| Year |
Citation |
Score |
| 2023 |
Chourey S, Wang R, Ye Q, Reddy CN, Sun S, Takenaka N, Powell WS, Rokach J. Concise Syntheses of Microsomal Metabolites of a Potent OXE (Oxoeicosanoid) Receptor Antagonist. Chemical & Pharmaceutical Bulletin. 71: 534-544. PMID 37394602 DOI: 10.1248/cpb.c22-00926 |
0.637 |
|
| 2022 |
Cossette C, Chourey S, Ye Q, Reddy CN, Wang R, Poulet S, Slobodchikova I, Vuckovic D, Rokach J, Powell WS. Metabolism of anti-inflammatory OXE (oxoeicosanoid) receptor antagonists by nonhuman primates. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 106144. PMID 35158054 DOI: 10.1016/j.ejps.2022.106144 |
0.613 |
|
| 2021 |
Cossette C, Miller LA, Ye Q, Chourey S, Reddy CN, Rokach J, Powell WS. Targeting the oxoeicosanoid (OXE) receptor with a selective antagonist inhibits allergen-induced pulmonary inflammation in non-human primates. British Journal of Pharmacology. PMID 34766334 DOI: 10.1111/bph.15721 |
0.609 |
|
| 2020 |
Powell WS, Rokach J. Targeting the OXE receptor as a potential novel therapy for asthma. Biochemical Pharmacology. 113930. PMID 32240653 DOI: 10.1016/J.Bcp.2020.113930 |
0.455 |
|
| 2019 |
Ye Q, Chourey S, Reddy CN, Wang R, Cossette C, Gravel S, Slobodchikova I, Vuckovic D, Rokach J, Powell WS. Novel highly potent OXE receptor antagonists with prolonged plasma lifetimes that are converted to active metabolites in vivo in monkeys. British Journal of Pharmacology. PMID 31655025 DOI: 10.1111/Bph.14874 |
0.646 |
|
| 2019 |
Miller LA, Cossette C, Chourey S, Ye Q, Reddy CN, Rokach J, Powell WS. Inhibition of allergen-induced dermal eosinophilia by an oxoeicosanoid (OXE) receptor antagonist in nonhuman primates. British Journal of Pharmacology. PMID 31655023 DOI: 10.1111/Bph.14872 |
0.644 |
|
| 2018 |
Chourey S, Ye Q, Reddy CN, Wang R, Cossette C, Gravel S, Slobodchikova I, Vuckovic D, Rokach J, Powell WS. Novel highly potent and metabolically resistant oxoeicosanoid (OXE) receptor antagonists that block the actions of the granulocyte chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE). Journal of Medicinal Chemistry. PMID 29972644 DOI: 10.1021/Acs.Jmedchem.8B00154 |
0.662 |
|
| 2018 |
Chourey S, Ye Q, Reddy CN, Cossette C, Gravel S, Zeller M, Slobodchikova I, Vuckovic D, Rokach J, Powell WS. Corrigendum to "In vivo α-hydroxylation of a 2-alkylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid in monkeys" [Biochem. Pharmacol. 138 (2017) 107-118]. Biochemical Pharmacology. 154: 174. PMID 29754018 DOI: 10.1016/J.Bcp.2018.04.025 |
0.637 |
|
| 2018 |
Reddy CN, Alhamza H, Chourey S, Ye Q, Gore V, Cossette C, Gravel S, Slobodchikova I, Vuckovic D, Rokach J, Powell WS. Metabolism and pharmacokinetics of a potent N-acylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) in rats and monkeys. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 29339225 DOI: 10.1016/J.Ejps.2018.01.021 |
0.764 |
|
| 2017 |
Ye Q, Chourey S, Wang R, Chintam NR, Gravel S, Powell WS, Rokach J. Structure-activity relationship study of β-oxidation resistant indole-based 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) receptor antagonists. Bioorganic & Medicinal Chemistry Letters. PMID 28943042 DOI: 10.1016/J.Bmcl.2017.08.034 |
0.673 |
|
| 2017 |
Chourey S, Ye Q, Reddy CN, Cossette C, Gravel S, Zeller M, Slobodchikova I, Vuckovic D, Rokach J, Powell WS. In vivo α-hydroxylation of a 2-alkylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid in monkeys. Biochemical Pharmacology. PMID 28476332 DOI: 10.1016/J.Bcp.2017.04.031 |
0.649 |
|
| 2017 |
Nagendra Reddy C, Ye Q, Patel P, Sivendran S, Chourey S, Wang R, Anumolu JR, Grant GE, Powell WS, Rokach J. Design and synthesis of affinity chromatography ligands for the purification of 5-hydroxyeicosanoid dehydrogenase. Bioorganic & Medicinal Chemistry. 25: 116-125. PMID 28340986 DOI: 10.1016/J.Bmc.2016.10.017 |
0.799 |
|
| 2016 |
Cossette C, Chourey S, Ye Q, Nagendra Reddy C, Gore V, Gravel S, Slobodchikova I, Vuckovic D, Rokach J, Powell WS. Pharmacokinetics and metabolism of selective oxoeicosanoid (OXE) receptor antagonists and their effects on 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE)-induced granulocyte activation in monkeys. Journal of Medicinal Chemistry. PMID 27766872 DOI: 10.1021/Acs.Jmedchem.6B00895 |
0.769 |
|
| 2015 |
Cossette C, Gravel S, Reddy CN, Gore V, Chourey S, Ye Q, Snyder NW, Mesaros CA, Blair IA, Lavoie JP, Reinero CR, Rokach J, Powell WS. Biosynthesis and actions of 5-oxoeicosatetraenoic acid (5-oxo-ETE) on feline granulocytes. Biochemical Pharmacology. 96: 247-55. PMID 26032638 DOI: 10.1016/J.Bcp.2015.05.009 |
0.761 |
|
| 2015 |
Powell WS, Rokach J. Biosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acid. Biochimica Et Biophysica Acta. 1851: 340-55. PMID 25449650 DOI: 10.1016/J.Bbalip.2014.10.008 |
0.449 |
|
| 2015 |
Nagendra Reddy C, Ye Q, Chourey S, Gravel S, Powell WS, Rokach J. Stereoselective synthesis of two highly potent 5-oxo-ETE receptor antagonists Tetrahedron Letters. 56: 6896-6899. DOI: 10.1016/J.Tetlet.2015.10.097 |
0.667 |
|
| 2014 |
Patel P, Reddy CN, Gore V, Chourey S, Ye Q, Ouedraogo YP, Gravel S, Powell WS, Rokach J. Two Potent OXE-R Antagonists: Assignment of Stereochemistry. Acs Medicinal Chemistry Letters. 5: 815-9. PMID 25050171 DOI: 10.1021/Ml500161V |
0.811 |
|
| 2014 |
Gore V, Chourey S, Ye Q, Patel P, Ouedraogo Y, Gravel S, Powell WS, Rokach J. Base-dependent formation of cis and trans olefins and their application in the synthesis of 5-oxo-ETE receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 24: 3385-8. PMID 24948567 DOI: 10.1016/J.Bmcl.2014.05.090 |
0.781 |
|
| 2014 |
Gore V, Gravel S, Cossette C, Patel P, Chourey S, Ye Q, Rokach J, Powell WS. Inhibition of 5-oxo-6,8,11,14-eicosatetraenoic acid-induced activation of neutrophils and eosinophils by novel indole OXE receptor antagonists. Journal of Medicinal Chemistry. 57: 364-77. PMID 24351031 DOI: 10.1021/Jm401292M |
0.793 |
|
| 2013 |
Powell WS, Rokach J. The eosinophil chemoattractant 5-oxo-ETE and the OXE receptor. Progress in Lipid Research. 52: 651-65. PMID 24056189 DOI: 10.1016/J.Plipres.2013.09.001 |
0.415 |
|
| 2013 |
Gore V, Patel P, Chang CT, Sivendran S, Kang N, Ouedraogo YP, Gravel S, Powell WS, Rokach J. 5-Oxo-ETE receptor antagonists. Journal of Medicinal Chemistry. 56: 3725-32. PMID 23581530 DOI: 10.1021/Jm400480J |
0.759 |
|
| 2011 |
Grant GE, Rubino S, Gravel S, Wang X, Patel P, Rokach J, Powell WS. Enhanced formation of 5-oxo-6,8,11,14-eicosatetraenoic acid by cancer cells in response to oxidative stress, docosahexaenoic acid and neutrophil-derived 5-hydroxy-6,8,11,14-eicosatetraenoic acid. Carcinogenesis. 32: 822-8. PMID 21393477 DOI: 10.1093/Carcin/Bgr044 |
0.571 |
|
| 2011 |
Patel P, Gore V, Powell WS, Rokach J. C20-trifluoro-5-oxo-ETE: a metabolically stable 5-oxo-ETE derivative. Bioorganic & Medicinal Chemistry Letters. 21: 1987-90. PMID 21377873 DOI: 10.1016/J.Bmcl.2011.02.021 |
0.724 |
|
| 2011 |
Grant GE, Gravel S, Guay J, Patel P, Mazer BD, Rokach J, Powell WS. 5-oxo-ETE is a major oxidative stress-induced arachidonate metabolite in B lymphocytes. Free Radical Biology & Medicine. 50: 1297-304. PMID 21334434 DOI: 10.1016/J.Freeradbiomed.2011.02.010 |
0.581 |
|
| 2011 |
Patel P, Anumolu JR, Powell WS, Rokach J. 5-oxo-15-HETE: total synthesis and bioactivity. Bioorganic & Medicinal Chemistry Letters. 21: 1857-60. PMID 21316960 DOI: 10.1016/J.Bmcl.2011.01.032 |
0.559 |
|
| 2009 |
Chang CT, Patel P, Gore V, Song WL, Lawson JA, Powell WS, Fitzgerald GA, Rokach J. A new approach to the synthesis of polyunsaturated deuterated isoprostanes: total synthesis of d4-5-epi-8,12-iso-iPF3alpha-VI and d4-8,12-iso-iPF3alpha-VI. Bioorganic & Medicinal Chemistry Letters. 19: 6755-8. PMID 19846297 DOI: 10.1016/J.Bmcl.2009.09.099 |
0.776 |
|
| 2009 |
Song WL, Paschos G, Fries S, Reilly MP, Yu Y, Rokach J, Chang CT, Patel P, Lawson JA, Fitzgerald GA. Novel eicosapentaenoic acid-derived F3-isoprostanes as biomarkers of lipid peroxidation. The Journal of Biological Chemistry. 284: 23636-43. PMID 19520854 DOI: 10.1074/Jbc.M109.024075 |
0.656 |
|
| 2009 |
Grant GE, Rokach J, Powell WS. 5-Oxo-ETE and the OXE receptor. Prostaglandins & Other Lipid Mediators. 89: 98-104. PMID 19450703 DOI: 10.1016/J.Prostaglandins.2009.05.002 |
0.406 |
|
| 2009 |
Graham FD, Erlemann KR, Gravel S, Rokach J, Powell WS. Oxidative stress-induced changes in pyridine nucleotides and chemoattractant 5-lipoxygenase products in aging neutrophils. Free Radical Biology & Medicine. 47: 62-71. PMID 19376220 DOI: 10.1016/J.Freeradbiomed.2009.04.016 |
0.372 |
|
| 2009 |
Patel P, Cossette C, Anumolu JR, Erlemann KR, Grant GE, Rokach J, Powell WS. Substrate selectivity of 5-hydroxyeicosanoid dehydrogenase and its inhibition by 5-hydroxy-Delta6-long-chain fatty acids. The Journal of Pharmacology and Experimental Therapeutics. 329: 335-41. PMID 19164464 DOI: 10.1124/Jpet.108.143453 |
0.62 |
|
| 2008 |
Chang CT, Patel P, Kang N, Lawson JA, Song WL, Powell WS, FitzGerald GA, Rokach J. Eicosapentaenoic-acid-derived isoprostanes: synthesis and discovery of two major isoprostanes. Bioorganic & Medicinal Chemistry Letters. 18: 5523-7. PMID 18804370 DOI: 10.1016/J.Bmcl.2008.09.008 |
0.74 |
|
| 2008 |
Patel P, Lee GJ, Kim S, Grant GE, Powell WS, Rokach J. Enantio- and stereospecific syntheses of 15(R)-Me-PGD2, a potent and selective DP2-receptor agonist. The Journal of Organic Chemistry. 73: 7213-8. PMID 18700746 DOI: 10.1021/Jo801190M |
0.646 |
|
| 2008 |
Patel P, Cossette C, Anumolu JR, Gravel S, Lesimple A, Mamer OA, Rokach J, Powell WS. Structural requirements for activation of the 5-oxo-6E,8Z, 11Z,14Z-eicosatetraenoic acid (5-oxo-ETE) receptor: identification of a mead acid metabolite with potent agonist activity. The Journal of Pharmacology and Experimental Therapeutics. 325: 698-707. PMID 18292294 DOI: 10.1124/Jpet.107.134908 |
0.618 |
|
| 2008 |
Cossette C, Patel P, Anumolu JR, Sivendran S, Lee GJ, Gravel S, Graham FD, Lesimple A, Mamer OA, Rokach J, Powell WS. Human neutrophils convert the sebum-derived polyunsaturated fatty acid Sebaleic acid to a potent granulocyte chemoattractant. The Journal of Biological Chemistry. 283: 11234-43. PMID 18287092 DOI: 10.1074/Jbc.M709531200 |
0.78 |
|
| 2008 |
Song WL, Lawson JA, Reilly D, Rokach J, Chang CT, Giasson B, FitzGerald GA. Neurofurans, novel indices of oxidant stress derived from docosahexaenoic acid. The Journal of Biological Chemistry. 283: 6-16. PMID 17921521 DOI: 10.1074/Jbc.M706124200 |
0.586 |
|
| 2007 |
Patel P, Chang CT, Kang N, Lee GJ, Powell WS, Rokach J. Reductive Deprotection of Silyl Groups with Wilkinson's Catalyst/Catechol Borane. Tetrahedron Letters. 48: 5289-5292. PMID 18037973 DOI: 10.1016/J.Tetlet.2007.05.118 |
0.711 |
|
| 2007 |
Erlemann KR, Cossette C, Gravel S, Lesimple A, Lee GJ, Saha G, Rokach J, Powell WS. Airway epithelial cells synthesize the lipid mediator 5-oxo-ETE in response to oxidative stress. Free Radical Biology & Medicine. 42: 654-64. PMID 17291989 DOI: 10.1016/J.Freeradbiomed.2006.12.006 |
0.412 |
|
| 2007 |
Erlemann KR, Cossette C, Grant GE, Lee GJ, Patel P, Rokach J, Powell WS. Regulation of 5-hydroxyeicosanoid dehydrogenase activity in monocytic cells. The Biochemical Journal. 403: 157-65. PMID 17166093 DOI: 10.1042/Bj20061617 |
0.561 |
|
| 2007 |
Cossette C, Walsh SE, Kim S, Lee GJ, Lawson JA, Bellone S, Rokach J, Powell WS. Agonist and antagonist effects of 15R-prostaglandin (PG) D2 and 11-methylene-PGD2 on human eosinophils and basophils. The Journal of Pharmacology and Experimental Therapeutics. 320: 173-9. PMID 17041009 DOI: 10.1124/Jpet.106.111062 |
0.537 |
|
| 2006 |
Erlemann KR, Cossette C, Gravel S, Stamatiou PB, Lee GJ, Rokach J, Powell WS. Metabolism of 5-hydroxy-6,8,11,14-eicosatetraenoic acid by human endothelial cells. Biochemical and Biophysical Research Communications. 350: 151-6. PMID 16997273 DOI: 10.1016/J.Bbrc.2006.09.011 |
0.411 |
|
| 2006 |
Lawson JA, Kim S, Powell WS, FitzGerald GA, Rokach J. Oxidized derivatives of omega-3 fatty acids: identification of IPF3 alpha-VI in human urine. Journal of Lipid Research. 47: 2515-24. PMID 16943517 DOI: 10.1194/Jlr.M600327-Jlr200 |
0.501 |
|
| 2006 |
Jacobo SH, Chang CT, Lee GJ, Lawson JA, Powell WS, Pratico D, FitzGerald GA, Rokach J. Total synthesis of 8,12-iso-iPF3alpha-VI, an EPA-derived isoprostane: stereoselective introduction of the fifth asymmetric center. The Journal of Organic Chemistry. 71: 1370-9. PMID 16468784 DOI: 10.1021/Jo051916X |
0.609 |
|
| 2005 |
Powell WS, Rokach J. Biochemistry, biology and chemistry of the 5-lipoxygenase product 5-oxo-ETE. Progress in Lipid Research. 44: 154-83. PMID 15893379 DOI: 10.1016/J.Plipres.2005.04.002 |
0.454 |
|
| 2005 |
Kim S, Bellone S, Maxey KM, Powell WS, Lee GJ, Rokach J. Synthesis of 15R-PGD2: a potential DP2 receptor agonist. Bioorganic & Medicinal Chemistry Letters. 15: 1873-6. PMID 15780624 DOI: 10.1016/J.Bmcl.2005.02.011 |
0.503 |
|
| 2005 |
Kim S, Powell WS, Lawson JA, Jacobo SH, Pratico D, FitzGerald GA, Maxey K, Rokach J. iPF2alpha-III-17,18,19,20-d4: total synthesis and metabolism. Bioorganic & Medicinal Chemistry Letters. 15: 1613-7. PMID 15745808 DOI: 10.1016/J.Bmcl.2005.01.062 |
0.492 |
|
| 2005 |
Almishri W, Cossette C, Rokach J, Martin JG, Hamid Q, Powell WS. Effects of prostaglandin D2, 15-deoxy-Delta12,14-prostaglandin J2, and selective DP1 and DP2 receptor agonists on pulmonary infiltration of eosinophils in Brown Norway rats. The Journal of Pharmacology and Experimental Therapeutics. 313: 64-9. PMID 15590767 DOI: 10.1124/Jpet.104.079079 |
0.387 |
|
| 2005 |
Monneret G, Boumiza R, Gravel S, Cossette C, Bienvenu J, Rokach J, Powell WS. Effects of prostaglandin D(2) and 5-lipoxygenase products on the expression of CD203c and CD11b by basophils. The Journal of Pharmacology and Experimental Therapeutics. 312: 627-34. PMID 15388786 DOI: 10.1124/Jpet.104.074823 |
0.384 |
|
| 2005 |
Chang CT, Jacobo SH, Powell WS, Lawson JA, FitzGerald GA, Pratico D, Rokach J. A new synthetic approach for 4(S)-hydroxycyclopent-2-enone: A precursor to prostanoid synthesis Tetrahedron Letters. 46: 6325-6328. DOI: 10.1016/J.Tetlet.2005.07.035 |
0.537 |
|
| 2005 |
Jacobo SH, Adiyaman M, Chang C, Kang N, Powell WS, Rokach J. An efficient preparation of stereospecific β-hydroxy nitriles Tetrahedron Letters. 46: 161-164. DOI: 10.1016/J.Tetlet.2004.10.174 |
0.64 |
|
| 2004 |
Erlemann KR, Rokach J, Powell WS. Oxidative stress stimulates the synthesis of the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid by inflammatory cells. The Journal of Biological Chemistry. 279: 40376-84. PMID 15234979 DOI: 10.1074/Jbc.M401294200 |
0.408 |
|
| 2004 |
Stamatiou PB, Chan CC, Monneret G, Ethier D, Rokach J, Powell WS. 5-oxo-6,8,11,14-eicosatetraenoic acid stimulates the release of the eosinophil survival factor granulocyte/macrophage colony-stimulating factor from monocytes. The Journal of Biological Chemistry. 279: 28159-64. PMID 15136573 DOI: 10.1074/Jbc.M401537200 |
0.341 |
|
| 2004 |
Mercier F, Morin C, Cloutier M, Proteau S, Rokach J, Powell WS, Rousseau E. 5-Oxo-ETE regulates tone of guinea pig airway smooth muscle via activation of Ca2+ pools and Rho-kinase pathway. American Journal of Physiology. Lung Cellular and Molecular Physiology. 287: L631-40. PMID 15090369 DOI: 10.1152/Ajplung.00005.2004 |
0.343 |
|
| 2004 |
Praticò D, Rokach J, Lawson J, FitzGerald GA. F2-isoprostanes as indices of lipid peroxidation in inflammatory diseases. Chemistry and Physics of Lipids. 128: 165-71. PMID 15037161 DOI: 10.1016/J.Chemphyslip.2003.09.012 |
0.324 |
|
| 2004 |
Rokach J, Kim S, Bellone S, Lawson JA, Praticò D, Powell WS, FitzGerald GA. Total synthesis of isoprostanes: discovery and quantitation in biological systems. Chemistry and Physics of Lipids. 128: 35-56. PMID 15037151 DOI: 10.1016/J.Chemphyslip.2003.09.011 |
0.509 |
|
| 2004 |
Kim S, Jacobo SM, Chang CT, Bellone S, Powell WS, Rokach J. Silyl group deprotection by Pd/C/H2. A facile and selective method Tetrahedron Letters. 45: 1973-1976. DOI: 10.1016/J.Tetlet.2003.12.145 |
0.742 |
|
| 2003 |
Muro S, Hamid Q, Olivenstein R, Taha R, Rokach J, Powell WS. 5-oxo-6,8,11,14-eicosatetraenoic acid induces the infiltration of granulocytes into human skin. The Journal of Allergy and Clinical Immunology. 112: 768-74. PMID 14564360 DOI: 10.1016/S0091-6749(03)01888-8 |
0.389 |
|
| 2003 |
Monneret G, Cossette C, Gravel S, Rokach J, Powell WS. 15R-methyl-prostaglandin D2 is a potent and selective CRTH2/DP2 receptor agonist in human eosinophils. The Journal of Pharmacology and Experimental Therapeutics. 304: 349-55. PMID 12490611 DOI: 10.1124/Jpet.102.042937 |
0.36 |
|
| 2002 |
McNamara P, Lawson JA, Rokach J, FitzGerald GA. Isoprostane activation of the nuclear hormone receptor PPAR. Advances in Experimental Medicine and Biology. 507: 351-5. PMID 12664609 DOI: 10.1007/978-1-4615-0193-0_54 |
0.337 |
|
| 2002 |
Powell WS, Gravel S, Rokach J. Interactions between 5-oxo-ETE and chemokines in stimulating eosinophils. Advances in Experimental Medicine and Biology. 507: 237-42. PMID 12664591 DOI: 10.1007/978-1-4615-0193-0_36 |
0.39 |
|
| 2002 |
Monneret G, Li H, Vasilescu J, Rokach J, Powell WS. 15-Deoxy-delta 12,14-prostaglandins D2 and J2 are potent activators of human eosinophils. Journal of Immunology (Baltimore, Md. : 1950). 168: 3563-9. PMID 11907120 DOI: 10.4049/Jimmunol.168.7.3563 |
0.329 |
|
| 2002 |
Khanapure SP, Kim S, Penrose JF, Austen KF, Powell WS, Rokach J. An efficient approach to the synthesis of LTB4 and ω-substituted LTB4 metabolites Tetrahedron Letters. 43: 6063-6066. DOI: 10.1016/S0040-4039(02)01206-6 |
0.545 |
|
| 2002 |
Kim S, Lawson JA, Praticò D, FitzGerald GA, Rokach J. The first total synthesis of iPF4α-VI and its deuterated analog Tetrahedron Letters. 43: 2801-2805. DOI: 10.1016/S0040-4039(02)00398-2 |
0.535 |
|
| 2002 |
Girard Y, Atkinson JG, Belanger PC, Fuentes JJ, Rokach J, Rooney CS, Remy DC, Hunt CA. Synthesis, Chemistry And Photochemical Substitutions Of 6,11‐Dihydro‐5H‐Pyrrolo(2,1‐B)(3)Benzazepin‐11‐Ones Cheminform. 15. DOI: 10.1002/Chin.198406209 |
0.345 |
|
| 2001 |
Monneret G, Gravel S, Diamond M, Rokach J, Powell WS. Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor Blood. 98: 1942-1948. PMID 11535533 DOI: 10.1182/Blood.V98.6.1942 |
0.351 |
|
| 2001 |
Powell WS, Boismenu D, Khanapure SP, Rokach J. Quantitative analysis of 5-Oxo-6,8,11,14-eicosatetraenoic acid by electrospray mass spectrometry using a deuterium-labeled internal standard Analytical Biochemistry. 295: 262-266. PMID 11488631 DOI: 10.1006/Abio.2001.5206 |
0.37 |
|
| 2001 |
Praticò D, Lawson JA, Rokach J, FitzGerald GA. The isoprostanes in biology and medicine. Trends in Endocrinology and Metabolism: Tem. 12: 243-7. PMID 11445440 DOI: 10.1016/S1043-2760(01)00411-8 |
0.338 |
|
| 2001 |
Vezza R, Rokach J, FitzGerald GA. Prostaglandin F(2alpha) receptor-dependent regulation of prostaglandin transport. Molecular Pharmacology. 59: 1506-13. PMID 11353812 DOI: 10.1124/Mol.59.6.1506 |
0.303 |
|
| 2001 |
Powell WS, Ahmed S, Gravel S, Rokach J. Eotaxin and RANTES enhance 5-oxo-6,8,11,14-eicosatetraenoic acid-induced eosinophil chemotaxis Journal of Allergy and Clinical Immunology. 107: 272-278. PMID 11174193 DOI: 10.1067/Mai.2001.112847 |
0.371 |
|
| 2001 |
Kim S, Jung YJ, Lawson JA, FitzGerald GA, Rokach J. iPF2α-III metabolism. First total synthesis of 2,3-dinor iPF2α-III, a primary β-oxidation metabolite Tetrahedron Letters. 42: 8277-8280. DOI: 10.1016/S0040-4039(01)01794-4 |
0.544 |
|
| 2001 |
Kim S, Adiyaman Y, Saha G, Powell WS, Rokach J. A photoaffinity probe for 5-hydroxyeicosanoid dehydrogenase suitable for radioiodination Tetrahedron Letters. 42: 4445-4448. DOI: 10.1016/S0040-4039(01)00699-2 |
0.488 |
|
| 2000 |
Burke A, Lawson JA, Meagher EA, Rokach J, FitzGerald GA. Specific analysis in plasma and urine of 2,3-dinor-5, 6-dihydro-isoprostane F(2alpha)-III, a metabolite of isoprostane F(2alpha)-III and an oxidation product of gamma-linolenic acid. The Journal of Biological Chemistry. 275: 2499-504. PMID 10644705 DOI: 10.1074/Jbc.275.4.2499 |
0.321 |
|
| 2000 |
Saha G, Khanapure SP, Powell WS, Rokach J. The synthesis of a 5-HETE photoaffinity ligand Tetrahedron Letters. 41: 6313-6317. DOI: 10.1016/S0040-4039(00)01064-9 |
0.315 |
|
| 2000 |
Khanapure SP, Saha G, Powell WS, Rokach J. The design and synthesis of a 5-HETE affinity chromatography ligand for 5-hydroxyeicosanoid dehydrogenase Tetrahedron Letters. 41: 5807-5811. DOI: 10.1016/S0040-4039(00)00971-0 |
0.356 |
|
| 2000 |
Khanapure SP, Saha G, Sivendran S, Powell WS, Rokach J. Intramolecular sulfur-assisted NaBH4 reduction of esters synthesis of 5-oxo-ETE and 5-oxo-12-HETE Tetrahedron Letters. 41: 5653-5657. DOI: 10.1016/S0040-4039(00)00943-6 |
0.724 |
|
| 1999 |
Spokas EG, Rokach J, Wong PY. Leukotrienes, lipoxins, and hydroxyeicosatetraenoic acids Methods in Molecular Biology (Clifton, N.J.). 120: 213-247. PMID 10343320 DOI: 10.1385/1-59259-263-5:213 |
0.338 |
|
| 1999 |
Powell WS, Gravel S, Khanapure SP, Rokach J. Biological inactivation of 5-oxo-6,8,11,14-eicosatetraenoic acid by human platelets Blood. 93: 1086-1096. PMID 9920859 DOI: 10.1182/Blood.V93.3.1086.403K09_1086_1096 |
0.361 |
|
| 1999 |
Saha G, Basu MK, Kim S, Jung Y, Adiyaman Y, Adiyaman M, Powell WS, FitzGerald GA, Rokach J. A convenient strategy for the synthesis of β,γ-unsaturated aldehydes and acids. A construction of skipped dienes Tetrahedron Letters. 40: 7179-7183. DOI: 10.1016/S0040-4039(99)01498-7 |
0.532 |
|
| 1999 |
Adiyaman M, Jung Y, Kim S, Saha G, Powell WS, FitzGerald GA, Rokach J. A new method for the preparation of olefins from vicinal diols Tetrahedron Letters. 40: 4019-4022. DOI: 10.1016/S0040-4039(99)00675-9 |
0.498 |
|
| 1998 |
Stamatiou P, Hamid Q, Taha R, Yu W, Issekutz TB, Rokach J, Khanapure SP, Powell WS. 5-oxo-ETE induces pulmonary eosinophilia in an integrin-dependent manner in Brown Norway rats. The Journal of Clinical Investigation. 102: 2165-72. PMID 9854052 DOI: 10.1172/Jci1995 |
0.334 |
|
| 1998 |
Lawson JA, Li H, Rokach J, Adiyaman M, Hwang SW, Khanapure SP, FitzGerald GA. Identification of two major F2 isoprostanes, 8,12-iso- and 5-epi-8, 12-iso-isoprostane F2alpha-VI, in human urine. The Journal of Biological Chemistry. 273: 29295-301. PMID 9792628 DOI: 10.1074/Jbc.273.45.29295 |
0.304 |
|
| 1998 |
Adiyaman M, Lawson JA, Khanapure SP, FitzGerald GA, Rokach J. Total synthesis of 17,17,18,18-d4-iPF2alpha-VI and quantification of iPF2alpha-VI in human urine by gas chromatography/mass spectrometry. Analytical Biochemistry. 262: 45-56. PMID 9735147 DOI: 10.1006/Abio.1998.2767 |
0.378 |
|
| 1998 |
Berhane K, Ray AA, Khanapure SP, Rokach J, Powell WS. Calcium/calmodulin-dependent conversion of 5-oxoeicosanoids to 6,7- dihydro metabolites by a cytosolic olefin reductase in human neutrophils Journal of Biological Chemistry. 273: 20951-20959. PMID 9694844 DOI: 10.1074/Jbc.273.33.20951 |
0.396 |
|
| 1998 |
Praticò D, Barry OP, Lawson JA, Adiyaman M, Hwang SW, Khanapure SP, Iuliano L, Rokach J, FitzGerald GA. IPF2alpha-I: an index of lipid peroxidation in humans. Proceedings of the National Academy of Sciences of the United States of America. 95: 3449-54. PMID 9520386 DOI: 10.1073/Pnas.95.7.3449 |
0.333 |
|
| 1998 |
Khanapure SP, Powell WS, Rokach J. The total synthesis of 5-oxo-12(s)-hydroxy-6(e),8(z),10(e),14(z)- eicosatetraenoic acid and its 8,9-trans-isomer and their identification in human platelets Journal of Organic Chemistry. 63: 8976-8982. DOI: 10.1021/Jo9813282 |
0.371 |
|
| 1998 |
Khanapure SP, Shi XX, Powell WS, Rokach J. The Total Synthesis of Tritiated and Deuterated 5-Oxo-ETE, a Novel Inflammatory Mediator Journal of Organic Chemistry. 63: 4098-4102. DOI: 10.1021/Jo980280P |
0.383 |
|
| 1998 |
Khanapure SP, Shi XX, Powell WS, Rokach J. Total Synthesis of a Potent Proinflammatory 5-Oxo-ETE and Its 6,7-Dihydro Biotransformation Product Journal of Organic Chemistry. 63: 337-342. DOI: 10.1021/Jo9716993 |
0.427 |
|
| 1998 |
Pudukulathan Z, Manna S, Hwang SW, Khanapure SP, Lawson JA, FitzGerald GA, Rokach J. Diels-Alder approach to isoprostanes. Total synthesis of iPF(2α)-V Journal of the American Chemical Society. 120: 11953-11961. DOI: 10.1021/Ja982596K |
0.352 |
|
| 1998 |
Adiyaman M, Lawson JA, FitzGerald GA, Rokach J. Syntheses and identification of the most abundant urinary type VI isoprostanes Tetrahedron Letters. 39: 7039-7042. DOI: 10.1016/S0040-4039(98)01524-X |
0.308 |
|
| 1997 |
Khanapure SP, Wang SS, Powell WS, Rokach J. Synthesis of 10,11-Dihydro-12-oxo-LTB(4), a Key Biochemical Intermediate. The Journal of Organic Chemistry. 62: 325-330. PMID 11671406 DOI: 10.1021/Jo9614957 |
0.408 |
|
| 1997 |
Rokach J, Khanapure SP, Hwang SW, Adiyaman M, Lawson JA, FitzGerald GA. Nomenclature of isoprostanes: a proposal. Prostaglandins. 54: 853-73. PMID 9533181 DOI: 10.1016/S0090-6980(97)00184-6 |
0.339 |
|
| 1997 |
Rokach J, Khanapure SP, Hwang SW, Adiyaman M, Lawson JA, FitzGerald GA. The isoprostanes: a perspective. Prostaglandins. 54: 823-51. PMID 9533180 DOI: 10.1016/S0090-6980(97)00183-4 |
0.385 |
|
| 1997 |
Kunapuli P, Lawson JA, Rokach J, FitzGerald GA. Functional characterization of the ocular prostaglandin f2alpha (PGF2alpha) receptor. Activation by the isoprostane, 12-iso-PGF2alpha. The Journal of Biological Chemistry. 272: 27147-54. PMID 9341156 DOI: 10.1074/Jbc.272.43.27147 |
0.349 |
|
| 1997 |
Powell WS, Wang L, Khanapure SP, Manna S, Rokach J. High-pressure liquid chromatography of oxo-eicosanoids derived from arachidonic acid Analytical Biochemistry. 247: 17-24. PMID 9126365 DOI: 10.1006/Abio.1997.2024 |
0.36 |
|
| 1997 |
Adiyaman M, Li H, Lawson JA, Hwang SW, Khanapure SP, FitzGerald GA, Rokach J. First total synthesis of isoprostane IPF(2α)-III Tetrahedron Letters. 38: 3339-3342. DOI: 10.1016/S0040-4039(97)00622-9 |
0.331 |
|
| 1996 |
Lam BK, Penrose JF, Rokach J, Xu K, Baldasaro MH, Austen KF. Molecular cloning, expression and characterization of mouse leukotriene C4 synthase European Journal of Biochemistry. 238: 606-612. PMID 8706658 DOI: 10.1111/J.1432-1033.1996.0606W.X |
0.306 |
|
| 1996 |
Adiyaman M, Lawson JA, Hwang SW, Khanapure SP, FitzGerald GA, Rokach J. Total synthesis of a novel isoprostane IPF(2α)-I and its identification in biological fluids Tetrahedron Letters. 37: 4849-4852. DOI: 10.1016/0040-4039(96)00973-2 |
0.3 |
|
| 1996 |
Shi XX, Khanapure SP, Rokach J. Deblocking of dithioacetals and oxathioacetals using periodic acid under mild nonaqueous conditions Tetrahedron Letters. 37: 4331-4334. DOI: 10.1016/0040-4039(96)00838-6 |
0.356 |
|
| 1996 |
Hwang SW, Adiyaman M, Khanapure SP, Rokach J. Total Synthesis of 12-epi-PGF2α Tetrahedron Letters. 37: 779-782. DOI: 10.1016/0040-4039(95)02390-9 |
0.305 |
|
| 1995 |
Khanapure SP, Najafi N, Manna S, Yang JJ, Rokach J. An efficient synthesis of 4(S)-hydroxycyclopent-2-enone The Journal of Organic Chemistry. 60: 7548-7551. DOI: 10.1021/Jo00128A029 |
0.314 |
|
| 1995 |
Adiyaman M, Khanapure SP, Hwang SW, Rokach J. Regioncontrolled formation of iodohy dnns and expoxides from Vic-diols Tetrahedron Letters. 36: 7367-7370. DOI: 10.1016/0040-4039(95)01658-9 |
0.316 |
|
| 1995 |
Wang SS, Shi XX, Powell WS, Tieman T, Feinmark SJ, Rokach J. Total synthesis of proinflammatory dihydro-12-KETE metabolites Tetrahedron Letters. 36: 513-516. DOI: 10.1016/0040-4039(94)02298-P |
0.411 |
|
| 1994 |
Hwang SW, Adiyaman M, Khanapure S, Schio L, Rokach J. Total Synthesis of 8-epi-PGF2.alpha.. A Novel Strategy for the Synthesis of Isoprostanes Journal of the American Chemical Society. 116: 10829-10830. DOI: 10.1021/Ja00102A076 |
0.303 |
|
| 1994 |
Wang SS, Rokach J. Total synthesis of 11-R,12-R-dihydroxyeicosatrienoic acid, a metabolite of the cytochrome P-450 epoxygenase pathway Tetrahedron Letters. 35: 6239-6242. DOI: 10.1016/S0040-4039(00)73401-0 |
0.315 |
|
| 1994 |
Wang SS, Rokach J, Powell WS, Dekle C, Feinmark SJ. Synthesis of 12-KETE and its 8,9-trans-isomer Tetrahedron Letters. 35: 4051-4054. DOI: 10.1016/S0040-4039(00)73109-1 |
0.387 |
|
| 1993 |
Rondot B, Durand T, Girard JP, Rossi JC, Schio L, Khanapure SP, Rokach J. A free radical route to syn lactones and other prostanoid intermediates in isoprostaglandin synthesis Tetrahedron Letters. 34: 8245-8248. DOI: 10.1016/S0040-4039(00)61401-6 |
0.368 |
|
| 1991 |
Naccache PH, Leblanc Y, Rokach J, Patrignani P, Laclos BFd, Borgeat P. Calcium mobilization and right-angle light scatter responses to 12-oxo-derivatives of arachidonic acid in neutrophils: evidence for the involvement of the leukotriene B4 receptor Bba - Molecular Cell Research. 1133: 102-106. PMID 1661162 DOI: 10.1016/0167-4889(91)90247-U |
0.333 |
|
| 1990 |
Labelle M, Falgueyret JP, Riendeau D, Rokach J. Synthesis of two analogues of arachidonic acid and their reactions with 12-Lipoxygenase Tetrahedron. 46: 6301-6310. DOI: 10.1016/S0040-4020(01)96002-8 |
0.397 |
|
| 1990 |
Prasit P, Robertson G, Rokach J. Inversion of configurations of contiguous carbinol centres: application to the synthesis of both enantiomers of natural products from the same enantiomerically pure starting material Carbohydrate Research. 202: 93-104. DOI: 10.1016/0008-6215(90)84073-4 |
0.33 |
|
| 1989 |
Patrignani P, Morton H, Cirino M, Lord A, Charette L, Gillard J, Rokach J, Patrono C. Fractional conversion of thromboxane A2 and B2 to urinary 2,3-dinor-thromboxane B2 and 11-dehydrothromboxane B2 in the cynomolgus monkey Bba - General Subjects. 992: 71-77. PMID 2752041 DOI: 10.1016/0304-4165(89)90052-4 |
0.319 |
|
| 1989 |
Rokach J, Young RN. The development of new antileukotriene drugs: Specific leukotriene D4 antagonists and 5-lipoxygenase inhibitors Advances in Experimental Medicine and Biology. 259: 75-108. PMID 2560345 DOI: 10.1007/978-1-4684-5700-1_4 |
0.407 |
|
| 1989 |
Tagari P, Foster A, Delorme D, Girard Y, Rokach J. Metabolism and excretion of exogenous [3H]-LTC4 in primates. Prostaglandins. 37: 629-40. PMID 2549573 DOI: 10.1016/0090-6980(89)90101-9 |
0.331 |
|
| 1989 |
Mais DE, Yoakim C, Guindon Y, Gillard JW, Rokach J, Halushka PV. Photoaffinity labelling of the human platelet thromboxane A2/prostaglandin H2 receptor. Biochimica Et Biophysica Acta. 1012: 184-90. PMID 2525928 DOI: 10.1016/0167-4889(89)90094-3 |
0.304 |
|
| 1989 |
Riendeau D, Falgueyret JP, Nathaniel DJ, Rokach J. Sensitivity of immunoaffinity-purified porcine 5-lipoxygenase to inhibitors and activating lipid hydroperoxides Biochemical Pharmacology. 38: 2313-2321. PMID 2502118 DOI: 10.1016/0006-2952(89)90471-1 |
0.329 |
|
| 1989 |
Delorme D, Girard Y, Rokach J. Total synthesis of leukotriene E4 metabolites and precursors to radiolabeled forms of those metabolites Journal of Organic Chemistry. 54: 3635-3640. DOI: 10.1021/Jo00276A025 |
0.397 |
|
| 1988 |
Delorme D, Foster A, Girard Y, Rokach J. Synthesis of beta-oxidation products as potential leukotriene metabolites and their detection in bile of anesthetized rat. Prostaglandins. 36: 291-302. PMID 3237994 DOI: 10.1016/0090-6980(88)90071-8 |
0.325 |
|
| 1988 |
Falgueyret JP, Leblanc Y, Rokach J, Riendeau D. NAD(P)H-dependent reduction of 12-ketoeicosatetraenoic acid to 12(R)-and 12(S)-hydroxyeicosatetraenoic acid by rat liver microsomes Biochemical and Biophysical Research Communications. 156: 1083-1089. PMID 3190686 DOI: 10.1016/S0006-291X(88)80743-5 |
0.345 |
|
| 1988 |
Prasit P, Rokach J. Inversion of configurations of contiguous carbinol centers Journal of Organic Chemistry. 53: 4421-4422. DOI: 10.1021/Jo00253A050 |
0.301 |
|
| 1987 |
Ueda N, Yokoyama C, Yamamoto S, Fitzsimmons BJ, Rokach J, Oates JA, Brash AR. Lipoxin synthesis by arachidonate 12-lipoxygenase purified from porcine leukocytes Biochemical and Biophysical Research Communications. 149: 1063-1069. PMID 3122743 DOI: 10.1016/0006-291X(87)90516-X |
0.352 |
|
| 1987 |
Kühn H, Wiesner R, Alder L, Fitzsimmons BJ, Rokach J, Brash AR. Formation of lipoxin B by the pure reticulocyte lipoxygenase via sequential oxygenation of the substrate European Journal of Biochemistry. 169: 593-601. PMID 3121318 DOI: 10.1111/J.1432-1033.1987.Tb13650.X |
0.361 |
|
| 1987 |
Leblanc Y, Fitzsimmons BJ, Charleson S, Alexander P, Evans JF, Rokach J. Analogs of leukotriene B4: Effects of modification of the hydroxyl groups on leukocyte aggregation and binding to leukocyte leukotriene B4 receptors Prostaglandins. 33: 617-625. PMID 3035618 DOI: 10.1016/0090-6980(87)90029-3 |
0.349 |
|
| 1987 |
Foster A, Fitzsimmons B, Rokach J, Letts G. Evidence of in-vivo W-oxidation of peptide leukotrienes in the rat: Biliary excretion of 20-CO2H N-acetyl LTE4 Biochemical and Biophysical Research Communications. 148: 1237-1245. PMID 2825679 DOI: 10.1016/S0006-291X(87)80265-6 |
0.311 |
|
| 1987 |
Fitzsimmons BJ, Leblanc Y, Rokach J. [4 + 2] Cycloaddition of azodicarboxylate and glycals: A novel and simple method for the preparation of 2-amino-2-deoxy carbohydrates Journal of the American Chemical Society. 109: 285-286. DOI: 10.1021/Ja00235A050 |
0.312 |
|
| 1987 |
Leblanc Y, Fitzsimmons BJ, Rokach J, Ueda N, Yamamoto S. Synthesis of 5S-hydroxy-14, 15 LTA4 a biogenic precursor to the lipoxins Tetrahedron Letters. 28: 3449-3452. DOI: 10.1016/S0040-4039(00)96323-8 |
0.34 |
|
| 1986 |
Rokach J, Fitzsimmons BJ, Adams J, Evans JF, Leblanc Y. The lipoxins: Determination of their biosynthesis Pharmacological Research Communications. 18: 11-23. PMID 3095848 DOI: 10.1016/0031-6989(86)90034-2 |
0.363 |
|
| 1986 |
Leblanc Y, Fitzsimmons BJ, Adams J, Perez F, Rokach J. The total synthesis of 12-HETE (12-hydroxyeicosatetraenoic acid) and 12,20-diHETE Journal of Organic Chemistry. 51: 789-793. DOI: 10.1021/Jo00356A004 |
0.385 |
|
| 1985 |
Adams J, Fitzsimmons BJ, Girard Y, Leblanc Y, Evans JF, Rokach J. Enantiospecific and stereospecific synthesis of lipoxin A. Stereochemical assignment of the natural lipoxin A and its possible biosynthesis Journal of the American Chemical Society. 107: 464-469. DOI: 10.1021/Ja00288A032 |
0.346 |
|
| 1985 |
Rokach J, Adams J. Synthesis of leukotrienes and lipoxygenase products Accounts of Chemical Research. 18: 87-93. DOI: 10.1021/Ar00111A004 |
0.303 |
|
| 1984 |
Rokach J, Hayes EC, Girard Y, Lombardo DL, Maycock AL, Rosenthal AS, Young RN, Zamboni R, Zweerink HJ. The development of sensitive and specific radioimmunoassays for leukotrienes. Prostaglandins, Leukotrienes, and Medicine. 13: 21-5. PMID 6324239 DOI: 10.1016/0262-1746(84)90098-2 |
0.338 |
|
| 1984 |
Evans J, Ford-Hutchinson AW, Fitzsimmons B, Rokach J. Biological activities of isomers of 8, 15-dihydroxyeicosatetraenoic acid Prostaglandins. 28: 435-438. PMID 6096926 DOI: 10.1016/0090-6980(84)90027-3 |
0.359 |
|
| 1984 |
Zamboni R, Milette S, Rokach J. Stereospecific synthesis of 11S, 12S-oxido 5Z, 7E, 9E, 14Z-eicosatetraenoic acid Tetrahedron Letters. 25: 5835-5838. DOI: 10.1016/S0040-4039(01)81698-1 |
0.331 |
|
| 1984 |
Adams J, Fitzsimmons BJ, Rokach J. Synthesis of lipoxins: Total synthesis of conjugated trihydroxy eicosatetraenoic acids Tetrahedron Letters. 25: 4713-4716. DOI: 10.1016/S0040-4039(01)81500-8 |
0.386 |
|
| 1984 |
Adams J, Milette S, Rokach J, Zamboni R. Oxidized leukotrienes: Synthesis of 20-OH and 20-COOH LTD4. Possible metabolites in the lipoxygenase pathway Tetrahedron Letters. 25: 2179-2182. DOI: 10.1016/S0040-4039(01)80204-5 |
0.357 |
|
| 1984 |
Adams J, Leblanc Y, Rokach J. Synthesis of 5S,12S - diHETE (LTBx) Tetrahedron Letters. 25: 1227-1230. DOI: 10.1016/S0040-4039(01)80119-2 |
0.331 |
|
| 1984 |
Fitzsimmons BJ, Rokach J. The total syntheses of several 8, 15 dihydroxy arachidonic acid derivatives (8,15, LTB's) Tetrahedron Letters. 25: 3043-3046. DOI: 10.1016/0040-4039(84)80003-9 |
0.351 |
|
| 1983 |
Ford-Hutchinson AW, Rackham A, Zamboni R, Rokach J, Roy S. Comparative biological activities of synthetic leukotriene B4 and its omega-oxidation products. Prostaglandins. 25: 29-37. PMID 6302739 DOI: 10.1016/0090-6980(83)90132-6 |
0.318 |
|
| 1983 |
Girard Y, Atkinson JG, Belanger PC, Fuentes JJ, Rokach J, Rooney CS, Remy DC, Hunt CA. Synthesis, chemistry, and photochemical substitutions of 6,11-dihydro-5H-pyrrolo[2,1-b][3]benzazepin-11-ones Journal of Organic Chemistry. 48: 3220-3234. DOI: 10.1021/Jo00167A015 |
0.301 |
|
| 1983 |
Zamboni R, Milette S, Rokach J. The stereospecific synthesis of 14S,15S-oxido 5Z,8Z,10E,12E-eicosatetraenoic acid Tetrahedron Letters. 24: 4899-4902. DOI: 10.1016/S0040-4039(01)99805-3 |
0.339 |
|
| 1983 |
Zamboni R, Rokach J. Synthesis of the aza analog of LTA4 Tetrahedron Letters. 24: 331-334. DOI: 10.1016/S0040-4039(00)81399-4 |
0.361 |
|
| 1983 |
Kakushima M, Hamel P, Frenette R, Rokach J. Regioselective synthesis of acylpyrroles Journal of Organic Chemistry. 48: 3214-3219. DOI: 10.1002/Chin.198406169 |
0.374 |
|
| 1982 |
Young RN, Kakushima M, Rokach J. Studies on the preparation of conjugates of leukotriene C4 with proteins for development of an immunoassay for SRS-A (1) Prostaglandins. 23: 603-613. PMID 7111766 DOI: 10.1016/0090-6980(82)90120-4 |
0.318 |
|
| 1982 |
Jones T, Masson P, Hamel R, Brunet G, Holme G, Girard Y, Larue M, Rokach J. Biological activity of leukotriene sulfones on respiratory tissues. Prostaglandins. 24: 279-91. PMID 6897297 DOI: 10.1016/0090-6980(82)90154-X |
0.314 |
|
| 1982 |
Zamboni R, Rokach J. Simple efficient synthesis of LTB4 and 12-epi-LTB4 Tetrahedron Letters. 23: 2631-2634. DOI: 10.1016/S0040-4039(00)87415-8 |
0.304 |
|
| 1982 |
Girard Y, Larue M, Jones TR, Rokach J. Synthesis of the sulfones of leukotriene C4, D4, and E4 Tetrahedron Letters. 23: 1023-1026. DOI: 10.1016/S0040-4039(00)87012-4 |
0.337 |
|
| 1982 |
Guindon Y, Zamboni R, Lau CK, Rokach J. Stereospecific synthesis of leukotriene B4 (LTB4) Tetrahedron Letters. 23: 739-742. DOI: 10.1016/S0040-4039(00)86935-X |
0.309 |
|
| 1982 |
Zamboni R, Rokach J. Stereospecific synthesis of two metabolites of LTB4 Tetrahedron Letters. 23: 4751-4754. DOI: 10.1016/S0040-4039(00)85704-4 |
0.328 |
|
| 1981 |
Rokach J, Girard Y, Guidon Y, Atkinson JG, Larue M, Young RN, Masson P, Holme G. The synthesis of leukotrienes. Progress in Lipid Research. 20: 905-7. PMID 7342143 DOI: 10.1016/0163-7827(81)90169-7 |
0.331 |
|
| 1981 |
Young RN, Coombs W, Guindon Y, Rokach J, Ethier D, Hall R. The preparation of octahydro leukotrienes C, D, and E via a stereoselective sulfenyllactonization reaction Tetrahedron Letters. 22: 4933-4936. DOI: 10.1016/S0040-4039(01)92385-8 |
0.38 |
|
| 1981 |
Rokach J, Lau CK, Zamboni R, Guindon Y. A C-glycoside route to leukotrienes Tetrahedron Letters. 22: 2763-2766. DOI: 10.1016/S0040-4039(01)90546-5 |
0.349 |
|
| 1981 |
Rokach J, Zamboni R, Lau CK, Guindon Y. The stereospecific synthesis of leukotriene A4 (LTA4), 5-epi-LTA4, 6-epi-LTA4 and 5-epi,6-epi-LTA4 Tetrahedron Letters. 22: 2759-2762. DOI: 10.1016/S0040-4039(01)90545-3 |
0.359 |
|
| 1981 |
Rokach J, Young RN, Kakushima M. Synthesis of leukotrienes - new synthesis of natural leukotriene A4 Tetrahedron Letters. 22: 979-982. DOI: 10.1016/S0040-4039(01)82844-6 |
0.317 |
|
| 1980 |
Morris HR, Taylor GW, Rokach J, Girard Y, Piper PJ, Tippins JR, Samhoun MN. Slow reacting substance of anaphylaxis, SRS-A; assignment of the stereochemistry. Prostaglandins. 20: 601-7. PMID 7422903 DOI: 10.1016/0090-6980(80)90047-7 |
0.373 |
|
| 1980 |
Rokach J, Girard Y, Guindon Y, Atkinson JG, Larue M, Young RN, Masson P, Holme G. The synthesis of a leukotriene with SRS-like activity Tetrahedron Letters. 21: 1485-1488. DOI: 10.1016/S0040-4039(00)92753-9 |
0.329 |
|
| 1979 |
Atkinson JG, Girard Y, Rokach J, Rooney CS, McFarlane CS, Rackham A, Share NN. Kojic amine--a novel gamma-aminobutyric acid analogue. Journal of Medicinal Chemistry. 22: 99-106. PMID 423190 DOI: 10.1021/Jm00187A022 |
0.355 |
|
| 1979 |
Girard Y, Atkinson JG, Rokach J. A new synthesis of 1,2,4-benzothiadiazines and a selective preparation of o-aminobenzenesulphonamides Journal of the Chemical Society, Perkin Transactions 1. 1043-1047. DOI: 10.1039/P19790001043 |
0.342 |
|
| 1979 |
Rokach J, Hamel P, Girard Y, Reader G. General method for the preparation of N-monosubstituted 3-isothiazole and 3-(1,2,5-thiadiazol)amines. Preparation of a new class of 2-substituted 1,2,5-thiadiazol-3(2H)-ones Journal of Organic Chemistry. 44: 1118-1124. DOI: 10.1021/Jo01321A019 |
0.318 |
|
| 1979 |
Rokach J, Girard Y, Atkinson JG, Rooney CS. Tricyclic chemistry. Synthesis and chemistry of a novel polyheterocycle Journal of Heterocyclic Chemistry. 16: 205-207. DOI: 10.1002/Jhet.5570160143 |
0.301 |
|
| 1979 |
Atkinson JG, Girard Y, Rokach J, Rooney CS, Mcfarlane CS, Rackham A, Share NN. Kojic Amine - A Novel Γ-Aminobutyric Acid Analog Cheminform. 10. DOI: 10.1002/Chin.197921247 |
0.356 |
|
| 1978 |
Rokach J, Hamel P. A general method for the preparation of N-monosubstituted-3-isothiazolamines Journal of Heterocyclic Chemistry. 15: 695-696. DOI: 10.1002/Jhet.5570150439 |
0.319 |
|
| 1978 |
Rokach J, Girard Y. An unexpected and efficient synthesis of 3-chloro-4-cyanopyridine Journal of Heterocyclic Chemistry. 15: 683-684. DOI: 10.1002/Jhet.5570150433 |
0.305 |
|
| 1974 |
Mandel LR, Rosegay A, Walker RW, VandenHeuvel WJ, Rokach J. 5-Methyltetrahydrofolic acid as a mediator in the formation of pyridoindoles Science. 186: 471-473. PMID 4424614 DOI: 10.1126/Science.186.4165.741 |
0.315 |
|
| 1973 |
Rokach J, Girard Y, Atkinson JG. A Novel Synthesis of N-Styryl Heterocycles Canadian Journal of Chemistry. 51: 3765-3770. DOI: 10.1002/Chin.197413281 |
0.364 |
|
| 1966 |
Rokach J, Elad D. Photoamidation. IV. The light-induced amidation of α,β-unsaturated esters Journal of Organic Chemistry. 31: 4210-4215. DOI: 10.1021/Jo01350A078 |
0.317 |
|
| 1965 |
Elad D, Rokach J. Photoamidation. III. The light-induced amidation of nonterminal olefins Journal of Organic Chemistry. 30: 3361-3364. DOI: 10.1021/Jo01021A023 |
0.335 |
|
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