Alain Gardier - Publications

Affiliations: 
Univ. Paris Sud 

126 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Pham TH, Gardier AM. Fast-acting antidepressant activity of ketamine: highlights on brain serotonin, glutamate, and GABA neurotransmission in preclinical studies. Pharmacology & Therapeutics. PMID 30851296 DOI: 10.1016/j.pharmthera.2019.02.017  0.4
2018 Felice D, Guilloux JP, Pehrson A, Li Y, Mendez-David I, Gardier AM, Sanchez C, David DJ. Vortioxetine Improves Context Discrimination in Mice Through a Neurogenesis Independent Mechanism. Frontiers in Pharmacology. 9: 204. PMID 29593535 DOI: 10.3389/fphar.2018.00204  1
2018 Defaix C, Solgadi A, Pham TH, Gardier AM, Chaminade P, Tritschler L. Rapid analysis of glutamate, glutamine and GABA in mice frontal cortex microdialysis samples using HPLC coupled to electrospray tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 152: 31-38. PMID 29414016 DOI: 10.1016/j.jpba.2018.01.039  1
2017 Tritschler L, Kheirbek MA, Dantec YL, Mendez-David I, Guilloux JP, Faye C, Doan J, Pham TH, Hen R, David DJ, Gardier AM. Optogenetic activation of granule cells in the dorsal dentate gyrus enhances dopaminergic neurotransmission in the Nucleus Accumbens. Neuroscience Research. PMID 29246683 DOI: 10.1016/j.neures.2017.12.002  1
2017 Pham TH, Defaix C, Xu X, Deng SX, Fabresse N, Alvarez JC, Landry DW, Brachman RA, Denny CA, Gardier AM. Common Neurotransmission Recruited in (R,S)-Ketamine and (2R,6R)-Hydroxynorketamine-Induced Sustained Antidepressant-like Effects. Biological Psychiatry. PMID 29174592 DOI: 10.1016/j.biopsych.2017.10.020  0.4
2017 Petit AC, El Asmar K, David DJ, Gardier AM, Becquemont L, Fève B, Verstuyft C, Corruble E. The association of β-arrestin2 polymorphisms with response to antidepressant treatment in depressed patients. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 29031912 DOI: 10.1016/j.pnpbp.2017.10.006  1
2017 Mendez-David I, Boursier C, Domergue V, Colle R, Falissard B, Corruble E, Gardier AM, Guilloux JP, David DJ. Differential Peripheral Proteomic Biosignature of Fluoxetine Response in a Mouse Model of Anxiety/Depression. Frontiers in Cellular Neuroscience. 11: 237. PMID 28860968 DOI: 10.3389/fncel.2017.00237  1
2017 Mendez-David I, Guilloux JP, Papp M, Tritschler L, Mocaer E, Gardier AM, Bretin S, David DJ. S 47445 Produces Antidepressant- and Anxiolytic-Like Effects through Neurogenesis Dependent and Independent Mechanisms. Frontiers in Pharmacology. 8: 462. PMID 28769796 DOI: 10.3389/fphar.2017.00462  1
2017 Mekiri M, Gardier AM, David DJ, Guilloux JP. Chronic Corticosterone Administration Effects on Behavioral Emotionality in Female C57BL6 Mice. Experimental and Clinical Psychopharmacology. PMID 28287792 DOI: 10.1037/pha0000112  1
2017 Guilloux JP, Samuels BA, Mendez-David I, Hu A, Levinstein M, Faye C, Mekiri M, Mocaer E, Gardier AM, Hen R, Sors A, David DJ. S 38093, a histamine H3 antagonist/inverse agonist, promotes hippocampal neurogenesis and improves context discrimination task in aged mice. Scientific Reports. 7: 42946. PMID 28218311 DOI: 10.1038/srep42946  1
2017 Garcia-Garcia AL, Meng Q, Canetta S, Gardier AM, Guiard BP, Kellendonk C, Dranovsky A, Leonardo ED. Serotonin Signaling through Prefrontal Cortex 5-HT1A Receptors during Adolescence Can Determine Baseline Mood-Related Behaviors. Cell Reports. 18: 1144-1156. PMID 28147271 DOI: 10.1016/j.celrep.2017.01.021  1
2017 Pham TH, Mendez-David I, Defaix C, Guiard BP, Tritschler L, David DJ, Gardier AM. Ketamine treatment involves medial prefrontal cortex serotonin to induce a rapid antidepressant-like activity in BALB/cJ mice. Neuropharmacology. 112: 198-209. PMID 27211253 DOI: 10.1016/j.neuropharm.2016.05.010  1
2016 Besson M, Guiducci S, Granon S, Guilloux JP, Guiard B, Repérant C, Faure P, Pons S, Cannazza G, Zoli M, Gardier AM, Maskos U. Alterations in alpha5* nicotinic acetylcholine receptors result in midbrain- and hippocampus-dependent behavioural and neural impairments. Psychopharmacology. 233: 3297-314. PMID 27385416 DOI: 10.1007/s00213-016-4362-2  0.92
2016 Nautiyal KM, Tritschler L, Ahmari SE, David DJ, Gardier AM, Hen R. A Lack of Serotonin 1B Autoreceptors Results in Decreased Anxiety and Depression-Related Behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 41: 2941-2950. PMID 27353308 DOI: 10.1038/npp.2016.109  1
2016 David DJ, Gardier AM. [The pharmacological basis of the serotonin system: Application to antidepressant response]. L'Encephale. 42: 255-63. PMID 27112704 DOI: 10.1016/j.encep.2016.03.012  1
2016 Darcet F, Gardier AM, Gaillard R, David DJ, Guilloux JP. Cognitive Dysfunction in Major Depressive Disorder. A Translational Review in Animal Models of the Disease. Pharmaceuticals (Basel, Switzerland). 9. PMID 26901205 DOI: 10.3390/ph9010009  1
2016 David DJ, Tritschler L, Guilloux JP, Gardier AM, Sanchez C, Gaillard R. [Pharmacological properties of vortioxetine and its pre-clinical consequences]. L'Encephale. 42: 1S12-23. PMID 26879252 DOI: 10.1016/S0013-7006(16)30015-X  1
2016 Darcet F, Gardier AM, David DJ, Guilloux JP. Chronic 5-HT4 receptor agonist treatment restores learning and memory deficits in a neuroendocrine mouse model of anxiety/depression. Neuroscience Letters. 616: 197-203. PMID 26850572 DOI: 10.1016/j.neulet.2016.01.055  1
2016 Qesseveur G, Petit AC, Nguyen HT, Dahan L, Colle R, Rotenberg S, Seif I, Robert P, David D, Guilloux JP, Gardier AM, Verstuyft C, Becquemont L, Corruble E, Guiard BP. Genetic dysfunction of serotonin 2A receptor hampers response to antidepressant drugs: A translational approach. Neuropharmacology. 105: 142-53. PMID 26764241 DOI: 10.1016/j.neuropharm.2015.12.022  1
2016 Brachman RA, McGowan JC, Perusini JN, Lim SC, Pham TH, Faye C, Gardier AM, Mendez-David I, David DJ, Hen R, Denny CA. Ketamine as a Prophylactic Against Stress-Induced Depressive-like Behavior. Biological Psychiatry. 79: 776-86. PMID 26037911 DOI: 10.1016/j.biopsych.2015.04.022  1
2016 Samuels BA, Mendez-David I, Faye C, David SA, Pierz KA, Gardier AM, Hen R, David DJ. Serotonin 1A and Serotonin 4 Receptors: Essential Mediators of the Neurogenic and Behavioral Actions of Antidepressants. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 22: 26-45. PMID 25488850 DOI: 10.1177/1073858414561303  1
2015 Schloesser RJ, Orvoen S, Jimenez DV, Hardy NF, Maynard KR, Sukumar M, Manji HK, Gardier AM, David DJ, Martinowich K. Antidepressant-like Effects of Electroconvulsive Seizures Require Adult Neurogenesis in a Neuroendocrine Model of Depression. Brain Stimulation. 8: 862-7. PMID 26138027 DOI: 10.1016/j.brs.2015.05.011  1
2015 Felice D, O'Leary OF, Cryan JF, Dinan TG, Gardier AM, Sánchez C, David DJ. When ageing meets the blues: Are current antidepressants effective in depressed aged patients? Neuroscience and Biobehavioral Reviews. 55: 478-97. PMID 26054791 DOI: 10.1016/j.neubiorev.2015.06.005  1
2015 Mendez-David I, Tritschler L, Ali ZE, Damiens MH, Pallardy M, David DJ, Kerdine-Römer S, Gardier AM. Nrf2-signaling and BDNF: A new target for the antidepressant-like activity of chronic fluoxetine treatment in a mouse model of anxiety/depression. Neuroscience Letters. 597: 121-6. PMID 25916883 DOI: 10.1016/j.neulet.2015.04.036  1
2015 Nautiyal KM, Tanaka KF, Barr MM, Tritschler L, Le Dantec Y, David DJ, Gardier AM, Blanco C, Hen R, Ahmari SE. Distinct Circuits Underlie the Effects of 5-HT1B Receptors on Aggression and Impulsivity. Neuron. 86: 813-26. PMID 25892302 DOI: 10.1016/j.neuron.2015.03.041  1
2015 Couroussé T, Bacq A, Belzung C, Guiard B, Balasse L, Louis F, Le Guisquet AM, Gardier AM, Schinkel AH, Giros B, Gautron S. Brain organic cation transporter 2 controls response and vulnerability to stress and GSK3β signaling. Molecular Psychiatry. 20: 889-900. PMID 25092247 DOI: 10.1038/mp.2014.86  1
2015 Hache G, Guiard BP, Nguyen TH, Quesseveur G, Gardier AM, Peters D, Munro G, Coudoré F. Antinociceptive activity of the new triple reuptake inhibitor NS18283 in a mouse model of chemotherapy-induced neuropathic pain. European Journal of Pain (London, England). 19: 322-33. PMID 25045036 DOI: 10.1002/ejp.550  1
2015 Mendez-David I, David DJ, Guilloux JP, Hen R, Gardier AM. 5-ht4 receptor subtype, β-arrestin level, and rapid-onset effects of antidepressant drugs Neuromethods. 95: 101-121. DOI: 10.1007/978-1-4939-2187-4_6  1
2014 Tritschler L, Felice D, Colle R, Guilloux JP, Corruble E, Gardier AM, David DJ. Vortioxetine for the treatment of major depressive disorder. Expert Review of Clinical Pharmacology. 7: 731-45. PMID 25166025 DOI: 10.1586/17512433.2014.950655  1
2014 Darcet F, Mendez-David I, Tritschler L, Gardier AM, Guilloux JP, David DJ. Learning and memory impairments in a neuroendocrine mouse model of anxiety/depression. Frontiers in Behavioral Neuroscience. 8: 136. PMID 24822041 DOI: 10.3389/fnbeh.2014.00136  1
2014 Petit AC, Quesseveur G, Gressier F, Colle R, David DJ, Gardier AM, Ferreri F, Lépine JP, Falissard B, Verstuyft C, Guiard BP, Corruble E. Converging translational evidence for the involvement of the serotonin 2A receptor gene in major depressive disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 54: 76-82. PMID 24801750 DOI: 10.1016/j.pnpbp.2014.04.013  1
2014 Mendez-David I, David DJ, Darcet F, Wu MV, Kerdine-Römer S, Gardier AM, Hen R. Rapid anxiolytic effects of a 5-HT₄ receptor agonist are mediated by a neurogenesis-independent mechanism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1366-78. PMID 24287720 DOI: 10.1038/npp.2013.332  1
2014 Brachman RA, McGowan JC, Perusini JN, Lim SC, Pham TH, Faye C, Gardier AM, Mendez-David I, David DJ, Hen R, Denny CA. Ketamine as a Prophylactic Against Stress-Induced Depressive-Like Behavior Biological Psychiatry. DOI: 10.1016/j.biopsych.2015.04.022  1
2013 Mendez-David I, El-Ali Z, Hen R, Falissard B, Corruble E, Gardier AM, Kerdine-Römer S, David DJ. A method for biomarker measurements in peripheral blood mononuclear cells isolated from anxious and depressed mice: β-arrestin 1 protein levels in depression and treatment. Frontiers in Pharmacology. 4: 124. PMID 24133448 DOI: 10.3389/fphar.2013.00124  1
2013 Quesseveur G, Gardier AM, Guiard BP. The monoaminergic tripartite synapse: a putative target for currently available antidepressant drugs. Current Drug Targets. 14: 1277-94. PMID 24020973  1
2013 Pla P, Orvoen S, Benstaali C, Dodier S, Gardier AM, David DJ, Humbert S, Saudou F. Huntingtin acts non cell-autonomously on hippocampal neurogenesis and controls anxiety-related behaviors in adult mouse. Plos One. 8: e73902. PMID 24019939 DOI: 10.1371/journal.pone.0073902  1
2013 Guilloux JP, Mendez-David I, Pehrson A, Guiard BP, Repérant C, Orvoën S, Gardier AM, Hen R, Ebert B, Miller S, Sanchez C, David DJ. Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice. Neuropharmacology. 73: 147-59. PMID 23721744 DOI: 10.1016/j.neuropharm.2013.05.014  1
2013 Ben M'Barek K, Pla P, Orvoen S, Benstaali C, Godin JD, Gardier AM, Saudou F, David DJ, Humbert S. Huntingtin mediates anxiety/depression-related behaviors and hippocampal neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 8608-20. PMID 23678106 DOI: 10.1523/JNEUROSCI.5110-12.2013  1
2013 Quesseveur G, David DJ, Gaillard MC, Pla P, Wu MV, Nguyen HT, Nicolas V, Auregan G, David I, Dranovsky A, Hantraye P, Hen R, Gardier AM, Déglon N, Guiard BP. BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities. Translational Psychiatry. 3: e253. PMID 23632457 DOI: 10.1038/tp.2013.30  1
2013 Mendez-David I, Hen R, Gardier AM, David DJ. Adult hippocampal neurogenesis: an actor in the antidepressant-like action. Annales Pharmaceutiques Francaises. 71: 143-9. PMID 23622692 DOI: 10.1016/j.pharma.2013.02.006  1
2013 Quesseveur G, Repérant C, David DJ, Gardier AM, Sanchez C, Guiard BP. 5-HT₂A receptor inactivation potentiates the acute antidepressant-like activity of escitalopram: involvement of the noradrenergic system. Experimental Brain Research. 226: 285-95. PMID 23411676 DOI: 10.1007/s00221-013-3434-3  1
2013 Tolu S, Eddine R, Marti F, David V, Graupner M, Pons S, Baudonnat M, Husson M, Besson M, Reperant C, Zemdegs J, Pagès C, Hay YA, Lambolez B, Caboche J, ... ... Gardier AM, et al. Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement. Molecular Psychiatry. 18: 382-93. PMID 22751493 DOI: 10.1038/mp.2012.83  1
2013 Nguyen HT, Guiard BP, Bacq A, David DJ, David I, Quesseveur G, Gautron S, Sanchez C, Gardier AM. Blockade of the high-affinity noradrenaline transporter (NET) by the selective 5-HT reuptake inhibitor escitalopram: an in vivo microdialysis study in mice. British Journal of Pharmacology. 168: 103-16. PMID 22233336 DOI: 10.1111/j.1476-5381.2012.01850.x  1
2012 Quesseveur G, Nguyen HT, Gardier AM, Guiard BP. 5-HT2 ligands in the treatment of anxiety and depression. Expert Opinion On Investigational Drugs. 21: 1701-25. PMID 22917059 DOI: 10.1517/13543784.2012.719872  1
2012 Xia L, Deloménie C, David I, Rainer Q, Marouard M, Delacroix H, David DJ, Gardier AM, Guilloux JP. Ventral hippocampal molecular pathways and impaired neurogenesis associated with 5-HT₁A and 5-HT₁B receptors disruption in mice. Neuroscience Letters. 521: 20-5. PMID 22622174 DOI: 10.1016/j.neulet.2012.05.046  1
2012 Hache G, Guiard BP, Le Dantec Y, Orvoën S, David DJ, Gardier AM, Coudoré F. Antinociceptive effects of fluoxetine in a mouse model of anxiety/depression. Neuroreport. 23: 525-9. PMID 22555563 DOI: 10.1097/WNR.0b013e328353d70a  1
2012 Orvoen S, Pla P, Gardier AM, Saudou F, David DJ. Huntington's disease knock-in male mice show specific anxiety-like behaviour and altered neuronal maturation. Neuroscience Letters. 507: 127-32. PMID 22178857 DOI: 10.1016/j.neulet.2011.11.063  1
2012 Rainer Q, Nguyen HT, Quesseveur G, Gardier AM, David DJ, Guiard BP. Functional status of somatodendritic serotonin 1A autoreceptor after long-term treatment with fluoxetine in a mouse model of anxiety/depression based on repeated corticosterone administration. Molecular Pharmacology. 81: 106-12. PMID 22031471 DOI: 10.1124/mol.111.075796  1
2012 Guilloux JP, Douillard-Guilloux G, Kota R, Wang X, Gardier AM, Martinowich K, Tseng GC, Lewis DA, Sibille E. Molecular evidence for BDNF- and GABA-related dysfunctions in the amygdala of female subjects with major depression. Molecular Psychiatry. 17: 1130-42. PMID 21912391 DOI: 10.1038/mp.2011.113  1
2012 Besson M, David V, Baudonnat M, Cazala P, Guilloux JP, Reperant C, Cloez-Tayarani I, Changeux JP, Gardier AM, Granon S. Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice. Psychopharmacology. 220: 1-14. PMID 21901321 DOI: 10.1007/s00213-011-2422-1  0.92
2012 Bacq A, Balasse L, Biala G, Guiard B, Gardier AM, Schinkel A, Louis F, Vialou V, Martres MP, Chevarin C, Hamon M, Giros B, Gautron S. Organic cation transporter 2 controls brain norepinephrine and serotonin clearance and antidepressant response. Molecular Psychiatry. 17: 926-39. PMID 21769100 DOI: 10.1038/mp.2011.87  1
2012 Rainer Q, Xia L, Guilloux JP, Gabriel C, Mocaër E, Hen R, Enhamre E, Gardier AM, David DJ. Beneficial behavioural and neurogenic effects of agomelatine in a model of depression/anxiety. The International Journal of Neuropsychopharmacology. 15: 321-35. PMID 21473810 DOI: 10.1017/S1461145711000356  1
2011 Richardson-Jones JW, Craige CP, Nguyen TH, Kung HF, Gardier AM, Dranovsky A, David DJ, Guiard BP, Beck SG, Hen R, Leonardo ED. Serotonin-1A autoreceptors are necessary and sufficient for the normal formation of circuits underlying innate anxiety. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6008-18. PMID 21508226 DOI: 10.1523/JNEUROSCI.5836-10.2011  1
2011 Samuels BA, Leonardo ED, Gadient R, Williams A, Zhou J, David DJ, Gardier AM, Wong EH, Hen R. Modeling treatment-resistant depression. Neuropharmacology. 61: 408-13. PMID 21356220 DOI: 10.1016/j.neuropharm.2011.02.017  1
2011 Guilloux JP, David DJ, Xia L, Nguyen HT, Rainer Q, Guiard BP, Repérant C, Deltheil T, Toth M, Hen R, Gardier AM. Characterization of 5-HT(1A/1B)-/- mice: an animal model sensitive to anxiolytic treatments. Neuropharmacology. 61: 478-88. PMID 21333660 DOI: 10.1016/j.neuropharm.2011.02.009  1
2011 Hache G, Coudore F, Gardier AM, Guiard BP. Monoaminergic antidepressants in the relief of pain: Potential therapeutic utility of triple reuptake inhibitors (TRIs) Pharmaceuticals. 4: 285-342. DOI: 10.3390/ph4020285  1
2010 David DJ, Wang J, Samuels BA, Rainer Q, David I, Gardier AM, Hen R. Implications of the functional integration of adult-born hippocampal neurons in anxiety-depression disorders. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 16: 578-91. PMID 20889967 DOI: 10.1177/1073858409360281  1
2010 Richardson-Jones JW, Craige CP, Guiard BP, Stephen A, Metzger KL, Kung HF, Gardier AM, Dranovsky A, David DJ, Beck SG, Hen R, Leonardo ED. 5-HT1A autoreceptor levels determine vulnerability to stress and response to antidepressants. Neuron. 65: 40-52. PMID 20152112 DOI: 10.1016/j.neuron.2009.12.003  1
2010 Amilhon B, Lepicard E, Renoir T, Mongeau R, Popa D, Poirel O, Miot S, Gras C, Gardier AM, Gallego J, Hamon M, Lanfumey L, Gasnier B, Giros B, El Mestikawy S. VGLUT3 (vesicular glutamate transporter type 3) contribution to the regulation of serotonergic transmission and anxiety. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2198-210. PMID 20147547 DOI: 10.1523/JNEUROSCI.5196-09.2010  0.52
2010 Popa D, Cerdan J, Repérant C, Guiard BP, Guilloux JP, David DJ, Gardier AM. A longitudinal study of 5-HT outflow during chronic fluoxetine treatment using a new technique of chronic microdialysis in a highly emotional mouse strain. European Journal of Pharmacology. 628: 83-90. PMID 19944680 DOI: 10.1016/j.ejphar.2009.11.037  1
2010 Reperant C, Pons S, Dufour E, Rollema H, Gardier AM, Maskos U. Effect of the alpha4beta2* nicotinic acetylcholine receptor partial agonist varenicline on dopamine release in beta2 knock-out mice with selective re-expression of the beta2 subunit in the ventral tegmental area. Neuropharmacology. 58: 346-50. PMID 19887076 DOI: 10.1016/j.neuropharm.2009.10.007  0.52
2009 Rainer Q, Gardier AM, Hen R, David DJ. [Neurogenesis-dependent and independent effects of anti-depressant drugs]. Medecine Sciences : M/S. 25: 795-8. PMID 19849978 DOI: 10.1051/medsci/20092510795  1
2009 David DJ, Samuels BA, Rainer Q, Wang JW, Marsteller D, Mendez I, Drew M, Craig DA, Guiard BP, Guilloux JP, Artymyshyn RP, Gardier AM, Gerald C, Antonijevic IA, Leonardo ED, et al. Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. Neuron. 62: 479-93. PMID 19477151 DOI: 10.1016/j.neuron.2009.04.017  1
2009 Gardier AM, Guiard BP, Guilloux JP, Repérant C, Coudoré F, David DJ. Interest of using genetically manipulated mice as models of depression to evaluate antidepressant drugs activity: a review. Fundamental & Clinical Pharmacology. 23: 23-42. PMID 19267769 DOI: 10.1111/j.1472-8206.2008.00640.x  1
2009 Deltheil T, Tanaka K, Reperant C, Hen R, David DJ, Gardier AM. Synergistic neurochemical and behavioural effects of acute intrahippocampal injection of brain-derived neurotrophic factor and antidepressants in adult mice. The International Journal of Neuropsychopharmacology. 12: 905-15. PMID 19236729 DOI: 10.1017/S1461145709000017  1
2008 Chenu F, David DJ, Leroux-Nicollet I, Le Maître E, Gardier AM, Bourin M. Serotonin1B heteroreceptor activation induces an antidepressant-like effect in mice with an alteration of the serotonergic system. Journal of Psychiatry & Neuroscience : Jpn. 33: 541-50. PMID 18982177  1
2008 Avale ME, Faure P, Pons S, Robledo P, Deltheil T, David DJ, Gardier AM, Maldonado R, Granon S, Changeux JP, Maskos U. Interplay of beta2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion. Proceedings of the National Academy of Sciences of the United States of America. 105: 15991-6. PMID 18832468 DOI: 10.1073/pnas.0807635105  1
2008 Deltheil T, Guiard BP, Cerdan J, David DJ, Tanaka KF, Repérant C, Guilloux JP, Coudoré F, Hen R, Gardier AM. Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice. Neuropharmacology. 55: 1006-14. PMID 18761360 DOI: 10.1016/j.neuropharm.2008.08.001  1
2008 Benmansour S, Deltheil T, Piotrowski J, Nicolas L, Reperant C, Gardier AM, Frazer A, David DJ. Influence of brain-derived neurotrophic factor (BDNF) on serotonin neurotransmission in the hippocampus of adult rodents. European Journal of Pharmacology. 587: 90-8. PMID 18474368 DOI: 10.1016/j.ejphar.2008.03.048  1
2008 Cachard-Chastel M, Devers S, Sicsic S, Langlois M, Lezoualc'h F, Gardier AM, Belzung C. Prucalopride and donepezil act synergistically to reverse scopolamine-induced memory deficit in C57Bl/6j mice. Behavioural Brain Research. 187: 455-61. PMID 18061284 DOI: 10.1016/j.bbr.2007.10.008  1
2008 Deltheil T, Guiard BP, Guilloux JP, Nicolas L, Deloménie C, Repérant C, Le Maitre E, Leroux-Nicollet I, Benmansour S, Coudoré F, David DJ, Gardier AM. Consequences of changes in BDNF levels on serotonin neurotransmission, 5-HT transporter expression and function: studies in adult mice hippocampus. Pharmacology, Biochemistry, and Behavior. 90: 174-83. PMID 17980409 DOI: 10.1016/j.pbb.2007.09.018  1
2008 Guiard BP, David DJ, Deltheil T, Chenu F, Le Maître E, Renoir T, Leroux-Nicollet I, Sokoloff P, Lanfumey L, Hamon M, Andrews AM, Hen R, Gardier AM. Brain-derived neurotrophic factor-deficient mice exhibit a hippocampal hyperserotonergic phenotype. The International Journal of Neuropsychopharmacology. 11: 79-92. PMID 17559709 DOI: 10.1017/S1461145707007857  1
2007 Guiard BP, Guilloux JP, Reperant C, Hunt SP, Toth M, Gardier AM. Substance P neurokinin 1 receptor activation within the dorsal raphe nucleus controls serotonin release in the mouse frontal cortex. Molecular Pharmacology. 72: 1411-8. PMID 17890358 DOI: 10.1124/mol.107.040113  1
2007 Jacquot C, David DJ, Gardier AM, Sánchez C. [Escitalopram and citalopram: the unexpected role of the R-enantiomer]. L'Encephale. 33: 179-87. PMID 17675913  1
2007 Cachard-Chastel M, Lezoualc'h F, Dewachter I, Deloménie C, Croes S, Devijver H, Langlois M, Van Leuven F, Sicsic S, Gardier AM. 5-HT4 receptor agonists increase sAPPalpha levels in the cortex and hippocampus of male C57BL/6j mice. British Journal of Pharmacology. 150: 883-92. PMID 17325649 DOI: 10.1038/sj.bjp.0707178  1
2006 Molles BE, Maskos U, Pons S, Besson M, Guiard P, Guilloux JP, Evrard A, Cormier A, Mameli-Engvall M, Cloëz-Tayarani I, Nakatani H, Dufour N, Bemelmans AP, Mallet J, Cazala P, ... Gardier AM, et al. Targeted in vivo expression of nicotinic acetylcholine receptors in mouse brain using lentiviral expression vectors. Journal of Molecular Neuroscience : Mn. 30: 105-6. PMID 17192649 DOI: 10.1385/JMN:30:1:105  1
2006 Chenu F, Guiard BP, Bourin M, Gardier AM. Antidepressant-like activity of selective serotonin reuptake inhibitors combined with a NK1 receptor antagonist in the mouse forced swimming test. Behavioural Brain Research. 172: 256-63. PMID 16806519 DOI: 10.1016/j.bbr.2006.05.011  1
2006 Guiard BP, Lanfumey L, Gardier AM. Microdialysis approach to study serotonin outflow in mice following selective serotonin reuptake inhibitors and substance P (neurokinin 1) receptor antagonist administration: a review. Current Drug Targets. 7: 187-201. PMID 16475960  1
2006 Guilloux JP, David DJ, Guiard BP, Chenu F, Repérant C, Toth M, Bourin M, Gardier AM. Blockade of 5-HT1A receptors by (+/-)-pindolol potentiates cortical 5-HT outflow, but not antidepressant-like activity of paroxetine: microdialysis and behavioral approaches in 5-HT1A receptor knockout mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2162-72. PMID 16452992 DOI: 10.1038/sj.npp.1301019  1
2005 Guiard BP, Froger N, Hamon M, Gardier AM, Lanfumey L. Sustained pharmacological blockade of NK1 substance P receptors causes functional desensitization of dorsal raphe 5-HT 1A autoreceptors in mice. Journal of Neurochemistry. 95: 1713-23. PMID 16219031 DOI: 10.1111/j.1471-4159.2005.03488.x  1
2005 Maskos U, Molles BE, Pons S, Besson M, Guiard BP, Guilloux JP, Evrard A, Cazala P, Cormier A, Mameli-Engvall M, Dufour N, Cloëz-Tayarani I, Bemelmans AP, Mallet J, Gardier AM, et al. Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors. Nature. 436: 103-7. PMID 16001069 DOI: 10.1038/nature03694  1
2004 Bert L, Favale D, Jego G, Greve P, Guilloux JP, Guiard BP, Gardier AM, Suaud-Chagny MF, Lestage P. Rapid and precise method to locate microdialysis probe implantation in the rodent brain. Journal of Neuroscience Methods. 140: 53-7. PMID 15589334 DOI: 10.1016/j.jneumeth.2004.04.042  1
2004 David DJ, Froger N, Guiard B, Przybylski C, Jego G, Boni C, Hunt SP, De Felipe C, Hamon M, Jacquot C, Gardier AM, Lanfumey L. Serotonin transporter in substance P (neurokinin 1) receptor knock-out mice. European Journal of Pharmacology. 492: 41-8. PMID 15145704 DOI: 10.1016/j.ejphar.2004.03.016  1
2004 Guiard BP, Przybylski C, Guilloux JP, Seif I, Froger N, De Felipe C, Hunt SP, Lanfumey L, Gardier AM. Blockade of substance P (neurokinin 1) receptors enhances extracellular serotonin when combined with a selective serotonin reuptake inhibitor: an in vivo microdialysis study in mice. Journal of Neurochemistry. 89: 54-63. PMID 15030389 DOI: 10.1046/j.1471-4159.2003.02304.x  1
2003 David DJ, Bourin M, Jego G, Przybylski C, Jolliet P, Gardier AM. Effects of acute treatment with paroxetine, citalopram and venlafaxine in vivo on noradrenaline and serotonin outflow: a microdialysis study in Swiss mice. British Journal of Pharmacology. 140: 1128-36. PMID 14530210 DOI: 10.1038/sj.bjp.0705538  1
2003 Champtiaux N, Gotti C, Cordero-Erausquin M, David DJ, Przybylski C, Léna C, Clementi F, Moretti M, Rossi FM, Le Novère N, McIntosh JM, Gardier AM, Changeux JP. Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7820-9. PMID 12944511  1
2003 Gardier AM, David DJ, Jego G, Przybylski C, Jacquot C, Durier S, Gruwez B, Douvier E, Beauverie P, Poisson N, Hen R, Bourin M. Effects of chronic paroxetine treatment on dialysate serotonin in 5-HT1B receptor knockout mice. Journal of Neurochemistry. 86: 13-24. PMID 12807420  1
2003 Marubio LM, Gardier AM, Durier S, David D, Klink R, Arroyo-Jimenez MM, McIntosh JM, Rossi F, Champtiaux N, Zoli M, Changeux JP. Effects of nicotine in the dopaminergic system of mice lacking the alpha4 subunit of neuronal nicotinic acetylcholine receptors. The European Journal of Neuroscience. 17: 1329-37. PMID 12713636 DOI: 10.1046/j.1460-9568.2003.02564.x  1
2002 Bourin M, David DJ, Jolliet P, Gardier A. [Mechanism of action of antidepressants and therapeutic perspectives]. Therapie. 57: 385-96. PMID 12422559  1
2002 Malagié I, David DJ, Jolliet P, Hen R, Bourin M, Gardier AM. Improved efficacy of fluoxetine in increasing hippocampal 5-hydroxytryptamine outflow in 5-HT(1B) receptor knock-out mice. European Journal of Pharmacology. 443: 99-104. PMID 12044798  1
2002 Evrard A, Malagié I, Laporte AM, Boni C, Hanoun N, Trillat AC, Seif I, De Maeyer E, Gardier A, Hamon M, Adrien J. Altered regulation of the 5-HT system in the brain of MAO-A knock-out mice. The European Journal of Neuroscience. 15: 841-51. PMID 11906526 DOI: 10.1046/j.1460-9568.2002.01917.x  1
2001 Froger N, Gardier AM, Moratalla R, Alberti I, Lena I, Boni C, De Felipe C, Rupniak NM, Hunt SP, Jacquot C, Hamon M, Lanfumey L. 5-hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 8188-97. PMID 11588191  1
2001 Robert SJ, Zugaza JL, Fischmeister R, Gardier AM, Lezoualc'h F. The human serotonin 5-HT4 receptor regulates secretion of non-amyloidogenic precursor protein. The Journal of Biological Chemistry. 276: 44881-8. PMID 11584021 DOI: 10.1074/jbc.M109008200  1
2001 Gardier AM, Gruwez B, Trillat AC, Jacquot C, Hen R, Bourin M. Interaction between 5-HT(1A) and 5-HT(1B) receptors: effects of 8-OH-DPAT-induced hypothermia in 5-HT(1B) receptor knockout mice. European Journal of Pharmacology. 421: 171-5. PMID 11516433 DOI: 10.1016/S0014-2999(01)01037-8  1
2001 Gardier AM, Trillat AC, Malagié I, David D, Hascoët M, Colombel MC, Jolliet P, Jacquot C, Hen R, Bourin M. [5-HT1B serotonin receptors and antidepressant effects of selective serotonin reuptake inhibitors ]. Comptes Rendus De L'AcadéMie Des Sciences. SéRie Iii, Sciences De La Vie. 324: 433-41. PMID 11417564 DOI: 10.1016/S0764-4469(01)01332-4  1
2001 Rocher C, Gardier AM. Effects of repeated systemic administration of d-Fenfluramine on serotonin and glutamate release in rat ventral hippocampus: comparison with methamphetamine using in vivo microdialysis. Naunyn-Schmiedeberg's Archives of Pharmacology. 363: 422-8. PMID 11330336 DOI: 10.1007/s002100000381  1
2001 Gardier AM, Bourin M. Appropriate use of "knockout" mice as models of depression or models of testing the efficacy of antidepressants. Psychopharmacology. 153: 393-4. PMID 11271413 DOI: 10.1007/s002130000560  1
2001 Malagié I, Trillat AC, Bourin M, Jacquot C, Hen R, Gardier AM. 5-HT1B Autoreceptors limit the effects of selective serotonin re-uptake inhibitors in mouse hippocampus and frontal cortex. Journal of Neurochemistry. 76: 865-71. PMID 11158258 DOI: 10.1046/j.1471-4159.2001.00083.x  1
2000 Malagié I, Deslandes A, Gardier AM. Effects of acute and chronic tianeptine administration on serotonin outflow in rats: comparison with paroxetine by using in vivo microdialysis. European Journal of Pharmacology. 403: 55-65. PMID 10969144 DOI: 10.1016/S0014-2999(00)00486-6  1
2000 Gardier AM, Moratalla R, Cuéllar B, Sacerdote M, Guibert B, Lebrec H, Graybiel AM. Interaction between the serotoninergic and dopaminergic systems in d-fenfluramine-induced activation of c-fos and jun B genes in rat striatal neurons. Journal of Neurochemistry. 74: 1363-73. PMID 10737591 DOI: 10.1046/j.1471-4159.2000.0741363.x  1
1999 Rocher C, Jacquot C, Gardier AM. Simultaneous effects of local dexfenfluramine application on extracellular glutamate and serotonin levels in rat frontal cortex: a reverse microdialysis study. Neuropharmacology. 38: 513-23. PMID 10221755 DOI: 10.1016/S0028-3908(98)00212-3  1
1999 Wu Y, Shaghaghi EK, Jacquot C, Pallardy M, Gardier AM. Synergism between interleukin-6 and interleukin-1beta in hypothalamic serotonin release: a reverse in vivo microdialysis study in F344 rats. European Cytokine Network. 10: 57-64. PMID 10210774  1
1998 Trillat AC, Malagié I, Bourin M, Jacquot C, Hen R, Gardier AM. [Homozygote mice deficient in serotonin 5-HT1B receptor and antidepressant effect of selective serotonin reuptake inhibitors]. Comptes Rendus Des SéAnces De La SociéTé De Biologie Et De Ses Filiales. 192: 1139-47. PMID 10101609  1
1998 Trillat AC, Malagié I, Mathe-Allainmat M, Anmella MC, Jacquot C, Langlois M, Gardier AM. Synergistic neurochemical and behavioral effects of fluoxetine and 5-HT1A receptor antagonists. European Journal of Pharmacology. 357: 179-84. PMID 9797034 DOI: 10.1016/S0014-2999(98)00590-1  1
1998 Trillat AC, Malagié I, Mathé-Allainmat M, Anmela MC, Jacquot C, Langlois M, Gardier AM. Effects of WAY 100635 and (-)-5-Me-8-OH-DPAT, a novel 5-HT1A receptor antagonist, on 8-OH-DPAT responses. European Journal of Pharmacology. 347: 41-9. PMID 9650846 DOI: 10.1016/S0014-2999(98)00085-5  1
1998 Trillat AC, Mathé-Allainmat M, Brémont B, Malagié I, Jacquot C, Gardier AM, Langlois M. (-)-5-Methyl-8-hydroxy-(di-n-propylamino)tetralin: A new 5-HT(1A) receptor antagonist European Journal of Medicinal Chemistry. 33: 437-444. DOI: 10.1016/S0223-5234(98)80044-5  1
1997 Trillat AC, Malagié I, Scearce K, Pons D, Anmella MC, Jacquot C, Hen R, Gardier AM. Regulation of serotonin release in the frontal cortex and ventral hippocampus of homozygous mice lacking 5-HT1B receptors: in vivo microdialysis studies. Journal of Neurochemistry. 69: 2019-25. PMID 9349547  1
1996 Malagié I, Trillat AC, Douvier E, Anmella MC, Dessalles MC, Jacquot C, Gardier AM. Regional differences in the effect of the combined treatment of WAY 100635 and fluoxetine: an in vivo microdialysis study. Naunyn-Schmiedeberg's Archives of Pharmacology. 354: 785-90. PMID 8971740  1
1996 Rocher C, Bert L, Robert F, Trouvin JH, Renaud B, Jacquot C, Gardier AM. Microdialysis monitoring of variations in extracellular levels of serotonin, GABA and excitatory amino acids in the frontal cortex of awake rats in response to a single peripheral or central administration of dexfenfluramine. Brain Research. 737: 221-30. PMID 8930369 DOI: 10.1016/0006-8993(96)00735-4  1
1996 Gardier AM, Malagié I, Trillat AC, Jacquot C, Artigas F. Role of 5-HT1A autoreceptors in the mechanism of action of serotoninergic antidepressant drugs: recent findings from in vivo microdialysis studies. Fundamental & Clinical Pharmacology. 10: 16-27. PMID 8900496  1
1995 Parsadaniantz SM, Gaillet S, Malaval F, Lenoir V, Batsche E, Barbanel G, Gardier A, Terlain B, Jacquot C, Szafarczyk A. Lesions of the afferent catecholaminergic pathways inhibit the temporal activation of the CRH and POMC gene expression and ACTH release induced by human interleukin-1beta in the male rat. Neuroendocrinology. 62: 586-95. PMID 8751284 DOI: 10.1159/000127054  1
1995 Malagié I, Trillat AC, Jacquot C, Gardier AM. Effects of acute fluoxetine on extracellular serotonin levels in the raphe: an in vivo microdialysis study. European Journal of Pharmacology. 286: 213-7. PMID 8605960 DOI: 10.1016/0014-2999(95)00573-4  1
1995 Gardier AM, Jacquot C, Artigas F. Serotonin selective reuptake inhibitors | BASE NEUROBIOLOGIQUE DU ROLE DES RECEPTEURS 5-HT(1A) DANS LE MODE D'ACTION DES ANTIDEPRESSEURS SEROTONINERGIQUES Medecine/Sciences. 11: 1407-1417.  1
1994 Gardier AM, Lepoul E, Trouvin JH, Chanut E, Dessalles MC, Jacquot C. Changes in dopamine metabolism in rat forebrain regions after cessation of long-term fluoxetine treatment: relationship with brain concentrations of fluoxetine and norfluoxetine. Life Sciences. 54: PL51-6. PMID 8289580 DOI: 10.1016/0024-3205(94)00821-3  1
1994 Gardier AM, Trillat AC, Malagié I, Jacquot C. 8-OH-DPAT attenuates the dexfenfluramine-induced increase in extracellular serotonin: an in vivo dialysis study. European Journal of Pharmacology. 265: 107-10. PMID 7883022 DOI: 10.1016/0014-2999(94)90231-3  1
1994 Erfurth A, Gardier AM, Ribeiro E, Wurtman RJ. Effects of subchronic pretreatment with D-fenfluramine or p-chloroamphetamine on [3H]inositolmonophosphate accumulation in rat cortical miniprisms. Brain Research. 665: 107-14. PMID 7882002 DOI: 10.1016/0006-8993(94)91158-4  1
1994 Gardier AM, Kachaner S, Kahn Shaghaghi E, Blot C, Bohuon C, Jacquot C, Pallardy MJ. Effects of a primary immune response to T-cell dependent antigen on serotonin metabolism in frontal cortex: in vivo microdialysis study in freely moving Fischer 344 rat. Brain Research. 645: 150-6. PMID 7520341 DOI: 10.1016/0006-8993(94)91648-9  1
1993 Gardier AM, Mathé D, Guédeney X, Barré J, Benvenutti C, Navarro N, Vernillet L, Loisance D, Cachera JP, Jacotot B. Effects of plasma lipid levels on blood distribution and pharmacokinetics of cyclosporin A. Therapeutic Drug Monitoring. 15: 274-80. PMID 8236361  1
1993 Trouvin JH, Gardier AM, Chanut E, Pages N, Jacquot C. Time course of brain serotonin metabolism after cessation of long-term fluoxetine treatment in the rat. Life Sciences. 52: PL187-92. PMID 7683363 DOI: 10.1016/0024-3205(93)90116-K  1
1993 Chanut E, Trouvin JH, Bondoux D, Gardier A, Launay JM, Jacquot C. Metabolism of 6-fluoro-DL-tryptophan and its specific effects on the rat brain serotoninergic pathway. Biochemical Pharmacology. 45: 1049-57. PMID 7681671 DOI: 10.1016/0006-2952(93)90249-V  1
1992 Gardier AM, Kaakkola S, Erfurth A, Wurtman RJ. Effects of methiothepin on changes in brain serotonin release induced by repeated administration of high doses of anorectic serotoninergic drugs. Brain Research. 588: 67-74. PMID 1382807 DOI: 10.1016/0006-8993(92)91345-F  1
1991 Gardier AM, Wurtman RJ. Persistent blockade of potassium-evoked serotonin release from rat frontocortical terminals after fluoxetine administration. Brain Research. 540: 325-30. PMID 1711396 DOI: 10.1016/0006-8993(91)90530-9  1
1989 Gardier AM, Trouvin JH, Orosco M, Nicolaidis S, Jacquot C. Effects of food intake and body weight on a serotonergic turnover index in rat hypothalamus. Brain Research Bulletin. 22: 531-5. PMID 2713725 DOI: 10.1016/0361-9230(89)90106-8  1
1989 Bree F, Rouzeau JD, Durand G, Gardier A, Tillement JP. Comparison of drug binding capacities of three AAG glycan variants of human origin. Progress in Clinical and Biological Research. 300: 405-8. PMID 2506553  1
1988 Hamberger C, Barre J, Urien S, Gardier A, Tillement JP. Comparison of different methods for lysing whole blood to measure cyclosporin A by radioimmunoassay. Therapeutic Drug Monitoring. 10: 501. PMID 3201538  1
1987 Trouvin JH, Gardier A, El Gemayel G, Jacquot C. Rapid and specific determination of serotonin, its precursors and metabolites in rat brain tissue by liquid chromatography with electrochemical detection Journal of Liquid Chromatography. 10: 121-136. DOI: 10.1080/01483918708074196  1
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