David M. Bodine - Publications

Affiliations: 
Biochemistry & Molecular Georgetown University, Washington, DC 
Area:
Genetics, Molecular Biology, Biochemistry

195 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Psaila B, Wang G, Rodriguez-Meira A, Li R, Heuston EF, Murphy L, Yee D, Hitchcock IS, Sousos N, O'Sullivan J, Anderson S, Senis YA, Weinberg OK, Calicchio ML, ... ... Bodine DM, et al. Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets. Molecular Cell. 78: 477-492.e8. PMID 32386542 DOI: 10.1016/J.Molcel.2020.04.008  0.452
2020 Xiang G, Keller CA, Heuston EF, Giardine BM, An L, Wixom AQ, Miller A, Cockburn A, Sauria MEG, Weaver K, Lichtenberg J, Göttgens B, Li Q, Bodine D, Mahony S, et al. An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis. Genome Research. PMID 32132109 DOI: 10.1101/Gr.255760.119  0.382
2019 Hardison RC, Zhang Y, Keller CA, Xiang G, Heuston EF, An L, Lichtenberg J, Giardine BM, Bodine D, Mahony S, Li Q, Yue F, Weiss MJ, Blobel GA, Taylor J, et al. Systematic integration of GATA transcription factors and epigenomes via IDEAS paints the regulatory landscape of hematopoietic cells. Iubmb Life. PMID 31769130 DOI: 10.1002/Iub.2195  0.47
2019 Bodine DM. The long and the short of it. Blood. 134: 1565-1566. PMID 31698422 DOI: 10.1182/Blood.2019002983  0.318
2019 Bodine DM. All hands on DEK. The Journal of Clinical Investigation. 130: 2205-2206. PMID 31107244 DOI: 10.1172/Jci128986  0.374
2019 Goodell MA, Bodine DM. Single-cell technology meets hematology: introduction to a review series. Blood. PMID 30728147 DOI: 10.1182/Blood-2019-01-887224  0.354
2019 Bodine DM, Lichtenberg J, Seidel N, SequencingProgram NC, Jagadeesh GJ, Conboy JG, Farrar JE, Kang J, Blanc L, Atsidaftos E, Ellis S, Lipton JMM, Vlachos A. Whole Genome Sequencing Identifies Small Deletions in Ribosomal Genes Causing Diamond Blackfan Anemia Blood. 134: 2502-2502. DOI: 10.1182/Blood-2019-121710  0.4
2019 Simmons WR, Li Q, Hausman JA, Zheng S, Eaton W, Low PS, Bodine DM. Hemoglobin S Polymerization Can be Inhibited By Alterations in Erythrocyte Glycolysis Blood. 134: 977-977. DOI: 10.1182/Blood-2019-121709  0.374
2019 Heuston EF, Psaila B, Keller CA, SequencingProgram NC, Anderson SM, Kirby M, Murphy LC, Wixom AQ, Giardine B, Hardison RC, Bodine DM. Mouse Erythroid Cells Originate from a Megakaryocyte Precursor in Common Myeloid Progenitors Blood. 134: 337-337. DOI: 10.1182/Blood-2019-121631  0.362
2018 Heuston EF, Keller CA, Lichtenberg J, Giardine B, Anderson SM, Hardison RC, Bodine DM. Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points. Epigenetics & Chromatin. 11: 22. PMID 29807547 DOI: 10.1186/S13072-018-0195-Z  0.401
2018 Farrar JE, Kang J, Seidel N, Lichtenberg J, Atsidaftos E, Lipton JM, Vlachos A, Bodine DM. Altered Epigenetic Maturation in Early Erythroid Cells from Diamond Blackfan Anemia Patients Treated with Transfusions, Corticosteroids, or in Remission Blood. 132: 752-752. DOI: 10.1182/Blood-2018-99-116994  0.398
2018 Heuston EF, Psaila B, Anderson SM, Sequencing Program NC, Bodine DM. Single Cell RNASeq Demonstrates That Mouse Erythroid Cells Are the Last Lineage to Emerge Blood. 132: 1274-1274. DOI: 10.1182/Blood-2018-99-110318  0.439
2017 Park S, Han CR, Park JW, Zhao L, Zhu X, Willingham M, Bodine DM, Cheng SY. Defective erythropoiesis caused by mutations of the thyroid hormone receptor α gene. Plos Genetics. 13: e1006991. PMID 28910278 DOI: 10.1371/Journal.Pgen.1006991  0.455
2017 Lichtenberg J, Elnitski L, Bodine DM. SigSeeker: a peak-calling ensemble approach for constructing epigenetic signatures. Bioinformatics (Oxford, England). PMID 28449120 DOI: 10.1093/Bioinformatics/Btx276  0.313
2017 O'Brien KA, Farrar JE, Vlachos A, Anderson SM, Tsujiura CA, Lichtenberg J, Blanc L, Atsidaftos E, Elkahloun A, An X, Ellis SR, Lipton JM, Bodine DM. Molecular convergence in ex vivo models of Diamond Blackfan anemia. Blood. PMID 28377399 DOI: 10.1182/Blood-2017-01-760462  0.412
2017 Bodine DM. Introduction to a review series on Transcription Factors in Hematopoiesis and Hematologic Disease. Blood. PMID 28179277 DOI: 10.1182/Blood-2017-02-766840  0.346
2017 Psaila B, Heuston EF, Milojkovic D, Lichtenberg J, Anderson SM, Hoffman R, Roberts I, Mead AJ, Bodine DM, Program NCS, Barkas N. A Single-Cell Approach to Unraveling Abnormal Megakaryocyte Differentiation and Function in Myelofibrosis Blood. 130: 490-490. DOI: 10.1182/Blood.V130.Suppl_1.490.490  0.416
2017 Lichtenberg J, Farrar JE, Chelimo D, Horne F, Program NCS, Ellis S, Vlachos A, Lipton JH, Bodine DM. Whole Genome Sequencing to Detect Small Deletions in Ribosomal Protein Genes in Diamond Blackfan Anemia Patients Blood. 130: 1174-1174. DOI: 10.1182/Blood.V130.Suppl_1.1174.1174  0.315
2017 Loya AJ, Cincotta DJ, Elkahloun A, Bodine D, Rice KP. Abstract 2109: Transcriptional analysis of human leukemia cells treated with the experimental anticancer drug laromustine Cancer Research. 77: 2109-2109. DOI: 10.1158/1538-7445.Am2017-2109  0.413
2016 Psaila B, Barkas N, Iskander D, Roy A, Anderson S, Ashley N, Caputo VS, Lichtenberg J, Loaiza S, Bodine DM, Karadimitris A, Mead AJ, Roberts I. Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways. Genome Biology. 17: 83. PMID 27142433 DOI: 10.1186/S13059-016-0939-7  0.396
2016 Lichtenberg J, Heuston EF, Anderson SM, Sequencing Center NI, Keller CA, Hardison RC, Bodine DM. De Novo DNA Methylation Is Associated with Granulopoiesis and Megakaryopoiesis but Not Erythropoiesis Blood. 128: 3868-3868. DOI: 10.1182/Blood.V128.22.3868.3868  0.351
2016 Heuston EF, Keller CA, Lichtenberg J, Anderson SM, Sequencing Center NI, Hardison RC, Bodine DM. Establishment of Enhancer Elements during Erythro-Megakaryopoiesis Blood. 128: 1486-1486. DOI: 10.1182/Blood.V128.22.1486.1486  0.456
2015 Lichtenberg J, Heuston EF, Mishra T, Keller CA, Hardison RC, Bodine DM. SBR-Blood: systems biology repository for hematopoietic cells. Nucleic Acids Research. PMID 26590403 DOI: 10.1093/Nar/Gkv1263  0.419
2015 Glait-Santar C, Desmond R, Feng X, Bat T, Chen J, Heuston E, Mizukawa B, Mulloy JC, Bodine DM, Larochelle A, Dunbar CE. Functional Niche Competition Between Normal Hematopoietic Stem and Progenitor Cells and Myeloid Leukemia Cells. Stem Cells (Dayton, Ohio). PMID 26388434 DOI: 10.1002/Stem.2208  0.394
2015 Lee M, Beggs SM, Gildea D, Bupp S, Lichtenberg J, Trivedi NS, Hu Y, Bodine DM, Crawford NP. Necdin is a breast cancer metastasis suppressor that regulates the transcription of c-Myc. Oncotarget. PMID 26384308 DOI: 10.18632/Oncotarget.5230  0.383
2015 O'Brien K, Vlachos A, Anderson SM, Tsujiura C, Blanc L, Atsidaftos E, Sequencing Center NI, Farrar JE, Ellis SR, Lipton JM, Bodine DM. Transcriptome Analysis of Erythroid Cells Cultured from Diamond Blackfan Anemia Patients with Ribosomal and GATA1 Mutations Reveals Dysregulation of Inflammatory Response Genes Blood. 126: 3605-3605. DOI: 10.1182/Blood.V126.23.3605.3605  0.414
2015 Heuston EF, Keller CA, Anderson SM, Sequencing Center NI, Hardison RC, Bodine DM. Enhancer Accessibility during Erythropoiesis and Megakaryopoiesis Correlates with Lineage-Specific Gene Expression Blood. 126: 3576-3576. DOI: 10.1182/Blood.V126.23.3576.3576  0.448
2015 Lichtenberg J, Heuston EF, Keller CA, Hardison RC, Bodine DM. Comparison of Expression and Epigenetic Profiles in Human and Mouse Erythropoiesis and Megakaryopoiesis Using a Systems Biology Model Blood. 126: 2383-2383. DOI: 10.1182/Blood.V126.23.2383.2383  0.461
2014 Lee M, Dworkin AM, Lichtenberg J, Patel SJ, Trivedi NS, Gildea D, Bodine DM, Crawford NP. Metastasis-associated protein ribosomal RNA processing 1 homolog B (RRP1B) modulates metastasis through regulation of histone methylation. Molecular Cancer Research : McR. 12: 1818-28. PMID 25092915 DOI: 10.1158/1541-7786.Mcr-14-0167  0.407
2014 Farrar JE, Quarello P, Fisher R, O'Brien KA, Aspesi A, Parrella S, Henson AL, Seidel NE, Atsidaftos E, Prakash S, Bari S, Garelli E, Arceci RJ, Dianzani I, Ramenghi U, ... ... Bodine DM, et al. Exploiting pre-rRNA processing in Diamond Blackfan anemia gene discovery and diagnosis. American Journal of Hematology. 89: 985-91. PMID 25042156 DOI: 10.1002/Ajh.23807  0.352
2014 Paralkar VR, Mishra T, Luan J, Yao Y, Kossenkov AV, Anderson SM, Dunagin M, Pimkin M, Gore M, Sun D, Konuthula N, Raj A, An X, Mohandas N, Bodine DM, et al. Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development. Blood. 123: 1927-37. PMID 24497530 DOI: 10.1182/Blood-2013-12-544494  0.34
2014 O'Brien KA, Anderson SM, Farrar J, Vlachos A, Atsidaftos E, Lipton JM, Ellis SR, Bodine DM. In Vitro Analysis of Erythroid Cells Derived from the Culture of Diamond Blackfan Anemia Patient CD34+ Cells Blood. 124: 744-744. DOI: 10.1182/Blood.V124.21.744.744  0.422
2014 Lee M, Dworkin AM, Lichtenberg J, Patel SJ, Gildea D, Bodine DM, Crawford NP. Abstract 123: The breast cancer metastasis suppressor RRP1B modulates metastasis through regulation of histone methylation Cancer Research. 74: 123-123. DOI: 10.1158/1538-7445.Am2014-123  0.419
2013 Seidel NE, Farrar J, Vlachos A, Program NCS, Anderson SM, An X, Atsidaftos E, Malech H, Arceci RJ, Ellis SR, Lipton JM, Bodine DM. Autosomal Recessive Diamond-Blackfan Anemia: Identification Of Mutations In MCM2 and Flnb Blood. 122: 589-589. DOI: 10.1182/Blood.V122.21.589.589  0.43
2013 Paralkar VR, Mishra T, Luan J, Yao Y, Kossenkov A, Konuthula N, An X, Narla M, Bodine DM, Hardison RC, Weiss MJ. Species-Specific Functions For Long Noncoding RNAs During Erythropoeisis Blood. 122: 2441-2441. DOI: 10.1182/Blood.V122.21.2441.2441  0.382
2013 Heuston EF, Lichtenberg J, Anderson SM, Paralkar VR, Capone CK, Hardison RC, Weiss MJ, Bodine DM. Differences In The Genome-Wide Epigenetic Signatures Of mRNA and Long Non-Coding RNA Genes In Mouse Erythroblasts and Megakaryocytes Blood. 122: 1198-1198. DOI: 10.1182/Blood.V122.21.1198.1198  0.421
2013 Lee M, Beggs SM, Lichtenberg J, Bupp SB, Trivedi NS, Hu Y, Bodine DM, Crawford NPS. Abstract C21: A germline polymorphism in Necdin causes changes in gene expression and mammary tumor metastasis Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-C21  0.416
2012 Yocum AO, Steiner LA, Seidel NE, Cline AP, Rout ED, Lin JY, Wong C, Garrett LJ, Gallagher PG, Bodine DM. A tissue-specific chromatin loop activates the erythroid ankyrin-1 promoter. Blood. 120: 3586-93. PMID 22968456 DOI: 10.1182/Blood-2012-08-450262  0.764
2012 Punwani D, Simon K, Choi Y, Dutra A, Gonzalez-Espinosa D, Pak E, Naradikian M, Song CH, Zhang J, Bodine DM, Puck JM. Transcription factor zinc finger and BTB domain 1 is essential for lymphocyte development. Journal of Immunology (Baltimore, Md. : 1950). 189: 1253-64. PMID 22753936 DOI: 10.4049/Jimmunol.1200623  0.436
2012 Hogart A, Lichtenberg J, Ajay SS, Anderson S, Margulies EH, Bodine DM. Genome-wide DNA methylation profiles in hematopoietic stem and progenitor cells reveal overrepresentation of ETS transcription factor binding sites. Genome Research. 22: 1407-18. PMID 22684279 DOI: 10.1101/Gr.132878.111  0.352
2012 Fisher R, Henson A, Quarello P, Aspesi A, Farrar JE, Arceci RJ, Bodine DM, Dianzani I, Lipton JM, Ramenghi U, Vlachos A, Ellis SR. Insights Into Diagnosis and Etiology of Diamond Blackfan Anemia by Analysis of Pre-rRNA Processing Blood. 120: 3476-3476. DOI: 10.1182/Blood.V120.21.3476.3476  0.372
2012 Paralkar VR, Mishra T, Luan J, Yao Y, Konuthula N, Bodine DM, Hardison RC, Weiss MJ. Long Noncoding RNAs in Erythropoiesis and Megakaryopoiesis. Blood. 120: 2331-2331. DOI: 10.1182/Blood.V120.21.2331.2331  0.393
2011 Farrar JE, Vlachos A, Atsidaftos E, Carlson-Donohoe H, Markello TC, Arceci RJ, Ellis SR, Lipton JM, Bodine DM. Ribosomal protein gene deletions in Diamond-Blackfan anemia. Blood. 118: 6943-51. PMID 22045982 DOI: 10.1182/Blood-2011-08-375170  0.375
2011 Pilon AM, Ajay SS, Kumar SA, Steiner LA, Cherukuri PF, Wincovitch S, Anderson SM, Mullikin JC, Gallagher PG, Hardison RC, Margulies EH, Bodine DM. Genome-wide ChIP-Seq reveals a dramatic shift in the binding of the transcription factor erythroid Kruppel-like factor during erythrocyte differentiation. Blood. 118: e139-48. PMID 21900194 DOI: 10.1182/Blood-2011-05-355107  0.409
2011 Yang MQ, Laflamme K, Gotea V, Joiner CH, Seidel NE, Wong C, Petrykowska HM, Lichtenberg J, Lee S, Welch L, Gallagher PG, Bodine DM, Elnitski L. Genome-wide detection of a TFIID localization element from an initial human disease mutation. Nucleic Acids Research. 39: 2175-87. PMID 21071415 DOI: 10.1093/Nar/Gkq1035  0.381
2011 Steiner LA, Schulz V, Maksimova Y, Seidel NE, Bodine DM, Gallagher PG. Unbiased Identification of Functional Barrier Insulators in Primary Human Erythroid Cells, Blood. 118: 3385-3385. DOI: 10.1182/Blood.V118.21.3385.3385  0.426
2011 Hogart A, Lichtenberg J, Ajay S, Margulies E, Bodine DM. Genome-Wide DNA Methylation Profiling of Hematopoietic Stem and Progenitor Cells Reveals Over-Representation of ETS Transcrition Factor Binding Sites Blood. 118: 211-211. DOI: 10.1182/Blood.V118.21.211.211  0.385
2010 Gallagher PG, Steiner LA, Liem RI, Owen AN, Cline AP, Seidel NE, Garrett LJ, Bodine DM. Mutation of a barrier insulator in the human ankyrin-1 gene is associated with hereditary spherocytosis. The Journal of Clinical Investigation. 120: 4453-65. PMID 21099109 DOI: 10.1172/Jci42240  0.471
2010 Devlin EE, Dacosta L, Mohandas N, Elliott G, Bodine DM. A transgenic mouse model demonstrates a dominant negative effect of a point mutation in the RPS19 gene associated with Diamond-Blackfan anemia. Blood. 116: 2826-35. PMID 20606162 DOI: 10.1182/Blood-2010-03-275776  0.364
2010 Laflamme K, Owen AN, Devlin EE, Yang MQ, Wong C, Steiner LA, Garrett LJ, Elnitski L, Gallagher PG, Bodine DM. Functional analysis of a novel cis-acting regulatory region within the human ankyrin gene (ANK-1) promoter. Molecular and Cellular Biology. 30: 3493-502. PMID 20479128 DOI: 10.1128/Mcb.00119-10  0.416
2010 Vlachos A, Farrar J, Atsidaftos E, Muir E, Markello TC, Singh S, Liu JM, Ellis S, Arceci RJ, Bodine DM, Lipton JM. 5q- Myelodysplastic Syndrome, In One of 23 Children Lacking a Known Ribosomal Gene Mutation, Masquerading as Diamond Blackfan Anemia (DBA) and Responding to Lenalidomide Blood. 116: LBA-2-LBA-2. DOI: 10.1182/Blood.V116.21.Lba-2.Lba-2  0.342
2010 Steiner LA, Schulz VP, Maksimova Y, Mahajan M, Bodine DM, Gallagher PG. Dynamic CO-Localization of GATA1, NFE2, and EKLF and Changes in Gene Expression During Hematopoiesis Blood. 116: 741-741. DOI: 10.1182/Blood.V116.21.741.741  0.42
2010 Vlachos A, Farrar J, Atsidaftos E, Muir E, Markello TC, Singh S, Liu JM, Ellis S, Arceci RJ, Bodine DM, Lipton JM. 5q- Syndrome In a Child: Is This Acquired Diamond Blackfan Anemia (DBA)? Blood. 116: 4430-4430. DOI: 10.1182/Blood.V116.21.4430.4430  0.312
2010 Owen AN, Steiner LA, Gallagher PG, Bodine DM. An Active Chromatin Hub Involving the Three Alternate Promoter/First Exons of the Ankyrin-1 (ANK-1) Gene Blood. 116: 3862-3862. DOI: 10.1182/Blood.V116.21.3862.3862  0.426
2010 Farrar JE, Vlachos A, Atsidaftos E, Carlson-Donohoe H, Ellis SR, Markello TC, Arceci RJ, Lipton JM, Bodine DM. SNP Array Genotyping Reveals Constitutional and Mosaic Losses of Ribosomal Protein Gene Regions In Patients with Diamond Blackfan Anemia without Ribosomal Protein Gene Mutations. Blood. 116: 1168-1168. DOI: 10.1182/Blood.V116.21.1168.1168  0.368
2009 da Cunha AF, Brugnerotto AF, Corat MA, Devlin EE, Gimenes AP, de Melo MB, Passos LA, Bodine D, Saad ST, Costa FF. High levels of human gamma-globin are expressed in adult mice carrying a transgene of the Brazilian type of hereditary persistence of fetal hemoglobin ((A)gamma -195). Hemoglobin. 33: 439-47. PMID 19958189 DOI: 10.3109/03630260903344176  0.347
2009 Nemeth MJ, Mak KK, Yang Y, Bodine DM. beta-Catenin expression in the bone marrow microenvironment is required for long-term maintenance of primitive hematopoietic cells. Stem Cells (Dayton, Ohio). 27: 1109-19. PMID 19415781 DOI: 10.1002/Stem.32  0.37
2009 Gallagher PG, Nilson DG, Steiner LA, Maksimova YD, Lin JY, Bodine DM. An insulator with barrier-element activity promotes alpha-spectrin gene expression in erythroid cells. Blood. 113: 1547-54. PMID 19008453 DOI: 10.1182/Blood-2008-06-164954  0.442
2009 Pilon AM, Ajay SS, Abaan HO, Margulies EH, Gallagher PG, Bodine DM. Genome-Wide ChIP-Seq Reveals a Dramatic Shift in the EKLF Binding Profile Between Erythroid Progenitors and Erythroblasts. Blood. 114: 565-565. DOI: 10.1182/Blood.V114.22.565.565  0.456
2009 Hogart A, Ajay SS, Abaan HO, Anderson SM, Margulies EH, Bodine DM. Genome-Wide DNA Methylation Patterns Reveal Specific Signatures for HSC, CMP and Erythroblasts. Blood. 114: 391-391. DOI: 10.1182/Blood.V114.22.391.391  0.439
2009 Harrow FJ, Cline AP, Seidel NE, Persons D, Gallagher PG, Bodine DM. A Modified ANK-1 Promoter Directs Uniform, Copy Number Dependent Gamma Globin Gene Expression at Therapeutic Levels of a in a Lentivirus Vector. Blood. 114: 3565-3565. DOI: 10.1182/Blood.V114.22.3565.3565  0.463
2008 Pilon AM, Arcasoy MO, Dressman HK, Vayda SE, Maksimova YD, Sangerman JI, Gallagher PG, Bodine DM. Failure of terminal erythroid differentiation in EKLF-deficient mice is associated with cell cycle perturbation and reduced expression of E2F2. Molecular and Cellular Biology. 28: 7394-401. PMID 18852285 DOI: 10.1128/Mcb.01087-08  0.476
2008 Zoueva OP, Garrett LJ, Bodine D, Rodgers GP. BP1 motif in the human beta-globin promoter affects beta-globin expression during embryonic/fetal erythropoiesis in transgenic mice bearing the human beta-globin gene. Blood Cells, Molecules & Diseases. 41: 244-51. PMID 18656399 DOI: 10.1016/J.Bcmd.2008.05.008  0.36
2008 Ryu BY, Evans-Galea MV, Gray JT, Bodine DM, Persons DA, Nienhuis AW. An experimental system for the evaluation of retroviral vector design to diminish the risk for proto-oncogene activation. Blood. 111: 1866-75. PMID 17991809 DOI: 10.1182/Blood-2007-04-085506  0.406
2008 Devlin EE, DaCosta L, Narla M, Elliott G, Bodine DM. A Mouse Model for Diamond-Blackfan Anemia Demonstrates a Dominant Negative Effect of a Point Mutation in the RPS19 Gene Blood. 112: 38-38. DOI: 10.1182/Blood.V112.11.38.38  0.477
2008 Steiner LA, Maksimova Y, Lin J, Owen AN, Schulz V, Bodine DM, Gallagher PG. Insulator Elements in Erythrocyte Membrane Genes Blood. 112: 3584-3584. DOI: 10.1182/Blood.V112.11.3584.3584  0.421
2008 Pilon AM, Margulies EH, Abaan HO, Allen AW, Townes TM, Frederick AM, Zhou D, Gallagher PG, Bodine DM. Genome-Wide Analysis of EKLF Occupancy in Erythroid Chromatin Reveals 5′, 3′ and Intragenic Binding Sites in EKLF Target Genes Blood. 112: 283-283. DOI: 10.1182/Blood.V112.11.283.283  0.365
2008 Owen AN, Laflamme K, Pilon AM, Garrett LJ, Gallagher PG, Bodine DM. Local and Distant Elements Regulate Tissue-Specific Expression of ANK-1 Gene Transcripts Blood. 112: 2432-2432. DOI: 10.1182/Blood.V112.11.2432.2432  0.454
2007 Nemeth MJ, Topol L, Anderson SM, Yang Y, Bodine DM. Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation. Proceedings of the National Academy of Sciences of the United States of America. 104: 15436-41. PMID 17881570 DOI: 10.1073/Pnas.0704747104  0.347
2007 Nemeth MJ, Bodine DM. Regulation of hematopoiesis and the hematopoietic stem cell niche by Wnt signaling pathways. Cell Research. 17: 746-58. PMID 17768401 DOI: 10.1038/Cr.2007.69  0.343
2007 Xi H, Shulha HP, Lin JM, Vales TR, Fu Y, Bodine DM, McKay RD, Chenoweth JG, Tesar PJ, Furey TS, Ren B, Weng Z, Crawford GE. Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome. Plos Genetics. 3: e136. PMID 17708682 DOI: 10.1371/Journal.Pgen.0030136  0.302
2007 Nemeth M, Yang Y, Bodine D. β-Catenin Expression in Bone Marrow Stromal Cells Is Required for Normal Proliferation and Differentiation of Primitive Hematopoietic Cells. Blood. 110: 608-608. DOI: 10.1182/Blood.V110.11.608.608  0.355
2007 Cunha AF, Brugnerotto AF, Melo MB, Corat MA, Gimenes AP, Passos LA, Devlin EE, Bodine DM, Saad ST, Costa FF. Expression of High Levels of Human γ-Globin in Adult Mice Carrying a Transgene of the Brazilian Type of Hereditary Persistence of Fetal Hemoglobin. Blood. 110: 3831-3831. DOI: 10.1182/Blood.V110.11.3831.3831  0.428
2007 Laflamme K, Elnitski LE, Wong C, Mary Y, Gallagher PG, Bodine DM. Identification of a TFIID Binding Sequence That Increases Expression from the Ankyrin-1 Promoter: Application to Globin Gene Therapy Blood. 110: 3741-3741. DOI: 10.1182/Blood.V110.11.3741.3741  0.467
2007 Harrow F, Battle S, Seidel NE, Cline AP, Gallagher PG, Bodine DM. Characterization of Regulatory Elements in the Slc4a1 (Band 3) Locus To Create Safe and Effective Vectors for Globin Gene Therapy Blood. 110: 3740-3740. DOI: 10.1182/Blood.V110.11.3740.3740  0.47
2007 Steiner LA, Lin JY, Owens AN, Sangerman JI, Bodine DM, Gallagher PG. Alternate Promoters Direct Tissue-Specific Expression of Erythrocyte Ankyrin Transcripts with Novel NH2-Termini. Blood. 110: 1710-1710. DOI: 10.1182/Blood.V110.11.1710.1710  0.408
2007 Pilon AM, Beaupre J, Bieker JJ, Gallagher PG, Bodine DM. Multiple Defects of Both Primitive and Definitive Erythrocytes in EKLF-Deficient Mice. Blood. 110: 1234-1234. DOI: 10.1182/Blood.V110.11.1234.1234  0.349
2007 Bodine DM. Dendritic cells reach out in different directions Blood. 110: 2783. DOI: 10.1182/Blood-2007-07-099770  0.345
2007 Ryu BY, Gray JT, Bodine DM, Nienhuis AW. Activation of the LMO2 gene in human lymphoid cells by targeted insertion of a single retroviral LTR expression cassette into the first intron Blood Cells, Molecules, and Diseases. 38: 176. DOI: 10.1016/J.Bcmd.2006.10.126  0.433
2006 Nemeth MJ, Kirby MR, Bodine DM. Hmgb3 regulates the balance between hematopoietic stem cell self-renewal and differentiation. Proceedings of the National Academy of Sciences of the United States of America. 103: 13783-8. PMID 16945912 DOI: 10.1073/Pnas.0604006103  0.375
2006 Nilson DG, Sabatino DE, Bodine DM, Gallagher PG. Major erythrocyte membrane protein genes in EKLF-deficient mice. Experimental Hematology. 34: 705-12. PMID 16728274 DOI: 10.1016/J.Exphem.2006.02.018  0.409
2006 Pilon AM, Nilson DG, Zhou D, Sangerman J, Townes TM, Bodine DM, Gallagher PG. Alterations in expression and chromatin configuration of the alpha hemoglobin-stabilizing protein gene in erythroid Kruppel-like factor-deficient mice. Molecular and Cellular Biology. 26: 4368-77. PMID 16705186 DOI: 10.1128/Mcb.02216-05  0.448
2006 Nemeth M, Yang Y, Bodine D. Canonical and Non-Canonical Wnt Signaling Regulate the Balance between HSC Self-Renewal and Differentiation. Blood. 108: 862-862. DOI: 10.1182/Blood.V108.11.862.862  0.341
2006 Nemeth M, Bodine D. β-Catenin Expression in Cultured Bone Marrow Stromal Cells Is Required To Maintain Production of Osteoblasts and Hematopoietic Progenitor Cells. Blood. 108: 85-85. DOI: 10.1182/Blood.V108.11.85.85  0.38
2006 Pilon AM, Arcasoy MO, Vayda SE, Dressman HK, Bieker JJ, Bodine DM, Gallagher PG. Defects in E2F1/2 Expression Are Associated with Abnormalities in Cell Cycle and Differentiation in EKLF-Deficient Erythroid Cells. Blood. 108: 84-84. DOI: 10.1182/Blood.V108.11.84.84  0.395
2006 Owen AN, Wolfsberg T, Laflamme K, Wong C, Maksimova Y, Elnitski L, Gallagher PG, Bodine DM. A 200 kb Survey of Chromatin in the ANK-1 Locus Demonstrates an Erythroid-Specific Chromatin Hub That Activates the Erythrocyte Ankyrin (ANK-1E) Promoter. Blood. 108: 536-536. DOI: 10.1182/Blood.V108.11.536.536  0.43
2006 Devlin EE, Horton CL, Garrett-Beal LJ, Gallagher PG, Bodine DM. A Transgenic Mouse Assay To Compare the Barrier Activities of the Chicken β-Globin 5′HS4, Human β-Globin 5′HS5 and Mouse 3′HS1. Blood. 108: 362-362. DOI: 10.1182/Blood.V108.11.362.362  0.415
2006 Laflamme K, Elnitski L, Owen AN, Gallagher PG, Bodine DM. Identification of a Novel Core Promoter Element That Enhances Transcription: Application to Ankyrin Promoters for Globin Gene Therapy. Blood. 108: 3261-3261. DOI: 10.1182/Blood.V108.11.3261.3261  0.474
2006 Harrow FJ, Frazar TF, Seidel NE, Gallagher PG, Bodine DM. Lentivirus Vectors Containing a Band 3/γ-Globin Gene Flanked by Distinct Insulator Elements Are Resistant to Gene Silencing in Primary Mouse Erythroid Cells. Blood. 108: 3260-3260. DOI: 10.1182/Blood.V108.11.3260.3260  0.443
2006 Ryu BY, Gray JT, Bodine DM, Nienhuis AW. The Effect of a Chromatin Insulator (5′cHS4) on Enhanced Expression of the LMO2 Proto-Oncogene by an Oncoretroviral Long Terminal Repeat. Blood. 108: 3253-3253. DOI: 10.1182/blood.v108.11.3253.3253  0.354
2006 Sood R, Rivera L, Chahal J, Burnetti A, English M, Bodine D, Liu P. Generation of Zebrafish Lines with New Gata1 Mutations and Their Characterization with a Novel In Vitro Colony-Forming Assay. Blood. 108: 1336-1336. DOI: 10.1182/Blood.V108.11.1336.1336  0.38
2006 Ryu BY, Gray JT, Bodine DM, Nienhuis AW. 102. Activation of the LMO2 Gene in Human Lymphoid Cells by rAAV-Mediated Targeted Insertion of a Single LTR Expression Cassette into the First Intron Molecular Therapy. 13: S42. DOI: 10.1016/J.Ymthe.2006.08.122  0.452
2006 Nienhuis AW, Gray JT, Vayda S, Cline A, Evans-Galea MV, Bodine DM. 68. Evidence for Correction of Mutations in the c-Kit Gene by rAAV Mediated Gene Targeting in W/Wv Mice Molecular Therapy. 13: S29. DOI: 10.1016/J.Ymthe.2006.08.084  0.457
2005 Gallagher PG, Liem RI, Wong E, Weiss MJ, Bodine DM. GATA-1 and Oct-1 are required for expression of the human alpha-hemoglobin-stabilizing protein gene. The Journal of Biological Chemistry. 280: 39016-23. PMID 16186125 DOI: 10.1074/Jbc.M506062200  0.365
2005 Gallagher PG, Nilson DG, Wong C, Weisbein JL, Garrett-Beal LJ, Eber SW, Bodine DM. A dinucleotide deletion in the ankyrin promoter alters gene expression, transcription initiation and TFIID complex formation in hereditary spherocytosis. Human Molecular Genetics. 14: 2501-9. PMID 16037067 DOI: 10.1093/Hmg/Ddi254  0.434
2005 Lucas ML, Seidel NE, Porada CD, Quigley JG, Anderson SM, Malech HL, Abkowitz JL, Zanjani ED, Bodine DM. Improved transduction of human sheep repopulating cells by retrovirus vectors pseudotyped with feline leukemia virus type C or RD114 envelopes. Blood. 106: 51-8. PMID 15774617 DOI: 10.1182/Blood-2004-11-4491  0.396
2005 Nemeth MJ, Cline AP, Anderson SM, Garrett-Beal LJ, Bodine DM. Hmgb3 deficiency deregulates proliferation and differentiation of common lymphoid and myeloid progenitors. Blood. 105: 627-34. PMID 15358624 DOI: 10.1182/Blood-2004-07-2551  0.417
2005 Owen AN, Liem RI, Pilon AM, Gallagher PG, Bodine DM. Chromatin Conformation and a Distal Regulatory Element Activate the Human Erythroid Ankyrin-1 Promoter. Blood. 106: 803-803. DOI: 10.1182/Blood.V106.11.803.803  0.463
2005 Gallagher PG, Arcasoy MO, Vayda SE, Dressman HK, Bieker JJ, Bodine DM. A Differentiation Block in Erythroid Cells Lacking Erythroid Krupple-Like Factor (EKLF). Blood. 106: 526-526. DOI: 10.1182/Blood.V106.11.526.526  0.404
2005 Zoueva OP, Bodine D, Rodgers GP. Human Beta-Globin Expression during Erythroid Cells Development in Transgenic Mice Bearing Human Beta-Globin Gene with Mutated BP1 Binding Site. Blood. 106: 3651-3651. DOI: 10.1182/Blood.V106.11.3651.3651  0.424
2005 Dore LC, Vakoc CR, Blobel GA, Hardison RC, Bodine DM, Gallagher PG, Weiss MJ. Genomic Organization, Chromatin Structure, and Transcriptional Regulation of the Murine Alpha Hemoglobin Stabilizing Protein (AHSP) Gene. Blood. 106: 3633-3633. DOI: 10.1182/Blood.V106.11.3633.3633  0.466
2005 Nemeth M, Bodine D. Wnt5a Inhibits Wnt3a-Mediated HSC Differentiation. Blood. 106: 2271-2271. DOI: 10.1182/Blood.V106.11.2271.2271  0.316
2005 Pilon AM, Zhou D, Weiss MJ, Townes TM, Bodine DM, Gallagher PG. The Human Alpha Hemoglobin Stabilizing Protein (AHSP) Gene Locus in EKLF-Deficient Erythroid Cells. Blood. 106: 1740-1740. DOI: 10.1182/Blood.V106.11.1740.1740  0.431
2005 Nemeth M, Anderson S, Kirby M, Bodine D. Hmgb3 Regulates the Balance between HSC Differentiation and Self Renewal. Blood. 106: 1718-1718. DOI: 10.1182/Blood.V106.11.1718.1718  0.38
2005 Markham NO, Parry EM, Stefanovic M, Gallagher PG, Low PS, Bodine DM. Genetic Evidence That an 11 Amino Acid β-Hairpin Loop in the Cytoplasmic Domain of Band 3 Is Responsible for at Least 50% of Ankyrin Binding in Mouse Erythrocytes. Blood. 106: 1659-1659. DOI: 10.1182/Blood.V106.11.1659.1659  0.382
2004 Wong EY, Lin J, Forget BG, Bodine DM, Gallagher PG. Sequences downstream of the erythroid promoter are required for high level expression of the human alpha-spectrin gene. The Journal of Biological Chemistry. 279: 55024-33. PMID 15456760 DOI: 10.1074/Jbc.M408886200  0.41
2004 Pal S, Nemeth MJ, Bodine D, Miller JL, Svaren J, Thein SL, Lowry PJ, Bresnick EH. Neurokinin-B transcription in erythroid cells: direct activation by the hematopoietic transcription factor GATA-1. The Journal of Biological Chemistry. 279: 31348-56. PMID 15123623 DOI: 10.1074/Jbc.M403475200  0.387
2004 Liem RI, Cline AP, Garrett-Beal LJ, Owen AN, Gallagher PG, Bodine DM. Defining the Active Chromatin Domain of the Erythroid Ankyrin Promoter. Blood. 104: 575-575. DOI: 10.1182/Blood.V104.11.575.575  0.433
2004 Pilon AM, Wong C, Garrett-Beal LJ, Weiss M, Gallagher PG, Bodine DM. Chromatin Remodeling of the Mouse AHSP Gene Requires EKLF. Blood. 104: 375-375. DOI: 10.1182/Blood.V104.11.375.375  0.433
2004 Nemeth MJ, Anderson SM, Garrett-Beal LJ, Bodine DM. Hmgb3 Deficiency Inhibits Down-Regulation of c-kit in Hematopoietic Stem Cells. Blood. 104: 372-372. DOI: 10.1182/Blood.V104.11.372.372  0.401
2004 Gallagher PG, Pilon AM, Arcasoy MO, Bodine DM. Multiple Defects in Erythroid Gene Expression in Erythroid Krupple-Like Factor (EKLF) Target Genes in EKLF-Deficient Mice. Blood. 104: 1602-1602. DOI: 10.1182/Blood.V104.11.1602.1602  0.417
2004 Gallagher PG, Nilson DG, Lin J, Bodine DM. Sequences Downstream of the Erythroid Promoter Promote High-Level Expression of the Human α-Spectrin Gene by Providing Boundary Activity and Positive Regulatory Elements. Blood. 104: 1572-1572. DOI: 10.1182/Blood.V104.11.1572.1572  0.445
2004 Mootien S, Siedel NE, Bodine DM, Gallagher PG. 902. A novel in vivo, lentivirus-based model of |[alpha]|-spectrin function Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.808  0.442
2003 Kohn DB, Sadelain M, Dunbar C, Bodine D, Kiem HP, Candotti F, Tisdale J, Riviére I, Blau CA, Richard RE, Sorrentino B, Nolta J, Malech H, Brenner M, Cornetta K, et al. American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 180-7. PMID 12907140 DOI: 10.1016/S1525-0016(03)00212-0  0.394
2003 Frazar TF, Weisbein JL, Anderson SM, Cline AP, Garrett LJ, Felsenfeld G, Gallagher PG, Bodine DM. Variegated expression from the murine band 3 (AE1) promoter in transgenic mice is associated with mRNA transcript initiation at upstream start sites and can be suppressed by the addition of the chicken beta-globin 5' HS4 insulator element. Molecular and Cellular Biology. 23: 4753-63. PMID 12832463 DOI: 10.1128/Mcb.23.14.4753-4763.2003  0.404
2003 Brenner S, Whiting-Theobald NL, Linton GF, Holmes KL, Anderson-Cohen M, Kelly PF, Vanin EF, Pilon AM, Bodine DM, Horwitz ME, Malech HL. Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD/SCID/beta -microglobulin-/- repopulating mobilized human peripheral blood CD34+ cells. Blood. 102: 2789-97. PMID 12829597 DOI: 10.1182/Blood-2002-05-1482  0.393
2003 Nemeth MJ, Curtis DJ, Kirby MR, Garrett-Beal LJ, Seidel NE, Cline AP, Bodine DM. Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation. Blood. 102: 1298-306. PMID 12714519 DOI: 10.1182/Blood-2002-11-3541  0.467
2003 Orlic D, Kajstura J, Chimenti S, Bodine DM, Leri A, Anversa P. Bone marrow stem cells regenerate infarcted myocardium. Pediatric Transplantation. 7: 86-8. PMID 12603699 DOI: 10.1034/J.1399-3046.7.S3.13.X  0.312
2003 Broxmeyer HE, Srour EF, Hangoc G, Cooper S, Anderson SA, Bodine DM. High-efficiency recovery of functional hematopoietic progenitor and stem cells from human cord blood cryopreserved for 15 years. Proceedings of the National Academy of Sciences of the United States of America. 100: 645-50. PMID 12518050 DOI: 10.1073/Pnas.0237086100  0.392
2003 Wandersee NJ, Birkenmeier CS, Bodine DM, Mohandas N, Barker JE. Mutations in the murine erythroid alpha-spectrin gene alter spectrin mRNA and protein levels and spectrin incorporation into the red blood cell membrane skeleton. Blood. 101: 325-30. PMID 12393645 DOI: 10.1182/Blood-2002-01-0113  0.324
2003 Bodine DM. Gene therapy for sickle cell disease marches on Blood. 102: 4247-4247. DOI: 10.1182/Blood-2003-09-3305  0.346
2003 Bodine DM. Another advance for globin gene therapy Blood. 102: 416-416. DOI: 10.1182/Blood-2003-05-1516  0.305
2002 Kundu M, Chen A, Anderson S, Kirby M, Xu L, Castilla LH, Bodine D, Liu PP. Role of Cbfb in hematopoiesis and perturbations resulting from expression of the leukemogenic fusion gene Cbfb-MYH11. Blood. 100: 2449-56. PMID 12239155 DOI: 10.1182/Blood-2002-04-1064  0.463
2002 Boulanger L, Sabatino DE, Wong EY, Cline AP, Garrett LJ, Garbarz M, Dhermy D, Bodine DM, Gallagher PG. Erythroid expression of the human alpha-spectrin gene promoter is mediated by GATA-1- and NF-E2-binding proteins. The Journal of Biological Chemistry. 277: 41563-70. PMID 12196550 DOI: 10.1074/Jbc.M208184200  0.421
2002 Tsai EJ, Malech HL, Kirby MR, Hsu AP, Seidel NE, Porada CD, Zanjani ED, Bodine DM, Puck JM. Retroviral transduction of IL2RG into CD34(+) cells from X-linked severe combined immunodeficiency patients permits human T- and B-cell development in sheep chimeras. Blood. 100: 72-9. PMID 12070011 DOI: 10.1182/Blood.V100.1.72  0.409
2002 Emery DW, Bodine DM. The third conference on hematopoietic stem cell gene therapy: biology and technology. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 658-63. PMID 12027548 DOI: 10.1006/Mthe.2002.0617  0.368
2002 Licht T, Haskins M, Henthorn P, Kleiman SE, Bodine DM, Whitwam T, Puck JM, Gottesman MM, Melniczek JR. Drug selection with paclitaxel restores expression of linked IL-2 receptor gamma -chain and multidrug resistance (MDR1) transgenes in canine bone marrow. Proceedings of the National Academy of Sciences of the United States of America. 99: 3123-8. PMID 11867757 DOI: 10.1073/Pnas.052712199  0.437
2002 Bodine DM. Thalassemia gene therapy looks good at one year Blood. 99: 1883-1884. DOI: 10.1182/Blood.V99.6.1883A  0.405
2001 Nemeth MJ, Bodine DM, Garrett LJ, Lowrey CH. An erythroid-specific chromatin opening element reorganizes beta-globin promoter chromatin structure and augments gene expression. Blood Cells, Molecules & Diseases. 27: 767-80. PMID 11778661 DOI: 10.1006/Bcmd.2001.0448  0.431
2001 Curtis DJ, Dougherty L, Bodine DM. NF-Y regulates LIF-induced transcription of the signaling adaptor SKAP55R in myeloid cells. Leukemia. 15: 1932-40. PMID 11753615 DOI: 10.1038/Sj.Leu.2402286  0.433
2001 Gallagher PG, Sabatino DE, Basseres DS, Nilson DM, Wong C, Cline AP, Garrett LJ, Bodine DM. Erythrocyte Ankyrin Promoter Mutations Associated with Recessive Hereditary Spherocytosis Cause Significant Abnormalities in Ankyrin Expression Journal of Biological Chemistry. 276: 41683-41689. PMID 11527968 DOI: 10.1074/Jbc.M105844200  0.401
2001 Orlic D, Kajstura J, Chimenti S, Limana F, Jakoniuk I, Quaini F, Nadal-Ginard B, Bodine DM, Leri A, Anversa P. Mobilized bone marrow cells repair the infarcted heart, improving function and survival Proceedings of the National Academy of Sciences of the United States of America. 98: 10344-10349. PMID 11504914 DOI: 10.1073/Pnas.181177898  0.311
2001 Sabatino DE, Seidel NE, Cline AP, Anderson SM, Gallagher PG, Bodine DM. Development of a stable retrovirus vector capable of long-term expression of gamma-globin mRNA in mouse erythrocytes. Annals of the New York Academy of Sciences. 938: 246-61. PMID 11458514 DOI: 10.1111/J.1749-6632.2001.Tb03595.X  0.482
2001 Orlic D, Kajstura JAN, Chimenti S, Bodine DM, Leri A, Anversa P. Transplanted adult bone marrow cells repair myocardial infarcts in mice Annals of the New York Academy of Sciences. 938: 221-230. PMID 11458511 DOI: 10.1111/J.1749-6632.2001.Tb03592.X  0.375
2001 Persons DA, Allay ER, Sabatino DE, Kelly P, Bodine DM, Nienhuis AW. Functional requirements for phenotypic correction of murine beta-thalassemia: implications for human gene therapy. Blood. 97: 3275-82. PMID 11342459 DOI: 10.1182/Blood.V97.10.3275  0.42
2001 Avilés Mendoza GJ, Seidel NE, Otsu M, Anderson SM, Simon-Stoos K, Herrera A, Hoogstraten-Miller S, Malech HL, Candotti F, Puck JM, Bodine DM. Comparison of five retrovirus vectors containing the human IL-2 receptor gamma chain gene for their ability to restore T and B lymphocytes in the X-linked severe combined immunodeficiency mouse model. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 565-73. PMID 11319919 DOI: 10.1006/Mthe.2001.0292  0.43
2001 Orlic D, Kajstura J, Chimenti S, Jakoniuk I, Anderson SM, Li B, Pickel J, McKay R, Nadal-Ginard B, Bodine DM, Leri A, Anversa P. Bone marrow cells regenerate infarcted myocardium Nature. 410: 701-705. PMID 11287958 DOI: 10.1038/35070587  0.386
2000 Barrette S, Douglas JL, Seidel NE, Bodine DM. Lentivirus-based vectors transduce mouse hematopoietic stem cells with similar efficiency to moloney murine leukemia virus-based vectors. Blood. 96: 3385-91. PMID 11071632 DOI: 10.1182/Blood.V96.10.3385.H8003385_3385_3391  0.412
2000 Sabatino DE, Seidel NE, Aviles-Mendoza GJ, Cline AP, Anderson SM, Gallagher PG, Bodine DM. Long-term expression of gamma-globin mRNA in mouse erythrocytes from retrovirus vectors containing the human gamma-globin gene fused to the ankyrin-1 promoter. Proceedings of the National Academy of Sciences of the United States of America. 97: 13294-9. PMID 11069298 DOI: 10.1073/Pnas.230453097  0.484
2000 Curtis DJ, Jane SM, Hilton DJ, Dougherty L, Bodine DM, Begley CG. Adaptor protein SKAP55R is associated with myeloid differentiation and growth arrest. Experimental Hematology. 28: 1250-9. PMID 11063873 DOI: 10.1016/S0301-472X(00)00537-3  0.385
2000 Barrette S, Douglas J, Orlic D, Anderson SM, Seidel NE, Miller AD, Bodine DM. Superior transduction of mouse hematopoietic stem cells with 10A1 and VSV-G pseudotyped retrovirus vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 330-8. PMID 10933951 DOI: 10.1006/Mthe.2000.0052  0.325
2000 Otsu M, Anderson SM, Bodine DM, Puck JM, O'Shea JJ, Candotti F. Lymphoid Development and Function in X-Linked Severe Combined Immunodeficiency Mice after Stem Cell Gene Therapy Molecular Therapy. 1: 145-153. PMID 10933924 DOI: 10.1006/Mthe.1999.0020  0.479
2000 Sabatino DE, Wong C, Cline AP, Pyle L, Garrett LJ, Gallagher PG, Bodine DM. A minimal ankyrin promoter linked to a human γ-globin gene demonstrates erythroid specific copy number dependent expression with minimal position or enhancer dependence in transgenic mice Journal of Biological Chemistry. 275: 28549-28554. PMID 10878017 DOI: 10.1074/Jbc.M004043200  0.47
2000 Yang YG, Chen AM, Garrett LJ, Sergio JJ, Theodore P, Awwad M, VerHalen J, Bodine DM, Sachs DH, Sykes M. Development and analysis of transgenic mice expressing porcine hematopoietic cytokines: A model for achieving, durable porcine hematopoietic chimerism across an extensive xenogeneic barrier Xenotransplantation. 7: 58-64. PMID 10809058 DOI: 10.1034/J.1399-3089.2000.00044.X  0.351
2000 Bodine DM, Barrette S, Seidel N, Orlic D, Miller AD. Transduction of mouse hematopoietic stem cells is more efficient with 10A1 retrovirus vectors than with amphotropic vectors. Stem Cells (Dayton, Ohio). 18: 152-3. PMID 10742390 DOI: 10.1634/Stemcells.18-2-152  0.327
2000 Peters TR, Bodine DM, McDonagh KT, Lovett-Racke A, McFarland HF, McFarlin DE, Nienhuis AW, Racke MK. Retrovirus mediated gene transfer of the self antigen MBP into the bone marrow of mice alters resistance to experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 103: 51-62. PMID 10674989 DOI: 10.1016/S0165-5728(99)00181-2  0.427
2000 Orlic D, Kajstura J, Chimenti S, Li B, Anderson S, Bodine D, Pickel J, Leri A, Nadal-Ginard B, Anversa P. Exogenous Hematopoietic Stem Cells Can Regenerate Infarcted Myocardium Circulation. 102: 2672-2672. DOI: 10.1161/01.Cir.102.21.2672-G  0.367
2000 Frazar TF, Anderson SM, Cline AP, Garrett LJ, Gallagher PG, Bodine DM. The human band 3 (ae 1) promoter linked to the human ay-globin gene demonstrates erythroid specific but variegated expression in transgenic mice Blood. 96.  0.326
1999 Castilla LH, Garrett L, Adya N, Orlic D, Dutra A, Anderson S, Owens J, Eckhaus M, Bodine D, Liu PP. The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia. Nature Genetics. 23: 144-6. PMID 10508507 DOI: 10.1038/13776  0.359
1999 Horwitz ME, Malech HL, Anderson SM, Girard LJ, Bodine DM, Orlic D. Granulocyte colony-stimulating factor mobilized peripheral blood stem cells enter into G1 of the cell cycle and express higher levels of amphotropic retrovirus receptor mRNA Experimental Hematology. 27: 1160-1167. PMID 10390191 DOI: 10.1016/S0301-472X(99)00049-1  0.392
1999 Orlic D, Laprise SL, Cline AP, Anderson SM, Bodine DM. Isolation of stem cell-specific cDNAs from hematopoietic stem cell populations Annals of the New York Academy of Sciences. 872: 243-255. PMID 10372127 DOI: 10.1111/J.1749-6632.1999.Tb08469.X  0.4
1999 Orlic D, Girard LJ, Anderson SM, Barrette S, Broxmeyer HE, Bodine DM. Amphotropic retrovirus transduction of hematopoietic stem cells Annals of the New York Academy of Sciences. 872: 115-124. PMID 10372116 DOI: 10.1111/J.1749-6632.1999.Tb08458.X  0.395
1999 Orlic D, Girard LJ, Anderson SM, Bodine DM. Retrovirus receptor mRNA expression correlates with gene transfer efficiency in pluripotent hematopoietic stem cells Leukemia. 13: 52-54. PMID 10232366 DOI: 10.1038/Sj.Leu.2401287  0.394
1999 Sellers SE, Tisdale JF, Bodine DM, Williams DA, Karlsson S, Meztger M, Donahue RE, Dunbar CE. No discrepancy between in vivo gene marking efficiency assessed in peripheral blood populations compared with bone marrow progenitors or CD34+ cells Human Gene Therapy. 10: 633-640. PMID 10094206 DOI: 10.1089/10430349950018706  0.421
1999 Gallagher PG, Sabatino DE, Romana M, Cline AP, Garrett LJ, Bodine DM, Forget BG. A human β-spectrin gene promoter directs high level expression in erythroid but not muscle or neural cells Journal of Biological Chemistry. 274: 6062-6073. PMID 10037687 DOI: 10.1074/Jbc.274.10.6062  0.422
1998 Sabatino DE, Cline AP, Gallagher PG, Garrett LJ, Stamatoyannopoulos G, Forget BG, Bodine DM. Substitution of the human β-spectrin promoter for the human (A)γ- globin promoter prevents silencing of a linked human β-globin gene in transgenic mice Molecular and Cellular Biology. 18: 6634-6640. PMID 9774678 DOI: 10.1128/Mcb.18.11.6634  0.428
1998 Whitwam T, Haskins ME, Henthorn PS, Kraszewski JN, Kleiman SE, Seidel NE, Bodine DM, Puck JM. Retroviral marking of canine bone marrow: long-term, high-level expression of human interleukin-2 receptor common gamma chain in canine lymphocytes. Blood. 92: 1565-75. PMID 9716584 DOI: 10.1182/Blood.V92.5.1565.417K12_1565_1575  0.416
1998 Bodine DM, Dunbar CE, Girard LJ, Seidel NE, Cline AP, Donahue RE, Orlic D. Improved amphotropic retrovirus-mediated gene transfer into hematopoietic stem cells. Annals of the New York Academy of Sciences. 850: 139-50. PMID 9668536 DOI: 10.1111/J.1749-6632.1998.Tb10471.X  0.448
1998 Orlic D, Girard LJ, Anderson SM, Pyle LC, Yoder MC, Broxmeyer HE, Bodine DM. Identification of human and mouse hematopoietic stem cell populations expressing high levels of mRNA encoding retrovirus receptors Blood. 91: 3247-3254. PMID 9558380 DOI: 10.1182/Blood.V91.9.3247  0.416
1997 Sabatino DE, Do BQ, Pyle LC, Seidel NE, Girard LJ, Spratt SK, Orlic D, Bodine DM. Amphotropic or gibbon ape leukemia virus retrovirus binding and transduction correlates with the level of receptor mRNA in human hematopoietic cell lines. Blood Cells, Molecules & Diseases. 23: 422-33. PMID 9454686 DOI: 10.1006/Bcmd.1997.0161  0.388
1997 Dunbar CE, Tisdale J, Yu JM, Soma T, Zujewski J, Bodine D, Sellers S, Cowan K, Donahue R, Emmons R. Transduction of hematopoietic stem cells in humans and in nonhuman primates. Stem Cells (Dayton, Ohio). 135-9; discussion 13. PMID 9368333 DOI: 10.1002/Stem.5530150817  0.369
1997 Orlic D, Girard LJ, Anderson SM, Do BK, Seidel NE, Jordan CT, Bodine DM. Transduction efficiency of cell lines and hematopoietic stem cells correlates with retrovirus receptor mRNA levels. Stem Cells (Dayton, Ohio). 15: 23-8; discussion 28-. PMID 9368321 DOI: 10.1002/Stem.5530150805  0.375
1997 Yoder MC, Hiatt K, Dutt P, Mukherjee P, Bodine DM, Orlic D. Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac Immunity. 7: 335-344. PMID 9324354 DOI: 10.1016/S1074-7613(00)80355-6  0.362
1996 Dunbar CE, Seidel NE, Doren S, Sellers S, Cline AP, Metzger ME, Agricola BA, Donahue RE, Bodine DM. Improved retroviral gene transfer into murine and Rhesus peripheral blood or bone marrow repopulating cells primed in vivo with stem cell factor and granulocyte colony-stimulating factor. Proceedings of the National Academy of Sciences of the United States of America. 93: 11871-6. PMID 8876230 DOI: 10.1073/Pnas.93.21.11871  0.425
1996 Orlic D, Girard LJ, Jordan CT, Anderson SM, Cline AP, Bodine DM. The level of mRNA encoding the amphotropic retrovirus receptor in mouse and human hematopoietic stem cells is low and correlates with the efficiency of retrovirus transduction. Proceedings of the National Academy of Sciences of the United States of America. 93: 11097-102. PMID 8855315 DOI: 10.1073/Pnas.93.20.11097  0.392
1996 Bodine DM, Seidel NE, Orlic D. Bone marrow collected 14 days after in vivo administration of granulocyte colony-stimulating factor and stem cell factor to mice has 10-fold more repopulating ability than untreated bone marrow. Blood. 88: 89-97. PMID 8704206 DOI: 10.1182/Blood.V88.1.89.Bloodjournal88189  0.369
1995 Orlic D, Anderson S, Biesecker LG, Sorrentino BP, Bodine DM. Pluripotent hematopoietic stem cells contain high levels of mRNA for c- kit, GATA-2, p45 NF-E2, and c-myb and low levels or no mRNA for c-fms and the receptors for granulocyte colony-stimulating factor and interleukins 5 and 7 Proceedings of the National Academy of Sciences of the United States of America. 92: 4601-4605. PMID 7538677 DOI: 10.1073/Pnas.92.10.4601  0.345
1995 Bock TA, Orlic D, Dunbar CE, Broxmeyer HE, Bodine DM. Improved engraftment of human hematopoietic cells in severe combined immunodeficient (SCID) mice carrying human cytokine transgenes. The Journal of Experimental Medicine. 182: 2037-43. PMID 7500049 DOI: 10.1084/Jem.182.6.2037  0.395
1995 Farina SF, Girard LJ, Vanin EF, Nienhuis AW, Bodine DM. Dysregulated expression of GATA-1 following retrovirus-mediated gene transfer into murine hematopoietic stem cells increases erythropoiesis. Blood. 86: 4124-33. PMID 7492769 DOI: 10.1182/Blood.V86.11.4124.Bloodjournal86114124  0.46
1994 Cockayne DA, Bodine DM, Cline A, Nienhuis AW, Dunbar CE. Transgenic mice expressing antisense interleukin-3 RNA develop a B-cell lymphoproliferative syndrome or neurologic dysfunction. Blood. 84: 2699-710. PMID 7919383 DOI: 10.1182/Blood.V84.8.2699.2699  0.377
1994 Bodine DM, Seidel NE, Gale MS, Nienhuis AW, Orlic D. Efficient retrovirus transduction of mouse pluripotent hematopoietic stem cells mobilized into the peripheral blood by treatment with granulocyte colony-stimulating factor and stem cell factor. Blood. 84: 1482-91. PMID 7520774 DOI: 10.1182/Blood.V84.5.1482.1482  0.405
1994 Dunbar CE, Bodine DM, Sorrentino B, Donahue R, McDonagh K, Cottler-Fox M, O'Shaughnessy J, Cowan K, Carter C, Doren S, Cassell A, Nienhuis AW, Brenner MK. Gene transfer into hematopoietic cells. Implications for cancer therapy Annals of the New York Academy of Sciences. 716: 216-224. PMID 7517651 DOI: 10.1111/J.1749-6632.1994.Tb21714.X  0.349
1993 Sykes M, Sachs DH, Nienhuis AW, Pearson DA, Moulton AD, Bodine DM. Specific prolongation of skin graft survival following retroviral transduction of bone marrow with an allogeneic major histocompatibility complex gene. Transplantation. 55: 197-202. PMID 8420048 DOI: 10.1097/00007890-199301000-00037  0.369
1993 Bodine DM, Moritz T, Donahue RE, Luskey BD, Kessler SW, Martin DI, Orkin SH, Nienhuis AW, Williams DA. Long-term in vivo expression of a murine adenosine deaminase gene in rhesus monkey hematopoietic cells of multiple lineages after retroviral mediated gene transfer into CD34+ bone marrow cells. Blood. 82: 1975-80. PMID 7691243 DOI: 10.1182/Blood.V82.7.1975.Bloodjournal8271975  0.472
1993 Orlic D, Fischer R, Nishikawa S, Nienhuis AW, Bodine DM. Purification and characterization of heterogeneous pluripotent hematopoietic stem cell populations expressing high levels of c-kit receptor. Blood. 82: 762-70. PMID 7687891 DOI: 10.1182/Blood.V82.3.762.762  0.365
1993 Bodine DM, Seidel NE, Zsebo KM, Orlic D. In vivo administration of stem cell factor to mice increases the absolute number of pluripotent hematopoietic stem cells. Blood. 82: 445-55. PMID 7687160 DOI: 10.1182/Blood.V82.2.445.Bloodjournal822445  0.416
1993 Bodine D, Moritz T, Donahue R, Luskey B, Kessler S, Martin D, Orkin S, Nienhuis A, Williams D. Long-term in vivo expression of a murine adenosine deaminase gene in rhesus monkey hematopoietic cells of multiple lineages after retroviral mediated gene transfer into CD34+ bone marrow cells Blood. 82: 1975-1980. DOI: 10.1182/blood.v82.7.1975.1975  0.372
1992 Lowrey CH, Bodine DM, Nienhuis AW. Mechanism of DNase I hypersensitive site formation within the human globin locus control region Proceedings of the National Academy of Sciences of the United States of America. 89: 1143-1147. PMID 1736298 DOI: 10.1073/Pnas.89.3.1143  0.434
1992 Donahue RE, Kessler SW, Bodine D, McDonagh K, Dunbar C, Goodman S, Agricola B, Byrne E, Raffeld M, Moen R, Bacher J, Zsebo KM, Nienhuis AW. Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer Journal of Experimental Medicine. 176: 1125-1135. PMID 1383375 DOI: 10.1084/Jem.176.4.1125  0.402
1992 Bodine DM, Orlic D, Birkett NC, Seidel NE, Zsebo KM. Stem cell factor increases colony-forming unit-spleen number in vitro in synergy with interleukin-6, and in vivo in Sl/Sld mice as a single factor. Blood. 79: 913-9. PMID 1371079 DOI: 10.1182/Blood.V79.4.913.Bloodjournal794913  0.324
1992 Sorrentino BP, Brandt SJ, Bodine D, Gottesman M, Pastan I, Cline A, Nienhuis AW. Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1 Science. 257: 99-103. PMID 1352414 DOI: 10.1126/Science.1352414  0.387
1992 Bodine DM, McDonagh KT, Donahue RE, Nienhuis AW. Gene insertion into hematopoietic stem cells Experimental Hematology. 20: 125-126.  0.304
1990 Brandt SJ, Bodine DM, Dunbar CE, Nienhuis AW. Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice Journal of Clinical Investigation. 86: 592-599. PMID 2384605 DOI: 10.1172/Jci114749  0.352
1990 Bodine DM, McDonagh KT, Brandt SJ, Ney PA, Agricola B, Byrne E, Nienhuis AW. Development of a high-titer retrovirus producer cell line capable of gene transfer into thesus monkey hematopoietic stem cells Proceedings of the National Academy of Sciences of the United States of America. 87: 3738-3742. PMID 2339117 DOI: 10.1073/Pnas.87.10.3738  0.412
1990 Sorrentino B, Ney P, Bodine D, Nienhius AW. A 46 base pair enhancer sequence within the locus activating region is required for induced expression of the gamma-globin gene during erythroid differentiation. Nucleic Acids Research. 18: 2721-31. PMID 2339058 DOI: 10.1093/Nar/18.9.2721  0.453
1990 Bodine DM, McDonagh KT, Seidel NE, Nienhuis AW. Development of a high-titer retrovirus producer cell line and strategies for retrovirus-mediated gene transfer into rhesus monkey hematopoietic stem cells. Annals of the New York Academy of Sciences. 612: 415-26. PMID 2291568 DOI: 10.1111/J.1749-6632.1990.Tb24329.X  0.401
1990 Purucker M, Bodine D, Lin H, McDonagh K, Nienhuis AW. Structure and function of the enhancer 3′ to the human Aγ globin gene Nucleic Acids Research. 18: 7407-7415. PMID 2259631 DOI: 10.1093/Nar/18.24.7407  0.382
1990 Brandt SJ, Bodine DM, Dunbar CE, Nienhuis AW. Retroviral-mediated transfer of interleukin-6 into hematopoietic cells of mice results in a syndrome resembling Castgleman's disease Current Topics in Microbiology and Immunology. 166: 37-41. PMID 2073814 DOI: 10.1007/978-3-642-75889-8_5  0.35
1989 Bodine DM, Karlsson S, Nienhuis AW. Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells Proceedings of the National Academy of Sciences of the United States of America. 86: 8897-8901. PMID 2813429 DOI: 10.1073/Pnas.86.22.8897  0.392
1989 Bodine DM, Karlsson S, Papayannopoulou T, Nienhuis AW. Expression of human beta globin genes introduced into primitive murine hematopoietic progenitor cells by retrovirus mediated gene transfer Progress in Clinical and Biological Research. 316: 219-233. PMID 2694174  0.318
1989 Bodine DM, Karlsson S, Papayannopoulou T, Nienhuis AW. Introduction and expression of human beta globin genes into primitive murine hematopoietic progenitor cells by retrovirus mediated gene transfer Progress in Clinical and Biological Research. 319: 589-599; discussion . PMID 2622930  0.317
1989 Wong PMC, Chung SW, Dunbar CE, Bodine DM, Ruscetti S, Nienhuis AW. Retrovirus-mediated transfer and expression of the interleukin-3 gene in mouse hematopoietic cells result in a myeloproliferative disorder Molecular and Cellular Biology. 9: 798-808. PMID 2565534 DOI: 10.1128/Mcb.9.2.798  0.438
1989 Lin HJ, Bodine DM, Rutherford TR, Anagnou NP, McDonagh KT, Ley TJ, Nienhuis AW. Regulatory regions flanking the human fetal γ-globin genes Annals of the New York Academy of Sciences. 565: 13-22. PMID 2476058 DOI: 10.1111/J.1749-6632.1989.Tb24145.X  0.376
1988 Karlsson S, Bodine DM, Perry L, Papayannopoulou T, Nienhuis AW. Expression of the human β-globin gene folllowing retroviral-mediated transfer into multipotential hematopoietic progenitors of mice Proceedings of the National Academy of Sciences of the United States of America. 85: 6062-6066. PMID 3413076 DOI: 10.1073/Pnas.85.16.6062  0.422
1987 Bodine DM, Ley TJ. An enhancer element lies 3' to the human A gamma globin gene Embo Journal. 6: 2997-3004. PMID 3691478 DOI: 10.1002/J.1460-2075.1987.Tb02605.X  0.465
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