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Jasvinder K. Atwal, Ph.D. - Publications

Affiliations: 
2002 McGill University, Montreal, QC, Canada 
Area:
Neuroscience Biology
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ferl GZ, Fuji RN, Atwal JK, Sun T, Ramanujan S, Quartino AL. Mechanistic Modeling of Soluble Aβ Dynamics and Target Engagement in the Brain by Anti-Aβ mAbs in Alzheimer's Disease. Current Alzheimer Research. PMID 32116192 DOI: 10.2174/1567205017666200302122307  0.319
2019 Meilandt WJ, Maloney JA, Imperio J, Lalehzadeh G, Earr T, Crowell S, Bainbridge TW, Lu Y, Ernst JA, Fuji RN, Atwal JK. Characterization of the selective in vitro and in vivo binding properties of crenezumab to oligomeric Aβ. Alzheimer's Research & Therapy. 11: 97. PMID 31787113 DOI: 10.1186/S13195-019-0553-5  0.323
2017 Ferl GZ, Fuji RN, Atwal J, Ramanujan S, Quartino A. [P1-109]: MATHEMATICAL MODEL OF AMYLOID BETA (Aβ) DYNAMICS TO ASSESS TARGET ENGAGEMENT OF SOLUBLE Aβ OLIGOMERS BY CRENEZUMAB IN THE ALZHEIMER's DISEASE BRAIN Alzheimer's & Dementia. 13: P282-P282. DOI: 10.1016/J.Jalz.2017.06.176  0.336
2016 Ultsch M, Li B, Maurer T, Mathieu M, Adolfsson O, Muhs A, Pfeifer A, Pihlgren M, Bainbridge TW, Reichelt M, Ernst JA, Eigenbrot C, Fuh G, Atwal JK, Watts RJ, et al. Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin. Scientific Reports. 6: 39374. PMID 27996029 DOI: 10.1038/Srep39374  0.309
2016 Lee SH, Le Pichon CE, Adolfsson O, Gafner V, Pihlgren M, Lin H, Solanoy H, Brendza R, Ngu H, Foreman O, Chan R, Ernst JA, DiCara D, Hotzel I, Srinivasan K, ... ... Atwal J, et al. Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement. Cell Reports. PMID 27475227 DOI: 10.1016/J.Celrep.2016.06.099  0.388
2016 Gadkar K, Yadav DB, Zuchero JY, Couch JA, Kanodia J, Kenrick MK, Atwal JK, Dennis MS, Prabhu S, Watts RJ, Joseph SB, Ramanujan S. Mathematical PKPD and safety model of bispecific TfR/BACE1 antibodies for the optimization of antibody uptake in brain. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 26820920 DOI: 10.1016/J.Ejpb.2016.01.009  0.302
2015 Lee S, Le Pichon C, Adolfsson O, Gafner V, Pihlgren M, Lin H, Solanoy H, Brendza R, Ngu H, Foreman O, Chan R, Ernst J, Dicara D, Hotzel I, Srinivasan K, ... ... Atwal J, et al. P2-054: Tau antibodies lacking effector function minimize inflammatory responses while effectively blocking spread of tau pathology Alzheimer's & Dementia. 11: P503-P504. DOI: 10.1016/J.Jalz.2015.06.591  0.355
2014 Wetzel-Smith MK, Hunkapiller J, Bhangale TR, Srinivasan K, Maloney JA, Atwal JK, Sa SM, Yaylaoglu MB, Foreman O, Ortmann W, Rathore N, Hansen DV, Tessier-Lavigne M, Mayeux R, et al. A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death. Nature Medicine. 20: 1452-7. PMID 25419706 DOI: 10.1038/Nm.3736  0.408
2014 Yu YJ, Atwal JK, Zhang Y, Tong RK, Wildsmith KR, Tan C, Bien-Ly N, Hersom M, Maloney JA, Meilandt WJ, Bumbaca D, Gadkar K, Hoyte K, Luk W, Lu Y, et al. Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates. Science Translational Medicine. 6: 261ra154. PMID 25378646 DOI: 10.1126/Scitranslmed.3009835  0.302
2014 Maloney JA, Bainbridge T, Gustafson A, Zhang S, Kyauk R, Steiner P, van der Brug M, Liu Y, Ernst JA, Watts RJ, Atwal JK. Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein. The Journal of Biological Chemistry. 289: 30990-1000. PMID 25253696 DOI: 10.1074/Jbc.M114.589069  0.341
2011 Yu YJ, Zhang Y, Kenrick M, Hoyte K, Luk W, Lu Y, Atwal J, Elliott JM, Prabhu S, Watts RJ, Dennis MS. Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target. Science Translational Medicine. 3: 84ra44. PMID 21613623 DOI: 10.1126/Scitranslmed.3002230  0.314
2011 Atwal JK, Chen Y, Chiu C, Mortensen DL, Meilandt WJ, Liu Y, Heise CE, Hoyte K, Luk W, Lu Y, Peng K, Wu P, Rouge L, Zhang Y, Lazarus RA, et al. A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo. Science Translational Medicine. 3: 84ra43. PMID 21613622 DOI: 10.1126/Scitranslmed.3002254  0.365
2009 Watts RJ, Chen M, Atwal J, Greve JM, Wu Y, Mortensen DL, Varisco Y, Aldolfsson O, Pihlgren M, Pfeifer A, Muhs A. P3-283: Selection of an anti-Abeta antibody that binds various forms of Abeta and blocks toxicity both in vitro and in vivo Alzheimer's & Dementia. 5: P426-P426. DOI: 10.1016/J.Jalz.2009.04.954  0.343
2008 Atwal JK, Pinkston-Gosse J, Syken J, Stawicki S, Wu Y, Shatz C, Tessier-Lavigne M. PirB is a functional receptor for myelin inhibitors of axonal regeneration. Science (New York, N.Y.). 322: 967-70. PMID 18988857 DOI: 10.1126/Science.1161151  0.302
2006 Karunakaran DKP, Sadleir KR, Kemal S, Cuddy LK, Watts R, Atwal J, Vassar RJ. P1-163: MOLECULAR MECHANISMS OF THE ALZHEIMER'S RISK GENE UNC5C IN NEURONAL DEATH Alzheimer's & Dementia. 14: P340-P340. DOI: 10.1016/J.Jalz.2018.06.167  0.458
2005 Jacobs WB, Govoni G, Ho D, Atwal JK, Barnabe-Heider F, Keyes WM, Mills AA, Miller FD, Kaplan DR. p63 is an essential proapoptotic protein during neural development. Neuron. 48: 743-56. PMID 16337913 DOI: 10.1016/J.Neuron.2005.10.027  0.632
2005 Zheng B, Atwal J, Ho C, Case L, He XL, Garcia KC, Steward O, Tessier-Lavigne M. Genetic deletion of the Nogo receptor does not reduce neurite inhibition in vitro or promote corticospinal tract regeneration in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 1205-10. PMID 15647357 DOI: 10.1073/Pnas.0409026102  0.329
2003 Atwal JK, Singh KK, Tessier-Lavigne M, Miller FD, Kaplan DR. Semaphorin 3F antagonizes neurotrophin-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase signaling: a mechanism for growth cone collapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7602-9. PMID 12930799 DOI: 10.1523/Jneurosci.23-20-07602.2003  0.463
2000 Atwal JK, Massie B, Miller FD, Kaplan DR. The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase. Neuron. 27: 265-77. PMID 10985347 DOI: 10.1016/S0896-6273(00)00035-0  0.582
2000 Kaplan D, Zirrgiebel U, Atwal J. Center stage for NGF in peripheral (but not central) sensory neuron outgrowth. Neuron. 25: 253-254. PMID 10719878 DOI: 10.1016/S0896-6273(00)80887-9  0.381
1998 Aloyz RS, Bamji SX, Pozniak CD, Toma JG, Atwal J, Kaplan DR, Miller FD. p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors. The Journal of Cell Biology. 143: 1691-703. PMID 9852160 DOI: 10.1083/Jcb.143.6.1691  0.574
1996 Slack RS, Belliveau DJ, Rosenberg M, Atwal J, Lochmüller H, Aloyz R, Haghighi A, Lach B, Seth P, Cooper E, Miller FD. Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons. The Journal of Cell Biology. 135: 1085-96. PMID 8922388 DOI: 10.1083/Jcb.135.4.1085  0.666
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