Ana M. Gamero - Publications

Affiliations: 
Biochemistry Temple University, Philadelphia, PA, United States 
Area:
Biochemistry, Oncology

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Canar J, Darling K, Dadey R, Gamero AM. The duality of STAT2 mediated type I interferon signaling in the tumor microenvironment and chemoresistance. Cytokine. 161: 156081. PMID 36327541 DOI: 10.1016/j.cyto.2022.156081  0.418
2021 Gallucci S, Meka S, Gamero AM. Abnormalities of the type I interferon signaling pathway in lupus autoimmunity. Cytokine. 146: 155633. PMID 34340046 DOI: 10.1016/j.cyto.2021.155633  0.352
2020 Qiu CC, Kotredes KP, Cremers T, Patel S, Afanassiev A, Slifker M, Gallucci S, Gamero AM. Targeted Stat2 deletion in conventional dendritic cells impairs CTL responses but does not affect antibody production. Oncoimmunology. 10: 1860477. PMID 33457079 DOI: 10.1080/2162402X.2020.1860477  0.432
2019 Wang P, Gamero AM, Jensen LE. IL-36 promotes anti-viral immunity by boosting sensitivity to IFN-α/β in IRF1 dependent and independent manners. Nature Communications. 10: 4700. PMID 31619669 DOI: 10.1038/S41467-019-12318-Y  0.416
2019 Wilson RP, Tursi SA, Rapsinski GJ, Medeiros NJ, Le LS, Kotredes KP, Patel S, Liverani E, Sun S, Zhu W, Kilpatrick L, Winter SE, Gamero AM, Tükel Ç. STAT2 dependent Type I Interferon response promotes dysbiosis and luminal expansion of the enteric pathogen Salmonella Typhimurium. Plos Pathogens. 15: e1007745. PMID 31009517 DOI: 10.1371/Journal.Ppat.1007745  0.432
2018 Gamero AM, Kotredes K, Abezis A, Gohimukkula SR, Afanassiev A, Cremers T, Swain JJ. Abstract 3157: p53 inactivation and STAT2 cooperate to enhance migration and metastasis of colon tumor cells Cancer Research. 78: 3157-3157. DOI: 10.1158/1538-7445.Am2018-3157  0.47
2017 Mo X, Zhang H, Preston S, Martin K, Zhou B, Vadalia N, Gamero AM, Soboloff J, Tempera I, Zaidi MR. Interferon-ᵷ2; signaling in melanocytes and melanoma cells regulates expression of CTLA-4. Cancer Research. PMID 29150430 DOI: 10.1158/0008-5472.Can-17-1615  0.405
2017 Kotredes KP, Thomas B, Gamero AM. The Protective Role of Type I Interferons in the Gastrointestinal Tract. Frontiers in Immunology. 8: 410. PMID 28428788 DOI: 10.3389/Fimmu.2017.00410  0.376
2017 Hooper KM, Yen JH, Kong W, Rahbari KM, Kuo PC, Gamero AM, Ganea D. Prostaglandin E2 Inhibition of IL-27 Production in Murine Dendritic Cells: A Novel Mechanism That Involves IRF1. Journal of Immunology (Baltimore, Md. : 1950). PMID 28062696 DOI: 10.4049/Jimmunol.1601073  0.377
2016 Steen HC, Kotredes KP, Nogusa S, Harris MY, Balachandran S, Gamero AM. Phosphorylation of STAT2 on Serine-734 negatively regulates the IFNα-induced antiviral response. Journal of Cell Science. PMID 27802159 DOI: 10.1242/Jcs.185421  0.438
2016 Raje V, Derecka M, Cantwell M, Meier J, Szczepanek K, Sisler JD, Strobl B, Gamero A, Harris TE, Larner AC. Kinase inactive Tyrosine kinase (Tyk2) Supports Differentiation of Brown fat Cells. Endocrinology. en20152048. PMID 27802075 DOI: 10.1210/En.2015-2048  0.326
2016 Xu J, Lee MH, Chakhtoura M, Green BL, Kotredes KP, Chain RW, Sriram U, Gamero AM, Gallucci S. STAT2 Is Required for TLR-Induced Murine Dendritic Cell Activation and Cross-Presentation. Journal of Immunology (Baltimore, Md. : 1950). PMID 27233962 DOI: 10.4049/Jimmunol.1500152  0.494
2015 Duerr CU, McCarthy CD, Mindt BC, Rubio M, Meli AP, Pothlichet J, Eva MM, Gauchat JF, Qureshi ST, Mazer BD, Mossman KL, Malo D, Gamero AM, Vidal SM, King IL, et al. Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells. Nature Immunology. PMID 26595887 DOI: 10.1038/Ni.3308  0.439
2015 Shao WH, Gamero AM, Zhen Y, Lobue MJ, Priest SO, Albandar HJ, Cohen PL. Stat1 Regulates Lupus-like Chronic Graft-versus-Host Disease Severity via Interactions with Stat3. Journal of Immunology (Baltimore, Md. : 1950). PMID 26392462 DOI: 10.4049/Jimmunol.1501353  0.426
2015 Yue C, Xu J, Tan Estioko MD, Kotredes KP, Lopez-Otalora Y, Hilliard BA, Baker DP, Gallucci S, Gamero AM. Host STAT2/type I interferon axis controls tumor growth. International Journal of Cancer. 136: 117-26. PMID 24895110 DOI: 10.1002/Ijc.29004  0.64
2015 Kotredes K, Gamero AM. Abstract 1201: Characterization of the effects of IDH2 mutations and (R)-2-HG in cancer progression Cancer Research. 75: 1201-1201. DOI: 10.1158/1538-7445.Am2015-1201  0.346
2015 Wilson RP, Tükel Ç, Gamero AM. ID: 224 Cytokine. 76: 106. DOI: 10.1016/J.Cyto.2015.08.228  0.392
2014 McComb S, Cessford E, Alturki NA, Joseph J, Shutinoski B, Startek JB, Gamero AM, Mossman KL, Sad S. Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages. Proceedings of the National Academy of Sciences of the United States of America. 111: E3206-13. PMID 25049377 DOI: 10.1073/Pnas.1407068111  0.46
2014 Sheikh F, Dickensheets H, Gamero AM, Vogel SN, Donnelly RP. An essential role for IFN-β in the induction of IFN-stimulated gene expression by LPS in macrophages. Journal of Leukocyte Biology. 96: 591-600. PMID 25024400 DOI: 10.1189/Jlb.2A0414-191R  0.411
2014 Xu J, Zoltick PW, Gamero AM, Gallucci S. TLR ligands up-regulate Trex1 expression in murine conventional dendritic cells through type I Interferon and NF-κB-dependent signaling pathways. Journal of Leukocyte Biology. 96: 93-103. PMID 24598055 DOI: 10.1189/Jlb.2A0713-393Rr  0.429
2014 Donnelly RP, Sheikh F, Dickensheets H, Gamero AM, Vogel SN. 38 Cytokine. 70: 37. DOI: 10.1016/J.Cyto.2014.07.045  0.424
2013 Steen HC, Gamero AM. STAT2 phosphorylation and signaling. Jak-Stat. 2: e25790. PMID 24416652 DOI: 10.4161/jkst.25790  0.309
2013 Alazawi W, Heath H, Waters JA, Woodfin A, O'Brien AJ, Scarzello AJ, Ma B, Lopez-Otalora Y, Jacobs M, Petts G, Goldin RD, Nourshargh S, Gamero AM, Foster GR. Stat2 loss leads to cytokine-independent, cell-mediated lethality in LPS-induced sepsis. Proceedings of the National Academy of Sciences of the United States of America. 110: 8656-61. PMID 23653476 DOI: 10.1073/Pnas.1221652110  0.441
2013 Kotredes KP, Gamero AM. Interferons as inducers of apoptosis in malignant cells. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 33: 162-70. PMID 23570382 DOI: 10.1089/jir.2012.0110  0.328
2013 Steen HC, Nogusa S, Thapa RJ, Basagoudanavar SH, Gill AL, Merali S, Barrero CA, Balachandran S, Gamero AM. Identification of STAT2 serine 287 as a novel regulatory phosphorylation site in type I interferon-induced cellular responses. The Journal of Biological Chemistry. 288: 747-58. PMID 23139419 DOI: 10.1074/Jbc.M112.402529  0.45
2012 Steen HC, Gamero AM. The role of signal transducer and activator of transcription-2 in the interferon response. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 32: 103-10. PMID 22280068 DOI: 10.1089/jir.2011.0099  0.335
2012 Yue C, Soboloff J, Gamero AM. Control of type I interferon-induced cell death by Orai1-mediated calcium entry in T cells. The Journal of Biological Chemistry. 287: 3207-16. PMID 22144678 DOI: 10.1074/Jbc.M111.269068  0.551
2012 Yue C, Gamero AM. Abstract 3994: Loss of STAT2 enhances the establishment of B16 melanoma tumors Cancer Research. 72: 3994-3994. DOI: 10.1158/1538-7445.Am2012-3994  0.635
2012 Yue C, Xu J, Gallucci S, Gamero A. P058 A requirement for type I interferon/Stat2 signals in restricting the establishment of melanoma Cytokine. 59: 537. DOI: 10.1016/J.Cyto.2012.06.143  0.622
2011 Zhang Q, Sturgill JL, Kmieciak M, Szczepanek K, Derecka M, Koebel C, Graham LJ, Dai Y, Chen S, Grant S, Cichy J, Shimoda K, Gamero A, Manjili M, Bear H, et al. The role of Tyk2 in regulation of breast cancer growth. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 31: 671-7. PMID 21864028 DOI: 10.1089/Jir.2011.0023  0.424
2011 Yue C, Gamero AM. PS1-099 Loss of STAT2 enhances the establishment of B16 melanoma tumors. Cytokine. 56: 42. DOI: 10.1016/J.Cyto.2011.07.131  0.558
2010 Steen HC, Gamero AM. Interferon-lambda as a potential therapeutic agent in cancer treatment. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 30: 597-602. PMID 20645876 DOI: 10.1089/jir.2010.0058  0.336
2010 Gamero AM, Young MR, Mentor-Marcel R, Bobe G, Scarzello AJ, Wise J, Colburn NH. STAT2 contributes to promotion of colorectal and skin carcinogenesis. Cancer Prevention Research (Philadelphia, Pa.). 3: 495-504. PMID 20233899 DOI: 10.1158/1940-6207.Capr-09-0105  0.461
2010 Romero-Weaver AL, Wang HW, Steen HC, Scarzello AJ, Hall VL, Sheikh F, Donnelly RP, Gamero AM. Resistance to IFN-alpha-induced apoptosis is linked to a loss of STAT2. Molecular Cancer Research : McR. 8: 80-92. PMID 20068068 DOI: 10.1158/1541-7786.Mcr-08-0344  0.442
2010 Gamero AM, Young MR, Mentor-Marcel R, Bobe G, Scarzello AJ, Wise J, Colburn NH. Abstract A27: STAT2 contributes to promotion of colorectal and skin carcinogenesis Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-A27  0.462
2010 Yue C, Soboloff J, Gamero AM. PS3-29 A defect in store-operated calcium entry sensitizes T cells to Type I interferon-induced apoptosis Cytokine. 52: 87-88. DOI: 10.1016/J.Cyto.2010.07.368  0.519
2010 Steen HC, Basagoudanavar SH, Thapa R, Balachandran S, Gamero AM. PS1-66 A phosphomimetic substitution of STAT2 serine-287 negatively regulates STAT2 function and type I interferon signaling Cytokine. 52: 31. DOI: 10.1016/J.Cyto.2010.07.138  0.397
2009 Steen HC, Gamero AM. Characterization of putative STAT2 phosphorylation sites that regulate the cellular responses to type I interferons Cytokine. 48: 128-129. DOI: 10.1016/J.Cyto.2009.07.544  0.36
2008 Maher SG, Sheikh F, Scarzello AJ, Romero-Weaver AL, Baker DP, Donnelly RP, Gamero AM. IFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity. Cancer Biology & Therapy. 7: 1109-15. PMID 18698163 DOI: 10.4161/cbt.7.7.6192  0.373
2007 Maher SG, Romero-Weaver AL, Scarzello AJ, Gamero AM. Interferon: Cellular executioner or white knight? Current Medicinal Chemistry. 14: 1279-1289. PMID 17504213 DOI: 10.2174/092986707780597907  0.37
2007 Scarzello AJ, Romero-Weaver AL, Maher SG, Veenstra TD, Zhou M, Qin A, Donnelly RP, Sheikh F, Gamero AM. A Mutation in the SH2 domain of STAT2 prolongs tyrosine phosphorylation of STAT1 and promotes type I IFN-induced apoptosis. Molecular Biology of the Cell. 18: 2455-62. PMID 17442890 DOI: 10.1091/mbc.E06-09-0843  0.37
2006 Gamero AM, Potla R, Wegrzyn J, Szelag M, Edling AE, Shimoda K, Link DC, Dulak J, Baker DP, Tanabe Y, Grayson JM, Larner AC. Activation of Tyk2 and Stat3 is required for the apoptotic actions of interferon-beta in primary pro-B cells. The Journal of Biological Chemistry. 281: 16238-44. PMID 16601124 DOI: 10.1074/Jbc.M509516200  0.359
2004 Gamero AM, Sakamoto S, Montenegro J, Larner AC. Identification of a novel conserved motif in the STAT family that is required for tyrosine phosphorylation. The Journal of Biological Chemistry. 279: 12379-85. PMID 14722125 DOI: 10.1074/Jbc.M310787200  0.316
2004 Sakamoto S, Qin J, Navarro A, Gamero A, Potla R, Yi T, Zhu W, Baker DP, Feldman G, Larner AC. Cells previously desensitized to type 1 interferons display different mechanisms of activation of stat-dependent gene expression from naïve cells. The Journal of Biological Chemistry. 279: 3245-53. PMID 14600148 DOI: 10.1074/Jbc.M309631200  0.328
2001 Gamero AM, Larner AC. Vanadate Facilitates Interferon α-mediated Apoptosis That Is Dependent on the Jak/Stat Pathway Journal of Biological Chemistry. 276: 13547-13553. PMID 11278370 DOI: 10.1074/Jbc.M007948200  0.348
1995 Djeu JY, Gamero AM, Reintgen DS, Puleo CA, Ussery D. Interleukin 15 Induction of Lymphokine-activated Killer Cell Function against Autologous Tumor Cells in Melanoma Patient Lymphocytes by a CD18-Dependent, Perforin-related Mechanism Cancer Research. 55: 4988-4994. PMID 7585540  0.308
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