Fred S. Gorelick - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Cell Biology, Computer Science

111 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Wang M, Gorelick FS. Ketamine and Xylazine Effects in Murine Model of Acute Pancreatitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 33881355 DOI: 10.1152/ajpgi.00023.2021  0.303
2020 Wang M, Phadke M, Packard D, Yadav D, Gorelick F. Zinc: Roles in pancreatic physiology and disease. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. PMID 32917512 DOI: 10.1016/J.Pan.2020.08.016  0.383
2020 Williams JA, Groblewski GE, Gorelick FS, Mayerle J, Apte M, Gukovskaya AS. American Pancreatic Association Frank Brooks Symposium: Fifty Years of Pancreatic Cell Biology. Pancreas. 49: 604-611. PMID 32433396 DOI: 10.1097/Mpa.0000000000001543  0.39
2020 Gorelick F, Nathanson MH. TRPV4 helps Piezo1 put the squeeze on pancreatic acinar cells. The Journal of Clinical Investigation. PMID 32281947 DOI: 10.1172/Jci136525  0.378
2020 Nair GKK, Yoo JW(, Gao Y, Desir G, Gorelick FS, Farrell JJ, Foster GG, Joshi N. Sa1154 ORGANOID-BASED PRECLINICAL MODELS RECAPITULATE RENALASE SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)31426-8  0.332
2020 Mareninova OA, Shalbueva N, Wightman CJ, Dillon DL, Davidson NO, Bensinger SJ, Gorelick FS, Dawson DW, Gukovsky I, Gukovskaya A. 838 DISORDERING OF ACINAR CELL CHOLESTEROL HOMEOSTASIS IN PANCREATITIS Gastroenterology. 158: S-168. DOI: 10.1016/S0016-5085(20)31108-2  0.333
2019 Lowe ME, Andersen DK, Caprioli RM, Choudhary J, Cruz-Monserrate Z, Dasyam AK, Forsmark CE, Gorelick FS, Gray JW, Haupt M, Kelly KA, Olive KP, Plevritis SK, Rappaport N, Roth HR, et al. Precision Medicine in Pancreatic Disease-Knowledge Gaps and Research Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop. Pancreas. 48: 1250-1258. PMID 31688587 DOI: 10.1097/Mpa.0000000000001412  0.3
2019 Malla SR, Krueger B, Wartmann T, Sendler M, Mahajan UM, Weiss FU, Thiel FG, De Boni C, Gorelick FS, Halangk W, Aghdassi AA, Reinheckel T, Gukovskaya AS, Lerch MM, Mayerle J. Early trypsin activation develops independently of autophagy in caerulein-induced pancreatitis in mice. Cellular and Molecular Life Sciences : Cmls. PMID 31363815 DOI: 10.1007/S00018-019-03254-7  0.405
2019 Saloman JL, Albers KM, Cruz-Monserrate Z, Davis BM, Edderkaoui M, Eibl G, Epouhe AY, Gedeon JY, Gorelick FS, Grippo PJ, Groblewski GE, Husain SZ, Lai KKY, Pandol SJ, Uc A, et al. Animal Models: Challenges and Opportunities to Determine Optimal Experimental Models of Pancreatitis and Pancreatic Cancer. Pancreas. 48: 759-779. PMID 31206467 DOI: 10.1097/Mpa.0000000000001335  0.345
2019 Gukovskaya AS, Gorelick FS, Groblewski GE, Mareninova OA, Lugea A, Antonucci L, Waldron RT, Habtezion A, Karin M, Pandol SJ, Gukovsky I. Recent Insights Into the Pathogenic Mechanism of Pancreatitis: Role of Acinar Cell Organelle Disorders. Pancreas. 48: 459-470. PMID 30973461 DOI: 10.1097/Mpa.0000000000001298  0.436
2018 Alahmari AA, Sreekumar B, Patel V, Ashat M, Alexandre M, Uduman AK, Akinbiyi EO, Ceplenski A, Shugrue CA, Kolodecik TR, Tashkandi N, Messenger SW, Groblewski GE, Gorelick FS, Thrower EC. Cigarette toxin 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces experimental pancreatitis through α7 nicotinic acetylcholine receptors (nAChRs) in mice. Plos One. 13: e0197362. PMID 29870540 DOI: 10.1371/Journal.Pone.0197362  0.378
2017 Biczo G, Vegh ET, Shalbueva N, Mareninova OA, Elperin J, Lotshaw E, Gretler S, Lugea A, Malla SR, Dawson D, Ruchala P, Whitelegge J, French SW, Wen L, Husain SZ, ... Gorelick FS, et al. Mitochondrial dysfunction, through impaired autophagy, leads to endoplasmic reticulum stress, deregulated lipid metabolism, and pancreatitis in animal models. Gastroenterology. PMID 29074451 DOI: 10.1053/J.Gastro.2017.10.012  0.34
2017 Kolodecik TR, Reed AM, Date K, Shugrue C, Patel V, Chung SL, Desir GV, Gorelick FS. The Serum Protein Renalase Reduces Injury in Experimental Pancreatitis. The Journal of Biological Chemistry. PMID 29042438 DOI: 10.1074/Jbc.M117.789776  0.416
2017 Lugea A, Waldron RT, Mareninova OA, Shalbueva N, Deng N, Su HY, Thomas DD, Jones EK, Messenger SW, Yang J, Hu C, Gukovsky I, Liu Z, Groblewski GE, Gukovskaya AS, ... Gorelick FS, et al. Human pancreatic acinar cells: proteomic characterization, physiologic responses, and organellar disorders in ex vivo pancreatitis. The American Journal of Pathology. PMID 28935577 DOI: 10.1016/J.Ajpath.2017.08.017  0.386
2017 Gorelick FS, Lerch MM. Do Animal Models of Acute Pancreatitis Reproduce Human Disease? Cellular and Molecular Gastroenterology and Hepatology. 4: 251-262. PMID 28752114 DOI: 10.1016/J.Jcmgh.2017.05.007  0.329
2017 Sheth SG, Conwell DL, Whitcomb DC, Alsante M, Anderson MA, Barkin J, Brand R, Cote GA, Freedman SD, Gelrud A, Gorelick F, Lee LS, Morgan K, Pandol S, Singh VK, et al. Academic Pancreas Centers of Excellence: Guidance from a multidisciplinary chronic pancreatitis working group at PancreasFest. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. PMID 28268158 DOI: 10.1016/J.Pan.2017.02.015  0.338
2016 Chung C, Gorelick FS. Targeting αv Integrins in Pancreatic Fibrosis: Progress in Resolving the Scar. Cellular and Molecular Gastroenterology and Hepatology. 2: 405-406. PMID 28090563 DOI: 10.1016/J.Jcmgh.2016.05.002  0.325
2016 Srinivasan P, Thrower EC, Gorelick FS, Said HM. Inhibition of Pancreatic Acinar Mitochondrial Thiamin Pyrophosphate Uptake by the Cigarette Smoke Component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00461.2015. PMID 26999808 DOI: 10.1152/Ajpgi.00461.2015  0.321
2016 Guo X, Hollander L, MacPherson D, Wang L, Velazquez H, Chang J, Safirstein R, Cha C, Gorelick F, Desir GV. Inhibition of renalase expression and signaling has antitumor activity in pancreatic cancer. Scientific Reports. 6: 22996. PMID 26972355 DOI: 10.1038/Srep22996  0.361
2015 Srinivasan P, Thrower EC, Loganathan G, Balamurugan AN, Subramanian VS, Gorelick FS, Said HM. Chronic Nicotine Exposure In Vivo and In Vitro Inhibits Vitamin B1 (Thiamin) Uptake by Pancreatic Acinar Cells. Plos One. 10: e0143575. PMID 26633299 DOI: 10.1371/Journal.Pone.0143575  0.305
2015 Messenger SW, Thomas DD, Cooley MM, Jones EK, Falkowski MA, August BK, Fernandez LA, Gorelick FS, Groblewski GE. Early to Late Endosome Trafficking Controls Secretion and Zymogen Activation in Rodent and Human Pancreatic Acinar Cells. Cellular and Molecular Gastroenterology and Hepatology. 1: 695-709. PMID 26618189 DOI: 10.1016/J.Jcmgh.2015.08.002  0.409
2015 Afghani E, Pandol SJ, Shimosegawa T, Sutton R, Wu BU, Vege SS, Gorelick F, Hirota M, Windsor J, Lo SK, Freeman ML, Lerch MM, Tsuji Y, Melmed GY, Wassef W, et al. Acute Pancreatitis-Progress and Challenges: A Report on an International Symposium. Pancreas. 44: 1195-210. PMID 26465949 DOI: 10.1097/Mpa.0000000000000500  0.369
2015 Foglio EJ, Gorelick F. Abdominal Paracentesis Drainage: Which Patients With Severe Acute Pancreatitis Will Benefit? Journal of Clinical Gastroenterology. 49: 717-719. PMID 26207360 DOI: 10.1097/Mcg.0000000000000387  0.358
2014 Reed AM, Kolodecik T, Husain SZ, Gorelick FS. Low pH enhances connexin32 degradation in the pancreatic acinar cell. American Journal of Physiology. Gastrointestinal and Liver Physiology. 307: G24-32. PMID 24812055 DOI: 10.1152/Ajpgi.00010.2014  0.313
2014 Reed A, Kolodecik TR, Gorelick FS. Su1900 Renalase Deficiency Worsens Acute Pancreatitis in Mice Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)61789-3  0.332
2013 Messenger SW, Thomas DD, Falkowski MA, Byrne JA, Gorelick FS, Groblewski GE. Tumor protein D52 controls trafficking of an apical endolysosomal secretory pathway in pancreatic acinar cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G439-52. PMID 23868405 DOI: 10.1152/Ajpgi.00143.2013  0.359
2013 Lerch MM, Gorelick FS. Models of acute and chronic pancreatitis. Gastroenterology. 144: 1180-93. PMID 23622127 DOI: 10.1053/J.Gastro.2012.12.043  0.375
2012 Kolodecik TR, Shugrue CA, Thrower EC, Levin LR, Buck J, Gorelick FS. Activation of soluble adenylyl cyclase protects against secretagogue stimulated zymogen activation in rat pancreaic acinar cells. Plos One. 7: e41320. PMID 22844459 DOI: 10.1371/Journal.Pone.0041320  0.428
2012 Alexandre M, Uduman AK, Minervini S, Raoof A, Shugrue CA, Akinbiyi EO, Patel V, Shitia M, Kolodecik TR, Patton R, Gorelick FS, Thrower EC. Tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone initiates and enhances pancreatitis responses. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G696-704. PMID 22837343 DOI: 10.1152/Ajpgi.00138.2012  0.372
2012 Shugrue CA, Alexandre M, Diaz de Villalvilla A, Kolodecik TR, Young LH, Gorelick FS, Thrower EC. Cerulein hyperstimulation decreases AMP-activated protein kinase levels at the site of maximal zymogen activation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G723-32. PMID 22821946 DOI: 10.1152/Ajpgi.00082.2012  0.421
2012 Hoque R, Malik AF, Gorelick F, Mehal WZ. Sterile inflammatory response in acute pancreatitis. Pancreas. 41: 353-357. PMID 22415665 DOI: 10.1097/Mpa.0B013E3182321500  0.356
2012 Alexandre M, Uduman AK, Shugrue C, Kolodecik T, Akinbiyi E, Gorelick FS, Thrower EC. 83 The Tobacco Toxin NNK Initiates and Sensitizes Acute Pancreatitis Responses In Vivo Gastroenterology. 142: S-20. DOI: 10.1016/S0016-5085(12)60078-X  0.362
2011 Alexandre M, Pandol SJ, Gorelick FS, Thrower EC. The emerging role of smoking in the development of pancreatitis. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. 11: 469-74. PMID 21986098 DOI: 10.1159/000332196  0.32
2011 Pandol SJ, Gorelick FS, Lugea A. Environmental and genetic stressors and the unfolded protein response in exocrine pancreatic function - a hypothesis. Frontiers in Physiology. 2: 8. PMID 21483727 DOI: 10.3389/Fphys.2011.00008  0.316
2011 Hoque R, Sohail M, Malik A, Sarwar S, Luo Y, Shah A, Barrat F, Flavell R, Gorelick F, Husain S, Mehal W. TLR9 and the NLRP3 Inflammasome Link Acinar Cell Death With Inflammation in Acute Pancreatitis Gastroenterology. 141: 358-369. PMID 21439959 DOI: 10.1053/J.Gastro.2011.03.041  0.397
2011 Chung C, Mader CC, Schmitz JC, Atladottir J, Fitchev P, Cornwell ML, Koleske AJ, Crawford SE, Gorelick F. The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer. Laboratory Investigation; a Journal of Technical Methods and Pathology. 91: 732-43. PMID 21339745 DOI: 10.1038/Labinvest.2011.8  0.314
2011 Pandol SJ, Lugea A, Mareninova OA, Smoot D, Gorelick FS, Gukovskaya AS, Gukovsky I. Investigating the pathobiology of alcoholic pancreatitis. Alcoholism, Clinical and Experimental Research. 35: 830-7. PMID 21284675 DOI: 10.1111/J.1530-0277.2010.01408.X  0.312
2011 Lugea A, Tischler D, Nguyen J, Gong J, Gukovsky I, French SW, Gorelick FS, Pandol SJ. Adaptive unfolded protein response attenuates alcohol-induced pancreatic damage. Gastroenterology. 140: 987-97. PMID 21111739 DOI: 10.1053/J.Gastro.2010.11.038  0.329
2011 Reed AM, Husain SZ, Thrower E, Alexandre M, Shah A, Gorelick FS, Nathanson MH. Low extracellular pH induces damage in the pancreatic acinar cell by enhancing calcium signaling. The Journal of Biological Chemistry. 286: 1919-26. PMID 21084290 DOI: 10.1074/Jbc.M110.158329  0.389
2011 Alexandre M, Minervini SN, Patel V, Uduman A, Shugrue C, Gorelick FS, Thrower EC. Tobacco Carcinogen NNK (4-[Methylnitrosamino]-1-[3-Pyridyl]-1-Butanone) Initiates and Sensitizes Acute Pancreatitis Responses Gastroenterology. 140: S-387. DOI: 10.1016/S0016-5085(11)61584-9  0.353
2011 Reed A, Husain SZ, Gorelick FS, Nathanson MH. Low pH Inhibits Gap Junction Communication in the Pancreatic Acinar Cell Gastroenterology. 140: S-385. DOI: 10.1016/S0016-5085(11)61577-1  0.313
2010 Pandol SJ, Gorelick FS, Gerloff A, Lugea A. Alcohol abuse, endoplasmic reticulum stress and pancreatitis. Digestive Diseases (Basel, Switzerland). 28: 776-82. PMID 21525762 DOI: 10.1159/000327212  0.364
2010 Thrower EC, Gorelick FS, Husain SZ. Molecular and cellular mechanisms of pancreatic injury. Current Opinion in Gastroenterology. 26: 484-9. PMID 20651589 DOI: 10.1097/Mog.0B013E32833D119E  0.355
2010 Atladottir J, Bhoomagoud M, Thrower EC, Shugrue C, Gorelick FS. T1949 Lactate Sensitizes to Pancreatitis Responses in Rats Gastroenterology. 138: S-893. DOI: 10.1016/S0016-5085(10)64126-1  0.307
2010 Chaudhuri A, Shah AU, Husain SZ, Gorelick FS, Nathanson MH. T1935 Low pH Enhances Calcium Signaling in the Pancreatic Acinar Cell Gastroenterology. 138: S-610. DOI: 10.1016/S0016-5085(10)62812-0  0.33
2010 Collaco A, Jakab RL, Gorelick FS, Ameen N. T1837 The Vacuolar ATPase Associates With CFTR in Apical Endocytic and Recycling Vesicles and Undergoes cAMP Regulated Trafficking in Intestinal Epithelial Cells Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)62715-1  0.303
2009 Gorelick FS, Thrower E. The acinar cell and early pancreatitis responses. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 7: S10-4. PMID 19896090 DOI: 10.1016/J.Cgh.2009.07.036  0.438
2009 Mareninova OA, Hermann K, French SW, O'Konski MS, Pandol SJ, Webster P, Erickson AH, Katunuma N, Gorelick FS, Gukovsky I, Gukovskaya AS. Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis. The Journal of Clinical Investigation. 119: 3340-55. PMID 19805911 DOI: 10.1172/Jci69660  0.466
2009 Thrower EC, Wang J, Cheriyan S, Lugea A, Kolodecik TR, Yuan J, Reeve JR, Gorelick FS, Pandol SJ. Protein kinase C delta-mediated processes in cholecystokinin-8-stimulated pancreatic acini. Pancreas. 38: 930-5. PMID 19752773 DOI: 10.1097/Mpa.0B013E3181B8476A  0.343
2009 Bhoomagoud M, Jung T, Atladottir J, Kolodecik TR, Shugrue C, Chaudhuri A, Thrower EC, Gorelick FS. Reducing extracellular pH sensitizes the acinar cell to secretagogue-induced pancreatitis responses in rats. Gastroenterology. 137: 1083-92. PMID 19454288 DOI: 10.1053/J.Gastro.2009.05.041  0.424
2009 Gaisano HY, Gorelick FS. New insights into the mechanisms of pancreatitis. Gastroenterology. 136: 2040-4. PMID 19379751 DOI: 10.1053/J.Gastro.2009.04.023  0.418
2009 Mareninova OA, Lee MA, Yakubov I, Pandol SJ, French SW, Gorelick FS, Gukovsky I, Gukovskaya AS. T1813 Autophagy Impairment As a Mechanism for Acute Pancreatitis: the Role of Cathepsins Gastroenterology. 136: A-585. DOI: 10.1016/S0016-5085(09)62694-9  0.345
2008 Thrower E, Husain S, Gorelick F. Molecular basis for pancreatitis. Current Opinion in Gastroenterology. 24: 580-5. PMID 19122498 DOI: 10.1097/Mog.0B013E32830B10E6  0.373
2008 Nagar AB, Gorelick F. Prevention of post-ERCP pancreatitis: a little antacid might go a long way. Gut. 57: 1492-3. PMID 18941003 DOI: 10.1136/Gut.2008.157289  0.388
2008 Thrower EC, Osgood S, Shugrue CA, Kolodecik TR, Chaudhuri AM, Reeve JR, Pandol SJ, Gorelick FS. The novel protein kinase C isoforms -delta and -epsilon modulate caerulein-induced zymogen activation in pancreatic acinar cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G1344-53. PMID 18388183 DOI: 10.1152/Ajpgi.00020.2008  0.435
2008 Gorelick F, Pandol S, Thrower E. Protein kinase C in the pancreatic acinar cell. Journal of Gastroenterology and Hepatology. 23: S37-41. PMID 18336661 DOI: 10.1111/J.1440-1746.2007.05282.X  0.463
2008 Mareninova OA, Hermann K, Pandol SJ, Webster P, French SW, Gorelick FS, Gukovsky I, Gukovskaya AS. M1828 Autophagy Impairment Mediates Vacuolization and Trypsinogen Activation in Experimental Pancreatitis Gastroenterology. 134: A-428. DOI: 10.1016/S0016-5085(08)62000-4  0.353
2007 Gorelick F. Pancreatic protease-activated receptors: friend and foe Gut. 56: 901-902. PMID 17566024 DOI: 10.1136/Gut.2006.111245  0.426
2007 Husain SZ, Grant WM, Gorelick FS, Nathanson MH, Shah AU. Caerulein-induced intracellular pancreatic zymogen activation is dependent on calcineurin. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G1594-9. PMID 17332472 DOI: 10.1152/Ajpgi.00500.2006  0.453
2007 Chaudhuri A, Husain SZ, Kolodecik TR, Grant WM, Gorelick FS. Cyclic AMP-dependent protein kinase and Epac mediate cyclic AMP responses in pancreatic acini. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G1403-10. PMID 17234888 DOI: 10.1152/Ajpgi.00478.2005  0.406
2007 Osgood S, Kolodecik TR, Reeve J, Pandol SJ, Gorelick FS, Thrower EC. DIFFERENTIAL ROLES OF PROTEIN KINASE C ISOFORMS IN ACUTE PANCREATITIS. Pancreas. 35: 420. DOI: 10.1097/01.Mpa.0000297761.67208.E3  0.362
2006 Gorelick FS, Shugrue CA, Kolodecik TR, Thrower EC. Vacuolar adenosine triphosphatase and pancreatic acinar cell function. Journal of Gastroenterology and Hepatology. 21: S18-21. PMID 16958663 DOI: 10.1111/J.1440-1746.2006.04576.X  0.394
2006 Cai D, Zhong M, Wang R, Netzer WJ, Shields D, Zheng H, Sisodia SS, Foster DA, Gorelick FS, Xu H, Greengard P. Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons. Proceedings of the National Academy of Sciences of the United States of America. 103: 1936-40. PMID 16449385 DOI: 10.1073/Pnas.0510710103  0.309
2006 Thrower EC, Diaz de Villalvilla AP, Kolodecik TR, Gorelick FS. Zymogen activation in a reconstituted pancreatic acinar cell system. American Journal of Physiology. Gastrointestinal and Liver Physiology. 290: G894-902. PMID 16339296 DOI: 10.1152/Ajpgi.00373.2005  0.406
2006 Otani T, Matsukura A, Takamoto T, Seyama Y, Shimizu Y, Shinomiya M, Usui H, Gorelick FS, Makuuchi M. Effects of pancreatic duct ligation on pancreatic response to bombesin. American Journal of Physiology. Gastrointestinal and Liver Physiology. 290: G633-9. PMID 16293654 DOI: 10.1152/Ajpgi.00377.2005  0.455
2006 Thrower E, Kolodecik T, Cooma-Ramberan I, Gorelick F. ALCOHOLS ENHANCE VACUOLAR ATPase TRANSLOCATION AND ZYMOGEN ACTIVATION IN CAERULEIN-STIMULATED PANCREATIC ACINAR CELLS Pancreas. 33: 502. DOI: 10.1097/00006676-200611000-00220  0.367
2005 Husain SZ, Prasad P, Grant WM, Kolodecik TR, Nathanson MH, Gorelick FS. The ryanodine receptor mediates early zymogen activation in pancreatitis. Proceedings of the National Academy of Sciences of the United States of America. 102: 14386-91. PMID 16186498 DOI: 10.1073/Pnas.0503215102  0.383
2005 Waterford SD, Kolodecik TR, Thrower EC, Gorelick FS. Vacuolar ATPase regulates zymogen activation in pancreatic acini. The Journal of Biological Chemistry. 280: 5430-4. PMID 15582989 DOI: 10.1074/Jbc.M413513200  0.4
2005 Chaudhuri A, Kolodecik TR, Gorelick FS. Effects of increased intracellular cAMP on carbachol-stimulated zymogen activation, secretion, and injury in the pancreatic acinar cell American Journal of Physiology - Gastrointestinal and Liver Physiology. 288. PMID 15458924 DOI: 10.1152/Ajpgi.00334.2004  0.416
2005 Husain S, Grant W, Kolodecik T, Nathanson MH, Gorelick FS. DISTINCT CALCIUM SIGNALS REGULATE PANCREATIC ZYMOGEN ACTIVATION Pancreas. 31: 446-447. DOI: 10.1097/01.Mpa.0000193686.75459.3A  0.36
2003 Gorelick FS. Alcohol and zymogen activation in the pancreatic acinar cell. Pancreas. 27: 305-10. PMID 14576492 DOI: 10.1097/00006676-200311000-00006  0.375
2003 Lu Z, Kolodecik TR, Karne S, Nyce M, Gorelick F. Effect of ligands that increase cAMP on caerulein-induced zymogen activation in pancreatic acini. American Journal of Physiology-Gastrointestinal and Liver Physiology. 285. PMID 12881228 DOI: 10.1152/Ajpgi.00213.2003  0.411
2003 Gorelick FS. Pancreas cell physiology and pancreatitis cell biology. Summary of a symposium held at the joint meeting of the EPC and the IAP, Heidelberg 2002. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. 3: 207-8. PMID 12771516 DOI: 10.1159/000070730  0.418
2003 Siddiqi SA, Gorelick FS, Mahan JT, Mansbach CM. COPII proteins are required for Golgi fusion but not for endoplasmic reticulum budding of the pre-chylomicron transport vesicle. Journal of Cell Science. 116: 415-27. PMID 12482926 DOI: 10.1242/Jcs.00215  0.312
2003 Matsukura A, Otani T, Seyama Y, Makuuchi M, Gorelick FS. Serine protease inhibitor prevents f-actin distribution in rat pancreatic acinar cells induced by cerulein hyperstimulation Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)82548-9  0.327
2003 Kolodecik T, Lu Z, Nyce M, Gorelick F. Cyclic AMP agonists sensitize isolated rat pancreatic acini to cerulein induced zymogen activation Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)81345-8  0.358
2002 Gukovskaya AS, Vaquero E, Zaninovic V, Gorelick FS, Lusis AJ, Brennan ML, Holland S, Pandol SJ. Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis. Gastroenterology. 122: 974-84. PMID 11910350 DOI: 10.1053/Gast.2002.32409  0.422
2002 Lu Z, Karne S, Kolodecik T, Gorelick FS. Alcohols enhance caerulein-induced zymogen activation in pancreatic acinar cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 282: G501-7. PMID 11842000 DOI: 10.1152/Ajpgi.00388.2001  0.361
2001 Otani T, Shimizu Y, Sugiki T, Ozawa F, Matsukura A, Takamoto T, Shinozaki H, Takeuchi A, Usui H, Makuuchi M, Kame S, Gorelick FS. Pancreatic duct ligated rat under bombesin stimulation causes TAP generation and cytoskeleton disassembly Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)82682-0  0.35
2000 Otani T, Gorelick FS. Cytoplasmic vacuole generation in rat isolated pancreatic acini under secretagogue hyperstimulation is associated with intracellular acidification Pancreas. 21: 105-107. PMID 10881943 DOI: 10.1097/00006676-200007000-00062  0.342
2000 Lerch MM, Gorelick FS. Early trypsinogen activation in acute pancreatitis Medical Clinics of North America. 84: 549-563. PMID 10872413 DOI: 10.1016/S0025-7125(05)70239-X  0.41
2000 C JA, Tandon M, Alaparthi L, Gorelick F. Octreotide LAR as adjuvant treatment for pancreatic ascites The American Journal of Gastroenterology. 95: 2619-2619. DOI: 10.1111/J.1572-0241.2000.03077.X  0.378
2000 Otani T, Matsukura A, Takamoto T, Usui H, Shimizu Y, Sugiki T, Makuuchi M, Karne S, Kolodecik TR, Gorelick FS. Tap generation in isolated pancreatic acini under bombesin stimulation Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)82706-7  0.341
1999 Gorelick FS, Otani T. Mechanisms of intracellular zymogen activation Bailliere's Best Practice in Clinical Gastroenterology. 13: 227-240. PMID 11030603 DOI: 10.1053/Bega.1999.0021  0.445
1999 Karne S, Gorelick FS. Etiopathogenesis of acute pancreatitis Surgical Clinics of North America. 79: 699-710. PMID 10470320 DOI: 10.1016/S0039-6109(05)70036-0  0.415
1998 Grady T, Mah'moud M, Otani T, Rhee S, Lerch MM, Gorelick FS. Zymogen proteolysis within the pancreatic acinar cell is associated with cellular injury American Journal of Physiology - Gastrointestinal and Liver Physiology. 275. PMID 9815031 DOI: 10.1152/Ajpgi.1998.275.5.G1010  0.387
1998 Otani T, Chepilko SM, Grendell JH, Gorelick FS. Codistribution of TAP and the granule membrane protein GRAMP-92 in rat caerulein-induced pancreatitis American Journal of Physiology - Gastrointestinal and Liver Physiology. 275. PMID 9815030 DOI: 10.1152/Ajpgi.1998.275.5.G999  0.438
1998 Matovcik LM, Nairn AC, Gorelick FS. Cellular localization of calmodulin-dependent protein kinases I and II to A-cells and D-cells of the endocrine pancreas. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 46: 519-26. PMID 9524198 DOI: 10.1177/002215549804600412  0.333
1997 Otani T, Atomi Y, Kuroda A, Muto T, Tamura M, Fukuda S, Akao S, Gorelick FS. Distribution of a synthetic protease inhibitor in rat pancreatic acini after supramaximal secretagogue stimulation Pancreas. 14: 142-149. PMID 9057186 DOI: 10.1097/00006676-199703000-00006  0.367
1996 Matovcik LM, Maranto AR, Soroka CJ, Gorelick FS, Smith J, Goldenring JR. Co-distribution of calmodulin-dependent protein kinase II and inositol trisphosphate receptors in an apical domain of gastrointestinal mucosal cells Journal of Histochemistry and Cytochemistry. 44: 1243-1250. PMID 8918899 DOI: 10.1177/44.11.8918899  0.309
1995 Gorelick FS, Matovcik LM. Lysosomal enzymes and pancreatitis Gastroenterology. 109: 620-625. PMID 7615215 DOI: 10.1016/0016-5085(95)90355-0  0.35
1995 Fallon MB, Gorelick FS, Anderson JM, Mennone A, Saluja A, Steer ML. Effect of cerulein hyperstimulation on the paracellular barrier of rat exocrine pancreas Gastroenterology. 108: 1863-1872. PMID 7539388 DOI: 10.1016/0016-5085(95)90151-5  0.407
1994 Cui ZJ, Gorelick FS, Dannies PS. Calcium/calmodulin-dependent protein kinase-II activation in rat pituitary cells in the presence of thyrotropin-releasing hormone and dopamine Endocrinology. 134: 2245-2250. PMID 8156928 DOI: 10.1210/Endo.134.5.8156928  0.326
1994 Ogden JM, Modlin IM, Gorelick FS, Marks IN. Effect of buprenorphine on pancreatic enzyme synthesis and secretion in normal rats and rats with acute edematous pancreatitis. Digestive Diseases and Sciences. 39: 2407-15. PMID 7525167 DOI: 10.1007/Bf02087658  0.405
1994 Gorelick FS. Pancreatic diseases: Editorial overview Current Opinion in Gastroenterology. 10: 481-484. DOI: 10.1097/00001574-199409000-00001  0.357
1993 Matovcik LM, Haimowitz B, Goldenring JR, Czernik AJ, Gorelick FS. Distribution of calcium/calmodulin-dependent protein kinase II in rat ileal enterocytes American Journal of Physiology - Cell Physiology. 264. PMID 8386447 DOI: 10.1152/Ajpcell.1993.264.4.C1029  0.315
1993 Marino CR, Leach SD, Schaefer JF, Miller LJ, Gorelick FS. Characterization of cAMP-dependent protein kinase activation by CCK in rat pancreas Febs Letters. 316: 48-52. PMID 7678554 DOI: 10.1016/0014-5793(93)81734-H  0.359
1993 Leach SD, Bilchik AJ, Karapetian O, Gorelick FS, Modlin IM. Influence of chloroquine on diet-induced pancreatitis Pancreas. 8: 64-69. PMID 7678327 DOI: 10.1097/00006676-199301000-00013  0.37
1992 Leach SD, Gorelick FS, Modlin IM. New perspectives on acute pancreatitis Scandinavian Journal of Gastroenterology. 27: 29-38. PMID 1439566 DOI: 10.3109/00365529209095976  0.37
1992 Gorelick FS. Pancreatic acinar cell pathophysiology Yale Journal of Biology and Medicine. 65: 437-440.  0.307
1991 Leach SD, Modlin IM, Scheele GA, Gorelick FS. Intracellular activation of digestive zymogens in rat pancreatic acini stimulation by high doses of cholecystokinin Journal of Clinical Investigation. 87: 362-366. PMID 1985109 DOI: 10.1172/Jci114995  0.382
1991 Marino CR, Matovcik LM, Gorelick FS, Cohn JA. Localization of the cystic fibrosis transmembrane conductance regulator in pancreas Journal of Clinical Investigation. 88: 712-716. PMID 1713921 DOI: 10.1172/Jci115358  0.342
1990 Leach SD, Gorelick FS, Modlin IM. Acute pancreatitis at its Centenary: The contribution of Reginald Fitz Annals of Surgery. 212: 109-113. PMID 2194439 DOI: 10.1097/00000658-199007000-00014  0.394
1990 Cohen ME, Reinlib L, Watson AJ, Gorelick F, Rys-Sikora K, Tse M, Rood RP, Czernik AJ, Sharp GW, Donowitz M. Rabbit ileal villus cell brush border Na+/H+ exchange is regulated by Ca2+/calmodulin-dependent protein kinase II, a brush border membrane protein. Proceedings of the National Academy of Sciences of the United States of America. 87: 8990-4. PMID 2174171 DOI: 10.1073/Pnas.87.22.8990  0.302
1990 Marino CR, Castle JD, Gorelick FS. Regulated phosphorylation of secretory granule membrane proteins of the rat parotid gland. The American Journal of Physiology. 259: G70-7. PMID 1695488 DOI: 10.1152/Ajpgi.1990.259.1.G70  0.319
1988 Jamieson JD, Gorelick FS, Chang A. Development of secretagogue responsiveness in the pancreas Scandinavian Journal of Gastroenterology. 23: 98-103. PMID 2852401 DOI: 10.3109/00365528809095920  0.388
1987 Gorelick FS, Chang A, Jamieson JD. Calcium-calmodulin-stimulated protein kinase in developing pancreas American Journal of Physiology - Gastrointestinal and Liver Physiology. 253. PMID 3116856 DOI: 10.1152/Ajpgi.1987.253.4.G469  0.363
1987 Cohn JA, Kinder B, Jamieson JD, Delahunt NG, Gorelick FS. Purification and properties of a multifunctional calcium/calmodulin-dependent protein kinase from rat pancreas Bba - Molecular Cell Research. 928: 320-331. PMID 3105599 DOI: 10.1016/0167-4889(87)90192-3  0.315
1987 Kinder BK, Delahunt NG, Jamieson JD, Gorelick FS. Calcium-calmodulin-dependent protein kinase in hyperplastic human parathyroid glands Endocrinology. 120: 170-177. PMID 3096699 DOI: 10.1210/Endo-120-1-170  0.309
1983 Gorelick FS, Cohn JA, Freedman SD, Delahunt NG, Gershoni JM, Jamieson JD. Calmodulin-stimulated protein kinase activity from rat pancreas Journal of Cell Biology. 97: 1294-1298. PMID 6619194 DOI: 10.1083/Jcb.97.4.1294  0.302
1980 Schultz GS, Sarras MP, Gunther GR, Hull BE, Alicea HA, Gorelick FS, Jamieson JD. Guinea pig pancreatic acini prepared with purified collagenase Experimental Cell Research. 130: 49-62. PMID 6256185 DOI: 10.1016/0014-4827(80)90041-5  0.385
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