| Year |
Citation |
Score |
| 2018 |
Kallander LS, Washburn D, Hilfiker MA, Eidam HS, Lawhorn BG, Prendergast J, Fox R, Dowdell S, Manns S, Hoang T, Zhao S, Ye G, Hammond M, Holt DA, Roethke T, ... ... Quinn AM, et al. Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1. Acs Medicinal Chemistry Letters. 9: 736-740. PMID 30034610 DOI: 10.1021/Acsmedchemlett.8B00173 |
0.327 |
|
| 2013 |
Wang L, Chang J, Varghese D, Dellinger M, Kumar S, Best AM, Ruiz J, Bruick R, Peña-Llopis S, Xu J, Babinski DJ, Frantz DE, Brekken RA, Quinn AM, Simeonov A, et al. A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Nature Communications. 4: 2035. PMID 23792809 DOI: 10.1038/Ncomms3035 |
0.368 |
|
| 2013 |
Wang L, Chang J, Varghese D, Dellinger M, Kumar S, Best AM, Ruiz J, Bruick R, Penã-Llopis S, Xu J, Babinski DJ, Frantz DE, Brekken RA, Quinn AM, Simeonov A, et al. Erratum: A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth Nature Communications. 4. DOI: 10.1038/Ncomms3639 |
0.34 |
|
| 2012 |
Lu Q, Quinn AM, Patel MP, Semus SF, Graves AP, Bandyopadhyay D, Pope AJ, Thrall SH. Perspectives on the discovery of small-molecule modulators for epigenetic processes. Journal of Biomolecular Screening. 17: 555-71. PMID 22392809 DOI: 10.1177/1087057112437763 |
0.311 |
|
| 2011 |
Quinn AM, Simeonov A. Methods for Activity Analysis of the Proteins that Regulate Histone Methylation. Current Chemical Genomics. 5: 95-105. PMID 21966349 DOI: 10.2174/1875397301005010095 |
0.384 |
|
| 2011 |
Shultz CA, Quinn AM, Park JH, Harvey RG, Bolton JL, Maser E, Penning TM. Specificity of human aldo-keto reductases, NAD(P)H:quinone oxidoreductase, and carbonyl reductases to redox-cycle polycyclic aromatic hydrocarbon diones and 4-hydroxyequilenin-o-quinone. Chemical Research in Toxicology. 24: 2153-66. PMID 21910479 DOI: 10.1021/Tx200294C |
0.47 |
|
| 2010 |
King ON, Li XS, Sakurai M, Kawamura A, Rose NR, Ng SS, Quinn AM, Rai G, Mott BT, Beswick P, Klose RJ, Oppermann U, Jadhav A, Heightman TD, Maloney DJ, et al. Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors. Plos One. 5: e15535. PMID 21124847 DOI: 10.1371/Journal.Pone.0015535 |
0.396 |
|
| 2010 |
Liu F, Chen X, Allali-Hassani A, Quinn AM, Wigle TJ, Wasney GA, Dong A, Senisterra G, Chau I, Siarheyeva A, Norris JL, Kireev DB, Jadhav A, Herold JM, Janzen WP, et al. Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines. Journal of Medicinal Chemistry. 53: 5844-57. PMID 20614940 DOI: 10.1021/Jm100478Y |
0.354 |
|
| 2010 |
Quinn AM, Allali-Hassani A, Vedadi M, Simeonov A. A chemiluminescence-based method for identification of histone lysine methyltransferase inhibitors. Molecular Biosystems. 6: 782-8. PMID 20567762 DOI: 10.1039/B921912A |
0.36 |
|
| 2010 |
Boxer MB, Quinn AM, Shen M, Jadhav A, Leister W, Simeonov A, Auld DS, Thomas CJ. A highly potent and selective caspase 1 inhibitor that utilizes a key 3-cyanopropanoic acid moiety. Chemmedchem. 5: 730-8. PMID 20229566 DOI: 10.1002/Cmdc.200900531 |
0.331 |
|
| 2010 |
Sakurai M, Rose NR, Schultz L, Quinn AM, Jadhav A, Ng SS, Oppermann U, Schofield CJ, Simeonov A. A miniaturized screen for inhibitors of Jumonji histone demethylases. Molecular Biosystems. 6: 357-64. PMID 20094655 DOI: 10.1039/B912993F |
0.334 |
|
| 2010 |
Quinn AM, Bedford MT, Espejo A, Spannhoff A, Austin CP, Oppermann U, Simeonov A. A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics. Nucleic Acids Research. 38: e11. PMID 19897549 DOI: 10.1093/Nar/Gkp899 |
0.315 |
|
| 2009 |
Liu F, Chen X, Allali-Hassani A, Quinn AM, Wasney GA, Dong A, Barsyte D, Kozieradzki I, Senisterra G, Chau I, Siarheyeva A, Kireev DB, Jadhav A, Herold JM, Frye SV, et al. Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a. Journal of Medicinal Chemistry. 52: 7950-3. PMID 19891491 DOI: 10.1021/Jm901543M |
0.31 |
|
| 2008 |
Quinn AM, Harvey RG, Penning TM. Oxidation of PAH trans-dihydrodiols by human aldo-keto reductase AKR1B10. Chemical Research in Toxicology. 21: 2207-15. PMID 18788756 DOI: 10.1021/Tx8002005 |
0.441 |
|
| 2008 |
Park JH, Mangal D, Tacka KA, Quinn AM, Harvey RG, Blair IA, Penning TM. Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 6846-51. PMID 18474869 DOI: 10.1073/Pnas.0802776105 |
0.493 |
|
| 2008 |
Quinn AM, Penning TM. Comparisons of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol activation by human cytochrome P450 and aldo-keto reductase enzymes: effect of redox state and expression levels. Chemical Research in Toxicology. 21: 1086-94. PMID 18402469 DOI: 10.1021/Tx700345V |
0.479 |
|
| 2005 |
Jiang H, Shen YM, Quinn AM, Penning TM. Competing roles of cytochrome P450 1A1/1B1 and aldo-keto reductase 1A1 in the metabolic activation of (+/-)-7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene in human bronchoalveolar cell extracts. Chemical Research in Toxicology. 18: 365-74. PMID 15720144 DOI: 10.1021/Tx0497245 |
0.427 |
|
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