Fred H. (Rusty) Gage - Publications

Affiliations: 
Salk Institute for Biological Studies, La Jolla, CA, United States 
 University of California, San Diego, La Jolla, CA 
Area:
Plasticity
Website:
http://logg.salk.edu/index.php

321 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Marchetto MC, Hrvoj-Mihic B, Kerman BE, Yu DX, Vadodaria KC, Linker SB, Narvaiza I, Santos R, Denli AM, Mendes AP, Oefner R, Cook J, McHenry L, Grasmick JM, Heard K, ... ... Gage FH, et al. Species-specific maturation profiles of human, chimpanzee and bonobo neural cells. Elife. 8. PMID 30730291 DOI: 10.7554/eLife.37527  0.88
2019 Lucassen PJ, Toni N, Kempermann G, Frisen J, Gage FH, Swaab DF. Limits to human neurogenesis-really? Molecular Psychiatry. PMID 30617274 DOI: 10.1038/s41380-018-0337-5  1
2018 Padmanabhan K, Osakada F, Tarabrina A, Kizer E, Callaway EM, Gage FH, Sejnowski TJ. Centrifugal Inputs to the Main Olfactory Bulb Revealed Through Whole Brain Circuit-Mapping. Frontiers in Neuroanatomy. 12: 115. PMID 30666191 DOI: 10.3389/fnana.2018.00115  0.88
2018 Kim Y, Vadodaria KC, Lenkei Z, Kato T, Gage FH, Marchetto MC, Santos R. MITOCHONDRIA, METABOLISM AND REDOX MECHANISMS IN PSYCHIATRIC DISORDERS. Antioxidants & Redox Signaling. PMID 30585734 DOI: 10.1089/ars.2018.7606  0.84
2018 Suh H, Zhou QG, Fernandez-Carasa I, Clemenson GD, Pons-Espinal M, Ro EJ, Marti M, Raya A, Gage FH, Consiglio A. Long-Term Labeling of Hippocampal Neural Stem Cells by a Lentiviral Vector. Frontiers in Molecular Neuroscience. 11: 415. PMID 30498432 DOI: 10.3389/fnmol.2018.00415  1
2018 McCarthy MJ, Wei H, Nievergelt CM, Stautland A, Maihofer AX, Welsh DK, Shilling P, Alda M, Alliey-Rodriguez N, Anand A, Andreasson OA, Balaraman Y, Berrettini WH, Bertram H, Brennand KJ, ... ... Gage FH, et al. Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30487653 DOI: 10.1038/s41386-018-0273-8  0.44
2018 Kuhn HG, Toda T, Gage FH. Adult Hippocampal Neurogenesis: A Coming-of-Age Story. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 38: 10401-10410. PMID 30381404 DOI: 10.1523/JNEUROSCI.2144-18.2018  0.32
2018 Mertens J, Reid D, Lau S, Kim Y, Gage FH. Aging in a Dish: iPSC-Derived and Directly Induced Neurons for Studying Brain Aging and Age-Related Neurodegenerative Diseases. Annual Review of Genetics. PMID 30208291 DOI: 10.1146/annurev-genet-120417-031534  0.44
2018 Choi SH, Bylykbashi E, Chatila ZK, Lee SW, Pulli B, Clemenson GD, Kim E, Rompala A, Oram MK, Asselin C, Aronson J, Zhang C, Miller SJ, Lesinski A, Chen JW, ... ... Gage FH, et al. Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model. Science (New York, N.Y.). 361. PMID 30190379 DOI: 10.1126/science.aan8821  1
2018 Eftekharzadeh B, Daigle JG, Kapinos LE, Coyne A, Schiantarelli J, Carlomagno Y, Cook C, Miller SJ, Dujardin S, Amaral AS, Grima JC, Bennett RE, Tepper K, DeTure M, Vanderburgh CR, ... ... Gage FH, et al. Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease. Neuron. 99: 925-940.e7. PMID 30189209 DOI: 10.1016/j.neuron.2018.07.039  0.36
2018 van den Hurk M, Erwin JA, Yeo GW, Gage FH, Bardy C. Patch-Seq Protocol to Analyze the Electrophysiology, Morphology and Transcriptome of Whole Single Neurons Derived From Human Pluripotent Stem Cells. Frontiers in Molecular Neuroscience. 11: 261. PMID 30147644 DOI: 10.3389/fnmol.2018.00261  0.72
2018 Jaeger BN, Linker SB, Parylak SL, Barron JJ, Gallina IS, Saavedra CD, Fitzpatrick C, Lim CK, Schafer ST, Lacar B, Jessberger S, Gage FH. A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons. Nature Communications. 9: 3084. PMID 30082781 DOI: 10.1038/s41467-018-05418-8  0.76
2018 Mansour AA, Gonçalves JT, Bloyd CW, Li H, Fernandes S, Quang D, Johnston S, Parylak SL, Jin X, Gage FH. Erratum: An in vivo model of functional and vascularized human brain organoids. Nature Biotechnology. 36: 772. PMID 30080830 DOI: 10.1038/nbt0818-772e  0.76
2018 Linker SB, Hsu JY, Pfaff A, Amatya D, Ko SM, Voter S, Wong Q, Gage FH. BrainImageR: Spatiotemporal gene set analysis referencing the human brain. Bioinformatics (Oxford, England). PMID 30010719 DOI: 10.1093/bioinformatics/bty618  0.6
2018 Sommer A, Maxreiter F, Krach F, Fadler T, Grosch J, Maroni M, Graef D, Eberhardt E, Riemenschneider MJ, Yeo GW, Kohl Z, Xiang W, Gage FH, Winkler J, Prots I, et al. Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease. Cell Stem Cell. 23: 123-131.e6. PMID 29979986 DOI: 10.1016/j.stem.2018.06.015  0.72
2018 Kronenberg ZN, Fiddes IT, Gordon D, Murali S, Cantsilieris S, Meyerson OS, Underwood JG, Nelson BJ, Chaisson MJP, Dougherty ML, Munson KM, Hastie AR, Diekhans M, Hormozdiari F, Lorusso N, ... ... Gage FH, et al. High-resolution comparative analysis of great ape genomes. Science (New York, N.Y.). 360. PMID 29880660 DOI: 10.1126/science.aar6343  0.68
2018 Kim Y, Zheng X, Ansari Z, Bunnell MC, Herdy JR, Traxler L, Lee H, Paquola ACM, Blithikioti C, Ku M, Schlachetzki JCM, Winkler J, Edenhofer F, Glass CK, Paucar AA, ... ... Gage FH, et al. Mitochondrial Aging Defects Emerge in Directly Reprogrammed Human Neurons due to Their Metabolic Profile. Cell Reports. 23: 2550-2558. PMID 29847787 DOI: 10.1016/j.celrep.2018.04.105  0.6
2018 Stern S, Linker S, Vadodaria KC, Marchetto MC, Gage FH. Prediction of response to drug therapy in psychiatric disorders. Open Biology. 8. PMID 29794033 DOI: 10.1098/rsob.180031  0.84
2018 Strnadel J, Carromeu C, Bardy C, Navarro M, Platoshyn O, Glud AN, Marsala S, Kafka J, Miyanohara A, Kato T, Tadokoro T, Hefferan MP, Kamizato K, Yoshizumi T, Juhas S, ... ... Gage FH, et al. Survival of syngeneic and allogeneic iPSC-derived neural precursors after spinal grafting in minipigs. Science Translational Medicine. 10. PMID 29743351 DOI: 10.1126/scitranslmed.aam6651  0.68
2018 Sarkar A, Mei A, Paquola ACM, Stern S, Bardy C, Klug JR, Kim S, Neshat N, Kim HJ, Ku M, Shokhirev MN, Adamowicz DH, Marchetto MC, Jappelli R, Erwin JA, ... ... Gage FH, et al. Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro. Cell Stem Cell. 22: 684-697.e9. PMID 29727680 DOI: 10.1016/j.stem.2018.04.009  0.88
2018 Erwin JA, Paquola ACM, Singer T, Gallina I, Novotny M, Quayle C, Bedrosian TA, Alves FIA, Butcher CR, Herdy JR, Sarkar A, Lasken RS, Muotri AR, Gage FH. Author Correction: L1-associated genomic regions are deleted in somatic cells of the healthy human brain. Nature Neuroscience. PMID 29703932 DOI: 10.1038/s41593-018-0131-3  0.84
2018 Kempermann G, Gage FH, Aigner L, Song H, Curtis MA, Thuret S, Kuhn HG, Jessberger S, Frankland PW, Cameron HA, Gould E, Hen R, Abrous DN, Toni N, Schinder AF, et al. Human Adult Neurogenesis: Evidence and Remaining Questions. Cell Stem Cell. PMID 29681514 DOI: 10.1016/j.stem.2018.04.004  1
2018 Toda T, Parylak SL, Linker SB, Gage FH. The role of adult hippocampal neurogenesis in brain health and disease. Molecular Psychiatry. PMID 29679070 DOI: 10.1038/s41380-018-0036-2  0.76
2018 Mansour AA, Gonçalves JT, Bloyd CW, Li H, Fernandes S, Quang D, Johnston S, Parylak SL, Jin X, Gage FH. An in vivo model of functional and vascularized human brain organoids. Nature Biotechnology. PMID 29658944 DOI: 10.1038/nbt.4127  0.76
2018 Bedrosian TA, Quayle C, Novaresi N, Gage FH. Early life experience drives structural variation of neural genomes in mice. Science (New York, N.Y.). 359: 1395-1399. PMID 29567711 DOI: 10.1126/science.aah3378  0.4
2018 Zheng Y, Shen W, Zhang J, Yang B, Liu YN, Qi H, Yu X, Lu SY, Chen Y, Xu YZ, Li Y, Gage FH, Mi S, Yao J. Author Correction: CRISPR interference-based specific and efficient gene inactivation in the brain. Nature Neuroscience. PMID 29545585 DOI: 10.1038/s41593-018-0125-1  0.96
2018 Zheng Y, Shen W, Zhang J, Yang B, Liu YN, Qi H, Yu X, Lu SY, Chen Y, Xu YZ, Li Y, Gage FH, Mi S, Yao J. CRISPR interference-based specific and efficient gene inactivation in the brain. Nature Neuroscience. PMID 29403034 DOI: 10.1038/s41593-018-0077-5  0.96
2018 Vadodaria KC, Amatya DN, Marchetto MC, Gage FH. Modeling psychiatric disorders using patient stem cell-derived neurons: a way forward. Genome Medicine. 10: 1. PMID 29301565 DOI: 10.1186/s13073-017-0512-3  0.84
2017 Paquola ACM, Erwin JA, Gage FH. Insights into the role of somatic mosaicism in the brain. Current Opinion in Systems Biology. 1: 90-94. PMID 29226270 DOI: 10.1016/j.coisb.2016.12.004  0.56
2017 Toda T, Gage FH. Review: adult neurogenesis contributes to hippocampal plasticity. Cell and Tissue Research. PMID 29185071 DOI: 10.1007/s00441-017-2735-4  0.32
2017 Jaeger BN, Parylak SL, Gage FH. Mechanisms of dietary flavonoid action in neuronal function and neuroinflammation. Molecular Aspects of Medicine. PMID 29117513 DOI: 10.1016/j.mam.2017.11.003  0.76
2017 Erwin JA, Paquola ACM, Singer T, Gallina I, Novotny M, Quayle C, Bedrosian TA, Alves FIA, Butcher CR, Herdy JR, Sarkar A, Lasken RS, Muotri AR, Gage FH. Corrigendum: L1-associated genomic regions are deleted in somatic cells of the healthy human brain. Nature Neuroscience. 20: 1427. PMID 28949329 DOI: 10.1038/nn1017-1427a  0.84
2017 Toda T, Hsu JY, Linker SB, Hu L, Schafer ST, Mertens J, Jacinto FV, Hetzer MW, Gage FH. Nup153 Interacts with Sox2 to Enable Bimodal Gene Regulation and Maintenance of Neural Progenitor Cells. Cell Stem Cell. PMID 28919367 DOI: 10.1016/j.stem.2017.08.012  0.6
2017 Topol A, Zhu S, Hartley BJ, English J, Hauberg ME, Tran N, Rittenhouse CA, Simone A, Ruderfer DM, Johnson J, Readhead B, Hadas Y, Gochman PA, Wang YC, Shah H, ... ... Gage FH, et al. Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells. Cell Reports. 20: 2525. PMID 28877483 DOI: 10.1016/j.celrep.2017.08.073  0.44
2017 Vadodaria KC, Stern S, Marchetto MC, Gage FH. Serotonin in psychiatry: in vitro disease modeling using patient-derived neurons. Cell and Tissue Research. PMID 28812143 DOI: 10.1007/s00441-017-2670-4  0.84
2017 Linker SB, Marchetto MC, Narvaiza I, Denli AM, Gage FH. Examining non-LTR retrotransposons in the context of the evolving primate brain. Bmc Biology. 15: 68. PMID 28800766 DOI: 10.1186/s12915-017-0409-z  0.84
2017 Newkirk SJ, Lee S, Grandi FC, Gaysinskaya V, Rosser JM, Vanden Berg N, Hogarth CA, Marchetto MCN, Muotri AR, Griswold MD, Ye P, Bortvin A, Gage FH, Boeke JD, An W. Intact piRNA pathway prevents L1 mobilization in male meiosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630288 DOI: 10.1073/pnas.1701069114  0.68
2017 Santos R, Vadodaria KC, Jaeger BN, Mei A, Lefcochilos-Fogelquist S, Mendes APD, Erikson G, Shokhirev M, Randolph-Moore L, Fredlender C, Dave S, Oefner R, Fitzpatrick C, Pena M, Barron JJ, ... ... Gage FH, et al. Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells. Stem Cell Reports. 8: 1757-1769. PMID 28591655 DOI: 10.1016/j.stemcr.2017.05.011  0.84
2017 Gosselin D, Skola D, Coufal NG, Holtman IR, Schlachetzki JCM, Sajti E, Jaeger BN, O'Connor C, Fitzpatrick C, Pasillas MP, Pena M, Adair A, Gonda DG, Levy ML, Ransohoff RM, ... Gage FH, et al. An environment-dependent transcriptional network specifies human microglia identity. Science (New York, N.Y.). PMID 28546318 DOI: 10.1126/science.aal3222  0.64
2017 Franks TM, Benner C, Narvaiza I, Marchetto MCN, Young JM, Malik HS, Gage FH, Hetzer MW. Corrigendum: Evolution of a transcriptional regulator from a transmembrane nucleoporin. Genes & Development. 31: 845. PMID 28512238 DOI: 10.1101/gad.300699.117  0.6
2017 Ishii S, Torii M, Son AI, Rajendraprasad M, Morozov YM, Kawasawa YI, Salzberg AC, Fujimoto M, Brennand K, Nakai A, Mezger V, Gage FH, Rakic P, Hashimoto-Torii K. Variations in brain defects result from cellular mosaicism in the activation of heat shock signalling. Nature Communications. 8: 15157. PMID 28462912 DOI: 10.1038/ncomms15157  0.76
2017 McConnell MJ, Moran JV, Abyzov A, Akbarian S, Bae T, Cortes-Ciriano I, Erwin JA, Fasching L, Flasch DA, Freed D, Ganz J, Jaffe AE, Kwan KY, Kwon M, Lodato MA, ... ... Gage FH, et al. Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network. Science (New York, N.Y.). 356. PMID 28450582 DOI: 10.1126/science.aal1641  0.6
2017 Lacar B, Linker SB, Jaeger BN, Krishnaswami SR, Barron JJ, Kelder MJ, Parylak SL, Paquola AC, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin JA, Hsu JY, Husband D, ... ... Gage FH, et al. Corrigendum: Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nature Communications. 8: 15047. PMID 28303884 DOI: 10.1038/ncomms15047  0.76
2017 Kim Y, Santos R, Gage FH, Marchetto MC. Molecular Mechanisms of Bipolar Disorder: Progress Made and Future Challenges. Frontiers in Cellular Neuroscience. 11: 30. PMID 28261061 DOI: 10.3389/fncel.2017.00030  0.84
2017 Ramsay L, Marchetto MC, Caron M, Chen SH, Busche S, Kwan T, Pastinen T, Gage FH, Bourque G. Conserved expression of transposon-derived non-coding transcripts in primate stem cells. Bmc Genomics. 18: 214. PMID 28245871 DOI: 10.1186/s12864-017-3568-y  0.84
2016 Han J, Gage FH. A role for miR-19 in the migration of adult-born neurons and schizophrenia. Neurogenesis (Austin, Tex.). 3: e1251873. PMID 28405585 DOI: 10.1080/23262133.2016.1251873  0.64
2016 Adamowicz DH, Roy S, Salmon DP, Galasko DR, Hansen LA, Masliah E, Gage FH. Hippocampal α-Synuclein in Dementia with Lewy Bodies Contributes to Memory Impairment and is Consistent with Spread of Pathology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28039370 DOI: 10.1523/JNEUROSCI.3047-16.2016  0.4
2016 Gonçalves JT, Schafer ST, Gage FH. Adult Neurogenesis in the Hippocampus: From Stem Cells to Behavior. Cell. 167: 897-914. PMID 27814520 DOI: 10.1016/j.cell.2016.10.021  0.48
2016 Vadodaria KC, Marchetto MC, Mertens J, Gage FH. Generating human serotonergic neurons in vitro: Methodological advances. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 27716980 DOI: 10.1002/bies.201600127  0.84
2016 Erwin JA, Paquola AC, Singer T, Gallina I, Novotny M, Quayle C, Bedrosian TA, Alves FI, Butcher CR, Herdy JR, Sarkar A, Lasken RS, Muotri AR, Gage FH. L1-associated genomic regions are deleted in somatic cells of the healthy human brain. Nature Neuroscience. PMID 27618310 DOI: 10.1038/nn.4388  0.84
2016 Du H, Deng W, Aimone JB, Ge M, Parylak S, Walch K, Zhang W, Cook J, Song H, Wang L, Gage FH, Mu Y. Dopaminergic inputs in the dentate gyrus direct the choice of memory encoding. Proceedings of the National Academy of Sciences of the United States of America. PMID 27573822 DOI: 10.1073/pnas.1606951113  1
2016 Chailangkarn T, Trujillo CA, Freitas BC, Hrvoj-Mihic B, Herai RH, Yu DX, Brown TT, Marchetto MC, Bardy C, McHenry L, Stefanacci L, Järvinen A, Searcy YM, DeWitt M, Wong W, ... ... Gage FH, et al. A human neurodevelopmental model for Williams syndrome. Nature. PMID 27509850 DOI: 10.1038/nature19067  0.84
2016 Nuttle X, Giannuzzi G, Duyzend MH, Schraiber JG, Narvaiza I, Sudmant PH, Penn O, Chiatante G, Malig M, Huddleston J, Benner C, Camponeschi F, Ciofi-Baffoni S, Stessman HA, Marchetto MC, ... ... Gage FH, et al. Emergence of a Homo sapiens-specific gene family and chromosome 16p11.2 CNV susceptibility. Nature. PMID 27487209 DOI: 10.1038/nature19075  0.6
2016 den Hurk MV, Kenis G, Bardy C, van den Hove DL, Gage FH, Steinbusch HW, Rutten BP. Transcriptional and epigenetic mechanisms of cellular reprogramming to induced pluripotency. Epigenomics. PMID 27419933 DOI: 10.2217/epi-2016-0032  0.4
2016 Padmanabhan K, Osakada F, Tarabrina A, Kizer E, Callaway EM, Gage FH, Sejnowski TJ. Diverse Representations of Olfactory Information in Centrifugal Feedback Projections. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7535-45. PMID 27413162 DOI: 10.1523/JNEUROSCI.3358-15.2016  0.88
2016 Han J, Kim HJ, Schafer ST, Paquola A, Clemenson GD, Toda T, Oh J, Pankonin AR, Lee BS, Johnston ST, Sarkar A, Denli AM, Gage FH. Functional Implications of miR-19 in the Migration of Newborn Neurons in the Adult Brain. Neuron. 91: 79-89. PMID 27387650 DOI: 10.1016/j.neuron.2016.05.034  1
2016 Marchetto MC, Belinson H, Tian Y, Freitas BC, Fu C, Vadodaria KC, Beltrao-Braga PC, Trujillo CA, Mendes AP, Padmanabhan K, Nunez Y, Ou J, Ghosh H, Wright R, Brennand KJ, ... ... Gage FH, et al. Altered proliferation and networks in neural cells derived from idiopathic autistic individuals. Molecular Psychiatry. PMID 27378147 DOI: 10.1038/mp.2016.95  0.88
2016 Lacar B, Linker SB, Jaeger BN, Krishnaswami SR, Barron JJ, Kelder MJ, Parylak SL, Paquola AC, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin JA, Hsu JY, Husband D, ... ... Gage FH, et al. Corrigendum: Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nature Communications. 7: 12020. PMID 27295945 DOI: 10.1038/ncomms12020  0.76
2016 Zheng X, Boyer L, Jin M, Mertens J, Kim Y, Ma L, Ma L, Hamm M, Gage FH, Hunter T. Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation. Elife. 5. PMID 27282387 DOI: 10.7554/eLife.13374  1
2016 Bedrosian TA, Linker S, Gage FH. Environment-driven somatic mosaicism in brain disorders. Genome Medicine. 8: 58. PMID 27215330 DOI: 10.1186/s13073-016-0317-9  1
2016 Franks TM, Benner C, Narvaiza I, Marchetto MC, Young JM, Malik HS, Gage FH, Hetzer MW. Evolution of a transcriptional regulator from a transmembrane nucleoporin. Genes & Development. PMID 27198230 DOI: 10.1101/gad.280941.116  0.84
2016 Poo MM, Pignatelli M, Ryan TJ, Tonegawa S, Bonhoeffer T, Martin KC, Rudenko A, Tsai LH, Tsien RW, Fishell G, Mullins C, Gonçalves JT, Shtrahman M, Johnston ST, Gage FH, et al. What is memory? The present state of the engram. Bmc Biology. 14: 40. PMID 27197636 DOI: 10.1186/s12915-016-0261-6  0.6
2016 Mertens J, Marchetto MC, Bardy C, Gage FH. Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience. Nature Reviews. Neuroscience. PMID 27194476 DOI: 10.1038/nrn.2016.46  0.84
2016 Oedegaard KJ, Alda M, Anand A, Andreassen OA, Balaraman Y, Berrettini WH, Bhattacharjee A, Brennand KJ, Burdick KE, Calabrese JR, Calkin CV, Claasen A, Coryell WH, Craig D, DeModena A, ... ... Gage FH, et al. The Pharmacogenomics of Bipolar Disorder study (PGBD): identification of genes for lithium response in a prospective sample. Bmc Psychiatry. 16: 129. PMID 27150464 DOI: 10.1186/s12888-016-0732-x  0.92
2016 Gonçalves JT, Bloyd CW, Shtrahman M, Johnston ST, Schafer ST, Parylak SL, Tran T, Chang T, Gage FH. In vivo imaging of dendritic pruning in dentate granule cells. Nature Neuroscience. PMID 27135217 DOI: 10.1038/nn.4301  0.48
2016 Topol A, Zhu S, Hartley BJ, English J, Hauberg ME, Tran N, Rittenhouse CA, Simone A, Ruderfer DM, Johnson J, Readhead B, Hadas Y, Gochman PA, Wang YC, Shah H, ... ... Gage FH, et al. Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells. Cell Reports. PMID 27117414 DOI: 10.1016/j.celrep.2016.03.090  0.48
2016 Lacar B, Linker SB, Jaeger BN, Krishnaswami S, Barron J, Kelder M, Parylak S, Paquola A, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin J, Hsu JY, Husband D, ... ... Gage FH, et al. Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nature Communications. 7: 11022. PMID 27090946 DOI: 10.1038/ncomms11022  0.76
2016 Harrison BJ, Venkat G, Lamb JL, Hutson TH, Drury C, Rau KK, Bunge MB, Mendell LM, Gage FH, Johnson RD, Hill CE, Rouchka EC, Moon LD, Petruska JC. The Adaptor Protein CD2AP Is a Coordinator of Neurotrophin Signaling-Mediated Axon Arbor Plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 4259-75. PMID 27076424 DOI: 10.1523/JNEUROSCI.2423-15.2016  0.48
2016 Ettle B, Kerman BE, Valera E, Gillmann C, Schlachetzki JC, Reiprich S, Büttner C, Ekici AB, Reis A, Wegner M, Bäuerle T, Riemenschneider MJ, Masliah E, Gage FH, Winkler J. α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy. Acta Neuropathologica. PMID 27059609 DOI: 10.1007/s00401-016-1572-y  0.6
2016 Otani T, Marchetto MC, Gage FH, Simons BD, Livesey FJ. 2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size. Cell Stem Cell. 18: 467-80. PMID 27049876 DOI: 10.1016/j.stem.2016.03.003  0.84
2016 Zheng X, Boyer L, Jin M, Kim Y, Fan W, Bardy C, Berggren T, Evans RM, Gage FH, Hunter T. Alleviation of neuronal energy deficiency by mTOR inhibition as a treatment for mitochondria-related neurodegeneration. Elife. 5. PMID 27008180 DOI: 10.7554/eLife.13378  1
2016 Mishra HK, Prots I, Havlicek S, Kohl Z, Perez-Branguli F, Boerstler T, Anneser L, Minakaki G, Wend H, Hampl M, Leone M, Brückner M, Klucken J, Reis A, Boyer L, ... ... Gage FH, et al. GSK3ß-dependent dysregulation of neurodevelopment in SPG11-patient iPSC model. Annals of Neurology. PMID 26971897 DOI: 10.1002/ana.24633  0.6
2016 Krishnaswami SR, Grindberg RV, Novotny M, Venepally P, Lacar B, Bhutani K, Linker SB, Pham S, Erwin JA, Miller JA, Hodge R, McCarthy JK, Kelder M, McCorrison J, Aevermann BD, ... ... Gage FH, et al. Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons. Nature Protocols. 11: 499-524. PMID 26890679 DOI: 10.1038/nprot.2016.015  0.88
2016 Weissman IL, Gage FH. A Mechanism for Somatic Brain Mosaicism. Cell. 164: 593-5. PMID 26871622 DOI: 10.1016/j.cell.2016.01.048  1
2016 Tang X, Kim J, Zhou L, Wengert E, Zhang L, Wu Z, Carromeu C, Muotri AR, Marchetto MC, Gage FH, Chen G. KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome. Proceedings of the National Academy of Sciences of the United States of America. PMID 26733678 DOI: 10.1073/pnas.1524013113  1
2015 Sarkar A, Marchetto MC, Gage FH. Synaptic activity: an emerging player in schizophrenia. Brain Research. PMID 26723567 DOI: 10.1016/j.brainres.2015.12.028  1
2015 Harrison BJ, Venkat G, Hutson T, Rau KK, Bunge MB, Mendell LM, Gage FH, Johnson RD, Hill C, Rouchka EC, Moon L, Petruska JC. Transcriptional changes in sensory ganglia associated with primary afferent axon collateral sprouting in spared dermatome model. Genomics Data. 6: 249-52. PMID 26697387 DOI: 10.1016/j.gdata.2015.10.005  0.48
2015 Duricki DA, Hutson TH, Kathe C, Soleman S, Gonzalez-Carter D, Petruska JC, Shine HD, Chen Q, Wood TC, Bernanos M, Cash D, Williams SC, Gage FH, Moon LD. Delayed intramuscular human neurotrophin-3 improves recovery in adult and elderly rats after stroke. Brain : a Journal of Neurology. PMID 26614754 DOI: 10.1093/brain/awv341  0.48
2015 Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, ... ... Gage FH, et al. Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem Cell Reports. PMID 26610635 DOI: 10.1016/j.stemcr.2015.10.011  1
2015 Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames T, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, ... ... Gage FH, et al. Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder. Nature. PMID 26605530 DOI: 10.1038/nature16182  0.92
2015 Johnston ST, Shtrahman M, Parylak S, Gonçalves JT, Gage FH. Paradox of Pattern Separation and Adult Neurogenesis: A Dual Role for New Neurons Balancing Memory Resolution and Robustness. Neurobiology of Learning and Memory. PMID 26549627 DOI: 10.1016/j.nlm.2015.10.013  1
2015 Kim HJ, Denli AM, Wright R, Baul TD, Clemenson GD, Morcos AS, Zhao C, Schafer ST, Gage FH, Kagalwala MN. REST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 14872-84. PMID 26538656 DOI: 10.1523/JNEUROSCI.4286-14.2015  1
2015 Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames T, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, ... ... Gage FH, et al. Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder. Nature. PMID 26524527 DOI: 10.1038/nature15526  0.48
2015 Denli AM, Narvaiza I, Kerman BE, Pena M, Benner C, Marchetto MC, Diedrich JK, Aslanian A, Ma J, Moresco JJ, Moore L, Hunter T, Saghatelian A, Gage FH. Primate-Specific ORF0 Contributes to Retrotransposon-Mediated Diversity. Cell. 163: 583-93. PMID 26496605 DOI: 10.1016/j.cell.2015.09.025  0.48
2015 Mu Y, Zhao C, Toni N, Yao J, Gage FH. Distinct roles of NMDA receptors at different stages of granule cell development in the adult brain. Elife. 4. PMID 26473971 DOI: 10.7554/eLife.07871  1
2015 Mertens J, Paquola AC, Ku M, Hatch E, Böhnke L, Ladjevardi S, McGrath S, Campbell B, Lee H, Herdy JR, Gonçalves JT, Toda T, Kim Y, Winkler J, Yao J, ... ... Gage FH, et al. Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects. Cell Stem Cell. PMID 26456686 DOI: 10.1016/j.stem.2015.09.001  1
2015 Tashiro A, Zhao C, Suh H, Gage FH. Preparation and Use of Retroviral Vectors for Labeling, Imaging, and Genetically Manipulating Cells. Cold Spring Harbor Protocols. 2015: pdb.top086363. PMID 26430260 DOI: 10.1101/pdb.top086363  1
2015 Tashiro A, Zhao C, Suh H, Gage FH. Analysis of Spine Motility of Newborn Granule Cells in Acute Brain Slices. Cold Spring Harbor Protocols. 2015: pdb.prot086397. PMID 26430257 DOI: 10.1101/pdb.prot086397  1
2015 Tashiro A, Zhao C, Suh H, Gage FH. Imaging Newborn Granule Cells in Fixed Sections. Cold Spring Harbor Protocols. 2015: pdb.prot086389. PMID 26430256 DOI: 10.1101/pdb.prot086389  1
2015 Tashiro A, Zhao C, Suh H, Gage FH. Purification and Injection of Retroviral Vectors. Cold Spring Harbor Protocols. 2015: pdb.prot086371. PMID 26430255 DOI: 10.1101/pdb.prot086371  1
2015 Prescott SL, Srinivasan R, Marchetto MC, Grishina I, Narvaiza I, Selleri L, Gage FH, Swigut T, Wysocka J. Enhancer Divergence and cis-Regulatory Evolution in the Human and Chimp Neural Crest. Cell. 163: 68-83. PMID 26365491 DOI: 10.1016/j.cell.2015.08.036  0.48
2015 Kempermann G, Song H, Gage FH. Neurogenesis in the Adult Hippocampus. Cold Spring Harbor Perspectives in Biology. 7. PMID 26330519 DOI: 10.1101/cshperspect.a018812  1
2015 Jovičić A, Mertens J, Boeynaems S, Bogaert E, Chai N, Yamada SB, Paul JW, Sun S, Herdy JR, Bieri G, Kramer NJ, Gage FH, Van Den Bosch L, Robberecht W, Gitler AD. Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS. Nature Neuroscience. 18: 1226-9. PMID 26308983 DOI: 10.1038/nn.4085  0.36
2015 Firth AL, Menon T, Parker GS, Qualls SJ, Lewis BM, Ke E, Dargitz CT, Wright R, Khanna A, Gage FH, Verma IM. Functional Gene Correction for Cystic Fibrosis in Lung Epithelial Cells Generated from Patient iPSCs. Cell Reports. 12: 1385-90. PMID 26299960 DOI: 10.1016/j.celrep.2015.07.062  0.56
2015 Zhao C, Jou J, Wolff LJ, Sun H, Gage FH. Spine morphogenesis in newborn granule cells is differentially regulated in the outer and middle molecular layers. The Journal of Comparative Neurology. 523: 1588. PMID 26109421 DOI: 10.1002/cne.23800  1
2015 Han J, Sarkar A, Gage FH. MIR137: big impacts from small changes. Nature Neuroscience. 18: 931-3. PMID 26108719 DOI: 10.1038/nn.4045  0.84
2015 Kerman BE, Kim HJ, Padmanabhan K, Mei A, Georges S, Joens MS, Fitzpatrick JA, Jappelli R, Chandross KJ, August P, Gage FH. In vitro myelin formation using embryonic stem cells. Development (Cambridge, England). 142: 2213-25. PMID 26015546 DOI: 10.1242/dev.116517  1
2015 Bardy C, van den Hurk M, Eames T, Marchand C, Hernandez RV, Kellogg M, Gorris M, Galet B, Palomares V, Brown J, Bang AG, Mertens J, Böhnke L, Boyer L, Simon S, ... Gage FH, et al. Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro. Proceedings of the National Academy of Sciences of the United States of America. 112: E2725-34. PMID 25870293 DOI: 10.1073/pnas.1504393112  1
2015 Pei L, Mu Y, Leblanc M, Alaynick W, Barish GD, Pankratz M, Tseng TW, Kaufman S, Liddle C, Yu RT, Downes M, Pfaff SL, Auwerx J, Gage FH, Evans RM. Dependence of hippocampal function on ERRγ-regulated mitochondrial metabolism. Cell Metabolism. 21: 628-36. PMID 25863252 DOI: 10.1016/j.cmet.2015.03.004  1
2015 Adamowicz DH, Mertens J, Gage FH. Alzheimer's disease: distinct stages in neurogenic decline? Biological Psychiatry. 77: 680-2. PMID 25835286 DOI: 10.1016/j.biopsych.2015.02.021  1
2015 Amador-Arjona A, Cimadamore F, Huang CT, Wright R, Lewis S, Gage FH, Terskikh AV. SOX2 primes the epigenetic landscape in neural precursors enabling proper gene activation during hippocampal neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. 112: E1936-45. PMID 25825708 DOI: 10.1073/pnas.1421480112  1
2015 Schafer ST, Han J, Pena M, von Bohlen Und Halbach O, Peters J, Gage FH. The Wnt adaptor protein ATP6AP2 regulates multiple stages of adult hippocampal neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 4983-98. PMID 25810528 DOI: 10.1523/JNEUROSCI.4130-14.2015  1
2015 Deng W, Gage FH. The effect of immature adult-born dentate granule cells on hyponeophagial behavior is related to their roles in learning and memory. Frontiers in Systems Neuroscience. 9: 34. PMID 25798094 DOI: 10.3389/fnsys.2015.00034  1
2015 Clemenson GD, Lee SW, Deng W, Barrera VR, Iwamoto KS, Fanselow MS, Gage FH. Enrichment rescues contextual discrimination deficit associated with immediate shock. Hippocampus. 25: 385-92. PMID 25330953 DOI: 10.1002/hipo.22380  1
2015 Krzisch M, Temprana SG, Mongiat LA, Armida J, Schmutz V, Virtanen MA, Kocher-Braissant J, Kraftsik R, Vutskits L, Conzelmann KK, Bergami M, Gage FH, Schinder AF, Toni N. Pre-existing astrocytes form functional perisynaptic processes on neurons generated in the adult hippocampus. Brain Structure & Function. 220: 2027-42. PMID 24748560 DOI: 10.1007/s00429-014-0768-y  1
2014 Pankevich DE, Altevogt BM, Dunlop J, Gage FH, Hyman SE. Improving and accelerating drug development for nervous system disorders. Neuron. 84: 546-53. PMID 25442933 DOI: 10.1016/j.neuron.2014.10.007  1
2014 Hook V, Brennand KJ, Kim Y, Toneff T, Funkelstein L, Lee KC, Ziegler M, Gage FH. Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons. Stem Cell Reports. 3: 531-8. PMID 25358781 DOI: 10.1016/j.stemcr.2014.08.001  1
2014 Aimone JB, Li Y, Lee SW, Clemenson GD, Deng W, Gage FH. Regulation and function of adult neurogenesis: from genes to cognition. Physiological Reviews. 94: 991-1026. PMID 25287858 DOI: 10.1152/physrev.00004.2014  1
2014 Jessberger S, Gage FH. Adult neurogenesis: bridging the gap between mice and humans. Trends in Cell Biology. 24: 558-63. PMID 25124338 DOI: 10.1016/j.tcb.2014.07.003  1
2014 Marchetto MC, Gage FH. Your brain under the microscope: the promise of stem cells. Cerebrum : the Dana Forum On Brain Science. 2014: 1. PMID 25009691  0.84
2014 Erwin JA, Marchetto MC, Gage FH. Mobile DNA elements in the generation of diversity and complexity in the brain. Nature Reviews. Neuroscience. 15: 497-506. PMID 25005482 DOI: 10.1038/nrn3730  1
2014 Stein JL, de la Torre-Ubieta L, Tian Y, Parikshak NN, Hernández IA, Marchetto MC, Baker DK, Lu D, Hinman CR, Lowe JK, Wexler EM, Muotri AR, Gage FH, Kosik KS, Geschwind DH. A quantitative framework to evaluate modeling of cortical development by neural stem cells. Neuron. 83: 69-86. PMID 24991955 DOI: 10.1016/j.neuron.2014.05.035  1
2014 Yu DX, Marchetto MC, Gage FH. How to make a hippocampal dentate gyrus granule neuron. Development (Cambridge, England). 141: 2366-75. PMID 24917496 DOI: 10.1242/dev.096776  1
2014 Bekinschtein P, Kent BA, Oomen CA, Clemenson GD, Gage FH, Saksida LM, Bussey TJ. Brain-derived neurotrophic factor interacts with adult-born immature cells in the dentate gyrus during consolidation of overlapping memories. Hippocampus. 24: 905-11. PMID 24825389 DOI: 10.1002/hipo.22304  1
2014 Winner B, Marchetto MC, Winkler J, Gage FH. Human-induced pluripotent stem cells pave the road for a better understanding of motor neuron disease. Human Molecular Genetics. 23: R27-34. PMID 24821704 DOI: 10.1093/hmg/ddu205  1
2014 Hashimoto-Torii K, Torii M, Fujimoto M, Nakai A, El Fatimy R, Mezger V, Ju MJ, Ishii S, Chao SH, Brennand KJ, Gage FH, Rakic P. Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders. Neuron. 82: 560-72. PMID 24726381 DOI: 10.1016/j.neuron.2014.03.002  1
2014 Firth AL, Dargitz CT, Qualls SJ, Menon T, Wright R, Singer O, Gage FH, Khanna A, Verma IM. Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 111: E1723-30. PMID 24706852 DOI: 10.1073/pnas.1403470111  1
2014 Yu DX, Di Giorgio FP, Yao J, Marchetto MC, Brennand K, Wright R, Mei A, McHenry L, Lisuk D, Grasmick JM, Silberman P, Silberman G, Jappelli R, Gage FH. Modeling hippocampal neurogenesis using human pluripotent stem cells. Stem Cell Reports. 2: 295-310. PMID 24672753 DOI: 10.1016/j.stemcr.2014.01.009  1
2014 Rockenstein E, Nuber S, Overk CR, Ubhi K, Mante M, Patrick C, Adame A, Trejo-Morales M, Gerez J, Picotti P, Jensen PH, Campioni S, Riek R, Winkler J, Gage FH, et al. Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo. Brain : a Journal of Neurology. 137: 1496-513. PMID 24662516 DOI: 10.1093/brain/awu057  1
2014 Pao GM, Zhu Q, Perez-Garcia CG, Chou SJ, Suh H, Gage FH, O'Leary DD, Verma IM. Role of BRCA1 in brain development. Proceedings of the National Academy of Sciences of the United States of America. 111: E1240-8. PMID 24639535 DOI: 10.1073/pnas.1400783111  1
2014 Zhao C, Jou J, Wolff LJ, Sun H, Gage FH. Spine morphogenesis in newborn granule cells is differentially regulated in the outer and middle molecular layers. The Journal of Comparative Neurology. 522: 2756-66. PMID 24610721 DOI: 10.1002/cne.23581  1
2014 Lacar B, Parylak SL, Vadodaria KC, Sarkar A, Gage FH. Increasing the resolution of the adult neurogenesis picture. F1000prime Reports. 6: 8. PMID 24592320 DOI: 10.12703/P6-8  1
2014 Crotti A, Benner C, Kerman BE, Gosselin D, Lagier-Tourenne C, Zuccato C, Cattaneo E, Gage FH, Cleveland DW, Glass CK. Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors. Nature Neuroscience. 17: 513-21. PMID 24584051 DOI: 10.1038/nn.3668  1
2014 Vadodaria KC, Gage FH. SnapShot: adult hippocampal neurogenesis. Cell. 156: 1114-1114.e1. PMID 24581504 DOI: 10.1016/j.cell.2014.02.029  1
2014 Wright R, Réthelyi JM, Gage FH. Enhancing induced pluripotent stem cell models of schizophrenia. Jama Psychiatry. 71: 334-5. PMID 24382673 DOI: 10.1001/jamapsychiatry.2013.4239  1
2014 Havlicek S, Kohl Z, Mishra HK, Prots I, Eberhardt E, Denguir N, Wend H, Plötz S, Boyer L, Marchetto MC, Aigner S, Sticht H, Groemer TW, Hehr U, Lampert A, ... ... Gage FH, et al. Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons. Human Molecular Genetics. 23: 2527-41. PMID 24381312 DOI: 10.1093/hmg/ddt644  1
2014 Parylak SL, Deng W, Gage FH. Mother's milk programs offspring's cognition. Nature Neuroscience. 17: 8-9. PMID 24369371 DOI: 10.1038/nn.3611  1
2014 Hrvoj-Mihic B, Marchetto MC, Gage FH, Semendeferi K, Muotri AR. Novel tools, classic techniques: evolutionary studies using primate pluripotent stem cells. Biological Psychiatry. 75: 929-35. PMID 24041506 DOI: 10.1016/j.biopsych.2013.08.007  1
2013 Grindberg RV, Yee-Greenbaum JL, McConnell MJ, Novotny M, O'Shaughnessy AL, Lambert GM, Araúzo-Bravo MJ, Lee J, Fishman M, Robbins GE, Lin X, Venepally P, Badger JH, Galbraith DW, Gage FH, et al. RNA-sequencing from single nuclei. Proceedings of the National Academy of Sciences of the United States of America. 110: 19802-7. PMID 24248345 DOI: 10.1073/pnas.1319700110  1
2013 Bekinschtein P, Kent BA, Oomen CA, Clemenson GD, Gage FH, Saksida LM, Bussey TJ. BDNF in the dentate gyrus is required for consolidation of "pattern-separated" memories. Cell Reports. 5: 759-68. PMID 24209752 DOI: 10.1016/j.celrep.2013.09.027  1
2013 Reilly MT, Faulkner GJ, Dubnau J, Ponomarev I, Gage FH. The role of transposable elements in health and diseases of the central nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17577-86. PMID 24198348 DOI: 10.1523/JNEUROSCI.3369-13.2013  1
2013 Gage FH, Temple S. Neural stem cells: generating and regenerating the brain. Neuron. 80: 588-601. PMID 24183012 DOI: 10.1016/j.neuron.2013.10.037  1
2013 McConnell MJ, Lindberg MR, Brennand KJ, Piper JC, Voet T, Cowing-Zitron C, Shumilina S, Lasken RS, Vermeesch JR, Hall IM, Gage FH. Mosaic copy number variation in human neurons. Science (New York, N.Y.). 342: 632-7. PMID 24179226 DOI: 10.1126/science.1243472  1
2013 Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, Å estan N, ... Gage FH, et al. Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development (Cambridge, England). 140: 4633-44. PMID 24154525 DOI: 10.1242/dev.097212  1
2013 Marchetto MC, Narvaiza I, Denli AM, Benner C, Lazzarini TA, Nathanson JL, Paquola AC, Desai KN, Herai RH, Weitzman MD, Yeo GW, Muotri AR, Gage FH. Differential L1 regulation in pluripotent stem cells of humans and apes. Nature. 503: 525-9. PMID 24153179 DOI: 10.1038/nature12686  1
2013 Deshmukh VA, Tardif V, Lyssiotis CA, Green CC, Kerman B, Kim HJ, Padmanabhan K, Swoboda JG, Ahmad I, Kondo T, Gage FH, Theofilopoulos AN, Lawson BR, Schultz PG, Lairson LL. A regenerative approach to the treatment of multiple sclerosis. Nature. 502: 327-32. PMID 24107995 DOI: 10.1038/nature12647  1
2013 Sung TC, Chen Z, Thuret S, Vilar M, Gage FH, Riek R, Lee KF. P45 forms a complex with FADD and promotes neuronal cell survival following spinal cord injury. Plos One. 8: e69286. PMID 23935974 DOI: 10.1371/journal.pone.0069286  1
2013 Tang X, Zhou L, Wagner AM, Marchetto MC, Muotri AR, Gage FH, Chen G. Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells. Stem Cell Research. 11: 743-57. PMID 23759711 DOI: 10.1016/j.scr.2013.05.002  1
2013 Yu DX, Marchetto MC, Gage FH. Therapeutic translation of iPSCs for treating neurological disease. Cell Stem Cell. 12: 678-88. PMID 23746977 DOI: 10.1016/j.stem.2013.05.018  1
2013 Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, ... ... Gage FH, et al. Response to comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells". Science Translational Medicine. 5: 188lr2. PMID 23740898 DOI: 10.1126/scitranslmed.3005697  1
2013 Rangel LM, Quinn LK, Chiba AA, Gage FH, Aimone JB. A hypothesis for temporal coding of young and mature granule cells. Frontiers in Neuroscience. 7: 75. PMID 23717259 DOI: 10.3389/fnins.2013.00075  1
2013 Li Y, Stam FJ, Aimone JB, Goulding M, Callaway EM, Gage FH. Molecular layer perforant path-associated cells contribute to feed-forward inhibition in the adult dentate gyrus. Proceedings of the National Academy of Sciences of the United States of America. 110: 9106-11. PMID 23671081 DOI: 10.1073/pnas.1306912110  1
2013 Herzog CD, Brown L, Kruegel BR, Wilson A, Tansey MG, Gage FH, Johnson EM, Bartus RT. Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120). Neurobiology of Disease. 58: 38-48. PMID 23631873 DOI: 10.1016/j.nbd.2013.04.011  1
2013 Vilchez D, Boyer L, Lutz M, Merkwirth C, Morantte I, Tse C, Spencer B, Page L, Masliah E, Berggren WT, Gage FH, Dillin A. FOXO4 is necessary for neural differentiation of human embryonic stem cells. Aging Cell. 12: 518-22. PMID 23551888 DOI: 10.1111/acel.12067  1
2013 Deng W, Mayford M, Gage FH. Selection of distinct populations of dentate granule cells in response to inputs as a mechanism for pattern separation in mice. Elife. 2: e00312. PMID 23538967 DOI: 10.7554/eLife.00312  1
2013 Wang X, Zhao Y, Zhang X, Badie H, Zhou Y, Mu Y, Loo LS, Cai L, Thompson RC, Yang B, Chen Y, Johnson PF, Wu C, Bu G, Mobley WC, ... ... Gage FH, et al. Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome. Nature Medicine. 19: 473-80. PMID 23524343 DOI: 10.1038/nm.3117  1
2013 Liang Y, Franks TM, Marchetto MC, Gage FH, Hetzer MW. Dynamic association of NUP98 with the human genome. Plos Genetics. 9: e1003308. PMID 23468646 DOI: 10.1371/journal.pgen.1003308  1
2013 Shimozaki K, Clemenson GD, Gage FH. Paired related homeobox protein 1 is a regulator of stemness in adult neural stem/progenitor cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4066-75. PMID 23447615 DOI: 10.1523/JNEUROSCI.4586-12.2013  1
2013 Kurian L, Sancho-Martinez I, Nivet E, Aguirre A, Moon K, Pendaries C, Volle-Challier C, Bono F, Herbert JM, Pulecio J, Xia Y, Li M, Montserrat N, Ruiz S, Dubova I, ... ... Gage FH, et al. Conversion of human fibroblasts to angioblast-like progenitor cells. Nature Methods. 10: 77-83. PMID 23202434 DOI: 10.1038/nmeth.2255  1
2012 Gage FH. Transplantation in the future. Progress in Brain Research. 200: 7-13. PMID 23195412 DOI: 10.1016/B978-0-444-59575-1.00001-6  1
2012 Gage FH. Transplantation in the future. Progress in Brain Research. 201: 7-13. PMID 23186707 DOI: 10.1016/B978-0-444-59544-7.00001-9  1
2012 Winner B, Regensburger M, Schreglmann S, Boyer L, Prots I, Rockenstein E, Mante M, Zhao C, Winkler J, Masliah E, Gage FH. Role of α-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16906-16. PMID 23175842 DOI: 10.1523/JNEUROSCI.2723-12.2012  1
2012 Bellin M, Marchetto MC, Gage FH, Mummery CL. Induced pluripotent stem cells: the new patient? Nature Reviews. Molecular Cell Biology. 13: 713-26. PMID 23034453 DOI: 10.1038/nrm3448  1
2012 Vivar C, Potter MC, Choi J, Lee JY, Stringer TP, Callaway EM, Gage FH, Suh H, van Praag H. Monosynaptic inputs to new neurons in the dentate gyrus. Nature Communications. 3: 1107. PMID 23033083 DOI: 10.1038/ncomms2101  1
2012 Vilchez D, Boyer L, Morantte I, Lutz M, Merkwirth C, Joyce D, Spencer B, Page L, Masliah E, Berggren WT, Gage FH, Dillin A. Increased proteasome activity in human embryonic stem cells is regulated by PSMD11. Nature. 489: 304-8. PMID 22972301 DOI: 10.1038/nature11468  1
2012 Boyer LF, Campbell B, Larkin S, Mu Y, Gage FH. Dopaminergic differentiation of human pluripotent cells. Current Protocols in Stem Cell Biology. Unit1H.6. PMID 22872424 DOI: 10.1002/9780470151808.sc01h06s22  1
2012 Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, ... ... Gage FH, et al. Drug screening for ALS using patient-specific induced pluripotent stem cells. Science Translational Medicine. 4: 145ra104. PMID 22855461 DOI: 10.1126/scitranslmed.3004052  1
2012 Giorgetti A, Marchetto MC, Li M, Yu D, Fazzina R, Mu Y, Adamo A, Paramonov I, Cardoso JC, Monasterio MB, Bardy C, Cassiani-Ingoni R, Liu GH, Gage FH, Izpisua Belmonte JC. Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc. Proceedings of the National Academy of Sciences of the United States of America. 109: 12556-61. PMID 22814375 DOI: 10.1073/pnas.1209523109  1
2012 Marchetto MC, Gage FH. Modeling brain disease in a dish: really? Cell Stem Cell. 10: 642-5. PMID 22704498 DOI: 10.1016/j.stem.2012.05.008  1
2012 Yao J, Mu Y, Gage FH. Neural stem cells: mechanisms and modeling. Protein & Cell. 3: 251-61. PMID 22549585 DOI: 10.1007/s13238-012-2033-6  1
2012 Ge WP, Miyawaki A, Gage FH, Jan YN, Jan LY. Local generation of glia is a major astrocyte source in postnatal cortex. Nature. 484: 376-80. PMID 22456708 DOI: 10.1038/nature10959  1
2012 Bracko O, Singer T, Aigner S, Knobloch M, Winner B, Ray J, Clemenson GD, Suh H, Couillard-Despres S, Aigner L, Gage FH, Jessberger S. Gene expression profiling of neural stem cells and their neuronal progeny reveals IGF2 as a regulator of adult hippocampal neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3376-87. PMID 22399759 DOI: 10.1523/JNEUROSCI.4248-11.2012  1
2012 Gage FH, Muotri AR. What makes each brain unique. Scientific American. 306: 26-31. PMID 22375319 DOI: 10.1038/scientificamerican0312-20  1
2012 Li Y, Aimone JB, Xu X, Callaway EM, Gage FH. Development of GABAergic inputs controls the contribution of maturing neurons to the adult hippocampal network. Proceedings of the National Academy of Sciences of the United States of America. 109: 4290-5. PMID 22371596 DOI: 10.1073/pnas.1120754109  1
2012 Thuret S, Thallmair M, Horky LL, Gage FH. Enhanced functional recovery in MRL/MpJ mice after spinal cord dorsal hemisection. Plos One. 7: e30904. PMID 22348029 DOI: 10.1371/journal.pone.0030904  1
2012 Israel MA, Yuan SH, Bardy C, Reyna SM, Mu Y, Herrera C, Hefferan MP, Van Gorp S, Nazor KL, Boscolo FS, Carson CT, Laurent LC, Marsala M, Gage FH, Remes AM, et al. Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. Nature. 482: 216-20. PMID 22278060 DOI: 10.1038/nature10821  1
2012 Gage FH. ISSCR: beginning the next chapter. Cell Stem Cell. 10: 29-31. PMID 22226353 DOI: 10.1016/j.stem.2011.12.009  1
2012 Han J, Denli AM, Gage FH. The enemy within: intronic miR-26b represses its host gene, ctdsp2, to regulate neurogenesis. Genes & Development. 26: 6-10. PMID 22215805 DOI: 10.1101/gad.184416.111  1
2012 Boyce VS, Park J, Gage FH, Mendell LM. Differential effects of brain-derived neurotrophic factor and neurotrophin-3 on hindlimb function in paraplegic rats. The European Journal of Neuroscience. 35: 221-32. PMID 22211901 DOI: 10.1111/j.1460-9568.2011.07950.x  1
2012 Shimozaki K, Zhang CL, Suh H, Denli AM, Evans RM, Gage FH. SRY-box-containing gene 2 regulation of nuclear receptor tailless (Tlx) transcription in adult neural stem cells. The Journal of Biological Chemistry. 287: 5969-78. PMID 22194602 DOI: 10.1074/jbc.M111.290403  1
2012 Lee SW, Clemenson GD, Gage FH. New neurons in an aged brain. Behavioural Brain Research. 227: 497-507. PMID 22024433 DOI: 10.1016/j.bbr.2011.10.009  1
2012 Zhao C, Warner-Schmidt J, Duman RS, Gage FH. Electroconvulsive seizure promotes spine maturation in newborn dentate granule cells in adult rat. Developmental Neurobiology. 72: 937-42. PMID 21976455 DOI: 10.1002/dneu.20986  1
2012 Brennand KJ, Gage FH. Modeling psychiatric disorders through reprogramming. Disease Models & Mechanisms. 5: 26-32. PMID 21954066 DOI: 10.1242/dmm.008268  1
2011 Mu Y, Gage FH. Adult hippocampal neurogenesis and its role in Alzheimer's disease. Molecular Neurodegeneration. 6: 85. PMID 22192775 DOI: 10.1186/1750-1326-6-85  1
2011 Coufal NG, Garcia-Perez JL, Peng GE, Marchetto MC, Muotri AR, Mu Y, Carson CT, Macia A, Moran JV, Gage FH. Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 20382-7. PMID 22159035 DOI: 10.1073/pnas.1100273108  1
2011 Brennand KJ, Gage FH. Concise review: the promise of human induced pluripotent stem cell-based studies of schizophrenia. Stem Cells (Dayton, Ohio). 29: 1915-22. PMID 22009633 DOI: 10.1002/stem.762  1
2011 Kuwabara T, Kagalwala MN, Onuma Y, Ito Y, Warashina M, Terashima K, Sanosaka T, Nakashima K, Gage FH, Asashima M. Insulin biosynthesis in neuronal progenitors derived from adult hippocampus and the olfactory bulb. Embo Molecular Medicine. 3: 742-54. PMID 21984534 DOI: 10.1002/emmm.201100177  1
2011 Zhu Q, Pao GM, Huynh AM, Suh H, Tonnu N, Nederlof PM, Gage FH, Verma IM. BRCA1 tumour suppression occurs via heterochromatin-mediated silencing. Nature. 477: 179-84. PMID 21901007 DOI: 10.1038/nature10371  1
2011 Marchetto MC, Brennand KJ, Boyer LF, Gage FH. Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises. Human Molecular Genetics. 20: R109-15. PMID 21828073 DOI: 10.1093/hmg/ddr336  1
2011 Hester ME, Murtha MJ, Song S, Rao M, Miranda CJ, Meyer K, Tian J, Boulting G, Schaffer DV, Zhu MX, Pfaff SL, Gage FH, Kaspar BK. Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1905-12. PMID 21772256 DOI: 10.1038/mt.2011.135  1
2011 Shen B, Xiang Z, Miller B, Louie G, Wang W, Noel JP, Gage FH, Wang L. Genetically encoding unnatural amino acids in neural stem cells and optically reporting voltage-sensitive domain changes in differentiated neurons. Stem Cells (Dayton, Ohio). 29: 1231-40. PMID 21681861 DOI: 10.1002/stem.679  1
2011 Aimone JB, Deng W, Gage FH. Resolving new memories: a critical look at the dentate gyrus, adult neurogenesis, and pattern separation. Neuron. 70: 589-96. PMID 21609818 DOI: 10.1016/j.neuron.2011.05.010  1
2011 Woods NB, Parker AS, Moraghebi R, Lutz MK, Firth AL, Brennand KJ, Berggren WT, Raya A, Izpisúa Belmonte JC, Gage FH, Verma IM. Brief report: efficient generation of hematopoietic precursors and progenitors from human pluripotent stem cell lines. Stem Cells (Dayton, Ohio). 29: 1158-64. PMID 21544903 DOI: 10.1002/stem.657  1
2011 Brennand KJ, Simone A, Jou J, Gelboin-Burkhart C, Tran N, Sangar S, Li Y, Mu Y, Chen G, Yu D, McCarthy S, Sebat J, Gage FH. Modelling schizophrenia using human induced pluripotent stem cells. Nature. 473: 221-5. PMID 21490598 DOI: 10.1038/nature09915  1
2011 Mu Y, Zhao C, Gage FH. Dopaminergic modulation of cortical inputs during maturation of adult-born dentate granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4113-23. PMID 21411652 DOI: 10.1523/JNEUROSCI.4913-10.2011  1
2011 Yuan SH, Martin J, Elia J, Flippin J, Paramban RI, Hefferan MP, Vidal JG, Mu Y, Killian RL, Israel MA, Emre N, Marsala S, Marsala M, Gage FH, Goldstein LS, et al. Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells. Plos One. 6: e17540. PMID 21407814 DOI: 10.1371/journal.pone.0017540  1
2011 Aimone JB, Gage FH. Modeling new neuron function: a history of using computational neuroscience to study adult neurogenesis. The European Journal of Neuroscience. 33: 1160-9. PMID 21395860 DOI: 10.1111/j.1460-9568.2011.07615.x  1
2011 Winner B, Kohl Z, Gage FH. Neurodegenerative disease and adult neurogenesis. The European Journal of Neuroscience. 33: 1139-51. PMID 21395858 DOI: 10.1111/j.1460-9568.2011.07613.x  1
2011 Winner B, Jappelli R, Maji SK, Desplats PA, Boyer L, Aigner S, Hetzer C, Loher T, Vilar M, Campioni S, Tzitzilonis C, Soragni A, Jessberger S, Mira H, Consiglio A, ... ... Gage FH, et al. In vivo demonstration that alpha-synuclein oligomers are toxic. Proceedings of the National Academy of Sciences of the United States of America. 108: 4194-9. PMID 21325059 DOI: 10.1073/pnas.1100976108  1
2011 Kim JE, O'Sullivan ML, Sanchez CA, Hwang M, Israel MA, Brennand K, Deerinck TJ, Goldstein LS, Gage FH, Ellisman MH, Ghosh A. Investigating synapse formation and function using human pluripotent stem cell-derived neurons. Proceedings of the National Academy of Sciences of the United States of America. 108: 3005-10. PMID 21278334 DOI: 10.1073/pnas.1007753108  1
2011 Meng X, Arocena M, Penninger J, Gage FH, Zhao M, Song B. PI3K mediated electrotaxis of embryonic and adult neural progenitor cells in the presence of growth factors. Experimental Neurology. 227: 210-7. PMID 21092738 DOI: 10.1016/j.expneurol.2010.11.002  1
2010 Ruiz S, Brennand K, Panopoulos AD, Herrerías A, Gage FH, Izpisua-Belmonte JC. High-efficient generation of induced pluripotent stem cells from human astrocytes. Plos One. 5: e15526. PMID 21170306 DOI: 10.1371/journal.pone.0015526  1
2010 Muotri AR, Marchetto MC, Coufal NG, Oefner R, Yeo G, Nakashima K, Gage FH. L1 retrotransposition in neurons is modulated by MeCP2. Nature. 468: 443-6. PMID 21085180 DOI: 10.1038/nature09544  1
2010 Marchetto MC, Carromeu C, Acab A, Yu D, Yeo GW, Mu Y, Chen G, Gage FH, Muotri AR. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell. 143: 527-39. PMID 21074045 DOI: 10.1016/j.cell.2010.10.016  1
2010 Ma DK, Marchetto MC, Guo JU, Ming GL, Gage FH, Song H. Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nature Neuroscience. 13: 1338-44. PMID 20975758 DOI: 10.1038/nn.2672  1
2010 Mathews EA, Morgenstern NA, Piatti VC, Zhao C, Jessberger S, Schinder AF, Gage FH. A distinctive layering pattern of mouse dentate granule cells is generated by developmental and adult neurogenesis. The Journal of Comparative Neurology. 518: 4479-90. PMID 20886617 DOI: 10.1002/cne.22489  1
2010 Gage FH. Molecular and cellular mechanisms contributing to the regulation, proliferation and differentiation of neural stem cells in the adult dentate gyrus. The Keio Journal of Medicine. 59: 79-83. PMID 20881448  1
2010 Petruska JC, Kitay B, Boyce VS, Kaspar BK, Pearse DD, Gage FH, Mendell LM. Intramuscular AAV delivery of NT-3 alters synaptic transmission to motoneurons in adult rats. The European Journal of Neuroscience. 32: 997-1005. PMID 20849530 DOI: 10.1111/j.1460-9568.2010.07392.x  1
2010 Aimone JB, Deng W, Gage FH. Put them out to pasture? What are old granule cells good for, anyway...? Hippocampus. 20: 1124-5. PMID 20848611 DOI: 10.1002/hipo.20867  1
2010 Liu D, Ou L, Clemenson GD, Chao C, Lutske ME, Zambetti GP, Gage FH, Xu Y. Puma is required for p53-induced depletion of adult stem cells. Nature Cell Biology. 12: 993-8. PMID 20818388 DOI: 10.1038/ncb2100  1
2010 Mira H, Andreu Z, Suh H, Lie DC, Jessberger S, Consiglio A, San Emeterio J, Hortigüela R, Marqués-Torrejón MA, Nakashima K, Colak D, Götz M, Fariñas I, Gage FH. Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus. Cell Stem Cell. 7: 78-89. PMID 20621052 DOI: 10.1016/j.stem.2010.04.016  1
2010 Aimone JB, Deng W, Gage FH. Adult neurogenesis: integrating theories and separating functions. Trends in Cognitive Sciences. 14: 325-37. PMID 20471301 DOI: 10.1016/j.tics.2010.04.003  1
2010 Mu Y, Lee SW, Gage FH. Signaling in adult neurogenesis. Current Opinion in Neurobiology. 20: 416-23. PMID 20471243 DOI: 10.1016/j.conb.2010.04.010  1
2010 Singer T, McConnell MJ, Marchetto MC, Coufal NG, Gage FH. LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes? Trends in Neurosciences. 33: 345-54. PMID 20471112 DOI: 10.1016/j.tins.2010.04.001  1
2010 Marchetto MC, Winner B, Gage FH. Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases. Human Molecular Genetics. 19: R71-6. PMID 20418487 DOI: 10.1093/hmg/ddq159  1
2010 Tronel S, Fabre A, Charrier V, Oliet SH, Gage FH, Abrous DN. Spatial learning sculpts the dendritic arbor of adult-born hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 107: 7963-8. PMID 20375283 DOI: 10.1073/pnas.0914613107  1
2010 Deng W, Aimone JB, Gage FH. New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nature Reviews. Neuroscience. 11: 339-50. PMID 20354534 DOI: 10.1038/nrn2822  1
2010 Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH. Mechanisms underlying inflammation in neurodegeneration. Cell. 140: 918-34. PMID 20303880 DOI: 10.1016/j.cell.2010.02.016  1
2010 Qu Q, Sun G, Li W, Yang S, Ye P, Zhao C, Yu RT, Gage FH, Evans RM, Shi Y. Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal. Nature Cell Biology. 12: 31-40; sup pp 1-9. PMID 20010817 DOI: 10.1038/ncb2001  1
2009 Overall RW, Kempermann G, Peirce J, Lu L, Goldowitz D, Gage FH, Goodwin S, Smit AB, Airey DC, Rosen GD, Schalkwyk LC, Sutter TR, Nowakowski RS, Whatley S, Williams RW. Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource. Frontiers in Neuroscience. 3: 55. PMID 20582282 DOI: 10.3389/neuro.15.003.2009  1
2009 Nakashima K, Kohyama J, Namihira M, Gage FH, Okano H, Sawamoto K. [Epigenetic mechanisms regulating neural cell fate determination]. No to Hattatsu. Brain and Development. 41: 411-4. PMID 19928537  1
2009 Deng W, Saxe MD, Gallina IS, Gage FH. Adult-born hippocampal dentate granule cells undergoing maturation modulate learning and memory in the brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 13532-42. PMID 19864566 DOI: 10.1523/JNEUROSCI.3362-09.2009  1
2009 Jessberger S, Gage FH, Eisch AJ, Lagace DC. Making a neuron: Cdk5 in embryonic and adult neurogenesis. Trends in Neurosciences. 32: 575-82. PMID 19782409 DOI: 10.1016/j.tins.2009.07.002  1
2009 Muotri AR, Zhao C, Marchetto MC, Gage FH. Environmental influence on L1 retrotransposons in the adult hippocampus. Hippocampus. 19: 1002-7. PMID 19771587 DOI: 10.1002/hipo.20564  1
2009 Marchetto MC, Yeo GW, Kainohana O, Marsala M, Gage FH, Muotri AR. Transcriptional signature and memory retention of human-induced pluripotent stem cells. Plos One. 4: e7076. PMID 19763270 DOI: 10.1371/journal.pone.0007076  1
2009 Tamaki SJ, Jacobs Y, Dohse M, Capela A, Cooper JD, Reitsma M, He D, Tushinski R, Belichenko PV, Salehi A, Mobley W, Gage FH, Huhn S, Tsukamoto AS, Weissman IL, et al. Neuroprotection of host cells by human central nervous system stem cells in a mouse model of infantile neuronal ceroid lipofuscinosis. Cell Stem Cell. 5: 310-9. PMID 19733542 DOI: 10.1016/j.stem.2009.05.022  1
2009 Kuwabara T, Hsieh J, Muotri A, Yeo G, Warashina M, Lie DC, Moore L, Nakashima K, Asashima M, Gage FH. Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis. Nature Neuroscience. 12: 1097-105. PMID 19701198 DOI: 10.1038/nn.2360  1
2009 Coufal NG, Garcia-Perez JL, Peng GE, Yeo GW, Mu Y, Lovci MT, Morell M, O'Shea KS, Moran JV, Gage FH. L1 retrotransposition in human neural progenitor cells. Nature. 460: 1127-31. PMID 19657334 DOI: 10.1038/nature08248  1
2009 Suh H, Deng W, Gage FH. Signaling in adult neurogenesis. Annual Review of Cell and Developmental Biology. 25: 253-75. PMID 19575663 DOI: 10.1146/annurev.cellbio.042308.113256  1
2009 Jagasia R, Steib K, Englberger E, Herold S, Faus-Kessler T, Saxe M, Gage FH, Song H, Lie DC. GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7966-77. PMID 19553437 DOI: 10.1523/JNEUROSCI.1054-09.2009  1
2009 Li Y, Mu Y, Gage FH. Development of neural circuits in the adult hippocampus. Current Topics in Developmental Biology. 87: 149-74. PMID 19427519 DOI: 10.1016/S0070-2153(09)01205-8  1
2009 Andrews MR, Czvitkovich S, Dassie E, Vogelaar CF, Faissner A, Blits B, Gage FH, ffrench-Constant C, Fawcett JW. Alpha9 integrin promotes neurite outgrowth on tenascin-C and enhances sensory axon regeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5546-57. PMID 19403822 DOI: 10.1523/JNEUROSCI.0759-09.2009  1
2009 Saijo K, Winner B, Carson CT, Collier JG, Boyer L, Rosenfeld MG, Gage FH, Glass CK. A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell. 137: 47-59. PMID 19345186 DOI: 10.1016/j.cell.2009.01.038  1
2009 Denli AM, Cao X, Gage FH. miR-9 and TLX: chasing tails in neural stem cells. Nature Structural & Molecular Biology. 16: 346-7. PMID 19343066 DOI: 10.1038/nsmb0409-346  1
2009 Fortun J, Puzis R, Pearse DD, Gage FH, Bunge MB. Muscle injection of AAV-NT3 promotes anatomical reorganization of CST axons and improves behavioral outcome following SCI. Journal of Neurotrauma. 26: 941-53. PMID 19275471 DOI: 10.1089/neu.2008-0807  1
2009 Zhao C, Suh H, Gage FH. Notch keeps ependymal cells in line. Nature Neuroscience. 12: 243-5. PMID 19238183 DOI: 10.1038/nn0309-243  1
2009 Aimone JB, Wiles J, Gage FH. Computational influence of adult neurogenesis on memory encoding. Neuron. 61: 187-202. PMID 19186162 DOI: 10.1016/j.neuron.2008.11.026  1
2009 Jessberger S, Clark RE, Broadbent NJ, Clemenson GD, Consiglio A, Lie DC, Squire LR, Gage FH. Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats. Learning & Memory (Cold Spring Harbor, N.Y.). 16: 147-54. PMID 19181621 DOI: 10.1101/lm.1172609  1
2009 Rose JB, Crews L, Rockenstein E, Adame A, Mante M, Hersh LB, Gage FH, Spencer B, Potkar R, Marr RA, Masliah E. Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1115-25. PMID 19176820 DOI: 10.1523/JNEUROSCI.4220-08.2009  1
2009 Thuret S, Toni N, Aigner S, Yeo GW, Gage FH. Hippocampus-dependent learning is associated with adult neurogenesis in MRL/MpJ mice. Hippocampus. 19: 658-69. PMID 19140178 DOI: 10.1002/hipo.20550  1
2009 Yeo GW, Coufal NG, Liang TY, Peng GE, Fu XD, Gage FH. An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. Nature Structural & Molecular Biology. 16: 130-7. PMID 19136955 DOI: 10.1038/nsmb.1545  1
2009 Jessberger S, Gage FH. Fate plasticity of adult hippocampal progenitors: biological relevance and therapeutic use. Trends in Pharmacological Sciences. 30: 61-5. PMID 19135265 DOI: 10.1016/j.tips.2008.11.003  1
2009 Marumoto T, Tashiro A, Friedmann-Morvinski D, Scadeng M, Soda Y, Gage FH, Verma IM. Development of a novel mouse glioma model using lentiviral vectors. Nature Medicine. 15: 110-6. PMID 19122659 DOI: 10.1038/nm.1863  1
2008 Jessberger S, Gage FH. Stem-cell-associated structural and functional plasticity in the aging hippocampus. Psychology and Aging. 23: 684-91. PMID 19140640 DOI: 10.1037/a0014188  1
2008 Thompson CL, Pathak SD, Jeromin A, Ng LL, MacPherson CR, Mortrud MT, Cusick A, Riley ZL, Sunkin SM, Bernard A, Puchalski RB, Gage FH, Jones AR, Bajic VB, Hawrylycz MJ, et al. Genomic anatomy of the hippocampus. Neuron. 60: 1010-21. PMID 19109908 DOI: 10.1016/j.neuron.2008.12.008  1
2008 Marchetto MC, Muotri AR, Mu Y, Smith AM, Cezar GG, Gage FH. Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells. Cell Stem Cell. 3: 649-57. PMID 19041781 DOI: 10.1016/j.stem.2008.10.001  1
2008 Cao X, Pfaff SL, Gage FH. YAP regulates neural progenitor cell number via the TEA domain transcription factor. Genes & Development. 22: 3320-34. PMID 19015275 DOI: 10.1101/gad.1726608  1
2008 Spencer B, Marr RA, Rockenstein E, Crews L, Adame A, Potkar R, Patrick C, Gage FH, Verma IM, Masliah E. Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice. Bmc Neuroscience. 9: 109. PMID 19014502 DOI: 10.1186/1471-2202-9-109  1
2008 Kohyama J, Kojima T, Takatsuka E, Yamashita T, Namiki J, Hsieh J, Gage FH, Namihira M, Okano H, Sawamoto K, Nakashima K. Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain. Proceedings of the National Academy of Sciences of the United States of America. 105: 18012-7. PMID 19004774 DOI: 10.1073/pnas.0808417105  1
2008 Jessberger S, Aigner S, Clemenson GD, Toni N, Lie DC, Karalay O, Overall R, Kempermann G, Gage FH. Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus. Plos Biology. 6: e272. PMID 18998770 DOI: 10.1371/journal.pbio.0060272  1
2008 Li X, Barkho BZ, Luo Y, Smrt RD, Santistevan NJ, Liu C, Kuwabara T, Gage FH, Zhao X. Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells. The Journal of Biological Chemistry. 283: 27644-52. PMID 18689796 DOI: 10.1074/jbc.M804899200  1
2008 Yeo GW, Coufal N, Aigner S, Winner B, Scolnick JA, Marchetto MC, Muotri AR, Carson C, Gage FH. Multiple layers of molecular controls modulate self-renewal and neuronal lineage specification of embryonic stem cells. Human Molecular Genetics. 17: R67-75. PMID 18632700 DOI: 10.1093/hmg/ddn065  1
2008 Toni N, Laplagne DA, Zhao C, Lombardi G, Ribak CE, Gage FH, Schinder AF. Neurons born in the adult dentate gyrus form functional synapses with target cells. Nature Neuroscience. 11: 901-7. PMID 18622400 DOI: 10.1038/nn.2156  1
2008 Jessberger S, Toni N, Clemenson GD, Ray J, Gage FH. Directed differentiation of hippocampal stem/progenitor cells in the adult brain. Nature Neuroscience. 11: 888-93. PMID 18587391 DOI: 10.1038/nn.2148  1
2008 Zhao C, Deng W, Gage FH. Mechanisms and functional implications of adult neurogenesis. Cell. 132: 645-60. PMID 18295581 DOI: 10.1016/j.cell.2008.01.033  1
2007 Suh H, Consiglio A, Ray J, Sawai T, D'Amour KA, Gage FH. In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus. Cell Stem Cell. 1: 515-28. PMID 18371391 DOI: 10.1016/j.stem.2007.09.002  1
2007 Yeo GW, Xu X, Liang TY, Muotri AR, Carson CT, Coufal NG, Gage FH. Alternative splicing events identified in human embryonic stem cells and neural progenitors. Plos Computational Biology. 3: 1951-67. PMID 17967047 DOI: 10.1371/journal.pcbi.0030196  1
2007 Muotri AR, Marchetto MC, Coufal NG, Gage FH. The necessary junk: new functions for transposable elements. Human Molecular Genetics. 16: R159-67. PMID 17911158 DOI: 10.1093/hmg/ddm196  1
2007 Jessberger S, Zhao C, Toni N, Clemenson GD, Li Y, Gage FH. Seizure-associated, aberrant neurogenesis in adult rats characterized with retrovirus-mediated cell labeling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9400-7. PMID 17728453 DOI: 10.1523/JNEUROSCI.2002-07.2007  1
2007 Aigner S, Denli AM, Gage FH. A novel model for an older remodeler: the BAF swap in neurogenesis. Neuron. 55: 171-3. PMID 17640518 DOI: 10.1016/j.neuron.2007.07.004  1
2007 Jessberger S, Nakashima K, Clemenson GD, Mejia E, Mathews E, Ure K, Ogawa S, Sinton CM, Gage FH, Hsieh J. Epigenetic modulation of seizure-induced neurogenesis and cognitive decline. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5967-75. PMID 17537967 DOI: 10.1523/JNEUROSCI.0110-07.2007  1
2007 van Praag H, Lucero MJ, Yeo GW, Stecker K, Heivand N, Zhao C, Yip E, Afanador M, Schroeter H, Hammerstone J, Gage FH. Plant-derived flavanol (-)epicatechin enhances angiogenesis and retention of spatial memory in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5869-78. PMID 17537957 DOI: 10.1523/JNEUROSCI.0914-07.2007  1
2007 Smrt RD, Eaves-Egenes J, Barkho BZ, Santistevan NJ, Zhao C, Aimone JB, Gage FH, Zhao X. Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons. Neurobiology of Disease. 27: 77-89. PMID 17532643 DOI: 10.1016/j.nbd.2007.04.005  1
2007 Laplagne DA, Kamienkowski JE, Espósito MS, Piatti VC, Zhao C, Gage FH, Schinder AF. Similar GABAergic inputs in dentate granule cells born during embryonic and adult neurogenesis. The European Journal of Neuroscience. 25: 2973-81. PMID 17509085 DOI: 10.1111/j.1460-9568.2007.05549.x  1
2007 Toni N, Teng EM, Bushong EA, Aimone JB, Zhao C, Consiglio A, van Praag H, Martone ME, Ellisman MH, Gage FH. Synapse formation on neurons born in the adult hippocampus. Nature Neuroscience. 10: 727-34. PMID 17486101 DOI: 10.1038/nn1908  1
2007 Garcia-Perez JL, Marchetto MC, Muotri AR, Coufal NG, Gage FH, O'Shea KS, Moran JV. LINE-1 retrotransposition in human embryonic stem cells. Human Molecular Genetics. 16: 1569-77. PMID 17468180 DOI: 10.1093/hmg/ddm105  1
2007 Tashiro A, Makino H, Gage FH. Experience-specific functional modification of the dentate gyrus through adult neurogenesis: a critical period during an immature stage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3252-9. PMID 17376985 DOI: 10.1523/JNEUROSCI.4941-06.2007  1
2007 Jessberger S, Clemenson GD, Gage FH. Spontaneous fusion and nonclonal growth of adult neural stem cells. Stem Cells (Dayton, Ohio). 25: 871-4. PMID 17185607 DOI: 10.1634/stemcells.2006-0620  1
2006 Tashiro A, Zhao C, Gage FH. Retrovirus-mediated single-cell gene knockout technique in adult newborn neurons in vivo. Nature Protocols. 1: 3049-55. PMID 17406567 DOI: 10.1038/nprot.2006.473  1
2006 Miller TM, Kim SH, Yamanaka K, Hester M, Umapathi P, Arnson H, Rizo L, Mendell JR, Gage FH, Cleveland DW, Kaspar BK. Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 19546-51. PMID 17164329 DOI: 10.1073/pnas.0609411103  1
2006 Laplagne DA, Espósito MS, Piatti VC, Morgenstern NA, Zhao C, van Praag H, Gage FH, Schinder AF. Functional convergence of neurons generated in the developing and adult hippocampus. Plos Biology. 4: e409. PMID 17121455 DOI: 10.1371/journal.pbio.0040409  1
2006 Tashiro A, Sandler VM, Toni N, Zhao C, Gage FH. NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus. Nature. 442: 929-33. PMID 16906136 DOI: 10.1038/nature05028  1
2006 Jagasia R, Song H, Gage FH, Lie DC. New regulators in adult neurogenesis and their potential role for repair. Trends in Molecular Medicine. 12: 400-5. PMID 16890023 DOI: 10.1016/j.molmed.2006.07.006  0.96
2006 Horky LL, Galimi F, Gage FH, Horner PJ. Fate of endogenous stem/progenitor cells following spinal cord injury. The Journal of Comparative Neurology. 498: 525-38. PMID 16874803 DOI: 10.1002/cne.21065  1
2006 Barkho BZ, Song H, Aimone JB, Smrt RD, Kuwabara T, Nakashima K, Gage FH, Zhao X. Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation. Stem Cells and Development. 15: 407-21. PMID 16846377 DOI: 10.1089/scd.2006.15.407  1
2006 Aimone JB, Wiles J, Gage FH. Potential role for adult neurogenesis in the encoding of time in new memories. Nature Neuroscience. 9: 723-7. PMID 16732202 DOI: 10.1038/nn1707  1
2006 Yang H, Lu P, McKay HM, Bernot T, Keirstead H, Steward O, Gage FH, Edgerton VR, Tuszynski MH. Endogenous neurogenesis replaces oligodendrocytes and astrocytes after primate spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2157-66. PMID 16495442 DOI: 10.1523/JNEUROSCI.4070-05.2005  1
2006 Kempermann G, Chesler EJ, Lu L, Williams RW, Gage FH. Natural variation and genetic covariance in adult hippocampal neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 780-5. PMID 16407118 DOI: 10.1073/pnas.0510291103  1
2006 Zhao C, Teng EM, Summers RG, Ming GL, Gage FH. Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3-11. PMID 16399667 DOI: 10.1523/JNEUROSCI.3648-05.2006  1
2006 Borrell V, Kaspar BK, Gage FH, Callaway EM. In vivo evidence for radial migration of neurons by long-distance somal translocation in the developing ferret visual cortex. Cerebral Cortex (New York, N.Y. : 1991). 16: 1571-83. PMID 16357334 DOI: 10.1093/cercor/bhj094  1
2006 Pizzo DP, Coufal NG, Lortie MJ, Gage FH, Thal LJ. Regulatable acetylcholine-producing fibroblasts enhance cognitive performance. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 175-82. PMID 16185935 DOI: 10.1016/j.ymthe.2005.08.001  1
2005 Kuwabara T, Hsieh J, Nakashima K, Warashina M, Taira K, Gage FH. The NRSE smRNA specifies the fate of adult hippocampal neural stem cells. Nucleic Acids Symposium Series (2004). 87-8. PMID 17150646 DOI: 10.1093/nass/49.1.87  1
2005 Muotri AR, Nakashima K, Toni N, Sandler VM, Gage FH. Development of functional human embryonic stem cell-derived neurons in mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 102: 18644-8. PMID 16352714 DOI: 10.1073/pnas.0509315102  1
2005 Lie DC, Colamarino SA, Song HJ, Désiré L, Mira H, Consiglio A, Lein ES, Jessberger S, Lansford H, Dearie AR, Gage FH. Wnt signalling regulates adult hippocampal neurogenesis. Nature. 437: 1370-5. PMID 16251967 DOI: 10.1038/nature04108  1
2005 Hsieh J, Gage FH. Chromatin remodeling in neural development and plasticity. Current Opinion in Cell Biology. 17: 664-71. PMID 16226449 DOI: 10.1016/j.ceb.2005.09.002  1
2005 van Praag H, Shubert T, Zhao C, Gage FH. Exercise enhances learning and hippocampal neurogenesis in aged mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8680-5. PMID 16177036 DOI: 10.1523/JNEUROSCI.1731-05.2005  1
2005 Singer O, Marr RA, Rockenstein E, Crews L, Coufal NG, Gage FH, Verma IM, Masliah E. Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model. Nature Neuroscience. 8: 1343-9. PMID 16136043 DOI: 10.1038/nn1531  1
2005 Lin W, Dominguez B, Yang J, Aryal P, Brandon EP, Gage FH, Lee KF. Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism. Neuron. 46: 569-79. PMID 15944126 DOI: 10.1016/j.neuron.2005.04.002  1
2005 Kaspar BK, Frost LM, Christian L, Umapathi P, Gage FH. Synergy of insulin-like growth factor-1 and exercise in amyotrophic lateral sclerosis. Annals of Neurology. 57: 649-55. PMID 15852403 DOI: 10.1002/ana.20451  1
2005 Miller TM, Kaspar BK, Kops GJ, Yamanaka K, Christian LJ, Gage FH, Cleveland DW. Virus-delivered small RNA silencing sustains strength in amyotrophic lateral sclerosis. Annals of Neurology. 57: 773-6. PMID 15852369 DOI: 10.1002/ana.20453  1
2005 Myers CP, Lewcock JW, Hanson MG, Gosgnach S, Aimone JB, Gage FH, Lee KF, Landmesser LT, Pfaff SL. Cholinergic input is required during embryonic development to mediate proper assembly of spinal locomotor circuits. Neuron. 46: 37-49. PMID 15820692 DOI: 10.1016/j.neuron.2005.02.022  1
2005 Lein ES, Callaway EM, Albright TD, Gage FH. Redefining the boundaries of the hippocampal CA2 subfield in the mouse using gene expression and 3-dimensional reconstruction. The Journal of Comparative Neurology. 485: 1-10. PMID 15776443 DOI: 10.1002/cne.20426  1
2004 Hsieh J, Nakashima K, Kuwabara T, Mejia E, Gage FH. Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 16659-64. PMID 15537713 DOI: 10.1073/pnas.0407643101  1
2004 Schinder AF, Gage FH. A hypothesis about the role of adult neurogenesis in hippocampal function. Physiology (Bethesda, Md.). 19: 253-61. PMID 15381753 DOI: 10.1152/physiol.00012.2004  1
2004 Hsieh J, Gage FH. Epigenetic control of neural stem cell fate. Current Opinion in Genetics & Development. 14: 461-9. PMID 15380235 DOI: 10.1016/j.gde.2004.07.006  1
2004 Wurmser AE, Nakashima K, Summers RG, Toni N, D'Amour KA, Lie DC, Gage FH. Cell fusion-independent differentiation of neural stem cells to the endothelial lineage. Nature. 430: 350-6. PMID 15254537 DOI: 10.1038/nature02604  0.44
2004 Pizzo DP, Paban V, Coufal NG, Gage FH, Thal LJ. Long-term production of choline acetyltransferase in the CNS after transplantation of fibroblasts modified with a regulatable vector. Brain Research. Molecular Brain Research. 126: 1-13. PMID 15207910 DOI: 10.1016/j.molbrainres.2004.03.006  1
2004 Brandon EP, Mellott T, Pizzo DP, Coufal N, D'Amour KA, Gobeske K, Lortie M, López-Coviella I, Berse B, Thal LJ, Gage FH, Blusztajn JK. Choline transporter 1 maintains cholinergic function in choline acetyltransferase haploinsufficiency. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5459-66. PMID 15201317 DOI: 10.1523/JNEUROSCI.1106-04.2004  1
2004 Wurmser AE, Palmer TD, Gage FH. Neuroscience. Cellular interactions in the stem cell niche. Science (New York, N.Y.). 304: 1253-5. PMID 15166350 DOI: 10.1126/science.1099344  1
2004 Lein ES, Zhao X, Gage FH. Defining a molecular atlas of the hippocampus using DNA microarrays and high-throughput in situ hybridization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3879-89. PMID 15084669 DOI: 10.1523/JNEUROSCI.4710-03.2004  1
2004 Kempermann G, Wiskott L, Gage FH. Functional significance of adult neurogenesis. Current Opinion in Neurobiology. 14: 186-91. PMID 15082323 DOI: 10.1016/j.conb.2004.03.001  1
2004 Markakis EA, Palmer TD, Randolph-Moore L, Rakic P, Gage FH. Novel neuronal phenotypes from neural progenitor cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2886-97. PMID 15044527 DOI: 10.1523/JNEUROSCI.4161-03.2004  1
2004 Kuwabara T, Hsieh J, Nakashima K, Taira K, Gage FH. A small modulatory dsRNA specifies the fate of adult neural stem cells. Cell. 116: 779-93. PMID 15035981  1
2004 Aimone JB, Gage FH. Unbiased characterization of high-density oligonucleotide microarrays using probe-level statistics. Journal of Neuroscience Methods. 135: 27-33. PMID 15020086 DOI: 10.1016/j.jneumeth.2003.11.016  1
2004 Schaffer DV, Gage FH. Neurogenesis and neuroadaptation. Neuromolecular Medicine. 5: 1-9. PMID 15001808 DOI: 10.1385/NMM:5:1:001  1
2004 Lie DC, Song H, Colamarino SA, Ming GL, Gage FH. Neurogenesis in the adult brain: new strategies for central nervous system diseases. Annual Review of Pharmacology and Toxicology. 44: 399-421. PMID 14744252 DOI: 10.1146/annurev.pharmtox.44.101802.121631  1
2004 Hsieh J, Aimone JB, Kaspar BK, Kuwabara T, Nakashima K, Gage FH. IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes. The Journal of Cell Biology. 164: 111-22. PMID 14709544 DOI: 10.1083/jcb.200308101  1
2003 Aberg MA, Aberg ND, Palmer TD, Alborn AM, Carlsson-Skwirut C, Bang P, Rosengren LE, Olsson T, Gage FH, Eriksson PS. IGF-I has a direct proliferative effect in adult hippocampal progenitor cells. Molecular and Cellular Neurosciences. 24: 23-40. PMID 14550766 DOI: 10.1016/S1044-7431(03)00082-4  1
2003 Arvanian VL, Horner PJ, Gage FH, Mendell LM. Chronic neurotrophin-3 strengthens synaptic connections to motoneurons in the neonatal rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8706-12. PMID 14507970  1
2003 D'Amour KA, Gage FH. Genetic and functional differences between multipotent neural and pluripotent embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 11866-72. PMID 12923297 DOI: 10.1073/pnas.1834200100  1
2003 Kaspar BK, Lladó J, Sherkat N, Rothstein JD, Gage FH. Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model. Science (New York, N.Y.). 301: 839-42. PMID 12907804 DOI: 10.1126/science.1086137  1
2003 Dickinson-Anson H, Winkler J, Fisher LJ, Song HJ, Poo Mm, Gage FH. Acetylcholine-secreting cells improve age-induced memory deficits. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 51-61. PMID 12842428 DOI: 10.1016/S1525-0016(03)00145-X  1
2003 South SM, Kohno T, Kaspar BK, Hegarty D, Vissel B, Drake CT, Ohata M, Jenab S, Sailer AW, Malkmus S, Masuyama T, Horner P, Bogulavsky J, Gage FH, Yaksh TL, et al. A conditional deletion of the NR1 subunit of the NMDA receptor in adult spinal cord dorsal horn reduces NMDA currents and injury-induced pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5031-40. PMID 12832526  1
2003 Brown J, Cooper-Kuhn CM, Kempermann G, Van Praag H, Winkler J, Gage FH, Kuhn HG. Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis. The European Journal of Neuroscience. 17: 2042-6. PMID 12786970 DOI: 10.1046/j.1460-9568.2003.02647.x  1
2003 Zhao X, Ueba T, Christie BR, Barkho B, McConnell MJ, Nakashima K, Lein ES, Eadie BD, Willhoite AR, Muotri AR, Summers RG, Chun J, Lee KF, Gage FH. Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proceedings of the National Academy of Sciences of the United States of America. 100: 6777-82. PMID 12748381 DOI: 10.1073/pnas.1131928100  1
2003 Brandon EP, Lin W, D'Amour KA, Pizzo DP, Dominguez B, Sugiura Y, Thode S, Ko CP, Thal LJ, Gage FH, Lee KF. Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 539-49. PMID 12533614  1
2003 Lai K, Kaspar BK, Gage FH, Schaffer DV. Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo. Nature Neuroscience. 6: 21-7. PMID 12469128 DOI: 10.1038/nn983  1
2003 Kempermann G, Gast D, Kronenberg G, Yamaguchi M, Gage FH. Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice. Development (Cambridge, England). 130: 391-9. PMID 12466205 DOI: 10.1242/dev.00203  1
2002 Horner PJ, Thallmair M, Gage FH. Defining the NG2-expressing cell of the adult CNS. Journal of Neurocytology. 31: 469-80. PMID 14501217  0.92
2002 Zhao X, Gage FH. Expressing the central nervous system. Neurochemical Research. 27: 953-4. PMID 12462397 DOI: 10.1023/A:1020983805928  1
2002 Horner PJ, Gage FH. Regeneration in the adult and aging brain. Archives of Neurology. 59: 1717-20. PMID 12433257 DOI: 10.1001/archneur.59.11.1717  1
2002 Kempermann G, Gast D, Gage FH. Neuroplasticity in old age: sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment. Annals of Neurology. 52: 135-43. PMID 12210782 DOI: 10.1002/ana.10262  1
2002 Lie DC, Dziewczapolski G, Willhoite AR, Kaspar BK, Shults CW, Gage FH. The adult substantia nigra contains progenitor cells with neurogenic potential. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6639-49. PMID 12151543  1
2002 Song H, Stevens CF, Gage FH. Astroglia induce neurogenesis from adult neural stem cells. Nature. 417: 39-44. PMID 11986659 DOI: 10.1038/417039a  1
2002 Song HJ, Stevens CF, Gage FH. Neural stem cells from adult hippocampus develop essential properties of functional CNS neurons. Nature Neuroscience. 5: 438-45. PMID 11953752 DOI: 10.1038/nn844  1
2002 Kempermann G, Gage FH. Genetic influence on phenotypic differentiation in adult hippocampal neurogenesis. Brain Research. Developmental Brain Research. 134: 1-12. PMID 11947932 DOI: 10.1016/S0165-3806(01)00224-3  1
2002 van Praag H, Schinder AF, Christie BR, Toni N, Palmer TD, Gage FH. Functional neurogenesis in the adult hippocampus. Nature. 415: 1030-4. PMID 11875571 DOI: 10.1038/4151030a  1
2002 D'Amour KA, Gage FH. Are somatic stem cells pluripotent or lineage-restricted? Nature Medicine. 8: 213-4. PMID 11875484 DOI: 10.1038/nm0302-213  1
2002 Kaspar BK, Vissel B, Bengoechea T, Crone S, Randolph-Moore L, Muller R, Brandon EP, Schaffer D, Verma IM, Lee KF, Heinemann SF, Gage FH. Adeno-associated virus effectively mediates conditional gene modification in the brain. Proceedings of the National Academy of Sciences of the United States of America. 99: 2320-5. PMID 11842206 DOI: 10.1073/pnas.042678699  1
2002 Kaspar BK, Erickson D, Schaffer D, Hinh L, Gage FH, Peterson DA. Targeted retrograde gene delivery for neuronal protection. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 50-6. PMID 11786045 DOI: 10.1006/mthe.2001.0520  1
1989 Fischer W, Gage FH, Björklund A. Degenerative Changes in Forebrain Cholinergic Nuclei Correlate with Cognitive Impairments in Aged Rats. The European Journal of Neuroscience. 1: 34-45. PMID 12106172  1
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