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Hisashi Fujioka, PhD - Publications

Pathology Case Western Reserve University, Cleveland Heights, OH, United States 

121 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Han S, Zhao F, Hsia J, Ma X, Liu Y, Torres S, Fujioka H, Zhu X. The role of Mfn2 in the structure and function of ER-mitochondrial tethering in vivo. Journal of Cell Science. PMID 34110411 DOI: 10.1242/jcs.253443  0.84
2021 Niu M, Zhao F, Bondelid K, Siedlak SL, Torres S, Fujioka H, Wang W, Liu J, Zhu X. VPS35 D620N knockin mice recapitulate cardinal features of Parkinson's disease. Aging Cell. e13347. PMID 33745227 DOI: 10.1111/acel.13347  0.92
2020 Yan T, Liang J, Gao J, Wang L, Fujioka H, Zhu X, Wang X. FAM222A encodes a protein which accumulates in plaques in Alzheimer's disease. Nature Communications. 11: 411. PMID 31964863 DOI: 10.1038/S41467-019-13962-0  0.84
2020 Han S, Nandy P, Austria Q, Siedlak SL, Torres S, Fujioka H, Wang W, Zhu X. Mfn2 Ablation in the Adult Mouse Hippocampus and Cortex Causes Neuronal Death. Cells. 9. PMID 31947766 DOI: 10.3390/Cells9010116  0.92
2019 Liu Y, Ma X, Fujioka H, Liu J, Chen S, Zhu X. DJ-1 regulates the integrity and function of ER-mitochondria association through interaction with IP3R3-Grp75-VDAC1. Proceedings of the National Academy of Sciences of the United States of America. PMID 31767755 DOI: 10.1073/Pnas.1906565116  0.84
2018 Wang L, Gao J, Liu J, Siedlak SL, Torres S, Fujioka H, Huntley ML, Jiang Y, Ji H, Yan T, Harland M, Termsarasab P, Zeng S, Jiang Z, Liang J, et al. Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles. Cell Metabolism. PMID 30017354 DOI: 10.1016/J.Cmet.2018.06.011  0.92
2018 Jiang S, Nandy P, Wang W, Ma X, Hsia J, Wang C, Wang Z, Niu M, Siedlak SL, Torres S, Fujioka H, Xu Y, Lee HG, Perry G, Liu J, et al. Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex. Molecular Neurodegeneration. 13: 5. PMID 29391029 DOI: 10.1186/S13024-018-0238-8  0.92
2017 Abskharon R, Dang J, Elfarash A, Wang Z, Shen P, Zou LS, Hassan S, Wang F, Fujioka H, Steyaert J, Mulaj M, Surewicz WK, Castilla J, Wohlkonig A, Zou WQ. Soluble polymorphic bank vole prion proteins induced by co-expression of quiescin sulfhydryl oxidase in E. coli and their aggregation behaviors. Microbial Cell Factories. 16: 170. PMID 28978309 DOI: 10.1186/S12934-017-0782-X  0.48
2017 Wang W, Yin J, Ma X, Zhao F, Siedlak SL, Wang Z, Fujioka H, Xu Y, Perry G, Zhu X. Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model. Human Molecular Genetics. PMID 28973308 DOI: 10.1093/Hmg/Ddx299  0.92
2017 Zhao F, Wang W, Wang C, Siedlak SL, Fujioka H, Tang B, Zhu X. Mfn2 Protects Dopaminergic Neurons Exposed to Paraquat Both in vitro and in vivo: Implications for Idiopathic Parkinson's Disease. Biochimica Et Biophysica Acta. PMID 28215578 DOI: 10.1016/J.Bbadis.2017.02.016  0.92
2016 Wang W, Wang L, Lu J, Siedlak SL, Fujioka H, Liang J, Jiang S, Ma X, Jiang Z, da Rocha EL, Sheng M, Choi H, Lerou PH, Li H, Wang X. The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity. Nature Medicine. PMID 27348499 DOI: 10.1038/Nm.4130  0.32
2016 Sakaguchi M, Miyazaki N, Fujioka H, Kaneko O, Murata K. Three-dimensional analysis of morphological changes in the malaria parasite infected red blood cell by serial block-face scanning electron microscopy. Journal of Structural Biology. PMID 26772147 DOI: 10.1016/J.Jsb.2016.01.003  0.92
2015 Wang W, Wang X, Fujioka H, Hoppel C, Whone AL, Caldwell MA, Cullen PJ, Liu J, Zhu X. Parkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes. Nature Medicine. PMID 26618722 DOI: 10.1038/Nm.3983  0.32
2015 Tandler B, Fujioka H, Hoppel CL, Haldar SM, Jain MK. Megamitochondria in Cardiomyocytes of a Knockout (Klf15-/-) Mouse. Ultrastructural Pathology. 1-4. PMID 26111268 DOI: 10.3109/01913123.2015.1042610  0.92
2015 Xiao X, Cali I, Yuan J, Cracco L, Curtiss P, Zeng L, Abouelsaad M, Gazgalis D, Wang GX, Kong Q, Fujioka H, Puoti G, Zou WQ. Synthetic Aβ peptides acquire prion-like properties in the brain. Oncotarget. 6: 642-50. PMID 25460507 DOI: 10.18632/Oncotarget.2819  0.36
2015 Wang W, Zhang F, Li L, Tang F, Siedlak SL, Fujioka H, Liu Y, Su B, Pi Y, Wang X. MFN2 couples glutamate excitotoxicity and mitochondrial dysfunction in motor neurons. The Journal of Biological Chemistry. 290: 168-82. PMID 25416777 DOI: 10.1074/Jbc.M114.617167  0.32
2014 Fujioka H, Tandler B, Cohen M, Koontz D, Hoppel CL. Multiple mitochondrial alterations in a case of myopathy. Ultrastructural Pathology. 38: 204-10. PMID 24579828 DOI: 10.3109/01913123.2014.888114  0.92
2014 Solinas P, Fujioka H, Radivoyevitch T, Tandler B, Hoppel CL. Aging effects on oxidative phosphorylation in rat adrenocortical mitochondria. Mechanisms of Ageing and Development. 138: 10-4. PMID 24486556 DOI: 10.1016/J.Mad.2014.01.009  0.92
2014 Prosdocimo DA, Anand P, Liao X, Zhu H, Shelkay S, Artero-Calderon P, Zhang L, Kirsh J, Moore D, Rosca MG, Vazquez E, Kerner J, Akat KM, Williams Z, Zhao J, ... Fujioka H, et al. Kruppel-like factor 15 is a critical regulator of cardiac lipid metabolism. The Journal of Biological Chemistry. 289: 5914-24. PMID 24407292 DOI: 10.1074/Jbc.M113.531384  0.92
2014 Li Q, Hakimi P, Liu X, Yu WM, Ye F, Fujioka H, Raza S, Shankar E, Tang F, Dunwoodie SL, Danielpour D, Hoppel CL, Ramírez-Bergeron DL, Qu CK, Hanson RW, et al. Cited2, a transcriptional modulator protein, regulates metabolism in murine embryonic stem cells. The Journal of Biological Chemistry. 289: 251-63. PMID 24265312 DOI: 10.1074/Jbc.M113.497594  0.92
2014 Fujioka H, Tandler B, Rosca M, McCandless SE, Katirji B, Cohen ML, Rapisuwon S, Hoppel CL. Multiple muscle cell alterations in a case of encephalomyopathy. Ultrastructural Pathology. 38: 13-25. PMID 24134831 DOI: 10.3109/01913123.2013.831158  0.92
2014 Du J, Li Q, Tang F, Puchowitz MA, Fujioka H, Dunwoodie SL, Danielpour D, Yang YC. Cited2 is required for the maintenance of glycolytic metabolism in adult hematopoietic stem cells. Stem Cells and Development. 23: 83-94. PMID 24083546 DOI: 10.1182/Blood.V122.21.794.794  0.92
2013 Gao XH, Qanungo S, Pai HV, Starke DW, Steller KM, Fujioka H, Lesnefsky EJ, Kerner J, Rosca MG, Hoppel CL, Mieyal JJ. Aging-dependent changes in rat heart mitochondrial glutaredoxins--Implications for redox regulation. Redox Biology. 1: 586-98. PMID 25126518 DOI: 10.1016/J.Redox.2013.10.010  0.92
2013 Fujioka H, Phelix CF, Friedland RP, Zhu X, Perry EA, Castellani RJ, Perry G. Apolipoprotein E4 prevents growth of malaria at the intraerythrocyte stage: implications for differences in racial susceptibility to Alzheimer's disease. Journal of Health Care For the Poor and Underserved. 24: 70-8. PMID 24241262 DOI: 10.1353/Hpu.2014.0009  0.92
2013 Fujioka H, Tandler B, Consolo MC, Karnik P. Division of mitochondria in cultured human fibroblasts. Microscopy Research and Technique. 76: 1213-6. PMID 24009193 DOI: 10.1002/Jemt.22287  0.92
2013 Fujioka H, Tandler B, Haldar SM, Jain MK, Hoppel CL. String mitochondria in mouse soleus muscle. Microscopy Research and Technique. 76: 237-41. PMID 23174930 DOI: 10.1002/Jemt.22158  0.92
2013 Liu J, Kobayashi A, Ueno K, Ohta J, Fujioka H, Oshima M. Band configuration of SiO2/m-plane ZnO heterointerface correlated with electrical properties of Al/SiO2/ZnO structures Japanese Journal of Applied Physics. 52. DOI: 10.7567/JJAP.52.011101  0.84
2012 Solinas P, Fujioka H, Tandler B, Hoppel CL. Isolation of rat adrenocortical mitochondria. Biochemical and Biophysical Research Communications. 427: 96-9. PMID 22982630 DOI: 10.1016/J.Bbrc.2012.09.014  0.92
2012 Fujioka H, Tandler B, Hoppel CL. Mitochondrial division in rat cardiomyocytes: an electron microscope study. Anatomical Record (Hoboken, N.J. : 2007). 295: 1455-61. PMID 22753088 DOI: 10.1016/J.Mito.2011.03.096  0.92
2012 Haldar SM, Jeyaraj D, Anand P, Zhu H, Lu Y, Prosdocimo DA, Eapen B, Kawanami D, Okutsu M, Brotto L, Fujioka H, Kerner J, Rosca MG, McGuinness OP, Snow RJ, et al. Kruppel-like factor 15 regulates skeletal muscle lipid flux and exercise adaptation. Proceedings of the National Academy of Sciences of the United States of America. 109: 6739-44. PMID 22493257 DOI: 10.1073/Pnas.1121060109  0.92
2012 Wang X, Petrie TG, Liu Y, Liu J, Fujioka H, Zhu X. Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction. Journal of Neurochemistry. 121: 830-9. PMID 22428580 DOI: 10.1111/J.1471-4159.2012.07734.X  0.92
2012 Agnello M, Benussi L, Bertani M, Bhang HC, Bonomi G, Botta E, Bregant M, Bressani T, Bufalino S, Busso L, Calvo D, Camerini P, Dalena B, De Mori F, D'Erasmo G, ... ... Fujioka H, et al. Evidence for heavy hyperhydrogen (Λ)(6)h. Physical Review Letters. 108: 042501. PMID 22400828  0.44
2012 Wang X, Yan MH, Fujioka H, Liu J, Wilson-Delfosse A, Chen SG, Perry G, Casadesus G, Zhu X. LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1. Human Molecular Genetics. 21: 1931-44. PMID 22228096 DOI: 10.1093/Hmg/Dds003  0.92
2012 Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PL, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G. Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover. Free Radical Biology & Medicine. 52: 699-704. PMID 22137893 DOI: 10.1016/J.Freeradbiomed.2011.11.004  0.92
2011 Zou RS, Fujioka H, Guo JP, Xiao X, Shimoji M, Kong C, Chen C, Tasnadi M, Voma C, Yuan J, Moudjou M, Laude H, Petersen RB, Zou WQ. Characterization of spontaneously generated prion-like conformers in cultured cells. Aging. 3: 968-84. PMID 21990137  0.92
2011 Fujioka H, Moghaddas S, Murdock DG, Lesnefsky EJ, Tandler B, Hoppel CL. Decreased cytochrome c oxidase subunit VIIa in aged rat heart mitochondria: immunocytochemistry. Anatomical Record (Hoboken, N.J. : 2007). 294: 1825-33. PMID 21972221 DOI: 10.1002/Ar.21486  0.92
2011 Ye F, Lemieux H, Hoppel CL, Hanson RW, Hakimi P, Croniger CM, Puchowicz M, Anderson VE, Fujioka H, Stavnezer E. Peroxisome proliferator-activated receptor γ (PPARγ) mediates a Ski oncogene-induced shift from glycolysis to oxidative energy metabolism. The Journal of Biological Chemistry. 286: 40013-24. PMID 21917928 DOI: 10.1074/Jbc.M111.292029  0.92
2011 Amaratunga C, Lopera-Mesa TM, Brittain NJ, Cholera R, Arie T, Fujioka H, Keefer JR, Fairhurst RM. A role for fetal hemoglobin and maternal immune IgG in infant resistance to Plasmodium falciparum malaria. Plos One. 6: e14798. PMID 21532754 DOI: 10.1371/Journal.Pone.0014798  0.92
2011 Zou WQ, Xiao X, Yuan J, Puoti G, Fujioka H, Wang X, Richardson S, Zhou X, Zou R, Li S, Zhu X, McGeer PL, McGeehan J, Kneale G, Rincon-Limas DE, et al. Amyloid-beta42 interacts mainly with insoluble prion protein in the Alzheimer brain. The Journal of Biological Chemistry. 286: 15095-105. PMID 21393248 DOI: 10.1074/Jbc.M110.199356  0.92
2010 Jenkins MW, Duke AR, Gu S, Chiel HJ, Fujioka H, Watanabe M, Jansen ED, Rollins AM. Optical pacing of the embryonic heart. Nature Photonics. 4: 623-626. PMID 21423854 DOI: 10.1038/Nphoton.2010.166  0.92
2010 Lemieux H, Vazquez EJ, Fujioka H, Hoppel CL. Decrease in mitochondrial function in rat cardiac permeabilized fibers correlates with the aging phenotype. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 65: 1157-64. PMID 20801909 DOI: 10.1093/Gerona/Glq141  0.92
2010 Kim J, Fujioka H, Oleinick NL, Anderson VE. Photosensitization of intact heart mitochondria by the phthalocyanine Pc 4: Correlation of structural and functional deficits with cytochrome c release. Free Radical Biology & Medicine. 49: 726-32. PMID 20510354 DOI: 10.1016/J.Freeradbiomed.2010.05.013  0.92
2010 O'Toole JF, Liu Y, Davis EE, Westlake CJ, Attanasio M, Otto EA, Seelow D, Nurnberg G, Becker C, Nuutinen M, Kärppä M, Ignatius J, Uusimaa J, Pakanen S, Jaakkola E, ... ... Fujioka H, et al. Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy. The Journal of Clinical Investigation. 120: 791-802. PMID 20179356 DOI: 10.1172/Jci40076  0.92
2010 O'Toole JF, Patel HV, Naples CJ, Fujioka H, Hoppel CL. Decreased cytochrome c mediates an age-related decline of oxidative phosphorylation in rat kidney mitochondria. The Biochemical Journal. 427: 105-12. PMID 20100174 DOI: 10.1042/Bj20091373  0.92
2010 O'Toole JF, Liu Y, Davis EE, Westlake CJ, Attanasio M, Otto EA, Seelow D, Nurnberg G, Becker C, Nuutinen M, Kärppä M, Ignatius J, Uusimaa J, Pakanen S, Jaakkola E, ... ... Fujioka H, et al. Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy (Journal of Clinical Investigation (2010) 120, 3 (791-802) DOI: 10.1172/JCI40076) Journal of Clinical Investigation. 120: 1362. DOI: 10.1172/Jci40076C1  0.92
2009 Lee HG, Chen Q, Wolfram JA, Richardson SL, Liner A, Siedlak SL, Zhu X, Ziats NP, Fujioka H, Felsher DW, Castellani RJ, Valencik ML, McDonald JA, Hoit BD, Lesnefsky EJ, et al. Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure. Plos One. 4: e7172. PMID 19779629 DOI: 10.1371/Journal.Pone.0007172  0.92
2009 Hoppel CL, Tandler B, Fujioka H, Riva A. Dynamic organization of mitochondria in human heart and in myocardial disease. The International Journal of Biochemistry & Cell Biology. 41: 1949-56. PMID 19446651 DOI: 10.1016/J.Biocel.2009.05.004  0.92
2009 Tsarukyanova I, Drazba JA, Fujioka H, Yadav SP, Sam-Yellowe TY. Proteins of the Plasmodium falciparum two transmembrane Maurer's cleft protein family, PfMC-2TM, and the 130 kDa Maurer's cleft protein define different domains of the infected erythrocyte intramembranous network. Parasitology Research. 104: 875-91. PMID 19130087 DOI: 10.1007/S00436-008-1270-3  0.92
2008 Wang X, Su B, Siedlak SL, Moreira PI, Fujioka H, Wang Y, Casadesus G, Zhu X. Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proceedings of the National Academy of Sciences of the United States of America. 105: 19318-23. PMID 19050078 DOI: 10.1073/Pnas.0804871105  0.92
2008 Mahajan B, Selvapandiyan A, Gerald NJ, Majam V, Zheng H, Wickramarachchi T, Tiwari J, Fujioka H, Moch JK, Kumar N, Aravind L, Nakhasi HL, Kumar S. Centrins, cell cycle regulation proteins in human malaria parasite Plasmodium falciparum. The Journal of Biological Chemistry. 283: 31871-83. PMID 18693242 DOI: 10.1074/Jbc.M800028200  0.92
2008 Sam-Yellowe TY, Banks TL, Fujioka H, Drazba JA, Yadav SP. Plasmodium yoelii: novel rhoptry proteins identified within the body of merozoite rhoptries in rodent Plasmodium malaria. Experimental Parasitology. 120: 113-7. PMID 18606406 DOI: 10.1016/J.Exppara.2008.05.001  0.92
2008 Wang X, Su B, Fujioka H, Zhu X. Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients. The American Journal of Pathology. 173: 470-82. PMID 18599615 DOI: 10.2353/Ajpath.2008.071208  0.92
2008 Rennison JH, McElfresh TA, Okere IC, Patel HV, Foster AB, Patel KK, Stoll MS, Minkler PE, Fujioka H, Hoit BD, Young ME, Hoppel CL, Chandler MP. Enhanced acyl-CoA dehydrogenase activity is associated with improved mitochondrial and contractile function in heart failure. Cardiovascular Research. 79: 331-40. PMID 18339649 DOI: 10.1093/Cvr/Cvn066  0.92
2008 Srinivasan P, Fujioka H, Jacobs-Lorena M. PbCap380, a novel oocyst capsule protein, is essential for malaria parasite survival in the mosquito. Cellular Microbiology. 10: 1304-12. PMID 18248630 DOI: 10.1111/J.1462-5822.2008.01127.X  0.92
2008 Cholera R, Brittain NJ, Gillrie MR, Lopera-Mesa TM, Diakité SA, Arie T, Krause MA, Guindo A, Tubman A, Fujioka H, Diallo DA, Doumbo OK, Ho M, Wellems TE, Fairhurst RM. Impaired cytoadherence of Plasmodium falciparum-infected erythrocytes containing sickle hemoglobin. Proceedings of the National Academy of Sciences of the United States of America. 105: 991-6. PMID 18192399 DOI: 10.1073/Pnas.0711401105  0.92
2008 Lamm ME, Emancipator SN, Robinson JK, Yamashita M, Fujioka H, Qiu J, Plaut AG. Microbial IgA protease removes IgA immune complexes from mouse glomeruli in vivo: potential therapy for IgA nephropathy. The American Journal of Pathology. 172: 31-6. PMID 18165266 DOI: 10.2353/Ajpath.2008.070131  0.92
2007 Bonilla JA, Bonilla TD, Yowell CA, Fujioka H, Dame JB. Critical roles for the digestive vacuole plasmepsins of Plasmodium falciparum in vacuolar function. Molecular Microbiology. 65: 64-75. PMID 17581121 DOI: 10.1111/J.1365-2958.2007.05768.X  0.92
2007 Sodja A, Fujioka H, Lemos FJ, Donnelly-Doman M, Jacobs-Lorena M. Induction of actin gene expression in the mosquito midgut by blood ingestion correlates with striking changes of cell shape. Journal of Insect Physiology. 53: 833-9. PMID 17537455 DOI: 10.1016/J.Jinsphys.2007.03.017  0.92
2007 Brittain NJ, Erexson C, Faucette L, Ward J, Fujioka H, Wellems TE, Fairhurst RM. Non-opsonising aggregates of IgG and complement in haemoglobin C erythrocytes. British Journal of Haematology. 136: 491-500. PMID 17156402 DOI: 10.1111/J.1365-2141.2006.06446.X  0.92
2006 Yuan J, Xiao X, McGeehan J, Dong Z, Cali I, Fujioka H, Kong Q, Kneale G, Gambetti P, Zou WQ. Insoluble aggregates and protease-resistant conformers of prion protein in uninfected human brains. The Journal of Biological Chemistry. 281: 34848-58. PMID 16987816 DOI: 10.1074/Jbc.M602238200  0.92
2006 Devenport M, Alvarenga PH, Shao L, Fujioka H, Bianconi ML, Oliveira PL, Jacobs-Lorena M. Identification of the Aedes aegypti peritrophic matrix protein AeIMUCI as a heme-binding protein. Biochemistry. 45: 9540-9. PMID 16878988 DOI: 10.1021/Bi0605991  0.92
2006 Zimmerman PA, Thomson JM, Fujioka H, Collins WE, Zborowski M. Diagnosis of malaria by magnetic deposition microscopy. The American Journal of Tropical Medicine and Hygiene. 74: 568-72. PMID 16606985 DOI: 10.4269/Ajtmh.2006.74.568  0.92
2006 Wang T, Fujioka H, Drazba JA, Sam-Yellowe TY. Rhop-3 protein conservation among Plasmodium species and induced protection against lethal P. yoelii and P. berghei challenge. Parasitology Research. 99: 238-52. PMID 16541261 DOI: 10.1007/S00436-006-0136-9  0.92
2006 Gu Y, Luo X, Basu S, Fujioka H, Singh N. Cell-specific metabolism and pathogenesis of transmembrane prion protein. Molecular and Cellular Biology. 26: 2697-715. PMID 16537913 DOI: 10.1128/Mcb.26.7.2697-2715.2006  0.92
2006 Moore LR, Fujioka H, Williams PS, Chalmers JJ, Grimberg B, Zimmerman PA, Zborowski M. Hemoglobin degradation in malaria-infected erythrocytes determined from live cell magnetophoresis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 747-9. PMID 16461330 DOI: 10.1096/Fj.05-5122Fje  0.92
2005 Furuya T, Mu J, Hayton K, Liu A, Duan J, Nkrumah L, Joy DA, Fidock DA, Fujioka H, Vaidya AB, Wellems TE, Su XZ. Disruption of a Plasmodium falciparum gene linked to male sexual development causes early arrest in gametocytogenesis. Proceedings of the National Academy of Sciences of the United States of America. 102: 16813-8. PMID 16275909 DOI: 10.1073/Pnas.0501858102  0.92
2005 Wang Q, Fujioka H, Nussenzweig V. Mutational analysis of the GPI-anchor addition sequence from the circumsporozoite protein of Plasmodium. Cellular Microbiology. 7: 1616-26. PMID 16207248 DOI: 10.1111/J.1462-5822.2005.00579.X  0.92
2005 Wang Q, Fujioka H, Nussenzweig V. Exit of Plasmodium sporozoites from oocysts is an active process that involves the circumsporozoite protein. Plos Pathogens. 1: e9. PMID 16201021 DOI: 10.1371/Journal.Ppat.0010009  0.92
2005 Cooper RA, Papakrivos J, Lane KD, Fujioka H, Lingelbach K, Wellems TE. PfCG2, a Plasmodium falciparum protein peripherally associated with the parasitophorous vacuolar membrane, is expressed in the period of maximum hemoglobin uptake and digestion by trophozoites. Molecular and Biochemical Parasitology. 144: 167-76. PMID 16183150 DOI: 10.1016/J.Molbiopara.2005.07.009  0.92
2005 Shao L, Devenport M, Fujioka H, Ghosh A, Jacobs-Lorena M. Identification and characterization of a novel peritrophic matrix protein, Ae-Aper50, and the microvillar membrane protein, AEG12, from the mosquito, Aedes aegypti. Insect Biochemistry and Molecular Biology. 35: 947-59. PMID 15978997 DOI: 10.1016/J.Ibmb.2005.03.012  0.92
2005 Fairhurst RM, Baruch DI, Brittain NJ, Ostera GR, Wallach JS, Hoang HL, Hayton K, Guindo A, Makobongo MO, Schwartz OM, Tounkara A, Doumbo OK, Diallo DA, Fujioka H, Ho M, et al. Abnormal display of PfEMP-1 on erythrocytes carrying haemoglobin C may protect against malaria. Nature. 435: 1117-21. PMID 15973412 DOI: 10.1038/Nature03631  0.92
2005 Abraham EG, Donnelly-Doman M, Fujioka H, Ghosh A, Moreira L, Jacobs-Lorena M. Driving midgut-specific expression and secretion of a foreign protein in transgenic mosquitoes with AgAper1 regulatory elements Insect Molecular Biology. 14: 271-279. PMID 15926896 DOI: 10.1111/J.1365-2583.2004.00557.X  0.92
2005 Honda K, Smith MA, Zhu X, Baus D, Merrick WC, Tartakoff AM, Hattier T, Harris PL, Siedlak SL, Fujioka H, Liu Q, Moreira PI, Miller FP, Nunomura A, Shimohama S, et al. Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. The Journal of Biological Chemistry. 280: 20978-86. PMID 15767256 DOI: 10.1074/Jbc.M500526200  0.92
2005 Devenport M, Fujioka H, Donnelly-Doman M, Shen Z, Jacobs-Lorena M. Storage and secretion of Ag-Aper14, a novel peritrophic matrix protein, and Ag-Muc1 from the mosquito Anopheles gambiae Cell and Tissue Research. 320: 175-185. PMID 15726420 DOI: 10.1007/S00441-004-1067-3  0.92
2004 Mishra RS, Basu S, Gu Y, Luo X, Zou WQ, Mishra R, Li R, Chen SG, Gambetti P, Fujioka H, Singh N. Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: implications for species barrier in prion uptake from the intestine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 11280-90. PMID 15601934 DOI: 10.1523/Jneurosci.2864-04.2004  0.92
2004 Omara-Opyene AL, Moura PA, Sulsona CR, Bonilla JA, Yowell CA, Fujioka H, Fidock DA, Dame JB. Genetic disruption of the Plasmodium falciparum digestive vacuole plasmepsins demonstrates their functional redundancy. The Journal of Biological Chemistry. 279: 54088-96. PMID 15491999 DOI: 10.1074/Jbc.M409605200  0.92
2004 Devenport M, Fujioka H, Jacobs-Lorena M. Storage and secretion of the peritrophic matrix protein Ag-Aper1 and trypsin in the midgut of Anopheles gambiae Insect Molecular Biology. 13: 349-358. PMID 15271206 DOI: 10.1111/J.0962-1075.2004.00488.X  0.92
2004 Zhu X, Wang Y, Ogawa O, Lee HG, Raina AK, Siedlak SL, Harris PL, Fujioka H, Shimohama S, Tabaton M, Atwood CS, Petersen RB, Perry G, Smith MA. Neuroprotective properties of Bcl-w in Alzheimer disease. Journal of Neurochemistry. 89: 1233-40. PMID 15147516 DOI: 10.1111/J.1471-4159.2004.02416.X  0.92
2004 Kongkasuriyachai D, Fujioka H, Kumar N. Functional analysis of Plasmodium falciparum parasitophorous vacuole membrane protein (Pfs16) during gametocytogenesis and gametogenesis by targeted gene disruption. Molecular and Biochemical Parasitology. 133: 275-85. PMID 14698439 DOI: 10.1016/J.Molbiopara.2003.10.014  0.92
2004 Srinivasan P, Abraham EG, Ghosh AK, Valenzuela J, Ribeiro JM, Dimopoulos G, Kafatos FC, Adams JH, Fujioka H, Jacobs-Lorena M. Analysis of the Plasmodium and Anopheles transcriptomes during oocyst differentiation. The Journal of Biological Chemistry. 279: 5581-7. PMID 14627711 DOI: 10.1074/Jbc.M307587200  0.92
2004 Topolska AE, Lidgett A, Truman D, Fujioka H, Coppel RL. Characterization of a membrane-associated rhoptry protein of Plasmodium falciparum. The Journal of Biological Chemistry. 279: 4648-56. PMID 14613941 DOI: 10.1074/Jbc.M307859200  0.92
2003 Waller KL, Muhle RA, Ursos LM, Horrocks P, Verdier-Pinard D, Sidhu AB, Fujioka H, Roepe PD, Fidock DA. Chloroquine resistance modulated in vitro by expression levels of the Plasmodium falciparum chloroquine resistance transporter. The Journal of Biological Chemistry. 278: 33593-601. PMID 12813054 DOI: 10.1074/Jbc.M302215200  0.92
2003 Cash AD, Aliev G, Siedlak SL, Nunomura A, Fujioka H, Zhu X, Raina AK, Vinters HV, Tabaton M, Johnson AB, Paula-Barbosa M, Avíla J, Jones PK, Castellani RJ, Smith MA, et al. Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation. The American Journal of Pathology. 162: 1623-7. PMID 12707046 DOI: 10.1016/S0002-9440(10)64296-4  0.92
2003 Ghosh A, Srinivasan P, Abraham EG, Fujioka H, Jacobs-Lorena M. Molecular strategies to study Plasmodium-mosquito interactions Trends in Parasitology. 19: 94-101. PMID 12586478 DOI: 10.1016/S1471-4922(02)00052-1  0.92
2003 Fairhurst RM, Fujioka H, Hayton K, Collins KF, Wellems TE. Aberrant development of Plasmodium falciparum in hemoglobin CC red cells: implications for the malaria protective effect of the homozygous state. Blood. 101: 3309-15. PMID 12480691 DOI: 10.1182/Blood-2002-10-3105  0.92
2003 Bergman LW, Kaiser K, Fujioka H, Coppens I, Daly TM, Fox S, Matuschewski K, Nussenzweig V, Kappe SH. Myosin A tail domain interacting protein (MTIP) localizes to the inner membrane complex of Plasmodium sporozoites. Journal of Cell Science. 116: 39-49. PMID 12456714 DOI: 10.1242/Jcs.00194  0.92
2002 Eksi S, Stump A, Fanning SL, Shenouda MI, Fujioka H, Williamson KC. Targeting and sequestration of truncated Pfs230 in an intraerythrocytic compartment during Plasmodium falciparum gametocytogenesis. Molecular Microbiology. 44: 1507-16. PMID 12067340 DOI: 10.1046/J.1365-2958.2002.02986.X  0.92
2002 Fujioka H, Aikawa M. Structure and life cycle. Chemical Immunology. 80: 1-26. PMID 12058635 DOI: 10.1159/000058837  0.92
2002 Akompong T, Kadekoppala M, Harrison T, Oksman A, Goldberg DE, Fujioka H, Samuel BU, Sullivan D, Haldar K. Trans expression of a Plasmodium falciparum histidine-rich protein II (HRPII) reveals sorting of soluble proteins in the periphery of the host erythrocyte and disrupts transport to the malarial food vacuole. The Journal of Biological Chemistry. 277: 28923-33. PMID 12023959 DOI: 10.1074/Jbc.M201968200  0.92
2002 Thathy V, Fujioka H, Gantt S, Nussenzweig R, Nussenzweig V, Ménard R. Levels of circumsporozoite protein in the Plasmodium oocyst determine sporozoite morphology. The Embo Journal. 21: 1586-96. PMID 11927543 DOI: 10.1093/Emboj/21.7.1586  0.92
2002 Cheresh P, Harrison T, Fujioka H, Haldar K. Targeting the malarial plastid via the parasitophorous vacuole. The Journal of Biological Chemistry. 277: 16265-77. PMID 11815606 DOI: 10.1074/Jbc.M109331200  0.92
2002 Cooper RA, Ferdig MT, Su XZ, Ursos LM, Mu J, Nomura T, Fujioka H, Fidock DA, Roepe PD, Wellems TE. Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum. Molecular Pharmacology. 61: 35-42. PMID 11752204 DOI: 10.1124/Mol.61.1.35  0.92
2002 Gu Y, Fujioka H, Mishra RS, Li R, Singh N. Prion peptide 106-126 modulates the aggregation of cellular prion protein and induces the synthesis of potentially neurotoxic transmembrane PrP. The Journal of Biological Chemistry. 277: 2275-86. PMID 11682469 DOI: 10.1074/Jbc.M104345200  0.92
2001 Gu Y, Jing Y, Kumar A, Sharma Y, Fujioka H, Singh N. Isolation of human neuronal cells resistant to toxicity by the prion protein peptide 106-126. Journal of Alzheimer's Disease : Jad. 3: 169-180. PMID 12214058 DOI: 10.3233/Jad-2001-3202  0.92
2001 Mehlotra RK, Fujioka H, Roepe PD, Janneh O, Ursos LM, Jacobs-Lorena V, McNamara DT, Bockarie MJ, Kazura JW, Kyle DE, Fidock DA, Zimmerman PA. Evolution of a unique Plasmodium falciparum chloroquine-resistance phenotype in association with pfcrt polymorphism in Papua New Guinea and South America. Proceedings of the National Academy of Sciences of the United States of America. 98: 12689-94. PMID 11675500 DOI: 10.1073/Pnas.221440898  0.92
2001 Nguyen TV, Fujioka H, Kang AS, Rogers WO, Fidock DA, James AA. Stage-dependent Localization of a Novel Gene Product of the Malaria Parasite, Plasmodium falciparum Journal of Biological Chemistry. 276: 26724-26731. PMID 11371568 DOI: 10.1074/Jbc.M103375200  0.92
2001 Hirai K, Aliev G, Nunomura A, Fujioka H, Russell RL, Atwood CS, Johnson AB, Kress Y, Vinters HV, Tabaton M, Shimohama S, Cash AD, Siedlak SL, Harris PL, Jones PK, et al. Mitochondrial abnormalities in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 3017-23. PMID 11312286  0.92
2001 Sam-Yellowe TY, Fujioka H, Aikawa M, Hall T, Drazba JA. A Plasmodium falciparum protein located in Maurer's clefts underneath knobs and protein localization in association with Rhop-3 and SERA in the intracellular network of infected erythrocytes. Parasitology Research. 87: 173-85. PMID 11293564 DOI: 10.1007/Pl00008572  0.92
2000 Patankar S, Fujioka H, Wirth DF. The signal sequence and C-terminal hydrophobic domain are required for localization of the sexual stage antigen Pgs28 to the surface of P. gallinaceum ookinetes Molecular and Biochemical Parasitology. 111: 425-435. PMID 11163448 DOI: 10.1016/S0166-6851(00)00340-6  0.92
2000 Blisnick T, Morales Betoulle ME, Barale JC, Uzureau P, Berry L, Desroses S, Fujioka H, Mattei D, Braun Breton C. Pfsbp1, a Maurer's cleft Plasmodium falciparum protein, is associated with the erythrocyte skeleton Molecular and Biochemical Parasitology. 111: 107-121. PMID 11087921 DOI: 10.1016/S0166-6851(00)00301-7  0.92
2000 Brennan JDG, Kent M, Dhar R, Fujioka H, Kumar N. Anopheles gambiae salivary gland proteins as putative targets for blocking transmission of malaria parasites Proceedings of the National Academy of Sciences of the United States of America. 97: 13859-13864. PMID 11087838 DOI: 10.1073/Pnas.250472597  0.92
2000 Sam-Yellowe T, Fujioka H. Rhoptry proteins of plasmodium species Journal of Protozoology Research. 10: 39-70.  0.92
2000 Sam-Yellowe T, Wang T, Fujioka H, Drazba JA, Aikawa M, Brochak WE. Sequence analysis of the Rhop-3 gene of Plasmodium berghei and P. chabaudi, reactivity of Rhop-3 protein within isolated rhoptries and binding of Rhop-3 to mouse erythrocytes Journal of Protozoology Research. 10: 71-89.  0.92
1999 Zhang K, Fujioka H, Lobo CA, Kitayaporn D, Aikawa M, Kumar N. Cloning and characterization of a new asparagine-rich protein in Plasmodium falciparum. Parasitology Research. 85: 956-63. PMID 10599917 DOI: 10.1007/S004360050666  0.92
1999 Kappe S, Bruderer T, Gantt S, Fujioka H, Nussenzweig V, Ménard R. Conservation of a gliding motility and cell invasion machinery in Apicomplexan parasites Journal of Cell Biology. 147: 937-943. PMID 10579715 DOI: 10.1083/Jcb.147.5.937  0.92
1999 Bhisutthibhan J, Philbert MA, Fujioka H, Aikawa M, Meshnick SR. The Plasmodium falciparum translationally controlled tumor protein: Subcellular localization and calcium binding European Journal of Cell Biology. 78: 665-670. PMID 10535309 DOI: 10.1016/S0171-9335(99)80052-1  0.92
1999 Zhang K, Fujioka H, Aikawa M, Kumar N. Plasmodium falciparum: Detection of a novel asparagine-rich protein on the surface of sporozoite Experimental Parasitology. 93: 1-6. PMID 10464033 DOI: 10.1006/Expr.1999.4435  0.92
1999 Kuryshev YA, Brittenham GM, Fujioka H, Kannan P, Shieh CC, Cohen SA, Brown AM. Decreased sodium and increased transient outward potassium currents in iron-loaded cardiac myocytes: Implications for the arrhythmogenesis of human siderotic heart disease Circulation. 100: 675-683. PMID 10441107 DOI: 10.1161/01.Cir.100.6.675  0.92
1999 Sam-Yellowe TY, Fujioka H, Aikawa M. Morphological analysis of isolated rhoptries from Plasmodium yoelii, P. berghei, and P. chabaudi merozoites Experimental Parasitology. 92: 275-278. PMID 10425155 DOI: 10.1006/Expr.1999.4420  0.92
1999 Lobo CA, Fujioka H, Aikawa M, Kumar N. Disruption of the Pfg27 locus by homologous recombination leads to loss of the sexual phenotype in P. falciparum. Molecular Cell. 3: 793-8. PMID 10394367 DOI: 10.1016/S1097-2765(01)80011-3  0.92
1999 Barale JC, Blisnick T, Fujioka H, Alzari PM, Aikawa M, Braun-Breton C, Langsley G. Plasmodium falciparum subtilisin-like protease 2, a merozoite candidate for the merozoite surface protein 1-42 maturase Proceedings of the National Academy of Sciences of the United States of America. 96: 6445-6450. PMID 10339607 DOI: 10.1073/Pnas.96.11.6445  0.92
1999 Joshi MB, Lin DT, Chiang PH, Goldman ND, Fujioka H, Aikawa M, Syin C. Molecular cloning and nuclear localization of a histone deacetylase homologue in Plasmodium falciparum. Molecular and Biochemical Parasitology. 99: 11-9. PMID 10215020 DOI: 10.1016/S0166-6851(98)00177-7  0.92
1999 Huang YT, Miller CJ, Wong V, Fujioka H, Nedrud JG, Lamm ME. Replication and budding of simian immunodeficiency virus in polarized epithelial cells Virology. 257: 24-34. PMID 10208917 DOI: 10.1006/Viro.1999.9637  0.92
1999 Shi YP, Hasnain SE, Sacci JB, Holloway BP, Fujioka H, Kumar N, Wohlhueter R, Hoffman SL, Collins WE, Lal AA. Immunogenicity and in vitro protective efficacy of a recombinant multistage Plasmodium falciparum candidate vaccine. Proceedings of the National Academy of Sciences of the United States of America. 96: 1615-20. PMID 9990073 DOI: 10.1073/Pnas.96.4.1615  0.92
1999 Cooper RA, Fujioka H, Baruch DI, Wellems TE. Physicochemical properties of CG2, a candidate chloroquine resistance protein from plasmodium falciparum Proceedings of the Western Pharmacology Society. 42: 129.  0.92
1998 Wellems TE, Wootton JC, Fujioka H, Su XZ, Cooper R, Baruch D, Fidock DA. P. falciparum CG2, linked to chloroquine resistance, does not resemble Na+/H+ exchangers Cell. 94: 285-286. PMID 9708730 DOI: 10.1016/S0092-8674(00)81471-3  0.92
1998 Powles MA, Liberator P, Anderson J, Karkhanis Y, Dropinski JF, Bouffard FA, Balkovec JM, Fujioka H, Aikawa M, McFadden D, Schmatz D. Efficacy of MK-991 (L-743,872), a semisynthetic pneumocandin, in murine models of Pneumocystis carinii. Antimicrobial Agents and Chemotherapy. 42: 1985-9. PMID 9687394 DOI: 10.1128/Aac.42.8.1985  0.92
1997 Templeton TJ, Fujioka H, Aikawa M, Parker KC, Kaslow DC. Plasmodium falciparum Pfs40, renamed Pf39, is localized to an intracellular membrane-bound compartment and is not sexual stage-specific. Molecular and Biochemical Parasitology. 90: 359-65. PMID 9497061 DOI: 10.1016/S0166-6851(97)00164-3  0.92
1997 Singh N, Zanusso G, Chen SG, Fujioka H, Richardson S, Gambetti P, Petersen RB. Prion protein aggregation reverted by low temperature in transfected cells carrying a prion protein gene mutation. The Journal of Biological Chemistry. 272: 28461-70. PMID 9353306 DOI: 10.1074/Jbc.272.45.28461  0.92
1996 Guinet F, Dvorak JA, Fujioka H, Keister DB, Muratova O, Kaslow DC, Aikawa M, Vaidya AB, Wellems TE. A developmental defect in Plasmodium falciparum male gametogenesis Journal of Cell Biology. 135: 269-278. PMID 8858179 DOI: 10.1083/jcb.135.1.269  0.92
1996 Yang JC, Blanton RE, King CL, Fujioka H, Aikawa M, Sam-Yellowe TY. Seroprevalence and specificity of human responses to the Plasmodium falciparum rhoptry protein Rhop-3 determined by using a C-terminal recombinant protein. Infection and Immunity. 64: 3584-91. PMID 8751903 DOI: 10.1128/Iai.64.9.3584-3591.1996  0.92
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