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Changcheng Zhou, Ph.D. - Publications

Affiliations: 
2004 University of California, Irvine, Irvine, CA 
Area:
Cell Biology
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Liu J, Hernandez R, Li X, Meng Z, Chen H, Zhou C. Pregnane X Receptor Mediates Atherosclerosis Induced by Dicyclohexyl Phthalate in LDL Receptor-Deficient Mice. Cells. 11. PMID 35406689 DOI: 10.3390/cells11071125  0.339
2020 Sui Y, Meng Z, Park SH, Lu W, Livelo C, Chen Q, Zhou T, Zhou C. Myeloid-specific deficiency of pregnane X receptor decreases atherosclerosis in LDL receptor-deficient mice. Journal of Lipid Research. PMID 32170024 DOI: 10.1194/Jlr.Ra119000122  0.454
2020 Hoffman JB, Petriello MC, Morris AJ, Mottaleb MA, Sui Y, Zhou C, Deng P, Wang C, Hennig B. Prebiotic inulin consumption reduces dioxin-like PCB 126-mediated hepatotoxicity and gut dysbiosis in hyperlipidemic Ldlr deficient mice. Environmental Pollution (Barking, Essex : 1987). 261: 114183. PMID 32105967 DOI: 10.1016/J.Envpol.2020.114183  0.373
2019 Lu W, Park SH, Meng Z, Wang F, Zhou C. Deficiency of Adipocyte IKKβ Affects Atherosclerotic Plaque Vulnerability in Obese LDLR Deficient Mice. Journal of the American Heart Association. 8: e012009. PMID 31203708 DOI: 10.1161/Jaha.119.012009  0.349
2019 Meng Z, Gwag T, Sui Y, Park SH, Zhou X, Zhou C. The atypical antipsychotic quetiapine induces hyperlipidemia by activating intestinal PXR signaling. Jci Insight. 4. PMID 30728326 DOI: 10.1172/Jci.Insight.125657  0.446
2019 Gwag T, Meng Z, Sui Y, Helsley RN, Park SH, Wang S, Greenberg RN, Zhou C. Non-nucleoside reverse transcriptase inhibitor efavirenz activates PXR to induce hypercholesterolemia and hepatic steatosis. Journal of Hepatology. PMID 30677459 DOI: 10.1016/J.Jhep.2018.12.038  0.329
2018 Memetimin H, Li D, Tan K, Zhou C, Liang Y, Wu Y, Wang S. Myeloid Specific Deletion of Thrombospondin 1 Protects Against Inflammation and Insulin Resistance in Long-term Diet-induced Obese Male Mice. American Journal of Physiology. Endocrinology and Metabolism. PMID 30351986 DOI: 10.1152/Ajpendo.00273.2018  0.34
2018 Wang F, Liu Z, Park SH, Gwag T, Lu W, Ma M, Sui Y, Zhou C. Myeloid β-Catenin Deficiency Exacerbates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29724817 DOI: 10.1161/Atvbaha.118.311059  0.313
2018 Sui Y, Park SH, Wang F, Zhou C. Perinatal bisphenol A exposure increases atherosclerosis in adult male PXR-humanized mice. Endocrinology. PMID 29425287 DOI: 10.1210/En.2017-03250  0.353
2018 Sui Y, Liu Z, Park SH, Thatcher SE, Zhu B, Fernandez JP, Molina H, Kern PA, Zhou C. IKKβ is a β-catenin kinase that regulates mesenchymal stem cell differentiation. Jci Insight. 3. PMID 29367460 DOI: 10.1172/Jci.Insight.96660  0.328
2018 Sui Y, Park S, Kern PA, Temel R, Zhou C. IKKß and Wnt/ß-Catenin Signaling Interaction Regulates Adipogenesis and Osteogenesis in Mesenchymal Stem Cells of Nonhuman Primates and Humans Diabetes. 67. DOI: 10.2337/Db18-288-Lb  0.35
2018 Wang F, Liu Z, Park S, Gwag T, Lu W, Ma M, Sui Y, Zhou C. Abstract 632: Myeloid beta catenin Deficiency Exacerbates Atherosclerosis in Low-density Lipoprotein-receptor Deficient Mice Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.632  0.323
2017 Helsley RN, Zhou C. Epigenetic impact of endocrine disrupting chemicals on lipid homeostasis and atherosclerosis: a pregnane X receptor-centric view. Environmental Epigenetics. 3. PMID 29119010 DOI: 10.1093/Eep/Dvx017  0.391
2016 Park SH, Liu Z, Sui Y, Helsley RN, Zhu B, Powell DK, Kern PA, Zhou C. IKKβ is essential for adipocyte survival and adaptive adipose remodeling in obesity. Diabetes. PMID 26993069 DOI: 10.2337/Db15-1156  0.358
2016 Helsley RN, Sui Y, Park SH, Liu Z, Lee RG, Zhu B, Kern PA, Zhou C. Targeting IKKβ in adipocyte lineage cells for treatment of obesity and metabolic dysfunctions. Stem Cells (Dayton, Ohio). PMID 26991836 DOI: 10.1002/Stem.2358  0.379
2016 Zhou C. Novel functions of PXR in cardiometabolic disease. Biochimica Et Biophysica Acta. PMID 26924429 DOI: 10.1016/J.Bbagrm.2016.02.015  0.38
2015 Cui W, Maimaitiyiming H, Zhou Q, Norman H, Zhou C, Wang S. Interaction of thrombospondin1 and CD36 contributes to obesity-associated podocytopathy. Biochimica Et Biophysica Acta. 1852: 1323-33. PMID 25835637 DOI: 10.1016/J.Bbadis.2015.03.010  0.34
2015 Sui Y, Helsley RN, Park SH, Song X, Liu Z, Zhou C. Intestinal pregnane X receptor links xenobiotic exposure and hypercholesterolemia. Molecular Endocrinology (Baltimore, Md.). 29: 765-76. PMID 25811240 DOI: 10.1210/Me.2014-1355  0.452
2014 Sui Y, Park SH, Xu J, Monette S, Helsley RN, Han SS, Zhou C. IKKβ links vascular inflammation to obesity and atherosclerosis. The Journal of Experimental Medicine. 211: 869-86. PMID 24799533 DOI: 10.1084/Jem.20131281  0.385
2014 Sui Y, Park SH, Helsley RN, Sunkara M, Gonzalez FJ, Morris AJ, Zhou C. Bisphenol A increases atherosclerosis in pregnane X receptor-humanized ApoE deficient mice. Journal of the American Heart Association. 3: e000492. PMID 24755147 DOI: 10.1161/Jaha.113.000492  0.4
2013 Helsley RN, Sui Y, Ai N, Park SH, Welsh WJ, Zhou C. Pregnane X receptor mediates dyslipidemia induced by the HIV protease inhibitor amprenavir in mice. Molecular Pharmacology. 83: 1190-9. PMID 23519392 DOI: 10.1124/Mol.113.085753  0.417
2012 Park SH, Sui Y, Gizard F, Xu J, Rios-Pilier J, Helsley RN, Han SS, Zhou C. Myeloid-specific IκB kinase β deficiency decreases atherosclerosis in low-density lipoprotein receptor-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2869-76. PMID 23023371 DOI: 10.1161/Atvbaha.112.254573  0.394
2012 Sui Y, Ai N, Park SH, Rios-Pilier J, Perkins JT, Welsh WJ, Zhou C. Bisphenol A and its analogues activate human pregnane X receptor. Environmental Health Perspectives. 120: 399-405. PMID 22214767 DOI: 10.1289/Ehp.1104426  0.37
2011 Sui Y, Xu J, Rios-Pilier J, Zhou C. Deficiency of PXR decreases atherosclerosis in apoE-deficient mice. Journal of Lipid Research. 52: 1652-9. PMID 21685500 DOI: 10.1194/Jlr.M017376  0.375
2011 Zhou C, Pridgen B, King N, Xu J, Breslow JL. Hyperglycemic Ins2AkitaLdlr⁻/⁻ mice show severely elevated lipid levels and increased atherosclerosis: a model of type 1 diabetic macrovascular disease. Journal of Lipid Research. 52: 1483-93. PMID 21606463 DOI: 10.1194/Jlr.M014092  0.339
2009 Zhou C, King N, Chen KY, Breslow JL. Activation of PXR induces hypercholesterolemia in wild-type and accelerates atherosclerosis in apoE deficient mice. Journal of Lipid Research. 50: 2004-13. PMID 19436068 DOI: 10.1194/Jlr.M800608-Jlr200  0.396
2009 Zhou C, Verma S, Blumberg B. The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism. Nuclear Receptor Signaling. 7: e001. PMID 19240808 DOI: 10.1621/Nrs.07001  0.569
2007 Zhou C, Poulton EJ, Grün F, Bammler TK, Blumberg B, Thummel KE, Eaton DL. The dietary isothiocyanate sulforaphane is an antagonist of the human steroid and xenobiotic nuclear receptor. Molecular Pharmacology. 71: 220-9. PMID 17028159 DOI: 10.1124/Mol.106.029264  0.417
2006 Zhou C, Tabb MM, Nelson EL, Grün F, Verma S, Sadatrafiei A, Lin M, Mallick S, Forman BM, Thummel KE, Blumberg B. Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation. The Journal of Clinical Investigation. 116: 2280-2289. PMID 16841097 DOI: 10.1172/Jci26283  0.56
2006 Zhou C, Assem M, Tay JC, Watkins PB, Blumberg B, Schuetz EG, Thummel KE. Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. The Journal of Clinical Investigation. 116: 1703-12. PMID 16691293 DOI: 10.1172/Jci27793  0.36
2004 Zhou C, Tabb MM, Sadatrafiei A, Grün F, Sun A, Blumberg B. Hyperforin, the active component of St. John's wort, induces IL-8 expression in human intestinal epithelial cells via a MAPK-dependent, NF-kappaB-independent pathway. Journal of Clinical Immunology. 24: 623-36. PMID 15622447 DOI: 10.1007/S10875-004-6248-Z  0.309
2004 Zhou C, Tabb MM, Sadatrafiei A, Grün F, Blumberg B. Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 1075-82. PMID 15269186 DOI: 10.1124/Dmd.104.000299  0.381
2004 Tabb MM, Kholodovych V, Grün F, Zhou C, Welsh WJ, Blumberg B. Highly chlorinated PCBs inhibit the human xenobiotic response mediated by the steroid and xenobiotic receptor (SXR). Environmental Health Perspectives. 112: 163-9. PMID 14754570 DOI: 10.1289/Ehp.6560  0.369
2002 Grün F, Venkatesan RN, Tabb MM, Zhou C, Cao J, Hemmati D, Blumberg B. Benzoate X receptors alpha and beta are pharmacologically distinct and do not function as xenobiotic receptors. The Journal of Biological Chemistry. 277: 43691-7. PMID 12198127 DOI: 10.1074/Jbc.M206553200  0.368
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