Ken Minneman - Related publications

Emory University, Atlanta, GA 
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Elisi GM, Bedini A, Scalvini L, Carmi C, Bartolucci S, Lucini V, Scaglione F, Mor M, Rivara S, Spadoni G. Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria. Molecules (Basel, Switzerland). 25. PMID 32899888 DOI: 10.3390/molecules25184057   
2020 Nasrollahi-Shirazi S, Szöllösi D, Yang Q, Muratspahic E, El-Kasaby A, Sucic S, Stockner T, Nanoff C, Freissmuth M. Functional Impact of the G279S Substitution in the Adenosine A-Receptor (AR-G279S), a Mutation Associated with Parkinson's Disease. Molecular Pharmacology. 98: 250-266. PMID 32817461 DOI: 10.1124/mol.120.000003   
2020 Schlezinger JJ, Heiger-Bernays W, Webster TF. Predicting the activation of the androgen receptor by mixtures of ligands using Generalized Concentration Addition. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32726424 DOI: 10.1093/toxsci/kfaa108   
2020 Srinivasalu N, Zhang S, Xu R, Reinach PS, Su Y, Zhu Y, Qu J, Zhou X. Crosstalk between EP2 and PPARα Modulates Hypoxic Signaling and Myopia Development in Guinea Pigs. Investigative Ophthalmology & Visual Science. 61: 44. PMID 32725213 DOI: 10.1167/iovs.61.8.44   
2020 Fan S, Zhao H, Liu Y, Zhang P, Wang Y, Xu Y, Gu K, Zhang T, Yu J, Qi W, Li Y, Zhang Y. Isoproterenol triggers ROS/P53/S100-A9 positive feedback to aggravate myocardial damage associated with complement activation. Chemical Research in Toxicology. PMID 32924446 DOI: 10.1021/acs.chemrestox.0c00308   
2020 Penthala NR, Shoeib A, Dachavaram SS, Cabanlong CV, Yang J, Zhan CG, Prather PL, Crooks PA. 7-Azaindolequinuclidinones (7-AIQD): A novel class of cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptor ligands. Bioorganic & Medicinal Chemistry Letters. 30: 127501. PMID 32882418 DOI: 10.1016/j.bmcl.2020.127501   
2020 García-Pedraza JÁ, Morán A, Martín ML, Ollauri-Ibáñez C, Rodríguez-Barbero A, Villalón CM, García-Domingo M. Dopamine D receptor subtype activation reduces the rat cardiac parasympathetic discharge. Pflugers Archiv : European Journal of Physiology. PMID 32820344 DOI: 10.1007/s00424-020-02452-8   
2020 Zhang XY, Soufi S, Dormuth C, Musini VM. Time course for blood pressure lowering of beta-blockers with partial agonist activity. The Cochrane Database of Systematic Reviews. 9: CD010054. PMID 32888198 DOI: 10.1002/14651858.CD010054.pub2   
2020 Spillmann M, Thurner L, Romantini N, Zimmermann M, Meger B, Behe M, Waldhoer M, Schertler GFX, Berger P. New Insights into Arrestin Recruitment to GPCRs. International Journal of Molecular Sciences. 21. PMID 32668755 DOI: 10.3390/ijms21144949   
2020 Daya R, Ho J, Thomson S, Bhandari J, Mishra RK. The Effect of PAOPA, a Novel Allosteric Modulator of Dopamine D2 Receptors, on Select Signaling Proteins Following Sub-Chronic Administration in the Rat. Current Molecular Pharmacology. PMID 32912130 DOI: 10.2174/1874467213666200910091007   
2020 Lillo A, Martínez-Pinilla E, Reyes-Resina I, Navarro G, Franco R. Adenosine A and A Receptors Are Able to Interact with Each Other. A Further Piece in the Puzzle of Adenosine Receptor-Mediated Signaling. International Journal of Molecular Sciences. 21. PMID 32709103 DOI: 10.3390/ijms21145070   
2020 Cifani C, Micioni Di Bonaventura E, Botticelli L, Del Bello F, Giorgioni G, Pavletić P, Piergentili A, Quaglia W, Bonifazi A, Schepmann D, Wünsch B, Vistoli G, Micioni Di Bonaventura MV. Novel Highly Potent and Selective Sigma1 Receptor Antagonists Effectively Blocking the Binge Eating Episode in Female Rats. Acs Chemical Neuroscience. PMID 32886484 DOI: 10.1021/acschemneuro.0c00456   
2020 Zheng M, Zhang X, Min X, Sun N, Kim KM. Cytoplasmic recruitment of Mdm2 as a common characteristic of G protein-coupled receptors that undergo desensitization. Biochemical and Biophysical Research Communications. 530: 181-188. PMID 32828283 DOI: 10.1016/j.bbrc.2020.06.091   
2020 Palma JA, Gupta A, Sierra S, Gomes I, Balgobin B, Norcliffe-Kaufmann L, Devi LA, Kaufmann H. Autoantibodies blocking M muscarinic receptors cause postganglionic cholinergic dysautonomia. Annals of Neurology. PMID 32833276 DOI: 10.1002/ana.25882   
2020 Milliken BT, Doyle RP, Holz GG, Chepurny OG. FRET Reporter Assays for cAMP and Calcium in a 96-well Format Using Genetically Encoded Biosensors Expressed in Living Cells. Bio-Protocol. 10. PMID 32775537 DOI: 10.21769/bioprotoc.3641   
2020 Kumar V, Hoag H, Sader S, Scorese N, Liu H, Wu C. GDP Release from the Open Conformation of Gα Requires Allosteric Signaling from the Agonist-Bound Human β Adrenergic Receptor. Journal of Chemical Information and Modeling. PMID 32786510 DOI: 10.1021/acs.jcim.0c00432   
2020 de la Rosa R, Schlezinger JJ, Smith MT, Webster TF. Application of generalized concentration addition to predict mixture effects of glucocorticoid receptor ligands. Toxicology in Vitro : An International Journal Published in Association With Bibra. 104975. PMID 32858110 DOI: 10.1016/j.tiv.2020.104975   
2020 Motawe ZY, Abdelmaboud SS, Cuevas J, Breslin JW. PRE-084 as a tool to uncover potential therapeutic applications for selective sigma-1 receptor activation. The International Journal of Biochemistry & Cell Biology. 126: 105803. PMID 32668330 DOI: 10.1016/j.biocel.2020.105803   
2020 Gruteser N, Kohlhas V, Balfanz S, Franzen A, Günther A, Offenhäusser A, Müller F, Nikolaev V, Lohse MJ, Baumann A. Establishing a sensitive fluorescence-based quantification method for cyclic nucleotides. Bmc Biotechnology. 20: 47. PMID 32854679 DOI: 10.1186/s12896-020-00633-y   
2020 Drimousis S, Markus I, Murphy TV, Perera DS, Phan-Thien KC, Zhang L, Liu L. Gender-related differences of tachykinin NK receptor expression and activity in human colonic smooth muscle. The Journal of Pharmacology and Experimental Therapeutics. PMID 32764152 DOI: 10.1124/jpet.120.265967   
2020 Huang YJ, Galen K, Zweifel B, Brooks LR, Wright AD. Distinct binding and signaling activity of Acthar Gel compared to other melanocortin receptor agonists. Journal of Receptor and Signal Transduction Research. 1-9. PMID 32938265 DOI: 10.1080/10799893.2020.1818094   
2020 Corrie LW, Stokes C, Wilkerson JL, Carroll FI, McMahon LR, Papke RL. Nicotinic Acetylcholine Receptor Accessory Subunits Determine the Activity Profile of Epibatidine Derivatives. Molecular Pharmacology. PMID 32690626 DOI: 10.1124/molpharm.120.000037   
2020 Jacobson KA, Salmaso V. Purinergic signaling: Impact of GPCR structures on rational drug design. Chemmedchem. PMID 32803849 DOI: 10.1002/cmdc.202000465   
2020 Rukavina Mikusic NL, Silva MG, Pineda AM, Gironacci MM. Angiotensin Receptors Heterodimerization and Trafficking: How Much Do They Influence Their Biological Function? Frontiers in Pharmacology. 11: 1179. PMID 32848782 DOI: 10.3389/fphar.2020.01179   
2020 Friedman S, Tauber M, Ben-Chaim Y. Sodium ions allosterically modulate the M2 muscarinic receptor. Scientific Reports. 10: 11177. PMID 32636499 DOI: 10.1038/s41598-020-68133-9   
2020 Gao C, Zeng J, Jia N, Stavenhagen K, Matsumoto Y, Zhang H, Li J, Hume AJ, Mühlberger E, van Die I, Kwan J, Tantisira K, Emili A, Cummings RD. SARS-CoV-2 Spike Protein Interacts with Multiple Innate Immune Receptors. Biorxiv : the Preprint Server For Biology. PMID 32766577 DOI: 10.1101/2020.07.29.227462   
2020 Greenfield DA, Schmidt HR, Skiba MA, Mandler MD, Anderson JR, Sliz P, Kruse AC. Virtual Screening for Ligand Discovery at the σ Receptor. Acs Medicinal Chemistry Letters. 11: 1555-1561. PMID 32832023 DOI: 10.1021/acsmedchemlett.9b00314   
2020 Hinnah K, Willems S, Morstein J, Heering J, Hartrampf F, Broichhagen J, Leippe P, Merk D, Trauner D. Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor Gamma (PPAR). Journal of Medicinal Chemistry. PMID 32886507 DOI: 10.1021/acs.jmedchem.0c00654   
2020 Holst MR, Nielsen SSE, Nielsen MS. Mapping Receptor Antibody Endocytosis and Trafficking in Brain Endothelial Cells. Methods in Molecular Biology (Clifton, N.J.). PMID 32813236 DOI: 10.1007/7651_2020_312   
2020 Bekker R, Fjellaksel R, Hjornevik T, Nuruddin S, Rafique W, Hansen J, Sundset R, Haraldsen I, Riß PJ. Discovery of a lead brain-penetrating gonadotropin releasing hormone receptor antagonist with saturable binding in brain. Chemmedchem. PMID 32677155 DOI: 10.1002/cmdc.202000256   
2020 Shi JJ, Jia KH, Sun H, Gunosewoyo H, Yang F, Tang J, Luo J, Yu L. Synthesis and pharmacological evaluation of σ2 receptor ligands based on a 3-alkoxyisoxazole scaffold: potential antitumor effects against osteosarcoma. Chemmedchem. PMID 32964625 DOI: 10.1002/cmdc.202000461   
2020 Avgoustou P, Jailani ABA, Zirimwabagabo JO, Tozer MJ, Gibson KR, Glossop PA, Mills JEJ, Porter RA, Blaney P, Bungay PJ, Wang N, Shaw AP, Bigos KJA, Holmes JL, Warrington JI, et al. Discovery of a First-in-Class Potent Small Molecule Antagonist against the Adrenomedullin-2 Receptor. Acs Pharmacology & Translational Science. 3: 706-719. PMID 32832872 DOI: 10.1021/acsptsci.0c00032   
2020 González-Naranjo P, Pérez C, Girón R, Sánchez-Robles EM, Martín-Fontelles MI, Carrillo-López N, Martín-Vírgala J, Naves M, Campillo NE, Páez JA. New cannabinoid receptor antagonists as pharmacological tool. Bioorganic & Medicinal Chemistry. 28: 115672. PMID 32912440 DOI: 10.1016/j.bmc.2020.115672   
2020 Li Z, Luo W, Fang S, Chen X, Lin T, Zhou S, Zhang L, Yang W, Li Z, Jiantao Y, Junjian W, Liu P, Li Z. Prostacyclin facilitates vascular smooth muscle cell phenotypic transformation via activating TP receptors when IP receptors are deficient. Acta Physiologica (Oxford, England). e13555. PMID 32886850 DOI: 10.1111/apha.13555   
2020 Wang GS, Liang A, Dai YB, Wu XL, Sun F. Expression and localization of retinoid receptors in the testis of normal and infertile men. Molecular Reproduction and Development. PMID 32770619 DOI: 10.1002/mrd.23412   
2020 Sarkar P, Jafurulla M, Bhowmick S, Chattopadhyay A. Structural Stringency and Optimal Nature of Cholesterol Requirement in the Function of the Serotonin Receptor. The Journal of Membrane Biology. PMID 32949248 DOI: 10.1007/s00232-020-00138-x   
2020 Uribe-Herranz M, Kuguel SG, Casós K, Costa C. Characterization of putative regulatory isoforms of porcine tumor necrosis factor receptor 2 in endothelial cells. Xenotransplantation. e12635. PMID 32783288 DOI: 10.1111/xen.12635   
2020 Gimeno-Martos S, Santorromán-Nuez M, Cebrián-Pérez JA, Muiño-Blanco T, Pérez-Pé R, Casao A. Involvement of progesterone and estrogen receptors in the ram sperm acrosome reaction. Domestic Animal Endocrinology. 74: 106527. PMID 32799038 DOI: 10.1016/j.domaniend.2020.106527   
2020 Okashah N, Wright SC, Kawakami K, Mathiasen S, Zhou J, Lu S, Javitch JA, Inoue A, Bouvier M, Lambert NA. Agonist-induced formation of unproductive receptor-G complexes. Proceedings of the National Academy of Sciences of the United States of America. PMID 32817560 DOI: 10.1073/pnas.2003787117   
2020 Andrejew R, Oliveira-Giacomelli Á, Ribeiro DE, Glaser T, Arnaud-Sampaio VF, Lameu C, Ulrich H. The P2X7 Receptor: Central Hub of Brain Diseases. Frontiers in Molecular Neuroscience. 13: 124. PMID 32848594 DOI: 10.3389/fnmol.2020.00124   
2020 Sun X, Zhou R, Lei Y, Hu J, Li X. The ligand-gated ion channel P2X7 receptor mediates NLRP3/caspase-1-mediated pyroptosis in cerebral cortical neurons of juvenile rats with sepsis. Brain Research. 147109. PMID 32905819 DOI: 10.1016/j.brainres.2020.147109   
2020 Böttke T, Ernicke S, Serfling R, Ihling C, Burda E, Gurevich VV, Sinz A, Coin I. Exploring GPCR-arrestin interfaces with genetically encoded crosslinkers. Embo Reports. e50437. PMID 32929862 DOI: 10.15252/embr.202050437   
2020 Pismataro MC, Horenstein NA, Stokes C, Quadri M, De Amici M, Papke RL, Dallanoce C. Design, synthesis, and electrophysiological evaluation of NS6740 derivatives: Exploration of the structure-activity relationship for alpha7 nicotinic acetylcholine receptor silent activation. European Journal of Medicinal Chemistry. 205: 112669. PMID 32810771 DOI: 10.1016/j.ejmech.2020.112669   
2020 Gutjahr A, Papagno L, Vernejoul F, Lioux T, Jospin F, Chanut B, Perouzel E, Rochereau N, Appay V, Verrier B, Paul S. New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses. Ebiomedicine. 58: 102922. PMID 32739871 DOI: 10.1016/j.ebiom.2020.102922   
2020 Gutjahr A, Papagno L, Vernejoul F, Lioux T, Jospin F, Chanut B, Perouzel E, Rochereau N, Appay V, Verrier B, Paul S. New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses. Ebiomedicine. 58: 102922. PMID 32739871 DOI: 10.1016/j.ebiom.2020.102922   
2020 Andrade F, Rangel-Sandoval C, Rodríguez-Hernández A, López-Dyck E, Elizalde A, Virgen-Ortiz A, Bonales-Alatorre E, Valencia-Cruz G, Sánchez-Pastor E. Capsaicin Causes Vasorelaxation of Rat Aorta through Blocking of L-type Ca Channels and Activation of CB Receptors. Molecules (Basel, Switzerland). 25. PMID 32872656 DOI: 10.3390/molecules25173957   
2020 Pilli VS, Datta A, Dorsey A, Liu B, Majumder R. Modulation of protein S and growth arrest specific 6 protein signaling inhibits pancreatic cancer cell survival and proliferation. Oncology Reports. PMID 32945517 DOI: 10.3892/or.2020.7689   
2020 Oliveira da Cruz JF, Ioannidou C, Pagano Zottola AC, Muguruza C, Gomez-Sotres P, Fernandez M, Callado LF, Marsicano G, Busquets-Garcia A. Sex-dependent pharmacological profiles of the synthetic cannabinoid MMB-Fubinaca. Addiction Biology. e12940. PMID 32744799 DOI: 10.1111/adb.12940   
2020 Reed AB, Lanman BA, Ryan Holder J, Yang BH, Ma J, Humphreys SC, Wang Z, C Y Chan J, Miranda LP, Swaminath G, Allen JG. Half-life extension of peptidic APJ agonists by N-terminal lipid conjugation. Bioorganic & Medicinal Chemistry Letters. 127499. PMID 32858124 DOI: 10.1016/j.bmcl.2020.127499   
2020 Ellaithy A, Gonzalez-Maeso J, Logothetis DA, Levitz J. Structural and Biophysical Mechanisms of Class C G Protein-Coupled Receptor Function. Trends in Biochemical Sciences. PMID 32861513 DOI: 10.1016/j.tibs.2020.07.008