| Year |
Citation |
Score |
| 2023 |
Fernandes I, Funakoshi S, Hamidzada H, Epelman S, Keller G. Modeling cardiac fibroblast heterogeneity from human pluripotent stem cell-derived epicardial cells. Nature Communications. 14: 8183. PMID 38081833 DOI: 10.1038/s41467-023-43312-0 |
0.464 |
|
| 2023 |
Wauchop M, Rafatian N, Zhao Y, Chen W, Gagliardi M, Massé S, Cox BJ, Lai P, Liang T, Landau S, Protze S, Gao XD, Wang EY, Tung KC, Laksman Z, ... ... Keller G, et al. Maturation of iPSC-derived cardiomyocytes in a heart-on-a-chip device enables modeling of dilated cardiomyopathy caused by R222Q-SCN5A mutation. Biomaterials. 301: 122255. PMID 37651922 DOI: 10.1016/j.biomaterials.2023.122255 |
0.353 |
|
| 2022 |
Yang D, Gomez-Garcia J, Funakoshi S, Tran T, Fernandes I, Bader GD, Laflamme MA, Keller GM. Modeling human multi-lineage heart field development with pluripotent stem cells. Cell Stem Cell. 29: 1382-1401.e8. PMID 36055193 DOI: 10.1016/j.stem.2022.08.007 |
0.399 |
|
| 2022 |
Gage BK, Merlin S, Olgasi C, Follenzi A, Keller GM. Therapeutic correction of hemophilia A by transplantation of hPSC-derived liver sinusoidal endothelial cell progenitors. Cell Reports. 39: 110621. PMID 35385743 DOI: 10.1016/j.celrep.2022.110621 |
0.381 |
|
| 2022 |
Dhahri W, Sadikov Valdman T, Wilkinson D, Pereira E, Ceylan E, Andharia N, Qiang B, Masoudpour H, Wulkan F, Quesnel E, Jiang W, Funakoshi S, Mazine A, Gomez-Garcia MJ, Latifi N, ... ... Keller G, et al. In Vitro Matured Human Pluripotent Stem Cell-derived Cardiomyocytes Form Grafts With Enhanced Structure and Function in Injured Hearts. Circulation. PMID 35089805 DOI: 10.1161/CIRCULATIONAHA.121.053563 |
0.473 |
|
| 2021 |
Atkins MH, Scarfò R, McGrath KE, Yang D, Palis J, Ditadi A, Keller GM. Modeling human yolk sac hematopoiesis with pluripotent stem cells. The Journal of Experimental Medicine. 219. PMID 34928315 DOI: 10.1084/jem.20211924 |
0.507 |
|
| 2021 |
Funakoshi S, Fernandes I, Mastikhina O, Wilkinson D, Tran T, Dhahri W, Mazine A, Yang D, Burnett B, Lee J, Protze S, Bader GD, Nunes SS, Laflamme M, Keller G. Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells. Nature Communications. 12: 3155. PMID 34039977 DOI: 10.1038/s41467-021-23329-z |
0.452 |
|
| 2021 |
Williams K, Liang T, Massé S, Khan S, Hatkar R, Keller G, Nanthakumar K, Nunes SS. A 3-D Human Model of Complex Cardiac Arrhythmias. Acta Biomaterialia. PMID 33713861 DOI: 10.1016/j.actbio.2021.03.004 |
0.376 |
|
| 2021 |
Williams K, Liang T, Massé S, Khan S, Hatkar R, Keller G, Nanthakumar K, Nunes SS. A 3-D Human Model of Complex Cardiac Arrhythmias. Acta Biomaterialia. PMID 33713861 DOI: 10.1016/j.actbio.2021.03.004 |
0.376 |
|
| 2020 |
Mikryukov AA, Mazine A, Wei B, Yang D, Miao Y, Gu M, Keller GM. BMP10 Signaling Promotes the Development of Endocardial Cells from Human Pluripotent Stem Cell-Derived Cardiovascular Progenitors. Cell Stem Cell. PMID 33142114 DOI: 10.1016/j.stem.2020.10.003 |
0.541 |
|
| 2020 |
Sun X, Wu J, Qiang B, Romagnuolo R, Gagliardi M, Keller G, Laflamme MA, Li RK, Nunes SS. Transplanted microvessels improve pluripotent stem cell-derived cardiomyocyte engraftment and cardiac function after infarction in rats. Science Translational Medicine. 12. PMID 32967972 DOI: 10.1126/scitranslmed.aax2992 |
0.378 |
|
| 2020 |
Ballan N, Shaheen N, Keller GM, Gepstein L. Single-Cell Mechanical Analysis of Human Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Testing and Pathophysiological Studies. Stem Cell Reports. PMID 32763158 DOI: 10.1016/j.stemcr.2020.07.006 |
0.377 |
|
| 2020 |
Gage BK, Liu JC, Innes BT, MacParland SA, McGilvray ID, Bader GD, Keller GM. Generation of Functional Liver Sinusoidal Endothelial Cells from Human Pluripotent Stem-Cell-Derived Venous Angioblasts. Cell Stem Cell. PMID 32640183 DOI: 10.1016/J.Stem.2020.06.007 |
0.355 |
|
| 2020 |
Wang Z, Gagliardi M, Mohamadi RM, Ahmed SU, Labib M, Zhang L, Popescu S, Zhou Y, Sargent EH, Keller GM, Kelley SO. Ultrasensitive and rapid quantification of rare tumorigenic stem cells in hPSC-derived cardiomyocyte populations. Science Advances. 6: eaay7629. PMID 32440533 DOI: 10.1126/Sciadv.Aay7629 |
0.441 |
|
| 2020 |
Thavandiran N, Hale C, Blit P, Sandberg ML, McElvain ME, Gagliardi M, Sun B, Witty A, Graham G, Do VTH, Bakooshli MA, Le H, Ostblom J, McEwen S, Chau E, ... ... Keller G, et al. Functional arrays of human pluripotent stem cell-derived cardiac microtissues. Scientific Reports. 10: 6919. PMID 32332814 DOI: 10.1038/S41598-020-62955-3 |
0.433 |
|
| 2020 |
Siraj MA, Mundil D, Beca S, Momen A, Shikatani EA, Afroze T, Sun X, Liu Y, Ghaffari S, Lee W, Wheeler MB, Keller G, Backx P, Husain M. Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-α. The Journal of Clinical Investigation. PMID 31985487 DOI: 10.1172/Jci99934 |
0.335 |
|
| 2020 |
Goldfracht I, Protze S, Shiti A, Setter N, Gruber A, Shaheen N, Nartiss Y, Keller G, Gepstein L. Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes. Nature Communications. 11: 75. PMID 31911598 DOI: 10.1038/S41467-019-13868-X |
0.514 |
|
| 2019 |
Protze SI, Lee JH, Keller GM. Human Pluripotent Stem Cell-Derived Cardiovascular Cells: From Developmental Biology to Therapeutic Applications. Cell Stem Cell. 25: 311-327. PMID 31491395 DOI: 10.1016/j.stem.2019.07.010 |
0.469 |
|
| 2019 |
Romagnuolo R, Masoudpour H, Porta-Sánchez A, Qiang B, Barry J, Laskary A, Qi X, Massé S, Magtibay K, Kawajiri H, Wu J, Valdman Sadikov T, Rothberg J, Panchalingam KM, Titus E, ... ... Keller G, et al. Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate the Infarcted Pig Heart but Induce Ventricular Tachyarrhythmias. Stem Cell Reports. PMID 31056479 DOI: 10.1016/J.Stemcr.2019.04.005 |
0.352 |
|
| 2019 |
Shafaattalab S, Lin E, Christidi E, Huang H, Nartiss Y, Garcia A, Lee J, Protze S, Keller G, Brunham L, Tibbits GF, Laksman Z. Ibrutinib Displays Atrial-Specific Toxicity in Human Stem Cell-Derived Cardiomyocytes. Stem Cell Reports. PMID 31031187 DOI: 10.1016/j.stemcr.2019.03.011 |
0.375 |
|
| 2019 |
Mair B, Tomic J, Masud SN, Tonge P, Weiss A, Usaj M, Tong AHY, Kwan JJ, Brown KR, Titus E, Atkins M, Chan KSK, Munsie L, Habsid A, Han H, ... ... Keller G, et al. Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies. Cell Reports. 27: 599-615.e12. PMID 30970261 DOI: 10.1016/J.Celrep.2019.02.041 |
0.426 |
|
| 2019 |
Zhao Y, Rafatian N, Feric NT, Cox BJ, Aschar-Sobbi R, Wang EY, Aggarwal P, Zhang B, Conant G, Ronaldson-Bouchard K, Pahnke A, Protze S, Lee JH, Davenport Huyer L, Jekic D, ... ... Keller GM, et al. A Platform for Generation of Chamber-Specific Cardiac Tissues and Disease Modeling. Cell. PMID 30686581 DOI: 10.1016/J.Cell.2018.11.042 |
0.325 |
|
| 2018 |
Keller G. Translating human development to new therapies with pluripotent stem cells Experimental Hematology. 64. DOI: 10.1016/J.Exphem.2018.06.038 |
0.515 |
|
| 2018 |
Romagnuolo R, Masoudpoor H, Porta-Sanchez A, Qiang B, Barry J, Qi X, Masse S, Magtibay K, Laskary A, Wu J, Valdman-Sadikov T, Rothberg J, Titus E, Li R, Zandstra P, ... ... Keller G, et al. REGENERATING THE INFARCTED PIG HEART WITH HUMAN EMBRYONIC STEM CELL-DERIVED CARDIOMYOCYTES INDUCES VENTRICULAR TACHYARRHYTHMIAS Canadian Journal of Cardiology. 34: S140-S141. DOI: 10.1016/J.Cjca.2018.07.196 |
0.546 |
|
| 2018 |
Porta-Sanchez A, Nayyar S, Magtibay K, Masse S, Bhaskaran A, Romagnuolo R, Masoudpoor H, Qiang B, Biswas L, Ghugre N, Keller G, LaFlamme M, Nanthakumar K. CARDIAC REGENERATION WITH HUMAN EMBRYONIC STEM CELL-DERIVED CARDIOMYOCYTES IN INFARCTED SWINE IS ASSOCIATED WITH VENTRICULAR TACHYCARDIA THAT HAS FOCAL PATTERN OF ACTIVATION Canadian Journal of Cardiology. 34: S187-S188. DOI: 10.1016/J.Cjca.2018.07.128 |
0.525 |
|
| 2017 |
Nunes SS, Feric N, Pahnke A, Miklas JW, Li M, Coles J, Gagliardi M, Keller G, Radisic M. Human Stem Cell-Derived Cardiac Model of Chronic Drug Exposure. Acs Biomaterials Science & Engineering. 3: 1911-1921. PMID 33440549 DOI: 10.1021/acsbiomaterials.5b00496 |
0.358 |
|
| 2017 |
Yoon C, Song H, Yin T, Bausch-Fluck D, Frei AP, Kattman S, Dubois N, Witty AD, Hewel JA, Guo H, Emili A, Wollscheid B, Keller G, Zandstra PW. FZD4 Marks Lateral Plate Mesoderm and Signals with NORRIN to Increase Cardiomyocyte Induction from Pluripotent Stem Cell-Derived Cardiac Progenitors. Stem Cell Reports. PMID 29249665 DOI: 10.1016/J.Stemcr.2017.11.008 |
0.803 |
|
| 2017 |
Yoon C, Song H, Yin T, Bausch-Fluck D, Frei AP, Kattman S, Dubois N, Witty AD, Hewel JA, Guo H, Emili A, Wollscheid B, Keller G, Zandstra PW. FZD4 Marks Lateral Plate Mesoderm and Signals with NORRIN to Increase Cardiomyocyte Induction from Pluripotent Stem Cell-Derived Cardiac Progenitors. Stem Cell Reports. PMID 29249665 DOI: 10.1016/J.Stemcr.2017.11.008 |
0.803 |
|
| 2017 |
Martewicz S, Serena E, Zatti S, Keller G, Elvassore N. Substrate and mechanotransduction influence SERCA2a localization in human pluripotent stem cell-derived cardiomyocytes affecting functional performance. Stem Cell Research. 25: 107-114. PMID 29125993 DOI: 10.1016/J.Scr.2017.10.011 |
0.482 |
|
| 2017 |
Lee JH, Protze SI, Laksman Z, Backx PH, Keller GM. Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations. Cell Stem Cell. 21: 179-194.e4. PMID 28777944 DOI: 10.1016/j.stem.2017.07.003 |
0.467 |
|
| 2017 |
Laksman Z, Wauchop M, Lin E, Protze S, Lee J, Yang W, Izaddoustdar F, Shafaattalab S, Gepstein L, Tibbits GF, Keller G, Backx PH. Modeling Atrial Fibrillation using Human Embryonic Stem Cell-Derived Atrial Tissue. Scientific Reports. 7: 5268. PMID 28706272 DOI: 10.1038/S41598-017-05652-Y |
0.402 |
|
| 2017 |
Sugimura R, Jha DK, Han A, Soria-Valles C, da Rocha EL, Lu YF, Goettel JA, Serrao E, Rowe RG, Malleshaiah M, Wong I, Sousa P, Zhu TN, Ditadi A, Keller G, et al. Haematopoietic stem and progenitor cells from human pluripotent stem cells. Nature. 545: 432-438. PMID 28514439 DOI: 10.1038/Nature22370 |
0.603 |
|
| 2017 |
Tiburcy M, Hudson JE, Balfanz P, Schlick SF, Meyer T, Chang Liao ML, Levent E, Raad F, Zeidler S, Wingender E, Riegler J, Wang M, Gold JD, Kehat I, Wettwer E, ... ... Keller G, et al. Defined Engineered Human Myocardium with Advanced Maturation for Applications in Heart Failure Modelling and Repair. Circulation. PMID 28167635 DOI: 10.1161/Circulationaha.116.024145 |
0.432 |
|
| 2017 |
Dekker B, Sugimura R, Jha DK, Han A, Soria-Valles C, Rocha ELd, Lu Y, Goettel JA, Serrao E, Rowe RG, Malleshaiah M, Wong I, Sousa P, Zhu TN, Ditadi A, ... Keller G, et al. Hematopoietic stem/progenitor cell conversion from human pluripotent stem cells Protocol Exchange. DOI: 10.1038/Protex.2017.045 |
0.576 |
|
| 2016 |
Protze SI, Liu J, Nussinovitch U, Ohana L, Backx PH, Gepstein L, Keller GM. Sinoatrial node cardiomyocytes derived from human pluripotent cells function as a biological pacemaker. Nature Biotechnology. PMID 27941801 DOI: 10.1038/nbt.3745 |
0.4 |
|
| 2016 |
Ditadi A, Sturgeon CM, Keller G. A view of human haematopoietic development from the Petri dish. Nature Reviews. Molecular Cell Biology. PMID 27876786 DOI: 10.1038/Nrm.2016.127 |
0.558 |
|
| 2016 |
Brauer PM, Pessach IM, Clarke E, Rowe JH, Ott de Bruin L, Lee YN, Dominguez-Brauer C, Comeau AM, Awong G, Felgentreff K, Zhang YH, Bredemeyer A, Al-Herz W, Du L, Ververs F, ... ... Keller G, et al. Modeling altered T-cell development with human induced pluripotent stem cells from patients with RAG1 mutations and distinct immunological phenotypes. Blood. PMID 27301863 DOI: 10.1182/Blood-2015-10-676304 |
0.347 |
|
| 2016 |
Zhang B, Montgomery M, Chamberlain MD, Ogawa S, Korolj A, Pahnke A, Wells LA, Massé S, Kim J, Reis L, Momen A, Nunes SS, Wheeler AR, Nanthakumar K, Keller G, et al. Biodegradable scaffold with built-in vasculature for organ-on-a-chip engineering and direct surgical anastomosis. Nature Materials. PMID 26950595 DOI: 10.1038/Nmat4570 |
0.34 |
|
| 2016 |
Eng G, Lee BW, Protas L, Gagliardi M, Brown K, Kass RS, Keller G, Robinson RB, Vunjak-Novakovic G. Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes. Nature Communications. 7: 10312. PMID 26785135 DOI: 10.1038/Ncomms10312 |
0.587 |
|
| 2016 |
Sugimura R, Han A, Jha D, Lu Y, Goettel JA, Serrao E, Rowe RG, Wong I, Sousa P, Ditadi A, Keller G, Engelman A, Snapper S, Doulatov S, Daley GQ. Hematopoietic Stem and Progenitor Cells from Human Pluripotent Stem Cells Via Transcription Factor Conversion of Hemogenic Endothelium Blood. 128: 371-371. DOI: 10.1182/Blood.V128.22.371.371 |
0.57 |
|
| 2016 |
Huang L, Holtzinger A, Jagan I, Nostro C, Wang R, Muthuswamy L, Arrowsmith C, Cleary S, Schaeffer D, Roehrl M, Ming-Sound T, Gallinger S, Keller G, Muthuswamy S. Abstract B45: Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell and patient-derived tumor organoids Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-B45 |
0.432 |
|
| 2016 |
Nunes SS, Feric N, Pahnke A, Miklas JW, Li M, Coles J, Gagliardi M, Keller G, Radisic M. Human Stem Cell-Derived Cardiac Model of Chronic Drug Exposure Acs Biomaterials Science & Engineering. 3: 1911-1921. DOI: 10.1021/Acsbiomaterials.5B00496 |
0.454 |
|
| 2016 |
Keller G. Modeling human hematopoietic development with pluripotent stem cells Experimental Hematology. 44. DOI: 10.1016/J.Exphem.2016.06.037 |
0.558 |
|
| 2015 |
Fernandes S, Chong JJ, Paige SL, Iwata M, Torok-Storb B, Keller G, Reinecke H, Murry CE. Comparison of Human Embryonic Stem Cell-Derived Cardiomyocytes, Cardiovascular Progenitors, and Bone Marrow Mononuclear Cells for Cardiac Repair. Stem Cell Reports. PMID 26607951 DOI: 10.1016/J.Stemcr.2015.09.011 |
0.545 |
|
| 2015 |
Huang L, Holtzinger A, Jagan I, BeGora M, Lohse I, Ngai N, Nostro C, Wang R, Muthuswamy LB, Crawford HC, Arrowsmith C, Kalloger SE, Renouf DJ, Connor AA, Cleary S, ... ... Keller G, et al. Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids. Nature Medicine. PMID 26501191 DOI: 10.1038/Nm.3973 |
0.425 |
|
| 2015 |
Holtzinger A, Streeter PR, Sarangi F, Hillborn S, Niapour M, Ogawa S, Keller G. New markers for tracking endoderm induction and hepatocyte differentiation from human pluripotent stem cells. Development (Cambridge, England). PMID 26493401 DOI: 10.1242/Dev.121020 |
0.547 |
|
| 2015 |
Li LB, Ma C, Awong G, Kennedy M, Gornalusse G, Keller G, Kaufman DS, Russell DW. Silent IL2RG Gene Editing in Human Pluripotent Stem Cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26444081 DOI: 10.1038/Mt.2015.190 |
0.477 |
|
| 2015 |
Sharma P, Abbasi C, Lazic S, Teng AC, Wang D, Dubois N, Ignatchenko V, Wong V, Liu J, Araki T, Tiburcy M, Ackerley C, Zimmermann WH, Hamilton R, Sun Y, ... ... Keller G, et al. Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function. Nature Communications. 6: 8391. PMID 26403541 DOI: 10.1038/Ncomms9391 |
0.698 |
|
| 2015 |
Clarke RL, Robitaille AM, Moon RT, Keller G. A Quantitative Proteomic Analysis of Hemogenic Endothelium Reveals Differential Regulation of Hematopoiesis by SOX17. Stem Cell Reports. 5: 291-304. PMID 26267830 DOI: 10.1016/J.Stemcr.2015.07.008 |
0.553 |
|
| 2015 |
Ogawa M, Ogawa S, Bear CE, Ahmadi S, Chin S, Li B, Grompe M, Keller G, Kamath BM, Ghanekar A. Directed differentiation of cholangiocytes from human pluripotent stem cells. Nature Biotechnology. 33: 853-61. PMID 26167630 DOI: 10.1038/Nbt.3294 |
0.51 |
|
| 2015 |
Craft AM, Rockel JS, Nartiss Y, Kandel RA, Alman BA, Keller GM. Generation of articular chondrocytes from human pluripotent stem cells. Nature Biotechnology. 33: 638-45. PMID 25961409 DOI: 10.1038/Nbt.3210 |
0.424 |
|
| 2015 |
Amer LD, Holtzinger A, Keller G, Mahoney MJ, Bryant SJ. Enzymatically degradable poly(ethylene glycol) hydrogels for the 3D culture and release of human embryonic stem cell derived pancreatic precursor cell aggregates. Acta Biomaterialia. 22: 103-10. PMID 25913222 DOI: 10.1016/J.Actbio.2015.04.013 |
0.425 |
|
| 2015 |
Ruan JL, Tulloch NL, Saiget M, Paige SL, Razumova MV, Regnier M, Tung KC, Keller G, Pabon L, Reinecke H, Murry CE. Mechanical Stress Promotes Maturation of Human Myocardium From Pluripotent Stem Cell-Derived Progenitors. Stem Cells (Dayton, Ohio). 33: 2148-57. PMID 25865043 DOI: 10.1002/Stem.2036 |
0.508 |
|
| 2015 |
Nostro MC, Sarangi F, Yang C, Holland A, Elefanty AG, Stanley EG, Greiner DL, Keller G. Efficient generation of NKX6-1+ pancreatic progenitors from multiple human pluripotent stem cell lines. Stem Cell Reports. 4: 591-604. PMID 25843049 DOI: 10.1016/J.Stemcr.2015.02.017 |
0.554 |
|
| 2015 |
Pourquié O, Bruneau B, Keller G, Smith A. Looking inwards: opening a window onto human development. Development (Cambridge, England). 142: 1-2. PMID 25516961 DOI: 10.1242/Dev.119727 |
0.34 |
|
| 2015 |
Thavandiran N, Dubois N, Mikryukov A, Massé S, Beca B, Simmons CA, Deshpande VS, McGarry JP, Chen CS, Nanthakumar K, Keller GM, Radisic M, Zandstra PW. Correction: Design and formulation of functional pluripotent stem cell-derived cardiac microtissues (Proceedings of the National Academy of Sciences (2013) 110, (E4698-E4707) DOI:10.1073/pnas.1311120110) Proceedings of the National Academy of Sciences of the United States of America. 112: E3151. DOI: 10.1073/Pnas.1311120110). |
0.449 |
|
| 2014 |
Prowse AB, Timmins NE, Yau TM, Li RK, Weisel RD, Keller G, Zandstra PW. Transforming the promise of pluripotent stem cell-derived cardiomyocytes to a therapy: challenges and solutions for clinical trials. The Canadian Journal of Cardiology. 30: 1335-49. PMID 25442434 DOI: 10.1016/J.Cjca.2014.08.005 |
0.533 |
|
| 2014 |
Witty AD, Mihic A, Tam RY, Fisher SA, Mikryukov A, Shoichet MS, Li RK, Kattman SJ, Keller G. Generation of the epicardial lineage from human pluripotent stem cells. Nature Biotechnology. 32: 1026-35. PMID 25240927 DOI: 10.1038/Nbt.3002 |
0.607 |
|
| 2014 |
Sturgeon CM, Ditadi A, Awong G, Kennedy M, Keller G. Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells. Nature Biotechnology. 32: 554-61. PMID 24837661 DOI: 10.1038/Nbt.2915 |
0.534 |
|
| 2014 |
Mihic A, Li J, Miyagi Y, Gagliardi M, Li SH, Zu J, Weisel RD, Keller G, Li RK. The effect of cyclic stretch on maturation and 3D tissue formation of human embryonic stem cell-derived cardiomyocytes. Biomaterials. 35: 2798-808. PMID 24424206 DOI: 10.1016/J.Biomaterials.2013.12.052 |
0.497 |
|
| 2014 |
Xiao Y, Zhang B, Liu H, Miklas JW, Gagliardi M, Pahnke A, Thavandiran N, Sun Y, Simmons C, Keller G, Radisic M. Microfabricated perfusable cardiac biowire: a platform that mimics native cardiac bundle. Lab On a Chip. 14: 869-82. PMID 24352498 DOI: 10.1039/C3Lc51123E |
0.383 |
|
| 2014 |
Sturgeon C, Ditadi A, Awong G, Kennedy M, Keller G. Declined Presentation: Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells Experimental Hematology. 42. DOI: 10.1016/J.Exphem.2014.07.232 |
0.536 |
|
| 2014 |
Keller G. Generation of definitive hematopoietic progenitors from human pluripotent stem cells Experimental Hematology. 42. DOI: 10.1016/J.Exphem.2014.07.005 |
0.572 |
|
| 2013 |
Thavandiran N, Dubois N, Mikryukov A, Massé S, Beca B, Simmons CA, Deshpande VS, McGarry JP, Chen CS, Nanthakumar K, Keller GM, Radisic M, Zandstra PW. Design and formulation of functional pluripotent stem cell-derived cardiac microtissues. Proceedings of the National Academy of Sciences of the United States of America. 110: E4698-707. PMID 24255110 DOI: 10.1073/Pnas.1311120110 |
0.734 |
|
| 2013 |
Chanda B, Ditadi A, Iscove NN, Keller G. Retinoic acid signaling is essential for embryonic hematopoietic stem cell development. Cell. 155: 215-27. PMID 24074870 DOI: 10.1016/J.Cell.2013.08.055 |
0.647 |
|
| 2013 |
Gaber N, Gagliardi M, Patel P, Kinnear C, Zhang C, Chitayat D, Shannon P, Jaeggi E, Tabori U, Keller G, Mital S. Fetal reprogramming and senescence in hypoplastic left heart syndrome and in human pluripotent stem cells during cardiac differentiation. The American Journal of Pathology. 183: 720-34. PMID 23871585 DOI: 10.1016/J.Ajpath.2013.05.022 |
0.48 |
|
| 2013 |
Ogawa S, Surapisitchat J, Virtanen C, Ogawa M, Niapour M, Sugamori KS, Wang S, Tamblyn L, Guillemette C, Hoffmann E, Zhao B, Strom S, Laposa RR, Tyndale RF, Grant DM, ... Keller G, et al. Three-dimensional culture and cAMP signaling promote the maturation of human pluripotent stem cell-derived hepatocytes. Development (Cambridge, England). 140: 3285-96. PMID 23861064 DOI: 10.1242/Dev.090266 |
0.543 |
|
| 2013 |
Nunes SS, Miklas JW, Liu J, Aschar-Sobbi R, Xiao Y, Zhang B, Jiang J, Massé S, Gagliardi M, Hsieh A, Thavandiran N, Laflamme MA, Nanthakumar K, Gross GJ, Backx PH, ... Keller G, et al. Biowire: a platform for maturation of human pluripotent stem cell-derived cardiomyocytes. Nature Methods. 10: 781-7. PMID 23793239 DOI: 10.1038/Nmeth.2524 |
0.508 |
|
| 2013 |
Craft AM, Ahmed N, Rockel JS, Baht GS, Alman BA, Kandel RA, Grigoriadis AE, Keller GM. Specification of chondrocytes and cartilage tissues from embryonic stem cells. Development (Cambridge, England). 140: 2597-610. PMID 23715552 DOI: 10.1242/Dev.087890 |
0.327 |
|
| 2013 |
Pourquié O, Bruneau B, Götz M, Keller G, Smith A. Stem cells and regeneration: a special issue. Development (Cambridge, England). 140: 2445. PMID 23715535 DOI: 10.1242/Dev.098350 |
0.469 |
|
| 2013 |
Sturgeon CM, Ditadi A, Clarke RL, Keller G. Defining the path to hematopoietic stem cells. Nature Biotechnology. 31: 416-8. PMID 23657396 DOI: 10.1038/Nbt.2571 |
0.561 |
|
| 2013 |
Clarke RL, Yzaguirre AD, Yashiro-Ohtani Y, Bondue A, Blanpain C, Pear WS, Speck NA, Keller G. The expression of Sox17 identifies and regulates haemogenic endothelium. Nature Cell Biology. 15: 502-10. PMID 23604320 DOI: 10.1038/Ncb2724 |
0.528 |
|
| 2013 |
Didié M, Christalla P, Rubart M, Muppala V, Döker S, Unsöld B, El-Armouche A, Rau T, Eschenhagen T, Schwoerer AP, Ehmke H, Schumacher U, Fuchs S, Lange C, Becker A, ... ... Keller G, et al. Parthenogenetic stem cells for tissue-engineered heart repair. The Journal of Clinical Investigation. 123: 1285-98. PMID 23434590 DOI: 10.1172/Jci66854 |
0.563 |
|
| 2013 |
Lieu DK, Fu JD, Chiamvimonvat N, Tung KC, McNerney GP, Huser T, Keller G, Kong CW, Li RA. Mechanism-based facilitated maturation of human pluripotent stem cell-derived cardiomyocytes. Circulation. Arrhythmia and Electrophysiology. 6: 191-201. PMID 23392582 DOI: 10.1161/Circep.111.973420 |
0.521 |
|
| 2013 |
Terrenoire C, Wang K, Tung KW, Chung WK, Pass RH, Lu JT, Jean JC, Omari A, Sampson KJ, Kotton DN, Keller G, Kass RS. Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics. The Journal of General Physiology. 141: 61-72. PMID 23277474 DOI: 10.1083/Jcb2001Oia3 |
0.377 |
|
| 2013 |
El-Mounayri O, Mihic A, Shikatani EA, Gagliardi M, Steinbach SK, Dubois N, Dacosta R, Li RK, Keller G, Husain M. Serum-free differentiation of functional human coronary-like vascular smooth muscle cells from embryonic stem cells. Cardiovascular Research. 98: 125-35. PMID 23213107 DOI: 10.1093/Cvr/Cvs357 |
0.783 |
|
| 2012 |
Kennedy M, Awong G, Sturgeon CM, Ditadi A, LaMotte-Mohs R, Zúñiga-Pflücker JC, Keller G. T lymphocyte potential marks the emergence of definitive hematopoietic progenitors in human pluripotent stem cell differentiation cultures. Cell Reports. 2: 1722-35. PMID 23219550 DOI: 10.1016/J.Celrep.2012.11.003 |
0.594 |
|
| 2012 |
Serena E, Cimetta E, Zatti S, Zaglia T, Zagallo M, Keller G, Elvassore N. Micro-arrayed human embryonic stem cells-derived cardiomyocytes for in vitro functional assay. Plos One. 7: e48483. PMID 23152776 DOI: 10.1371/Journal.Pone.0048483 |
0.484 |
|
| 2012 |
Paige SL, Thomas S, Stoick-Cooper CL, Wang H, Maves L, Sandstrom R, Pabon L, Reinecke H, Pratt G, Keller G, Moon RT, Stamatoyannopoulos J, Murry CE. A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac development. Cell. 151: 221-32. PMID 22981225 DOI: 10.1016/J.Cell.2012.08.027 |
0.57 |
|
| 2012 |
Nostro MC, Keller G. Generation of beta cells from human pluripotent stem cells: Potential for regenerative medicine. Seminars in Cell & Developmental Biology. 23: 701-10. PMID 22750147 DOI: 10.1016/J.Semcdb.2012.06.010 |
0.499 |
|
| 2012 |
Sturgeon CM, Chicha L, Ditadi A, Zhou Q, McGrath KE, Palis J, Hammond SM, Wang S, Olson EN, Keller G. Primitive erythropoiesis is regulated by miR-126 via nonhematopoietic Vcam-1+ cells. Developmental Cell. 23: 45-57. PMID 22749417 DOI: 10.1016/J.Devcel.2012.05.021 |
0.389 |
|
| 2012 |
Burridge PW, Keller G, Gold JD, Wu JC. Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming. Cell Stem Cell. 10: 16-28. PMID 22226352 DOI: 10.1016/J.Stem.2011.12.013 |
0.573 |
|
| 2012 |
Ungrin MD, Clarke G, Yin T, Niebrugge S, Nostro MC, Sarangi F, Wood G, Keller G, Zandstra PW. Rational bioprocess design for human pluripotent stem cell expansion and endoderm differentiation based on cellular dynamics. Biotechnology and Bioengineering. 109: 853-66. PMID 22139975 DOI: 10.1002/Bit.24375 |
0.561 |
|
| 2012 |
Micallef SJ, Li X, Schiesser JV, Hirst CE, Yu QC, Lim SM, Nostro MC, Elliott DA, Sarangi F, Harrison LC, Keller G, Elefanty AG, Stanley EG. INS(GFP/w) human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cells. Diabetologia. 55: 694-706. PMID 22120512 DOI: 10.1007/S00125-011-2379-Y |
0.543 |
|
| 2012 |
Ishida M, El-Mounayri O, Kattman S, Zandstra P, Sakamoto H, Ogawa M, Keller G, Husain M. Regulated expression and role of c-Myb in the cardiovascular-directed differentiation of mouse embryonic stem cells. Circulation Research. 110: 253-64. PMID 22116818 DOI: 10.1161/Circresaha.111.259499 |
0.485 |
|
| 2012 |
Basford CL, Prentice KJ, Hardy AB, Sarangi F, Micallef SJ, Li X, Guo Q, Elefanty AG, Stanley EG, Keller G, Allister EM, Nostro MC, Wheeler MB. The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells. Diabetologia. 55: 358-71. PMID 22075915 DOI: 10.1007/S00125-011-2335-X |
0.496 |
|
| 2012 |
Keller GM, Webb S, Kennedy M. Hematopoietic Development of ES Cells in Culture. Methods in Molecular Medicine. 63: 209-30. PMID 21437810 DOI: 10.1385/1-59259-140-X:209 |
0.358 |
|
| 2012 |
El-Mounayri O, Mihic A, Shikatani E, Gagliardi M, Dubois N, Steinbach SK, DaCosta R, Li R, Keller G, Husain M. 523 Serum-Free Differentiation of Functional Human Coronary Vascular Smooth Muscle Cells from Embryonic Stem Cells Canadian Journal of Cardiology. 28. DOI: 10.1016/J.Cjca.2012.07.477 |
0.514 |
|
| 2012 |
Wang K, Terrenoire C, Sampson KJ, Lyer V, Chan Tung KW, Lu J, Chung W, Pass RH, Keller G, Kotton DN, Kass RS. Patient-Specific Inducible Pluripotent Stem Cells Reveal Mechanism of Personalized Therapy for an Inherited Cardiac Arrhythmia Biophysical Journal. 102: 539a. DOI: 10.1016/J.Bpj.2011.11.2947 |
0.411 |
|
| 2011 |
Fu JD, Rushing SN, Lieu DK, Chan CW, Kong CW, Geng L, Wilson KD, Chiamvimonvat N, Boheler KR, Wu JC, Keller G, Hajjar RJ, Li RA. Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes. Plos One. 6: e27417. PMID 22110643 DOI: 10.1371/Journal.Pone.0027417 |
0.326 |
|
| 2011 |
Wang K, Terrenoire C, Sampson KJ, Iyer V, Osteen JD, Lu J, Keller G, Kotton DN, Kass RS. Biophysical properties of slow potassium channels in human embryonic stem cell derived cardiomyocytes implicate subunit stoichiometry. The Journal of Physiology. 589: 6093-104. PMID 22025662 DOI: 10.1113/Jphysiol.2011.220863 |
0.457 |
|
| 2011 |
Dubois NC, Craft AM, Sharma P, Elliott DA, Stanley EG, Elefanty AG, Gramolini A, Keller G. SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells. Nature Biotechnology. 29: 1011-8. PMID 22020386 DOI: 10.1038/Nbt.2005 |
0.799 |
|
| 2011 |
Kubo A, Stull R, Takeuchi M, Bonham K, Gouon-Evans V, Sho M, Iwano M, Saito Y, Keller G, Snodgrass R. Pdx1 and Ngn3 overexpression enhances pancreatic differentiation of mouse ES cell-derived endoderm population. Plos One. 6: e24058. PMID 21931641 DOI: 10.1371/Journal.Pone.0024058 |
0.444 |
|
| 2011 |
Zhang X, Yalcin S, Lee DF, Yeh TY, Lee SM, Su J, Mungamuri SK, Rimmelé P, Kennedy M, Sellers R, Landthaler M, Tuschl T, Chi NW, Lemischka I, Keller G, et al. FOXO1 is an essential regulator of pluripotency in human embryonic stem cells. Nature Cell Biology. 13: 1092-9. PMID 21804543 DOI: 10.1038/Ncb2293 |
0.57 |
|
| 2011 |
Han S, Dziedzic N, Gadue P, Keller GM, Gouon-Evans V. An endothelial cell niche induces hepatic specification through dual repression of Wnt and Notch signaling. Stem Cells (Dayton, Ohio). 29: 217-28. PMID 21732480 DOI: 10.1002/stem.576 |
0.338 |
|
| 2011 |
Green MD, Chen A, Nostro MC, d'Souza SL, Schaniel C, Lemischka IR, Gouon-Evans V, Keller G, Snoeck HW. Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells. Nature Biotechnology. 29: 267-72. PMID 21358635 DOI: 10.1038/Nbt.1788 |
0.601 |
|
| 2011 |
Kattman SJ, Witty AD, Gagliardi M, Dubois NC, Niapour M, Hotta A, Ellis J, Keller G. Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines. Cell Stem Cell. 8: 228-40. PMID 21295278 DOI: 10.1016/J.Stem.2010.12.008 |
0.781 |
|
| 2011 |
Nostro MC, Sarangi F, Ogawa S, Holtzinger A, Corneo B, Li X, Micallef SJ, Park IH, Basford C, Wheeler MB, Daley GQ, Elefanty AG, Stanley EG, Keller G. Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells. Development (Cambridge, England). 138: 861-71. PMID 21270052 DOI: 10.1242/dev.055236 |
0.481 |
|
| 2011 |
Wang K, Terrenoire C, Sampson KJ, Osteen JD, Lu J, Gagliardi M, Keller G, Kass RS. Biophysical Characterization of Iks Channels in Cardiomyocytes Derived from Human Embryonic Stem Cells Reveals Insights Into Stoichiometry of KCNQ1-KCNE1 Complex Biophysical Journal. 100: 439a. DOI: 10.1016/J.Bpj.2010.12.2588 |
0.326 |
|
| 2010 |
Irion S, Clarke RL, Luche H, Kim I, Morrison SJ, Fehling HJ, Keller GM. Temporal specification of blood progenitors from mouse embryonic stem cells and induced pluripotent stem cells. Development (Cambridge, England). 137: 2829-39. PMID 20659975 DOI: 10.1242/Dev.042119 |
0.486 |
|
| 2010 |
Zhou Z, French DL, Ma G, Eisenstein S, Chen Y, Divino CM, Keller G, Chen SH, Pan PY. Development and function of myeloid-derived suppressor cells generated from mouse embryonic and hematopoietic stem cells. Stem Cells (Dayton, Ohio). 28: 620-32. PMID 20073041 DOI: 10.1002/Stem.301 |
0.492 |
|
| 2010 |
Grigoriadis AE, Kennedy M, Bozec A, Brunton F, Stenbeck G, Park IH, Wagner EF, Keller GM. Directed differentiation of hematopoietic precursors and functional osteoclasts from human ES and iPS cells. Blood. 115: 2769-76. PMID 20065292 DOI: 10.1182/Blood-2009-07-234690 |
0.448 |
|
| 2010 |
Kubo A, Kim YH, Irion S, Kasuda S, Takeuchi M, Ohashi K, Iwano M, Dohi Y, Saito Y, Snodgrass R, Keller G. The homeobox gene Hex regulates hepatocyte differentiation from embryonic stem cell-derived endoderm. Hepatology (Baltimore, Md.). 51: 633-41. PMID 20063280 DOI: 10.1002/Hep.23293 |
0.492 |
|
| 2010 |
Adler ED, Chen VC, Bystrup A, Kaplan AD, Giovannone S, Briley-Saebo K, Young W, Kattman S, Mani V, Laflamme M, Zhu WZ, Fayad Z, Keller G. The cardiomyocyte lineage is critical for optimization of stem cell therapy in a mouse model of myocardial infarction. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1073-81. PMID 19940262 DOI: 10.1096/Fj.09-135426 |
0.522 |
|
| 2010 |
Song H, Yoon C, Kattman SJ, Dengler J, Massé S, Thavaratnam T, Gewarges M, Nanthakumar K, Rubart M, Keller GM, Radisic M, Zandstra PW. Interrogating functional integration between injected pluripotent stem cell-derived cells and surrogate cardiac tissue. Proceedings of the National Academy of Sciences of the United States of America. 107: 3329-34. PMID 19846783 DOI: 10.1073/Pnas.0905729106 |
0.433 |
|
| 2009 |
Adler ED, Bystrup A, Briley-Saebo KC, Mani V, Young W, Giovanonne S, Altman P, Kattman SJ, Frank JA, Weinmann HJ, Keller GM, Fayad ZA. In vivo detection of embryonic stem cell-derived cardiovascular progenitor cells using Cy3-labeled Gadofluorine M in murine myocardium. Jacc. Cardiovascular Imaging. 2: 1114-22. PMID 19761992 DOI: 10.1016/J.Jcmg.2009.04.015 |
0.437 |
|
| 2009 |
Gadue P, Gouon-Evans V, Cheng X, Wandzioch E, Zaret KS, Grompe M, Streeter PR, Keller GM. Generation of monoclonal antibodies specific for cell surface molecules expressed on early mouse endoderm. Stem Cells (Dayton, Ohio). 27: 2103-13. PMID 19522011 DOI: 10.1002/Stem.147 |
0.38 |
|
| 2009 |
Ellis J, Bruneau BG, Keller G, Lemischka IR, Nagy A, Rossant J, Srivastava D, Zandstra PW, Stanford WL. Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell Stem Cell. 4: 198-9; author reply . PMID 19265656 DOI: 10.1016/J.Stem.2009.02.010 |
0.495 |
|
| 2009 |
Uzzaman M, Keller G, Germano IM. In vivo gene delivery by embryonic-stem-cell-derived astrocytes for malignant gliomas. Neuro-Oncology. 11: 102-8. PMID 18676359 DOI: 10.1215/15228517-2008-056 |
0.449 |
|
| 2009 |
Grigoriadis A, Kennedy M, Bozec A, Stenbeck G, Wagner E, Keller G. Directed differentiation of human embryonic stem cells and induced pluripotent stem cells to functional osteoclasts Bone. 44: S216. DOI: 10.1016/J.Bone.2009.03.051 |
0.588 |
|
| 2008 |
Chen VC, Stull R, Joo D, Cheng X, Keller G. Notch signaling respecifies the hemangioblast to a cardiac fate. Nature Biotechnology. 26: 1169-78. PMID 18820686 DOI: 10.1038/Nbt.1497 |
0.497 |
|
| 2008 |
Cheng X, Huber TL, Chen VC, Gadue P, Keller GM. Numb mediates the interaction between Wnt and Notch to modulate primitive erythropoietic specification from the hemangioblast. Development (Cambridge, England). 135: 3447-58. PMID 18799543 DOI: 10.1242/dev.025916 |
0.331 |
|
| 2008 |
Germano IM, Uzzaman M, Keller G. Gene delivery by embryonic stem cells for malignant glioma therapy: hype or hope? Cancer Biology & Therapy. 7: 1341-7. PMID 18719364 DOI: 10.4161/Cbt.7.9.6711 |
0.455 |
|
| 2008 |
Mani V, Adler E, Briley-Saebo KC, Bystrup A, Fuster V, Keller G, Fayad ZA. Serial in vivo positive contrast MRI of iron oxide-labeled embryonic stem cell-derived cardiac precursor cells in a mouse model of myocardial infarction. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 60: 73-81. PMID 18581415 DOI: 10.1002/Mrm.21642 |
0.488 |
|
| 2008 |
Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M, Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Keller GM. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population. Nature. 453: 524-8. PMID 18432194 DOI: 10.1038/Nature06894 |
0.522 |
|
| 2008 |
Nostro MC, Cheng X, Keller GM, Gadue P. Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood. Cell Stem Cell. 2: 60-71. PMID 18371422 DOI: 10.1016/j.stem.2007.10.011 |
0.343 |
|
| 2008 |
Murry CE, Keller G. Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell. 132: 661-80. PMID 18295582 DOI: 10.1016/J.Cell.2008.02.008 |
0.601 |
|
| 2008 |
de Bruijn M, Mikkola H, Snoeck H, Keller G. Highlights from Philadelphia: ISSCR 2008 Cell Stem Cell. 3: 259-264. DOI: 10.1016/J.Stem.2008.08.015 |
0.408 |
|
| 2007 |
Irion S, Luche H, Gadue P, Fehling HJ, Kennedy M, Keller G. Identification and targeting of the ROSA26 locus in human embryonic stem cells. Nature Biotechnology. 25: 1477-82. PMID 18037879 DOI: 10.1038/Nbt1362 |
0.542 |
|
| 2007 |
Kattman SJ, Adler ED, Keller GM. Specification of multipotential cardiovascular progenitor cells during embryonic stem cell differentiation and embryonic development. Trends in Cardiovascular Medicine. 17: 240-6. PMID 17936206 DOI: 10.1016/j.tcm.2007.08.004 |
0.521 |
|
| 2007 |
Vigneau C, Polgar K, Striker G, Elliott J, Hyink D, Weber O, Fehling HJ, Keller G, Burrow C, Wilson P. Mouse embryonic stem cell-derived embryoid bodies generate progenitors that integrate long term into renal proximal tubules in vivo. Journal of the American Society of Nephrology : Jasn. 18: 1709-20. PMID 17475814 DOI: 10.1681/Asn.2006101078 |
0.497 |
|
| 2007 |
Kennedy M, D'Souza SL, Lynch-Kattman M, Schwantz S, Keller G. Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures. Blood. 109: 2679-87. PMID 17148580 DOI: 10.1182/Blood-2006-09-047704 |
0.58 |
|
| 2007 |
Zafonte BT, Liu S, Lynch-Kattman M, Torregroza I, Benvenuto L, Kennedy M, Keller G, Evans T. Smad1 expands the hemangioblast population within a limited developmental window. Blood. 109: 516-23. PMID 16990609 DOI: 10.1182/Blood-2006-02-004564 |
0.494 |
|
| 2007 |
French DL, Jirouskova M, Kennedy M, Coller BS, Keller G. Generation of Megakaryocytes from Human Embryonic Stem Cells. Blood. 110: 1265-1265. DOI: 10.1182/Blood.V110.11.1265.1265 |
0.52 |
|
| 2006 |
Gouon-Evans V, Boussemart L, Gadue P, Nierhoff D, Koehler CI, Kubo A, Shafritz DA, Keller G. BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm. Nature Biotechnology. 24: 1402-11. PMID 17086172 DOI: 10.1038/Nbt1258 |
0.515 |
|
| 2006 |
Kattman SJ, Huber TL, Keller GM. Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages. Developmental Cell. 11: 723-32. PMID 17084363 DOI: 10.1016/j.devcel.2006.10.002 |
0.389 |
|
| 2006 |
Gadue P, Huber TL, Paddison PJ, Keller GM. Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 16806-11. PMID 17077151 DOI: 10.1073/pnas.0603916103 |
0.323 |
|
| 2006 |
Germano IM, Uzzaman M, Benveniste RJ, Zaurova M, Keller G. Apoptosis in human glioblastoma cells produced using embryonic stem cell-derived astrocytes expressing tumor necrosis factor-related apoptosis-inducing ligand. Journal of Neurosurgery. 105: 88-95. PMID 16871882 DOI: 10.3171/Jns.2006.105.1.88 |
0.492 |
|
| 2006 |
Arufe MC, Lu M, Kubo A, Keller G, Davies TF, Lin RY. Directed differentiation of mouse embryonic stem cells into thyroid follicular cells. Endocrinology. 147: 3007-15. PMID 16497809 DOI: 10.1210/En.2005-1239 |
0.543 |
|
| 2006 |
Willey S, Ayuso-Sacido A, Zhang H, Fraser ST, Sahr KE, Adlam MJ, Kyba M, Daley GQ, Keller G, Baron MH. Acceleration of mesoderm development and expansion of hematopoietic progenitors in differentiating ES cells by the mouse Mix-like homeodomain transcription factor. Blood. 107: 3122-30. PMID 16403910 DOI: 10.1182/Blood-2005-10-4120 |
0.579 |
|
| 2006 |
Matsumoto N, Kubo A, Liu H, Akita K, Laub F, Ramirez F, Keller G, Friedman SL. Developmental regulation of yolk sac hematopoiesis by Kruppel-like factor 6. Blood. 107: 1357-65. PMID 16234353 DOI: 10.1182/Blood-2005-05-1916 |
0.535 |
|
| 2006 |
Pan B, Kennedy M, Keller G, Najfeld V, Walsh CE. Knockdown of the Fanconi Anemia Gene FANCD2 Directly Affects Hematopoiesis in Human Embryonic Stem Cells. Blood. 108: 1318-1318. DOI: 10.1182/Blood.V108.11.1318.1318 |
0.492 |
|
| 2006 |
Kasuda S, Sakurai Y, Kubo A, Shima M, Keller G, Yoshioka A. Establishment of ES Cells Secreting Human Factor VIII for Hemophilia A-Targeted Cell Therapy. Blood. 108: 1012-1012. DOI: 10.1182/Blood.V108.11.1012.1012 |
0.497 |
|
| 2005 |
Uzzaman M, Benveniste RJ, Keller G, Germano IM. Embryonic stem cell-derived astrocytes: a novel gene therapy vector for brain tumors. Neurosurgical Focus. 19: E6. PMID 16190605 DOI: 10.3171/Foc.2005.19.3.7 |
0.431 |
|
| 2005 |
Kouskoff V, Lacaud G, Schwantz S, Fehling HJ, Keller G. Sequential development of hematopoietic and cardiac mesoderm during embryonic stem cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. 102: 13170-5. PMID 16141334 DOI: 10.1073/Pnas.0501672102 |
0.58 |
|
| 2005 |
Gadue P, Huber TL, Nostro MC, Kattman S, Keller GM. Germ layer induction from embryonic stem cells. Experimental Hematology. 33: 955-64. PMID 16140142 DOI: 10.1016/j.exphem.2005.06.009 |
0.46 |
|
| 2005 |
Benveniste RJ, Keller G, Germano I. Embryonic stem cell-derived astrocytes expressing drug-inducible transgenes: differentiation and transplantion into the mouse brain. Journal of Neurosurgery. 103: 115-23. PMID 16121982 DOI: 10.3171/Jns.2005.103.1.0115 |
0.5 |
|
| 2005 |
Keller G. Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes & Development. 19: 1129-55. PMID 15905405 DOI: 10.1101/Gad.1303605 |
0.552 |
|
| 2005 |
Kubo A, Chen V, Kennedy M, Zahradka E, Daley GQ, Keller G. The homeobox gene HEX regulates proliferation and differentiation of hemangioblasts and endothelial cells during ES cell differentiation. Blood. 105: 4590-7. PMID 15728128 DOI: 10.1182/Blood-2004-10-4137 |
0.576 |
|
| 2005 |
D'Souza SL, Elefanty AG, Keller G. SCL/Tal-1 is essential for hematopoietic commitment of the hemangioblast but not for its development. Blood. 105: 3862-70. PMID 15677567 DOI: 10.1182/Blood-2004-09-3611 |
0.546 |
|
| 2005 |
Irion S, Luche H, Fehling HJ, Keller G. Serum Free Induction of a Lympho-Hematopoietic Precursor Population from Murine Embryonic Stem Cells. Blood. 106: 3605-3605. DOI: 10.1182/Blood.V106.11.3605.3605 |
0.55 |
|
| 2005 |
Henckaerts E, Zeltner N, Kattman S, Dutheil N, Ward P, Kennedy M, Clement N, Rebollo P, Keller G, Linden RM. 20. Targeted Gene Delivery to Embryonic Stem Cells Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.023 |
0.501 |
|
| 2004 |
Lacaud G, Keller G, Kouskoff V. Tracking mesoderm formation and specification to the hemangioblast in vitro. Trends in Cardiovascular Medicine. 14: 314-7. PMID 15596108 DOI: 10.1016/J.Tcm.2004.09.004 |
0.529 |
|
| 2004 |
Ku HT, Zhang N, Kubo A, O'Connor R, Mao M, Keller G, Bromberg JS. Committing embryonic stem cells to early endocrine pancreas in vitro. Stem Cells (Dayton, Ohio). 22: 1205-17. PMID 15579640 DOI: 10.1634/Stemcells.2004-0027 |
0.386 |
|
| 2004 |
Huber TL, Kouskoff V, Fehling HJ, Palis J, Keller G. Haemangioblast commitment is initiated in the primitive streak of the mouse embryo. Nature. 432: 625-30. PMID 15577911 DOI: 10.1038/Nature03122 |
0.511 |
|
| 2004 |
Ramírez-Bergeron DL, Runge A, Dahl KD, Fehling HJ, Keller G, Simon MC. Hypoxia affects mesoderm and enhances hemangioblast specification during early development. Development (Cambridge, England). 131: 4623-34. PMID 15342485 DOI: 10.1242/Dev.01310 |
0.486 |
|
| 2004 |
Kubo A, Shinozaki K, Shannon JM, Kouskoff V, Kennedy M, Woo S, Fehling HJ, Keller G. Development of definitive endoderm from embryonic stem cells in culture. Development (Cambridge, England). 131: 1651-62. PMID 14998924 DOI: 10.1242/Dev.01044 |
0.566 |
|
| 2004 |
Martin R, Lahlil R, Damert A, Miquerol L, Nagy A, Keller G, Hoang T. SCL interacts with VEGF to suppress apoptosis at the onset of hematopoiesis. Development (Cambridge, England). 131: 693-702. PMID 14729577 DOI: 10.1242/Dev.00968 |
0.42 |
|
| 2004 |
Lieber JG, Webb S, Suratt BT, Young SK, Johnson GL, Keller GM, Worthen GS. The in vitro production and characterization of neutrophils from embryonic stem cells. Blood. 103: 852-9. PMID 14525782 DOI: 10.1182/Blood-2003-04-1030 |
0.434 |
|
| 2004 |
Lacaud G, Kouskoff V, Trumble A, Schwantz S, Keller G. Haploinsufficiency of Runx1 results in the acceleration of mesodermal development and hemangioblast specification upon in vitro differentiation of ES cells. Blood. 103: 886-889. PMID 14525762 DOI: 10.1182/Blood-2003-06-2149 |
0.536 |
|
| 2004 |
Keller G, Kubo A, Fehling HJ, Kouskoff V. 922. Deriving tissues from embryonic stem cells Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.828 |
0.611 |
|
| 2003 |
Lieber JG, Keller GM, Worthen GS. The in Vitro Differentiation of Mouse Embryonic Stem Cells into Neutrophils Methods in Enzymology. 365: 129-142. PMID 14696342 DOI: 10.1016/S0076-6879(03)65009-3 |
0.403 |
|
| 2003 |
Kennedy M, Keller GM. Hematopoietic Commitment of ES Cells in Culture Methods in Enzymology. 365: 39-59. PMID 14696336 DOI: 10.1016/S0076-6879(03)65003-2 |
0.329 |
|
| 2003 |
Levantini E, Giorgetti A, Cerisoli F, Traggiai E, Guidi A, Martin R, Acampora D, Aplan PD, Keller G, Simeone A, Iscove NN, Hoang T, Magli MC. Unsuspected role of the brain morphogenetic gene Otx1 in hematopoiesis. Proceedings of the National Academy of Sciences of the United States of America. 100: 10299-303. PMID 12934017 DOI: 10.1073/Pnas.1734071100 |
0.427 |
|
| 2003 |
Fehling HJ, Lacaud G, Kubo A, Kennedy M, Robertson S, Keller G, Kouskoff V. Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation. Development (Cambridge, England). 130: 4217-27. PMID 12874139 DOI: 10.1242/Dev.00589 |
0.595 |
|
| 2003 |
Lin RY, Kubo A, Keller GM, Davies TF. Committing embryonic stem cells to differentiate into thyrocyte-like cells in vitro Endocrinology. 144: 2644-2649. PMID 12746328 DOI: 10.1210/En.2002-0122 |
0.422 |
|
| 2003 |
Mohn D, Chen SW, Dias DC, Weinstein DC, Dyer MA, Sahr K, Ducker CE, Zahradka E, Keller G, Zaret KS, Gudas LJ, Baron MH. Mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 226: 446-59. PMID 12619131 DOI: 10.1002/Dvdy.10263 |
0.565 |
|
| 2003 |
Matsumoto N, Kubo A, Liu H, Laub F, Ramirez F, Keller G, Friedman SL. 267 Key role of KLF6 in hepatocellular differentiation from embryonic stem cells Hepatology. 38: 285-285. DOI: 10.1016/S0270-9139(03)80310-5 |
0.543 |
|
| 2002 |
Yu TS, Moctezuma-Anaya M, Kubo A, Keller G, Robertson S. The heart LIM protein gene (Hlp), expressed in the developing and adult heart, defines a new tissue-specific LIM-only protein family. Mechanisms of Development. 116: 187-92. PMID 12128222 DOI: 10.1016/S0925-4773(02)00139-9 |
0.352 |
|
| 2002 |
Lacaud G, Gore L, Kennedy M, Kouskoff V, Kingsley P, Hogan C, Carlsson L, Speck N, Palis J, Keller G. Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro. Blood. 100: 458-66. PMID 12091336 DOI: 10.1182/Blood-2001-12-0321 |
0.433 |
|
| 2002 |
Hogan CJ, Shpall EJ, Keller G. Differential long-term and multilineage engraftment potential from subfractions of human CD34+ cord blood cells transplanted into NOD/SCID mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 413-8. PMID 11782553 DOI: 10.1073/Pnas.012336799 |
0.399 |
|
| 2001 |
Lacaud G, Robertson S, Palis J, Kennedy M, Keller G. Regulation of hemangioblast development. Annals of the New York Academy of Sciences. 938: 96-107; discussion 1. PMID 11458531 DOI: 10.1111/J.1749-6632.2001.Tb03578.X |
0.575 |
|
| 2000 |
Garrington TP, Ishizuka T, Papst PJ, Chayama K, Webb S, Yujiri T, Sun W, Sather S, Russell DM, Gibson SB, Keller G, Gelfand EW, Johnson GL. MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells. The Embo Journal. 19: 5387-95. PMID 11032806 DOI: 10.1093/Emboj/19.20.5387 |
0.365 |
|
| 1999 |
Robertson S, Kennedy M, Keller G. Hematopoietic Commitment during Embryogenesis Annals of the New York Academy of Sciences. 872: 9-16. PMID 10372106 DOI: 10.1111/J.1749-6632.1999.Tb08448.X |
0.531 |
|
| 1999 |
Keller G, Lacaud G, Robertson S. Development of the hematopoietic system in the mouse Experimental Hematology. 27: 777-787. PMID 10340392 DOI: 10.1016/S0301-472X(99)00024-7 |
0.472 |
|
| 1998 |
Lacaud G, Carlsson L, Keller G. Identification of a Fetal Hematopoietic Precursor with B Cell, T Cell, and Macrophage Potential Immunity. 9: 827-838. PMID 9881973 DOI: 10.1016/S1074-7613(00)80648-2 |
0.454 |
|
| 1998 |
Epner E, Reik A, Cimbora D, Telling A, Bender MA, Fiering S, Enver T, Martin DI, Kennedy M, Keller G, Groudine M. The beta-globin LCR is not necessary for an open chromatin structure or developmentally regulated transcription of the native mouse beta-globin locus. Molecular Cell. 2: 447-55. PMID 9809066 DOI: 10.1016/S1097-2765(00)80144-6 |
0.322 |
|
| 1998 |
Palis J, Kennedy M, McGrath KE, Keller G. Commitment to Hematopoietic Fates Begins During Early Gastrulation in the Mammalian Embryo • 292 Pediatric Research. 43: 52-52. DOI: 10.1203/00006450-199804001-00313 |
0.506 |
|
| 1998 |
Keller G, Wall C, Fong AZC, Hawley TS, Hawley RG. Overexpression of HOX11 Leads to the Immortalization of Embryonic Precursors With Both Primitive and Definitive Hematopoietic Potential Blood. 92: 877-887. DOI: 10.1182/Blood.V92.3.877.415K11_877_887 |
0.53 |
|
| 1997 |
Kennedy M, Firpo M, Choi K, Wall C, Robertson S, Kabrun N, Keller G. A common precursor for primitive erythropoiesis and definitive haematopoiesis. Nature. 386: 488-493. PMID 9087406 DOI: 10.1038/386488A0 |
0.586 |
|
| 1997 |
Hogan CJ, Shpall EJ, McNulty O, McNiece I, Dick JE, Shultz LD, Keller G. Engraftment and development of human CD34+-enriched cells from umbilical cord blood in NOD/LtSz-scid/scid mice Blood. 90: 85-96. DOI: 10.1182/Blood.V90.1.85.85_85_96 |
0.51 |
|
| 1997 |
Mikhail AA, Beck EX, Shafer A, Barut B, Gbur JS, Zupancic TJ, Schweitzer AC, Cioffi JA, Lacaud G, Ouyang B, Keller G, Snodgrass HR. Leptin Stimulates Fetal and Adult Erythroid and Myeloid Development Blood. 89: 1507-1512. DOI: 10.1182/Blood.V89.5.1507.1507_1507_1512 |
0.454 |
|
| 1995 |
Keller GM. In vitro differentiation of embryonic stem cells Current Opinion in Cell Biology. 7: 862-869. PMID 8608017 DOI: 10.1016/0955-0674(95)80071-9 |
0.509 |
|
| 1995 |
Carlsson L, Candéias S, Staerz U, Keller G. Expression of Fc gamma RIII defines distinct subpopulations of fetal liver B cell and myeloid precursors. European Journal of Immunology. 25: 2308-2317. PMID 7664793 DOI: 10.1002/Eji.1830250829 |
0.468 |
|
| 1994 |
Tsai FY, Keller G, Kuo FC, Weiss M, Chen J, Rosenblatt M, Alt FW, Orkin SH. An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature. 371: 221-6. PMID 8078582 DOI: 10.1038/371221A0 |
0.516 |
|
| 1994 |
Weiss MJ, Keller G, Orkin SH. Novel insights into erythroid development revealed through in vitro differentiation of GATA-1- embryonic stem cells Genes and Development. 8: 1184-1197. PMID 7926723 DOI: 10.1101/Gad.8.10.1184 |
0.562 |
|
| 1993 |
Keller G, Kennedy M, Papayannopoulou T, Wiles MV. Hematopoietic commitment during embryonic stem cell differentiation in culture. Molecular and Cellular Biology. 13: 473-486. PMID 8417345 DOI: 10.1128/Mcb.13.1.473 |
0.505 |
|
| 1993 |
Choi K, Kennedy M, Keller G. Expression of a gene encoding a unique protein-tyrosine kinase within specific fetal- and adult-derived hematopoietic lineages. Proceedings of the National Academy of Sciences of the United States of America. 90: 5747-5751. PMID 7685911 DOI: 10.1073/Pnas.90.12.5747 |
0.473 |
|
| 1993 |
Simon MC, Pevny L, Wiles MV, Keller G, Costantini F, Orkin SH. Rescue of erythroid development in gene targeted GATA-1- mouse embryonic stem cells. Nature Genetics. 1: 92-8. PMID 1302015 DOI: 10.1038/Ng0592-92 |
0.545 |
|
| 1992 |
Keller G. Hematopoietic stem cells Current Opinion in Immunology. 4: 133-139. PMID 1605905 DOI: 10.1016/0960-9822(92)90881-A |
0.526 |
|
| 1992 |
Keller G. Clonal analysis of hematopoietic stem cell development in vivo Current Topics in Microbiology and Immunology. 177: 41-57. PMID 1353433 |
0.488 |
|
| 1992 |
Kennedy M, Beug H, Wagner E, Keller G. Factor-dependent erythroid cell lines derived from mice transplanted with hematopoietic cells expressing the v-src oncogene Blood. 79: 180-190. DOI: 10.1182/Blood.V79.1.180.180 |
0.43 |
|
| 1991 |
Kiefer F, Wagner E, Keller G. Fractionation of mouse bone marrow by adherence separates primitive hematopoietic stem cells from in vitro colony-forming cells and spleen colony-forming cells Blood. 78: 2577-2582. DOI: 10.1182/Blood.V78.10.2577.Bloodjournal78102577 |
0.493 |
|
| 1990 |
Keller G, Snodgrass R. Life span of multipotential hematopoietic stem cells in vivo. Journal of Experimental Medicine. 171: 1407-1418. PMID 2159048 DOI: 10.1084/Jem.171.5.1407 |
0.57 |
|
| 1989 |
Keller G, Wagner EF. Expression of v-src induces a myeloproliferative disease in bone-marrow-reconstituted mice. Genes & Development. 3: 827-37. PMID 2568314 DOI: 10.1101/Gad.3.6.827 |
0.359 |
|
| 1988 |
Iscove N, Fagg B, Keller G. A soluble activity from adherent marrow cells cooperates with IL 3 in stimulating growth of pluripotential hematopoietic precursors. Blood. 71: 953-957. DOI: 10.1182/Blood.V71.4.953.Bloodjournal714953 |
0.318 |
|
| 1987 |
Keller G, Wagner EF. Efficient expression of foreign genes in mice reconstituted with retrovirus-infected bone marrow cells. Cold Spring Harbor Symposia On Quantitative Biology. 1053-8. PMID 3472752 DOI: 10.1101/Sqb.1986.051.01.122 |
0.317 |
|
| 1987 |
Snodgrass R, Keller G. Clonal fluctuation within the haematopoietic system of mice reconstituted with retrovirus-infected stem cells. The Embo Journal. 6: 3955-3960. DOI: 10.1002/J.1460-2075.1987.Tb02737.X |
0.437 |
|
| 1986 |
Reimann J, Heeg K, Wagner H, Keller G, Wagner EF. Introduction of a selectable gene into murine T-lymphoblasts by a retroviral vector. Journal of Immunological Methods. 89: 93-101. PMID 3486230 DOI: 10.1016/0022-1759(86)90036-0 |
0.306 |
|
| 1986 |
Anagnou NP, Karlsson S, Moulton AD, Keller G, Nienhuis AW. Promoter sequences required for function of the human gamma globin gene in erythroid cells The Embo Journal. 5: 121-126. PMID 3007109 DOI: 10.1002/J.1460-2075.1986.Tb04185.X |
0.355 |
|
| 1985 |
Keller G, Paige C, Gilboa E, Wagner EF. Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors Nature. 318: 149-154. PMID 3903518 DOI: 10.1038/318149A0 |
0.408 |
|
| 1985 |
Wagner EF, Keller G, Gilboa E, Rüther U, Stewart C. Gene transfer into murine stem cells and mice using retroviral vectors Cold Spring Harbor Symposia On Quantitative Biology. 50: 691-700. PMID 3868504 DOI: 10.1101/Sqb.1985.050.01.085 |
0.439 |
|
| 1984 |
Keller G, Holmes W, Phillips RA. Clonal generation of multipotent and unipotent hemopoietic blast cell colonies in vitro Journal of Cellular Physiology. 120: 29-35. PMID 6736135 DOI: 10.1002/Jcp.1041200105 |
0.361 |
|
| 1983 |
Joyner A, Keller G, Phillips RA, Bernstein A. Retrovirus transfer of a bacterial gene into mouse haematopoietic progenitor cells. Nature. 305: 556-8. PMID 6312324 DOI: 10.1038/305556A0 |
0.459 |
|
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