and insulin signaling by the mitochondrial rhomboid protease PARL. Cell Metabolism. 11: 412-26. PMID 20444421 DOI: 10.1016/J.Cmet.2010.04.004 |
0.747 |
|
| 2010 |
Højlund K, Yi Z, Lefort N, Langlais P, Bowen B, Levin K, Beck-Nielsen H, Mandarino LJ. Human ATP synthase beta is phosphorylated at multiple sites and shows abnormal phosphorylation at specific sites in insulin-resistant muscle. Diabetologia. 53: 541-51. PMID 20012595 DOI: 10.1007/S00125-009-1624-0 |
0.72 |
|
| 2010 |
Hwang H, Bowen BP, Lefort N, Flynn CR, De Filippis EA, Roberts C, Smoke CC, Meyer C, Højlund K, Yi Z, Mandarino LJ. Proteomics analysis of human skeletal muscle reveals novel abnormalities in obesity and type 2 diabetes. Diabetes. 59: 33-42. PMID 19833877 DOI: 10.2337/Db09-0214 |
0.732 |
|
| 2009 |
Højlund K, Bowen BP, Hwang H, Flynn CR, Madireddy L, Geetha T, Langlais P, Meyer C, Mandarino LJ, Yi Z. In vivo phosphoproteome of human skeletal muscle revealed by phosphopeptide enrichment and HPLC-ESI-MS/MS. Journal of Proteome Research. 8: 4954-65. PMID 19764811 DOI: 10.1021/Pr9007267 |
0.312 |
|
| 2009 |
Lefort N, Yi Z, Bowen B, Glancy B, De Filippis EA, Mapes R, Hwang H, Flynn CR, Willis WT, Civitarese A, Højlund K, Mandarino LJ. Proteome profile of functional mitochondria from human skeletal muscle using one-dimensional gel electrophoresis and HPLC-ESI-MS/MS. Journal of Proteomics. 72: 1046-60. PMID 19567276 DOI: 10.1016/J.Jprot.2009.06.011 |
0.701 |
|
| 2008 |
Yi Z, Bowen BP, Hwang H, Jenkinson CP, Coletta DK, Lefort N, Bajaj M, Kashyap S, Berria R, De Filippis EA, Mandarino LJ. Global relationship between the proteome and transcriptome of human skeletal muscle. Journal of Proteome Research. 7: 3230-41. PMID 18613714 DOI: 10.1021/Pr800064S |
0.715 |
|
| 2008 |
Coletta DK, Balas B, Chavez AO, Baig M, Abdul-Ghani M, Kashyap SR, Folli F, Tripathy D, Mandarino LJ, Cornell JE, Defronzo RA, Jenkinson CP. Effect of acute physiological hyperinsulinemia on gene expression in human skeletal muscle in vivo. American Journal of Physiology. Endocrinology and Metabolism. 294: E910-7. PMID 18334611 DOI: 10.1152/ajpendo.00607.2007 |
0.326 |
|
| 2008 |
De Filippis E, Alvarez G, Berria R, Cusi K, Everman S, Meyer C, Mandarino LJ. Insulin-resistant muscle is exercise resistant: evidence for reduced response of nuclear-encoded mitochondrial genes to exercise. American Journal of Physiology. Endocrinology and Metabolism. 294: E607-14. PMID 18182465 DOI: 10.1152/Ajpendo.00729.2007 |
0.778 |
|
| 2008 |
Højlund K, Yi Z, Hwang H, Bowen B, Lefort N, Flynn CR, Langlais P, Weintraub ST, Mandarino LJ. Characterization of the human skeletal muscle proteome by one-dimensional gel electrophoresis and HPLC-ESI-MS/MS. Molecular & Cellular Proteomics : McP. 7: 257-67. PMID 17911086 DOI: 10.1074/Mcp.M700304-Mcp200 |
0.72 |
|
| 2007 |
Luo M, Langlais P, Yi Z, Lefort N, De Filippis EA, Hwang H, Christ-Roberts CY, Mandarino LJ. Phosphorylation of human insulin receptor substrate-1 at Serine 629 plays a positive role in insulin signaling. Endocrinology. 148: 4895-905. PMID 17640984 DOI: 10.1210/En.2007-0049 |
0.684 |
|
| 2007 |
Yi Z, Langlais P, De Filippis EA, Luo M, Flynn CR, Schroeder S, Weintraub ST, Mapes R, Mandarino LJ. Global assessment of regulation of phosphorylation of insulin receptor substrate-1 by insulin in vivo in human muscle. Diabetes. 56: 1508-16. PMID 17360977 DOI: 10.2337/Db06-1355 |
0.323 |
|
| 2007 |
Bajaj M, Medina-Navarro R, Suraamornkul S, Meyer C, DeFronzo RA, Mandarino LJ. Paradoxical changes in muscle gene expression in insulin-resistant subjects after sustained reduction in plasma free fatty acid concentration. Diabetes. 56: 743-52. PMID 17327445 DOI: 10.2337/db06-0840 |
0.386 |
|
| 2007 |
Pendergrass M, Bertoldo A, Bonadonna R, Nucci G, Mandarino L, Cobelli C, Defronzo RA. Muscle glucose transport and phosphorylation in type 2 diabetic, obese nondiabetic, and genetically predisposed individuals. American Journal of Physiology. Endocrinology and Metabolism. 292: E92-100. PMID 16896161 DOI: 10.1152/Ajpendo.00617.2005 |
0.434 |
|
| 2006 |
Civitarese AE, Ukropcova B, Carling S, Hulver M, DeFronzo RA, Mandarino L, Ravussin E, Smith SR. Role of adiponectin in human skeletal muscle bioenergetics. Cell Metabolism. 4: 75-87. PMID 16814734 DOI: 10.1016/J.Cmet.2006.05.002 |
0.454 |
|
| 2006 |
Maddux BA, Chan A, De Filippis EA, Mandarino LJ, Goldfine ID. IGF-binding protein-1 levels are related to insulin-mediated glucose disposal and are a potential serum marker of insulin resistance. Diabetes Care. 29: 1535-7. PMID 16801575 DOI: 10.2337/dc05-1367 |
0.322 |
|
| 2006 |
Sriwijitkamol A, Christ-Roberts C, Berria R, Eagan P, Pratipanawatr T, DeFronzo RA, Mandarino LJ, Musi N. Reduced skeletal muscle inhibitor of kappaB beta content is associated with insulin resistance in subjects with type 2 diabetes: reversal by exercise training. Diabetes. 55: 760-7. PMID 16505240 |
0.353 |
|
| 2006 |
Berria R, Wang L, Richardson DK, Finlayson J, Belfort R, Pratipanawatr T, De Filippis EA, Kashyap S, Mandarino LJ. Increased collagen content in insulin-resistant skeletal muscle. American Journal of Physiology. Endocrinology and Metabolism. 290: E560-5. PMID 16249255 DOI: 10.1152/ajpendo.00202.2005 |
0.383 |
|
| 2006 |
Civitarese A, Nawrocki A, Ukropcova B, Carling S, Hulver M, DeFronzo R, Mandarino L, Scherer P, Smith S, Ravussin E. NIA0002 Novel role for adiponectin pathway in human skeletal muscle bioenergetics Obesity Reviews. 7: 37-37. DOI: 10.1111/J.1467-7881.2006.00280_8.X |
0.313 |
|
| 2005 |
Bajaj M, Suraamornkul S, Romanelli A, Cline GW, Mandarino LJ, Shulman GI, DeFronzo RA. Effect of a sustained reduction in plasma free fatty acid concentration on intramuscular long-chain fatty acyl-CoAs and insulin action in type 2 diabetic patients Diabetes. 54: 3148-3153. PMID 16249438 DOI: 10.2337/Diabetes.54.11.3148 |
0.356 |
|
| 2005 |
Belfort R, Mandarino L, Kashyap S, Wirfel K, Pratipanawatr T, Berria R, Defronzo RA, Cusi K. Dose-response effect of elevated plasma free fatty acid on insulin signaling. Diabetes. 54: 1640-8. PMID 15919784 DOI: 10.2337/Diabetes.54.6.1640 |
0.46 |
|
| 2005 |
Walder K, Kerr-Bayles L, Civitarese A, Jowett J, Curran J, Elliott K, Trevaskis J, Bishara N, Zimmet P, Mandarino L, Ravussin E, Blangero J, Kissebah A, Collier GR. The mitochondrial rhomboid protease PSARL is a new candidate gene for type 2 diabetes. Diabetologia. 48: 459-68. PMID 15729572 DOI: 10.1007/S00125-005-1675-9 |
0.344 |
|
| 2005 |
Richardson DK, Kashyap S, Bajaj M, Cusi K, Mandarino SJ, Finlayson J, DeFronzo RA, Jenkinson CP, Mandarino LJ. Lipid infusion decreases the expression of nuclear encoded mitochondrial genes and increases the expression of extracellular matrix genes in human skeletal muscle. The Journal of Biological Chemistry. 280: 10290-7. PMID 15598661 DOI: 10.1074/jbc.M408985200 |
0.332 |
|
| 2004 |
Bajaj M, Suraamornkul S, Kashyap S, Cusi K, Mandarino L, DeFronzo RA. Sustained reduction in plasma free fatty acid concentration improves insulin action without altering plasma adipocytokine levels in subjects with strong family history of type 2 diabetes. The Journal of Clinical Endocrinology and Metabolism. 89: 4649-55. PMID 15356076 DOI: 10.1210/Jc.2004-0224 |
0.455 |
|
| 2004 |
Miyazaki Y, Mahankali A, Wajcberg E, Bajaj M, Mandarino LJ, DeFronzo RA. Effect of pioglitazone on circulating adipocytokine levels and insulin sensitivity in type 2 diabetic patients. The Journal of Clinical Endocrinology and Metabolism. 89: 4312-9. PMID 15356026 DOI: 10.1210/jc.2004-0190 |
0.34 |
|
| 2004 |
Christ-Roberts CY, Pratipanawatr T, Pratipanawatr W, Berria R, Belfort R, Kashyap S, Mandarino LJ. Exercise training increases glycogen synthase activity and GLUT4 expression but not insulin signaling in overweight nondiabetic and type 2 diabetic subjects. Metabolism: Clinical and Experimental. 53: 1233-42. PMID 15334390 DOI: 10.1016/j.metabol.2004.03.022 |
0.307 |
|
| 2004 |
Christ-Roberts CY, Mandarino LJ. Glycogen synthase: key effect of exercise on insulin action. Exercise and Sport Sciences Reviews. 32: 90-4. PMID 15243203 DOI: 10.1097/00003677-200407000-00003 |
0.335 |
|
| 2004 |
Kashyap SR, Belfort R, Berria R, Suraamornkul S, Pratipranawatr T, Finlayson J, Barrentine A, Bajaj M, Mandarino L, DeFronzo R, Cusi K. Discordant effects of a chronic physiological increase in plasma FFA on insulin signaling in healthy subjects with or without a family history of type 2 diabetes. American Journal of Physiology. Endocrinology and Metabolism. 287: E537-46. PMID 15126243 DOI: 10.1152/Ajpendo.00541.2003 |
0.482 |
|
| 2004 |
Civitarese AE, Jenkinson CP, Richardson D, Bajaj M, Cusi K, Kashyap S, Berria R, Belfort R, DeFronzo RA, Mandarino LJ, Ravussin E. Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes Diabetologia. 47: 816-820. PMID 15105989 DOI: 10.1007/S00125-004-1359-X |
0.317 |
|
| 2004 |
Bays H, Mandarino L, DeFronzo RA. Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach. The Journal of Clinical Endocrinology and Metabolism. 89: 463-78. PMID 14764748 DOI: 10.1210/Jc.2003-030723 |
0.488 |
|
| 2004 |
Adams JM, Pratipanawatr T, Berria R, Wang E, DeFronzo RA, Sullards MC, Mandarino LJ. Ceramide content is increased in skeletal muscle from obese insulin-resistant humans. Diabetes. 53: 25-31. PMID 14693694 DOI: 10.2337/diabetes.53.1.25 |
0.405 |
|
| 2003 |
Kashyap S, Belfort R, Gastaldelli A, Pratipanawatr T, Berria R, Pratipanawatr W, Bajaj M, Mandarino L, DeFronzo R, Cusi K. A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes. Diabetes. 52: 2461-74. PMID 14514628 DOI: 10.2337/Diabetes.52.10.2461 |
0.449 |
|
| 2003 |
Christ-Roberts CY, Pratipanawatr T, Pratipanawatr W, Berria R, Belfort R, Mandarino LJ. Increased insulin receptor signaling and glycogen synthase activity contribute to the synergistic effect of exercise on insulin action. Journal of Applied Physiology (Bethesda, Md. : 1985). 95: 2519-29. PMID 12909611 DOI: 10.1152/japplphysiol.00605.2003 |
0.316 |
|
| 2003 |
Miyazaki Y, He H, Mandarino LJ, DeFronzo RA. Rosiglitazone improves downstream insulin receptor signaling in type 2 diabetic patients. Diabetes. 52: 1943-50. PMID 12882909 DOI: 10.2337/diabetes.52.8.1943 |
0.368 |
|
| 2003 |
Patti ME, Butte AJ, Crunkhorn S, Cusi K, Berria R, Kashyap S, Miyazaki Y, Kohane I, Costello M, Saccone R, Landaker EJ, Goldfine AB, Mun E, DeFronzo R, Finlayson J, ... ... Mandarino LJ, et al. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1. Proceedings of the National Academy of Sciences of the United States of America. 100: 8466-71. PMID 12832613 DOI: 10.1073/Pnas.1032913100 |
0.346 |
|
| 2002 |
Bajaj M, Pratipanawatr T, Berria R, Pratipanawatr W, Kashyap S, Cusi K, Mandarino L, DeFronzo RA. Free fatty acids reduce splanchnic and peripheral glucose uptake in patients with type 2 diabetes. Diabetes. 51: 3043-8. PMID 12351445 DOI: 10.2337/Diabetes.51.10.3043 |
0.41 |
|
| 2002 |
Bajaj M, Berria R, Pratipanawatr T, Kashyap S, Pratipanawatr W, Belfort R, Cusi K, Mandarino L, DeFronzo RA. Free fatty acid-induced peripheral insulin resistance augments splanchnic glucose uptake in healthy humans. American Journal of Physiology. Endocrinology and Metabolism. 283: E346-52. PMID 12110541 DOI: 10.1152/Ajpendo.00329.2001 |
0.42 |
|
| 2002 |
Miyazaki Y, Mahankali A, Matsuda M, Mahankali S, Hardies J, Cusi K, Mandarino LJ, DeFronzo RA. Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients. The Journal of Clinical Endocrinology and Metabolism. 87: 2784-91. PMID 12050251 DOI: 10.1210/jcem.87.6.8567 |
0.332 |
|
| 2002 |
Lee NA, Matsuda M, Bressler P, Pratipanawatr T, Glass L, Mandarino LJ, DeFronzo RA. Effect of misoprostol (PGE1) on glucose metabolism in type-2-diabetic and control subjects Diabetes, Obesity and Metabolism. 4: 195-200. PMID 12047398 DOI: 10.1046/j.1463-1326.2002.00203.x |
0.31 |
|
| 2002 |
Pratipanawatr T, Pratipanawatr W, Rosen C, Berria R, Bajaj M, Cusi K, Mandarino L, Kashyap S, Belfort R, DeFronzo RA. Effect of IGF-I on FFA and glucose metabolism in control and type 2 diabetic subjects. American Journal of Physiology. Endocrinology and Metabolism. 282: E1360-8. PMID 12006367 DOI: 10.1152/Ajpendo.00335.2001 |
0.43 |
|
| 2002 |
Pratipanawatr T, Cusi K, Ngo P, Pratipanawatr W, Mandarino LJ, DeFronzo RA. Normalization of plasma glucose concentration by insulin therapy improves insulin-stimulated glycogen synthesis in type 2 diabetes. Diabetes. 51: 462-8. PMID 11812756 |
0.357 |
|
| 2002 |
Christ CY, Hunt D, Hancock J, Garcia-Macedo R, Mandarino LJ, Ivy JL. Exercise training improves muscle insulin resistance but not insulin receptor signaling in obese Zucker rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 92: 736-44. PMID 11796688 DOI: 10.1152/japplphysiol.00784.2001 |
0.312 |
|
| 2001 |
Pratipanawatr W, Pratipanawatr T, Cusi K, Berria R, Adams JM, Jenkinson CP, Maezono K, DeFronzo RA, Mandarino LJ. Skeletal muscle insulin resistance in normoglycemic subjects with a strong family history of type 2 diabetes is associated with decreased insulin-stimulated insulin receptor substrate-1 tyrosine phosphorylation. Diabetes. 50: 2572-8. PMID 11679436 |
0.366 |
|
| 2001 |
Miyazaki Y, Mahankali A, Matsuda M, Glass L, Mahankali S, Ferrannini E, Cusi K, Mandarino LJ, DeFronzo RA. Improved glycemic control and enhanced insulin sensitivity in type 2 diabetic subjects treated with pioglitazone Diabetes Care. 24: 710-719. PMID 11315836 |
0.345 |
|
| 2001 |
Iozzo P, Pratipanawatr T, Pijl H, Vogt C, Kumar V, Pipek R, Matsuda M, Mandarino LJ, Cusi KJ, DeFronzo RA. Physiological hyperinsulinemia impairs insulin-stimulated glycogen synthase activity and glycogen synthesis American Journal of Physiology - Endocrinology and Metabolism. 280. PMID 11287353 |
0.392 |
|
| 2000 |
Kelley DE, Mandarino LJ. Fuel selection in human skeletal muscle in insulin resistance: A reexamination Diabetes. 49: 677-683. PMID 10905472 |
0.399 |
|
| 2000 |
Vogt C, Ardehali H, Iozzo P, Yki-Jarvinen H, Koval J, Maezono K, Pendergrass M, Printz R, Granner D, DeFronzo R, Mandarino L. Regulation of hexokinase II expression in human skeletal muscle in vivo Metabolism: Clinical and Experimental. 49: 814-818. PMID 10877213 DOI: 10.1053/Meta.2000.6245 |
0.376 |
|
| 2000 |
Cusi K, Maezono K, Osman A, Pendergrass M, Patti ME, Pratipanawatr T, DeFronzo RA, Kahn CR, Mandarino LJ. Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle Journal of Clinical Investigation. 105: 311-320. PMID 10675357 DOI: 10.1172/Jci7535 |
0.356 |
|
| 2000 |
Miyazaki Y, Mahankali A, Matsuda M, Cusi K, Mandarino L, Defronzo R. Effect of pioglitazone on glucose metabolism in sulfonylurea-treated patients with type 2 diabetes Diabetes Research and Clinical Practice. 50: 62. DOI: 10.1016/S0168-8227(00)81668-X |
0.307 |
|
| 2000 |
Mahankali A, Miyazaki Y, Matsuda M, Cusi K, Mandarino L, Defronzo R. Effect of pioglitazone on glucose tolerance and insulin sensitivity in diet-controlled type 2 diabetic subjects Diabetes Research and Clinical Practice. 50: 61-62. DOI: 10.1016/S0168-8227(00)81667-8 |
0.397 |
|
| 2000 |
Miyazaki Y, Mahankali A, Matsuda M, Mahankali S, Cusi K, Mandarino L, Defronzo R. Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in patients with type 2 diabetes Diabetes Research and Clinical Practice. 50: 61. DOI: 10.1016/S0168-8227(00)81666-6 |
0.363 |
|
| 1999 |
Koval JA, Maezono K, Patti ME, Pendergrass M, DeFronzo RA, Mandarino LJ. Effects of exercise and insulin on insulin signaling proteins in human skeletal muscle Medicine and Science in Sports and Exercise. 31: 998-1004. PMID 10416561 DOI: 10.1097/00005768-199907000-00012 |
0.353 |
|
| 1999 |
Matsuda M, Mandarino L, DeFronzo RA. Synergistic interaction of magnesium and vanadate on glucose metabolism in diabetic rats Metabolism: Clinical and Experimental. 48: 725-731. PMID 10381146 DOI: 10.1016/S0026-0495(99)90171-3 |
0.372 |
|
| 1998 |
Koopmans SJ, Mandarino L, DeFronzo RA. Time course of insulin action on tissue-specific intracellular glucose metabolism in normal rats American Journal of Physiology - Endocrinology and Metabolism. 274. PMID 9575825 DOI: 10.1152/Ajpendo.1998.274.4.E642 |
0.364 |
|
| 1998 |
Pendergrass M, Koval J, Vogt C, Yki-Jarvinen H, Iozzo P, Pipek R, Ardehali H, Printz R, Granner D, DeFronzo RA, Mandarino LJ. Insulin-induced hexokinase II expression is reduced in obesity and NIDDM Diabetes. 47: 387-394. PMID 9519744 DOI: 10.2337/Diabetes.47.3.387 |
0.355 |
|
| 1998 |
Vogt C, Yki-jarvinen H, Iozzo P, Pipek R, Pendergrass M, Koval J, Ardehali H, Printz R, Granner D, Defronzo R, Mandarino L. Effects of insulin on subcellular localization of hexokinase II in human skeletal muscle in vivo Journal of Clinical Endocrinology and Metabolism. 83: 230-234. PMID 9435447 DOI: 10.1210/Jc.83.1.230 |
0.496 |
|
| 1997 |
Koopmans SJ, Ohman L, Haywood JR, Mandarino LJ, DeFronzo RA. Seven days of euglycemic hyperinsulinemia induces insulin resistance for glucose metabolism but not hypertension, elevated catecholamine levels, or increased sodium retention in conscious normal rats. Diabetes. 46: 1572-8. PMID 9313752 |
0.3 |
|
| 1997 |
Yki-Järvinen H, Vogt C, Iozzo P, Pipek R, Daniels MC, Virkamäki A, Mäkimattila S, Mandarino L, DeFronzo RA, McClain D, Gottschalk WK. UDP-N-acetylglucosamine transferase and glutamine: Fructose 6-phosphate amidotransferase activities in insulin-sensitive tissues Diabetologia. 40: 76-81. PMID 9028721 DOI: 10.1007/S001250050645 |
0.416 |
|
| 1996 |
Mandarino LJ, Consoli A, Jain A, Kelley DE. Interaction of carbohydrate and fat fuels in human skeletal muscle: Impact of obesity and NIDDM American Journal of Physiology - Endocrinology and Metabolism. 270. PMID 8638694 |
0.38 |
|
| 1995 |
Mandarino LJ, Printz RL, Cusi KA, Kinchington P, O'Doherty RM, Osawa H, Sewell C, Consoli A, Granner DK, DeFronzo RA. Regulation of hexokinase II and glycogen synthase mRNA, protein, and activity in human muscle. The American Journal of Physiology. 269: E701-8. PMID 7485484 DOI: 10.1152/ajpendo.1995.269.4.E701 |
0.364 |
|
| 1993 |
Kelley DE, Mokan M, Mandarino LJ. Metabolic pathways of glucose in skeletal muscle of lean NIDDM patients Diabetes Care. 16: 1158-1166. PMID 8375246 |
0.336 |
|
| 1993 |
Kelley DE, Mokan M, Simoneau JA, Mandarino LJ. Interaction between glucose and free fatty acid metabolism in human skeletal muscle Journal of Clinical Investigation. 92: 91-98. PMID 8326021 |
0.309 |
|
| 1993 |
Mandarino LJ, Consoli A, Jain A, Kelley DE. Differential regulation of intracellular glucose metabolism by glucose and insulin in human muscle Am.J.Physiol.. 265. |
0.326 |
|
| 1992 |
Kelley DE, Mokan M, Mandarino LJ. Intracellular defects in glucose metabolism in obese patients with NIDDM Diabetes. 41: 698-706. PMID 1587397 |
0.362 |
|
| 1991 |
Kelley DE, Mandarino LJ. Hyperglycemia normalizes insulin-stimulated skeletal muscle glucose oxidation and storage in noninsulin-dependent diabetes mellitus. The Journal of Clinical Investigation. 86: 1999-2007. PMID 2123890 DOI: 10.1172/JCI114935 |
0.339 |
|
| 1990 |
Gerich JE, Mitrakou A, Kelley D, Mandarino L, Nurjhan N, Reilly J, Jenssen T, Veneman T, Consoli A. Contribution of impaired muscle glucose clearance to reduced postabsorptive systemic glucose clearance in NIDDM Diabetes. 39: 211-216. PMID 2227129 DOI: 10.2337/Diab.39.2.211 |
0.424 |
|
| 1990 |
Mandarino LJ, Consoli A, Kelley DE, Reilly JJ, Nurjhan N. Fasting hyperglycemia normalizes oxidative and nonoxidative pathways of insulin-stimulated glucose metabolism in noninsulin-dependent diabetes mellitus Journal of Clinical Endocrinology and Metabolism. 71: 1544-1551. PMID 2121778 |
0.36 |
|
| 1990 |
Kelley DE, Reilly JP, Veneman T, Mandarino LJ. Effects of insulin on skeletal muscle glucose storage, oxidation, and glycolysis in humans American Journal of Physiology - Endocrinology and Metabolism. 258. PMID 2113769 |
0.341 |
|
| 1988 |
Campbell PJ, Mandarino LJ, Gerich JE. Quantification of the relative impairment in actions of insulin on hepatic glucose production and peripheral glucose uptake in non-insulin-dependent diabetes mellitus Metabolism. 37: 15-21. PMID 3275857 DOI: 10.1016/0026-0495(88)90023-6 |
0.341 |
|
| 1988 |
Wright KS, Beck-Nielsen H, Kolterman OG, Mandarino LJ. Decreased activation of skeletal muscle glycogen synthase by mixed-meal ingestion in NIDDM Diabetes. 37: 436-440. PMID 2837418 |
0.361 |
|
| 1987 |
Madar Z, Bell JM, Mandarino LJ. Glycogen synthase kinetics in isolated human adipocytes: An in vitro model for the effects of insulin on glycogen synthase Biochemical Medicine and Metabolic Biology. 38: 265-271. PMID 3124871 DOI: 10.1016/0885-4505(87)90090-9 |
0.347 |
|
| 1987 |
Mandarino LJ, Wright KS, Verity LS, Nichols J, Bell JM, Kolterman OG, Beck-Nielsen H. Effects of insulin infusion on human skeletal muscle pyruvate dehydrogenase, phosphofructokinase, and glycogen synthase: Evidence for their role in oxidative and nonoxidative glucose metabolism Journal of Clinical Investigation. 80: 655-663. PMID 2957389 |
0.304 |
|
| 1986 |
Schwenk WF, Rizza RA, Mandarino LJ, Gerich JE, Hayles AB, Haymond MW. Familial insulin resistance and acanthosis nigricans: Presence of a postbinding defect Diabetes. 35: 33-37. PMID 3510137 |
0.313 |
|
| 1985 |
Dimitriadis G, Baker B, Marsh H, Mandarino L, Rizza R, Bergman R, Haymond M, Gerich J. Effect of thyroid hormone excess on action, secretion, and metabolism of insulin in humans The American Journal of Physiology. 248. PMID 3887944 DOI: 10.1152/Ajpendo.1985.248.5.E593 |
0.43 |
|
| 1985 |
Rizza RA, Mandarino LJ, Genest J, Baker BA, Gerich JE. Production of insulin resistance by hyperinsulinaemia in man Diabetologia. 28: 70-75. PMID 3884419 DOI: 10.1007/BF00279918 |
0.348 |
|
| 1984 |
Mandarino L, Tsalikian E, Bartold S, Marsh H, Carney A, Buerklin E, Tutwiler G, Haymond M, Handwerger B, Rizza R. Mechanism of hyperglycemia and response to treatment with an inhibitor of fatty acid oxidation in a patient with insulin resistance due to antiinsulin receptor antibodies Journal of Clinical Endocrinology and Metabolism. 59: 658-664. PMID 6480801 DOI: 10.1210/Jcem-59-4-658 |
0.428 |
|
| 1984 |
Mandarino L, Baker B, Rizza R, Genest J, Gerich J. Infusion of insulin impairs human adipocyte glucose metabolism in vitro without decreasing adipocyte insulin receptor binding Diabetologia. 27: 358-363. PMID 6389241 DOI: 10.1007/Bf00304850 |
0.448 |
|
| 1984 |
Mandarino LJ, Campbell PJ, Gottesman IS, Gerich JE. Abnormal coupling of insulin receptor binding in noninsulin-dependent diabetes The American Journal of Physiology. 247. PMID 6388357 |
0.323 |
|
| 1984 |
Baker B, Mandarino L, Brick B, Rizza R, Gerich J. Influence of changes in insulin receptor binding during insulin infusions on the shape of the insulin dose response curve for glucose disposal in man Journal of Clinical Endocrinology and Metabolism. 58: 392-396. PMID 6363438 DOI: 10.1210/Jcem-58-2-392 |
0.414 |
|
| 1984 |
Gottesman I, Mandarino L, Gerich J. Use of glucose uptake and glucose clearance for the evaluation of insulin action in vivo Diabetes. 33: 184-191. PMID 6363173 DOI: 10.2337/Diab.33.2.184 |
0.373 |
|
| 1984 |
Mandarino L. Insulin and glucagon binding to isolated hepatocytes of egyptian sand rats (Psammomys obesus): Evidence for an insulin receptor defect Comparative Biochemistry and Physiology -- Part a: Physiology. 78: 519-523. PMID 6147232 DOI: 10.1016/0300-9629(84)90589-9 |
0.384 |
|
| 1984 |
Veber DF, Saperstein R, Nutt RF, Freidinger RM, Brady SF, Curley P, Perlow DS, Paleveda WJ, Colton CD, Zacchei AG, Tocco DJ, Hoff DR, Vandlen RL, Gerich JE, Hall L, ... Mandarino L, et al. A super active cyclic hexapeptide analog of somatostatin Life Sciences. 34: 1371-1378. PMID 6143233 DOI: 10.1016/0024-3205(84)90009-2 |
0.348 |
|
| 1983 |
Gottesman I, Mandarino L, Gerich J. Estimation and kinetic analysis of insulin-independent glucose uptake in human subjects The American Journal of Physiology. 244. PMID 6344653 DOI: 10.1152/Ajpendo.1983.244.6.E632 |
0.429 |
|
| 1982 |
Rizza RA, Mandarino LJ, Gerich JE. Cortisol-induced insulin resistance in man: Impaired suppression of glucose production and stimulation of glucose utilization due to a postreceptor defect of insulin action Journal of Clinical Endocrinology and Metabolism. 54: 131-138. PMID 7033265 |
0.33 |
|
| 1982 |
Rizza RA, Mandarino LJ, Gerich JE. Effects of growth hormone on insulin action in man. Mechanisms of insulin resistance, impaired suppression of glucose production, and impaired stimulation of glucose utilization Diabetes. 31: 663-669. PMID 6761205 |
0.344 |
|
| 1982 |
Gottesman I, Mandarino L, Verdonk C, Rizza R, Gerich J. Insulin increases the maximum velocity for glucose uptake without altering the Michaelis constant in man. Evidence that insulin increases glucose uptake merely by providing additional transport sites Journal of Clinical Investigation. 70: 1310-1314. PMID 6757268 DOI: 10.1172/Jci110731 |
0.409 |
|
| 1981 |
Rizza RA, Mandarino LJ, Gerich JE. Mechanism and significance of insulin resistance in non-insulin-dependent diabetes mellitus Diabetes. 30: 990-995. PMID 7030834 |
0.338 |
|
| 1981 |
Rizza RA, Mandarino LJ, Gerich JE. Dose-response characteristics for effects of insulin on production and utilization of glucose in man The American Journal of Physiology. 240. PMID 7018254 |
0.327 |
|
| 1981 |
Rizza RA, Mandarino LJ, Gerich JE. Mechanisms of insulin resistance in man. Assessment using the insulin dose-response curve in conjunction with insulin-receptor binding The American Journal of Medicine. 70: 169-176. PMID 7006389 DOI: 10.1016/0002-9343(81)90423-X |
0.312 |
|
| 1981 |
Mandarino L, Stenner D, Blanchard W, Nissen S, Gerich J, Ling N, Brazeau P, Bohlen P, Esch F, Guillemin R. Selective effects of somatostatin-14, -25 and -28 on in vitro insulin and glucagon secretion. Nature. 291: 76-7. PMID 6112710 DOI: 10.1038/291076A0 |
0.323 |
|
| 1980 |
Itoh M, Mandarino L, Gerich JE. Antisomatostatin gamma globulin augments secretion of both insulin and glucagon in vitro. Evidence for a physiologic role for endogenous somatostatin in the regulation of pancreatic A- and B-cell function Diabetes. 29: 693-696. PMID 6160072 DOI: 10.2337/Diab.29.9.693 |
0.402 |
|
| 1980 |
Mandarino L, Itoh M, Blanchard W, Patton G, Gerich J. Stimulation of insulin release in the absence of extracellular calcium by isobutylmethylxanthine and its inhibition by somatostatin Endocrinology. 106: 430-433. PMID 6153357 DOI: 10.1210/Endo-106-2-430 |
0.312 |
|
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