Gary Aston-Jones - Publications

Affiliations: 
Medical University of South Carolina, Charleston, SC, United States 
Area:
neuropharmacology

243 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 James MH, Fragale JE, Aurora RN, Cooperman NA, Langleben DD, Aston-Jones G. Repurposing the dual orexin receptor antagonist suvorexant for the treatment of opioid use disorder: why sleep on this any longer? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31986520 DOI: 10.1038/s41386-020-0619-x  0.8
2020 James MH, Aston-Jones G. Introduction to the Special Issue: "Orexin/hypocretin receptor antagonists for the treatment of addiction and related psychiatric disease: What are the steps from here?" Brain Research. 146665. PMID 31930996 DOI: 10.1016/j.brainres.2020.146665  0.8
2019 Gu Y, Piper WT, Branigan LA, Vazey EM, Aston-Jones G, Lin L, LeDoux JE, Sears RM. A brainstem-central amygdala circuit underlies defensive responses to learned threats. Molecular Psychiatry. PMID 31758092 DOI: 10.1038/s41380-019-0599-6  1
2019 Hamlett ED, Ledreux A, Gilmore A, Vazey EM, Aston-Jones G, Boger HA, Paredes D, Granholm AE. Inhibitory designer receptors aggravate memory loss in a mouse model of down syndrome. Neurobiology of Disease. 134: 104616. PMID 31678403 DOI: 10.1016/j.nbd.2019.104616  1
2019 Mohammadkhani A, Fragale JE, Pantazis CB, Bowrey HE, James MH, Aston-Jones G. Orexin-1 receptor signaling in ventral pallidum regulates motivation for the opioid remifentanil. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31641055 DOI: 10.1523/JNEUROSCI.0255-19.2019  0.8
2019 Mohammadkhani A, James MH, Pantazis CB, Aston-Jones G. Persistent effects of the orexin-1 receptor antagonist SB-334867 on motivation for the fast acting opioid remifentanil. Brain Research. 146461. PMID 31526801 DOI: 10.1016/j.brainres.2019.146461  0.8
2019 Pantazis CB, James MH, Bentzley BS, Aston-Jones G. The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand. Addiction Biology. e12795. PMID 31297913 DOI: 10.1111/adb.12795  1
2019 Fragale JE, Pantazis CB, James MH, Aston-Jones G. The role of orexin-1 receptor signaling in demand for the opioid fentanyl. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31112988 DOI: 10.1038/s41386-019-0420-x  0.8
2019 Wiskerke J, James MH, Aston-Jones G. The orexin-1 receptor antagonist SB-334867 reduces motivation, but not inhibitory control, in a rat stop signal task. Brain Research. PMID 31002819 DOI: 10.1016/j.brainres.2019.04.017  0.8
2019 Pantazis CB, Aston-Jones G. Lateral septum inhibition reduces motivation for cocaine: Reversal by diazepam. Addiction Biology. PMID 30896079 DOI: 10.1111/adb.12742  0.56
2018 Mahler SV, Brodnik ZD, Cox BM, Buchta WC, Bentzley BS, Quintanilla J, Cope ZA, Lin EC, Riedy MD, Scofield MD, Messinger J, Ruiz CM, Riegel AC, España RA, Aston-Jones G. Chemogenetic Manipulations of Ventral Tegmental Area Dopamine Neurons Reveal Multifaceted Roles in Cocaine Abuse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30446532 DOI: 10.1523/JNEUROSCI.0537-18.2018  1
2018 Swift KM, Gross BA, Frazer MA, Bauer DS, Clark KJD, Vazey EM, Aston-Jones G, Li Y, Pickering AE, Sara SJ, Poe GR. Abnormal Locus Coeruleus Sleep Activity Alters Sleep Signatures of Memory Consolidation and Impairs Place Cell Stability and Spatial Memory. Current Biology : Cb. PMID 30393040 DOI: 10.1016/j.cub.2018.09.054  1
2018 Yeoh JW, James MH, Adams CD, Bains JS, Sakurai T, Aston-Jones G, Graham BA, Dayas CV. Activation of lateral hypothalamic group III mGluRs suppresses cocaine-seeking following abstinence and normalizes drug-associated increases in excitatory drive to orexin/hypocretin cells. Neuropharmacology. PMID 30253175 DOI: 10.1016/j.neuropharm.2018.09.033  0.8
2018 James MH, Bowrey HE, Stopper CM, Aston-Jones G. Demand elasticity predicts addiction endophenotypes and the therapeutic efficacy of an orexin/hypocretin-1 receptor antagonist in rats. The European Journal of Neuroscience. PMID 30240516 DOI: 10.1111/ejn.14166  0.8
2018 Vazey EM, Moorman DE, Aston-Jones G. Phasic locus coeruleus activity regulates cortical encoding of salience information. Proceedings of the National Academy of Sciences of the United States of America. PMID 30232259 DOI: 10.1073/pnas.1803716115  1
2018 James MH, Stopper CM, Zimmer BA, Koll NE, Bowrey HE, Aston-Jones G. Increased Number and Activity of a Lateral Subpopulation of Hypothalamic Orexin/Hypocretin Neurons Underlies the Expression of an Addicted State in Rats. Biological Psychiatry. PMID 30219208 DOI: 10.1016/j.biopsych.2018.07.022  0.8
2018 Kohtz AS, Lin B, Smith ME, Aston-Jones G. Attenuated cocaine-seeking after oxytocin administration in male and female rats. Psychopharmacology. PMID 29671014 DOI: 10.1007/s00213-018-4902-z  1
2018 Mahler SV, Aston-Jones G. CNO Evil? Considerations for the Use of DREADDs in Behavioral Neuroscience. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29303143 DOI: 10.1038/npp.2017.299  1
2017 James MH, McGlinchey EM, Vattikonda A, Mahler SV, Aston-Jones G. Cued reinstatement of cocaine- but not sucrose-seeking is dependent upon dopamine signaling in prelimbic cortex and is associated with recruitment of prelimbic neurons that project to contralateral nucleus accumbens core. The International Journal of Neuropsychopharmacology. PMID 29165565 DOI: 10.1093/ijnp/pyx107  1
2017 Campese VD, Soroeta JM, Vazey EM, Aston-Jones G, LeDoux JE, Sears RM. Noradrenergic Regulation of Central Amygdala in Aversive Pavlovian-to-Instrumental Transfer. Eneuro. 4. PMID 29071299 DOI: 10.1523/ENEURO.0224-17.2017  1
2017 Kane GA, Vazey EM, Wilson RC, Shenhav A, Daw ND, Aston-Jones G, Cohen JD. Increased locus coeruleus tonic activity causes disengagement from a patch-foraging task. Cognitive, Affective & Behavioral Neuroscience. PMID 28900892 DOI: 10.3758/s13415-017-0531-y  1
2017 McGlinchey EM, Aston-Jones G. Dorsal Hippocampus Drives Context-Induced Cocaine Seeking via Inputs to Lateral Septum. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28695893 DOI: 10.1038/npp.2017.144  0.72
2017 Bowrey HE, James MH, Aston-Jones G. New directions for the treatment of depression: Targeting the photic regulation of arousal and mood (PRAM) pathway. Depression and Anxiety. PMID 28489327 DOI: 10.1002/da.22635  0.8
2017 Buchta WC, Mahler SV, Harlan B, Aston-Jones GS, Riegel AC. Dopamine terminals from the ventral tegmental area gate intrinsic inhibition in the prefrontal cortex. Physiological Reports. 5. PMID 28325790 DOI: 10.14814/phy2.13198  1
2017 James MH, Aston-Jones G. Orexin/Hypocretin, Central Amygdala, and Escalation of Cocaine Intake. Biological Psychiatry. 81: 552-553. PMID 28283054 DOI: 10.1016/j.biopsych.2017.01.010  0.8
2017 McRae-Clark AL, Cason AM, Kohtz AS, Moran Santa-Maria M, Aston-Jones G, Brady KT. Impact of gender on corticotropin-releasing factor and noradrenergic sensitivity in cocaine use disorder. Journal of Neuroscience Research. 95: 320-327. PMID 27870396 DOI: 10.1002/jnr.23860  1
2016 Cox BM, Bentzley BS, Regen-Tuero H, See RE, Reichel CM, Aston-Jones G. Oxytocin Acts in Nucleus Accumbens to Attenuate Methamphetamine Seeking and Demand. Biological Psychiatry. PMID 28110822 DOI: 10.1016/j.biopsych.2016.11.011  1
2016 James MH, Mahler SV, Moorman DE, Aston-Jones G. A Decade of Orexin/Hypocretin and Addiction: Where Are We Now? Current Topics in Behavioral Neurosciences. PMID 28012090 DOI: 10.1007/7854_2016_57  1
2016 Moorman DE, James MH, Kilroy EA, Aston-Jones G. Orexin/hypocretin-1 receptor antagonism reduces ethanol self-administration and reinstatement selectively in highly-motivated rats. Brain Research. PMID 27771284 DOI: 10.1016/j.brainres.2016.10.018  1
2016 James MH, Aston-Jones G. The Ventral Pallidum: Proposed Integrator of Positive and Negative Factors in Cocaine Abuse. Neuron. 92: 5-8. PMID 27710789 DOI: 10.1016/j.neuron.2016.09.042  0.8
2016 Augur IF, Wyckoff AR, Aston-Jones G, Kalivas PW, Peters J. Chemogenetic Activation of an Extinction Neural Circuit Reduces Cue-Induced Reinstatement of Cocaine Seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 10174-80. PMID 27683912 DOI: 10.1523/JNEUROSCI.0773-16.2016  0.68
2016 McGlinchey EM, James MH, Mahler SV, Pantazis C, Aston-Jones G. Prelimbic to Accumbens Core Pathway Is Recruited in a Dopamine-Dependent Manner to Drive Cued Reinstatement of Cocaine Seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8700-11. PMID 27535915 DOI: 10.1523/JNEUROSCI.1291-15.2016  1
2016 Kohtz AS, Aston-Jones G. Cocaine Seeking during Initial Abstinence is Driven by Noradrenergic and Serotonergic Signaling in Hippocampus in a Sex-Dependent Manner. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27515792 DOI: 10.1038/npp.2016.150  1
2016 Cason AM, Kohtz A, Aston-Jones G. Role of Corticotropin Releasing Factor 1 Signaling in Cocaine Seeking during Early Extinction in Female and Male Rats. Plos One. 11: e0158577. PMID 27362504 DOI: 10.1371/journal.pone.0158577  0.72
2016 Cox BM, Cope ZA, Parsegian A, Floresco SB, Aston-Jones G, See RE. Chronic methamphetamine self-administration alters cognitive flexibility in male rats. Psychopharmacology. PMID 27037939 DOI: 10.1007/s00213-016-4283-0  0.96
2016 Bentzley BS, Aston-Jones G. Inhibiting subthalamic nucleus decreases cocaine demand and relapse: therapeutic potential. Addiction Biology. PMID 26935125 DOI: 10.1111/adb.12380  1
2016 Lopez MF, Moorman DE, Aston-Jones G, Becker HC. The highly selective orexin/hypocretin 1 receptor antagonist GSK1059865 potently reduces ethanol drinking in ethanol dependent mice. Brain Research. PMID 26851547 DOI: 10.1016/j.brainres.2016.01.049  0.52
2016 Moorman DE, James MH, Kilroy EA, Aston-Jones G. Orexin/hypocretin neuron activation is correlated with alcohol seeking and preference in a topographically specific manner. The European Journal of Neuroscience. PMID 26750264 DOI: 10.1111/ejn.13170  0.52
2015 Porter-Stransky KA, Bentzley BS, Aston-Jones G. Individual differences in orexin-I receptor modulation of motivation for the opioid remifentanil. Addiction Biology. PMID 26598295 DOI: 10.1111/adb.12323  1
2015 Moorman DE, Aston-Jones G. Prefrontal neurons encode context-based response execution and inhibition in reward seeking and extinction. Proceedings of the National Academy of Sciences of the United States of America. 112: 9472-7. PMID 26170333 DOI: 10.1073/pnas.1507611112  1
2015 Keren NI, Taheri S, Vazey EM, Morgan PS, Granholm AC, Aston-Jones GS, Eckert MA. Histologic validation of locus coeruleus MRI contrast in post-mortem tissue. Neuroimage. 113: 235-45. PMID 25791783 DOI: 10.1016/j.neuroimage.2015.03.020  1
2015 Bentzley BS, Aston-Jones G. Orexin-1 receptor signaling increases motivation for cocaine-associated cues. The European Journal of Neuroscience. 41: 1149-56. PMID 25754681 DOI: 10.1111/ejn.12866  1
2015 Fortress AM, Hamlett ED, Vazey EM, Aston-Jones G, Cass WA, Boger HA, Granholm AC. Designer receptors enhance memory in a mouse model of Down syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 1343-53. PMID 25632113 DOI: 10.1523/JNEUROSCI.2658-14.2015  1
2015 Kaufling J, Aston-Jones G. Persistent adaptations in afferents to ventral tegmental dopamine neurons after opiate withdrawal Journal of Neuroscience. 35: 10290-10303. DOI: 10.1523/JNEUROSCI.0715-15.2015  1
2015 Moorman DE, Aston-Jones G. Prefrontal neurons encode context-based response execution and inhibition in reward seeking and extinction Proceedings of the National Academy of Sciences of the United States of America. 112: 9472-9477. DOI: 10.1073/pnas.1507611112  1
2014 Moorman DE, James MH, McGlinchey EM, Aston-Jones G. Differential roles of medial prefrontal subregions in the regulation of drug seeking. Brain Research. PMID 25529632 DOI: 10.1016/j.brainres.2014.12.024  1
2014 Mahler SV, Moorman DE, Smith RJ, James MH, Aston-Jones G. Motivational activation: a unifying hypothesis of orexin/hypocretin function. Nature Neuroscience. 17: 1298-303. PMID 25254979 DOI: 10.1038/nn.3810  1
2014 Moorman DE, Aston-Jones G. Orbitofrontal cortical neurons encode expectation-driven initiation of reward-seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 10234-46. PMID 25080585 DOI: 10.1523/JNEUROSCI.3216-13.2014  1
2014 Bentzley BS, Jhou TC, Aston-Jones G. Economic demand predicts addiction-like behavior and therapeutic efficacy of oxytocin in the rat. Proceedings of the National Academy of Sciences of the United States of America. 111: 11822-7. PMID 25071176 DOI: 10.1073/pnas.1406324111  1
2014 Cason AM, Aston-Jones G. Role of orexin/hypocretin in conditioned sucrose-seeking in female rats. Neuropharmacology. 86: 97-102. PMID 25036612 DOI: 10.1016/j.neuropharm.2014.07.007  1
2014 Vazey EM, Aston-Jones G. Designer receptors: therapeutic adjuncts to cell replacement therapy in Parkinson's disease. The Journal of Clinical Investigation. 124: 2858-60. PMID 24937425 DOI: 10.1172/JCI76833  1
2014 Mahler SV, Vazey EM, Beckley JT, Keistler CR, McGlinchey EM, Kaufling J, Wilson SP, Deisseroth K, Woodward JJ, Aston-Jones G. Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking. Nature Neuroscience. 17: 577-85. PMID 24584054 DOI: 10.1038/nn.3664  1
2014 Vazey EM, Aston-Jones G. Designer receptor manipulations reveal a role of the locus coeruleus noradrenergic system in isoflurane general anesthesia. Proceedings of the National Academy of Sciences of the United States of America. 111: 3859-64. PMID 24567395 DOI: 10.1073/pnas.1310025111  1
2014 Sartor GC, Aston-Jones G. Post-retrieval extinction attenuates cocaine memories. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1059-65. PMID 24257156 DOI: 10.1038/npp.2013.323  1
2014 Smith RJ, Aston-Jones G. Incentive learning for morphine-associated stimuli during protracted abstinence increases conditioned drug preference. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 373-9. PMID 23942418 DOI: 10.1038/npp.2013.200  1
2014 Mahler SV, Hensley-Simon M, Tahsili-Fahadan P, LaLumiere RT, Thomas C, Fallon RV, Kalivas PW, Aston-Jones G. Modafinil attenuates reinstatement of cocaine seeking: role for cystine-glutamate exchange and metabotropic glutamate receptors. Addiction Biology. 19: 49-60. PMID 23017017 DOI: 10.1111/j.1369-1600.2012.00506.x  1
2013 Cason AM, Aston-Jones G. Attenuation of saccharin-seeking in rats by orexin/hypocretin receptor 1 antagonist. Psychopharmacology. 228: 499-507. PMID 23494235 DOI: 10.1007/s00213-013-3051-7  1
2013 Aston-Jones G, Deisseroth K. Recent advances in optogenetics and pharmacogenetics. Brain Research. 1511: 1-5. PMID 23422677 DOI: 10.1016/j.brainres.2013.01.026  1
2013 Vazey EM, Aston-Jones G. New tricks for old dogmas: optogenetic and designer receptor insights for Parkinson's disease. Brain Research. 1511: 153-63. PMID 23337619 DOI: 10.1016/j.brainres.2013.01.021  1
2013 Cason AM, Aston-Jones G. Role of orexin/hypocretin in conditioned sucrose-seeking in rats. Psychopharmacology. 226: 155-65. PMID 23096770 DOI: 10.1007/s00213-012-2902-y  1
2013 Bentzley BS, Fender KM, Aston-Jones G. The behavioral economics of drug self-administration: a review and new analytical approach for within-session procedures. Psychopharmacology. 226: 113-25. PMID 23086021 DOI: 10.1007/s00213-012-2899-2  1
2013 Bari A, Aston-Jones G. Atomoxetine modulates spontaneous and sensory-evoked discharge of locus coeruleus noradrenergic neurons. Neuropharmacology. 64: 53-64. PMID 22820275 DOI: 10.1016/j.neuropharm.2012.07.020  1
2013 Mahler SV, Smith RJ, Aston-Jones G. Interactions between VTA orexin and glutamate in cue-induced reinstatement of cocaine seeking in rats. Psychopharmacology. 226: 687-98. PMID 22411428 DOI: 10.1007/s00213-012-2681-5  1
2013 Aston-Jones G, Mahler S, Sartor G, Smith R, Moorman D. Seeking reward: Upstream modulation of VTA dopamine neurons by orexin/hypocretin inputs Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 173-174. DOI: 10.1016/B978-0-12-800044-1.00153-7  1
2012 Sartor GC, Aston-Jones G. Regulation of the ventral tegmental area by the bed nucleus of the stria terminalis is required for expression of cocaine preference. The European Journal of Neuroscience. 36: 3549-58. PMID 23039920 DOI: 10.1111/j.1460-9568.2012.08277.x  1
2012 Mahler SV, Aston-Jones GS. Fos activation of selective afferents to ventral tegmental area during cue-induced reinstatement of cocaine seeking in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 13309-26. PMID 22993446 DOI: 10.1523/JNEUROSCI.2277-12.2012  1
2012 Zhou L, Smith RJ, Do PH, Aston-Jones G, See RE. Repeated orexin 1 receptor antagonism effects on cocaine seeking in rats. Neuropharmacology. 63: 1201-7. PMID 22971541 DOI: 10.1016/j.neuropharm.2012.07.044  1
2012 Vazey EM, Aston-Jones G. The emerging role of norepinephrine in cognitive dysfunctions of Parkinson's disease. Frontiers in Behavioral Neuroscience. 6: 48. PMID 22848194 DOI: 10.3389/fnbeh.2012.00048  1
2012 Mahler SV, Smith RJ, Moorman DE, Sartor GC, Aston-Jones G. Multiple roles for orexin/hypocretin in addiction. Progress in Brain Research. 198: 79-121. PMID 22813971 DOI: 10.1016/B978-0-444-59489-1.00007-0  1
2012 Sartor GC, Aston-Jones GS. A septal-hypothalamic pathway drives orexin neurons, which is necessary for conditioned cocaine preference. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4623-31. PMID 22457508 DOI: 10.1523/JNEUROSCI.4561-11.2012  1
2012 Richardson KA, Aston-Jones G. Lateral hypothalamic orexin/hypocretin neurons that project to ventral tegmental area are differentially activated with morphine preference. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3809-17. PMID 22423101 DOI: 10.1523/JNEUROSCI.3917-11.2012  1
2012 Smith RJ, Aston-Jones G. Orexin / hypocretin 1 receptor antagonist reduces heroin self-administration and cue-induced heroin seeking. The European Journal of Neuroscience. 35: 798-804. PMID 22356621 DOI: 10.1111/j.1460-9568.2012.08013.x  1
2012 Reissner KJ, Sartor GC, Vazey EM, Dunn TE, Aston-Jones G, Kalivas PW. Use of vivo-morpholinos for control of protein expression in the adult rat brain. Journal of Neuroscience Methods. 203: 354-60. PMID 22027492 DOI: 10.1016/j.jneumeth.2011.10.009  1
2011 Smith RJ, Aston-Jones G. α(2) Adrenergic and imidazoline receptor agonists prevent cue-induced cocaine seeking. Biological Psychiatry. 70: 712-9. PMID 21783176 DOI: 10.1016/j.biopsych.2011.06.010  1
2011 Luo AH, Tahsili-Fahadan P, Wise RA, Lupica CR, Aston-Jones G. Linking context with reward: a functional circuit from hippocampal CA3 to ventral tegmental area. Science (New York, N.Y.). 333: 353-7. PMID 21764750 DOI: 10.1126/science.1204622  1
2011 Lockrow J, Boger H, Gerhardt G, Aston-Jones G, Bachman D, Granholm AC. A noradrenergic lesion exacerbates neurodegeneration in a Down syndrome mouse model. Journal of Alzheimer's Disease : Jad. 23: 471-89. PMID 21098982 DOI: 10.3233/JAD-2010-101218  1
2011 Nieuwenhuis S, De Geus EJ, Aston-Jones G. The anatomical and functional relationship between the P3 and autonomic components of the orienting response. Psychophysiology. 48: 162-75. PMID 20557480 DOI: 10.1111/j.1469-8986.2010.01057.x  1
2010 Moorman DE, Aston-Jones G. Orexin/hypocretin modulates response of ventral tegmental dopamine neurons to prefrontal activation: diurnal influences. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15585-99. PMID 21084614 DOI: 10.1523/JNEUROSCI.2871-10.2010  1
2010 Tahsili-Fahadan P, Carr GV, Harris GC, Aston-Jones G. Modafinil blocks reinstatement of extinguished opiate-seeking in rats: mediation by a glutamate mechanism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2203-10. PMID 20631691 DOI: 10.1038/npp.2010.94  1
2010 Gompf HS, Greenberg JH, Aston-Jones G, Ianculescu AG, Scanlan TS, Dratman MB. 3-Monoiodothyronamine: the rationale for its action as an endogenous adrenergic-blocking neuromodulator. Brain Research. 1351: 130-40. PMID 20615397 DOI: 10.1016/j.brainres.2010.06.067  1
2010 Cason AM, Smith RJ, Tahsili-Fahadan P, Moorman DE, Sartor GC, Aston-Jones G. Role of orexin/hypocretin in reward-seeking and addiction: implications for obesity. Physiology & Behavior. 100: 419-28. PMID 20338186 DOI: 10.1016/j.physbeh.2010.03.009  1
2010 Valentino R, Aston-Jones G. Special issue on neuropeptides in stress and addiction: Overview. Brain Research. 1314: 1-2. PMID 20141765 DOI: 10.1016/j.brainres.2010.01.028  1
2010 Tahsili-Fahadan P, Malcolm R, Aston-Jones G. Modafinil: an anti-relapse medication. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 343-4. PMID 20010710 DOI: 10.1038/npp.2009.123  1
2010 Aston-Jones G, Smith RJ, Sartor GC, Moorman DE, Massi L, Tahsili-Fahadan P, Richardson KA. Lateral hypothalamic orexin/hypocretin neurons: A role in reward-seeking and addiction. Brain Research. 1314: 74-90. PMID 19815001 DOI: 10.1016/j.brainres.2009.09.106  1
2010 George MS, Aston-Jones G. Noninvasive techniques for probing neurocircuitry and treating illness: vagus nerve stimulation (VNS), transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS). Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 301-16. PMID 19693003 DOI: 10.1038/npp.2009.87  1
2010 Smith RJ, Tahsili-Fahadan P, Aston-Jones G. Orexin/hypocretin is necessary for context-driven cocaine-seeking. Neuropharmacology. 58: 179-84. PMID 19591850 DOI: 10.1016/j.neuropharm.2009.06.042  1
2010 Aston-Jones G, Meijas-Aponte CA, Waterhouse B. Norepinephrine: CNS pathways and neurophysiology Encyclopedia of Neuroscience. 1237-1248. DOI: 10.1016/B978-008045046-9.01153-0  1
2009 Gompf H, Chen J, Sun Y, Yanagisawa M, Aston-Jones G, Kelz MB. Halothane-induced hypnosis is not accompanied by inactivation of orexinergic output in rodents. Anesthesiology. 111: 1001-9. PMID 19809293 DOI: 10.1097/ALN.0b013e3181b764b3  1
2009 Moorman DE, Aston-Jones G. Orexin-1 receptor antagonism decreases ethanol consumption and preference selectively in high-ethanol--preferring Sprague--Dawley rats. Alcohol (Fayetteville, N.Y.). 43: 379-86. PMID 19671464 DOI: 10.1016/j.alcohol.2009.07.002  1
2009 Smith RJ, See RE, Aston-Jones G. Orexin/hypocretin signaling at the orexin 1 receptor regulates cue-elicited cocaine-seeking. The European Journal of Neuroscience. 30: 493-503. PMID 19656173 DOI: 10.1111/j.1460-9568.2009.06844.x  1
2009 Smith RJ, Aston-Jones G. Inactivating the activated: identifying functions of specific neural networks. Nature Neuroscience. 12: 965-6. PMID 19636350 DOI: 10.1038/nn0809-965  1
2009 Jalabert M, Aston-Jones G, Herzog E, Manzoni O, Georges F. Role of the bed nucleus of the stria terminalis in the control of ventral tegmental area dopamine neurons. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 33: 1336-46. PMID 19616054 DOI: 10.1016/j.pnpbp.2009.07.010  1
2009 Moorman DE, Aston-Jones G. Neuroscience: Optical control of reward. Nature. 458: 980-1. PMID 19396134 DOI: 10.1038/458980a  1
2009 Mejías-Aponte CA, Drouin C, Aston-Jones G. Adrenergic and noradrenergic innervation of the midbrain ventral tegmental area and retrorubral field: prominent inputs from medullary homeostatic centers. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3613-26. PMID 19295165 DOI: 10.1523/JNEUROSCI.4632-08.2009  1
2009 Aston-Jones G, Gold JI. How we say no: norepinephrine, inferior frontal gyrus, and response inhibition. Biological Psychiatry. 65: 548-9. PMID 19281881 DOI: 10.1016/j.biopsych.2009.01.022  1
2009 Luo AH, Aston-Jones G. Circuit projection from suprachiasmatic nucleus to ventral tegmental area: a novel circadian output pathway. The European Journal of Neuroscience. 29: 748-60. PMID 19200068 DOI: 10.1111/j.1460-9568.2008.06606.x  1
2009 Aston-Jones G, Smith RJ, Moorman DE, Richardson KA. Role of lateral hypothalamic orexin neurons in reward processing and addiction. Neuropharmacology. 56: 112-21. PMID 18655797 DOI: 10.1016/j.neuropharm.2008.06.060  1
2008 Smith RJ, Aston-Jones G. Noradrenergic transmission in the extended amygdala: role in increased drug-seeking and relapse during protracted drug abstinence. Brain Structure & Function. 213: 43-61. PMID 18651175 DOI: 10.1007/s00429-008-0191-3  1
2008 Gompf HS, Aston-Jones G. Role of orexin input in the diurnal rhythm of locus coeruleus impulse activity. Brain Research. 1224: 43-52. PMID 18614159 DOI: 10.1016/j.brainres.2008.05.060  1
2008 Aston-Jones G, Kalivas PW. Brain norepinephrine rediscovered in addiction research. Biological Psychiatry. 63: 1005-6. PMID 18482610 DOI: 10.1016/j.biopsych.2008.03.016  1
2008 Gonzalez MM, Aston-Jones G. Light deprivation damages monoamine neurons and produces a depressive behavioral phenotype in rats. Proceedings of the National Academy of Sciences of the United States of America. 105: 4898-903. PMID 18347342 DOI: 10.1073/pnas.0703615105  1
2008 Luo AH, Georges FE, Aston-Jones GS. Novel neurons in ventral tegmental area fire selectively during the active phase of the diurnal cycle. The European Journal of Neuroscience. 27: 408-22. PMID 18215237 DOI: 10.1111/j.1460-9568.2007.05985.x  1
2007 Zhu Y, Fenik P, Zhan G, Mazza E, Kelz M, Aston-Jones G, Veasey SC. Selective loss of catecholaminergic wake active neurons in a murine sleep apnea model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10060-71. PMID 17855620 DOI: 10.1523/JNEUROSCI.0857-07.2007  1
2007 Harris GC, Wimmer M, Randall-Thompson JF, Aston-Jones G. Lateral hypothalamic orexin neurons are critically involved in learning to associate an environment with morphine reward. Behavioural Brain Research. 183: 43-51. PMID 17599478 DOI: 10.1016/j.bbr.2007.05.025  1
2007 Harris GC, Hummel M, Wimmer M, Mague SD, Aston-Jones G. Elevations of FosB in the nucleus accumbens during forced cocaine abstinence correlate with divergent changes in reward function. Neuroscience. 147: 583-91. PMID 17560044 DOI: 10.1016/j.neuroscience.2007.04.050  1
2007 Harris GC, Aston-Jones G. Activation in extended amygdala corresponds to altered hedonic processing during protracted morphine withdrawal. Behavioural Brain Research. 176: 251-8. PMID 17123639 DOI: 10.1016/j.bbr.2006.10.012  1
2007 Aston-Jones G, Iba M, Clayton E, Rajkowski J, Cohen J. The locus coeruleus and regulation of behavioral flexibility and attention: Clinical implications Brain Norepinephrine: Neurobiology and Therapeutics. 196-235. DOI: 10.1017/CBO9780511544156.008  1
2007 Aston-Jones G, Gonzalez M, Doran S. Role of the locus coeruleus-norepinephrine system in arousal and circadian regulation of the sleep–wake cycle Brain Norepinephrine: Neurobiology and Therapeutics. 157-195. DOI: 10.1017/CBO9780511544156.007  1
2006 González MM, Aston-Jones G. Circadian regulation of arousal: role of the noradrenergic locus coeruleus system and light exposure. Sleep. 29: 1327-36. PMID 17068987  1
2006 Harris GC, Aston-Jones G. Arousal and reward: a dichotomy in orexin function. Trends in Neurosciences. 29: 571-7. PMID 16904760 DOI: 10.1016/j.tins.2006.08.002  1
2006 Georges F, Le Moine C, Aston-Jones G. No effect of morphine on ventral tegmental dopamine neurons during withdrawal. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5720-6. PMID 16723528 DOI: 10.1523/JNEUROSCI.5032-05.2006  1
2005 Aston-Jones G, Cohen JD. Adaptive gain and the role of the locus coeruleus-norepinephrine system in optimal performance. The Journal of Comparative Neurology. 493: 99-110. PMID 16254995 DOI: 10.1002/cne.20723  1
2005 Aston-Jones G. Brain structures and receptors involved in alertness. Sleep Medicine. 6: S3-7. PMID 16140243 DOI: 10.1016/S1389-9457(05)80002-4  1
2005 Harris GC, Wimmer M, Aston-Jones G. A role for lateral hypothalamic orexin neurons in reward seeking. Nature. 437: 556-9. PMID 16100511 DOI: 10.1038/nature04071  1
2005 Nieuwenhuis S, Aston-Jones G, Cohen JD. Decision making, the P3, and the locus coeruleus-norepinephrine system. Psychological Bulletin. 131: 510-32. PMID 16060800 DOI: 10.1037/0033-2909.131.4.510  1
2005 Cohen JD, Aston-Jones G. Cognitive neuroscience: decision amid uncertainty. Nature. 436: 471-2. PMID 16049461 DOI: 10.1038/436471a  1
2005 Aston-Jones G, Cohen JD. An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance. Annual Review of Neuroscience. 28: 403-50. PMID 16022602 DOI: 10.1146/annurev.neuro.28.061604.135709  1
2005 Holmes P, Shea-Brown E, Moehlis J, Bogacz R, Gao J, Aston-Jones G, Clayton E, Rajkowski J, Cohen JD. Optimal decisions: From neural spikes, through stochastic differential equations, to behavior Ieice Transactions On Fundamentals of Electronics, Communications and Computer Sciences. 2496-2502. DOI: 10.1093/ietfec/e88-a.10.2496  1
2005 Aston-Jones G, Card JP, Zhu Y, González M, Haggerty E. The Ne system as a target for hypocretin neurons implications for regulation of arousal Hypocretins: Integrators of Physiological Functions. 137-152. DOI: 10.1007/0-387-25446-3_9  1
2004 Harris GC, Wimmer M, Byrne R, Aston-Jones G. Glutamate-associated plasticity in the ventral tegmental area is necessary for conditioning environmental stimuli with morphine. Neuroscience. 129: 841-7. PMID 15541905 DOI: 10.1016/j.neuroscience.2004.09.018  1
2004 Clayton EC, Rajkowski J, Cohen JD, Aston-Jones G. Phasic activation of monkey locus ceruleus neurons by simple decisions in a forced-choice task. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9914-20. PMID 15525776 DOI: 10.1523/JNEUROSCI.2446-04.2004  1
2004 Aston-Jones G, Harris GC. Brain substrates for increased drug seeking during protracted withdrawal. Neuropharmacology. 47: 167-79. PMID 15464135 DOI: 10.1016/j.neuropharm.2004.06.020  1
2004 Brown E, Moehlis J, Holmes P, Clayton E, Rajkowski J, Aston-Jones G. The influence of spike rate and stimulus duration on noradrenergic neurons. Journal of Computational Neuroscience. 17: 13-29. PMID 15218351 DOI: 10.1023/B:JCNS.0000023867.25863.a4  1
2004 Rajkowski J, Majczynski H, Clayton E, Aston-Jones G. Activation of monkey locus coeruleus neurons varies with difficulty and performance in a target detection task. Journal of Neurophysiology. 92: 361-71. PMID 15028743 DOI: 10.1152/jn.00673.2003  1
2004 Aston-Jones G, Zhu Y, Card JP. Numerous GABAergic afferents to locus ceruleus in the pericerulear dendritic zone: possible interneuronal pool. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2313-21. PMID 14999082 DOI: 10.1523/JNEUROSCI.5339-03.2004  1
2004 Aston-Jones G. Locus Coeruleus, A5 and A7 Noradrenergic Cell Groups The Rat Nervous System. 259-294. DOI: 10.1016/B978-012547638-6/50012-2  0.52
2003 Harris GC, Aston-Jones G. Altered motivation and learning following opiate withdrawal: evidence for prolonged dysregulation of reward processing. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 865-71. PMID 12736632 DOI: 10.1038/sj.npp.1300122  1
2003 Georges F, Aston-Jones G. Prolonged activation of mesolimbic dopaminergic neurons by morphine withdrawal following clonidine: participation of imidazoline and norepinephrine receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1140-9. PMID 12700697 DOI: 10.1038/sj.npp.1300161  1
2003 Harris GC, Aston-Jones G. Enhanced morphine preference following prolonged abstinence: association with increased Fos expression in the extended amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 292-9. PMID 12589382 DOI: 10.1038/sj.npp.1300037  1
2003 Harris GC, Aston-Jones G. Critical role for ventral tegmental glutamate in preference for a cocaine-conditioned environment. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 73-6. PMID 12496942 DOI: 10.1038/sj.npp.1300011  1
2002 Gilzenrat MS, Holmes BD, Rajkowski J, Aston-Jones G, Cohen JD. Simplified dynamics in a model of noradrenergic modulation of cognitive performance. Neural Networks : the Official Journal of the International Neural Network Society. 15: 647-63. PMID 12371518 DOI: 10.1016/S0893-6080(02)00055-2  1
2002 Georges F, Aston-Jones G. Activation of ventral tegmental area cells by the bed nucleus of the stria terminalis: a novel excitatory amino acid input to midbrain dopamine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5173-87. PMID 12077212  1
2001 Georges F, Aston-Jones G. Potent regulation of midbrain dopamine neurons by the bed nucleus of the stria terminalis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: RC160. PMID 11473131  1
2001 Harris GC, Altomare K, Aston-Jones G. Preference for a cocaine-associated environment is attenuated by augmented accumbal serotonin in cocaine withdrawn rats. Psychopharmacology. 156: 14-22. PMID 11465629 DOI: 10.1007/s002130100693  1
2001 Aston-Jones G, Chen S, Zhu Y, Oshinsky ML. A neural circuit for circadian regulation of arousal. Nature Neuroscience. 4: 732-8. PMID 11426230 DOI: 10.1038/89522  1
2001 Ivanov A, Aston-Jones G. Local opiate withdrawal in locus coeruleus neurons in vitro. Journal of Neurophysiology. 85: 2388-97. PMID 11387385  1
2001 Harris GC, Aston-Jones G. Augmented accumbal serotonin levels decrease the preference for a morphine associated environment during withdrawal. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 75-85. PMID 11106878 DOI: 10.1016/S0893-133X(00)00184-6  1
2000 Aston-Jones G, Rajkowski J, Cohen J. Locus coeruleus and regulation of behavioral flexibility and attention. Progress in Brain Research. 126: 165-82. PMID 11105646 DOI: 10.1016/S0079-6123(00)26013-5  1
2000 Aston-Jones G, Card JP. Use of pseudorabies virus to delineate multisynaptic circuits in brain: opportunities and limitations. Journal of Neuroscience Methods. 103: 51-61. PMID 11074095 DOI: 10.1016/S0165-0270(00)00295-8  1
2000 Walters CL, Aston-Jones G, Druhan JP. Expression of fos-related antigens in the nucleus accumbens during opiate withdrawal and their attenuation by a D2 dopamine receptor agonist. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: 307-15. PMID 10942854 DOI: 10.1016/S0893-133X(00)00113-5  1
2000 Druhan JP, Walters CL, Aston-Jones G. Behavioral activation induced by D(2)-like receptor stimulation during opiate withdrawal. The Journal of Pharmacology and Experimental Therapeutics. 294: 531-8. PMID 10900229  1
2000 Ivanov A, Aston-Jones G. Hypocretin/orexin depolarizes and decreases potassium conductance in locus coeruleus neurons. Neuroreport. 11: 1755-8. PMID 10852238  1
2000 Delfs JM, Zhu Y, Druhan JP, Aston-Jones G. Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion. Nature. 403: 430-4. PMID 10667795 DOI: 10.1038/35000212  1
1999 Aston-Jones G, Rajkowski J, Cohen J. Role of locus coeruleus in attention and behavioral flexibility. Biological Psychiatry. 46: 1309-20. PMID 10560036 DOI: 10.1016/S0006-3223(99)00140-7  1
1999 Horvath TL, Peyron C, Diano S, Ivanov A, Aston-Jones G, Kilduff TS, van Den Pol AN. Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system. The Journal of Comparative Neurology. 415: 145-59. PMID 10545156 DOI: 10.1002/(SICI)1096-9861(19991213)415:2<145::AID-CNE1>3.0.CO;2-2  1
1999 Chen S, Yang M, Miselis RR, Aston-Jones G. Characterization of transsynaptic tracing with central application of pseudorabies virus. Brain Research. 838: 171-83. PMID 10446330 DOI: 10.1016/S0006-8993(99)01680-7  1
1999 Aston-Jones G, Druhan J. Behavioural pharmacology. Breaking the chain of addiction. Nature. 400: 317, 319. PMID 10432107 DOI: 10.1038/22432  1
1999 Aston-Jones G, Delfs JM, Druhan J, Zhu Y. The bed nucleus of the stria terminalis. A target site for noradrenergic actions in opiate withdrawal. Annals of the New York Academy of Sciences. 877: 486-98. PMID 10415666 DOI: 10.1111/j.1749-6632.1999.tb09284.x  1
1999 Aston-Jones G. The future of neurophysiology in neuropsychopharmacology. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 20: 509-12. PMID 10192832 DOI: 10.1016/S0893-133X(99)00013-5  1
1999 Usher M, Cohen JD, Servan-Schreiber D, Rajkowski J, Aston-Jones G. The role of locus coeruleus in the regulation of cognitive performance. Science (New York, N.Y.). 283: 549-54. PMID 9915705 DOI: 10.1126/science.283.5401.549  1
1998 Delfs JM, Zhu Y, Druhan JP, Aston-Jones GS. Origin of noradrenergic afferents to the shell subregion of the nucleus accumbens: anterograde and retrograde tract-tracing studies in the rat. Brain Research. 806: 127-40. PMID 9739125 DOI: 10.1016/S0006-8993(98)00672-6  1
1998 Rizvi TA, Murphy AZ, Ennis M, Aston-Jones G, Shipley MT. Fos expression in rat pontine tegmental neurons following activation of the medial preoptic area. Brain Research. 789: 256-62. PMID 9573379 DOI: 10.1016/S0006-8993(97)01548-5  1
1998 Chen S, Aston-Jones G. Axonal collateral-collateral transport of tract tracers in brain neurons: false anterograde labelling and useful tool. Neuroscience. 82: 1151-63. PMID 9466437 DOI: 10.1016/S0306-4522(97)00336-9  1
1998 Jodo E, Chiang C, Aston-Jones G. Potent excitatory influence of prefrontal cortex activity on noradrenergic locus coeruleus neurons. Neuroscience. 83: 63-79. PMID 9466399 DOI: 10.1016/S0306-4522(97)00372-2  1
1998 Kubiak P, Rajkowski J, Ivanova S, Aston-Jones G. Rapid acquisition of discriminative responding in monkey locus coeruleus neurons. Advances in Pharmacology (San Diego, Calif.). 42: 956-60. PMID 9328057 DOI: 10.1016/S1054-3589(08)60906-0  1
1998 Ennis M, Shipley MT, Aston-Jones G, Williams JT. Afferent control of nucleus locus ceruleus: differential regulation by "shell" and "core" inputs. Advances in Pharmacology (San Diego, Calif.). 42: 767-71. PMID 9328011 DOI: 10.1016/S1054-3589(08)60860-1  1
1998 Aston-Jones G, Rajkowski J, Ivanova S, Usher M, Cohen J. Neuromodulation and cognitive performance: recent studies of noradrenergic locus ceruleus neurons in behaving monkeys. Advances in Pharmacology (San Diego, Calif.). 42: 755-9. PMID 9328008 DOI: 10.1016/S1054-3589(08)60857-1  1
1998 Rajkowski J, Kubiak P, Ivanova S, Aston-Jones G. State-related activity, reactivity of locus ceruleus neurons in behaving monkeys. Advances in Pharmacology (San Diego, Calif.). 42: 740-4. PMID 9328005 DOI: 10.1016/S1054-3589(08)60854-6  1
1998 Grace AA, Gerfen CR, Aston-Jones G. Catecholamines in the central nervous system. Overview. Advances in Pharmacology (San Diego, Calif.). 42: 655-70. PMID 9327987 DOI: 10.1016/S1054-3589(08)60836-4  1
1997 Jodo E, Aston-Jones G. Activation of locus coeruleus by prefrontal cortex is mediated by excitatory amino acid inputs. Brain Research. 768: 327-32. PMID 9369332 DOI: 10.1016/S0006-8993(97)00703-8  1
1997 Aston-Jones G, Hirata H, Akaoka H. Local opiate withdrawal in locus coeruleus in vivo. Brain Research. 765: 331-6. PMID 9313908 DOI: 10.1016/S0006-8993(97)00682-3  1
1997 Aston-Jones G, Rajkowski J, Kubiak P. Conditioned responses of monkey locus coeruleus neurons anticipate acquisition of discriminative behavior in a vigilance task. Neuroscience. 80: 697-715. PMID 9276487 DOI: 10.1016/S0306-4522(97)00060-2  1
1996 Florin-Lechner SM, Druhan JP, Aston-Jones G, Valentino RJ. Enhanced norepinephrine release in prefrontal cortex with burst stimulation of the locus coeruleus. Brain Research. 742: 89-97. PMID 9117425 DOI: 10.1016/S0006-8993(96)00967-5  1
1996 Chen S, Aston-Jones G. Extensive projections from the midbrain periaqueductal gray to the caudal ventrolateral medulla: a retrograde and anterograde tracing study in the rat. Neuroscience. 71: 443-59. PMID 9053799 DOI: 10.1016/0306-4522(95)00437-8  1
1996 Valentino RJ, Chen S, Zhu Y, Aston-Jones G. Evidence for divergent projections to the brain noradrenergic system and the spinal parasympathetic system from Barrington's nucleus. Brain Research. 732: 1-15. PMID 8891263 DOI: 10.1016/0006-8993(96)00482-9  1
1996 Hirata H, Aston-Jones G. Long-latency responses of brain noradrenergic neurons to noxious stimuli are preferentially attenuated by intravenous morphine. Brain Research. 714: 9-18. PMID 8861604 DOI: 10.1016/0006-8993(95)01430-6  1
1996 Shipley MT, Fu L, Ennis M, Liu WL, Aston-Jones G. Dendrites of locus coeruleus neurons extend preferentially into two pericoerulear zones. The Journal of Comparative Neurology. 365: 56-68. PMID 8821441 DOI: 10.1002/(SICI)1096-9861(19960129)365:1<56::AID-CNE5>3.0.CO;2-I  1
1996 Aston-Jones G, Rajkowski J, Kubiak P, Valentino RJ, Shipley MT. Role of the locus coeruleus in emotional activation. Progress in Brain Research. 107: 379-402. PMID 8782532  1
1995 Ivanov A, Aston-Jones G. Extranuclear dendrites of locus coeruleus neurons: activation by glutamate and modulation of activity by alpha adrenoceptors. Journal of Neurophysiology. 74: 2427-36. PMID 8747203  1
1995 Chen S, Aston-Jones G. Evidence that cholera toxin B subunit (CTb) can be avidly taken up and transported by fibers of passage. Brain Research. 674: 107-11. PMID 7773677 DOI: 10.1016/0006-8993(95)00020-Q  1
1995 Luppi PH, Aston-Jones G, Akaoka H, Chouvet G, Jouvet M. Afferent projections to the rat locus coeruleus demonstrated by retrograde and anterograde tracing with cholera-toxin B subunit and Phaseolus vulgaris leucoagglutinin. Neuroscience. 65: 119-60. PMID 7753394 DOI: 10.1016/0306-4522(94)00481-J  1
1995 Van Bockstaele EJ, Aston-Jones G. Integration in the ventral medulla and coordination of sympathetic, pain and arousal functions. Clinical and Experimental Hypertension (New York, N.Y. : 1993). 17: 153-65. PMID 7735266 DOI: 10.3109/10641969509087062  1
1995 Chen S, Aston-Jones G. Anatomical evidence for inputs to ventrolateral medullary catecholaminergic neurons from the midbrain periaqueductal gray of the rat. Neuroscience Letters. 195: 140-4. PMID 7478270 DOI: 10.1016/0304-3940(94)11788-K  1
1994 Hirata H, Aston-Jones G. A novel long-latency response of locus coeruleus neurons to noxious stimuli: mediation by peripheral C-fibers. Journal of Neurophysiology. 71: 1752-61. PMID 8064346  1
1994 Aston-Jones G, Rajkowski J, Kubiak P, Alexinsky T. Locus coeruleus neurons in monkey are selectively activated by attended cues in a vigilance task. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 4467-80. PMID 8027789  1
1994 Chen S, Aston-Jones G. Cerebellar injury induces NADPH diaphorase in Purkinje and inferior olivary neurons in the rat. Experimental Neurology. 126: 270-6. PMID 7925824 DOI: 10.1006/exnr.1994.1064  1
1994 Harris GC, Aston-Jones G. Involvement of D2 dopamine receptors in the nucleus accumbens in the opiate withdrawal syndrome. Nature. 371: 155-7. PMID 7915401 DOI: 10.1038/371155a0  1
1994 Rajkowski J, Kubiak P, Aston-Jones G. Locus coeruleus activity in monkey: phasic and tonic changes are associated with altered vigilance. Brain Research Bulletin. 35: 607-16. PMID 7859118 DOI: 10.1016/0361-9230(94)90175-9  1
1994 Shiekhattar R, Aston-Jones G. Activation of adenylate cyclase attenuates the hyperpolarization following single action potentials in brain noradrenergic neurons independently of protein kinase A. Neuroscience. 62: 523-9. PMID 7830895 DOI: 10.1016/0306-4522(94)90385-9  1
1994 Valentino RJ, Page ME, Luppi PH, Zhu Y, Van Bockstaele E, Aston-Jones G. Evidence for widespread afferents to Barrington's nucleus, a brainstem region rich in corticotropin-releasing hormone neurons. Neuroscience. 62: 125-43. PMID 7816195 DOI: 10.1016/0306-4522(94)90320-4  1
1994 Rizvi TA, Ennis M, Aston-Jones G, Jiang M, Liu WL, Behbehani MM, Shipley MT. Preoptic projections to Barrington's nucleus and the pericoerulear region: architecture and terminal organization. The Journal of Comparative Neurology. 347: 1-24. PMID 7528227 DOI: 10.1002/cne.903470102  1
1993 Chiang C, Aston-Jones G. Response of locus coeruleus neurons to footshock stimulation is mediated by neurons in the rostral ventral medulla. Neuroscience. 53: 705-15. PMID 8487951 DOI: 10.1016/0306-4522(93)90618-P  1
1993 Grenhoff J, Nisell M, Ferré S, Aston-Jones G, Svensson TH. Noradrenergic modulation of midbrain dopamine cell firing elicited by stimulation of the locus coeruleus in the rat. Journal of Neural Transmission. General Section. 93: 11-25. PMID 8373553 DOI: 10.1007/BF01244934  1
1993 Akaoka H, Aston-Jones G. Indirect serotonergic agonists attenuate neuronal opiate withdrawal. Neuroscience. 54: 561-5. PMID 8332249 DOI: 10.1016/0306-4522(93)90227-7  1
1993 Shiekhattar R, Aston-Jones G. Modulation of opiate responses in brain noradrenergic neurons by the cyclic AMP cascade: changes with chronic morphine. Neuroscience. 57: 879-85. PMID 8309548 DOI: 10.1016/0306-4522(93)90032-B  1
1993 Shiekhattar R, Aston-Jones G. Sensory responsiveness of brain noradrenergic neurons is modulated by endogenous brain serotonin. Brain Research. 623: 72-6. PMID 8221096 DOI: 10.1016/0006-8993(93)90011-B  1
1993 Chiang C, Aston-Jones G. A 5-hydroxytryptamine2 agonist augments gamma-aminobutyric acid and excitatory amino acid inputs to noradrenergic locus coeruleus neurons. Neuroscience. 54: 409-20. PMID 8101639 DOI: 10.1016/0306-4522(93)90262-E  1
1993 Harris GC, Aston-Jones G. Beta-adrenergic antagonists attenuate somatic and aversive signs of opiate withdrawal. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 9: 303-11. PMID 7905738 DOI: 10.1038/npp.1993.66  1
1993 Charléty PJ, Chergui K, Akaoka H, Saunier CF, Buda M, Aston-Jones G, Chouvet G. Serotonin differentially modulates responses mediated by specific excitatory amino acid receptors in the rat locus coeruleus. The European Journal of Neuroscience. 5: 1024-8. PMID 7904220  1
1993 Harris GC, Aston-Jones G. Beta-adrenergic antagonists attenuate withdrawal anxiety in cocaine- and morphine-dependent rats. Psychopharmacology. 113: 131-6. PMID 7862819 DOI: 10.1007/BF02244345  1
1993 Van Bockstaele EJ, Akaoka H, Aston-Jones G. Brainstem afferents to the rostral (juxtafacial) nucleus paragigantocellularis: integration of exteroceptive and interoceptive sensory inputs in the ventral tegmentum. Brain Research. 603: 1-18. PMID 7680934 DOI: 10.1016/0006-8993(93)91293-2  1
1992 Shiekhattar R, Aston-Jones G. NMDA-receptor-mediated sensory responses of brain noradrenergic neurons are suppressed by in vivo concentrations of extracellular magnesium. Synapse (New York, N.Y.). 10: 103-9. PMID 1533954 DOI: 10.1002/syn.890100204  1
1992 Aston-Jones G, Rajkowski J, Kubiak P, Akaoka H. Acute morphine induces oscillatory discharge of noradrenergic locus coeruleus neurons in the waking monkey. Neuroscience Letters. 140: 219-24. PMID 1501782 DOI: 10.1016/0304-3940(92)90107-I  1
1992 Van Bockstaele EJ, Aston-Jones G. Distinct populations of neurons in the ventromedial periaqueductal gray project to the rostral ventral medulla and abducens nucleus. Brain Research. 576: 59-67. PMID 1381260 DOI: 10.1016/0006-8993(92)90609-D  1
1992 Van Bockstaele EJ, Aston-Jones G. Collateralized projections from neurons in the rostral medulla to the nucleus locus coeruleus, the nucleus of the solitary tract and the periaqueductal gray. Neuroscience. 49: 653-68. PMID 1380136 DOI: 10.1016/0306-4522(92)90234-S  1
1992 Drolet G, Van Bockstaele EJ, Aston-Jones G. Robust enkephalin innervation of the locus coeruleus from the rostral medulla. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 3162-74. PMID 1379635  1
1992 Valentino RJ, Page M, Van Bockstaele E, Aston-Jones G. Corticotropin-releasing factor innervation of the locus coeruleus region: distribution of fibers and sources of input. Neuroscience. 48: 689-705. PMID 1376457 DOI: 10.1016/0306-4522(92)90412-U  1
1992 Aston-Jones G, Astier B, Ennis M. Inhibition of noradrenergic locus coeruleus neurons by C1 adrenergic cells in the rostral ventral medulla. Neuroscience. 48: 371-81. PMID 1351268 DOI: 10.1016/0306-4522(92)90497-P  1
1992 Shiekhattar R, Aston-Jones G. Local application of bicuculline potentiates NMDA-receptor-mediated sensory responses of brain noradrenergic neurons. Synapse (New York, N.Y.). 10: 54-61. PMID 1346944 DOI: 10.1002/syn.890100108  1
1992 Page ME, Akaoka H, Aston-Jones G, Valentino RJ. Bladder distention activates noradrenergic locus coeruleus neurons by an excitatory amino acid mechanism. Neuroscience. 51: 555-63. PMID 1336819 DOI: 10.1016/0306-4522(92)90295-D  1
1992 Ennis M, Aston-Jones G, Shiekhattar R. Activation of locus coeruleus neurons by nucleus paragigantocellularis or noxious sensory stimulation is mediated by intracoerulear excitatory amino acid neurotransmission. Brain Research. 598: 185-95. PMID 1336704 DOI: 10.1016/0006-8993(92)90182-9  1
1991 Shiekhattar R, Aston-Jones G, Chiang C. Local infusion of calcium-free solutions in vivo activates locus coeruleus neurons. Brain Research Bulletin. 27: 5-12. PMID 1933435 DOI: 10.1016/0361-9230(91)90273-M  1
1991 Charlety PJ, Aston-Jones G, Akaoka H, Buda M, Chouvet G. [Participation of 5-HT 1A receptors in the decrease by serotonin of activation of locus coeruleus neurons by glutamate]. Comptes Rendus De L'AcadéMie Des Sciences. SéRie Iii, Sciences De La Vie. 312: 421-6. PMID 1905186  1
1991 Aston-Jones G, Chiang C, Alexinsky T. Discharge of noradrenergic locus coeruleus neurons in behaving rats and monkeys suggests a role in vigilance. Progress in Brain Research. 88: 501-20. PMID 1813931  1
1991 Van Bockstaele EJ, Aston-Jones G, Pieribone VA, Ennis M, Shipley MT. Subregions of the periaqueductal gray topographically innervate the rostral ventral medulla in the rat. The Journal of Comparative Neurology. 309: 305-27. PMID 1717516 DOI: 10.1002/cne.903090303  1
1991 Pieribone VA, Aston-Jones G. Adrenergic innervation of the rat nucleus locus coeruleus arises predominantly from the C1 adrenergic cell group in the rostral medulla. Neuroscience. 41: 525-42. PMID 1714551 DOI: 10.1016/0306-4522(91)90346-P  1
1991 Ennis M, Behbehani M, Shipley MT, Van Bockstaele EJ, Aston-Jones G. Projections from the periaqueductal gray to the rostromedial pericoerulear region and nucleus locus coeruleus: anatomic and physiologic studies. The Journal of Comparative Neurology. 306: 480-94. PMID 1713927 DOI: 10.1002/cne.903060311  1
1991 Aston-Jones G, Shipley MT, Chouvet G, Ennis M, van Bockstaele E, Pieribone V, Shiekhattar R, Akaoka H, Drolet G, Astier B. Afferent regulation of locus coeruleus neurons: anatomy, physiology and pharmacology. Progress in Brain Research. 88: 47-75. PMID 1687622  1
1991 Akaoka H, Aston-Jones G. Opiate withdrawal-induced hyperactivity of locus coeruleus neurons is substantially mediated by augmented excitatory amino acid input. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 3830-9. PMID 1683899  1
1991 Aston-Jones G, Akaoka H, Charléty P, Chouvet G. Serotonin selectively attenuates glutamate-evoked activation of noradrenergic locus coeruleus neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 760-9. PMID 1672153  1
1990 Astier B, Van Bockstaele EJ, Aston-Jones G, Pieribone VA. Anatomical evidence for multiple pathways leading from the rostral ventrolateral medulla (nucleus paragigantocellularis) to the locus coeruleus in rat. Neuroscience Letters. 118: 141-6. PMID 2274260 DOI: 10.1016/0304-3940(90)90612-D  1
1990 Buzsáki G, Smith A, Berger S, Fisher LJ, Gage FH. Petit mal epilepsy and parkinsonian tremor: hypothesis of a common pacemaker. Neuroscience. 36: 1-14. PMID 2120612 DOI: 10.1016/0306-4522(90)90345-5  1
1989 Ennis M, Aston-Jones G. GABA-mediated inhibition of locus coeruleus from the dorsomedial rostral medulla. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 2973-81. PMID 2769374  1
1989 McLean JH, Shipley MT, Nickell WT, Aston-Jones G, Reyher CK. Chemoanatomical organization of the noradrenergic input from locus coeruleus to the olfactory bulb of the adult rat. The Journal of Comparative Neurology. 285: 339-49. PMID 2547851 DOI: 10.1002/cne.902850305  1
1989 Van Bockstaele EJ, Pieribone VA, Aston-Jones G. Diverse afferents converge on the nucleus paragigantocellularis in the rat ventrolateral medulla: retrograde and anterograde tracing studies. The Journal of Comparative Neurology. 290: 561-84. PMID 2482306 DOI: 10.1002/cne.902900410  1
1989 Ennis M, Aston-Jones G. Potent inhibitory input to locus coeruleus from the nucleus prepositus hypoglossi. Brain Research Bulletin. 22: 793-803. PMID 2475220 DOI: 10.1016/0361-9230(89)90022-1  1
1988 Pieribone VA, Aston-Jones G, Bohn MC. Adrenergic and non-adrenergic neurons in the C1 and C3 areas project to locus coeruleus: a fluorescent double labeling study. Neuroscience Letters. 85: 297-303. PMID 3362420 DOI: 10.1016/0304-3940(88)90582-4  1
1988 Pieribone VA, Aston-Jones G. The iontophoretic application of Fluoro-Gold for the study of afferents to deep brain nuclei. Brain Research. 475: 259-71. PMID 3214735 DOI: 10.1016/0006-8993(88)90614-2  1
1988 Rogers J, Aston-Jones G. The neurophysiology of aging: insights from new applications of old techniques. Neurobiology of Aging. 9: 601-5. PMID 3211263 DOI: 10.1016/S0197-4580(88)80119-2  1
1988 Ennis M, Aston-Jones G. Activation of locus coeruleus from nucleus paragigantocellularis: a new excitatory amino acid pathway in brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 3644-57. PMID 3193175  1
1988 Grant SJ, Aston-Jones G, Redmond DE. Responses of primate locus coeruleus neurons to simple and complex sensory stimuli. Brain Research Bulletin. 21: 401-10. PMID 3145784 DOI: 10.1016/0361-9230(88)90152-9  1
1988 Chouvet G, Akaoka H, Aston-Jones G. [Selective reduction by serotonin, of neuronal excitation in the locus coeruleus evoked by glutamate]. Comptes Rendus De L'AcadéMie Des Sciences. SéRie Iii, Sciences De La Vie. 306: 339-44. PMID 2897873  1
1987 Ennis M, Aston-Jones G. Two physiologically distinct populations of neurons in the ventrolateral medulla innervate the locus coeruleus. Brain Research. 425: 275-82. PMID 3427430 DOI: 10.1016/0006-8993(87)90510-5  1
1987 Mesulam MM. Asymmetry of neural feedback in the organization of behavioral states. Science (New York, N.Y.). 237: 537-8. PMID 3110953  1
1986 Grenhoff J, Aston-Jones G, Svensson TH. Nicotinic effects on the firing pattern of midbrain dopamine neurons. Acta Physiologica Scandinavica. 128: 351-8. PMID 3788613 DOI: 10.1111/j.1748-1716.1986.tb07988.x  1
1986 Aston-Jones G, Ennis M, Pieribone VA, Nickell WT, Shipley MT. The brain nucleus locus coeruleus: restricted afferent control of a broad efferent network. Science (New York, N.Y.). 234: 734-7. PMID 3775363  1
1986 Ennis M, Aston-Jones G. Evidence for self- and neighbor-mediated postactivation inhibition of locus coeruleus neurons. Brain Research. 374: 299-305. PMID 3719339 DOI: 10.1016/0006-8993(86)90424-5  1
1986 Ennis M, Aston-Jones G. A potent excitatory input to the nucleus locus coeruleus from the ventrolateral medulla. Neuroscience Letters. 71: 299-305. PMID 3025783 DOI: 10.1016/0304-3940(86)90637-3  1
1985 Aston-Jones G, Foote SL, Segal M. Impulse conduction properties of noradrenergic locus coeruleus axons projecting to monkey cerebrocortex. Neuroscience. 15: 765-77. PMID 4069354 DOI: 10.1016/0306-4522(85)90077-6  1
1985 Aston-Jones G, Rogers J, Shaver RD, Dinan TG, Moss DE. Age-impaired impulse flow from nucleus basalis to cortex. Nature. 318: 462-4. PMID 4069217 DOI: 10.1038/318462a0  1
1985 Dinan TG, Aston-Jones G. Chronic haloperidol inactivates brain noradrenergic neurons. Brain Research. 325: 385-8. PMID 3978430 DOI: 10.1016/0006-8993(85)90346-4  1
1985 Aston-Jones G, Shaver R, Dinan TG. Nucleus basalis neurons exhibit axonal branching with decreased impulse conduction velocity in rat cerebrocortex. Brain Research. 325: 271-85. PMID 3978419 DOI: 10.1016/0006-8993(85)90323-3  1
1985 Aston-Jones G. Behavioral functions of locus coeruleus derived from cellular attributes Physiological Psychology. 13: 118-126. DOI: 10.3758/BF03326513  1
1984 Aston-Jones S, Aston-Jones G, Koob GF. Cocaine antagonizes anxiolytic effects of ethanol. Psychopharmacology. 84: 28-31. PMID 6149593 DOI: 10.1007/BF00432019  1
1983 Valentino RJ, Aston-Jones G. Activation of locus coeruleus neurons in the rat by a benzazocine derivative (UM 1046) that mimics opiate withdrawal. Neuropharmacology. 22: 1363-8. PMID 6686652 DOI: 10.1016/0028-3908(83)90225-3  1
1983 Segal M, Foote SL, Aston-Jones G. Physiological properties of ascending locus coeruleus axons in the squirrel monkey. Brain Research. 274: 381-7. PMID 6626968 DOI: 10.1016/0006-8993(83)90723-0  1
1983 Valentino RJ, Foote SL, Aston-Jones G. Corticotropin-releasing factor activates noradrenergic neurons of the locus coeruleus. Brain Research. 270: 363-7. PMID 6603889 DOI: 10.1016/0006-8993(83)90615-7  1
1983 Foote SL, Bloom FE, Aston-Jones G. Nucleus locus ceruleus: new evidence of anatomical and physiological specificity. Physiological Reviews. 63: 844-914. PMID 6308694  1
1982 Aston-Jones G, Foote SL, Bloom FE. Low doses of ethanol disrupt sensory responses of brain noradrenergic neurones. Nature. 296: 857-60. PMID 6280069  1
1981 Aston-Jones G, Bloom FE. Norepinephrine-containing locus coeruleus neurons in behaving rats exhibit pronounced responses to non-noxious environmental stimuli. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 1: 887-900. PMID 7346593  1
1981 Aston-Jones G, Bloom FE. Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 1: 876-86. PMID 7346592  1
1980 Aston-Jones G, Segal M, Bloom FE. Brain aminergic axons exhibit marked variability in conduction velocity. Brain Research. 195: 215-22. PMID 7397496  1
1980 Foote SL, Aston-Jones G, Bloom FE. Impulse activity of locus coeruleus neurons in awake rats and monkeys is a function of sensory stimulation and arousal. Proceedings of the National Academy of Sciences of the United States of America. 77: 3033-7. PMID 6771765  1
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