Bertha Madras - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
Psychobiology
Website:
http://www.hms.harvard.edu/Academy/academy/members.html#m

144 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Madras BK. Vesicular monoamine transporter 2 loss in human cocaine abusers confirmed in nonhuman primate brain. Biological Psychiatry. 77: 421-2. PMID 25645272 DOI: 10.1016/j.biopsych.2014.12.015  1
2014 Madras BK. Dopamine challenge reveals neuroadaptive changes in marijuana abusers. Proceedings of the National Academy of Sciences of the United States of America. 111: 11915-6. PMID 25114244 DOI: 10.1073/pnas.1412314111  1
2014 Faraone SV, Spencer TJ, Madras BK, Zhang-James Y, Biederman J. Response to Selveraj et al. Molecular Psychiatry. 19: 964-5. PMID 24686137 DOI: 10.1038/mp.2014.26  1
2014 Faraone SV, Spencer TJ, Madras BK, Zhang-James Y, Biederman J. Functional effects of dopamine transporter gene genotypes on in vivo dopamine transporter functioning: a meta-analysis. Molecular Psychiatry. 19: 880-9. PMID 24061496 DOI: 10.1038/mp.2013.126  1
2013 Katz NP, Birnbaum H, Brennan MJ, Freedman JD, Gilmore GP, Jay D, Kenna GA, Madras BK, McElhaney L, Weiss RD, White AG. Prescription opioid abuse: challenges and opportunities for payers. The American Journal of Managed Care. 19: 295-302. PMID 23725361  1
2013 Madras BK. History of the discovery of the antipsychotic dopamine D2 receptor: a basis for the dopamine hypothesis of schizophrenia. Journal of the History of the Neurosciences. 22: 62-78. PMID 23323533 DOI: 10.1080/0964704X.2012.678199  1
2013 Spencer TJ, Biederman J, Faraone SV, Madras BK, Bonab AA, Dougherty DD, Batchelder H, Clarke A, Fischman AJ. Functional genomics of attention-deficit/hyperactivity disorder (ADHD) risk alleles on dopamine transporter binding in ADHD and healthy control subjects. Biological Psychiatry. 74: 84-9. PMID 23273726 DOI: 10.1016/j.biopsych.2012.11.010  1
2013 Miller GM, Madras BK, Xie Z. Trace Amine Associated Receptor 1 is a Catecholamine Receptor that Differentially Controls DAT and NET Internalization Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 48. DOI: 10.1016/B978-0-12-800044-1.00042-8  1
2013 Madras B. Drug Use and Its Consequences The Effects of Drug Abuse On the Human Nervous System. 1-35. DOI: 10.1016/B978-0-12-418679-8.00001-0  1
2013 Madras BK. Marijuana: A human experiment without informed consent Journal of Global Drug Policy and Practice. 7.  1
2013 Madras B, Kuhar M. The Effects of Drug Abuse on the Human Nervous System The Effects of Drug Abuse On the Human Nervous System. 1-609.  1
2012 Spencer TJ, Madras BK, Fischman AJ, Krause J, La Fougère C. Striatal dopamine transporter binding in adults with ADHD. The American Journal of Psychiatry. 169: 665; author reply 66. PMID 22684601 DOI: 10.1176/appi.ajp.2012.12020232  1
2012 Torun L, Madras BK, Meltzer PC. Synthesis and structure-activity relationship studies of 3-biaryl-8-oxabicyclo[3.2.1]octane-2-carboxylic acid methyl esters. Bioorganic & Medicinal Chemistry. 20: 2762-72. PMID 22398259 DOI: 10.1016/j.bmc.2012.01.053  1
2011 Westmoreland SV, Annamalai L, Lentz MR, Ratai EM, Assaf B, Boisvert K, Huynh T, Vallender EJ, Miller GM, Madras BK, Gonzalez RG. Growth-associated protein-43 and ephrin B3 induction in the brain of adult SIV-infected rhesus macaques. Journal of Neurovirology. 17: 455-68. PMID 21789725 DOI: 10.1007/s13365-011-0047-0  1
2011 Madras BK. Candidate performance measures for screening for, assessing, and treating unhealthy substance use in hospitals. Annals of Internal Medicine. 154: 72-3; author reply 7. PMID 21200046 DOI: 10.7326/0003-4819-154-1-201101040-00016  1
2011 Purushotham M, Sheri A, Pham-Huu DP, Madras BK, Janowsky A, Meltzer PC. The synthesis and biological evaluation of 2-(3-methyl or 3-phenylisoxazol-5-yl)-3-aryl-8-thiabicyclo[3.2.1]octanes. Bioorganic & Medicinal Chemistry Letters. 21: 48-51. PMID 21146984 DOI: 10.1016/j.bmcl.2010.11.076  1
2010 Spencer TJ, Madras BK, Bonab AA, Dougherty DD, Clarke A, Mirto T, Martin J, Fischman AJ. A positron emission tomography study examining the dopaminergic activity of armodafinil in adults using [¹¹C]altropane and [¹¹C]raclopride. Biological Psychiatry. 68: 964-70. PMID 21035624 DOI: 10.1016/j.biopsych.2010.08.026  1
2010 Madras BK. Office of National Drug Control Policy: a scientist in drug policy in Washington, DC. Annals of the New York Academy of Sciences. 1187: 370-402. PMID 20201863 DOI: 10.1111/j.1749-6632.2009.05278.x  1
2009 Madras BK, Compton WM, Avula D, Stegbauer T, Stein JB, Clark HW. Screening, brief interventions, referral to treatment (SBIRT) for illicit drug and alcohol use at multiple healthcare sites: comparison at intake and 6 months later. Drug and Alcohol Dependence. 99: 280-95. PMID 18929451 DOI: 10.1016/j.drugalcdep.2008.08.003  1
2008 Verrico CD, Lynch L, Fahey MA, Fryer AK, Miller GM, Madras BK. MDMA-induced impairment in primates: antagonism by a selective norepinephrine or serotonin, but not by a dopamine/norepinephrine transport inhibitor. Journal of Psychopharmacology (Oxford, England). 22: 187-202. PMID 18308800 DOI: 10.1177/0269881107083639  1
2007 Spencer TJ, Biederman J, Madras BK, Dougherty DD, Bonab AA, Livni E, Meltzer PC, Martin J, Rauch S, Fischman AJ. Further evidence of dopamine transporter dysregulation in ADHD: a controlled PET imaging study using altropane. Biological Psychiatry. 62: 1059-61. PMID 17511972 DOI: 10.1016/j.biopsych.2006.12.008  1
2007 Xie Z, Westmoreland SV, Bahn ME, Chen GL, Yang H, Vallender EJ, Yao WD, Madras BK, Miller GM. Rhesus monkey trace amine-associated receptor 1 signaling: enhancement by monoamine transporters and attenuation by the D2 autoreceptor in vitro. The Journal of Pharmacology and Experimental Therapeutics. 321: 116-27. PMID 17234900 DOI: 10.1124/jpet.106.116863  1
2007 Pham-Huu DP, Deschamps JR, Liu S, Madras BK, Meltzer PC. Synthesis of 8-thiabicyclo[3.2.1]octanes and their binding affinity for the dopamine and serotonin transporters. Bioorganic & Medicinal Chemistry. 15: 1067-82. PMID 17070057 DOI: 10.1016/j.bmc.2006.10.016  1
2007 Verrico CD, Miller GM, Madras BK. MDMA (Ecstasy) and human dopamine, norepinephrine, and serotonin transporters: implications for MDMA-induced neurotoxicity and treatment. Psychopharmacology. 189: 489-503. PMID 16220332 DOI: 10.1007/s00213-005-0174-5  1
2006 Madras BK, Fahey MA, Goulet M, Lin Z, Bendor J, Goodrich C, Meltzer PC, Elmaleh DR, Livni E, Bonab AA, Fischman AJ. Dopamine transporter (DAT) inhibitors alleviate specific parkinsonian deficits in monkeys: association with DAT occupancy in vivo. The Journal of Pharmacology and Experimental Therapeutics. 319: 570-85. PMID 16885433 DOI: 10.1124/jpet.106.105312  1
2006 Madras BK, Xie Z, Lin Z, Jassen A, Panas H, Lynch L, Johnson R, Livni E, Spencer TJ, Bonab AA, Miller GM, Fischman AJ. Modafinil occupies dopamine and norepinephrine transporters in vivo and modulates the transporters and trace amine activity in vitro. The Journal of Pharmacology and Experimental Therapeutics. 319: 561-9. PMID 16885432 DOI: 10.1124/jpet.106.106583  1
2006 Lin Z, Madras BK. Human genetics and pharmacology of neurotransmitter transporters. Handbook of Experimental Pharmacology. 327-71. PMID 16722243 DOI: 10.1007/3-540-29784-7-16  1
2006 Jassen AK, Yang H, Miller GM, Calder E, Madras BK. Receptor regulation of gene expression of axon guidance molecules: implications for adaptation. Molecular Pharmacology. 70: 71-7. PMID 16595738 DOI: 10.1124/mol.105.021998  1
2006 Spencer TJ, Biederman J, Ciccone PE, Madras BK, Dougherty DD, Bonab AA, Livni E, Parasrampuria DA, Fischman AJ. PET study examining pharmacokinetics, detection and likeability, and dopamine transporter receptor occupancy of short- and long-acting oral methylphenidate. The American Journal of Psychiatry. 163: 387-95. PMID 16513858 DOI: 10.1176/appi.ajp.163.3.387  1
2006 Meltzer PC, Butler D, Deschamps JR, Madras BK. 1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors. Journal of Medicinal Chemistry. 49: 1420-32. PMID 16480278 DOI: 10.1021/jm050797a  1
2006 Xiao D, Miller GM, Jassen A, Westmoreland SV, Pauley D, Madras BK. Ephrin/Eph receptor expression in brain of adult nonhuman primates: implications for neuroadaptation. Brain Research. 1067: 67-77. PMID 16360648 DOI: 10.1016/j.brainres.2005.10.073  1
2006 Anderson CM, Maas LC, Frederick Bd, Bendor JT, Spencer TJ, Livni E, Lukas SE, Fischman AJ, Madras BK, Renshaw PF, Kaufman MJ. Cerebellar vermis involvement in cocaine-related behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1318-26. PMID 16237382 DOI: 10.1038/sj.npp.1300937  1
2006 Torun L, Liu S, Madras BK, Meltzer PC. Synthesis of 3-(4-heteroaryl-phenyl)-8-oxabicyclo[3.2.1]octane-2-carboxylic acid methyl esters Tetrahedron Letters. 47: 599-603. DOI: 10.1016/j.tetlet.2005.10.170  1
2005 Jassen AK, Brown JM, Panas HN, Miller GM, Xiao D, Madras BK. Variants of the primate vesicular monoamine transporter-2. Brain Research. Molecular Brain Research. 139: 251-7. PMID 15978697 DOI: 10.1016/j.molbrainres.2005.05.028  1
2005 Madras BK, Miller GM, Fischman AJ. The dopamine transporter and attention-deficit/hyperactivity disorder. Biological Psychiatry. 57: 1397-409. PMID 15950014 DOI: 10.1016/j.biopsych.2004.10.011  1
2005 Fischman AJ, Madras BK. The neurobiology of attention-deficit/hyperactivity disorder. Biological Psychiatry. 57: 1374-6. PMID 15950010 DOI: 10.1016/j.biopsych.2005.03.035  1
2005 Spencer TJ, Biederman J, Madras BK, Faraone SV, Dougherty DD, Bonab AA, Fischman AJ. In vivo neuroreceptor imaging in attention-deficit/hyperactivity disorder: a focus on the dopamine transporter. Biological Psychiatry. 57: 1293-300. PMID 15950001 DOI: 10.1016/j.biopsych.2005.03.036  1
2005 Miller GM, Verrico CD, Jassen A, Konar M, Yang H, Panas H, Bahn M, Johnson R, Madras BK. Primate trace amine receptor 1 modulation by the dopamine transporter. The Journal of Pharmacology and Experimental Therapeutics. 313: 983-94. PMID 15764732 DOI: 10.1124/jpet.105.084459  1
2005 Yatin SM, Miller GM, Madras BK. Dopamine and norepinephrine transporter-dependent c-Fos production in vitro: relevance to neuroadaptation. Journal of Neuroscience Methods. 143: 69-78. PMID 15763138 DOI: 10.1016/j.jneumeth.2004.09.016  1
2005 Miller GM, Madras BK. Similarities of Non-Human Primates to Humans. Genetic Variations and Phenotypic Associations Common to Rhesus Monkeys and Humans The Laboratory Primate. 17-27. DOI: 10.1016/B978-012080261-6/50002-7  1
2004 Meltzer PC, Pham-Huu DP, Madras BK. Synthesis of 8-thiabicyclo[3.2.1]oct-2-enes and their binding affinity for the dopamine and serotonin transporters. Bioorganic & Medicinal Chemistry Letters. 14: 6007-10. PMID 15546718 DOI: 10.1016/j.bmcl.2004.09.080  1
2004 Saka E, Goodrich C, Harlan P, Madras BK, Graybiel AM. Repetitive behaviors in monkeys are linked to specific striatal activation patterns. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7557-65. PMID 15329403 DOI: 10.1523/JNEUROSCI.1072-04.2004  1
2004 Miller GM, Bendor J, Tiefenbacher S, Yang H, Novak MA, Madras BK. A mu-opioid receptor single nucleotide polymorphism in rhesus monkey: association with stress response and aggression. Molecular Psychiatry. 9: 99-108. PMID 14699447 DOI: 10.1038/sj.mp.4001378  1
2003 Madras BK, Fahey MA, Miller GM, De La Garza R, Goulet M, Spealman RD, Meltzer PC, George SR, O'Dowd BF, Bonab AA, Livni E, Fischman AJ. Non-amine-based dopamine transporter (reuptake) inhibitors retain properties of amine-based progenitors. European Journal of Pharmacology. 479: 41-51. PMID 14612136 DOI: 10.1016/j.ejphar.2003.08.055  1
2003 Meltzer PC, McPhee M, Madras BK. Synthesis and biological activity of 2-carbomethoxy-3-catechol-8-azabicyclo[3.2.1]octanes. Bioorganic & Medicinal Chemistry Letters. 13: 4133-7. PMID 14592523 DOI: 10.1016/j.bmcl.2003.07.014  1
2003 Meltzer PC, Blundell P, Zona T, Yang L, Huang H, Bonab AA, Livni E, Fischman A, Madras BK. A second-generation 99m technetium single photon emission computed tomography agent that provides in vivo images of the dopamine transporter in primate brain. Journal of Medicinal Chemistry. 46: 3483-96. PMID 12877586 DOI: 10.1021/jm0301484  1
2003 Meltzer PC, Wang P, Blundell P, Madras BK. Synthesis and evaluation of dopamine and serotonin transporter inhibition by oxacyclic and carbacyclic analogues of methylphenidate. Journal of Medicinal Chemistry. 46: 1538-45. PMID 12672255 DOI: 10.1021/jm0205292  1
2002 Meltzer PC, Liu S, Blanchette H, Blundell P, Madras BK. Design and synthesis of an irreversible dopamine-sparing cocaine antagonist. Bioorganic & Medicinal Chemistry. 10: 3583-91. PMID 12213473 DOI: 10.1016/S0968-0896(02)00244-4  1
2002 Yatin SM, Miller GM, Norton C, Madras BK. Dopamine transporter-dependent induction of C-Fos in HEK cells. Synapse (New York, N.Y.). 45: 52-65. PMID 12112414 DOI: 10.1002/syn.10084  1
2002 Zhdanova IV, Geiger DA, Schwagerl AL, Leclair OU, Killiany R, Taylor JA, Rosene DL, Moss MB, Madras BK. Melatonin promotes sleep in three species of diurnal nonhuman primates. Physiology & Behavior. 75: 523-9. PMID 12062316 DOI: 10.1016/S0031-9384(02)00654-6  1
2002 Seeman P, Madras B. Methylphenidate elevates resting dopamine which lowers the impulse-triggered release of dopamine: a hypothesis. Behavioural Brain Research. 130: 79-83. PMID 11864721 DOI: 10.1016/S0166-4328(01)00435-1  1
2002 Madras BK, Miller GM, Fischman AJ. The dopamine transporter: relevance to attention deficit hyperactivity disorder (ADHD). Behavioural Brain Research. 130: 57-63. PMID 11864718 DOI: 10.1016/S0166-4328(01)00439-9  1
2002 Miller GM, Madras BK. Polymorphisms in the 3'-untranslated region of human and monkey dopamine transporter genes affect reporter gene expression. Molecular Psychiatry. 7: 44-55. PMID 11803445 DOI: 10.1038/sj/mp/4000921  1
2001 Goulet M, Miller GM, Bendor J, Liu S, Meltzer PC, Madras BK. Non-amines, drugs without an amine nitrogen, potently block serotonin transport: novel antidepressant candidates? Synapse (New York, N.Y.). 42: 129-40. PMID 11746710 DOI: 10.1002/syn.1108  1
2001 Meltzer PC, Wang B, Chen Z, Blundell P, Jayaraman M, Gonzalez MD, George C, Madras BK. Synthesis of 6- and 7- hydroxy-8-azabicyclo[3.2.1]octanes and their binding affinity for the dopamine and serotonin transporters. Journal of Medicinal Chemistry. 44: 2619-35. PMID 11472216 DOI: 10.1021/jm0101242  1
2001 Meschler JP, Howlett AC, Madras BK. Cannabinoid receptor agonist and antagonist effects on motor function in normal and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-treated non-human primates. Psychopharmacology. 156: 79-85. PMID 11465637 DOI: 10.1007/s002130100728  1
2001 Miller GM, De La Garza R, Novak MA, Madras BK. Single nucleotide polymorphisms distinguish multiple dopamine transporter alleles in primates: implications for association with attention deficit hyperactivity disorder and other neuropsychiatric disorders. Molecular Psychiatry. 6: 50-8. PMID 11244485 DOI: 10.1038/sj.mp.4000809  1
2001 Miller GM, Yatin SM, De La Garza R, Goulet M, Madras BK. Cloning of dopamine, norepinephrine and serotonin transporters from monkey brain: relevance to cocaine sensitivity. Brain Research. Molecular Brain Research. 87: 124-43. PMID 11223167 DOI: 10.1016/S0169-328X(00)00288-6  1
2001 Dutta AK, Reith ME, Madras BK. Synthesis and preliminary characterization of a high-affinity novel radioligand for the dopamine transporter. Synapse (New York, N.Y.). 39: 175-81. PMID 11180505 DOI: 10.1002/1098-2396(200102)39:2<175::AID-SYN9>3.0.CO;2-W  1
2001 Fischman AJ, Bonab AA, Babich JW, Livni E, Alpert NM, Meltzer PC, Madras BK. [(11)C, (127)I] Altropane: a highly selective ligand for PET imaging of dopamine transporter sites. Synapse (New York, N.Y.). 39: 332-42. PMID 11169784 DOI: 10.1002/1098-2396(20010315)39:4<332::AID-SYN1017>3.0.CO;2-X  1
2000 Madras BK, Miller GM, Meltzer PC, Brownell AL, Fischman AJ. Molecular and regional targets of cocaine in primate brain: liberation from prosaic views. Addiction Biology. 5: 351-9. PMID 20575852 DOI: 10.1111/j.1369-1600.2000.tb00202.x  1
2000 Meltzer PC, Blundell P, Yong YF, Chen Z, George C, Gonzalez MD, Madras BK. 2-Carbomethoxy-3-aryl-8-bicyclo[3.2.1]octanes: potent non-nitrogen inhibitors of monoamine transporters. Journal of Medicinal Chemistry. 43: 2982-91. PMID 10956207 DOI: 10.1021/jm000191g  1
2000 De La Garza R, Madras BK. [(3)H]PNU-101958, a D(4) dopamine receptor probe, accumulates in prefrontal cortex and hippocampus of non-human primate brain. Synapse (New York, N.Y.). 37: 232-44. PMID 10881045 DOI: 10.1002/1098-2396(20000901)37:3<232::AID-SYN7>3.0.CO;2-7  1
2000 Baughman F.A. J, Swanson JM, Dougherty DD, Bonab AA, Spencer TJ, Madras BK, Fischman AJ. Dopamine-transporter density in patients with ADHD (multiple letters) Lancet. 355: 1460-1462. PMID 10791547  1
2000 Meltzer PC, Blundell P, Huang H, Liu S, Yong YF, Madras BK. 3-Aryl-2-carbomethoxybicyclo[3.2.1]oct-2-enes inhibit WIN 35,428 binding potently and selectively at the dopamine transporter. Bioorganic & Medicinal Chemistry. 8: 581-90. PMID 10732975 DOI: 10.1016/S0968-0896(99)00322-3  1
2000 Meschler JP, Clarkson FA, Mathews PJ, Howlett AC, Madras BK. D(2), but not D(1) dopamine receptor agonists potentiate cannabinoid-induced sedation in nonhuman primates. The Journal of Pharmacology and Experimental Therapeutics. 292: 952-9. PMID 10688609  1
2000 Goulet M, Madras BK. D(1) dopamine receptor agonists are more effective in alleviating advanced than mild parkinsonism in 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated monkeys. The Journal of Pharmacology and Experimental Therapeutics. 292: 714-24. PMID 10640310  1
1999 Dougherty DD, Bonab AA, Spencer TJ, Rauch SL, Madras BK, Fischman AJ. Dopamine transporter density in patients with attention deficit hyperactivity disorder. Lancet. 354: 2132-3. PMID 10609822 DOI: 10.1016/S0140-6736(99)04030-1  1
1999 De La Garza R, Meltzer PC, Madras BK. Non-amine dopamine transporter probe [(3)H]tropoxene distributes to dopamine-rich regions of monkey brain. Synapse (New York, N.Y.). 34: 20-7. PMID 10459168 DOI: 10.1002/(SICI)1098-2396(199910)34:1<20::AID-SYN3>3.0.CO;2-4  1
1999 Morris ED, Bonab AA, Alpert NM, Fischman AJ, Madras BK, Christian BT. Concentration of dopamine transporters: to Bmax or not to Bmax? Synapse (New York, N.Y.). 32: 136-40. PMID 10231133 DOI: 10.1002/(SICI)1098-2396(199905)32:2<136::AID-SYN7>3.0.CO;2-G  1
1999 Meltzer PC, Blundell P, Chen Z, Yong YF, Madras BK. Bicyclo[3.2.1]octanes: synthesis and inhibition of binding at the dopamine and serotonin transporters. Bioorganic & Medicinal Chemistry Letters. 9: 857-62. PMID 10206550 DOI: 10.1016/S0960-894X(99)00098-0  1
1998 Seeman P, Madras BK. Anti-hyperactivity medication: methylphenidate and amphetamine. Molecular Psychiatry. 3: 386-96. PMID 9774771  1
1998 Fischman AJ, Bonab AA, Babich JW, Palmer EP, Alpert NM, Elmaleh DR, Callahan RJ, Barrow SA, Graham W, Meltzer PC, Hanson RN, Madras BK. Rapid detection of Parkinson's disease by SPECT with altropane: a selective ligand for dopamine transporters. Synapse (New York, N.Y.). 29: 128-41. PMID 9593103 DOI: 10.1002/(SICI)1098-2396(199806)29:2<128::AID-SYN4>3.0.CO;2-9  1
1998 Madras BK, Gracz LM, Fahey MA, Elmaleh D, Meltzer PC, Liang AY, Stopa EG, Babich J, Fischman AJ. Altropane, a SPECT or PET imaging probe for dopamine neurons: III. Human dopamine transporter in postmortem normal and Parkinson's diseased brain. Synapse (New York, N.Y.). 29: 116-27. PMID 9593102 DOI: 10.1002/(SICI)1098-2396(199806)29:2<116::AID-SYN3>3.0.CO;2-A  1
1998 Madras BK, Gracz LM, Meltzer PC, Liang AY, Elmaleh DR, Kaufman MJ, Fischman AJ. Altropane, a SPECT or PET imaging probe for dopamine neurons: II. Distribution to dopamine-rich regions of primate brain. Synapse (New York, N.Y.). 29: 105-15. PMID 9593101 DOI: 10.1002/(SICI)1098-2396(199806)29:2<105::AID-SYN2>3.0.CO;2-B  1
1998 Madras BK, Meltzer PC, Liang AY, Elmaleh DR, Babich J, Fischman AJ. Altropane, a SPECT or PET imaging probe for dopamine neurons: I. Dopamine transporter binding in primate brain. Synapse (New York, N.Y.). 29: 93-104. PMID 9593100 DOI: 10.1002/(SICI)1098-2396(199806)29:2<93::AID-SYN1>3.0.CO;2-5  1
1998 Meltzer PC, Blundell P, Madras BK. Structure activity relationships of inhibition of the dopamine transporter by 3-arylbicyclo[3.2.1]octanes Medicinal Chemistry Research. 8: 12-34.  1
1997 Meltzer PC, Liang AY, Blundell P, Gonzalez MD, Chen Z, George C, Madras BK. 2-Carbomethoxy-3-aryl-8-oxabicyclo[3.2.1]octanes: potent non-nitrogen inhibitors of monoamine transporters. Journal of Medicinal Chemistry. 40: 2661-73. PMID 9276012 DOI: 10.1021/jm9703045  1
1997 Meltzer PC, Madras BK. Imaging of dopamine transporters in humans with technetium-99m TRODAT-1. European Journal of Nuclear Medicine. 24: 462-3. PMID 9198580  1
1997 Meltzer PC, Blundell P, Jones AG, Mahmood A, Garada B, Zimmerman RE, Davison A, Holman BL, Madras BK. A technetium-99m SPECT imaging agent which targets the dopamine transporter in primate brain. Journal of Medicinal Chemistry. 40: 1835-44. PMID 9191960 DOI: 10.1021/jm960868t  1
1997 Fischman AJ, Babich JW, Elmaleh DR, Barrow SA, Meltzer P, Hanson RN, Madras BK. SPECT imaging of dopamine transporter sites in normal and MPTP-Treated rhesus monkeys. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 38: 144-50. PMID 8998169  1
1996 Madras BK, Pristupa ZB, Niznik HB, Liang AY, Blundell P, Gonzalez MD, Meltzer PC. Nitrogen-based drugs are not essential for blockade of monoamine transporters. Synapse (New York, N.Y.). 24: 340-8. PMID 10638825 DOI: 10.1002/(SICI)1098-2396(199612)24:4<340::AID-SYN4>3.0.CO;2-D  1
1996 Madras BK, Jones AG, Mahmood A, Zimmerman RE, Garada B, Holman BL, Davison A, Blundell P, Meltzer PC. Technepine: a high-affinity 99m-technetium probe to label the dopamine transporter in brain by SPECT imaging. Synapse (New York, N.Y.). 22: 239-46. PMID 9132992 DOI: 10.1002/(SICI)1098-2396(199603)22:3<239::AID-SYN6>3.0.CO;2-D  1
1996 Elmaleh DR, Fischman AJ, Shoup TM, Byon C, Hanson RN, Liang AY, Meltzer PC, Madras BK. Preparation and biological evaluation of iodine-125-IACFT: a selective SPECT agent for imaging dopamine transporter sites. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 37: 1197-202. PMID 8965198  1
1996 Brownell AL, Elmaleh DR, Meltzer PC, Shoup TM, Brownell GL, Fischman AJ, Madras BK. Cocaine congeners as PET imaging probes for dopamine terminals. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 37: 1186-92. PMID 8965196  1
1996 Morris ED, Babich JW, Alpert NM, Bonab AA, Livni E, Weise S, Hsu H, Christian BT, Madras BK, Fischman AJ. Quantification of dopamine transporter density in monkeys by dynamic PET imaging of multiple injections of 11C-CFT. Synapse (New York, N.Y.). 24: 262-72. PMID 8923667 DOI: 10.1002/(SICI)1098-2396(199611)24:3<262::AID-SYN9>3.0.CO;2-C  1
1996 Bergman J, Spealman RD, Madras BK, Rosenzweig-Lipson S. Agonist efficacy and the behavioral effects of dopamine D1 receptor ligands: drug interaction studies in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 276: 942-50. PMID 8786574  1
1996 Meltzer PC, Liang AY, Madras BK. 2-Carbomethoxy-3-(diarylmethoxy)-1 alpha H, 5 alpha H-tropane analogs: synthesis and inhibition of binding at the dopamine transporter and comparison with piperazines of the GBR series. Journal of Medicinal Chemistry. 39: 371-9. PMID 8558504 DOI: 10.1021/jm950463t  1
1995 Gracz LM, Madras BK. [3H]WIN 35,428 ([3H]CFT) binds to multiple charge-states of the solubilized dopamine transporter in primate striatum. The Journal of Pharmacology and Experimental Therapeutics. 273: 1224-34. PMID 7791095  1
1994 Madras BK. 11C-WIN 35,428 for detecting dopamine depletion in mild Parkinson's disease. Annals of Neurology. 35: 376-7. PMID 8122895 DOI: 10.1002/ana.410350326  1
1994 Madras BK, Reith ME, Meltzer PC, Dutta AK. O-526, a piperidine analog of GBR 12909, retains high affinity for the dopamine transporter in monkey caudate-putamen. European Journal of Pharmacology. 267: 167-73. PMID 8050478 DOI: 10.1016/0922-4106(94)90168-6  1
1994 Meltzer PC, Liang AY, Madras BK. The discovery of an unusually selective and novel cocaine analog: difluoropine. Synthesis and inhibition of binding at cocaine recognition sites. Journal of Medicinal Chemistry. 37: 2001-10. PMID 8027983  1
1994 Brownell AL, Hantraye P, Wullner U, Hamberg L, Shoup T, Elmaleh DR, Frim DM, Madras BK, Brownell GL, Rosen BR. PET- and MRI-based assessment of glucose utilization, dopamine receptor binding, and hemodynamic changes after lesions to the caudate-putamen in primates. Experimental Neurology. 125: 41-51. PMID 7905836 DOI: 10.1006/exnr.1994.1004  1
1994 Madras BK, Kaufman MJ. Cocaine accumulates in dopamine-rich regions of primate brain after i.v. administration: comparison with mazindol distribution. Synapse (New York, N.Y.). 18: 261-75. PMID 7855738 DOI: 10.1002/syn.890180311  1
1994 Madras BK, Elmaleh DR, Meltzer PC, Liang AY, Brownell GL, Brownell AL. Positron emission tomography of cocaine binding sites on the dopamine transporter. Nida Research Monograph. 138: 57-69. PMID 7603545  1
1994 Elmaleh DR, Byon C, Fischman AJ, Hanson RN, Meltzer P, Madras BK. Radiosynthesis and evaluation of E and Z N-iodoallyl-2b-carbomethoxy-3b- (4-fluorophenyl (I) tropane (IACFT) Journal of Labelled Compounds and Radiopharmaceuticals. 35: 491-493.  1
1993 Meltzer PC, Liang AY, Brownell AL, Elmaleh DR, Madras BK. Substituted 3-phenyltropane analogs of cocaine: synthesis, inhibition of binding at cocaine recognition sites, and positron emission tomography imaging. Journal of Medicinal Chemistry. 36: 855-62. PMID 8464040  1
1993 Kaufman MJ, Madras BK. [3H]CFT ([3H]WIN 35,428) accumulation in dopamine regions of monkey brain: comparison of a mature and an aged monkey. Brain Research. 611: 322-5. PMID 8334525 DOI: 10.1016/0006-8993(93)90519-S  1
1993 Madras BK, Kaufman MJ. In vivo distribution of [3H](-)-cocaine in primate brain: Comparison with [3H]mazindol distribution Nida Research Monograph Series. 107.  1
1992 Hantraye P, Brownell AL, Elmaleh D, Spealman RD, Wüllner U, Brownell GL, Madras BK, Isacson O. Dopamine fiber detection by [11C]-CFT and PET in a primate model of parkinsonism. Neuroreport. 3: 265-8. PMID 1515582  1
1992 Kaufman MJ, Madras BK. Distribution of cocaine recognition sites in monkey brain: II. Ex vivo autoradiography with [3H]CFT and [125I]RTI-55. Synapse (New York, N.Y.). 12: 99-111. PMID 1481136 DOI: 10.1002/syn.890120203  1
1992 Rosenzweig-Lipson S, Bergman J, Spealman RD, Madras BK. Stereoselective behavioral effects of Lu 19-005 in monkeys: relation to binding at cocaine recognition sites. Psychopharmacology. 107: 186-94. PMID 1377395 DOI: 10.1007/BF02245136  1
1992 Neumeyer JL, Baindur N, Bakthavachalam V, Yuan J, Madras BK, Kula NS, Campbell A, Baldessarini RJ. Alan Horn Memorial Lecture. Selective probes for characterization of dopamine D1 and D2 receptors. Neurochemistry International. 20: 63S-68S. PMID 1365458 DOI: 10.1016/0197-0186(92)90212-A  1
1992 Spealman RD, Bergman J, Madras BK, Kamien JB, Melia KF. Role of D1 and D2 dopamine receptors in the behavioral effects of cocaine. Neurochemistry International. 20: 147S-152S. PMID 1365414 DOI: 10.1016/0197-0186(92)90228-J  1
1992 Schumacher JM, Hantraye P, Brownell AL, Riche D, Madras BK, Davenport PD, Maziere M, Elmaleh DR, Brownell GL, Isacson O. A primate model of Huntington's disease: functional neural transplantation and CT-guided stereotactic procedures. Cell Transplantation. 1: 313-22. PMID 1344304  1
1991 Milius RA, Saha JK, Madras BK, Neumeyer JL. Synthesis and receptor binding of N-substituted tropane derivatives. High-affinity ligands for the cocaine receptor. Journal of Medicinal Chemistry. 34: 1728-31. PMID 2033595  1
1991 Bakthavachalam V, Baindur N, Madras BK, Neumeyer JL. Fluorescent probes for dopamine receptors: synthesis and characterization of fluorescein and 7-nitrobenz-2-oxa-1,3-diazol-4-yl conjugates of D-1 and D-2 receptor ligands. Journal of Medicinal Chemistry. 34: 3235-41. PMID 1956042  1
1991 Bergman J, Madras BK, Spealman RD. Behavioral effects of D1 and D2 dopamine receptor antagonists in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 258: 910-7. PMID 1890625  1
1991 Kaufman MJ, Madras BK. Severe depletion of cocaine recognition sites associated with the dopamine transporter in Parkinson's-diseased striatum. Synapse (New York, N.Y.). 9: 43-9. PMID 1796351 DOI: 10.1002/syn.890090107  1
1991 Kaufman MJ, Spealman RD, Madras BK. Distribution of cocaine recognition sites in monkey brain: I. In vitro autoradiography with [3H]CFT. Synapse (New York, N.Y.). 9: 177-87. PMID 1776130 DOI: 10.1002/syn.890090304  1
1991 Spealman RD, Bergman J, Madras BK. Self-administration of the high-affinity cocaine analog 2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane. Pharmacology, Biochemistry, and Behavior. 39: 1011-3. PMID 1763097 DOI: 10.1016/0091-3057(91)90067-C  1
1991 Spealman RD, Bergman J, Madras BK, Melia KF. Discriminative stimulus effects of cocaine in squirrel monkeys: involvement of dopamine receptor subtypes. The Journal of Pharmacology and Experimental Therapeutics. 258: 945-53. PMID 1679852  1
1990 Madras BK, Kamien JB, Fahey MA, Canfield DR, Milius RA, Saha JK, Neumeyer JL, Spealman RD. N-modified fluorophenyltropane analogs of cocaine with high affinity for cocaine receptors. Pharmacology, Biochemistry, and Behavior. 35: 949-53. PMID 2345768 DOI: 10.1016/0091-3057(90)90384-T  1
1990 Canfield DR, Spealman RD, Kaufman MJ, Madras BK. Autoradiographic localization of cocaine binding sites by [3H]CFT ([3H]WIN 35,428) in the monkey brain. Synapse (New York, N.Y.). 6: 189-95. PMID 2237780 DOI: 10.1002/syn.890060211  1
1990 Madras BK, Canfield DR, Pfaelzer C, Vittimberga FJ, Difiglia M, Aronin N, Bakthavachalam V, Baindur N, Neumeyer JL. Fluorescent and biotin probes for dopamine receptors: D1 and D2 receptor affinity and selectivity. Molecular Pharmacology. 37: 833-9. PMID 2141665  1
1989 Madras BK, Spealman RD, Fahey MA, Neumeyer JL, Saha JK, Milius RA. Cocaine receptors labeled by [3H]2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane. Molecular Pharmacology. 36: 518-24. PMID 2811854  1
1989 Spealman RD, Madras BK, Bergman J. Effects of cocaine and related drugs in nonhuman primates. II. Stimulant effects on schedule-controlled behavior. The Journal of Pharmacology and Experimental Therapeutics. 251: 142-9. PMID 2795456  1
1989 Bergman J, Madras BK, Johnson SE, Spealman RD. Effects of cocaine and related drugs in nonhuman primates. III. Self-administration by squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 251: 150-5. PMID 2529365  1
1989 Madras BK, Fahey MA, Bergman J, Canfield DR, Spealman RD. Effects of cocaine and related drugs in nonhuman primates. I. [3H]cocaine binding sites in caudate-putamen. The Journal of Pharmacology and Experimental Therapeutics. 251: 131-41. PMID 2529364  1
1988 Madras BK, Fahey MA, Canfield DR, Spealman RD. D1 and D2 dopamine receptors in caudate-putamen of nonhuman primates (Macaca fascicularis). Journal of Neurochemistry. 51: 934-43. PMID 2970527  1
1985 Madras BK, Seeman P. Drug potencies on partially purified brain D2 dopamine receptors. Journal of Neurochemistry. 44: 856-61. PMID 2579201  1
1983 Chan B, Madras BK. Partial purification of [3H]mianserin binding sites. European Journal of Pharmacology. 87: 357-65. PMID 6852094 DOI: 10.1016/0014-2999(83)90074-2  1
1983 Whitaker PM, Kish SJ, Madras BK. Direct binding assays in determining psychotropic drug mechanism of action. Reviews in Pure & Applied Pharmacological Sciences. 4: 271-338. PMID 6400556  1
1983 Okazaki MM, Madras BK, Livingston KE, Spero L, Burnham WM. Enhancement of 3H-phenytoin binding by diazepam and (+)bicuculline. Life Sciences. 33: 409-14. PMID 6308373 DOI: 10.1016/0024-3205(83)90788-9  1
1983 Madras BK, Chan B. Modulation of dopamine receptor binding by ascorbic acid. Advances in Biochemical Psychopharmacology. 37: 275-87. PMID 6138950  1
1982 Chan B, Madras BK. [3H]Mianserin binding to solubilized membranes of frontal cortex. European Journal of Pharmacology. 83: 1-10. PMID 7128693 DOI: 10.1016/0014-2999(82)90279-5  1
1982 Davis A, Madras BK, Seeman P. Solubilized receptors for [3H]dopamine (D3 binding sites) from canine brain. Biochemical Pharmacology. 31: 1183-7. PMID 7092913 DOI: 10.1016/0006-2952(82)90002-8  1
1982 Madras BK, Davis A, Seeman P. Comparison of soluble dopamine D2-receptors from three species. European Journal of Pharmacology. 78: 431-8. PMID 7075677 DOI: 10.1016/0014-2999(82)90485-X  1
1981 Chan B, Madras BK, Davis A, Seeman P. Assay for soluble dopamine receptors by the precipitation method. European Journal of Pharmacology. 74: 53-9. PMID 7318894 DOI: 10.1016/0014-2999(81)90322-8  1
1981 Burnham WM, Spero L, Okazaki MM, Madras BK. Saturable binding of [3H]phenytoin to rat brain membrane fraction. Canadian Journal of Physiology and Pharmacology. 59: 402-7. PMID 7016275  1
1981 Madras BK, Davis A, Chan B, Seeman P. Solubilized dopamine/neuroleptic receptors (D2-type). Progress in Neuro-Psychopharmacology. 5: 543-8. PMID 6122229 DOI: 10.1016/0364-7722(81)90043-6  1
1981 Davis A, Madras B, Seeman P. Solubilization of neuroleptic/dopamine receptors of human brain striatum. European Journal of Pharmacology. 70: 321-9. PMID 6112153 DOI: 10.1016/0014-2999(81)90166-7  1
1981 Davis A, Madras BK, Lilly L, Seeman P. Solubilized 3H-dopamine receptors (D3) receptors (D3)) of dog striatum Federation Proceedings. 40: 322.  1
1975 Fernstrom JD, Hirsch MJ, Madras BK, Sudarsky L. Effects of skim milk, whole milk and light cream on serum tryptophan binding and brain tryptophan concentrations in rats. The Journal of Nutrition. 105: 1359-62. PMID 1159526  1
1974 Madras BK, Cohen EL, Munro HN, Wurtman RJ. Elevation of serum free tryptophan, but not brain tryptophan, by serum nonesterified fatty acids. Advances in Biochemical Psychopharmacology. 11: 143-51. PMID 4845697  1
1974 Madras BK, Cohen EL, Messing R, Munro HN, Wurtman RJ. Relevance of free tryptophan in serum to tissue tryptophan concentrations. Metabolism: Clinical and Experimental. 23: 1107-16. PMID 4427559 DOI: 10.1016/0026-0495(74)90027-4  1
1974 Howd RA, Madras BK, Wurtman RJ. Tryptophan transport into brain slices Pharmacologist. 16: 339.  1
1973 Lipsett D, Madras BK, Wurtman RJ, Munro HN. Serum tryptophan level after carbohydrate ingestion: selective decline in non-albumin-bound tryptophan coincident with reduction in serum free fatty acids. Life Sciences. Pt. 2: Biochemistry, General and Molecular Biology. 12: 57-64. PMID 4707783 DOI: 10.1016/0024-3205(73)90027-1  1
1973 Madras BK, Cohen EL, Fernstrom JD, Larin F, Munro HN, Wurtman RJ. Letter: Dietary carbohydrate increases brain tryptophan and decreases free plasma tryptophan. Nature. 244: 34-5. PMID 4582482 DOI: 10.1038/244034a0  1
1973 Madras BK, Cohen EL, Fernstrom JD. Effects of carbohydrate (CHO) and insulin on serum free and albumin bound tryptophan (Trp) Federation Proceedings. 32: I.  1
1969 Sourkes TL, Missala K, Madras BK. Effect of yohimbine on tryptophan metabolism. The Journal of Pharmacology and Experimental Therapeutics. 165: 289-93. PMID 5763063  1
1968 Madras BK, Sourkes TL. Formation of respiratory 14CO2 from variously labeled forms of tryptophan-14C in intact and adrenalectomized rats. Archives of Biochemistry and Biophysics. 125: 829-36. PMID 5671046  1
1968 Madras BK, Sourkes TL. Effects of drugs on the metabolism of tryptophan. Alpha-hydrazinotryptophan and other amino acid analogs. Biochemical Pharmacology. 17: 1037-47. PMID 5301832  1
1965 Madras BK, Sourkes TL. Metabolism of alpha-methyltryptophan. Biochemical Pharmacology. 14: 1499-506. PMID 5867505  1
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