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Carla Mattos - Publications

Affiliations: 
2012 North Carolina State University, Raleigh, NC 
 2012- Northeastern University, Boston, MA, United States 
Area:
Biochemistry
Website:
https://cos.northeastern.edu/faculty/carla-mattos/
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68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Johnson CW, Fetics SK, Davis KP, Rodrigues JA, Mattos C. Allosteric site variants affect GTP hydrolysis on Ras. Protein Science : a Publication of the Protein Society. e4767. PMID 37615343 DOI: 10.1002/pro.4767  0.819
2022 Volmar AY, Guterres H, Zhou H, Reid D, Pavlopoulos S, Makowski L, Mattos C. Mechanisms of isoform-specific residue influence on GTP-bound HRas, KRas and NRas. Biophysical Journal. PMID 35794829 DOI: 10.1016/j.bpj.2022.07.005  0.801
2022 Li ZL, Mattos C, Buck M. Computational studies of the principle of dynamic-change-driven protein interactions. Structure (London, England : 1993). PMID 35381186 DOI: 10.1016/j.str.2022.03.008  0.349
2022 Johnson CW, Seo HS, Terrell EM, Yang MH, KleinJan F, Gebregiworgis T, Gasmi-Seabrook GMC, Geffken EA, Lakhani J, Song K, Bashyal P, Popow O, Paulo JA, Liu A, Mattos C, et al. Regulation of GTPase function by autophosphorylation. Molecular Cell. PMID 35202574 DOI: 10.1016/j.molcel.2022.02.011  0.396
2021 Cookis T, Mattos C. Crystal Structure Reveals the Full Ras-Raf Interface and Advances Mechanistic Understanding of Raf Activation. Biomolecules. 11. PMID 34356620 DOI: 10.3390/biom11070996  0.424
2021 Packer MR, Parker JA, Chung JK, Li Z, Lee YK, Cookis T, Guterres H, Alvarez S, Hossain MA, Donnelly DP, Agar JN, Makowski L, Buck M, Groves JT, Mattos C. Raf promotes dimerization of the Ras G-domain with increased allosteric connections. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33653954 DOI: 10.1073/pnas.2015648118  0.401
2020 Agarwal S, Smith M, De La Rosa I, Verba KA, Swartz P, Segura-Totten M, Mattos C. Development of a structure-analysis pipeline using multiple-solvent crystal structures of barrier-to-autointegration factor. Acta Crystallographica. Section D, Structural Biology. 76: 1001-1014. PMID 33021502 DOI: 10.1107/S2059798320011341  0.372
2020 Ojeda M, Johnson C, Mattos C. Determining conformational dynamics of the allosteric site in HRas R97G The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04065  0.349
2020 Packer MR, Parker JA, Chung JK, Li Z, Lee YK, Guterres H, Cookis T, Hossain A, Donnelly DP, Agar JN, Makowski L, Buck M, Groves JT, Mattos C. Raf promotes dimerization of the Ras G‐domain The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03461  0.426
2020 Volmar AY, Guterres H, Zhou H, Mattos C, Makowski L. Ras Structure, Dynamics and Conformational States Assessed by MD Simulations and Solution Wide angle X‐ray Scattering The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03160  0.785
2020 Schwabe M, Holzapfel G, Mattos C. Exploring the Rap1A Active Site Through Accelerated Molecular Dynamic Simulations The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02775  0.564
2020 Cookis T, Volmar A, Merritt K, Mattos C. Interaction between Ras and the two Ras‐Binding Domains of Raf kinase The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02405  0.774
2019 Jang H, Banerjee A, Marcus K, Makowski L, Mattos C, Gaponenko V, Nussinov R. The Structural Basis of the Farnesylated and Methylated KRas4B Interaction with Calmodulin. Structure (London, England : 1993). PMID 31495533 DOI: 10.1016/J.Str.2019.08.009  0.339
2019 Marcus K, Mattos C. Water in Ras Superfamily Evolution. Journal of Computational Chemistry. PMID 31483874 DOI: 10.1002/Jcc.26060  0.443
2019 Johnson CW, Lin YJ, Reid D, Parker J, Pavlopoulos S, Dischinger P, Graveel C, Aguirre AJ, Steensma M, Haigis KM, Mattos C. Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D. Cell Reports. 28: 1538-1550.e7. PMID 31390567 DOI: 10.1016/J.Celrep.2019.07.026  0.464
2019 Kearney BM, Schwabe M, Marcus K, Roberts DM, Dechene M, Swartz P, Mattos C. DRoP: Automated detection of conserved solvent binding sites on proteins. Proteins. PMID 31294888 DOI: 10.1002/Prot.25781  0.751
2019 Knihtila R, Volmar AY, Meilleur F, Mattos C. Titration of ionizable groups in proteins using multiple neutron data sets from a single crystal: application to the small GTPase Ras. Acta Crystallographica. Section F, Structural Biology Communications. 75: 111-115. PMID 30713162 DOI: 10.1107/S2053230X18018125  0.801
2018 Ashkar R, Bilheux HZ, Bordallo H, Briber R, Callaway DJE, Cheng X, Chu XQ, Curtis JE, Dadmun M, Fenimore P, Fushman D, Gabel F, Gupta K, Herberle F, Heinrich F, ... ... Mattos C, et al. Neutron scattering in the biological sciences: progress and prospects. Acta Crystallographica. Section D, Structural Biology. 74: 1129-1168. PMID 30605130 DOI: 10.1107/S2059798318017503  0.642
2018 Zhou H, Guterres H, Mattos C, Makowski L. Predicting X-ray solution scattering from flexible macromolecules. Protein Science : a Publication of the Protein Society. PMID 30230663 DOI: 10.1002/Pro.3508  0.401
2018 Parker JA, Volmar AY, Pavlopoulos S, Mattos C. K-Ras Populates Conformational States Differently from Its Isoform H-Ras and Oncogenic Mutant K-RasG12D. Structure (London, England : 1993). PMID 29706533 DOI: 10.1016/J.Str.2018.03.018  0.787
2017 Parker JA, Mattos C. The K-Ras, N-Ras, and H-Ras Isoforms: Unique Conformational Preferences and Implications for Targeting Oncogenic Mutants. Cold Spring Harbor Perspectives in Medicine. PMID 29038336 DOI: 10.1101/Cshperspect.A031427  0.468
2017 Kauke MJ, Traxlmayr MW, Parker JA, Kiefer JD, Knihtila R, McGee J, Verdine G, Mattos C, Wittrup KD. An engineered protein antagonist of K-Ras/B-Raf interaction. Scientific Reports. 7: 5831. PMID 28724936 DOI: 10.1038/S41598-017-05889-7  0.483
2017 Johnson CW, Reid D, Parker JA, Salter S, Knihtila R, Kuzmic P, Mattos C. The small GTPases K-Ras, N-Ras and H-Ras have distinct biochemical properties determined by allosteric effects. The Journal of Biological Chemistry. PMID 28630043 DOI: 10.1074/Jbc.M117.778886  0.49
2017 Zhou H, Guterres H, Mattos C, Makowski L. Verifying Self-Consistency of Protein Structure and Dynamics through MD Simulation and WAXS Biophysical Journal. 112: 176a. DOI: 10.1016/J.Bpj.2016.11.972  0.418
2016 Johnson CW, Buhrman G, Ting PY, Colicelli J, Mattos C. Expression, purification, crystallization and X-ray data collection for RAS and its mutants. Data in Brief. 6: 423-7. PMID 26866052 DOI: 10.1016/J.Dib.2015.12.007  0.504
2015 Knihtila R, Holzapfel G, Weiss K, Meilleur F, Mattos C. Neutron Crystal Structure of RAS GTPase puts in question the Protonation State of the GTP γ-Phosphate. The Journal of Biological Chemistry. PMID 26515069 DOI: 10.1074/Jbc.M115.679860  0.698
2015 Mattos C. Ras: structural details to guide direct targeting. Aging. 7: 344-5. PMID 26080945  0.328
2015 Ting PY, Johnson CW, Fang C, Cao X, Graeber TG, Mattos C, Colicelli J. Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 25999467 DOI: 10.1096/Fj.15-271510  0.494
2015 Marcus K, Mattos C. Direct Attack on RAS: Intramolecular Communication and Mutation-Specific Effects. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1810-8. PMID 25878362 DOI: 10.1158/1078-0432.Ccr-14-2148  0.5
2015 Fetics SK, Guterres H, Kearney BM, Buhrman G, Ma B, Nussinov R, Mattos C. Allosteric effects of the oncogenic RasQ61L mutant on Raf-RBD. Structure (London, England : 1993). 23: 505-16. PMID 25684575 DOI: 10.1016/J.Str.2014.12.017  0.788
2015 Parker JA, Mattos C. The Ras-Membrane Interface: Isoform-specific Differences in The Catalytic Domain. Molecular Cancer Research : McR. 13: 595-603. PMID 25566993 DOI: 10.1158/1541-7786.Mcr-14-0535  0.495
2014 Kearney BM, Johnson CW, Roberts DM, Swartz P, Mattos C. DRoP: a water analysis program identifies Ras-GTP-specific pathway of communication between membrane-interacting regions and the active site. Journal of Molecular Biology. 426: 611-29. PMID 24189050 DOI: 10.1016/J.Jmb.2013.10.036  0.824
2013 Johnson CW, Mattos C. The allosteric switch and conformational states in Ras GTPase affected by small molecules. The Enzymes. 33: 41-67. PMID 25033800 DOI: 10.1016/B978-0-12-416749-0.00003-8  0.473
2013 Nussinov R, Tsai CJ, Mattos C. 'Pathway drug cocktail': targeting Ras signaling based on structural pathways. Trends in Molecular Medicine. 19: 695-704. PMID 23953481 DOI: 10.1016/J.Molmed.2013.07.009  0.397
2012 Holzapfel G, Buhrman G, Mattos C. Shift in the equilibrium between on and off states of the allosteric switch in Ras-GppNHp affected by small molecules and bulk solvent composition. Biochemistry. 51: 6114-26. PMID 22845804 DOI: 10.1021/Bi300509J  0.681
2012 Walters J, Schipper JL, Swartz P, Mattos C, Clark AC. Allosteric modulation of caspase 3 through mutagenesis. Bioscience Reports. 32: 401-11. PMID 22607239 DOI: 10.1042/Bsr20120037  0.415
2012 Prior IA, Lewis PD, Mattos C. A comprehensive survey of Ras mutations in cancer. Cancer Research. 72: 2457-67. PMID 22589270 DOI: 10.1158/0008-5472.Can-11-2612  0.406
2012 Gagnon KT, Biswas S, Zhang X, Brown BA, Wollenzien P, Mattos C, Maxwell ES. Structurally conserved Nop56/58 N-terminal domain facilitates archaeal box C/D ribonucleoprotein-guided methyltransferase activity. The Journal of Biological Chemistry. 287: 19418-28. PMID 22496443 DOI: 10.1074/Jbc.M111.323253  0.392
2011 Buhrman G, O'Connor C, Zerbe B, Kearney BM, Napoleon R, Kovrigina EA, Vajda S, Kozakov D, Kovrigin EL, Mattos C. Analysis of binding site hot spots on the surface of Ras GTPase. Journal of Molecular Biology. 413: 773-89. PMID 21945529 DOI: 10.1016/J.Jmb.2011.09.011  0.821
2011 Biswas S, Buhrman G, Gagnon K, Mattos C, Brown BA, Maxwell ES. Comparative analysis of the 15.5kD box C/D snoRNP core protein in the primitive eukaryote Giardia lamblia reveals unique structural and functional features. Biochemistry. 50: 2907-18. PMID 21366326 DOI: 10.1021/Bi1020474  0.379
2011 Walters J, Swartz P, Mattos C, Clark AC. Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3. Archives of Biochemistry and Biophysics. 508: 31-8. PMID 21266160 DOI: 10.1016/J.Abb.2011.01.011  0.362
2011 Buhrman G, Kumar VS, Cirit M, Haugh JM, Mattos C. Allosteric modulation of Ras-GTP is linked to signal transduction through RAF kinase. The Journal of Biological Chemistry. 286: 3323-31. PMID 21098031 DOI: 10.1074/Jbc.M110.193854  0.47
2010 Buhrman G, Holzapfel G, Fetics S, Mattos C. Allosteric modulation of Ras positions Q61 for a direct role in catalysis. Proceedings of the National Academy of Sciences of the United States of America. 107: 4931-6. PMID 20194776 DOI: 10.1073/Pnas.0912226107  0.818
2009 Walters J, Pop C, Scott FL, Drag M, Swartz P, Mattos C, Salvesen GS, Clark AC. A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis. The Biochemical Journal. 424: 335-45. PMID 19788411 DOI: 10.1042/Bj20090825  0.329
2009 Dechene M, Wink G, Smith M, Swartz P, Mattos C. Multiple solvent crystal structures of ribonuclease A: an assessment of the method. Proteins. 76: 861-81. PMID 19291738 DOI: 10.1002/Prot.22393  0.78
2009 Brenke R, Kozakov D, Chuang GY, Beglov D, Hall D, Landon MR, Mattos C, Vajda S. Fragment-based identification of druggable 'hot spots' of proteins using Fourier domain correlation techniques. Bioinformatics (Oxford, England). 25: 621-7. PMID 19176554 DOI: 10.1093/Bioinformatics/Btp036  0.365
2008 Mattos C, Clark AC. Minimizing frustration by folding in an aqueous environment. Archives of Biochemistry and Biophysics. 469: 118-31. PMID 17719000 DOI: 10.1016/J.Abb.2007.07.007  0.326
2007 Buhrman G, Wink G, Mattos C. Transformation efficiency of RasQ61 mutants linked to structural features of the switch regions in the presence of Raf. Structure (London, England : 1993). 15: 1618-29. PMID 18073111 DOI: 10.1016/J.Str.2007.10.011  0.453
2007 Milam SL, Nicely NI, Feeney B, Mattos C, Clark AC. Rapid folding and unfolding of Apaf-1 CARD. Journal of Molecular Biology. 369: 290-304. PMID 17408690 DOI: 10.1016/J.Jmb.2007.02.105  0.697
2007 Buhrman G, Wink G, Mattos C. The structures of Q61 Ras mutants solved in a new space group reveals insights into the mechanism of intrinsic GTPase actitvity The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A640-C  0.4
2007 Holzapfel GA, Miller CM, Mattos C. The crystal structures of Rap1a bound to GTP and GppNHp The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A640  0.659
2007 Subbiah SKV, Moe J, Desai D, Holzapfel GA, Wink G, Swartz P, Mattos C. Multiple Solvent Crystal Structures of Chymotrypsin: Comparision with Elastase The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A639  0.625
2007 De la Rosa I, Segura‐Totten M, Mattos C. Barrier‐to‐autointegration Factor (BAF): purification, crystallization and multiple solvent crystal structure The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A638-E  0.389
2006 Feeney B, Pop C, Swartz P, Mattos C, Clark AC. Role of loop bundle hydrogen bonds in the maturation and activity of (Pro)caspase-3. Biochemistry. 45: 13249-63. PMID 17073446 DOI: 10.1021/Bi0611964  0.375
2006 Mattos C, Bellamacina CR, Peisach E, Pereira A, Vitkup D, Petsko GA, Ringe D. Multiple solvent crystal structures: probing binding sites, plasticity and hydration. Journal of Molecular Biology. 357: 1471-82. PMID 16488429 DOI: 10.1016/J.Jmb.2006.01.039  0.771
2005 Buhrman G, Parker B, Sohn J, Rudolph J, Mattos C. Structural mechanism of oxidative regulation of the phosphatase Cdc25B via an intramolecular disulfide bond. Biochemistry. 44: 5307-16. PMID 15807524 DOI: 10.1021/Bi047449F  0.373
2004 Nicely NI, Kosak J, de Serrano V, Mattos C. Crystal structures of Ral-GppNHp and Ral-GDP reveal two binding sites that are also present in Ras and Rap. Structure (London, England : 1993). 12: 2025-36. PMID 15530367 DOI: 10.1016/J.Str.2004.08.011  0.779
2004 Mattos C, Cohen JD, Green DF, Tidor B, Karplus M. X-ray structural and simulation analysis of a protein mutant: the value of a combined approach. Proteins. 55: 733-42. PMID 15103635 DOI: 10.1002/Prot.20031  0.71
2003 Buhrman G, de Serrano V, Mattos C. Organic solvents order the dynamic switch II in Ras crystals. Structure (London, England : 1993). 11: 747-51. PMID 12842038 DOI: 10.1016/S0969-2126(03)00128-X  0.505
2002 Mattos C. Protein-water interactions in a dynamic world. Trends in Biochemical Sciences. 27: 203-8. PMID 11943548 DOI: 10.1016/S0968-0004(02)02067-4  0.356
2001 Mattos C, Ringe D. Proteins in organic solvents. Current Opinion in Structural Biology. 11: 761-4. PMID 11751059 DOI: 10.1016/S0959-440X(01)00278-0  0.435
1999 Ringe D, Mattos C. Analysis of the binding surfaces of proteins. Medicinal Research Reviews. 19: 321-31. PMID 10398928 DOI: 10.1002/(Sici)1098-1128(199907)19:4<321::Aid-Med5>3.0.Co;2-F  0.44
1998 MacKerell AD, Bashford D, Bellott M, Dunbrack RL, Evanseck JD, Field MJ, Fischer S, Gao J, Guo H, Ha S, Joseph-McCarthy D, Kuchnir L, Kuczera K, Lau FT, Mattos C, et al. All-atom empirical potential for molecular modeling and dynamics studies of proteins. The Journal of Physical Chemistry. B. 102: 3586-616. PMID 24889800 DOI: 10.1021/Jp973084F  0.711
1996 Mattos C, Ringe D. Locating and Characterizing Binding Sites on Proteins Nature Biotechnology. 14: 595-599. PMID 9630949 DOI: 10.1038/Nbt0596-595  0.465
1996 Allen KN, Bellamacina CR, Ding X, Jeffery CJ, Mattos C, Petsko GA, Ringe D. An Experimental Approach to Mapping the Binding Surfaces of Crystalline Proteins† The Journal of Physical Chemistry. 100: 2605-2611. DOI: 10.1021/Jp952516O  0.782
1995 Mattos C, Giammona DA, Petsko GA, Ringe D. Structural analysis of the active site of porcine pancreatic elastase based on the X-ray crystal structures of complexes with trifluoroacetyl-dipeptide-anilide inhibitors Biochemistry. 34: 3193-3203. PMID 7880814 DOI: 10.1021/Bi00010A008  0.557
1994 Mattos C, Petsko GA, Karplus M. Analysis of two-residue turns in proteins Journal of Molecular Biology. 238: 733-747. PMID 8182746 DOI: 10.1006/Jmbi.1994.1332  0.614
1994 Mattos C, Rasmussen B, Ding X, Petsko GA, Ringe D. Analogous inhibitors of elastase do not always bind analogously Nature Structural Biology. 1: 55-58. PMID 7656008 DOI: 10.1038/Nsb0194-55  0.548
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