Year |
Citation |
Score |
2023 |
Lakshman MK, Sebastian D, Pradhan P, Neary MC, Piette AM, Trzebiatowski SP, Henriques AEK, Willoughby PH. Nitrene C-H Bond Insertion Approach to Carbazolones and Indolones, and a Reactivity Departure for 7-Membered Analogues. Chemistry (Weinheim An Der Bergstrasse, Germany). e202302995. PMID 37751465 DOI: 10.1002/chem.202302995 |
0.376 |
|
2022 |
Sebastian D, Willoughby PH, Lakshman MK. Cross-dehydrogenative coupling of ethers and amides with tautomerizable quinazolinones and mechanistic studies. Organic & Biomolecular Chemistry. PMID 35796592 DOI: 10.1039/d2ob00874b |
0.333 |
|
2022 |
Akula HK, Bae S, Pradhan P, Yang L, Zajc B, Lakshman MK. Diversely C8-functionalized adenine nucleosides their underexplored carboxaldehydes. Chemical Communications (Cambridge, England). PMID 35029254 DOI: 10.1039/d1cc06686b |
0.304 |
|
2022 |
Singh MK, Lakshman MK. Recent developments in the utility of saturated azaheterocycles in peptidomimetics. Organic & Biomolecular Chemistry. PMID 35018952 DOI: 10.1039/d1ob01329g |
0.41 |
|
2021 |
Sebastian D, Satishkumar S, Pradhan P, Yang L, Lakshman MK. General Approach to ,C5'-Difunctionalization of Adenosine. The Journal of Organic Chemistry. PMID 34905365 DOI: 10.1021/acs.joc.1c01587 |
0.433 |
|
2020 |
Korvinson KA, Akula HK, Malinchak CT, Sebastian D, Wei W, Khandaker TA, Andrzejewska MR, Zajc B, Lakshman MK. Catalytic Reductions Without External Hydrogen Gas: Broad Scope Hydrogenations with Tetrahydroxydiboron and a Tertiary Amine. Advanced Synthesis & Catalysis. 362: 166-176. PMID 33071705 DOI: 10.1002/adsc.201901099 |
0.331 |
|
2019 |
Khandaker TA, Hess JD, Aguilera R, Andrei G, Snoeck R, Schols D, Pradhan P, Lakshman MK. Synthesis and Evaluations of "1,4-Triazolyl Combretacoumarins" and Desmethoxy Analogues. European Journal of Organic Chemistry. 2019: 5610-5623. PMID 31579393 DOI: 10.1002/Ejoc.201900569 |
0.415 |
|
2019 |
Akula HK, Lakshman MK. Facile Modifications at the C4 Position of Pyrimidine Nucleosides via In Situ Amide Activation with 1H-Benzotriazol-1-yloxy-tris(dimethyl-amino)phosphonium Hexafluorophosphate. Current Protocols in Nucleic Acid Chemistry. e73. PMID 30688408 DOI: 10.1002/Cpnc.73 |
0.509 |
|
2018 |
Andrzejewska MR, Vuram PK, Pottabathini N, Gurram V, Relangi SS, Korvinson KA, Doddipalla R, Stahl L, Neary MC, Pradhan P, Sharma S, Lakshman MK. The Disappearing Director: The Case of Directed -Arylation a Removable Hydroxyl Group. Advanced Synthesis & Catalysis. 360: 2503-2510. PMID 30559638 DOI: 10.1002/Adsc.201701611 |
0.477 |
|
2018 |
Lakshman MK, Zajc B. When nucleoside chemistry met hypervalent iodine reagents. Arkivoc : Free Online Journal of Organic Chemistry. 2018: 252-279. PMID 30221252 DOI: 10.24820/Ark.5550190.P010.281 |
0.467 |
|
2017 |
Satishkumar S, Poudapally S, Vuram PK, Gurram V, Pottabathini N, Sebastian D, Yang L, Pradhan P, Lakshman MK. Pd-catalyzeduncatalyzed, PhI(OAc)-mediated cyclization reactions of-([1,1'-biaryl]-2-yl)adenine nucleosides. Chemcatchem. 9: 4058-4069. PMID 29503672 DOI: 10.1002/Cctc.201700918 |
0.473 |
|
2017 |
Lakshman MK, Vuram PK. Cross-dehydrogenative coupling and oxidative-amination reactions of ethers and alcohols with aromatics and heteroaromatics. Chemical Science. 8: 5845-5888. PMID 28970941 DOI: 10.1039/C7Sc01045A |
0.439 |
|
2017 |
Lakshman MK, Tine FA, Khandaker TA, Basava V, Agyemang NB, Benavidez MSA, Gaši M, Guerrera L, Zajc B. KHF2, a mild and selective desilylating agent for phenol t-butyldimethylsilyl (TBDMS) ethers. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 28: 381-385. PMID 28713205 DOI: 10.1055/S-0036-1588350 |
0.369 |
|
2017 |
Akula HK, Kokatla H, Andrei G, Snoeck R, Schols D, Balzarini J, Yang L, Lakshman MK. Correction: Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products. Organic & Biomolecular Chemistry. PMID 28101554 DOI: 10.1039/C7Ob90013A |
0.309 |
|
2017 |
Akula HK, Kokatla H, Andrei G, Snoeck R, Schols D, Balzarini J, Yang L, Lakshman MK. Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products. Organic & Biomolecular Chemistry. PMID 28054092 DOI: 10.1039/c6ob02334g |
0.345 |
|
2017 |
Satishkumar S, Poudapally S, Vuram PK, Gurram V, Pottabathini N, Sebastian D, Yang L, Pradhan P, Lakshman MK. Pd-Catalyzed versus Uncatalyzed, PhI(OAc)2
-Mediated Cyclization Reactions of N
6
-([1,1′-Biaryl]-2-yl)Adenine Nucleosides Chemcatchem. 9: 4017-4018. DOI: 10.1002/CCTC.201701686 |
0.368 |
|
2017 |
Satishkumar S, Poudapally S, Vuram PK, Gurram V, Pottabathini N, Sebastian D, Yang L, Pradhan P, Lakshman MK. Front Cover: Pd-Catalyzed versus Uncatalyzed, PhI(OAc)2
-Mediated Cyclization Reactions of N
6
-([1,1′-Biaryl]-2-yl)Adenine Nucleosides (ChemCatChem 21/2017) Chemcatchem. 9: 4014-4014. DOI: 10.1002/Cctc.201701672 |
0.469 |
|
2016 |
Satishkumar S, Lakshman MK. Benzimidazopurine nucleosides from N(6)-aryl adenosine derivatives by PhI(OAc)2-mediated C-N bond formation, no metal needed. Chemical Communications (Cambridge, England). PMID 27976760 DOI: 10.1039/C6Cc07722F |
0.453 |
|
2016 |
Singh MK, Akula HK, Satishkumar S, Stahl L, Lakshman MK. Ruthenium-Catalyzed C-H Bond Activation Approach to Azolyl Aminals and Hemiaminal Ethers, Mechanistic Evaluations, and Isomer Interconversion. Acs Catalysis. 6: 1921-1928. PMID 27563492 DOI: 10.1021/Acscatal.5B02603 |
0.646 |
|
2016 |
Basava V, Yang L, Pradhan P, Lakshman MK. A novel bis(pinacolato)diboron-mediated N-O bond deoxygenative route to C6 benzotriazolyl purine nucleoside derivatives. Organic & Biomolecular Chemistry. PMID 27377367 DOI: 10.1039/C6Ob01170E |
0.496 |
|
2016 |
Singh MK, Akula HK, Satishkumar S, Stahl L, Lakshman MK. Ruthenium-Catalyzed C-H Bond Activation Approach to Azolyl Aminals and Hemiaminal Ethers, Mechanistic Evaluations, and Isomer Interconversion Acs Catalysis. 6: 1921-1928. DOI: 10.1021/acscatal.5b02603 |
0.605 |
|
2016 |
Singh MK, Lakshman MK. ChemInform Abstract: Diarylmethanes Through an Unprecedented Palladium-Catalyzed C-C Cross-Coupling of 1-(Aryl)methoxy-1H-benzotriazoles with Arylboronic Acids. Cheminform. 47. DOI: 10.1002/CHIN.201617099 |
0.534 |
|
2015 |
Yedulla VR, Pradhan P, Yang L, Lakshman MK. Cycloaddition of Arynes and Cyclic Enol Ethers as a Platform for Access to Stereochemically Defined 1,2-Disubstituted Benzocyclobutenes. European Journal of Organic Chemistry. 2015: 750-764. PMID 27642260 DOI: 10.1002/Ejoc.201403250 |
0.448 |
|
2015 |
Singh MK, Lakshman MK. Diarylmethanes through an Unprecedented Palladium-Catalyzed C-C Cross-Coupling of 1-(Aryl)methoxy-1 H-Benzotriazoles with Arylboronic Acids. Chemcatchem. 7: 4156-4162. PMID 27134687 DOI: 10.1002/Cctc.201500818 |
0.662 |
|
2015 |
Satishkumar S, Vuram PK, Relangi SS, Gurram V, Zhou H, Kreitman RJ, Montemayor MM, Yang L, Kaliyaperumal M, Sharma S, Pottabathini N, Lakshman MK. Cladribine Analogues via O⁶-(Benzotriazolyl) Derivatives of Guanine Nucleosides. Molecules (Basel, Switzerland). 20: 18437-18463. PMID 26556315 DOI: 10.3390/Molecules201018437 |
0.316 |
|
2015 |
Thomson PF, Parrish D, Pradhan P, Lakshman MK. Modular, Metal-Catalyzed Cycloisomerization Approach to Angularly Fused Polycyclic Aromatic Hydrocarbons and Their Oxidized Derivatives. The Journal of Organic Chemistry. 80: 7435-46. PMID 26196673 DOI: 10.1021/Acs.Joc.5B00931 |
0.717 |
|
2015 |
Gurram V, Akula HK, Garlapati R, Pottabathini N, Lakshman MK. Mild and General Access to Diverse 1H-Benzotriazoles via Diboron-Mediated N-OH Deoxygenation and Palladium-Catalyzed C-C and C-N Bond Formation. Advanced Synthesis & Catalysis. 357: 451-462. PMID 25729343 DOI: 10.1002/Adsc.201400889 |
0.509 |
|
2015 |
Yedulla VR, Pradhan P, Yang L, Lakshman MK. Cycloaddition of arynes and cyclic enol ethers as a platform for access to stereochemically defined 1,2-disubstituted benzocyclobutenes European Journal of Organic Chemistry. 2015: 750-764. DOI: 10.1002/ejoc.201403250 |
0.344 |
|
2015 |
Singh MK, Lakshman MK. Diarylmethanes through an Unprecedented Palladium-Catalyzed C-C Cross-Coupling of 1-(Aryl)methoxy-1 H-Benzotriazoles with Arylboronic Acids Chemcatchem. 7: 4156-4162. DOI: 10.1002/cctc.201500818 |
0.529 |
|
2014 |
Lakshman MK, Singh MK, Kumar M, Chamala RR, Yedulla VR, Wagner D, Leung E, Yang L, Matin A, Ahmad S. Facile synthesis of 1-alkoxy-1H-benzo- and 7-azabenzotriazoles from peptide coupling agents, mechanistic studies, and synthetic applications. Beilstein Journal of Organic Chemistry. 10: 1919-32. PMID 25246951 DOI: 10.3762/Bjoc.10.200 |
0.608 |
|
2013 |
Chamala RR, Parrish D, Pradhan P, Lakshman MK. Purinyl N1-directed aromatic C-H oxidation in 6-arylpurines and 6-arylpurine nucleosides. The Journal of Organic Chemistry. 78: 7423-35. PMID 23844876 DOI: 10.1021/Jo4008282 |
0.511 |
|
2013 |
Gurram V, Pottabathini N, Garlapati R, Chaudhary AB, Patro B, Lakshman MK. ChemInform Abstract: C-C Cross-Coupling Reactions of O6-Alkyl-2-haloinosine Derivatives and a One-Pot Cross-Coupling/O6-Deprotection Procedure. Cheminform. 44: no-no. DOI: 10.1002/CHIN.201302175 |
0.308 |
|
2012 |
Akula HK, Lakshman MK. Synthesis of deuterated 1,2,3-triazoles. The Journal of Organic Chemistry. 77: 8896-904. PMID 23016757 DOI: 10.1021/Jo301146J |
0.392 |
|
2012 |
Lakshman MK, Kumar A, Balachandran R, Day BW, Andrei G, Snoeck R, Balzarini J. Synthesis and biological properties of C-2 triazolylinosine derivatives. The Journal of Organic Chemistry. 77: 5870-83. PMID 22758929 DOI: 10.1021/Jo300628Y |
0.542 |
|
2012 |
Kokatla HP, Lakshman MK. Two-step, one-pot synthesis of inosine, guanosine, and 2'-deoxyguanosine O6-ethers via intermediate O6-(benzotriazol-1-yl) derivatives. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit1.26. PMID 22700333 DOI: 10.1002/0471142700.Nc0126S49 |
0.759 |
|
2012 |
Gurram V, Pottabathini N, Garlapati R, Chaudhary AB, Patro B, Lakshman MK. C-C cross-coupling reactions of O6-alkyl-2-haloinosine derivatives and a one-pot cross-coupling/O6-deprotection procedure. Chemistry, An Asian Journal. 7: 1853-61. PMID 22570232 DOI: 10.1002/Asia.201200093 |
0.452 |
|
2012 |
Gurram V, Pottabathini N, Garlapati R, Chaudhary AB, Patro B, Lakshman MK. Cover Picture: CC Cross‐Coupling Reactions of
O
6
‐Alkyl‐2‐Haloinosine Derivatives and a One‐Pot Cross‐Coupling/
O
6
‐Deprotection Procedure (Chem. Asian J. 8/2012) Chemistry – An Asian Journal. 7: 1725-1725. DOI: 10.1002/Asia.201290030 |
0.346 |
|
2011 |
Lakshman MK, Deb AC, Chamala RR, Pradhan P, Pratap R. Direct arylation of 6-phenylpurine and 6-arylpurine nucleosides by ruthenium-catalyzed C-H bond activation. Angewandte Chemie (International Ed. in English). 50: 11400-4. PMID 21956882 DOI: 10.1002/Anie.201104035 |
0.4 |
|
2011 |
Kokatla HP, Thomson PF, Bae S, Doddi VR, Lakshman MK. Reduction of amine N-oxides by diboron reagents. The Journal of Organic Chemistry. 76: 7842-8. PMID 21812467 DOI: 10.1021/Jo201192C |
0.76 |
|
2011 |
Lakshman MK, Deb AC, Chamala RR, Pradhan P, Pratap R. Inside Cover: Direct Arylation of 6-Phenylpurine and 6-Arylpurine Nucleosides by Ruthenium-Catalyzed CH Bond Activation (Angew. Chem. Int. Ed. 48/2011) Angewandte Chemie International Edition. 50: 11264-11264. DOI: 10.1002/Anie.201106047 |
0.356 |
|
2011 |
Lakshman MK, Deb AC, Chamala RR, Pradhan P, Pratap R. Innentitelbild: Direct Arylation of 6-Phenylpurine and 6-Arylpurine Nucleosides by Ruthenium-Catalyzed CH Bond Activation (Angew. Chem. 48/2011) Angewandte Chemie. 123: 11460-11460. DOI: 10.1002/Ange.201106047 |
0.367 |
|
2011 |
Lagisetty P, Zhang L, Lakshman MK. Corrigendum: Simple Methodology for Heck Arylation at C-8 of Adenine Nucleosides Advanced Synthesis & Catalysis. 353: 183-183. DOI: 10.1002/Adsc.201190004 |
0.408 |
|
2010 |
Kumar A, Akula HK, Lakshman MK. Simple Synthesis of Amides and Weinreb Amides via Use of PPh3 or Polymer-Supported PPh3 and Iodine. European Journal of Organic Chemistry. 2010. PMID 24223494 DOI: 10.1002/Ejoc.200901420 |
0.421 |
|
2010 |
Thomson PF, Lagisetty P, Balzarini J, De Clercq E, Lakshman MK. Palladium-Catalyzed Aryl Amination Reactions of 6-Bromo- and 6-Chloropurine Nucleosides. Advanced Synthesis & Catalysis. 352: 1728-1735. PMID 21818182 DOI: 10.1002/Adsc.200900728 |
0.713 |
|
2010 |
Kokatla HP, Lakshman MK. One-pot etherification of purine nucleosides and pyrimidines. Organic Letters. 12: 4478-81. PMID 20845979 DOI: 10.1021/Ol101655H |
0.756 |
|
2010 |
Lakshman MK, Singh MK, Parrish D, Balachandran R, Day BW. Azide-tetrazole equilibrium of C-6 azidopurine nucleosides and their ligation reactions with alkynes. The Journal of Organic Chemistry. 75: 2461-73. PMID 20297785 DOI: 10.1021/Jo902342Z |
0.614 |
|
2010 |
Thomson PF, Lagisetty P, Balzarini J, De Clercq E, Lakshman MK. ChemInform Abstract: Palladium-Catalyzed Aryl Amination Reactions of 6-Bromo- and 6-Chloropurine Nucleosides. Cheminform. 41: no-no. DOI: 10.1002/CHIN.201051203 |
0.665 |
|
2010 |
Lakshman MK, Keeler JC, Hilmer JH, Martin JW. ChemInform Abstract: Palladium-Catalyzed C-N Bond Formation: Facile and General Synthesis of N6-Aryl 2′-Deoxyadenosine Analogues. Cheminform. 30: no-no. DOI: 10.1002/chin.199940194 |
0.386 |
|
2009 |
Lakshman MK, Choudhury A, Bae S, Rochttis E, Pradhan P, Kumar A. Synthesis of N (6) ,N (6)-Dialkyl Adenine Nucleosides With In Situ Formed Hexaalkylphosphorus Triamides. European Journal of Organic Chemistry. 2009: 152-159. PMID 23930082 DOI: 10.1002/Ejoc.200800752 |
0.541 |
|
2009 |
Pratap R, Parrish D, Gunda P, Venkataraman D, Lakshman MK. Influence of biaryl phosphine structure on C-N and C-C bond formation. Journal of the American Chemical Society. 131: 12240-9. PMID 19655743 DOI: 10.1021/Ja902679B |
0.792 |
|
2009 |
Lakshman MK, Frank J. A simple method for C-6 modification of guanine nucleosides. Organic & Biomolecular Chemistry. 7: 2933-40. PMID 19582304 DOI: 10.1039/B905298D |
0.477 |
|
2009 |
Bae S, Chaturvedi S, Lakshman MK. O6-(benzotriazol-1-yl)inosine derivatives for C6 modification of purine nucleosides. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 1.22. PMID 19319856 DOI: 10.1002/0471142700.Nc0122S36 |
0.47 |
|
2009 |
Singh MK, Lakshman MK. A simple synthesis of nitriles from aldoximes. The Journal of Organic Chemistry. 74: 3079-84. PMID 19301882 DOI: 10.1021/Jo900100V |
0.624 |
|
2008 |
Bae S, Lakshman MK. Synthetic utility of an isolable nucleoside phosphonium salt. Organic Letters. 10: 2203-6. PMID 18476663 DOI: 10.1021/Ol8006106 |
0.495 |
|
2008 |
Bae S, Lakshman MK. A novel polymer supported approach to nucleoside modification. The Journal of Organic Chemistry. 73: 3707-13. PMID 18429630 DOI: 10.1021/Jo702558N |
0.316 |
|
2008 |
Bae S, Lakshman MK. Unusual deoxygenation and reactivity studies related to O6-(benzotriazol-1-yl)inosine derivatives. The Journal of Organic Chemistry. 73: 1311-9. PMID 18205381 DOI: 10.1021/Jo7021795 |
0.485 |
|
2008 |
Lagisetty P, Zhang L, Lakshman MK. ChemInform Abstract: Simple Methodology for Heck Arylation at C-8 of Adenine Nucleosides. Cheminform. 39. DOI: 10.1002/CHIN.200829190 |
0.304 |
|
2008 |
Lagisetty P, Zhang L, Lakshman M. Simple Methodology for Heck Arylation at C-8 of Adenine Nucleosides Advanced Synthesis & Catalysis. 350: 602-608. DOI: 10.1002/Adsc.200700418 |
0.508 |
|
2007 |
Bae S, Mah H, Chaturvedi S, Jeknic TM, Baird WM, Katz AK, Carrell HL, Glusker JP, Okazaki T, Laali KK, Zajc B, Lakshman MK. Synthetic, crystallographic, computational, and biological studies of 1,4-difluorobenzo[c]phenanthrene and its metabolites. The Journal of Organic Chemistry. 72: 7625-33. PMID 17764198 DOI: 10.1021/Jo071145S |
0.371 |
|
2007 |
Kang SB, De Clercq E, Lakshman MK. Pd-catalyzed C-C bond-forming reactions of thymidine mesitylene sulfonate. The Journal of Organic Chemistry. 72: 5724-30. PMID 17595142 DOI: 10.1021/Jo070843+ |
0.53 |
|
2007 |
Champeil E, Pradhan P, Lakshman MK. Palladium-catalyzed synthesis of nucleoside adducts from bay- and fjord-region diol epoxides. The Journal of Organic Chemistry. 72: 5035-45. PMID 17559269 DOI: 10.1021/Jo070204Z |
0.499 |
|
2007 |
Brulé C, Laali KK, Okazaki T, Lakshman MK. Structure/reactivity relationships in the benzo[c]phenanthrene skeleton: stable ion and electrophilic substitution (nitration, bromination) study of substituted analogues, novel carbocations and substituted derivatives. The Journal of Organic Chemistry. 72: 3232-41. PMID 17394355 DOI: 10.1021/Jo0625453 |
0.414 |
|
2007 |
Bae S, Lakshman MK. O6-(benzotriazol-1-yl)inosine derivatives: easily synthesized, reactive nucleosides. Journal of the American Chemical Society. 129: 782-9. PMID 17243813 DOI: 10.1021/Ja064682N |
0.457 |
|
2007 |
Lakshman MK, Keeler JC, Ngassa FN, Hilmer JH, Pradhan P, Zajc B, Thomasson KA. Highly diastereoselective synthesis of nucleoside adducts from the carcinogenic benzo[a]pyrene diol epoxide and a computational analysis. Journal of the American Chemical Society. 129: 68-76. PMID 17199284 DOI: 10.1021/Ja063902U |
0.393 |
|
2007 |
Kang SB, Clercq ED, Lakshman MK. Pd-Catalyzed Synthesis of C4-Aryl Pyrimidinone Nucleoside Analogues Synfacts. 2007: 1036-1036. DOI: 10.1055/S-2007-968982 |
0.44 |
|
2006 |
Ngassa FN, Dekorver KA, Melistas TS, Yeh EA, Lakshman MK. Pd-Xantphos-catalyzed direct arylation of nucleosides. Organic Letters. 8: 4613-6. PMID 16986963 DOI: 10.1021/Ol0619516 |
0.461 |
|
2006 |
Lagisetty P, Russon LM, Lakshman MK. A general synthesis of C6-azolyl purine nucleosides. Angewandte Chemie (International Ed. in English). 45: 3660-3. PMID 16639768 DOI: 10.1002/Anie.200504565 |
0.396 |
|
2005 |
Lakshman MK, Gunda P, Pradhan P. Mild and room temperature C-C bond forming reactions of nucleoside C-6 arylsulfonates. The Journal of Organic Chemistry. 70: 10329-35. PMID 16323841 DOI: 10.1021/Jo0513764 |
0.789 |
|
2005 |
Pottabathini N, Bae S, Pradhan P, Hahn HG, Mah H, Lakshman MK. Synthesis and reactions of 2-chloro- and 2-tosyloxy-2'-deoxyinosine derivatives. The Journal of Organic Chemistry. 70: 7188-95. PMID 16122237 DOI: 10.1021/Jo050847J |
0.538 |
|
2005 |
Lakshman MK. Synthesis of biologically important nucleoside analogs by palladium-catalyzed C-N bond-formation Current Organic Synthesis. 2: 83-112. DOI: 10.2174/1570179052996955 |
0.522 |
|
2004 |
Gunda P, Russon LM, Lakshman MK. Pd-catalyzed amination of nucleoside arylsulfonates to yield N6-aryl-2,6-diaminopurine nucleosides. Angewandte Chemie (International Ed. in English). 43: 6372-7. PMID 15558680 DOI: 10.1002/Anie.200460782 |
0.773 |
|
2003 |
Okazaki T, Laali KK, Zajc B, Lakshman MK, Kumar S, Baird WM, Dashwood WM. Stable ion study of benzo[a]pyrene (BaP) derivatives: 7,8-dihydro-BaP, 9,10-dihydro-BaP and its 6-halo derivatives, 1- and 3-methoxy-9,10-dihydro-BaP-7(8H)-one, as well as the proximate carcinogen BaP 7,8-dihydrodiol and its dibenzoate, combined with a comparative DNA binding study of regioisomeric (1-, 4-, 2-) pyrenylcarbinols. Organic & Biomolecular Chemistry. 1: 1509-16. PMID 12926280 DOI: 10.1039/B212412B |
0.371 |
|
2003 |
Lakshman MK, Ngassa FN, Bae S, Buchanan DG, Hahn HG, Mah H. Synthesis of pyrene and benzo[a]pyrene adducts at the exocyclic amino groups of 2'-deoxyadenosine and 2'-deoxyguanosine by a palladium-mediated C-N bond-formation strategy. The Journal of Organic Chemistry. 68: 6020-30. PMID 12868942 DOI: 10.1021/Jo030113B |
0.515 |
|
2003 |
Zajc B, Grahek R, Kocijan A, Lakshman MK, Kosmrlj J, Lah J. Evaluation of the enantiomeric resolution of 7,8-dihydroxy-7,8-dihydrobenzo[a]-pyrene and its 6-fluoro and 6-bromo derivatives on polysaccharide-derived stationary phases. The Journal of Organic Chemistry. 68: 3291-4. PMID 12688804 DOI: 10.1021/Jo020607T |
0.308 |
|
2003 |
Lakshman MK, Gunda P. Palladium-catalyzed synthesis of carcinogenic polycyclic aromatic hydrocarbon epoxide-nucleoside adducts: the first amination of a chloro nucleoside. Organic Letters. 5: 39-42. PMID 12509885 DOI: 10.1021/Ol027084W |
0.814 |
|
2002 |
Lakshman MK, Thomson PF, Nuqui MA, Hilmer JH, Sevova N, Boggess B. Facile Pd-catalyzed cross-coupling of 2'-deoxyguanosine O6-arylsulfonates with arylboronic acids. Organic Letters. 4: 1479-82. PMID 11975608 DOI: 10.1021/Ol025673W |
0.669 |
|
2002 |
Lakshman MK. Palladium-catalyzed C-N and C-C cross-couplings as versatile, new avenues for modifications of purine 2′-deoxynucleosides Journal of Organometallic Chemistry. 653: 234-251. DOI: 10.1016/S0022-328X(02)01267-6 |
0.477 |
|
2001 |
Lakshman MK, Hilmer JH, Martin JQ, Keeler JC, Dinh YQ, Ngassa FN, Russon LM. Palladium catalysis for the synthesis of hydrophobic C-6 and C-2 aryl 2'-deoxynucleosides. Comparison of C-C versus C-N bond formation as well as C-6 versus C-2 reactivity. Journal of the American Chemical Society. 123: 7779-87. PMID 11493051 DOI: 10.1021/Ja0107172 |
0.473 |
|
2000 |
Lakshman MK, Ngassa FN, Keeler JC, Dinh YQ, Hilmer JH, Russon LM. Facile synthesis of O6-alkyl-, O6-aryl-, and diaminopurine nucleosides from 2'-deoxyguanosine Organic Letters. 2: 927-30. PMID 10768188 DOI: 10.1021/Ol005564M |
0.371 |
|
2000 |
Lakshman MK, Kole PL, Chaturvedi S, Saugier JH, Yeh HJC, Glusker JP, Carrell HL, Katz AK, Afshar CE, Dashwood WM, Kenniston G, Baird WM. Methyl group-induced helicity in 1,4-dimethylbenzo[c]phenanthrene and its metabolites: Synthesis, physical, and biological properties Journal of the American Chemical Society. 122: 12629-12636. DOI: 10.1021/Ja002072W |
0.444 |
|
1999 |
Lakshman MK, Keeler JC, Hilmer JH, Martin JQ. Palladium-catalyzed C-N bond formation: Facile and general synthesis of N6-aryl 2'-deoxyadenosine analogues Journal of the American Chemical Society. 121: 6090-6091. DOI: 10.1021/Ja9908671 |
0.474 |
|
1998 |
Page JE, Zajc B, Oh-hara T, Lakshman MK, Sayer JM, Jerina DM, Dipple A. Sequence context profoundly influences the mutagenic potency of trans- opened benzo[a]pyrene 7,8-diol 9,10-epoxide - Purine nucleoside adducts in site-specific mutation studies Biochemistry. 37: 9127-9137. PMID 9636059 DOI: 10.1021/Bi980273V |
0.451 |
|
1997 |
Lakshman MK, Chaturvedi S, Kole PL, Windels JH, Myers MB, Brown MA. Resolution of polycyclic aromatic hydrocarbon dihydrodiols via diastereomeric formaldehyde acetals Tetrahedron Asymmetry. 8: 3375-3378. DOI: 10.1016/S0957-4166(97)00464-3 |
0.409 |
|
1996 |
Chaturvedi S, Lakshman MK. Site-specific modification of the human N-ras proto-oncogene with each diol epoxide metabolite of benzo[a]pyrene and thermal denaturation studies of the adducted duplexes Carcinogenesis. 17: 2747-2752. PMID 9006115 DOI: 10.1093/Carcin/17.12.2747 |
0.451 |
|
1996 |
Page JE, Christner DF, Lakshman MK, Zajc B, Oh-Hara T, Lipinski LJ, Ross HL, Agarwal R, Szeliga J, Yagi H, Sayer JM, Jerina DM, Dipple A. Effects of polycyclic aromatic hydrocarbon adducts with deoxyguanosine and deoxyadenosine in vivo and in vitro Polycyclic Aromatic Compounds. 10: 171-178. DOI: 10.1080/10406639608034694 |
0.517 |
|
1996 |
Lakshman MK, Zajc B. A rapid, high-yield method for 5′-hydroxyl protection in very reactive and amino group modified nucleosides using dimethoxytrityl tetrafluoroborate Nucleosides and Nucleotides. 15: 1029-1039. DOI: 10.1080/07328319608002032 |
0.417 |
|
1996 |
Lakshman MK, Zajc B. Regio and stereocontrolled synthesis of aryl cis aminoalcohols from cis glycols Tetrahedron Letters. 37: 2529-2532. DOI: 10.1016/0040-4039(96)00334-6 |
0.376 |
|
1995 |
Schurter EJ, Yeh HJ, Sayer JM, Lakshman MK, Yagi H, Jerina DM, Gorenstein DG. NMR solution structure of a nonanucleotide duplex with a dG mismatch opposite a 10R adduct derived from trans addition of a deoxyadenosine N6-amino group to (-)-(7S,8R,9R,10S)-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene. Biochemistry. 34: 1364-75. PMID 7827084 DOI: 10.1021/Bi00004A031 |
0.499 |
|
1995 |
Lebreton PR, Huang CR, Fernando H, Zajc B, Lakshman MK, Sayer JM, Jerina DM. Multiple fluorescence lifetimes for oligonucleotides containing single, site-specific modifications at guanine and adenine corresponding to trans addition of exocyclic amino groups to (+)-(7R,8S,9S,10R)- and (-)-(7S,8R,9R,10S)-7,8-Dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene Chemical Research in Toxicology. 8: 338-348. PMID 7578919 DOI: 10.1021/Tx00045A004 |
0.485 |
|
1995 |
Yeh HJ, Sayer JM, Liu X, Altieri AS, Byrd RA, Lakshman MK, Yagi H, Schurter EJ, Gorenstein DG, Jerina DM. NMR solution structure of a nonanucleotide duplex with a dG mismatch opposite a 10S adduct derived from trans addition of a deoxyadenosine N6-amino group to (+)-(7R,8S,9S,10R)-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene: an unusual syn glycosidic torsion angle at the modified dA. Biochemistry. 34: 13570-81. PMID 7577946 DOI: 10.1021/Bi00041A037 |
0.537 |
|
1995 |
Zajc B, Lakshman MK. Acyl migration in anions derived from nonenolizable esters of polycyclic aromatic hydrocarbons The Journal of Organic Chemistry. 60: 4936-4939. DOI: 10.1021/Jo00120A047 |
0.386 |
|
1995 |
LAKSHMAN MK, LEHR RE. ChemInform Abstract: Synthesis of 1,2-Epoxy-1,2,3,4-tetrahydrobenzo(g)chrysene: The First Synthesis of a Fjord-Region Tetrahydroepoxide. Cheminform. 26: no-no. DOI: 10.1002/chin.199516137 |
0.624 |
|
1994 |
Christner DF, Lakshman MK, Sayer JM, Jerina DM, Dipple A. Primer extension by various polymerases using oligonucleotide templates containing stereoisomeric benzo[a]pyrene - deoxyadenosine adducts Biochemistry. 33: 14297-14305. PMID 7524675 DOI: 10.1021/Bi00251A043 |
0.531 |
|
1994 |
Lakshman MK, Chaturvedi S, Lehr RE. Improved high-yield synthesis of polycyclic aromatic hydrocarbon amino tribenzoates, nucleophilic components for synthesis of diol epoxide-nucleoside adducts Synthetic Communications. 24: 2983-2988. DOI: 10.1080/00397919408010618 |
0.696 |
|
1994 |
Lakshman MK, Lehr RE. Synthesis of 1,2-epoxy-1,2,3,4-tetrahydro-benzofe]chrysene: The first synthesis of a fjord-region tetrahydroepoxide Synthetic Communications. 24: 2973-2981. DOI: 10.1080/00397919408010617 |
0.658 |
|
1994 |
Lakshman MK, Xiao W, Sayer JM, Cheh AM, Jerina DM. Synthesis and assignment of absolute configuration to the N6-deoxyadenosine adducts resulting from cis and trans ring-opening of phenanthrene 9,10-oxide Journal of Organic Chemistry. 59: 1755-1760. DOI: 10.1021/Jo00086A027 |
0.56 |
|
1992 |
Lakshman MK, Lehr RE. Solvent dependent changes in the proton nmr spectra of 2’ -deoxyadenosine and its derivatives Nucleosides and Nucleotides. 11: 1039-1046. DOI: 10.1080/07328319208021166 |
0.644 |
|
1992 |
Lakshman MK, Sayer JM, Yagi H, Jerina DM. Synthesis and duplex-forming properties of a nonanucleotide containing an N6-deoxyadenosine adduct of a bay-region diol epoxide Journal of Organic Chemistry. 57: 4585-4590. DOI: 10.1021/Jo00043A012 |
0.49 |
|
1992 |
Lakshman MK, Sayer JM, Jerina DM. Synthesis and site-specific incorporation of a bay-region cis ring-opened tetrahydro epoxide-deoxyadenosine adduct into a DNA oligomer Journal of Organic Chemistry. 57: 3438-3443. DOI: 10.1021/Jo00038A037 |
0.593 |
|
1992 |
Zajc B, Lakshman MK, Sayer JM, Jerina DM. Epoxide and diol epoxide adducts of polycyclic aromatic hydrocarbons at the exocyclic amino group of deoxyguanosine Tetrahedron Letters. 33: 3409-3412. DOI: 10.1016/S0040-4039(00)92649-2 |
0.586 |
|
1992 |
Lakshman MK, Yeh HJC, Yagi H, Jerina DM. Synthesis of deoxyadenosine adducts from the highly carcinogenic fjord region diol epoxide of benzo[c]phenanthrene Tetrahedron Letters. 33: 7121-7124. DOI: 10.1016/S0040-4039(00)60852-3 |
0.592 |
|
1991 |
Lakshman MK, Sayer JM, Jerina DM. Chemical synthesis of a bay-region polycyclic aromatic hydrocarbon tetrahydroepoxide-deoxyadenosine adduct and its site-specific incorporation into a DNA oligomer Journal of the American Chemical Society. 113: 6589-6594. DOI: 10.1021/Ja00017A034 |
0.498 |
|
1990 |
LAKSHMAN M, LEHR RE. ChemInform Abstract: Synthesis of Polycyclic Aromatic Hydrocarbon-Substituted 2′-Deoxyadenosine Analogs. Cheminform. 21. DOI: 10.1002/chin.199049299 |
0.669 |
|
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