| Year |
Citation |
Score |
| 2020 |
Saha S, Kiran M, Kuscu C, Chatrath A, Wotton D, Mayo MW, Dutta A. Long noncoding RNA DRAIC inhibits prostate cancer progression by interacting with IKK to inhibit NF-κB activation. Cancer Research. PMID 31900260 DOI: 10.1158/0008-5472.Can-19-3460 |
0.312 |
|
| 2019 |
Shah A, Melhuish TA, Fox TE, Frierson HF, Wotton D. TGIF transcription factors repress acetyl CoA metabolic gene expression and promote intestinal tumor growth. Genes & Development. PMID 30808659 DOI: 10.1101/Gad.320127.118 |
0.395 |
|
| 2018 |
Melhuish TA, Kowalczyk I, Manukyan A, Zhang Y, Shah A, Abounader R, Wotton D. Myt1 and Myt1l transcription factors limit proliferation in GBM cells by repressing YAP1 expression. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. PMID 30312684 DOI: 10.1016/J.Bbagrm.2018.10.005 |
0.369 |
|
| 2018 |
Parini P, Melhuish TA, Wotton D, Larsson L, Ahmed O, Eriksson M, Pramfalk C. Overexpression of transforming growth factor β induced factor homeobox 1 represses NPC1L1 and lowers markers of intestinal cholesterol absorption. Atherosclerosis. 275: 246-255. PMID 29980051 DOI: 10.1016/J.Atherosclerosis.2018.06.867 |
0.345 |
|
| 2018 |
Hao Y, Bjerke GA, Pietrzak K, Melhuish TA, Han Y, Turner SD, Frierson HF, Wotton D. TGFβ signaling limits lineage plasticity in prostate cancer. Plos Genetics. 14: e1007409. PMID 29782499 DOI: 10.1371/Journal.Pgen.1007409 |
0.337 |
|
| 2018 |
Wotton D, Taniguchi K. Functions of TGIF homeodomain proteins and their roles in normal brain development and holoprosencephaly. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. PMID 29749689 DOI: 10.1002/Ajmg.C.31612 |
0.64 |
|
| 2018 |
Manukyan A, Kowalczyk I, Melhuish TA, Lemiesz A, Wotton D. Analysis of transcriptional activity by the Myt1 and Myt1l transcription factors. Journal of Cellular Biochemistry. PMID 29291346 DOI: 10.1002/Jcb.26636 |
0.412 |
|
| 2017 |
Yang CS, Melhuish TA, Spencer A, Ni L, Hao Y, Jividen K, Harris TE, Snow C, Frierson HF, Wotton D, Paschal BM. The protein kinase C super-family member PKN is regulated by mTOR and influences differentiation during prostate cancer progression. The Prostate. PMID 28875501 DOI: 10.1002/Pros.23400 |
0.353 |
|
| 2017 |
Wotton D, Pemberton LF, Merrill-Schools J. SUMO and Chromatin Remodeling. Advances in Experimental Medicine and Biology. 963: 35-50. PMID 28197905 DOI: 10.1007/978-3-319-50044-7_3 |
0.373 |
|
| 2016 |
Anderson AE, Taniguchi K, Hao Y, Melhuish TA, Shah A, Turner SD, Sutherland AE, Wotton D. Tgif1 and Tgif2 repress expression of the RabGAP, Evi5l. Molecular and Cellular Biology. PMID 27956704 DOI: 10.1128/Mcb.00527-16 |
0.628 |
|
| 2016 |
Taniguchi K, Anderson AE, Melhuish TA, Carlton AL, Manukyan A, Sutherland AE, Wotton D. Genetic and Molecular Analyses indicate independent effects of TGIFs on Nodal and Gli3 in neural tube patterning. European Journal of Human Genetics : Ejhg. PMID 27924807 DOI: 10.1038/Ejhg.2016.164 |
0.63 |
|
| 2016 |
Melhuish TA, Taniguchi K, Wotton D. Tgif1 and Tgif2 Regulate Axial Patterning in Mouse. Plos One. 11: e0155837. PMID 27187787 DOI: 10.1371/Journal.Pone.0155837 |
0.623 |
|
| 2014 |
Wotton D. A CREB1-TGFβ2 self-sustaining loop in glioblastoma. Cancer Discovery. 4: 1123-5. PMID 25274684 DOI: 10.1158/2159-8290.Cd-14-0861 |
0.329 |
|
| 2014 |
Bjerke GA, Pietrzak K, Melhuish TA, Frierson HF, Paschal BM, Wotton D. Prostate cancer induced by loss of Apc is restrained by TGFβ signaling. Plos One. 9: e92800. PMID 24651496 DOI: 10.1371/Journal.Pone.0092800 |
0.328 |
|
| 2014 |
Pramfalk C, Melhuish TA, Wotton D, Jiang ZY, Eriksson M, Parini P. TG-interacting factor 1 acts as a transcriptional repressor of sterol O-acyltransferase 2. Journal of Lipid Research. 55: 709-17. PMID 24478032 DOI: 10.1194/Jlr.M045922 |
0.311 |
|
| 2014 |
Bjerke GA, Yang CS, Frierson HF, Paschal BM, Wotton D. Activation of Akt signaling in prostate induces a TGFβ-mediated restraint on cancer progression and metastasis. Oncogene. 33: 3660-7. PMID 23995785 DOI: 10.1038/Onc.2013.342 |
0.36 |
|
| 2013 |
Yan L, Womack B, Wotton D, Guo Y, Shyr Y, Davé U, Li C, Hiebert S, Brandt S, Hamid R. Tgif1 regulates quiescence and self-renewal of hematopoietic stem cells. Molecular and Cellular Biology. 33: 4824-33. PMID 24100014 DOI: 10.1128/Mcb.01076-13 |
0.322 |
|
| 2012 |
Wotton D. TGF-β drives DNA demethylation. Molecular Cell. 46: 556-7. PMID 22681884 DOI: 10.1016/J.Molcel.2012.05.031 |
0.301 |
|
| 2012 |
Zerlanko BJ, Bartholin L, Melhuish TA, Wotton D. Premature senescence and increased TGFβ signaling in the absence of Tgif1. Plos One. 7: e35460. PMID 22514746 DOI: 10.1371/Journal.Pone.0035460 |
0.754 |
|
| 2012 |
Taniguchi K, Anderson AE, Sutherland AE, Wotton D. Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway. Plos Genetics. 8: e1002524. PMID 22383895 DOI: 10.1371/Journal.Pgen.1002524 |
0.636 |
|
| 2011 |
Bjerke GA, Hyman-Walsh C, Wotton D. Cooperative transcriptional activation by Klf4, Meis2, and Pbx1. Molecular and Cellular Biology. 31: 3723-33. PMID 21746878 DOI: 10.1128/Mcb.01456-10 |
0.415 |
|
| 2010 |
Quijano JC, Stinchfield MJ, Zerlanko B, Gibbens YY, Takaesu NT, Hyman-Walsh C, Wotton D, Newfeld SJ. The Sno oncogene antagonizes Wingless signaling during wing development in Drosophila. Plos One. 5: e11619. PMID 20661280 DOI: 10.1371/Journal.Pone.0011619 |
0.767 |
|
| 2010 |
Vincent DF, Kaniewski B, Powers SE, Havenar-Daughton C, Marie JC, Wotton D, Bartholin L. A rapid strategy to detect the recombined allele in LSL-TβRICA transgenic mice. Genesis (New York, N.Y. : 2000). 48: 559-62. PMID 20645310 DOI: 10.1002/Dvg.20653 |
0.602 |
|
| 2010 |
Hyman-Walsh C, Bjerke GA, Wotton D. An autoinhibitory effect of the homothorax domain of Meis2. The Febs Journal. 277: 2584-97. PMID 20553494 DOI: 10.1111/J.1742-464X.2010.07668.X |
0.332 |
|
| 2010 |
Melhuish TA, Chung DD, Bjerke GA, Wotton D. Tgif1 represses apolipoprotein gene expression in liver. Journal of Cellular Biochemistry. 111: 380-90. PMID 20506222 DOI: 10.1002/Jcb.22713 |
0.386 |
|
| 2010 |
Merrill JC, Kagey MH, Melhuish TA, Powers SE, Zerlanko BJ, Wotton D. Inhibition of CtBP1 activity by Akt-mediated phosphorylation. Journal of Molecular Biology. 398: 657-71. PMID 20361981 DOI: 10.1016/J.Jmb.2010.03.048 |
0.696 |
|
| 2010 |
Merrill JC, Melhuish TA, Kagey MH, Yang SH, Sharrocks AD, Wotton D. A role for non-covalent SUMO interaction motifs in Pc2/CBX4 E3 activity. Plos One. 5: e8794. PMID 20098713 DOI: 10.1371/Journal.Pone.0008794 |
0.718 |
|
| 2010 |
Powers SE, Taniguchi K, Yen W, Melhuish TA, Shen J, Walsh CA, Sutherland AE, Wotton D. Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation. Development (Cambridge, England). 137: 249-59. PMID 20040491 DOI: 10.1242/Dev.040782 |
0.734 |
|
| 2009 |
Taniguchi K, Powers SE, Wotton D. The role of Tgif and Tgif2 during head development Developmental Biology. 331: 525. DOI: 10.1016/J.Ydbio.2009.05.516 |
0.647 |
|
| 2008 |
Bartholin L, Melhuish TA, Powers SE, Goddard-Léon S, Treilleux I, Sutherland AE, Wotton D. Maternal Tgif is required for vascularization of the embryonic placenta. Developmental Biology. 319: 285-97. PMID 18508043 DOI: 10.1016/J.Ydbio.2008.04.027 |
0.63 |
|
| 2007 |
Wotton D, Merrill JC. Pc2 and SUMOylation Biochemical Society Transactions. 35: 1401-1404. PMID 18031231 DOI: 10.1042/Bst0351401 |
0.399 |
|
| 2007 |
Chung DD, Honda K, Cafuir L, McDuffie M, Wotton D. The Runx3 distal transcript encodes an additional transcriptional activation domain. The Febs Journal. 274: 3429-39. PMID 17555522 DOI: 10.1111/J.1742-4658.2007.05875.X |
0.35 |
|
| 2007 |
El-Jaick KB, Powers SE, Bartholin L, Myers KR, Hahn J, Orioli IM, Ouspenskaia M, Lacbawan F, Roessler E, Wotton D, Muenke M. Functional analysis of mutations in TGIF associated with holoprosencephaly. Molecular Genetics and Metabolism. 90: 97-111. PMID 16962354 DOI: 10.1016/J.Ymgme.2006.07.011 |
0.615 |
|
| 2006 |
Takaesu NT, Hyman-Walsh C, Ye Y, Wisotzkey RG, Stinchfield MJ, O'connor MB, Wotton D, Newfeld SJ. dSno facilitates baboon signaling in the Drosophila brain by switching the affinity of Medea away from Mad and toward dSmad2. Genetics. 174: 1299-313. PMID 16951053 DOI: 10.1534/Genetics.106.064956 |
0.418 |
|
| 2006 |
Melhuish TA, Wotton D. The Tgif2 gene contains a retained intron within the coding sequence. Bmc Molecular Biology. 7: 2. PMID 16436215 DOI: 10.1186/1471-2199-7-2 |
0.39 |
|
| 2006 |
Bartholin L, Powers SE, Melhuish TA, Lasse S, Weinstein M, Wotton D. TGIF inhibits retinoid signaling. Molecular and Cellular Biology. 26: 990-1001. PMID 16428452 DOI: 10.1128/Mcb.26.3.990-1001.2006 |
0.675 |
|
| 2005 |
Massagué J, Seoane J, Wotton D. Smad transcription factors. Genes & Development. 19: 2783-810. PMID 16322555 DOI: 10.1101/Gad.1350705 |
0.392 |
|
| 2005 |
Kagey MH, Melhuish TA, Powers SE, Wotton D. Multiple activities contribute to Pc2 E3 function. The Embo Journal. 24: 108-19. PMID 15592428 DOI: 10.1038/Sj.Emboj.7600506 |
0.743 |
|
| 2003 |
Hyman CA, Bartholin L, Newfeld SJ, Wotton D. Drosophila TGIF proteins are transcriptional activators. Molecular and Cellular Biology. 23: 9262-74. PMID 14645536 DOI: 10.1128/Mcb.23.24.9262-9274.2003 |
0.425 |
|
| 2003 |
Kagey MH, Melhuish TA, Wotton D. The polycomb protein Pc2 is a SUMO E3. Cell. 113: 127-37. PMID 12679040 DOI: 10.1016/S0092-8674(03)00159-4 |
0.722 |
|
| 2001 |
Wotton D, Knoepfler PS, Laherty CD, Eisenman RN, Massagué J. The Smad transcriptional corepressor TGIF recruits mSin3. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 12: 457-63. PMID 11571228 |
0.311 |
|
| 2001 |
Melhuish TA, Gallo CM, Wotton D. TGIF2 Interacts with Histone Deacetylase I and Represses Transcription Journal of Biological Chemistry. 276: 32109-32114. PMID 11427533 DOI: 10.1074/Jbc.M103377200 |
0.414 |
|
| 2001 |
Lo RS, Wotton D, Massagué J. Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF Embo Journal. 20: 128-136. PMID 11226163 DOI: 10.1093/Emboj/20.1.128 |
0.399 |
|
| 2001 |
Wotton D, Massagué J. Smad Transcriptional Corepressors in TGFβ Family Signaling Current Topics in Microbiology and Immunology. 254: 145-164. DOI: 10.1007/978-3-662-10595-5_8 |
0.338 |
|
| 2000 |
Wotton D, Massague J. Smad transcriptional corepressors in TGFβ family signaling Current Topics in Microbiology and Immunology. 254: 145-164. PMID 11190572 |
0.346 |
|
| 2000 |
Melhuish TA, Wotton D. The interaction of the carboxyl terminus-binding protein with the Smad corepressor TGIF is disrupted by a holoprosencephaly mutation in TGIF Journal of Biological Chemistry. 275: 39762-39766. PMID 10995736 DOI: 10.1074/Jbc.C000416200 |
0.419 |
|
| 2000 |
Gripp KW, Wotton D, Edwards MC, Roessler E, Ades L, Meinecke P, Richieri-Costa A, Zackai EH, Massagué J, Muenke M, Elledge SJ. Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination Nature Genetics. 25: 205-208. PMID 10835638 DOI: 10.1038/76074 |
0.434 |
|
| 2000 |
Massagué J, Wotton D. Transcriptional control by the TGF-β/Smad signaling system Embo Journal. 19: 1745-1754. PMID 10775259 DOI: 10.1093/Emboj/19.8.1745 |
0.359 |
|
| 1999 |
Wotton D, Lo RS, Swaby LAC, Massagué J. Multiple modes of repression by the Smad transcriptional corepressor TGIF Journal of Biological Chemistry. 274: 37105-37110. PMID 10601270 DOI: 10.1074/Jbc.274.52.37105 |
0.387 |
|
| 1999 |
Wotton D, Lo RS, Lee S, Massagué J. A Smad transcriptional corepressor Cell. 97: 29-39. PMID 10199400 DOI: 10.1016/S0092-8674(00)80712-6 |
0.379 |
|
| 1998 |
Chen YG, Hata A, Lo RS, Wotton D, Shi Y, Pavletich N, Massagué J. Determinants of specificity in TGF-β signal transduction Genes and Development. 12: 2144-2152. PMID 9679059 DOI: 10.1101/Gad.12.14.2144 |
0.384 |
|
| 1997 |
Hata A, Lo RS, Wotton D, Lagna G, Massagué J. Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4 Nature. 388: 82-87. PMID 9214507 DOI: 10.1038/40424 |
0.359 |
|
| 1997 |
Wotton D, Shore D. A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae Genes and Development. 11: 748-760. PMID 9087429 DOI: 10.1101/Gad.11.6.748 |
0.401 |
|
| 1996 |
Wotton D, Freeman K, Shore D. Multimerization of Hsp42p, a novel heat shock protein of Saccharomyces cerevisiae, is dependent on a conserved carboxyl-terminal sequence Journal of Biological Chemistry. 271: 2717-2723. PMID 8576246 DOI: 10.1074/Jbc.271.5.2717 |
0.359 |
|
| 1995 |
Wotton D, Higgins JA, O'Hehir RE, Lamb JR, Lake RA. Differential induction of the NF-AT complex during restimulation and the induction of T-cell anergy Human Immunology. 42: 95-102. PMID 7744623 DOI: 10.1016/0198-8859(94)00004-A |
0.34 |
|
| 1995 |
Wotton D, Lake RA, Farr CJ, Owen MJ. The high mobility group transcription factor, SOX4, transactivates the human CD2 enhancer Journal of Biological Chemistry. 270: 7515-7522. PMID 7706298 DOI: 10.1074/Jbc.270.13.7515 |
0.336 |
|
| 1992 |
Prosser HM, Wotton D, Gegonne A, Ghysdael J, Wang S, Speck NA, Owen MJ. A phorbol ester response element within the human T-cell receptor β-chain enhancer Proceedings of the National Academy of Sciences of the United States of America. 89: 9934-9938. PMID 1409722 DOI: 10.1073/Pnas.89.20.9934 |
0.375 |
|
| 1991 |
Prosser HM, Lake RA, Wotton D, Owen MJ. Identification and functional analysis of the transcriptional enhancer of the human T cell receptor β gene European Journal of Immunology. 21: 161-166. PMID 1825057 DOI: 10.1002/Eji.1830210124 |
0.38 |
|
| 1990 |
Lake RA, Wotton D, Owen MJ. A 3′ transcriptional enhancer regulates tissue-specific expression of the human CD2 gene Embo Journal. 9: 3129-3136. PMID 2209539 DOI: 10.1002/J.1460-2075.1990.Tb07510.X |
0.34 |
|
| 1990 |
Flanagan BF, Wotton D, Tuck-Wah S, Owen MJ. DNase hypersensitivity and methylation of the human CD3G and D genes during T-cell development Immunogenetics. 31: 13-20. PMID 2137107 DOI: 10.1007/Bf00702484 |
0.336 |
|
| 1989 |
Wotton D, Flanagan BF, Owen MJ. Chromatin configuration of the human CD2 gene locus during T-cell development Proceedings of the National Academy of Sciences of the United States of America. 86: 4195-4199. PMID 2567000 DOI: 10.1073/Pnas.86.11.4195 |
0.329 |
|
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