Minna Woo - Publications

Affiliations: 
Medical Biophysics University of Toronto, Toronto, ON, Canada 
Area:
Genetics, Cell Biology, Neuroscience Biology

89 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Luk CT, Chan CK, Chiu F, Shi SY, Misra P, Li YZ, Pollock-Tahiri E, Schroer SA, Desai HR, Sivasubramaniyam T, Cai EP, Krishnamurthy M, Han DJ, Chowdhury A, Aslam R, ... ... Woo M, et al. Dual role of caspase 8 in adipocyte apoptosis and metabolic inflammation. Diabetes. PMID 37699387 DOI: 10.2337/db22-1033  0.37
2022 Jiang Z, Li H, Schroer SA, Voisin V, Ju Y, Pacal M, Erdmann N, Shi W, Chung PED, Deng T, Chen NJ, Ciavarra G, Datti A, Mak TW, Harrington L, ... ... Woo M, et al. Hypophosphorylated pRb knock-in mice exhibit hallmarks of aging and vitamin C-preventable diabetes. The Embo Journal. e106825. PMID 35023164 DOI: 10.15252/embj.2020106825  0.366
2020 Zhe Li Y, Di Cristofano A, Woo M. Metabolic Role of PTEN in Insulin Signaling and Resistance. Cold Spring Harbor Perspectives in Medicine. PMID 31964643 DOI: 10.1101/cshperspect.a036137  0.343
2019 Park YJ, Woo M. Pancreatic β cells: Gatekeepers of type 2 diabetes. The Journal of Cell Biology. PMID 30696700 DOI: 10.1083/Jcb.201810097  0.437
2018 Zhao X, Xu Y, Wu Y, Zhang H, Shi H, Zhu H, Woo M, Wu X. Involvement of the STAT5-CyclinD/CDK4-pRb pathway in beta cell proliferation stimulated by prolactin during pregnancy. American Journal of Physiology. Endocrinology and Metabolism. PMID 30512986 DOI: 10.1152/Ajpendo.00242.2018  0.411
2018 Zhang Y, Thai K, Jin T, Woo M, Gilbert RE. SIRT1 activation attenuates α cell hyperplasia, hyperglucagonaemia and hyperglycaemia in STZ-diabetic mice. Scientific Reports. 8: 13972. PMID 30228292 DOI: 10.1038/S41598-018-32351-Z  0.378
2018 Tsai S, Clemente-Casares X, Zhou AC, Lei H, Ahn JJ, Chan YT, Choi O, Luck H, Woo M, Dunn SE, Engleman EG, Watts TH, Winer S, Winer DA. Insulin Receptor-Mediated Stimulation Boosts T Cell Immunity during Inflammation and Infection. Cell Metabolism. PMID 30174303 DOI: 10.1016/J.Cmet.2018.08.003  0.366
2018 Costford SR, Tattoli I, Duan FT, Volchuk A, Klip A, Philpott DJ, Woo M, Girardin SE. Male Mice Lacking NLRX1 Are Partially Protected From High-Fat Diet-Induced Hyperglycemia. Journal of the Endocrine Society. 2: 336-347. PMID 29577109 DOI: 10.1210/Js.2017-00360  0.426
2017 Dodington DW, Desai HR, Woo M. JAK/STAT - Emerging Players in Metabolism. Trends in Endocrinology and Metabolism: Tem. PMID 29191719 DOI: 10.1016/J.Tem.2017.11.001  0.326
2017 Desai HR, Sivasubramaniyam T, Revelo XS, Schroer SA, Luk CT, Rikkala PR, Metherel AH, Dodington DW, Park YJ, Kim MJ, Rapps JA, Besla R, Robbins CS, Wagner KU, Bazinet RP, ... ... Woo M, et al. Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation. Scientific Reports. 7: 7653. PMID 28794431 DOI: 10.1038/S41598-017-07923-0  0.408
2017 Sivasubramaniyam T, Schroer SA, Li A, Luk CT, Shi SY, Besla R, Dodington DW, Metherel AH, Kitson AP, Brunt JJ, Lopes J, Wagner KU, Bazinet RP, Bendeck MP, Robbins CS, ... Woo M, et al. Hepatic JAK2 protects against atherosclerosis through circulating IGF-1. Jci Insight. 2. PMID 28724798 DOI: 10.1172/Jci.Insight.93735  0.314
2017 Ghazarian M, Revelo XS, Nøhr MK, Luck H, Zeng K, Lei H, Tsai S, Schroer SA, Park YJ, Chng MHY, Shen L, D'Angelo JA, Horton P, Chapman WC, Brockmeier D, ... Woo M, et al. Type I Interferon Responses Drive Intrahepatic T cells to Promote Metabolic Syndrome. Science Immunology. 2. PMID 28567448 DOI: 10.1126/Sciimmunol.Aai7616  0.39
2017 Alghamdi TA, Majumder S, Thieme K, Batchu SN, White KE, Liu Y, Brijmohan AS, Bowskill BB, Advani SL, Woo M, Advani A. Janus Kinase 2 Regulates Transcription Factor EB Expression and Autophagy Completion in Glomerular Podocytes. Journal of the American Society of Nephrology : Jasn. PMID 28424277 DOI: 10.1681/Asn.2016111208  0.352
2017 Luk CT, Shi SY, Cai EP, Sivasubramaniyam T, Krishnamurthy M, Brunt JJ, Schroer SA, Winer DA, Woo M. FAK signalling controls insulin sensitivity through regulation of adipocyte survival. Nature Communications. 8: 14360. PMID 28165007 DOI: 10.1038/Ncomms14360  0.417
2017 Shi SY, Schroer SA, Luk CT, Kim MJ, Dodington DW, Lin L, Sivasubramaniyam T, Cai EP, Lu SY, Wagner KU, Bazinet RP, Woo M. Janus kinase 2 (JAK2) Dissociates Hepatosteatosis from Hepatocellular Carcinoma in Mice. The Journal of Biological Chemistry. PMID 28100771 DOI: 10.1074/Jbc.M116.752519  0.329
2016 Revelo XS, Ghazarian M, Chng MH, Luck H, Kim JH, Zeng K, Shi SY, Tsai S, Lei H, Kenkel J, Liu CL, Tangsombatvisit S, Tsui H, Sima C, Xiao C, ... ... Woo M, et al. Nucleic Acid-Targeting Pathways Promote Inflammation in Obesity-Related Insulin Resistance. Cell Reports. PMID 27373163 DOI: 10.1016/J.Celrep.2016.06.024  0.369
2016 Montada-Atin T, Choi D, Woo M, Retnakaran R, Huang M, Prasad GV, Zaltzman JS. Reduction in new-onset diabetes mellitus after renal transplant with erythropoietin-stimulating agents: a retrospective cohort study. Canadian Journal of Kidney Health and Disease. 3: 23. PMID 27119016 DOI: 10.1186/S40697-016-0114-9  0.348
2016 Luk CT, Schroer SA, Woo M. Methods for Assessing the In Vivo Role of PTEN in Glucose Homeostasis. Methods in Molecular Biology (Clifton, N.J.). 1388: 75-91. PMID 27033072 DOI: 10.1007/978-1-4939-3299-3_7  0.476
2016 Luk CT, Shi SY, Krishnamurthy M, Schroer SA, Woo M. Caspase 8 Plays a Pivotal Role in Adipose Tissue Inflammatory Signalling and Glucose HomeostasisImage 9 Canadian Journal of Diabetes. 40: S59. DOI: 10.1016/J.Jcjd.2016.08.166  0.341
2015 Shi SY, Zhang W, Luk CT, Sivasubramaniyam T, Brunt JJ, Schroer SA, Desai HR, Majerski A, Woo M. JAK2 promotes brown adipose tissue function and is required for diet- and cold-induced thermogenesis in mice. Diabetologia. PMID 26515423 DOI: 10.1007/S00125-015-3786-2  0.35
2015 Chang YJ, Pownall S, Jensen TE, Mouaaz S, Foltz W, Zhou L, Liadis N, Woo M, Hao Z, Dutt P, Bilan PJ, Klip A, Mak T, Stambolic V. The Rho-guanine nucleotide exchange factor PDZ-RhoGEF governs susceptibility to diet-induced obesity and type 2 diabetes. Elife. 4. PMID 26512886 DOI: 10.7554/Elife.06011  0.3
2015 Xu Y, Wang X, Gao L, Zhu J, Zhang H, Shi H, Woo M, Wu X. Prolactin-stimulated survivin induction is required for beta cell mass expansion during pregnancy in mice. Diabetologia. PMID 26099856 DOI: 10.1007/S00125-015-3670-0  0.364
2015 Shi SY, Lu SY, Sivasubramaniyam T, Revelo XS, Cai EP, Luk CT, Schroer SA, Patel P, Kim RH, Bombardier E, Quadrilatero J, Tupling AR, Mak TW, Winer DA, Woo M. DJ-1 links muscle ROS production with metabolic reprogramming and systemic energy homeostasis in mice. Nature Communications. 6: 7415. PMID 26077864 DOI: 10.1038/Ncomms8415  0.363
2015 Luck H, Tsai S, Chung J, Clemente-Casares X, Ghazarian M, Revelo XS, Lei H, Luk CT, Shi SY, Surendra A, Copeland JK, Ahn J, Prescott D, Rasmussen BA, Chng MH, ... ... Woo M, et al. Regulation of obesity-related insulin resistance with gut anti-inflammatory agents. Cell Metabolism. 21: 527-42. PMID 25863246 DOI: 10.1016/J.Cmet.2015.03.001  0.366
2015 Gilbert RE, Thai K, Advani SL, Cummins CL, Kepecs DM, Schroer SA, Woo M, Zhang Y. SIRT1 activation ameliorates hyperglycaemia by inducing a torpor-like state in an obese mouse model of type 2 diabetes. Diabetologia. 58: 819-27. PMID 25563725 DOI: 10.1007/S00125-014-3485-4  0.385
2015 Shah R, Ye C, Woo M, Connelly PW, Hanley AJ, Sermer M, Zinman B, Retnakaran R. Erythropoietin and glucose homeostasis in women at varying degrees of future diabetic risk. Journal of Diabetes and Its Complications. 29: 26-31. PMID 25440262 DOI: 10.1016/J.Jdiacomp.2014.09.005  0.354
2015 Wang L, Luk CT, Cai EP, Schroer SA, Allister EM, Shi SY, Wheeler MB, Gaisano HY, Woo M. PTEN deletion in pancreatic α-cells protects against high-fat diet-induced hyperglucagonemia and insulin resistance. Diabetes. 64: 147-57. PMID 25092678 DOI: 10.2337/Db13-1715  0.61
2015 Revelo XS, Tsai S, Lei H, Luck H, Ghazarian M, Tsui H, Shi SY, Schroer S, Luk CT, Lin GH, Mak TW, Woo M, Winer S, Winer DA. Perforin is a novel immune regulator of obesity-related insulin resistance. Diabetes. 64: 90-103. PMID 25048196 DOI: 10.2337/Db13-1524  0.424
2015 Chang Y, Pownall S, Jensen TE, Mouaaz S, Foltz W, Zhou L, Liadis N, Woo M, Hao Z, Dutt P, Bilan PJ, Klip A, Mak T, Stambolic V. Author response: The Rho-guanine nucleotide exchange factor PDZ-RhoGEF governs susceptibility to diet-induced obesity and type 2 diabetes Elife. DOI: 10.7554/Elife.06011.030  0.33
2014 Brunt JJ, Shi SY, Schroer SA, Sivasubramaniyam T, Cai EP, Woo M. Overexpression of HIF-2α in pancreatic β cells does not alter glucose homeostasis. Islets. 6: e1006075. PMID 25833250 DOI: 10.1080/19382014.2015.1006075  0.419
2014 Cai EP, Luk CT, Wu X, Schroer SA, Shi SY, Sivasubramaniyam T, Brunt JJ, Zacksenhaus E, Woo M. Rb and p107 are required for alpha cell survival, beta cell cycle control and glucagon-like peptide-1 action. Diabetologia. 57: 2555-65. PMID 25249236 DOI: 10.1007/S00125-014-3381-Y  0.369
2014 Wang L, Luk CT, Schroer SA, Smith AM, Li X, Cai EP, Gaisano H, MacDonald PE, Hao Z, Mak TW, Woo M. Dichotomous role of pancreatic HUWE1/MULE/ARF-BP1 in modulating beta cell apoptosis in mice under physiological and genotoxic conditions. Diabetologia. 57: 1889-98. PMID 24981769 DOI: 10.1007/S00125-014-3295-8  0.598
2014 Woo M, Hawkins M. Beyond erythropoiesis: emerging metabolic roles of erythropoietin. Diabetes. 63: 2229-31. PMID 24962925 DOI: 10.2337/Db14-0566  0.399
2014 Costford SR, Castro-Alves J, Chan KL, Bailey LJ, Woo M, Belsham DD, Brumell JH, Klip A. Mice lacking NOX2 are hyperphagic and store fat preferentially in the liver. American Journal of Physiology. Endocrinology and Metabolism. 306: E1341-53. PMID 24760992 DOI: 10.1152/Ajpendo.00089.2014  0.402
2014 Wang L, Opland D, Tsai S, Luk CT, Schroer SA, Allison MB, Elia AJ, Furlonger C, Suzuki A, Paige CJ, Mak TW, Winer DA, Myers MG, Woo M. Pten deletion in RIP-Cre neurons protects against type 2 diabetes by activating the anti-inflammatory reflex. Nature Medicine. 20: 484-92. PMID 24747746 DOI: 10.1038/Nm.3527  0.572
2014 Cai EP, Wu X, Zacksenhaus E, Woo M. Timing is everything: Rb's choice in islet-cell fate. Cell Cycle (Georgetown, Tex.). 13: 873-4. PMID 24552825 DOI: 10.4161/Cc.28198  0.446
2014 Shi SY, Luk CT, Brunt JJ, Sivasubramaniyam T, Lu SY, Schroer SA, Woo M. Adipocyte-specific deficiency of Janus kinase (JAK) 2 in mice impairs lipolysis and increases body weight, and leads to insulin resistance with ageing Diabetologia. 57: 1016-1026. PMID 24531222 DOI: 10.1007/S00125-014-3185-0  0.383
2014 Park YJ, Woo M, Kieffer TJ, Hakem R, Safikhan N, Yang F, Ao Z, Warnock GL, Marzban L. The role of caspase-8 in amyloid-induced beta cell death in human and mouse islets. Diabetologia. 57: 765-75. PMID 24442508 DOI: 10.1007/S00125-013-3152-1  0.431
2013 Cai EP, Wu X, Schroer SA, Elia AJ, Nostro MC, Zacksenhaus E, Woo M. Retinoblastoma tumor suppressor protein in pancreatic progenitors controls α- and β-cell fate. Proceedings of the National Academy of Sciences of the United States of America. 110: 14723-8. PMID 23946427 DOI: 10.1073/Pnas.1303386110  0.414
2013 Luk CT, Shi SY, Choi D, Cai EP, Schroer SA, Woo M. In vivo knockdown of adipocyte erythropoietin receptor does not alter glucose or energy homeostasis Endocrinology. 154: 3652-3659. PMID 23885016 DOI: 10.1210/En.2013-1113  0.406
2013 Shi SY, Luk CT, Brunt JJ, Schroer SA, Wagner K, Woo M. Adipocyte-Specific Deletion of Janus Kinase 2 (JAK2) Leads to Increased Adiposity and Age-Related Glucose Intolerance Canadian Journal of Diabetes. 37: S66. DOI: 10.1016/J.Jcjd.2013.08.200  0.444
2013 Shi SY, Lu S, Sivasubramaniyam T, Cai EP, Schroer SA, Kim RH, Mak TW, Woo M. Absence of the ROS Scavenger DJ-1 Paradoxically Protects Mice from Obesity and Insulin Resistance Canadian Journal of Diabetes. 37: S66. DOI: 10.1016/J.Jcjd.2013.08.199  0.445
2013 Luk CT, Shi SY, Schroer SA, Woo M. Disruption of Adipocyte Caspase 8 Protects Mice from Weight Gain and Glucose Intolerance Canadian Journal of Diabetes. 37: S65-S66. DOI: 10.1016/J.Jcjd.2013.08.198  0.356
2013 Luk CT, Shi SY, Cai EP, Sivasubramaniyam T, Schroer SA, Woo M. Adipocyte-Specific FAK Deletion in Mice Leads to Insulin Resistance but Divergent Adipose Tissue Remodelling Under Lean and Obese Conditions Canadian Journal of Diabetes. 37: S8-S9. DOI: 10.1016/J.Jcjd.2013.08.021  0.357
2012 Wu X, Zhang Q, Wang X, Zhu J, Xu K, Okada H, Wang R, Woo M. Survivin is required for beta-cell mass expansion in the pancreatic duct-ligated mouse model. Plos One. 7: e41976. PMID 22870272 DOI: 10.1371/Journal.Pone.0041976  0.364
2012 Zhu D, Zhang Y, Lam PP, Dolai S, Liu Y, Cai EP, Choi D, Schroer SA, Kang Y, Allister EM, Qin T, Wheeler MB, Wang CC, Hong WJ, Woo M, et al. Dual role of VAMP8 in regulating insulin exocytosis and islet β cell growth. Cell Metabolism. 16: 238-49. PMID 22841572 DOI: 10.1016/J.Cmet.2012.07.001  0.451
2012 Cai EP, Casimir M, Schroer SA, Luk CT, Shi SY, Choi D, Dai XQ, Hajmrle C, Spigelman AF, Zhu D, Gaisano HY, MacDonald PE, Woo M. In vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule trafficking. Diabetes. 61: 1708-18. PMID 22498697 DOI: 10.2337/Db11-1344  0.436
2012 Park YJ, Lee S, Kieffer TJ, Warnock GL, Safikhan N, Speck M, Hao Z, Woo M, Marzban L. Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide. Diabetologia. PMID 22301943 DOI: 10.1007/S00125-012-2451-2  0.436
2012 Shi SY, Martin RG, Duncan RE, Choi D, Lu SY, Schroer SA, Cai EP, Luk CT, Hopperton KE, Domenichiello AF, Tang C, Naples M, Dekker MJ, Giacca A, Adeli K, ... ... Woo M, et al. Hepatocyte-specific deletion of Janus kinase 2 (JAK2) protects against diet-induced steatohepatitis and glucose intolerance. The Journal of Biological Chemistry. 287: 10277-88. PMID 22275361 DOI: 10.1074/Jbc.M111.317453  0.413
2012 Liu Y, Zhang Y, Zhu D, Cai EP, Choi D, Schroer SA, Lam PP, Kang Y, Woo M, Gaisano HY. VAMP8 Deletion Delays the Onset of Streptozotocin-Induced Hyperglycemia Canadian Journal of Diabetes. 36: 251-256. DOI: 10.1016/J.Jcjd.2012.07.469  0.455
2012 Park YJ, Woo M, Ao Z, Kieffer TJ, Warnock GL, Marzban L. Deletion of Caspase-8 Protects Islet β-Cells from Cytotoxic Effects of Human Islet Amyloid Polypeptide Aggregates Canadian Journal of Diabetes. 36: S18. DOI: 10.1016/J.Jcjd.2012.07.075  0.371
2011 Choi D, Cai EP, Woo M. The redundant role of JAK2 in regulating pancreatic β-cell mass. Islets. 3: 389-92. PMID 22045263 DOI: 10.4161/Isl.3.6.18158  0.442
2011 Choi D, Cai EP, Woo M. The redundant role of JAK2 in regulating pancreatic β-cell mass. Islets. 3. PMID 22008414  0.339
2011 Choi D, Schroer SA, Lu SY, Cai EP, Hao Z, Woo M. Redundant role of the cytochrome c-mediated intrinsic apoptotic pathway in pancreatic β-cells. The Journal of Endocrinology. 210: 285-92. PMID 21719578 DOI: 10.1530/Joe-11-0073  0.412
2011 Choi D, Retnakaran R, Woo M. The extra-hematopoietic role of erythropoietin in diabetes mellitus. Current Diabetes Reviews. 7: 284-90. PMID 21644916 DOI: 10.2174/157339911796397820  0.415
2011 Li L, Hossain MA, Sadat S, Hager L, Liu L, Tam L, Schroer S, Huogen L, Fantus IG, Connelly PW, Woo M, Ng DS. Lecithin cholesterol acyltransferase null mice are protected from diet-induced obesity and insulin resistance in a gender-specific manner through multiple pathways. The Journal of Biological Chemistry. 286: 17809-20. PMID 21454561 DOI: 10.1074/Jbc.M110.180893  0.402
2011 Choi D, Cai EP, Schroer SA, Wang L, Woo M. Vhl is required for normal pancreatic β cell function and the maintenance of β cell mass with age in mice. Laboratory Investigation; a Journal of Technical Methods and Pathology. 91: 527-38. PMID 21242957 DOI: 10.1038/Labinvest.2010.207  0.599
2010 Choi D, Schroer SA, Lu SY, Wang L, Wu X, Liu Y, Zhang Y, Gaisano HY, Wagner KU, Wu H, Retnakaran R, Woo M. Erythropoietin protects against diabetes through direct effects on pancreatic beta cells. The Journal of Experimental Medicine. 207: 2831-42. PMID 21149549 DOI: 10.1084/Jem.20100665  0.596
2010 Murakami K, Liadis N, Sarmiento J, Elford AR, Woo M, Nguyen LT, Mak TW, Ohashi PS. Caspase 3 is not essential for the induction of anergy or multiple pathways of CD8+ T-cell death. European Journal of Immunology. 40: 3372-7. PMID 21110320 DOI: 10.1002/Eji.201040475  0.323
2010 Wang L, Liu Y, Yan Lu S, Nguyen KT, Schroer SA, Suzuki A, Mak TW, Gaisano H, Woo M. Deletion of Pten in pancreatic ß-cells protects against deficient ß-cell mass and function in mouse models of type 2 diabetes. Diabetes. 59: 3117-26. PMID 20852026 DOI: 10.2337/Db09-1805  0.612
2010 Law E, Lu S, Kieffer TJ, Warnock GL, Ao Z, Woo M, Marzban L. Differences between amyloid toxicity in alpha and beta cells in human and mouse islets and the role of caspase-3. Diabetologia. 53: 1415-27. PMID 20369225 DOI: 10.1007/S00125-010-1717-9  0.41
2010 Choi D, Woo M. Executioners of apoptosis in pancreatic {beta}-cells: not just for cell death. American Journal of Physiology. Endocrinology and Metabolism. 298: E735-41. PMID 20028968 DOI: 10.1152/Ajpendo.00696.2009  0.444
2009 Choi D, Radziszewska A, Schroer SA, Liadis N, Liu Y, Zhang Y, Lam PP, Sheu L, Hao Z, Gaisano HY, Woo M. Deletion of Fas in the pancreatic beta-cells leads to enhanced insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. 297: E1304-12. PMID 19755672 DOI: 10.1152/Ajpendo.00217.2009  0.477
2009 Wu X, Wang L, Schroer S, Choi D, Chen P, Okada H, Woo M. Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice. Diabetologia. 52: 2130-41. PMID 19644667 DOI: 10.1007/S00125-009-1469-6  0.537
2009 Pigeau GM, Kolic J, Ball BJ, Hoppa MB, Wang YW, Rückle T, Woo M, Manning Fox JE, MacDonald PE. Insulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cells. Diabetes. 58: 2084-92. PMID 19549714 DOI: 10.2337/Db08-1371  0.395
2009 Plant PJ, Bain JR, Correa JE, Woo M, Batt J. Absence of caspase-3 protects against denervation-induced skeletal muscle atrophy. Journal of Applied Physiology (Bethesda, Md. : 1985). 107: 224-34. PMID 19390003 DOI: 10.1152/Japplphysiol.90932.2008  0.341
2009 Radziszewska A, Schroer SA, Choi D, Tajmir P, Radulovich N, Ho JC, Wang L, Liadis N, Hakem R, Tsao MS, Penn LZ, Evan GI, Woo M. Absence of caspase-3 protects pancreatic {beta}-cells from c-Myc-induced apoptosis without leading to tumor formation. The Journal of Biological Chemistry. 284: 10947-56. PMID 19213729 DOI: 10.1074/Jbc.M806960200  0.577
2009 Radziszewska A, Choi D, Nguyen KT, Schroer SA, Tajmir P, Wang L, Suzuki A, Mak TW, Evan GI, Woo M. PTEN deletion and concomitant c-Myc activation do not lead to tumor formation in pancreatic beta cells. The Journal of Biological Chemistry. 284: 2917-22. PMID 19056726 DOI: 10.1074/Jbc.M805183200  0.574
2009 Kanungo AK, Liadis N, Robertson J, Woo M, Henderson JT. Excitatory tonus is required for the survival of granule cell precursors during postnatal development within the cerebellum. Neuroscience. 158: 1364-1377. PMID 19056468 DOI: 10.1016/J.Neuroscience.2008.10.062  0.308
2008 Janzen V, Fleming HE, Riedt T, Karlsson G, Riese MJ, Lo Celso C, Reynolds G, Milne CD, Paige CJ, Karlsson S, Woo M, Scadden DT. Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3. Cell Stem Cell. 2: 584-94. PMID 18522851 DOI: 10.1016/J.Stem.2008.03.012  0.374
2008 Choi D, Nguyen KT, Wang L, Schroer SA, Suzuki A, Mak TW, Woo M. Partial deletion of Pten in the hypothalamus leads to growth defects that cannot be rescued by exogenous growth hormone. Endocrinology. 149: 4382-6. PMID 18499759 DOI: 10.1210/En.2007-1761  0.546
2008 Wu X, Wang L, Chen P, Okada H, Woo M. The Potentially Role of Survivin in Pancrcalic Islet Development and Function. Canadian Journal of Diabetes. 32: 339. DOI: 10.1016/S1499-2671(08)24157-2  0.502
2008 Choi D, Radziszewska A, Schroer SA, Liades N, Woo M. The Essential In Vivo Role of Fas in Pancreatic β Cells Canadian Journal of Diabetes. 32: 335. DOI: 10.1016/S1499-2671(08)24141-9  0.381
2008 WANG L, NGUYEN K, CHOI D, SCHROER S, WOO M. PTEN Deletion in Pancreatic Beta Cells andHypothalamus Protects Against the Development of High Fat Induced Type 2 Diabetes in Mice. Canadian Journal of Diabetes. 32: 304. DOI: 10.1016/S1499-2671(08)24025-6  0.561
2008 Li H, Khosrow-Khavar F, Speck M, Kieffer T, Woo M, Marzban L. Suppression of Caspase-3 Activation Protects Primary Islet β-Cells from the Cytotoxic Effects of Human Islet Amyloid Polypeptide. Canadian Journal of Diabetes. 32: 302. DOI: 10.1016/S1499-2671(08)24016-5  0.387
2007 Liadis N, Salmena L, Kwan E, Tajmir P, Schroer SA, Radziszewska A, Li X, Sheu L, Eweida M, Xu S, Gaisano HY, Hakem R, Woo M. Distinct in vivo roles of caspase-8 in beta-cells in physiological and diabetes models. Diabetes. 56: 2302-11. PMID 17563067 DOI: 10.2337/Db06-1771  0.503
2006 Nguyen KT, Tajmir P, Lin CH, Liadis N, Zhu XD, Eweida M, Tolasa-Karaman G, Cai F, Wang R, Kitamura T, Belsham DD, Wheeler MB, Suzuki A, Mak TW, Woo M. Essential role of Pten in body size determination and pancreatic beta-cell homeostasis in vivo. Molecular and Cellular Biology. 26: 4511-8. PMID 16738317 DOI: 10.1128/Mcb.00238-06  0.445
2005 Liadis N, Murakami K, Eweida M, Elford AR, Sheu L, Gaisano HY, Hakem R, Ohashi PS, Woo M. Caspase-3-dependent beta-cell apoptosis in the initiation of autoimmune diabetes mellitus. Molecular and Cellular Biology. 25: 3620-9. PMID 15831467 DOI: 10.1128/Mcb.25.9.3620-3629.2005  0.472
2005 Wijesekara N, Konrad D, Eweida M, Jefferies C, Liadis N, Giacca A, Crackower M, Suzuki A, Mak TW, Kahn CR, Klip A, Woo M. Muscle-specific Pten deletion protects against insulin resistance and diabetes. Molecular and Cellular Biology. 25: 1135-45. PMID 15657439 DOI: 10.1128/Mcb.25.3.1135-1145.2005  0.404
2004 Sabbagh L, Kaech SM, Bourbonnière M, Woo M, Cohen LY, Haddad EK, Labrecque N, Ahmed R, Sékaly RP. The selective increase in caspase-3 expression in effector but not memory T cells allows susceptibility to apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 173: 5425-33. PMID 15494489 DOI: 10.4049/Jimmunol.173.9.5425  0.356
2004 Okuyama R, Nguyen BC, Talora C, Ogawa E, Tommasi di Vignano A, Lioumi M, Chiorino G, Tagami H, Woo M, Dotto GP. High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism. Developmental Cell. 6: 551-62. PMID 15068794 DOI: 10.1016/S1534-5807(04)00098-X  0.334
2003 Woo M, Hakem R, Furlonger C, Hakem A, Duncan GS, Sasaki T, Bouchard D, Lu L, Wu GE, Paige CJ, Mak TW. Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity. Nature Immunology. 4: 1016-22. PMID 12970760 DOI: 10.1038/Ni976  0.396
2003 Chen L, Woo M, Hakem R, Miller RG. Perforin-dependent activation-induced cell death acts through caspase 3 but not through caspases 8 or 9. European Journal of Immunology. 33: 769-78. PMID 12616497 DOI: 10.1002/Eji.200323783  0.359
2002 Okada H, Suh WK, Jin J, Woo M, Du C, Elia A, Duncan GS, Wakeham A, Itie A, Lowe SW, Wang X, Mak TW. Generation and characterization of Smac/DIABLO-deficient mice. Molecular and Cellular Biology. 22: 3509-17. PMID 11971981 DOI: 10.1128/Mcb.22.10.3509-3517.2002  0.409
2001 Woo M, Hakem R, Mak TW. Executionary pathway for apoptosis: lessons from mutant mice. Cell Research. 10: 267-78. PMID 11191349 DOI: 10.1038/Sj.Cr.7290054  0.373
1999 Yeh W, Hakem R, Woo M, Mak TW. Gene targeting in the analysis of mammalian apoptosis and TNF receptor superfamily signaling. Immunological Reviews. 169: 283-302. PMID 10450525 DOI: 10.1111/J.1600-065X.1999.Tb01323.X  0.38
1998 Hakem R, Hakem A, Duncan GS, Henderson JT, Woo M, Soengas MS, Elia A, de la Pompa JL, Kagi D, Khoo W, Potter J, Yoshida R, Kaufman SA, Lowe SW, Penninger JM, et al. Differential requirement for caspase 9 in apoptotic pathways in vivo. Cell. 94: 339-52. PMID 9708736 DOI: 10.1016/S0092-8674(00)81477-4  0.366
1998 Woo M, Hakem R, Soengas MS, Duncan GS, Shahinian A, Kägi D, Hakem A, McCurrach M, Khoo W, Kaufman SA, Senaldi G, Howard T, Lowe SW, Mak TW. Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes. Genes & Development. 12: 806-19. PMID 9512515 DOI: 10.1101/Gad.12.6.806  0.378
1996 Hakem R, de la Pompa JL, Sirard C, Mo R, Woo M, Hakem A, Wakeham A, Potter J, Reitmair A, Billia F, Firpo E, Hui CC, Roberts J, Rossant J, Mak TW. The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse. Cell. 85: 1009-23. PMID 8674108 DOI: 10.1016/S0092-8674(00)81302-1  0.321
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