Stephen J. Hill, BSc, PhD - Publications

Affiliations: 
Biomedical Sciences University of Nottingham, Nottingham, England, United Kingdom 

208 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Bouzo-Lorenzo M, Stoddart LA, Xia L, IJzerman AP, Heitman LH, Briddon SJ, Hill SJ. A live cell NanoBRET binding assay allows the study of ligand-binding kinetics to the adenosine A receptor. Purinergic Signalling. PMID 30919204 DOI: 10.1007/s11302-019-09650-9  0.44
2018 Alcobia DC, Ziegler AI, Kondrashov A, Comeo E, Mistry S, Kellam B, Chang A, Woolard J, Hill SJ, Sloan EK. Visualizing Ligand Binding to a GPCR In Vivo Using NanoBRET. Iscience. 6: 280-288. PMID 30240618 DOI: 10.1016/j.isci.2018.08.006  0.44
2018 Conroy S, Kindon ND, Glenn J, Stoddart LA, Lewis RJ, Hill SJ, Kellam B, Stocks MJ. Correction to Synthesis and Evaluation of the First Fluorescent Antagonists of the Human P2Y Receptor Based on AR-C118925. Journal of Medicinal Chemistry. PMID 29688707 DOI: 10.1021/acs.jmedchem.8b00606  0.44
2018 Conroy S, Kindon ND, Glenn J, Stoddart LA, Lewis RJ, Hill SJ, Kellam B, Stocks MJ. Synthesis and Evaluation of the first Fluorescent Antagonists of the Human P2YReceptor based on AR-C118925. Journal of Medicinal Chemistry. PMID 29558126 DOI: 10.1021/acs.jmedchem.8b00139  0.44
2018 Stoddart LA, Vernall AJ, Bouzo-Lorenzo M, Bosma R, Kooistra AJ, de Graaf C, Vischer HF, Leurs R, Briddon SJ, Kellam B, Hill SJ. Development of novel fluorescent histamine H1-receptor antagonists to study ligand-binding kinetics in living cells. Scientific Reports. 8: 1572. PMID 29371669 DOI: 10.1038/s41598-018-19714-2  0.44
2017 Arruda MA, Stoddart LA, Gherbi K, Briddon SJ, Kellam B, Hill SJ. A Non-imaging High Throughput Approach to Chemical Library Screening at the Unmodified Adenosine-A3 Receptor in Living Cells. Frontiers in Pharmacology. 8: 908. PMID 29321740 DOI: 10.3389/fphar.2017.00908  0.44
2017 Briddon SJ, Kilpatrick LE, Hill SJ. Studying GPCR Pharmacology in Membrane Microdomains: Fluorescence Correlation Spectroscopy Comes of Age. Trends in Pharmacological Sciences. PMID 29277246 DOI: 10.1016/j.tips.2017.11.004  0.44
2017 Baker JG, Gardiner SM, Woolard J, Fromont C, Jadhav GP, Mistry SN, Thompson KS, Kellam B, Hill SJ, Fischer PM. Novel selective β1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28400472 DOI: 10.1096/fj.201601305R  0.44
2017 Kilpatrick LE, Friedman-Ohana R, Alcobia DC, Riching K, Peach CJ, Wheal AJ, Briddon SJ, Robers MB, Zimmerman K, Machleidt T, Wood KV, Woolard J, Hill SJ. Real-time analysis of the binding of fluorescent VEGF165a to VEGFR2 in living cells: Effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor complexes. Biochemical Pharmacology. PMID 28392095 DOI: 10.1016/j.bcp.2017.04.006  0.44
2015 Ranganathan A, Stoddart LA, Hill SJ, Carlsson J. Fragment-based discovery of subtype selective adenosine receptor ligands from homology models. Journal of Medicinal Chemistry. PMID 26592528 DOI: 10.1021/acs.jmedchem.5b01120  1
2015 Stoddart LA, White CW, Nguyen K, Hill SJ, Pfleger KD. Fluorescence- and bioluminescence-based approaches to study GPCR ligand binding. British Journal of Pharmacology. PMID 26317175 DOI: 10.1111/bph.13316  1
2015 Hoffmann C, Castro M, Rinken A, Leurs R, Hill SJ, Vischer HF. Ligand Residence Time at G-protein-Coupled Receptors-Why We Should Take Our Time To Study It. Molecular Pharmacology. 88: 552-60. PMID 26152198 DOI: 10.1124/mol.115.099671  1
2015 Stoddart LA, Kilpatrick LE, Briddon SJ, Hill SJ. Probing the pharmacology of G protein-coupled receptors with fluorescent ligands. Neuropharmacology. 98: 48-57. PMID 25979488 DOI: 10.1016/j.neuropharm.2015.04.033  0.44
2015 van Unen J, Woolard J, Rinken A, Hoffmann C, Hill SJ, Goedhart J, Bruchas MR, Bouvier M, Adjobo-Hermans MJ. A Perspective on Studying G-Protein-Coupled Receptor Signaling with Resonance Energy Transfer Biosensors in Living Organisms. Molecular Pharmacology. 88: 589-95. PMID 25972446 DOI: 10.1124/mol.115.098897  1
2015 Stoddart LA, Vernall AJ, Briddon SJ, Kellam B, Hill SJ. Direct visualisation of internalization of the adenosine A3 receptor and localization with arrestin3 using a fluorescent agonist. Neuropharmacology. 98: 68-77. PMID 25937210 DOI: 10.1016/j.neuropharm.2015.04.013  1
2015 Gherbi K, May LT, Baker JG, Briddon SJ, Hill SJ. Negative cooperativity across β1-adrenoceptor homodimers provides insights into the nature of the secondary low-affinity CGP 12177 β1-adrenoceptor binding conformation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2859-71. PMID 25837585 DOI: 10.1096/fj.14-265199  1
2015 Carter JJ, Wheal AJ, Hill SJ, Woolard J. Effects of receptor tyrosine kinase inhibitors on VEGF165 a- and VEGF165 b-stimulated gene transcription in HEK-293 cells expressing human VEGFR2. British Journal of Pharmacology. 172: 3141-50. PMID 25684635 DOI: 10.1111/bph.13116  1
2015 Baker JG, Proudman RG, Hill SJ. Salmeterol's extreme β2 selectivity is due to residues in both extracellular loops and transmembrane domains. Molecular Pharmacology. 87: 103-20. PMID 25324048 DOI: 10.1124/mol.114.095364  1
2015 Stoddart LA, Kilpatrick LE, Briddon SJ, Hill SJ. Probing the pharmacology of G protein-coupled receptors with fluorescent ligands Neuropharmacology. DOI: 10.1016/j.neuropharm.2015.04.033  1
2014 Gherbi K, Briddon SJ, Hill SJ. Detection of the secondary, low-affinity β1 -adrenoceptor site in living cells using the fluorescent CGP 12177 derivative BODIPY-TMR-CGP. British Journal of Pharmacology. 171: 5431-45. PMID 25052258 DOI: 10.1111/bph.12858  1
2014 Corriden R, Kilpatrick LE, Kellam B, Briddon SJ, Hill SJ. Kinetic analysis of antagonist-occupied adenosine-A3 receptors within membrane microdomains of individual cells provides evidence of receptor dimerization and allosterism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4211-22. PMID 24970394 DOI: 10.1096/fj.13-247270  1
2014 Stoddart LA, Kellam B, Briddon SJ, Hill SJ. Effect of a toggle switch mutation in TM6 of the human adenosine A₃ receptor on Gi protein-dependent signalling and Gi-independent receptor internalization. British Journal of Pharmacology. 171: 3827-44. PMID 24750014 DOI: 10.1111/bph.12739  1
2014 Jaeger WC, Armstrong SP, Hill SJ, Pfleger KD. Biophysical Detection of Diversity and Bias in GPCR Function. Frontiers in Endocrinology. 5: 26. PMID 24634666 DOI: 10.3389/fendo.2014.00026  1
2014 Baker JG, Proudman RG, Hill SJ. Identification of key residues in transmembrane 4 responsible for the secondary, low-affinity conformation of the human β1-adrenoceptor. Molecular Pharmacology. 85: 811-29. PMID 24608857 DOI: 10.1124/mol.114.091587  1
2014 Hutchings CJ, Cseke G, Osborne G, Woolard J, Zhukov A, Koglin M, Jazayeri A, Pandya-Pathak J, Langmead CJ, Hill SJ, Weir M, Marshall FH. Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment. Mabs. 6: 246-61. PMID 24253107 DOI: 10.4161/mabs.27226  1
2014 Hill SJ, May LT, Kellam B, Woolard J. Allosteric interactions at adenosine A(1) and A(3) receptors: new insights into the role of small molecules and receptor dimerization. British Journal of Pharmacology. 171: 1102-13. PMID 24024783 DOI: 10.1111/bph.12345  1
2014 Vernall AJ, Hill SJ, Kellam B. The evolving small-molecule fluorescent-conjugate toolbox for Class A GPCRs. British Journal of Pharmacology. 171: 1073-84. PMID 23734587 DOI: 10.1111/bph.12265  1
2013 Baker JG, Proudman RG, Hill SJ. Impact of polymorphic variants on the molecular pharmacology of the two-agonist conformations of the human β1-adrenoceptor. Plos One. 8: e77582. PMID 24250787 DOI: 10.1371/journal.pone.0077582  1
2013 Stoddart LA, Briddon SJ, Hill SJ. Fluorescent ligands for G protein-coupled receptors: illuminating receptor-ligand interactions for drug discovery. Future Medicinal Chemistry. 5: 1367-9. PMID 23919546 DOI: 10.4155/fmc.13.110  1
2013 Vernall AJ, Stoddart LA, Briddon SJ, Ng HW, Laughton CA, Doughty SW, Hill SJ, Kellam B. Conversion of a non-selective adenosine receptor antagonist into A3-selective high affinity fluorescent probes using peptide-based linkers. Organic & Biomolecular Chemistry. 11: 5673-82. PMID 23881285 DOI: 10.1039/c3ob41221k  1
2013 Corriden R, Self T, Akong-Moore K, Nizet V, Kellam B, Briddon SJ, Hill SJ. Adenosine-A3 receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes. Embo Reports. 14: 726-32. PMID 23817552 DOI: 10.1038/embor.2013.89  1
2013 Mistry SN, Baker JG, Fischer PM, Hill SJ, Gardiner SM, Kellam B. Synthesis and in vitro and in vivo characterization of highly β1-selective β-adrenoceptor partial agonists. Journal of Medicinal Chemistry. 56: 3852-65. PMID 23614528 DOI: 10.1021/jm400348g  1
2012 Stoddart LA, Vernall AJ, Denman JL, Briddon SJ, Kellam B, Hill SJ. Fragment screening at adenosine-A(3) receptors in living cells using a fluorescence-based binding assay. Chemistry & Biology. 19: 1105-15. PMID 22999879 DOI: 10.1016/j.chembiol.2012.07.014  1
2012 Ayling LJ, Briddon SJ, Halls ML, Hammond GR, Vaca L, Pacheco J, Hill SJ, Cooper DM. Adenylyl cyclase AC8 directly controls its micro-environment by recruiting the actin cytoskeleton in a cholesterol-rich milieu. Journal of Cell Science. 125: 869-86. PMID 22399809 DOI: 10.1242/jcs.091090  1
2012 Vernall AJ, Stoddart LA, Briddon SJ, Hill SJ, Kellam B. Highly potent and selective fluorescent antagonists of the human adenosine A₃ receptor based on the 1,2,4-triazolo[4,3-a]quinoxalin-1-one scaffold. Journal of Medicinal Chemistry. 55: 1771-82. PMID 22277057 DOI: 10.1021/jm201722y  1
2012 Rose RH, Briddon SJ, Hill SJ. A novel fluorescent histamine H(1) receptor antagonist demonstrates the advantage of using fluorescence correlation spectroscopy to study the binding of lipophilic ligands. British Journal of Pharmacology. 165: 1789-800. PMID 21880035 DOI: 10.1111/j.1476-5381.2011.01640.x  1
2012 Dale CL, Hill SJ, Kellam B. New potent, short-linker BODIPY-630/650™ labelled fluorescent adenosine receptor agonists Medchemcomm. 3: 333-338. DOI: 10.1039/c2md00247g  1
2011 Baker JG, Adams LA, Salchow K, Mistry SN, Middleton RJ, Hill SJ, Kellam B. Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors. Journal of Medicinal Chemistry. 54: 6874-87. PMID 21870877 DOI: 10.1021/jm2008562  1
2011 Baker JG, Kemp P, March J, Fretwell L, Hill SJ, Gardiner SM. Predicting in vivo cardiovascular properties of β-blockers from cellular assays: a quantitative comparison of cellular and cardiovascular pharmacological responses. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 4486-97. PMID 21865315 DOI: 10.1096/fj.11-192435  1
2011 May LT, Bridge LJ, Stoddart LA, Briddon SJ, Hill SJ. Allosteric interactions across native adenosine-A3 receptor homodimers: quantification using single-cell ligand-binding kinetics. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 3465-76. PMID 21715680 DOI: 10.1096/fj.11-186296  1
2011 Briddon SJ, Kellam B, Hill SJ. Design and use of fluorescent ligands to study ligand-receptor interactions in single living cells. Methods in Molecular Biology (Clifton, N.J.). 746: 211-36. PMID 21607859 DOI: 10.1007/978-1-61779-126-0_11  1
2011 Baker JG, Hill SJ, Summers RJ. Evolution of β-blockers: from anti-anginal drugs to ligand-directed signalling. Trends in Pharmacological Sciences. 32: 227-34. PMID 21429598 DOI: 10.1016/j.tips.2011.02.010  1
2011 Alcock J, Warren AY, Goodson YJ, Hill SJ, Khan RN, Lymn JS. Inhibition of tissue transglutaminase 2 attenuates contractility of pregnant human myometrium. Biology of Reproduction. 84: 646-53. PMID 21123816 DOI: 10.1095/biolreprod.110.085506  1
2010 Hill SJ, Williams C, May LT. Insights into GPCR pharmacology from the measurement of changes in intracellular cyclic AMP; advantages and pitfalls of differing methodologies. British Journal of Pharmacology. 161: 1266-75. PMID 21049583 DOI: 10.1111/j.1476-5381.2010.00779.x  1
2010 May LT, Self TJ, Briddon SJ, Hill SJ. The effect of allosteric modulators on the kinetics of agonist-G protein-coupled receptor interactions in single living cells. Molecular Pharmacology. 78: 511-23. PMID 20571079 DOI: 10.1124/mol.110.064493  1
2010 Kilpatrick LE, Briddon SJ, Hill SJ, Holliday ND. Quantitative analysis of neuropeptide Y receptor association with beta-arrestin2 measured by bimolecular fluorescence complementation. British Journal of Pharmacology. 160: 892-906. PMID 20438572 DOI: 10.1111/j.1476-5381.2010.00676.x  1
2010 Baker JG, Middleton R, Adams L, May LT, Briddon SJ, Kellam B, Hill SJ. Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A1 receptor ligands. British Journal of Pharmacology. 159: 772-86. PMID 20105183 DOI: 10.1111/j.1476-5381.2009.00488.x  1
2010 May LT, Briddon SJ, Hill SJ. Antagonist selective modulation of adenosine A1 and A3 receptor pharmacology by the food dye Brilliant Black BN: evidence for allosteric interactions. Molecular Pharmacology. 77: 678-86. PMID 20086038 DOI: 10.1124/mol.109.063065  1
2010 Bridge LJ, King JR, Hill SJ, Owen MR. Mathematical modelling of signalling in a two-ligand G-protein coupled receptor system: agonist-antagonist competition. Mathematical Biosciences. 223: 115-32. PMID 19932126 DOI: 10.1016/j.mbs.2009.11.005  1
2010 Woodroffe PJ, Bridge LJ, King JR, Chen CY, Hill SJ. Modelling of the activation of G-protein coupled receptors: drug free constitutive receptor activity. Journal of Mathematical Biology. 60: 313-46. PMID 19347339 DOI: 10.1007/s00285-009-0268-5  1
2010 Briddon SJ, Hern JA, Hill SJ. Use of Fluorescence Correlation Spectroscopy to Study the Diffusion of G Protein-coupled Receptors G Protein-Coupled Receptors: Essential Methods. 169-195. DOI: 10.1002/9780470749210.ch9  1
2010 May LT, Holliday ND, Hill SJ. The Evolving Pharmacology of GPCRs Gpcr Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions. 27-60. DOI: 10.1002/9780470627327.ch2  1
2009 Williams C, Hill SJ. GPCR signaling: understanding the pathway to successful drug discovery. Methods in Molecular Biology (Clifton, N.J.). 552: 39-50. PMID 19513640 DOI: 10.1007/978-1-60327-317-6_3  1
2009 Woodroffe PJ, Bridge LJ, King JR, Hill SJ. Modelling the activation of G-protein coupled receptors by a single drug. Mathematical Biosciences. 219: 32-55. PMID 19249318 DOI: 10.1016/j.mbs.2009.02.003  1
2008 Briddon SJ, Gandía J, Amaral OB, Ferré S, Lluís C, Franco R, Hill SJ, Ciruela F. Plasma membrane diffusion of G protein-coupled receptor oligomers. Biochimica Et Biophysica Acta. 1783: 2262-8. PMID 18691614 DOI: 10.1016/j.bbamcr.2008.07.006  1
2008 Baker JG, Proudman RG, Hawley NC, Fischer PM, Hill SJ. Role of key transmembrane residues in agonist and antagonist actions at the two conformations of the human beta1-adrenoceptor. Molecular Pharmacology. 74: 1246-60. PMID 18687809 DOI: 10.1124/mol.108.048371  1
2008 Cordell RL, Hill SJ, Ortori CA, Barrett DA. Quantitative profiling of nucleotides and related phosphate-containing metabolites in cultured mammalian cells by liquid chromatography tandem electrospray mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 871: 115-24. PMID 18650133 DOI: 10.1016/j.jchromb.2008.07.005  1
2008 May LT, Hill SJ. ERK phosphorylation: spatial and temporal regulation by G protein-coupled receptors. The International Journal of Biochemistry & Cell Biology. 40: 2013-7. PMID 18502166 DOI: 10.1016/j.biocel.2008.04.001  1
2008 Longden J, Cooke EL, Hill SJ. Effect of CCR5 receptor antagonists on endocytosis of the human CCR5 receptor in CHO-K1 cells. British Journal of Pharmacology. 153: 1513-27. PMID 18223665 DOI: 10.1038/sj.bjp.0707691  1
2008 Cordeaux Y, Briddon SJ, Alexander SP, Kellam B, Hill SJ. Agonist-occupied A3 adenosine receptors exist within heterogeneous complexes in membrane microdomains of individual living cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 850-60. PMID 17959910 DOI: 10.1096/fj.07-8180com  1
2007 Briddon SJ, Hill SJ. Pharmacology under the microscope: the use of fluorescence correlation spectroscopy to determine the properties of ligand-receptor complexes. Trends in Pharmacological Sciences. 28: 637-45. PMID 18001848 DOI: 10.1016/j.tips.2007.09.008  1
2007 Anderson D, Self T, Mellor IR, Goh G, Hill SJ, Denning C. Transgenic enrichment of cardiomyocytes from human embryonic stem cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 2027-36. PMID 17895862 DOI: 10.1038/sj.mt.6300303  1
2007 Baker JG, Hill SJ. Multiple GPCR conformations and signalling pathways: implications for antagonist affinity estimates. Trends in Pharmacological Sciences. 28: 374-81. PMID 17629959 DOI: 10.1016/j.tips.2007.06.011  1
2007 Middleton RJ, Briddon SJ, Cordeaux Y, Yates AS, Dale CL, George MW, Baker JG, Hill SJ, Kellam B. New fluorescent adenosine A1-receptor agonists that allow quantification of ligand-receptor interactions in microdomains of single living cells. Journal of Medicinal Chemistry. 50: 782-93. PMID 17249651 DOI: 10.1021/jm061279i  1
2007 Baker JG, Hill SJ. A comparison of the antagonist affinities for the Gi- and Gs-coupled states of the human adenosine A1-receptor. The Journal of Pharmacology and Experimental Therapeutics. 320: 218-28. PMID 17018691 DOI: 10.1124/jpet.106.113589  1
2006 Hill SJ. G-protein-coupled receptors: past, present and future. British Journal of Pharmacology. 147: S27-37. PMID 16402114 DOI: 10.1038/sj.bjp.0706455  1
2005 Self TJ, Oakley SM, Hill SJ. Clathrin-independent internalization of the human histamine H1-receptor in CHO-K1 cells. British Journal of Pharmacology. 146: 612-24. PMID 16086035 DOI: 10.1038/sj.bjp.0706337  1
2005 Carter AA, Hill SJ. Characterization of isoprenaline- and salmeterol-stimulated interactions between beta2-adrenoceptors and beta-arrestin 2 using beta-galactosidase complementation in C2C12 cells. The Journal of Pharmacology and Experimental Therapeutics. 315: 839-48. PMID 16051698 DOI: 10.1124/jpet.105.088914  1
2005 Liu B, Hill SJ, Khan RN. Oxytocin inhibits T-type calcium current of human decidual stromal cells. The Journal of Clinical Endocrinology and Metabolism. 90: 4191-7. PMID 15855255 DOI: 10.1210/jc.2005-0480  1
2005 Myatt A, Hill SJ. Trypsin stimulates the phosphorylation of p42,44 mitogen-activated protein kinases via the proteinase-activated receptor-2 and protein kinase C epsilon in human cultured prostate stromal cells. The Prostate. 64: 175-85. PMID 15678497 DOI: 10.1002/pros.20205  1
2004 Cordeaux Y, Ijzerman AP, Hill SJ. Coupling of the human A1 adenosine receptor to different heterotrimeric G proteins: evidence for agonist-specific G protein activation. British Journal of Pharmacology. 143: 705-14. PMID 15302686 DOI: 10.1038/sj.bjp.0705925  1
2004 Briddon SJ, Middleton RJ, Cordeaux Y, Flavin FM, Weinstein JA, George MW, Kellam B, Hill SJ. Quantitative analysis of the formation and diffusion of A1-adenosine receptor-antagonist complexes in single living cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 4673-8. PMID 15070776 DOI: 10.1073/pnas.0400420101  1
2004 Baker JG, Hall IP, Hill SJ. Temporal characteristics of cAMP response element-mediated gene transcription: requirement for sustained cAMP production. Molecular Pharmacology. 65: 986-98. PMID 15044629 DOI: 10.1124/mol.65.4.986  1
2004 Briddon SJ, Middleton RJ, Yates AS, George MW, Kellam B, Hill SJ. Application of fluorescence correlation spectroscopy to the measurement of agonist binding to a G-protein coupled receptor at the single cell level. Faraday Discussions. 126: 197-207; discussion . PMID 14992407  1
2003 Baker JG, Hall IP, Hill SJ. Agonist and inverse agonist actions of beta-blockers at the human beta 2-adrenoceptor provide evidence for agonist-directed signaling. Molecular Pharmacology. 64: 1357-69. PMID 14645666 DOI: 10.1124/mol.64.6.1357  1
2003 Baker JG, Hall IP, Hill SJ. Influence of agonist efficacy and receptor phosphorylation on antagonist affinity measurements: differences between second messenger and reporter gene responses. Molecular Pharmacology. 64: 679-88. PMID 12920204 DOI: 10.1124/mol.64.3.679  1
2003 Chen CY, Cordeaux Y, Hill SJ, King JR. Modelling of signalling via G-protein coupled receptors: pathway-dependent agonist potency and efficacy. Bulletin of Mathematical Biology. 65: 933-58. PMID 12909256 DOI: 10.1016/S0092-8240(03)00055-7  1
2003 Hill KJ, Webber AC, Hill SJ. A role of protein kinase C mu in signalling from the human adenosine A1 receptor to the nucleus. British Journal of Pharmacology. 139: 721-32. PMID 12812995 DOI: 10.1038/sj.bjp.0705294  1
2003 Baker JG, Hall IP, Hill SJ. Pharmacology and direct visualisation of BODIPY-TMR-CGP: a long-acting fluorescent beta2-adrenoceptor agonist. British Journal of Pharmacology. 139: 232-42. PMID 12770928 DOI: 10.1038/sj.bjp.0705287  1
2003 Baker JG, Hall IP, Hill SJ. Agonist actions of "beta-blockers" provide evidence for two agonist activation sites or conformations of the human beta1-adrenoceptor. Molecular Pharmacology. 63: 1312-21. PMID 12761341 DOI: 10.1124/mol.63.6.1312  1
2003 Hill SJ, Baker JG. The ups and downs of Gs- to Gi-protein switching. British Journal of Pharmacology. 138: 1188-9. PMID 12711616 DOI: 10.1038/sj.bjp.0705192  1
2003 Liu B, Arulkumaran S, Hill SJ, Khan RN. Comparison of potassium currents in human decidua before and after the onset of labor. Biology of Reproduction. 68: 2281-8. PMID 12606323 DOI: 10.1095/biolreprod.102.011890  1
2002 Burton CL, Chhabra SR, Swift S, Baldwin TJ, Withers H, Hill SJ, Williams P. The growth response of Escherichia coli to neurotransmitters and related catecholamine drugs requires a functional enterobactin biosynthesis and uptake system. Infection and Immunity. 70: 5913-23. PMID 12379665 DOI: 10.1128/IAI.70.11.5913-5923.2002  1
2002 Baker JG, Hall IP, Hill SJ. Pharmacological characterization of CGP 12177 at the human beta(2)-adrenoceptor. British Journal of Pharmacology. 137: 400-8. PMID 12237261 DOI: 10.1038/sj.bjp.0704855  1
2002 Cordeaux Y, Hill SJ. Mechanisms of cross-talk between G-protein-coupled receptors. Neuro-Signals. 11: 45-57. PMID 11943882 DOI: 10.1159/000057321  1
2001 Hill SJ, Baker JG, Rees S. Reporter-gene systems for the study of G-protein-coupled receptors. Current Opinion in Pharmacology. 1: 526-32. PMID 11764780 DOI: 10.1016/S1471-4892(01)00091-1  1
2001 Middleton A, Nury D, Willington SJ, Latif L, Hill SJ, Middleton B. Modulation by cellular cholesterol of gene transcription via the cyclic AMP response element. Biochemical Pharmacology. 62: 171-81. PMID 11389875 DOI: 10.1016/S0006-2952(01)00641-4  1
2001 Megson AC, Walker EM, Hill SJ. Role of protein kinase Calpha in signaling from the histamine H(1) receptor to the nucleus. Molecular Pharmacology. 59: 1012-21. PMID 11306682  1
2000 Cordeaux Y, Briddon SJ, Megson AE, McDonnell J, Dickenson JM, Hill SJ. Influence of receptor number on functional responses elicited by agonists acting at the human adenosine A(1) receptor: evidence for signaling pathway-dependent changes in agonist potency and relative intrinsic activity. Molecular Pharmacology. 58: 1075-84. PMID 11040056  1
2000 Hopkinson HE, Latif ML, Hill SJ. Non-competitive antagonism of beta(2)-agonist-mediated cyclic AMP accumulation by ICI 118551 in BC3H1 cells endogenously expressing constitutively active beta(2)-adrenoceptors. British Journal of Pharmacology. 131: 124-30. PMID 10960078 DOI: 10.1038/sj.bjp.0703535  1
1999 Haynes JM, Selbie LA, Hill SJ. Gi-Protein alpha-subunit mRNA antisense oligonucleotide inhibition of Gi-coupled receptor contractile activity in the epididymis of the guinea-pig. British Journal of Pharmacology. 127: 85-90. PMID 10369459 DOI: 10.1038/sj.bjp.0702515  1
1998 Dickenson JM, Hill SJ. Potentiation of adenosine A1 receptor-mediated inositol phospholipid hydrolysis by tyrosine kinase inhibitors in CHO cells. British Journal of Pharmacology. 125: 1049-57. PMID 9846644 DOI: 10.1038/sj.bjp.0702170  1
1998 McDonnell J, Latif ML, Rees ES, Bevan NJ, Hill SJ. Influence of receptor number on the stimulation by salmeterol of gene transcription in CHO-K1 cells transfected with the human beta2-adrenoceptor. British Journal of Pharmacology. 125: 717-26. PMID 9831907 DOI: 10.1038/sj.bjp.0702139  1
1998 Walker EM, Bispham JR, Hill SJ. Nonselective effects of the putative phospholipase C inhibitor, U73122, on adenosine A1 receptor-mediated signal transduction events in Chinese hamster ovary cells. Biochemical Pharmacology. 56: 1455-62. PMID 9827577 DOI: 10.1016/S0006-2952(98)00256-1  1
1998 Haynes JM, Alexander SP, Hill SJ. A1 and A2 adenosine receptor modulation of contractility in the cauda epididymis of the guinea-pig. British Journal of Pharmacology. 125: 570-6. PMID 9806342 DOI: 10.1038/sj.bjp.0702095  1
1998 Dickenson JM, Hill SJ. Involvement of G-protein betagamma subunits in coupling the adenosine A1 receptor to phospholipase C in transfected CHO cells. European Journal of Pharmacology. 355: 85-93. PMID 9754942 DOI: 10.1016/S0014-2999(98)00468-3  1
1998 Dickenson JM, Blank JL, Hill SJ. Human adenosine A1 receptor and P2Y2-purinoceptor-mediated activation of the mitogen-activated protein kinase cascade in transfected CHO cells. British Journal of Pharmacology. 124: 1491-9. PMID 9723963 DOI: 10.1038/sj.bjp.0701977  1
1998 Haynes JM, Alexander SP, Hill SJ. A1 adenosine receptor modulation of electrically-evoked contractions in the bisected vas deferens and cauda epididymis of the guinea-pig. British Journal of Pharmacology. 124: 964-70. PMID 9692782 DOI: 10.1038/sj.bjp.0701909  1
1998 Dickenson JM, Hill SJ. Human 5-HT1B receptor stimulated inositol phospholipid hydrolysis in CHO cells: synergy with Gq-coupled receptors. European Journal of Pharmacology. 348: 279-85. PMID 9652344 DOI: 10.1016/S0014-2999(98)00148-4  1
1998 Selbie LA, Hill SJ. G protein-coupled-receptor cross-talk: the fine-tuning of multiple receptor-signalling pathways. Trends in Pharmacological Sciences. 19: 87-93. PMID 9584624 DOI: 10.1016/S0165-6147(97)01166-8  1
1997 Haynes JM, Hill SJ, Selbie LA. Neuropeptide Y (NPY) and peptide YY (PYY) effects in the epididymis of the guinea-pig: evidence of a pre-junctional PYY-selective receptor. British Journal of Pharmacology. 122: 1530-6. PMID 9421306 DOI: 10.1038/sj.bjp.0701544  1
1997 Haynes JM, Hill SJ. Beta-adrenoceptor-mediated inhibition of alpha 1-adrenoceptor-mediated and field stimulation-induced contractile responses in the prostate of the guinea pig. British Journal of Pharmacology. 122: 1067-74. PMID 9401771 DOI: 10.1038/sj.bjp.0701494  1
1997 Marsh KA, Draper LM, Rubin PC, Hill SJ. Receptor-stimulated phospholipase C activity in human umbilical artery cultured endothelial cells grown in a low oxygen environment. Biochemical Pharmacology. 54: 1351-9. PMID 9393678 DOI: 10.1016/S0006-2952(97)00324-9  1
1997 Selbie LA, King NV, Dickenson JM, Hill SJ. Role of G-protein beta gamma subunits in the augmentation of P2Y2 (P2U)receptor-stimulated responses by neuropeptide Y Y1 Gi/o-coupled receptors. The Biochemical Journal. 328: 153-8. PMID 9359846  1
1997 Cooper J, Hill SJ, Alexander SP. An endogenous A2B adenosine receptor coupled to cyclic AMP generation in human embryonic kidney (HEK 293) cells. British Journal of Pharmacology. 122: 546-50. PMID 9351513 DOI: 10.1038/sj.bjp.0701401  1
1997 Hill SJ, Ganellin CR, Timmerman H, Schwartz JC, Shankley NP, Young JM, Schunack W, Levi R, Haas HL. International Union of Pharmacology. XIII. Classification of histamine receptors. Pharmacological Reviews. 49: 253-78. PMID 9311023  1
1997 Dickenson JM, Hill SJ. Transfected adenosine A1 receptor-mediated modulation of thrombin-stimulated phospholipase C and phospholipase A2 activity in CHO cells. European Journal of Pharmacology. 321: 77-86. PMID 9083789 DOI: 10.1016/S0014-2999(96)00917-X  1
1997 Chua CB, Harriss DR, Marsh KA, Hill SJ. Detrusor instability - Is it due to defective receptor desensitization? British Journal of Urology. 79: 58-59.  1
1996 Alexander SP, Cooper J, Shine J, Hill SJ. Characterization of the human brain putative A2B adenosine receptor expressed in Chinese hamster ovary (CHO.A2B4) cells. British Journal of Pharmacology. 119: 1286-90. PMID 8937736  1
1996 Haynes JM, Hill SJ. Alpha-adrenoceptor mediated responses of the cauda epididymis of the guinea-pig. British Journal of Pharmacology. 119: 1203-10. PMID 8937724  1
1996 Clark EA, Hill SJ. Sensitivity of histamine H3 receptor agonist-stimulated [35S]GTP gamma[S] binding to pertussis toxin. European Journal of Pharmacology. 296: 223-5. PMID 8838460 DOI: 10.1016/0014-2999(95)00800-4  1
1996 Peakman MC, Hill SJ. Adenosine A1 receptor-mediated inhibition of cyclic AMP accumulation in type-2 but not type-1 rat astrocytes. European Journal of Pharmacology. 306: 281-9. PMID 8813642 DOI: 10.1016/0014-2999(96)00202-6  1
1996 Dickenson JM, Hill SJ. Synergistic interactions between human transfected adenosine A1 receptors and endogenous cholecystokinin receptors in CHO cells. European Journal of Pharmacology. 302: 141-51. PMID 8791002 DOI: 10.1016/0014-2999(96)00039-8  1
1996 Marsh KA, Harrisss DR, Hill SJ. Desensitization of muscarinic receptor-coupled inositol phospholipid hydrolysis in human detrusor cultured smooth cells. The Journal of Urology. 155: 1439-43. PMID 8632607 DOI: 10.1016/S0022-5347(01)66303-1  1
1995 Dickenson JM, Hill SJ. Coupling of an endogenous 5-HT1B-like receptor to increases in intracellular calcium through a pertussis toxin-sensitive mechanism in CHO-K1 cells. British Journal of Pharmacology. 116: 2889-96. PMID 8680721  1
1995 Megson AC, Dickenson JM, Townsend-Nicholson A, Hill SJ. Synergy between the inositol phosphate responses to transfected human adenosine A1-receptors and constitutive P2-purinoceptors in CHO-K1 cells. British Journal of Pharmacology. 115: 1415-24. PMID 8564200  0.36
1995 Peakman MC, Hill SJ. Adenosine A1 receptor-mediated changes in basal and histamine-stimulated levels of intracellular calcium in primary rat astrocytes. British Journal of Pharmacology. 115: 801-10. PMID 8548180  1
1995 Cooper JA, Hill SJ, Alexander SP, Rubin PC, Horn EH. Adenosine receptor-induced cyclic AMP generation and inhibition of 5-hydroxytryptamine release in human platelets. British Journal of Clinical Pharmacology. 40: 43-50. PMID 8527267  1
1995 Clark EA, Hill SJ. Differential effect of sodium ions and guanine nucleotides on the binding of thioperamide and clobenpropit to histamine H3-receptors in rat cerebral cortical membranes. British Journal of Pharmacology. 114: 357-62. PMID 7881735  1
1995 Dickenson JM, Camps M, Gierschik P, Hill SJ. Activation of phospholipase C by G-protein beta gamma subunits in DDT1MF-2 cells. European Journal of Pharmacology. 288: 393-8. PMID 7774686  0.36
1995 Dickenson JM, Hill SJ. Activation of phospholipase C by G-protein beta gamma subunits in DDT1MF-2 cells. Biochemical Society Transactions. 23: 17S. PMID 7758722  1
1995 Hawley J, Rubin PC, Hill SJ. Distribution of receptors mediating phosphoinositide hydrolysis in cultured human umbilical artery smooth muscle and endothelial cells. Biochemical Pharmacology. 49: 1005-11. PMID 7741756 DOI: 10.1016/0006-2952(94)00459-Y  1
1995 Harriss DR, Marsh KA, Birmingham AT, Hill SJ. Expression of muscarinic M3-receptors coupled to inositol phospholipid hydrolysis in human detrusor cultured smooth muscle cells. The Journal of Urology. 154: 1241-5. PMID 7637095 DOI: 10.1016/S0022-5347(01)67039-3  1
1994 Dickenson JM, Bulmer S, Whittaker A, Salwey M, Hawley J, Hill SJ. Bradykinin B2- and 5-hydroxytryptamine (5-HT2)-receptor stimulated increases in intracellular calcium in cultured guinea-pig aortic smooth muscle cells. Biochemical Pharmacology. 47: 947-52. PMID 8147914  0.36
1994 Dickenson JM, Hill SJ. Interactions between adenosine A1- and histamine H1-receptors. The International Journal of Biochemistry. 26: 959-69. PMID 8088416 DOI: 10.1016/0020-711X(94)90066-3  1
1994 Iredale PA, Alexander SP, Hill SJ. Coupling of a transfected human brain A1 adenosine receptor in CHO-K1 cells to calcium mobilisation via a pertussis toxin-sensitive mechanism. British Journal of Pharmacology. 111: 1252-6. PMID 8032613  1
1994 Peakman MC, Hill SJ. Adenosine A2B-receptor-mediated cyclic AMP accumulation in primary rat astrocytes. British Journal of Pharmacology. 111: 191-8. PMID 8012696  1
1994 Alexander SP, Losinski A, Kendall DA, Hill SJ. A comparison of A2 adenosine receptor-induced cyclic AMP generation in cerebral cortex and relaxation of pre-contracted aorta. British Journal of Pharmacology. 111: 185-90. PMID 8012695  1
1994 Dickenson JM, Hill SJ. Selective potentiation of histamine H1-receptor stimulated calcium responses by 1,4-dithiothreitol in DDT1MF-2 cells. Biochemical Pharmacology. 48: 1721-8. PMID 7980641 DOI: 10.1016/0006-2952(94)90457-X  1
1994 Dickenson JM, Hill SJ. Characteristics of [3H]mepyramine binding in DDT1MF-2 cells: evidence for high affinity binding to a functional histamine H1 receptor. European Journal of Pharmacology. 268: 257-62. PMID 7957647 DOI: 10.1016/0922-4106(94)90196-1  1
1994 Marsh KA, Hill SJ. Des-Arg9-bradykinin-induced increases in intracellular calcium ion concentration in single bovine tracheal smooth muscle cells. British Journal of Pharmacology. 112: 934-8. PMID 7921623  1
1994 Peakman MC, Hill SJ. Endogenous expression of histamine H1 receptors functionally coupled to phosphoinositide hydrolysis in C6 glioma cells: regulation by cyclic AMP. British Journal of Pharmacology. 113: 1554-60. PMID 7889313  1
1994 Alexander SP, Curtis AR, Kendall DA, Hill SJ. A1 adenosine receptor inhibition of cyclic AMP formation and radioligand binding in the guinea-pig cerebral cortex. British Journal of Pharmacology. 113: 1501-7. PMID 7889308  1
1994 McCreath G, Hall IP, Hill SJ. Agonist-induced desensitization of histamine H1 receptor-mediated inositol phospholipid hydrolysis in human umbilical vein endothelial cells. British Journal of Pharmacology. 113: 823-30. PMID 7858873  1
1993 Iredale PA, Martin KF, Hill SJ, Kendall DA. The effects of beta-phorbol-12,13 dibutyrate on agonist-induced increases in [Ca2+]i in N1E-115 cells. Differential modulation of responses to angiotensin II and bradykinin. Biochemical Pharmacology. 45: 611-7. PMID 8442761 DOI: 10.1016/0006-2952(93)90134-I  1
1993 Dickenson JM, Hill SJ. Adenosine A1-receptor stimulated increases in intracellular calcium in the smooth muscle cell line, DDT1MF-2. British Journal of Pharmacology. 108: 85-92. PMID 8428218 DOI: 10.1111/j.1476-5381.1993.tb13444.x  1
1993 Dickenson JM, White TE, Hill SJ. The effects of elevated cyclic AMP levels on histamine-H1-receptor-stimulated inositol phospholipid hydrolysis and calcium mobilization in the smooth-muscle cell line DDT1MF-2. The Biochemical Journal. 292: 409-17. PMID 8389134  0.36
1993 White TE, Dickenson JM, Hill SJ. Histamine H1-receptor-mediated inositol phospholipid hydrolysis in DDT1MF-2 cells: agonist and antagonist properties. British Journal of Pharmacology. 108: 196-203. PMID 8381320  0.36
1993 Dickenson JM, Hill SJ. Intracellular cross-talk between receptors coupled to phospholipase C via pertussis toxin-sensitive and insensitive G-proteins in DDT1MF-2 cells. British Journal of Pharmacology. 109: 719-24. PMID 8358567 DOI: 10.1111/j.1476-5381.1993.tb13633.x  1
1993 Dickenson JM, Hill SJ. Homologous and heterologous desensitization of histamine H1- and ATP-receptors in the smooth muscle cell line, DDT1MF-2: the role of protein kinase C. British Journal of Pharmacology. 110: 1449-56. PMID 8306086  1
1993 Iredale PA, Hill SJ. Increases in intracellular calcium via activation of an endogenous P2-purinoceptor in cultured CHO-K1 cells. British Journal of Pharmacology. 110: 1305-10. PMID 8306069  1
1993 Dickenson JM, Hill SJ. Intracellular cross-talk between receptors coupled to phospholipase C via pertussis toxin sensitive and insensitive G-proteins. Biochemical Society Transactions. 21: 296S. PMID 8224444  1
1993 White TE, Hill SJ. Differential responses to histamine and cyclo-pentyladenosine in subclones of the DDT1MF-2 cell line. Biochemical Society Transactions. 21: 293S. PMID 8224441  1
1993 Marsh KA, Hill SJ. Characteristics of the bradykinin-induced changes in intracellular calcium ion concentration of single bovine tracheal smooth muscle cells. British Journal of Pharmacology. 110: 29-35. PMID 8220891 DOI: 10.1111/j.1476-5381.1993.tb13767.x  1
1993 Iredale PA, Fukui H, Hill SJ. High, stable expression of the bovine histamine H1-receptor coupled to [Ca2+]i mobilisation in CHO-K1 cells. Biochemical and Biophysical Research Communications. 195: 1294-300. PMID 8216261 DOI: 10.1006/bbrc.1993.2184  1
1993 Dickenson JM, Hill SJ. Coupling of histamine H1 and adenosine A1 receptors to phospholipase C in DDT1MF-2 cells: synergistic interactions and regulation by cyclic AMP. Biochemical Society Transactions. 21: 1124-9. PMID 8131910  1
1993 Iredale PA, Martin KF, Hill SJ, Kendall DA. The control of intracellular calcium and neurotransmitter release in guinea pig-derived cerebral cortical synaptoneurosomes. Biochemical Pharmacology. 45: 407-14. PMID 8094616 DOI: 10.1016/0006-2952(93)90077-A  1
1993 McCrea KE, Hill SJ. Salmeterol, a long-acting beta 2-adrenoceptor agonist mediating cyclic AMP accumulation in a neuronal cell line. British Journal of Pharmacology. 110: 619-26. PMID 7902176 DOI: 10.1111/j.1476-5381.1993.tb13856.x  1
1992 Hall IP, Hill SJ. Effects of isozyme selective phosphodiesterase inhibitors on bovine tracheal smooth muscle tone. Biochemical Pharmacology. 43: 15-7. PMID 1734897 DOI: 10.1016/0006-2952(92)90654-2  1
1992 Iredale PA, Martin KF, Hill SJ, Kendall DA. Agonist-induced changes in [Ca2+]i in N1E-115 cells: differential effects of bradykinin and carbachol. European Journal of Pharmacology. 226: 163-8. PMID 1639111 DOI: 10.1016/0922-4106(92)90178-X  1
1992 Dickenson JM, Hill SJ. Intracellular calcium measurements in response to histamine stimulation in DDT1 MF-2 cells. Biochemical Society Transactions. 20: 19S. PMID 1633944  1
1992 Dickenson JM, Hill SJ. Histamine H1-receptor-mediated calcium influx in DDT1MF-2 cells. The Biochemical Journal. 284: 425-31. PMID 1599428  1
1992 Iredale PA, Martin KF, Alexander SP, Hill SJ, Kendall DA. Inositol 1,4,5-trisphosphate generation and calcium mobilisation via activation of an atypical P2 receptor in the neuronal cell line, N1E-115. British Journal of Pharmacology. 107: 1083-7. PMID 1467830  1
1992 Iredale PA, Martin KF, Alexander SP, Hill SJ, Kendall DA. Qualitative differences in [Ca2+]i increases and InsP3 generation following stimulation of N1E-115 cells with micromolar and millimolar ATP. Biochemical Pharmacology. 44: 1479-87. PMID 1417971  1
1992 Alexander SP, Kendall DA, Hill SJ. Excitatory amino acid-induced phosphoinositide turnover in guinea pig cerebral cortical slices: selective enhancement by spermine of the response to DL-1-aminocyclopentane-trans-1,3-dicarboxylate. Journal of Neurochemistry. 59: 610-5. PMID 1352801  1
1992 Marsh KA, Hill SJ. Bradykinin B2 receptor-mediated phosphoinositide hydrolysis in bovine cultured tracheal smooth muscle cells. British Journal of Pharmacology. 107: 443-7. PMID 1330177 DOI: 10.1111/j.1476-5381.1992.tb12765.x  1
1992 White TE, Dickenson JM, Alexander SP, Hill SJ. Adenosine A1-receptor stimulation of inositol phospholipid hydrolysis and calcium mobilisation in DDT1 MF-2 cells. British Journal of Pharmacology. 106: 215-21. PMID 1324066  1
1992 Hawley J, Rubin PC, Hill SJ. Expression of 5-HT2- and bradykinin B2-receptors coupled to phosphoinositide hydrolysis in cultured guinea-pig aortic smooth muscle cells. Biochemical Society Transactions. 20: 21S. PMID 1321753  1
1992 Alexander SP, Kendall DA, Hill SJ. Spermine enhances calcium- and GTP analogue-stimulated particulate phosphoinositidase. Biochemical Society Transactions. 20: 20S. PMID 1321751  1
1992 Hill SJ. Multiple histamine receptors: properties and functional characteristics. Biochemical Society Transactions. 20: 122-5. PMID 1321744  1
1992 Cartmell J, Kemp JA, Alexander SP, Hill SJ, Kendall DA. Inhibition of forskolin-stimulated cyclic AMP formation by 1-aminocyclopentane-trans-1,3-dicarboxylate in guinea-pig cerebral cortical slices. Journal of Neurochemistry. 58: 1964-6. PMID 1313857  1
1992 Alexander SP, Curtis AR, Hill SJ, Kendall DA. Activation of a metabotropic excitatory amino acid receptor potentiates A2b adenosine receptor-stimulated cyclic AMP accumulation. Neuroscience Letters. 146: 231-3. PMID 1283452 DOI: 10.1016/0304-3940(92)90085-L  1
1991 Iredale PA, Ruck A, Martin KF, Kendall DA, Hill SJ. Histamine-induced changes in intracellular calcium in undifferentiated N1E-115 cells. Biochemical Society Transactions. 19: 6S. PMID 2037190  1
1991 Dickenson JM, Hill SJ. Histamine-stimulated increases in intracellular calcium in the smooth muscle cell line, DDT1MF-2. Biochemical Pharmacology. 42: 1545-50. PMID 1930281 DOI: 10.1016/0006-2952(91)90423-3  1
1991 Alexander SP, Hill SJ, Kendall DA. Do polyamines regulate the NMDA inhibition of muscarinic receptor-induced phosphoinositide turnover in guinea pig brain? Neuroscience Letters. 131: 167-70. PMID 1662340 DOI: 10.1016/0304-3940(91)90605-S  1
1991 Ruck A, Kendall DA, Hill SJ. Alpha- and beta-adrenoceptor regulation of cyclic AMP accumulation in cultured rat astrocytes. A comparison of primary protoplasmic and mixed fibrous/protoplasmic astroglial cultures. Biochemical Pharmacology. 42: 59-69. PMID 1648923 DOI: 10.1016/0006-2952(91)90681-T  1
1991 Hill SJ. Histamine receptors and interactions between second messenger transduction systems. Agents and Actions. Supplements. 33: 145-59. PMID 1647127  1
1990 Ottosson A, Hill SJ, Edvinsson L. Histamine receptors in brain vessels of guinea-pig: in-vitro pharmacology and ligand binding. Acta Physiologica Scandinavica. 140: 135-41. PMID 2177313 DOI: 10.1111/j.1748-1716.1990.tb08984.x  1
1990 Ruck A, Millns P, Kendall DA, Hill SJ. Expression of beta 2-adrenoceptors mediating cyclic AMP accumulation in astroglial and neuronal cell lines derived from the rat CNS. Biochemical Pharmacology. 40: 2371-5. PMID 2173929 DOI: 10.1016/0006-2952(90)90735-4  1
1990 Alexander SP, Hill SJ, Kendall DA. Differential effects of elevated calcium ion concentrations on inositol phospholipid responses in mouse and rat cerebral cortical slices. Biochemical Pharmacology. 40: 1793-9. PMID 2173588 DOI: 10.1016/0006-2952(90)90358-R  1
1990 Hill SJ. Distribution, properties, and functional characteristics of three classes of histamine receptor. Pharmacological Reviews. 42: 45-83. PMID 2164693  1
1990 Alexander SP, Hill SJ, Kendall DA. Is the adenosine receptor modulation of histamine-induced accumulation of inositol phosphates in cerebral cortical slices mediated by effects on calcium ion fluxes? Journal of Neurochemistry. 55: 1138-41. PMID 2118942  1
1990 Alexander SP, Hill SJ, Kendall DA. Excitatory amino acid-induced formation of inositol phosphates in guinea-pig cerebral cortical slices: involvement of ionotropic or metabotropic receptors? Journal of Neurochemistry. 55: 1439-41. PMID 1975837  1
1990 Donaldson J, Kendall DA, Hill SJ. Discriminatory effects of forskolin and EGTA on the indirect cyclic AMP responses to histamine, noradrenaline, 5-hydroxytryptamine, and glutamate in guinea-pig cerebral cortical slices. Journal of Neurochemistry. 54: 1484-91. PMID 1969933  1
1990 Hall IP, Donaldson J, Hill SJ. Modulation of fluoroaluminate-induced inositol phosphate formation by increases in tissue cyclic AMP content in bovine tracheal smooth muscle. British Journal of Pharmacology. 100: 646-50. PMID 1697201  1
1990 Hall IP, Donaldson J, Hill SJ. Modulation of carbachol-induced inositol phosphate formation in bovine tracheal smooth muscle by cyclic AMP phosphodiesterase inhibitors. Biochemical Pharmacology. 39: 1357-63. PMID 1690998 DOI: 10.1016/0006-2952(90)90013-B  1
1989 Alexander SP, Hill SJ, Kendall DA. The 2-chloroadenosine inhibition of histamine-induced inositol phosphates accumulation in mouse brain and calcium ions. British Journal of Pharmacology. 98: 832P. PMID 2611535  1
1989 Hill SJ, Kendall DA. Cross-talk between different receptor-effector systems in the mammalian CNS. Cellular Signalling. 1: 135-41. PMID 2561981 DOI: 10.1016/0898-6568(89)90002-8  1
1989 Donaldson J, Brown AM, Hill SJ. Temporal changes in the calcium-dependence of the histamine H1-receptor-stimulation of cyclic AMP accumulation in guinea-pig cerebral cortex. British Journal of Pharmacology. 98: 1365-75. PMID 2558762  1
1989 Hall IP, Donaldson J, Hill SJ. Inhibition of histamine-stimulated inositol phospholipid hydrolysis by agents which increase cyclic AMP levels in bovine tracheal smooth muscle. British Journal of Pharmacology. 97: 603-13. PMID 2547479  1
1989 Hall IP, Hill SJ. Inhibition by salbutamol, forskolin and IBMX of AlF4-induced inositol phosphate formation in bovine airway smooth muscle. British Journal of Pharmacology. 98: 788P. PMID 2482107  1
1989 Alexander SP, Kendall DA, Hill SJ. Differences in the adenosine receptors modulating inositol phosphates and cyclic AMP accumulation in mammalian cerebral cortex. British Journal of Pharmacology. 98: 1241-8. PMID 2482102  1
1989 Stanley C, Brown AM, Hill SJ. Effect of isozyme-selective inhibitors of phosphodiesterase on histamine-stimulated cyclic AMP accumulation in guinea-pig hippocampus. Journal of Neurochemistry. 52: 671-6. PMID 2465375  1
1988 Kendall DA, Hill SJ. Adenosine inhibition of histamine-stimulated inositol phospholipid hydrolysis in mouse cerebral cortex. Journal of Neurochemistry. 50: 497-502. PMID 3335859  1
1988 Young CS, Mason R, Hill SJ. Studies on the mechanism of histamine-induced release of noradrenaline and 5-hydroxytryptamine from slices of rat cerebral cortex. Biochemical Pharmacology. 37: 2799-805. PMID 3260780 DOI: 10.1016/0006-2952(88)90043-3  1
1988 Hall IP, Hill SJ. Beta-adrenoceptor stimulation inhibits histamine-stimulated inositol phospholipid hydrolysis in bovine tracheal smooth muscle. British Journal of Pharmacology. 95: 1204-12. PMID 2905910 DOI: 10.1111/j.1476-5381.1988.tb11757.x  1
1988 Young CS, Mason R, Hill SJ. Inhibition by H1-antihistamines of the uptake of noradrenaline and 5-HT into rat brain synaptosomes. Biochemical Pharmacology. 37: 976-8. PMID 2894209 DOI: 10.1016/0006-2952(88)90194-3  1
1988 Donaldson J, Hill SJ, Brown AM. Kinetic studies on the mechanism by which histamine H1 receptors potentiate cyclic AMP accumulation in guinea pig cerebral cortical slices. Molecular Pharmacology. 33: 626-33. PMID 2837636  1
1988 Donaldson J, Brown AM, Hill SJ. Influence of rolipram on the cyclic 3',5'-adenosine monophosphate response to histamine and adenosine in slices of guinea-pig cerebral cortex. Biochemical Pharmacology. 37: 715-23. PMID 2829922 DOI: 10.1016/0006-2952(88)90146-3  1
1988 Hill SJ, Straw RM. Alpha 2-adrenoceptor-mediated inhibition of histamine release from rat cerebral cortical slices. British Journal of Pharmacology. 95: 1213-9. PMID 2464390 DOI: 10.1111/j.1476-5381.1988.tb11758.x  1
1987 Hill SJ, Kendall DA. Studies on the adenosine-receptor mediating the augmentation of histamine-induced inositol phospholipid hydrolysis in guinea-pig cerebral cortex. British Journal of Pharmacology. 91: 661-9. PMID 3038249 DOI: 10.1111/j.1476-5381.1987.tb11260.x  1
1987 Al-Gadi M, Hill SJ. The role of calcium in the cyclic AMP response to histamine in rabbit cerebral cortical slices. British Journal of Pharmacology. 91: 213-22. PMID 3036288 DOI: 10.1111/j.1476-5381.1987.tb09001.x  1
1987 Hill SJ. Histamine receptors branch out. Nature. 327: 104-5. PMID 3033514 DOI: 10.1038/327104a0  1
1987 Donaldson J, Hill SJ. 1,4-Dithiothreitol-induced changes in histamine H1-agonist efficacy and affinity in the longitudinal smooth muscle of guinea-pig ileum. British Journal of Pharmacology. 90: 263-71. PMID 2880626 DOI: 10.1111/j.1476-5381.1987.tb16848.x  1
1987 Hill SJ. Histamine receptors in the mammalian central nervous system: biochemical studies. Progress in Medicinal Chemistry. 24: 29-84. PMID 2849144  1
1986 Donaldson J, Hill SJ. 1,4-Dithiothreitol-induced alteration in histamine H1-agonist binding in guinea-pig cerebellum and cerebral cortex. European Journal of Pharmacology. 129: 25-31. PMID 3770075 DOI: 10.1016/0014-2999(86)90332-8  1
1986 Donaldson J, Hill SJ. Histamine-induced hydrolysis of polyphosphoinositides in guinea-pig ileum and brain. European Journal of Pharmacology. 124: 255-65. PMID 3732381 DOI: 10.1016/0014-2999(86)90226-8  1
1986 Donaldson J, Hill SJ. Enhancement of histamine H1-receptor agonist activity by 1,4-dithiothreitol in guinea-pig cerebellum and cerebral cortex. Journal of Neurochemistry. 47: 1476-82. PMID 3020176  1
1986 Donaldson J, Hill SJ. Selective enhancement of histamine H1-receptor responses in guinea-pig ileal smooth muscle by 1,4-dithiothreitol. British Journal of Pharmacology. 87: 191-9. PMID 2937501 DOI: 10.1111/j.1476-5381.1986.tb10171.x  1
1985 Al-Gadi M, Hill SJ. Characterization of histamine receptors mediating the stimulation of cyclic AMP accumulation in rabbit cerebral cortical slices. British Journal of Pharmacology. 85: 877-88. PMID 2994788 DOI: 10.1111/j.1476-5381.1985.tb11087.x  1
1985 Donaldson J, Hill SJ. Histamine-induced inositol phospholipid breakdown in the longitudinal smooth muscle of guinea-pig ileum. British Journal of Pharmacology. 85: 499-512. PMID 2992666 DOI: 10.1111/j.1476-5381.1985.tb08887.x  1
1983 Hadfield AJ, Robinson NR, Hill SJ. The nature of the binding of [3H]mepyramine to homogenates of guinea-pig cerebral cortex at different [3H]ligand concentrations. Biochemical Pharmacology. 32: 2449-51. PMID 6615545 DOI: 10.1016/0006-2952(83)90690-1  1
1981 Hill SJ, Daum P, Young JM. Affinities of histamine H1-antagonists in guinea pig brain: similarity of values determined from [3H]mepyramine binding and from inhibition of a functional response. Journal of Neurochemistry. 37: 1357-60. PMID 6117608 DOI: 10.1111/j.1471-4159.1981.tb04692.x  1
1981 Hill SJ, Young JM. Characterization of [3H]mepyramine binding to the longitudinal muscle of guinea pig small intestine. Molecular Pharmacology. 19: 379-87. PMID 6115306  1
1980 Hill SJ, Young JM. Histamine H1-receptors in the brain of the guinea-pig and the rat: differences in ligand binding properties and regional distribution. British Journal of Pharmacology. 68: 687-96. PMID 7378642 DOI: 10.1111/j.1476-5381.1980.tb10861.x  1
1979 Hill SJ, Young JM. The binding properties of [3H]-mepyramine in the brain of the guinea-pig and the rat [proceedings]. British Journal of Pharmacology. 66: 93P. PMID 454974  1
1978 Hill SJ, Young JM. Evidence for the presence of histamine H1-receptors in guinea-pig brain [proceedings]. British Journal of Pharmacology. 63: 394P. PMID 667469  1
1978 Hill SJ, Young M. Antagonism of central histamine H1 receptors by antipsychotic drugs. European Journal of Pharmacology. 52: 397-9. PMID 32056 DOI: 10.1016/0014-2999(78)90297-2  1
Show low-probability matches.