Kurt Harald Backus, Prof. - Related publications

Affiliations: 
Physiology Goethe-Universität Frankfurt am Main, Frankfurt am Main, Hessen, Germany 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Athapaththu AMGK, Molagoda IMN, Jayasooriya RGPT, Choi YH, Jeon YJ, Park JH, Lee BJ, Kim GY. Gamma-Aminobutyric Acid (GABA) Promotes Growth in Zebrafish Larvae by Inducing IGF-1 Expression via GABA and GABA Receptors. International Journal of Molecular Sciences. 22. PMID 34681914 DOI: 10.3390/ijms222011254   
2021 Bony AR, McArthur JR, Finol-Urdaneta RK, Adams DJ. Analgesic α-conotoxins modulate native and recombinant GIRK1/2 channels via GABA receptor activation and reduce neuroexcitability. British Journal of Pharmacology. PMID 34599513 DOI: 10.1111/bph.15690   
2021 Lin TY, Lu CW, Hsieh PW, Chiu KM, Lee MY, Wang SJ. Natural Product Isoliquiritigenin Activates GABA Receptors to Decrease Voltage-Gate Ca Channels and Glutamate Release in Rat Cerebrocortical Nerve Terminals. Biomolecules. 11. PMID 34680170 DOI: 10.3390/biom11101537   
2021 Sexton CA, Penzinger R, Mortensen M, Bright DP, Smart TG. Structural determinants and regulation of spontaneous activity in GABA receptors. Nature Communications. 12: 5457. PMID 34526505 DOI: 10.1038/s41467-021-25633-0   
2021 Xue C, Ng IS. Sustainable production of 4-aminobutyric acid (GABA) and cultivation of Chlorella sorokiniana and Chlorella vulgaris as circular economy. Bioresource Technology. 126089. PMID 34624471 DOI: 10.1016/j.biortech.2021.126089   
2021 Bassetti D, Luhmann HJ, Kirischuk S. Presynaptic GABA receptor-mediated network excitation in the medial prefrontal cortex of Tsc2 mice. Pflugers Archiv : European Journal of Physiology. 473: 1261-1271. PMID 34279736 DOI: 10.1007/s00424-021-02576-5   
2021 Lengu K, Ryan S, Peltier SJ, Tyszkowski T, Kairys A, Giordani B, Hampstead BM. Effects of High Definition-Transcranial Direct Current Stimulation on Local GABA and Glutamate Levels Among Older Adults with and without Mild Cognitive Impairment: An Exploratory Study. Journal of Alzheimer's Disease : Jad. PMID 34602464 DOI: 10.3233/JAD-201091   
2021 Hou J, Abie SM, Strand-Amundsen R, Galperin YM, Bergli J, Schuelke C, Hashemizadeh S, Martinsen ØG. Temperature dependence of the microwave dielectric properties of [Formula: see text]-aminobutyric acid. Scientific Reports. 11: 18082. PMID 34508109 DOI: 10.1038/s41598-021-97178-7   
2021 Sueviriyapan N, Granados-Fuentes D, Simon T, Herzog ED, Henson MA. Modelling the functional roles of synaptic and extra-synaptic γ-aminobutyric acid receptor dynamics in circadian timekeeping. Journal of the Royal Society, Interface. 18: 20210454. PMID 34520693 DOI: 10.1098/rsif.2021.0454   
2021 Jiang X, Xu Q, Zhang A, Liu Y, Zhao L, Gu L, Yuan J, Jia H, Shen X, Li Z, Cao D, Zhang D. Optimization of γ-Aminobutyric Acid (GABA) Accumulation in Germinating Adzuki Beans () by Vacuum Treatment and Monosodium Glutamate, and the Molecular Mechanisms. Frontiers in Nutrition. 8: 693862. PMID 34568402 DOI: 10.3389/fnut.2021.693862   
2021 Coquerel QRR, Démares F, Geldenhuys WJ, Le Ray AM, Bréard D, Richomme P, Legros C, Norris E, Bloomquist JR. Toxicon Toxicity and mode of action of the aporphine plant alkaloid liriodenine on the insect GABA receptor. Toxicon : Official Journal of the International Society On Toxinology. PMID 34474068 DOI: 10.1016/j.toxicon.2021.08.019   
2021 Nikolaev MV, Strashkov DM, Ryazantsev MN, Tikhonov DB. Optical Control of -Methyl-d-aspartate Receptors by Azobenzene Quaternary Ammonium Compounds. Acs Chemical Neuroscience. PMID 34469111 DOI: 10.1021/acschemneuro.1c00310   
2021 Costa BM, Kwapisz LC, Mehrkens B, Bledsoe DN, Vacca BN, Johnston TV, Razzaq R, Manickam D, Klein BG. A glutamate concentration-biased allosteric modulator potentiates NMDA-induced ion influx in neurons. Pharmacology Research & Perspectives. 9: e00859. PMID 34476911 DOI: 10.1002/prp2.859   
2021 Park MG, Han AR, Kim SY, Kim TY, Kim HM, Lee CJ. High-yield synthesis and purification of recombinant human GABA transaminase for high-throughput screening assays. Journal of Enzyme Inhibition and Medicinal Chemistry. 36: 2016-2024. PMID 34514924 DOI: 10.1080/14756366.2021.1975697   
2021 Bhattacharya D, Gawali VS, Kallay L, Toukam DK, Koehler A, Stambrook P, Krummel DP, Sengupta S. Therapeutically leveraging GABA receptors in cancer. Experimental Biology and Medicine (Maywood, N.J.). 246: 2128-2135. PMID 34649481 DOI: 10.1177/15353702211032549   
2021 Badri H, LGibbard C, Denton D, Satia I, Dockry RJ, Holt K, Escott J, Wilkinson G, Holt A, Canning BJ, Smith JA. Effect of centrally and peripherally acting GABA agonism on the healthy human cough reflex. Pulmonary Pharmacology & Therapeutics. 102079. PMID 34571095 DOI: 10.1016/j.pupt.2021.102079   
2021 Foliaki ST, Schwarz B, Groveman BR, Walters RO, Ferreira NC, Orrù CD, Smith A, Wood A, Schmit OM, Freitag P, Yuan J, Zou W, Bosio CM, Carroll JA, Haigh CL. Neuronal excitatory-to-inhibitory balance is altered in cerebral organoid models of genetic neurological diseases. Molecular Brain. 14: 156. PMID 34635127 DOI: 10.1186/s13041-021-00864-w   
2021 Jiang J, Tang B, Wang L, Huo Q, Tan S, Misrani A, Han Y, Li H, Hu H, Wang J, Cheng T, Tabassum S, Chen M, Xie W, Long C, et al. Systemic LPS-induced microglial activation results in increased GABAergic tone: a mechanism of protection against neuroinflammation in the medial prefrontal cortex in mice. Brain, Behavior, and Immunity. PMID 34582995 DOI: 10.1016/j.bbi.2021.09.017   
2021 Borroto-Escuela DO, Ferraro L, Beggiato S, Narváez M, Fores-Pons R, Alvarez-Contino JE, Wydra K, Frankowska M, Bader M, Filip M, Fuxe K. The coming together of allosteric and phosphorylation mechanisms in the molecular integration of A2A heteroreceptor complexes in the dorsal and ventral striatal-pallidal GABA neurons. Pharmacological Reports : Pr. PMID 34426901 DOI: 10.1007/s43440-021-00314-3   
2021 Wang X, Sun X, Zhou HC, Luo F. Activation of β3-adrenoceptor increases the number of readily releasable glutamatergic vesicle via activating Ca/calmodulin/MLCK/myosin II pathway in the prefrontal cortex of juvenile rats. Scientific Reports. 11: 18300. PMID 34526598 DOI: 10.1038/s41598-021-97769-4   
2021 Bao Y, Yang X, Fu Y, Li Z, Gong R, Lu W. NMDAR-dependent somatic potentiation of synaptic inputs is correlated with β amyloid-mediated neuronal hyperactivity. Translational Neurodegeneration. 10: 34. PMID 34496956 DOI: 10.1186/s40035-021-00260-3   
2021 Takahashi Y, Yamashita R, Okano H, Takashima K, Ogawa B, Ojiro R, Tang Q, Ozawa S, Woo GH, Yoshida T, Shibutani M. Aberrant neurogenesis and late onset suppression of synaptic plasticity as well as sustained neuroinflammation in the hippocampal dentate gyrus after developmental exposure to ethanol in rats. Toxicology. 152958. PMID 34547370 DOI: 10.1016/j.tox.2021.152958   
2021 Malhotra S, Banumurthy G, Pennock R, Vaden JH, Sugihara I, Overstreet-Wadiche L, Wadiche JI. Climbing fiber-mediated spillover transmission to interneurons is regulated by EAAT4. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34400517 DOI: 10.1523/JNEUROSCI.0616-21.2021   
2021 Wilson CS, Dohare P, Orbeta S, Nalwalk JW, Huang Y, Ferland RJ, Sah R, Scimemi A, Mongin AA. Late adolescence mortality in mice with brain-specific deletion of the volume-regulated anion channel subunit LRRC8A. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21869. PMID 34469026 DOI: 10.1096/fj.202002745R   
2021 Yoon SH, Song WS, Oh SP, Kim YS, Kim MH. The phosphorylation status of eukaryotic elongation factor-2 indicates neural activity in the brain. Molecular Brain. 14: 142. PMID 34526091 DOI: 10.1186/s13041-021-00852-0   
2021 Chang A, Hung CF, Hsieh PW, Ko HH, Wang SJ. Eupafolin Suppresses P/Q-Type Ca Channels to Inhibit Ca/ Calmodulin-Dependent Protein Kinase II and Glutamate Release at Rat Cerebrocortical Nerve Terminals. Biomolecules & Therapeutics. PMID 34475273 DOI: 10.4062/biomolther.2021.046   
2021 Racine AS, Michon FX, Laplante I, Lacaille JC. Somatostatin contributes to long-term potentiation at excitatory synapses onto hippocampal somatostatinergic interneurons. Molecular Brain. 14: 130. PMID 34429141 DOI: 10.1186/s13041-021-00830-6   
2021 Liu Y, Ding S, Luan Y, Zhu Z, Cai Y, Liu Y. Ginkgo biloba extracts inhibit post-ischemic LTP through attenuating EPSCs in rat hippocampus. Metabolic Brain Disease. PMID 34463942 DOI: 10.1007/s11011-021-00830-4   
2021 Moroz LL, Nikitin MA, Poličar PG, Kohn AB, Romanova DY. Evolution of glutamatergic signaling and synapses. Neuropharmacology. 108740. PMID 34343611 DOI: 10.1016/j.neuropharm.2021.108740   
2021 Iizumi M, Oota-Ishigaki A, Yamashita M, Hayashi T. Reduced Effect of Anticonvulsants on AMPA Receptor Palmitoylation-Deficient Mice. Frontiers in Pharmacology. 12: 711737. PMID 34483921 DOI: 10.3389/fphar.2021.711737   
2021 Zhu Y, Armstrong JN, Contractor A. Kainate receptors regulate the functional properties of young adult-born dentate granule cells. Cell Reports. 36: 109751. PMID 34551304 DOI: 10.1016/j.celrep.2021.109751   
2021 Rozov SV, Rosenholm M, Hintikka S, Rantamäki T. Tianeptine induces expression of dual specificity phosphatases and evokes rebound emergence of cortical slow wave electrophysiological activity. Neuroscience Letters. 764: 136200. PMID 34464676 DOI: 10.1016/j.neulet.2021.136200   
2021 Negri S, Faris P, Maniezzi C, Pellavio G, Spaiardi P, Botta L, Laforenza U, Biella G, Moccia DF. NMDA receptors elicit flux-independent intracellular Ca signals via metabotropic glutamate receptors and flux-dependent nitric oxide release in human brain microvascular endothelial cells. Cell Calcium. 99: 102454. PMID 34454368 DOI: 10.1016/j.ceca.2021.102454   
2021 Kadgien CA, Kamesh A, Milnerwood AJ. Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition. Molecular Brain. 14: 143. PMID 34530877 DOI: 10.1186/s13041-021-00848-w   
2021 Yu H, Bai XC, Wang W. Characterization of the subunit composition and structure of adult human glycine receptors. Neuron. 109: 2707-2716.e6. PMID 34473954 DOI: 10.1016/j.neuron.2021.08.019   
2021 Van Den Herrewegen Y, Sanderson TM, Sahu S, De Bundel D, Bortolotto ZA, Smolders I. Side-by-side comparison of the effects of Gq- and Gi-DREADD-mediated astrocyte modulation on intracellular calcium dynamics and synaptic plasticity in the hippocampal CA1. Molecular Brain. 14: 144. PMID 34544455 DOI: 10.1186/s13041-021-00856-w   
2021 Lee BJ, Yang CH, Lee SY, Lee SH, Kim Y, Ho WK. Voltage-gated calcium channels contribute to spontaneous glutamate release directly via nanodomain coupling or indirectly via calmodulin. Progress in Neurobiology. 102182. PMID 34695543 DOI: 10.1016/j.pneurobio.2021.102182   
2021 Gómez R, Maglio LE, Gonzalez-Hernandez AJ, Rivero-Pérez B, Bartolomé-Martín D, Giraldez T. NMDA receptor-BK channel coupling regulates synaptic plasticity in the barrel cortex. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34453004 DOI: 10.1073/pnas.2107026118   
2021 Stachowicz K, Bobula B, Kusek M, Lenda T, Tokarski K. Evidence for the interaction of COX-2 with mGluR5 in the regulation of EAAT1 and EAAT3 protein levels in the mouse hippocampus. The influence of oxidative stress mechanisms. Brain Research. 1771: 147660. PMID 34529964 DOI: 10.1016/j.brainres.2021.147660   
2021 Miao Y, Chen X, You F, Jia M, Li T, Tang P, Shi R, Hu S, Zhang L, Chen JF, Gao Y. Adenosine A receptor modulates microglia-mediated synaptic pruning of the retinogeniculate pathway during postnatal development. Neuropharmacology. 108806. PMID 34562441 DOI: 10.1016/j.neuropharm.2021.108806   
2021 Yang L, Wang Y, Chen Z. Central Histaminergic Signaling, Neural Excitability and Epilepsy. British Journal of Pharmacology. PMID 34599508 DOI: 10.1111/bph.15692   
2021 Geoffroy C, Paoletti P, Mony L. Positive allosteric modulation of NMDA receptors: mechanisms, physiological impact and therapeutic potential. The Journal of Physiology. PMID 34339523 DOI: 10.1113/JP280875   
2021 Goulart VG, Rocha-Mendonça H, Maisonnette S, Pandolfo P, Landeira-Fernandez J, Campello-Costa P. Differential expression of glutamatergic receptor subunits in the hippocampus in carioca high- and low-conditioned freezing rats. Molecular and Cellular Neurosciences. 103666. PMID 34464708 DOI: 10.1016/j.mcn.2021.103666   
2021 Miao HH, Miao Z, Pan JG, Li XH, Zhuo M. Brain-derived neurotrophic factor produced long-term synaptic enhancement in the anterior cingulate cortex of adult mice. Molecular Brain. 14: 140. PMID 34526080 DOI: 10.1186/s13041-021-00853-z   
2021 Huang SK, Lu CW, Lin TY, Wang SJ. Neuroprotective Role of the B Vitamins in the Modulation of the Central Glutamatergic Neurotransmission. Cns & Neurological Disorders Drug Targets. PMID 34477538 DOI: 10.2174/1871527320666210902165739   
2021 Vibholm AK, Dietz MJ, Beniczky S, Christensen J, Højlund A, Jacobsen J, Bender D, Møller A, Brooks DJ. Activated N-methyl-D-aspartate receptor ion channels detected in focal epilepsy with [ F]GE-179 positron emission tomography. Epilepsia. PMID 34558066 DOI: 10.1111/epi.17074   
2021 Xia P, Zheng Y, Dong L, Tian C. Short-Term Extremely Low-Frequency Electromagnetic Field Inhibits Synaptic Plasticity of Schaffer Collateral-CA1 Synapses in Rat Hippocampus via the Ca/Calcineurin Pathway. Acs Chemical Neuroscience. PMID 34498467 DOI: 10.1021/acschemneuro.1c00500   
2021 Yao H, Liu W, Liao H, Sheng T, Chen P, Zhou H, Pan Y, Xie J, Zhang Q, Zou Z, Chen Z. Geniposide attenuates postischemic long-term potentiation via GluN2A. Pakistan Journal of Pharmaceutical Sciences. 34: 909-914. PMID 34602413   
2021 Lee J, Kwag J. Activation of PLCβ1 enhances endocannabinoid mobilization to restore hippocampal spike-timing-dependent potentiation and contextual fear memory impaired by Alzheimer's amyloidosis. Alzheimer's Research & Therapy. 13: 165. PMID 34625112 DOI: 10.1186/s13195-021-00901-9   
2021 Green JL, Dos Santos WF, Fontana ACK. Role of glutamate excitotoxicity and glutamate transporter EAAT2 in epilepsy: opportunities for novel therapeutics development. Biochemical Pharmacology. 114786. PMID 34571003 DOI: 10.1016/j.bcp.2021.114786