Robert A. Nichols - Publications

Affiliations: 
University of Hawaii, Honolulu, HI, United States 
Area:
Alzheimer's disease

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Arora K, Cheng J, Nichols RA. Nicotinic Acetylcholine Receptors Sensitize a MAPK-linked Toxicity Pathway on Prolonged Exposure to β-Amyloid. The Journal of Biological Chemistry. 290: 21409-20. PMID 26139609 DOI: 10.1074/jbc.M114.634162  1
2014 Lawrence JL, Tong M, Alfulaij N, Sherrin T, Contarino M, White MM, Bellinger FP, Todorovic C, Nichols RA. Regulation of presynaptic Ca2+, synaptic plasticity and contextual fear conditioning by a N-terminal β-amyloid fragment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14210-8. PMID 25339735 DOI: 10.1523/JNEUROSCI.0326-14.2014  1
2013 Arora K, Alfulaij N, Higa JK, Panee J, Nichols RA. Impact of sustained exposure to β-amyloid on calcium homeostasis and neuronal integrity in model nerve cell system expressing α4β2 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 288: 11175-90. PMID 23479730 DOI: 10.1074/jbc.M113.453746  1
2012 Pitts MW, Raman AV, Hashimoto AC, Todorovic C, Nichols RA, Berry MJ. Deletion of selenoprotein P results in impaired function of parvalbumin interneurons and alterations in fear learning and sensorimotor gating. Neuroscience. 208: 58-68. PMID 22640876 DOI: 10.1016/j.neuroscience.2012.02.017  1
2011 Nichols RA. Serotonin, presynaptic 5-HT₃ receptors and synaptic plasticity in the developing cerebellum. The Journal of Physiology. 589: 5019-20. PMID 22042545 DOI: 10.1113/jphysiol.2011.219782  1
2011 Tong M, Arora K, White MM, Nichols RA. Role of key aromatic residues in the ligand-binding domain of alpha7 nicotinic receptors in the agonist action of beta-amyloid. The Journal of Biological Chemistry. 286: 34373-81. PMID 21828053 DOI: 10.1074/jbc.M111.241299  1
2011 Yang K, Buhlman L, Khan GM, Nichols RA, Jin G, McIntosh JM, Whiteaker P, Lukas RJ, Wu J. Functional nicotinic acetylcholine receptors containing α6 subunits are on GABAergic neuronal boutons adherent to ventral tegmental area dopamine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2537-48. PMID 21325521 DOI: 10.1523/JNEUROSCI.3003-10.2011  1
2010 Khan GM, Tong M, Jhun M, Arora K, Nichols RA. beta-Amyloid activates presynaptic alpha7 nicotinic acetylcholine receptors reconstituted into a model nerve cell system: involvement of lipid rafts. The European Journal of Neuroscience. 31: 788-96. PMID 20374280 DOI: 10.1111/j.1460-9568.2010.07116.x  1
2009 Dougherty JJ, Nichols RA. Cross-regulation between colocalized nicotinic acetylcholine and 5-HT3 serotonin receptors on presynaptic nerve terminals. Acta Pharmacologica Sinica. 30: 788-94. PMID 19498419 DOI: 10.1038/aps.2009.62  1
2009 Mehta TK, Dougherty JJ, Wu J, Choi CH, Khan GM, Nichols RA. Defining pre-synaptic nicotinic receptors regulated by beta amyloid in mouse cortex and hippocampus with receptor null mutants. Journal of Neurochemistry. 109: 1452-8. PMID 19457164 DOI: 10.1111/j.1471-4159.2009.06070.x  1
2008 Dougherty JJ, Wu J, Mehta TK, Brown B, Nichols RA. Chronic nicotine alters nicotinic receptor-induced presynaptic Ca2+ responses in isolated nerve terminals. Neurochemical Research. 33: 1106-12. PMID 18095155 DOI: 10.1007/s11064-007-9557-9  1
2007 Wu J, Khan GM, Nichols RA. Dopamine release in prefrontal cortex in response to beta-amyloid activation of alpha7 * nicotinic receptors. Brain Research. 1182: 82-9. PMID 17935702 DOI: 10.1016/j.brainres.2007.08.079  1
2007 Nichols RA, Dengler AF, Nakagawa EM, Bashkin M, Paul BT, Wu J, Khan GM. A constitutive, transient receptor potential-like Ca2+ influx pathway in presynaptic nerve endings independent of voltage-gated Ca2+ channels and Na+/Ca2+ exchange. The Journal of Biological Chemistry. 282: 36102-11. PMID 17928293 DOI: 10.1074/jbc.M706002200  1
2006 Wu J, Dougherty JJ, Nichols RA. Dopamine receptor regulation of Ca2+ levels in individual isolated nerve terminals from rat striatum: comparison of presynaptic D1-like and D2-like receptors. Journal of Neurochemistry. 98: 481-94. PMID 16805841 DOI: 10.1111/j.1471-4159.2006.03901.x  1
2003 Dougherty JJ, Wu J, Nichols RA. Beta-amyloid regulation of presynaptic nicotinic receptors in rat hippocampus and neocortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 6740-7. PMID 12890766  1
2001 Nayak SV, Dougherty JJ, McIntosh JM, Nichols RA. Ca(2+) changes induced by different presynaptic nicotinic receptors in separate populations of individual striatal nerve terminals. Journal of Neurochemistry. 76: 1860-70. PMID 11259504 DOI: 10.1046/j.1471-4159.2001.00197.x  1
2001 Rondé P, Nichols RA. Postsynaptic target regulates functional responses induced by 5-HT3 serotonin receptors on axonal varicosities of NG108-15 hybrid neuroblastoma cells. Neuroscience. 102: 979-87. PMID 11182259 DOI: 10.1016/S0306-4522(00)00512-1  1
2000 Rondé P, Dougherty JJ, Nichols RA. Functional IP3- and ryanodine-sensitive calcium stores in presynaptic varicosities of NG108-15 (rodent neuroblastoma x glioma hybrid) cells. The Journal of Physiology. 529: 307-19. PMID 11101642 DOI: 10.1111/j.1469-7793.2000.00307.x  1
2000 Nayak SV, Rondé P, Spier AD, Lummis SC, Nichols RA. Nicotinic receptors co-localize with 5-HT(3) serotonin receptors on striatal nerve terminals. Neuropharmacology. 39: 2681-90. PMID 11044738 DOI: 10.1016/S0028-3908(00)00109-X  1
1999 Nayak SV, Rondé P, Spier AD, Lummis SC, Nichols RA. Calcium changes induced by presynaptic 5-hydroxytryptamine-3 serotonin receptors on isolated terminals from various regions of the rat brain. Neuroscience. 91: 107-17. PMID 10336063 DOI: 10.1016/S0306-4522(98)00520-X  1
1999 Spier AD, Wotherspoon G, Nayak SV, Nichols RA, Priestley JV, Lummis SC. Antibodies against the extracellular domain of the 5-HT3 receptor label both native and recombinant receptors. Brain Research. Molecular Brain Research. 67: 221-30. PMID 10216220 DOI: 10.1016/S0169-328X(99)00055-8  1
1998 Hou WF, Zhang SP, Davidkova G, Nichols RA, Weiss B. Effect of antisense oligodeoxynucleotides directed to individual calmodulin gene transcripts on the proliferation and differentiation of PC12 cells. Antisense & Nucleic Acid Drug Development. 8: 295-308. PMID 9743467  1
1998 Rondé P, Nichols RA. High calcium permeability of serotonin 5-HT3 receptors on presynaptic nerve terminals from rat striatum. Journal of Neurochemistry. 70: 1094-103. PMID 9489730  1
1997 Rondé P, Nichols RA. 5-HT3 receptors induce rises in cytosolic and nuclear calcium in NG108-15 cells via calcium-induced calcium release. Cell Calcium. 22: 357-65. PMID 9448942  1
1996 Davidkova G, Zhang SP, Nichols RA, Weiss B. Reduced level of calmodulin in PC12 cells induced by stable expression of calmodulin antisense RNA inhibits cell proliferation and induces neurite outgrowth. Neuroscience. 75: 1003-19. PMID 8938737 DOI: 10.1016/0306-4522(96)00230-8  1
1996 Nichols RA, Suplick GR. Rapid chelation of calcium entering isolated rat brain nerve terminals during stimulation inhibits neurotransmitter release. Neuroscience Letters. 211: 135-7. PMID 8830863 DOI: 10.1016/0304-3940(96)12728-2  1
1996 Nichols RA, Mollard P. Direct observation of serotonin 5-HT3 receptor-induced increases in calcium levels in individual brain nerve terminals. Journal of Neurochemistry. 67: 581-92. PMID 8764583  1
1995 Natsukari N, Zhang SP, Nichols RA, Weiss B. Immunocytochemical localization of calmodulin in PC12 cells and its possible interaction with histones. Neurochemistry International. 26: 465-76. PMID 7492944 DOI: 10.1016/0197-0186(94)00156-O  1
1993 Sihra TS, Nichols RA. Mechanisms in the regulation of neurotransmitter release from brain nerve terminals: current hypotheses. Neurochemical Research. 18: 47-58. PMID 8096629 DOI: 10.1007/BF00966922  1
1993 Sihra TS, Piomelli D, Nichols RA. Barium evokes glutamate release from rat brain synaptosomes by membrane depolarization: involvement of K+, Na+, and Ca2+ channels. Journal of Neurochemistry. 61: 1220-30. PMID 7690845  1
1992 Nichols RA, Chilcote TJ, Czernik AJ, Greengard P. Synapsin I regulates glutamate release from rat brain synaptosomes. Journal of Neurochemistry. 58: 783-5. PMID 1345942  0.6
1991 Han HQ, Nichols RA, Rubin MR, Bähler M, Greengard P. Induction of formation of presynaptic terminals in neuroblastoma cells by synapsin IIb. Nature. 349: 697-700. PMID 1899916 DOI: 10.1038/349697a0  0.6
1990 Nichols RA, Sihra TS, Czernik AJ, Nairn AC, Greengard P. Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes. Nature. 343: 647-51. PMID 2154695 DOI: 10.1038/343647a0  1
1989 Nichols RA, Chandler CE, Shooter EM. Enucleation of the rat pheochromocytoma clonal cell line, PC12: effect on neurite outgrowth. Journal of Cellular Physiology. 141: 301-9. PMID 2808539 DOI: 10.1002/jcp.1041410211  1
1989 Nichols RA, Wu WC, Haycock JW, Greengard P. Introduction of impermeant molecules into synaptosomes using freeze/thaw permeabilization. Journal of Neurochemistry. 52: 521-9. PMID 2536075  1
1987 Isackson PJ, Silverman RE, Blaber M, Server AC, Nichols RA, Shooter EM, Bradshaw RA. Epidermal growth factor binding protein: identification of a different protein. Biochemistry. 26: 2082-5. PMID 3304419  1
1987 Romano C, Nichols RA, Greengard P, Greene LA. Synapsin I in PC12 cells. I. Characterization of the phosphoprotein and effect of chronic NGF treatment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 1294-9. PMID 3106589  1
1987 Nichols RA, Haycock JW, Wang JK, Greengard P. Phorbol ester enhancement of neurotransmitter release from rat brain synaptosomes. Journal of Neurochemistry. 48: 615-21. PMID 3098922  1
1987 Romano C, Nichols RA, Greengard P. Synapsin I in PC12 cells. II. Evidence for regulation by NGF of phosphorylation at a novel site. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 1300-6. PMID 3033168  1
1987 Nairn AC, Nichols RA, Brady MJ, Palfrey HC. Nerve growth factor treatment or cAMP elevation reduces Ca2+/calmodulin-dependent protein kinase III activity in PC12 cells. The Journal of Biological Chemistry. 262: 14265-72. PMID 2443502  1
1985 Nichols RA, Shooter EM. Subunit interactions of the nerve and epidermal growth factor complexes: protection of the biological subunit from proteolytic modification. Developmental Neuroscience. 7: 216-29. PMID 3913581 DOI: 10.1159/000112290  1
1983 Nichols RA, Shooter EM. Characterization of the differential interaction of the microheterogeneous forms of the gamma subunit of 7 S nerve growth factor with natural and synthetic ligands. The Journal of Biological Chemistry. 258: 10296-303. PMID 6885782  1
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