| Year |
Citation |
Score |
| 2023 |
Rao D, Kwak G, Wang H, Eberhart CG, Hanes J, Suk JS. Bioreducible Gene Delivery Platform that Promotes Intracellular Payload Release and Widespread Brain Dispersion. Acs Biomaterials Science & Engineering. PMID 37523785 DOI: 10.1021/acsbiomaterials.3c00799 |
0.677 |
|
| 2023 |
Wang F, Huang Q, Su H, Sun M, Wang Z, Chen Z, Zheng M, Chakroun RW, Monroe MK, Chen D, Wang Z, Gorelick N, Serra R, Wang H, Guan Y, ... ... Hanes J, et al. Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative treatment of glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 120: e2204621120. PMID 37098055 DOI: 10.1073/pnas.2204621120 |
0.566 |
|
| 2023 |
Zierden HC, DeLong K, Zulfiqar F, Ortiz JO, Laney V, Bensouda S, Hernández N, Hoang TM, Lai SK, Hanes J, Burke AE, Ensign LM. Cervicovaginal mucus barrier properties during pregnancy are impacted by the vaginal microbiome. Frontiers in Cellular and Infection Microbiology. 13: 1015625. PMID 37065197 DOI: 10.3389/fcimb.2023.1015625 |
0.471 |
|
| 2023 |
Negron K, Kwak G, Wang H, Li H, Huang YT, Chen SW, Tyler B, Eberhart CG, Hanes J, Suk JS. A Highly Translatable Dual-arm Local Delivery Strategy To Achieve Widespread Therapeutic Coverage in Healthy and Tumor-bearing Brain Tissues. Small (Weinheim An Der Bergstrasse, Germany). e2207278. PMID 36651002 DOI: 10.1002/smll.202207278 |
0.62 |
|
| 2022 |
Andrade da Silva LH, Vieira JB, Cabral MR, Antunes MA, Lee D, Cruz FF, Hanes J, Rocco PRM, Morales MM, Suk JS. Development of nintedanib nanosuspension for inhaled treatment of experimental silicosis. Bioengineering & Translational Medicine. 8: e10401. PMID 36925690 DOI: 10.1002/btm2.10401 |
0.617 |
|
| 2021 |
Kim N, Kwak G, Rodriguez J, Livraghi-Butrico A, Zuo X, Simon V, Han E, Shenoy SK, Pandey N, Mazur M, Birket SE, Kim A, Rowe SM, Boucher R, Hanes J, et al. Inhaled gene therapy of preclinical muco-obstructive lung diseases by nanoparticles capable of breaching the airway mucus barrier. Thorax. PMID 34697091 DOI: 10.1136/thoraxjnl-2020-215185 |
0.66 |
|
| 2021 |
Kim YC, Hsueh HT, Kim N, Rodriguez J, Leo KT, Rao D, West NE, Hanes J, Suk JS. Strategy to enhance dendritic cell-mediated DNA vaccination in the lung. Advanced Therapeutics. 4. PMID 33709020 DOI: 10.1002/adtp.202000228 |
0.609 |
|
| 2021 |
Morgan LE, Jaramillo AM, Shenoy SK, Raclawska D, Emezienna NA, Richardson VL, Hara N, Harder AQ, NeeDell JC, Hennessy CE, El-Batal HM, Magin CM, Grove Villalon DE, Duncan G, Hanes JS, et al. Disulfide disruption reverses mucus dysfunction in allergic airway disease. Nature Communications. 12: 249. PMID 33431872 DOI: 10.1038/s41467-020-20499-0 |
0.57 |
|
| 2020 |
Kim YC, Shin MD, Hackett SF, Hsueh HT, Lima E Silva R, Date A, Han H, Kim BJ, Xiao A, Kim Y, Ogunnaike L, Anders NM, Hemingway A, He P, Jun AS, ... ... Hanes J, et al. Gelling hypotonic polymer solution for extended topical drug delivery to the eye. Nature Biomedical Engineering. PMID 32895514 DOI: 10.1038/S41551-020-00606-8 |
0.329 |
|
| 2020 |
Yang J, Luo L, Oh Y, Meng T, Chai G, Xia S, Emmert D, Wang B, Eberhart CG, Lee S, Stark WJ, Ensign LM, Hanes J, Xu Q. Sunitinib malate-loaded biodegradable microspheres for the prevention of corneal neovascularization in rats. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32822742 DOI: 10.1016/J.Jconrel.2020.08.019 |
0.335 |
|
| 2020 |
da Silva AL, de Oliveira GP, Kim N, Cruz FF, Kitoko JZ, Blanco NG, Martini SV, Hanes J, Rocco PRM, Suk JS, Morales MM. Nanoparticle-based thymulin gene therapy therapeutically reverses key pathology of experimental allergic asthma. Science Advances. 6: eaay7973. PMID 32577505 DOI: 10.1126/Sciadv.Aay7973 |
0.659 |
|
| 2020 |
Curley CT, Mead BP, Negron K, Kim N, Garrison WJ, Miller GW, Kingsmore KM, Thim EA, Song J, Munson JM, Klibanov AL, Suk JS, Hanes J, Price RJ. Augmentation of brain tumor interstitial flow via focused ultrasound promotes brain-penetrating nanoparticle dispersion and transfection. Science Advances. 6: eaay1344. PMID 32494662 DOI: 10.1126/Sciadv.Aay1344 |
0.653 |
|
| 2020 |
Negron K, Zhu C, Chen SW, Shahab S, Rao D, Raabe EH, Eberhart CG, Hanes J, Suk JS. Non-adhesive and highly stable biodegradable nanoparticles that provide widespread and safe transgene expression in orthotopic brain tumors. Drug Delivery and Translational Research. PMID 32323162 DOI: 10.1007/S13346-020-00759-8 |
0.678 |
|
| 2020 |
Thakur SS, Shenoy SK, Soo Suk J, Hanes JS, Rupenthal ID. Validation of hyaluronic acid-agar-based hydrogels as vitreous humor mimetics for in vitro drug and particle migration evaluations. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 31981693 DOI: 10.1016/J.Ejpb.2020.01.008 |
0.324 |
|
| 2020 |
Hoang T, Toler E, DeLong K, Mafunda NA, Bloom SM, Zierden HC, Moench TR, Coleman JS, Hanes J, Kwon DS, Lai SK, Cone RA, Ensign LM. The cervicovaginal mucus barrier to HIV-1 is diminished in bacterial vaginosis. Plos Pathogens. 16: e1008236. PMID 31971984 DOI: 10.1371/Journal.Ppat.1008236 |
0.512 |
|
| 2020 |
Kim YC, Hsueh HT, Kim N, Rodriguez J, Leo KT, Rao D, West NE, Hanes J, Suk JS. Strategy to Enhance Dendritic Cell‐Mediated DNA Vaccination in the Lung Advanced Therapeutics. 3: 2000013. DOI: 10.1002/adtp.202000013 |
0.566 |
|
| 2019 |
Mead BP, Curley CT, Kim N, Negron K, Garrison WJ, Song J, Rao D, Miller GW, Mandell JW, Purow BW, Suk JS, Hanes J, Price RJ. Focused Ultrasound Preconditioning for Augmented Nanoparticle Penetration and Efficacy in the Central Nervous System. Small (Weinheim An Der Bergstrasse, Germany). e1903460. PMID 31642183 DOI: 10.1002/Smll.201903460 |
0.696 |
|
| 2019 |
Chisholm JF, Shenoy SK, Shade JK, Kim V, Putcha N, Carson KA, Wise R, Hansel NN, Hanes JS, Suk JS, Neptune E. Nanoparticle diffusion in spontaneously expectorated sputum as a biophysical tool to probe disease severity in COPD. The European Respiratory Journal. PMID 31164433 DOI: 10.1183/13993003.00088-2019 |
0.605 |
|
| 2019 |
Fernandez-Petty CM, Hughes GW, Bowers HL, Watson JD, Rosen BH, Townsend SM, Santos C, Ridley CE, Chu KK, Li Y, Leung HM, Garcia BA, Evans TIA, Libby EF, Hathorne H, ... Hanes J, et al. A glycopolymer improves vascoelasticity and mucociliary transport of abnormal cystic fibrosis mucus. Jci Insight. 4. PMID 30996141 DOI: 10.1172/Jci.Insight.125954 |
0.329 |
|
| 2019 |
Negron K, Khalasawi N, Lu B, Ho CY, Lee J, Shenoy S, Mao HQ, Wang TH, Hanes J, Suk JS. Widespread gene transfer to malignant gliomas with In vitro-to-In vivo correlation. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30978431 DOI: 10.1016/J.Jconrel.2019.04.010 |
0.683 |
|
| 2019 |
Miller SJ, Philips T, Kim N, Dastgheyb R, Chen Z, Hsieh YC, Daigle JG, Datta M, Chew J, Vidensky S, Pham JT, Hughes EG, Robinson MB, Sattler R, Tomer R, ... ... Hanes J, et al. Molecularly defined cortical astroglia subpopulation modulates neurons via secretion of Norrin. Nature Neuroscience. PMID 30936556 DOI: 10.1038/S41593-019-0366-7 |
0.543 |
|
| 2019 |
Price RJ, Fisher DG, Suk JS, Hanes J, Ko HS, Kordower JH. Parkinson's disease gene therapy: Will focused ultrasound and nanovectors be the next frontier? Movement Disorders : Official Journal of the Movement Disorder Society. PMID 30908781 DOI: 10.1002/Mds.27675 |
0.566 |
|
| 2019 |
Wang B, Tang Y, Oh Y, Lamb NW, Xia S, Ding Z, Chen B, Suárez MJ, Meng T, Kulkarni V, Eberhart CG, Ensign LM, Stark WJ, Hanes J, Xu Q. Controlled release of dexamethasone sodium phosphate with biodegradable nanoparticles for preventing experimental corneal neovascularization. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 30677499 DOI: 10.1016/J.Nano.2019.01.001 |
0.339 |
|
| 2019 |
Luo L, Yang J, Oh Y, Hartsock MJ, Xia S, Kim YC, Ding Z, Meng T, Eberhart CG, Ensign L, Thorne JE, Stark WJ, Duh EJ, Xu Q, Hanes J. Controlled release of corticosteroid with biodegradable nanoparticles for treating experimental autoimmune uveitis. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30660629 DOI: 10.1016/J.Jconrel.2019.01.018 |
0.383 |
|
| 2019 |
Rao D, Phal A, Naga V, Negron K, Oh Y, Hanes J, Soo Suk J. EXTH-41. A NANOPARTICLE-BASED CANCER-SELECTIVE GENE TRANSFER STRATEGY FOR LOCALIZED THERAPY OF MALIGNANT HIGH GRADE GLIOMAS Neuro-Oncology. 21: vi90-vi91. DOI: 10.1093/Neuonc/Noz175.373 |
0.413 |
|
| 2018 |
Hoang T, Zierden H, Date A, Ortiz J, Gumber S, Anders N, He P, Segars J, Hanes J, Mahendroo M, Ensign LM. Development of a mucoinert progesterone nanosuspension for safer and more effective prevention of preterm birth. Journal of Controlled Release : Official Journal of the Controlled Release Society. 295: 74-86. PMID 30597245 DOI: 10.1016/J.Jconrel.2018.12.046 |
0.321 |
|
| 2018 |
Huang X, Zhuang J, Chung SW, Huang B, Halpert G, Negron K, Sun X, Yang J, Oh Y, Hwang PM, Hanes J, Suk JS. Hypoxia-Tropic Protein Nanocages for Modulation of Tumor- and Chemotherapy-Associated Hypoxia. Acs Nano. PMID 30576113 DOI: 10.1021/Acsnano.8B05399 |
0.576 |
|
| 2018 |
Date AA, Halpert G, Babu T, Ortiz J, Kanvinde P, Dimitrion P, Narayan J, Zierden H, Betageri K, Musmanno O, Wiegand H, Huang X, Gumber S, Hanes J, Ensign LM. Mucus-penetrating budesonide nanosuspension enema for local treatment of inflammatory bowel disease. Biomaterials. 185: 97-105. PMID 30236840 DOI: 10.1016/J.Biomaterials.2018.09.005 |
0.368 |
|
| 2018 |
Duncan GA, Kim N, Colon-Cortes Y, Rodriguez J, Mazur M, Birket SE, Rowe SM, West NE, Livraghi-Butrico A, Boucher RC, Hanes J, Aslanidi G, Suk JS. An Adeno-Associated Viral Vector Capable of Penetrating the Mucus Barrier to Inhaled Gene Therapy. Molecular Therapy. Methods & Clinical Development. 9: 296-304. PMID 30038933 DOI: 10.1016/J.Omtm.2018.03.006 |
0.622 |
|
| 2018 |
Osman G, Rodriguez J, Chan SY, Chisholm J, Duncan G, Kim N, Tatler AL, Shakesheff KM, Hanes J, Suk JS, Dixon JE. PEGylated enhanced cell penetrating peptide nanoparticles for lung gene therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 285: 35-45. PMID 30004000 DOI: 10.1016/J.Jconrel.2018.07.001 |
0.676 |
|
| 2018 |
Bandeira E, Oliveira H, Silva JD, Menna-Barreto RFS, Takyia CM, Suk JS, Witwer KW, Paulaitis ME, Hanes J, Rocco PRM, Morales MM. Therapeutic effects of adipose-tissue-derived mesenchymal stromal cells and their extracellular vesicles in experimental silicosis. Respiratory Research. 19: 104. PMID 29843724 DOI: 10.1186/S12931-018-0802-3 |
0.593 |
|
| 2018 |
Lu HD, Pearson E, Ristroph KD, Duncan GA, Ensign LM, Soo Suk J, Hanes J, Prud'homme RK. Pseudomonas aeruginosa Pyocyanin Production Reduced by Quorum-Sensing Inhibiting Nanocarriers. International Journal of Pharmaceutics. PMID 29608955 DOI: 10.1016/J.Ijpharm.2018.03.058 |
0.349 |
|
| 2017 |
Patil HP, Freches D, Karmani L, Duncan GA, Ucakar B, Suk JS, Hanes J, Gallez B, Vanbever R. Fate of PEGylated antibody fragments following delivery to the lungs: Influence of delivery site, PEG size and lung inflammation. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29247664 DOI: 10.1016/J.Jconrel.2017.12.009 |
0.615 |
|
| 2017 |
Kates M, Date A, Yoshida T, Afzal U, Kanvinde P, Babu T, Sopko NA, Matsui H, Hahn NM, McConkey DJ, Baras AS, Hanes J, Ensign L, Bivalacqua TJ. Preclincial Evaluation of Intravesical Cisplatin Nanoparticles for Non-Muscle-Invasive Bladder Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28808039 DOI: 10.1158/1078-0432.Ccr-17-1082 |
0.349 |
|
| 2017 |
Huang X, Chisholm J, Zhuang J, Xiao Y, Duncan G, Chen X, Suk JS, Hanes J. Protein nanocages that penetrate airway mucus and tumor tissue. Proceedings of the National Academy of Sciences of the United States of America. PMID 28739953 DOI: 10.1073/Pnas.1705407114 |
0.661 |
|
| 2017 |
Zhang C, Mastorakos P, Sobral M, Berry S, Song E, Nance E, Eberhart CG, Hanes J, Suk JS. Strategies to enhance the distribution of nanotherapeutics in the brain. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28739449 DOI: 10.1016/J.Jconrel.2017.07.028 |
0.745 |
|
| 2017 |
Mastorakos P, Zhang C, Song E, Kim YE, Park HW, Berry S, Choi WK, Hanes J, Suk JS. Biodegradable brain-penetrating DNA nanocomplexes and their use to treat malignant brain tumors. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28694032 DOI: 10.1016/J.Jconrel.2017.07.009 |
0.621 |
|
| 2017 |
Schuster BS, Allan DB, Kays JC, Hanes J, Leheny RL. Photoactivatable fluorescent probes reveal heterogeneous nanoparticle permeation through biological gels at multiple scales. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28578189 DOI: 10.1016/J.Jconrel.2017.05.035 |
0.333 |
|
| 2017 |
Mead BP, Kim N, Miller GW, Hodges D, Mastorakos P, Klibanov AL, Mandell JW, Hirsh J, Suk JS, Hanes J, Price RJ. Novel focused ultrasound gene therapy approach non-invasively restores dopaminergic neuron function in a rat Parkinson's disease model. Nano Letters. PMID 28511006 DOI: 10.1021/Acs.Nanolett.7B00616 |
0.607 |
|
| 2017 |
Schneider CS, Xu Q, Boylan NJ, Chisholm J, Tang BC, Schuster BS, Henning A, Ensign LM, Lee E, Adstamongkonkul P, Simons BW, Wang SS, Gong X, Yu T, Boyle MP, ... ... Hanes J, et al. Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation. Science Advances. 3: e1601556. PMID 28435870 DOI: 10.1126/Sciadv.1601556 |
0.797 |
|
| 2017 |
Timbie KF, Afzal U, Date A, Zhang C, Song J, Wilson Miller G, Suk JS, Hanes J, Price RJ. MR image-guided delivery of cisplatin-loaded brain-penetrating nanoparticles to invasive glioma with focused ultrasound. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28288892 DOI: 10.1016/J.Jconrel.2017.03.017 |
0.633 |
|
| 2017 |
Zhang C, Nance EA, Mastorakos P, Chisholm J, Berry S, Eberhart C, Tyler B, Brem H, Suk JS, Hanes J. Convection enhanced delivery of cisplatin-loaded brain penetrating nanoparticles cures malignant glioma in rats. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28279797 DOI: 10.1016/J.Jconrel.2017.03.007 |
0.766 |
|
| 2017 |
Mitragotri S, Lammers T, Bae YH, Schwendeman S, De Smedt S, Leroux JC, Peer D, Kwon IC, Harashima H, Kikuchi A, Oh YK, Torchilin V, Hennink W, Hanes J, Park K. Drug Delivery Research for the Future: Expanding the Nano Horizons and Beyond. Journal of Controlled Release : Official Journal of the Controlled Release Society. 246: 183-184. PMID 28110715 DOI: 10.1016/J.Jconrel.2017.01.011 |
0.324 |
|
| 2017 |
Mead B, Kim N, Negron K, Miller W, Mastorakos P, Suk JS, Kilbanov A, Hanes J, Price RJ. Intersections of neuromodulation, focused ultrasound, and gene delivery with brain-penetrating nanoparticles The Journal of the Acoustical Society of America. 142: 2669-2669. DOI: 10.1121/1.5014725 |
0.675 |
|
| 2016 |
Leite Nascimento T, Hillaireau H, Vergnaud J, Rivano M, Deloménie C, Courilleau D, Arpicco S, Suk JS, Hanes J, Fattal E. Hyaluronic acid-conjugated lipoplexes for targeted delivery of siRNA in a murine metastatic lung cancer model. International Journal of Pharmaceutics. 514: 103-111. PMID 27863652 DOI: 10.1016/J.Ijpharm.2016.06.125 |
0.6 |
|
| 2016 |
Duncan GA, Jung J, Joseph A, Thaxton AL, West NE, Boyle MP, Hanes J, Suk JS. Microstructural alterations of sputum in cystic fibrosis lung disease. Jci Insight. 1: e88198. PMID 27812540 DOI: 10.1172/Jci.Insight.88198 |
0.598 |
|
| 2016 |
Hanes J, Ensign LM, Kannan R, Suk JS. North America special issue Part II. Journal of Controlled Release : Official Journal of the Controlled Release Society. 240: 1. PMID 27725132 DOI: 10.1016/J.Jconrel.2016.09.027 |
0.551 |
|
| 2016 |
Yu T, Chisholm J, Choi WJ, Anonuevo A, Pulicare S, Zhong W, Chen M, Fridley C, Lai SK, Ensign LM, Suk JS, Hanes J. Mucus-Penetrating Nanosuspensions for Enhanced Delivery of Poorly Soluble Drugs to Mucosal Surfaces. Advanced Healthcare Materials. PMID 27717163 DOI: 10.1002/Adhm.201600599 |
0.74 |
|
| 2016 |
Berry S, Mastorakos P, Zhang C, Song E, Patel H, Suk JS, Hanes J. Enhancing Intracranial Delivery of Clinically Relevant Non-viral Gene Vectors. Rsc Advances. 48: 41665-41674. PMID 27642512 DOI: 10.1039/C6Ra01546H |
0.688 |
|
| 2016 |
Chu KK, Mojahed D, Fernandez CM, Li Y, Liu L, Wilsterman EJ, Diephuis B, Birket SE, Bowers H, Martin Solomon G, Schuster BS, Hanes J, Rowe SM, Tearney GJ. Particle-Tracking Microrheology Using Micro-Optical Coherence Tomography. Biophysical Journal. 111: 1053-1063. PMID 27602733 DOI: 10.1016/J.Bpj.2016.07.020 |
0.344 |
|
| 2016 |
Elgogary A, Xu Q, Poore B, Alt J, Zimmermann SC, Zhao L, Fu J, Chen B, Xia S, Liu Y, Neisser M, Nguyen C, Lee R, Park JK, Reyes J, ... ... Hanes J, et al. Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 27559084 DOI: 10.1073/Pnas.1611406113 |
0.413 |
|
| 2016 |
Fu J, Sun F, Liu W, Liu Y, Gedam M, Hu Q, Fridley C, Quigley HA, Hanes J, Pitha IF. Subconjunctival delivery of dorzolamide-loaded poly(ether-anhydride) microparticles produces sustained lowering of intraocular pressure in rabbits. Molecular Pharmaceutics. PMID 27336794 DOI: 10.1021/Acs.Molpharmaceut.6B00343 |
0.343 |
|
| 2016 |
Date AA, Hanes J, Ensign LM. Nanoparticles for oral delivery: Design, evaluation and state-of-the-art. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27292178 DOI: 10.1016/J.Jconrel.2016.06.016 |
0.444 |
|
| 2016 |
Kim N, Duncan GA, Hanes J, Suk JS. Barriers to inhaled gene therapy of obstructive lung diseases: A review. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27196742 DOI: 10.1016/J.Jconrel.2016.05.031 |
0.616 |
|
| 2016 |
Maisel K, Reddy M, Xu Q, Chattopadhyay S, Cone R, Ensign LM, Hanes J. Nanoparticles coated with high molecular weight PEG penetrate mucus and provide uniform vaginal and colorectal distribution in vivo. Nanomedicine (London, England). PMID 27171816 DOI: 10.2217/Nnm-2016-0047 |
0.386 |
|
| 2016 |
Zaaroor M, Sinai A, Goldsher D, Eran A, Nassar M, Schlesinger I, Parker J, Ravikumar V, Ghanouni P, Stein S, Halpern C, Krishna V, Hargrove A, Agrawal P, Changizi B, ... ... Hanes J, ... ... Hanes J, et al. 5th International Symposium on Focused Ultrasound Journal of Therapeutic Ultrasound. 4. DOI: 10.1186/S40349-016-0076-5 |
0.562 |
|
| 2016 |
Gong X, Xu Q, Song X, Yu T, Schuster B, Yang J, Lamb NW, Chang J, Hanes J. Magnetic mucus-penetrating nanoparticles for drug delivery through human cervicovaginal mucus Nanomedicine: Nanotechnology, Biology and Medicine. 12: 521. DOI: 10.1016/J.Nano.2015.12.210 |
0.422 |
|
| 2016 |
Yu T, Chisholm J, Choi WJ, Anonuevo A, Pulicare S, Zhong W, Chen M, Fridley C, Lai SK, Ensign LM, Suk JS, Hanes J. Mucus-Penetrating Nanosuspensions for Enhanced Delivery of Poorly Soluble Drugs to Mucosal Surfaces Advanced Healthcare Materials. DOI: 10.1002/adhm.201600599 |
0.704 |
|
| 2015 |
Mead BP, Mastorakos P, Suk JS, Klibanov AL, Hanes J, Price RJ. Targeted gene transfer to the brain via the delivery of brain-penetrating DNA nanoparticles with focused ultrasound. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26732553 DOI: 10.1016/J.Jconrel.2015.12.034 |
0.65 |
|
| 2015 |
Mastorakos P, Song E, Zhang C, Berry S, Park HW, Kim YE, Park JS, Lee S, Suk JS, Hanes J. Biodegradable DNA Nanoparticles that Provide Widespread Gene Delivery in the Brain. Small (Weinheim An Der Bergstrasse, Germany). PMID 26680637 DOI: 10.1002/Smll.201502554 |
0.723 |
|
| 2015 |
Suk JS, Xu Q, Kim N, Hanes J, Ensign LM. PEGylation as a strategy for improving nanoparticle-based drug and gene delivery. Advanced Drug Delivery Reviews. PMID 26456916 DOI: 10.1016/J.Addr.2015.09.012 |
0.72 |
|
| 2015 |
Xu Q, Ensign LM, Boylan NJ, Schön A, Gong X, Yang JC, Lamb NW, Cai S, Yu T, Freire E, Hanes J. Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo. Acs Nano. 9: 9217-27. PMID 26301576 DOI: 10.1021/Acsnano.5B03876 |
0.767 |
|
| 2015 |
Mastorakos P, da Silva AL, Chisholm J, Song E, Choi WK, Boyle MP, Morales MM, Hanes J, Suk JS. Highly compacted biodegradable DNA nanoparticles capable of overcoming the mucus barrier for inhaled lung gene therapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 26124127 DOI: 10.1073/Pnas.1502281112 |
0.733 |
|
| 2015 |
Maisel K, Chattopadhyay S, Moench T, Hendrix C, Cone R, Ensign LM, Hanes J. Enema ion compositions for enhancing colorectal drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 209: 280-7. PMID 25937321 DOI: 10.1016/J.Jconrel.2015.04.040 |
0.378 |
|
| 2015 |
Schuster BS, Ensign LM, Allan DB, Suk JS, Hanes J. Particle tracking in drug and gene delivery research: State-of-the-art applications and methods. Advanced Drug Delivery Reviews. PMID 25858664 DOI: 10.1016/J.Addr.2015.03.017 |
0.678 |
|
| 2015 |
Zhang F, Mastorakos P, Mishra MK, Mangraviti A, Hwang L, Zhou J, Hanes J, Brem H, Olivi A, Tyler B, Kannan RM. Uniform brain tumor distribution and tumor associated macrophage targeting of systemically administered dendrimers. Biomaterials. 52: 507-16. PMID 25818456 DOI: 10.1016/J.Biomaterials.2015.02.053 |
0.327 |
|
| 2015 |
Mastorakos P, Zhang C, Berry S, Oh Y, Lee S, Eberhart CG, Woodworth GF, Suk JS, Hanes J. Highly PEGylated DNA Nanoparticles Provide Uniform and Widespread Gene Transfer in the Brain. Advanced Healthcare Materials. 4: 1023-33. PMID 25761435 DOI: 10.1002/Adhm.201400800 |
0.704 |
|
| 2015 |
Lu HD, Spiegel AC, Hurley A, Perez LJ, Maisel K, Ensign LM, Hanes J, Bassler BL, Semmelhack MF, Prud'homme RK. Modulating Vibrio cholerae quorum-sensing-controlled communication using autoinducer-loaded nanoparticles. Nano Letters. 15: 2235-41. PMID 25651002 DOI: 10.1021/Acs.Nanolett.5B00151 |
0.405 |
|
| 2015 |
Pan Q, Xu Q, Boylan NJ, Lamb NW, Emmert DG, Yang JC, Tang L, Heflin T, Alwadani S, Eberhart CG, Stark WJ, Hanes J. Corticosteroid-loaded biodegradable nanoparticles for prevention of corneal allograft rejection in rats. Journal of Controlled Release : Official Journal of the Controlled Release Society. 201: 32-40. PMID 25576786 DOI: 10.1016/J.Jconrel.2015.01.009 |
0.703 |
|
| 2015 |
Schneider CS, Perez JG, Cheng E, Zhang C, Mastorakos P, Hanes J, Winkles JA, Woodworth GF, Kim AJ. Minimizing the non-specific binding of nanoparticles to the brain enables active targeting of Fn14-positive glioblastoma cells. Biomaterials. 42: 42-51. PMID 25542792 DOI: 10.1016/J.Biomaterials.2014.11.054 |
0.437 |
|
| 2015 |
Yu T, Chan KW, Anonuevo A, Song X, Schuster BS, Chattopadhyay S, Xu Q, Oskolkov N, Patel H, Ensign LM, van Zjil PC, McMahon MT, Hanes J. Liposome-based mucus-penetrating particles (MPP) for mucosal theranostics: demonstration of diamagnetic chemical exchange saturation transfer (diaCEST) magnetic resonance imaging (MRI). Nanomedicine : Nanotechnology, Biology, and Medicine. 11: 401-5. PMID 25461289 DOI: 10.1016/J.Nano.2014.09.019 |
0.373 |
|
| 2015 |
Maisel K, Ensign L, Reddy M, Cone R, Hanes J. Effect of surface chemistry on nanoparticle interaction with gastrointestinal mucus and distribution in the gastrointestinal tract following oral and rectal administration in the mouse. Journal of Controlled Release : Official Journal of the Controlled Release Society. 197: 48-57. PMID 25449804 DOI: 10.1016/J.Jconrel.2014.10.026 |
0.44 |
|
| 2015 |
Mastorakos P, Kambhampati SP, Mishra MK, Wu T, Song E, Hanes J, Kannan RM. Hydroxyl PAMAM dendrimer-based gene vectors for transgene delivery to human retinal pigment epithelial cells. Nanoscale. 7: 3845-56. PMID 25213606 DOI: 10.1039/C4Nr04284K |
0.395 |
|
| 2015 |
Timbie K, Zhang C, Nance E, Song J, Miller W, Hanes J, Price R. Ultrasound-mediated delivery of brain-penetrating nanoparticles across the blood-tumor barrier Journal of Therapeutic Ultrasound. 3. DOI: 10.1186/2050-5736-3-S1-P34 |
0.688 |
|
| 2015 |
Mead B, Mastorakos P, Suk JS, Song J, Hanes J, Price R. Localized delivery of non-viral gene-bearing nanoparticles into the rat brain following focused ultrasound-mediated BBB opening Journal of Therapeutic Ultrasound. 3. DOI: 10.1186/2050-5736-3-S1-P29 |
0.692 |
|
| 2015 |
Kays JC, Schuster BS, Allan DB, Hanes J, Leheny RL. Multiscale Diffusion Measurements in Biological Gels Using Photoactivatable Fluorescent Nanoparticles Biophysical Journal. 108: 173a. DOI: 10.1016/J.Bpj.2014.11.954 |
0.429 |
|
| 2015 |
Mastorakos P, Zhang C, Berry S, Oh Y, Lee S, Eberhart CG, Woodworth GF, Suk JS, Hanes J. DNA Nanoparticles: Highly PEGylated DNA Nanoparticles Provide Uniform and Widespread Gene Transfer in the Brain (Adv. Healthcare Mater. 7/2015) Advanced Healthcare Materials. 4: 942-942. DOI: 10.1002/Adhm.201570040 |
0.691 |
|
| 2014 |
Kim AJ, Woodworth GF, Boylan NJ, Suk JS, Hanes J. Highly compacted pH-responsive DNA nanoparticles mediate transgene silencing in experimental glioma. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 2: 8165-8173. PMID 25485114 DOI: 10.1039/C4Tb00559G |
0.803 |
|
| 2014 |
Birjiniuk A, Billings N, Nance E, Hanes J, Ribbeck K, Doyle PS. Single particle tracking reveals spatial and dynamic organization of the E. coli biofilm matrix. New Journal of Physics. 16: 085014. PMID 25414591 DOI: 10.1088/1367-2630/16/8/085014 |
0.565 |
|
| 2014 |
Ensign LM, Lai SK, Wang YY, Yang M, Mert O, Hanes J, Cone R. Pretreatment of human cervicovaginal mucus with pluronic F127 enhances nanoparticle penetration without compromising mucus barrier properties to herpes simplex virus. Biomacromolecules. 15: 4403-9. PMID 25347518 DOI: 10.1021/Bm501419Z |
0.679 |
|
| 2014 |
Nance E, Zhang C, Shih TY, Xu Q, Schuster BS, Hanes J. Brain-penetrating nanoparticles improve paclitaxel efficacy in malignant glioma following local administration. Acs Nano. 8: 10655-64. PMID 25259648 DOI: 10.1021/Nn504210G |
0.708 |
|
| 2014 |
Pan-In P, Wanichwecharungruang S, Hanes J, Kim AJ. Cellular trafficking and anticancer activity of Garcinia mangostana extract-encapsulated polymeric nanoparticles. International Journal of Nanomedicine. 9: 3677-86. PMID 25125977 DOI: 10.2147/Ijn.S66511 |
0.36 |
|
| 2014 |
Woodworth GF, Dunn GP, Nance EA, Hanes J, Brem H. Emerging insights into barriers to effective brain tumor therapeutics. Frontiers in Oncology. 4: 126. PMID 25101239 DOI: 10.3389/Fonc.2014.00126 |
0.629 |
|
| 2014 |
Yang M, Lai SK, Yu T, Wang YY, Happe C, Zhong W, Zhang M, Anonuevo A, Fridley C, Hung A, Fu J, Hanes J. Nanoparticle penetration of human cervicovaginal mucus: the effect of polyvinyl alcohol. Journal of Controlled Release : Official Journal of the Controlled Release Society. 192: 202-8. PMID 25090196 DOI: 10.1016/J.Jconrel.2014.07.045 |
0.691 |
|
| 2014 |
Nance E, Timbie K, Miller GW, Song J, Louttit C, Klibanov AL, Shih TY, Swaminathan G, Tamargo RJ, Woodworth GF, Hanes J, Price RJ. Non-invasive delivery of stealth, brain-penetrating nanoparticles across the blood-brain barrier using MRI-guided focused ultrasound. Journal of Controlled Release : Official Journal of the Controlled Release Society. 189: 123-32. PMID 24979210 DOI: 10.1016/J.Jconrel.2014.06.031 |
0.632 |
|
| 2014 |
Schuster BS, Kim AJ, Kays JC, Kanzawa MM, Guggino WB, Boyle MP, Rowe SM, Muzyczka N, Suk JS, Hanes J. Overcoming the cystic fibrosis sputum barrier to leading adeno-associated virus gene therapy vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1484-93. PMID 24869933 DOI: 10.1038/Mt.2014.89 |
0.668 |
|
| 2014 |
Ensign LM, Cone R, Hanes J. Nanoparticle-based drug delivery to the vagina: a review. Journal of Controlled Release : Official Journal of the Controlled Release Society. 190: 500-14. PMID 24830303 DOI: 10.1016/J.Jconrel.2014.04.033 |
0.439 |
|
| 2014 |
Yang M, Yu T, Wood J, Wang YY, Tang BC, Zeng Q, Simons BW, Fu J, Chuang CM, Lai SK, Wu TC, Hung CF, Hanes J. Intraperitoneal delivery of paclitaxel by poly(ether-anhydride) microspheres effectively suppresses tumor growth in a murine metastatic ovarian cancer model. Drug Delivery and Translational Research. 4: 203-9. PMID 24816829 DOI: 10.1007/S13346-013-0190-7 |
0.741 |
|
| 2014 |
da Silva AL, Martini SV, Abreu SC, Samary Cdos S, Diaz BL, Fernezlian S, de Sá VK, Capelozzi VL, Boylan NJ, Goya RG, Suk JS, Rocco PR, Hanes J, Morales MM. DNA nanoparticle-mediated thymulin gene therapy prevents airway remodeling in experimental allergic asthma. Journal of Controlled Release : Official Journal of the Controlled Release Society. 180: 125-33. PMID 24556417 DOI: 10.1016/J.Jconrel.2014.02.010 |
0.802 |
|
| 2014 |
Chan KW, Yu T, Qiao Y, Liu Q, Yang M, Patel H, Liu G, Kinzler KW, Vogelstein B, Bulte JW, van Zijl PC, Hanes J, Zhou S, McMahon MT. A diaCEST MRI approach for monitoring liposomal accumulation in tumors. Journal of Controlled Release : Official Journal of the Controlled Release Society. 180: 51-9. PMID 24548481 DOI: 10.1016/J.Jconrel.2014.02.005 |
0.314 |
|
| 2014 |
Suk JS, Kim AJ, Trehan K, Schneider CS, Cebotaru L, Woodward OM, Boylan NJ, Boyle MP, Lai SK, Guggino WB, Hanes J. Lung gene therapy with highly compacted DNA nanoparticles that overcome the mucus barrier. Journal of Controlled Release : Official Journal of the Controlled Release Society. 178: 8-17. PMID 24440664 DOI: 10.1016/J.Jconrel.2014.01.007 |
0.84 |
|
| 2014 |
Yang M, Yu T, Wang YY, Lai SK, Zeng Q, Miao B, Tang BC, Simons BW, Ensign LM, Liu G, Chan KW, Juang CY, Mert O, Wood J, Fu J, ... ... Hanes J, et al. Vaginal delivery of paclitaxel via nanoparticles with non-mucoadhesive surfaces suppresses cervical tumor growth. Advanced Healthcare Materials. 3: 1044-52. PMID 24339398 DOI: 10.1002/Adhm.201300519 |
0.803 |
|
| 2014 |
Mastorakos P, Zhang C, Berry S, Kim A, Woodworth G, Suk JS, Hanes J. ET-38 * BRAIN PENETRATING NON-VIRAL GENE VECTORS FOR EFFICIENT GENE TRANSFER TO BRAIN TUMORS Neuro-Oncology. 16: v87-v88. DOI: 10.1093/Neuonc/Nou255.38 |
0.674 |
|
| 2014 |
Yang M, Yu T, Wang Y, Lai SK, Zeng Q, Miao B, Tang BC, Simons BW, Ensign LM, Liu G, Chan KW, Juang C, Mert O, Wood J, Fu J, ... ... Hanes J, et al. Cancer Therapy: Vaginal Delivery of Paclitaxel via Nanoparticles with Non-Mucoadhesive Surfaces Suppresses Cervical Tumor Growth (Adv. Healthcare Mater. 7/2014) Advanced Healthcare Materials. 3: 1120-1120. DOI: 10.1002/Adhm.201470037 |
0.767 |
|
| 2013 |
Wang YY, Lai SK, Ensign LM, Zhong W, Cone R, Hanes J. The microstructure and bulk rheology of human cervicovaginal mucus are remarkably resistant to changes in pH. Biomacromolecules. 14: 4429-35. PMID 24266646 DOI: 10.1021/Bm401356Q |
0.622 |
|
| 2013 |
Iwase T, Fu J, Yoshida T, Muramatsu D, Miki A, Hashida N, Lu L, Oveson B, Lima e Silva R, Seidel C, Yang M, Connelly S, Shen J, Han B, Wu M, ... ... Hanes J, et al. Sustained delivery of a HIF-1 antagonist for ocular neovascularization. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 625-33. PMID 24126220 DOI: 10.1016/J.Jconrel.2013.10.008 |
0.421 |
|
| 2013 |
Ensign LM, Hoen TE, Maisel K, Cone RA, Hanes JS. Enhanced vaginal drug delivery through the use of hypotonic formulations that induce fluid uptake. Biomaterials. 34: 6922-9. PMID 23769419 DOI: 10.1016/j.biomaterials.2013.05.039 |
0.311 |
|
| 2013 |
Xu Q, Boylan NJ, Cai S, Miao B, Patel H, Hanes J. Scalable method to produce biodegradable nanoparticles that rapidly penetrate human mucus. Journal of Controlled Release : Official Journal of the Controlled Release Society. 170: 279-86. PMID 23751567 DOI: 10.1016/J.Jconrel.2013.05.035 |
0.769 |
|
| 2013 |
Ensign LM, Henning A, Schneider CS, Maisel K, Wang YY, Porosoff MD, Cone R, Hanes J. Ex vivo characterization of particle transport in mucus secretions coating freshly excised mucosal tissues. Molecular Pharmaceutics. 10: 2176-82. PMID 23617606 DOI: 10.1021/Mp400087Y |
0.612 |
|
| 2013 |
Kim AJ, Boylan NJ, Suk JS, Hwangbo M, Yu T, Schuster BS, Cebotaru L, Lesniak WG, Oh JS, Adstamongkonkul P, Choi AY, Kannan RM, Hanes J. Use of single-site-functionalized PEG dendrons to prepare gene vectors that penetrate human mucus barriers. Angewandte Chemie (International Ed. in English). 52: 3985-8. PMID 23460577 DOI: 10.1002/Anie.201208556 |
0.815 |
|
| 2013 |
Schuster BS, Suk JS, Woodworth GF, Hanes J. Nanoparticle diffusion in respiratory mucus from humans without lung disease. Biomaterials. 34: 3439-46. PMID 23384790 DOI: 10.1016/J.Biomaterials.2013.01.064 |
0.711 |
|
| 2013 |
Xu Q, Boylan NJ, Suk JS, Wang YY, Nance EA, Yang JC, McDonnell PJ, Cone RA, Duh EJ, Hanes J. Nanoparticle diffusion in, and microrheology of, the bovine vitreous ex vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. 167: 76-84. PMID 23369761 DOI: 10.1016/J.Jconrel.2013.01.018 |
0.819 |
|
| 2013 |
Timbie K, Burke C, Nance E, Woodworth G, Miller GW, Hanes J, Price RJ. Ultrasound-targeted delivery of systemically administered therapeutic nanoparticles The Journal of the Acoustical Society of America. 134: 4047-4047. DOI: 10.1121/1.4830769 |
0.719 |
|
| 2012 |
Kim AJ, Hanes J. The emergence of multiple particle tracking in intracellular trafficking of nanomedicines. Biophysical Reviews. 4: 83-92. PMID 28510091 DOI: 10.1007/S12551-012-0066-Y |
0.332 |
|
| 2012 |
Yu T, Wang YY, Yang M, Schneider C, Zhong W, Pulicare S, Choi WJ, Mert O, Fu J, Lai SK, Hanes J. Biodegradable mucus-penetrating nanoparticles composed of diblock copolymers of polyethylene glycol and poly(lactic-co-glycolic acid). Drug Delivery and Translational Research. 2. PMID 24205449 DOI: 10.1007/S13346-011-0048-9 |
0.712 |
|
| 2012 |
Ensign LM, Schneider C, Suk JS, Cone R, Hanes J. Mucus penetrating nanoparticles: biophysical tool and method of drug and gene delivery. Advanced Materials (Deerfield Beach, Fla.). 24: 3887-94. PMID 22988559 DOI: 10.1002/Adma.201201800 |
0.704 |
|
| 2012 |
Nance EA, Woodworth GF, Sailor KA, Shih TY, Xu Q, Swaminathan G, Xiang D, Eberhart C, Hanes J. A dense poly(ethylene glycol) coating improves penetration of large polymeric nanoparticles within brain tissue. Science Translational Medicine. 4: 149ra119. PMID 22932224 DOI: 10.1126/Scitranslmed.3003594 |
0.697 |
|
| 2012 |
Burke CW, Suk JS, Kim AJ, Hsiang YH, Klibanov AL, Hanes J, Price RJ. Markedly enhanced skeletal muscle transfection achieved by the ultrasound-targeted delivery of non-viral gene nanocarriers with microbubbles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 162: 414-21. PMID 22800583 DOI: 10.1016/J.Jconrel.2012.07.005 |
0.638 |
|
| 2012 |
Ensign LM, Tang BC, Wang YY, Tse TA, Hoen T, Cone R, Hanes J. Mucus-penetrating nanoparticles for vaginal drug delivery protect against herpes simplex virus. Science Translational Medicine. 4: 138ra79. PMID 22700955 DOI: 10.1126/Scitranslmed.3003453 |
0.743 |
|
| 2012 |
Navarrette CR, Sisson JH, Nance E, Allen-Gipson D, Hanes J, Wyatt TA. Particulate matter in cigarette smoke increases ciliary axoneme beating through mechanical stimulation. Journal of Aerosol Medicine and Pulmonary Drug Delivery. 25: 159-68. PMID 22280523 DOI: 10.1089/Jamp.2011.0890 |
0.632 |
|
| 2012 |
Ensign LM, Cone R, Hanes J. Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers. Advanced Drug Delivery Reviews. 64: 557-70. PMID 22212900 DOI: 10.1016/J.Addr.2011.12.009 |
0.455 |
|
| 2012 |
Boylan NJ, Kim AJ, Suk JS, Adstamongkonkul P, Simons BW, Lai SK, Cooper MJ, Hanes J. Enhancement of airway gene transfer by DNA nanoparticles using a pH-responsive block copolymer of polyethylene glycol and poly-L-lysine. Biomaterials. 33: 2361-71. PMID 22182747 DOI: 10.1016/J.Biomaterials.2011.11.080 |
0.821 |
|
| 2012 |
Suh J, An Y, Tang BC, Dempsey C, Huang F, Hanes J. Real-time gene delivery vector tracking in the endo-lysosomal pathway of live cells. Microscopy Research and Technique. 75: 691-7. PMID 22095650 DOI: 10.1002/Jemt.21113 |
0.668 |
|
| 2012 |
Kim AJ, Boylan NJ, Suk JS, Lai SK, Hanes J. Non-degradative intracellular trafficking of highly compacted polymeric DNA nanoparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 158: 102-7. PMID 22079809 DOI: 10.1016/J.Jconrel.2011.10.031 |
0.809 |
|
| 2012 |
Mert O, Lai SK, Ensign L, Yang M, Wang YY, Wood J, Hanes J. A poly(ethylene glycol)-based surfactant for formulation of drug-loaded mucus penetrating particles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 157: 455-60. PMID 21911015 DOI: 10.1016/J.Jconrel.2011.08.032 |
0.712 |
|
| 2012 |
Boylan NJ, Suk JS, Lai SK, Jelinek R, Boyle MP, Cooper MJ, Hanes J. Highly compacted DNA nanoparticles with low MW PEG coatings: in vitro, ex vivo and in vivo evaluation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 157: 72-9. PMID 21903145 DOI: 10.1016/J.Jconrel.2011.08.031 |
0.832 |
|
| 2012 |
Jachak A, Lai SK, Hida K, Suk JS, Markovic N, Biswal S, Breysse PN, Hanes J. Transport of metal oxide nanoparticles and single-walled carbon nanotubes in human mucus. Nanotoxicology. 6: 614-22. PMID 21800953 DOI: 10.3109/17435390.2011.598244 |
0.796 |
|
| 2011 |
Suk JS, Boylan NJ, Trehan K, Tang BC, Schneider CS, Lin JG, Boyle MP, Zeitlin PL, Lai SK, Cooper MJ, Hanes J. N-acetylcysteine Enhances Cystic Fibrosis Sputum Penetration and Airway Gene Transfer by Highly Compacted DNA Nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1981-1989. PMID 28160651 DOI: 10.1038/mt.2011.160 |
0.823 |
|
| 2011 |
Suk JS, Boylan NJ, Trehan K, Tang BC, Schneider CS, Lin JM, Boyle MP, Zeitlin PL, Lai SK, Cooper MJ, Hanes J. N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1981-9. PMID 21829177 DOI: 10.1038/Mt.2011.160 |
0.818 |
|
| 2011 |
Wang YY, Lai SK, So C, Schneider C, Cone R, Hanes J. Mucoadhesive nanoparticles may disrupt the protective human mucus barrier by altering its microstructure. Plos One. 6: e21547. PMID 21738703 DOI: 10.1371/Journal.Pone.0021547 |
0.683 |
|
| 2011 |
Lai SK, Suk JS, Pace A, Wang YY, Yang M, Mert O, Chen J, Kim J, Hanes J. Drug carrier nanoparticles that penetrate human chronic rhinosinusitis mucus. Biomaterials. 32: 6285-90. PMID 21665271 DOI: 10.1016/J.Biomaterials.2011.05.008 |
0.797 |
|
| 2011 |
Hida K, Lai SK, Suk JS, Won SY, Boyle MP, Hanes J. Common gene therapy viral vectors do not efficiently penetrate sputum from cystic fibrosis patients. Plos One. 6: e19919. PMID 21637751 DOI: 10.1371/Journal.Pone.0019919 |
0.789 |
|
| 2011 |
Suk JS, Lai SK, Boylan NJ, Dawson MR, Boyle MP, Hanes J. Rapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated with N-acetyl cysteine. Nanomedicine (London, England). 6: 365-75. PMID 21385138 DOI: 10.2217/Nnm.10.123 |
0.82 |
|
| 2011 |
Yang M, Lai SK, Wang YY, Zhong W, Happe C, Zhang M, Fu J, Hanes J. Biodegradable nanoparticles composed entirely of safe materials that rapidly penetrate human mucus. Angewandte Chemie (International Ed. in English). 50: 2597-600. PMID 21370345 DOI: 10.1002/Anie.201006849 |
0.723 |
|
| 2011 |
Lai SK, Wang YY, Hida K, Cone R, Hanes J. Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses (Journal of Biological Chemistry (2010) 107, 2 (598-603) DOI: 10.1073/pnas.0911748107) Proceedings of the National Academy of Sciences of the United States of America. 108: 14371. DOI: 10.1073/Pnas.1111693108 |
0.689 |
|
| 2010 |
Whaley KJ, Hanes J, Shattock R, Cone RA, Friend DR. Novel approaches to vaginal delivery and safety of microbicides: biopharmaceuticals, nanoparticles, and vaccines. Antiviral Research. 88: S55-66. PMID 21109069 DOI: 10.1016/J.Antiviral.2010.09.006 |
0.354 |
|
| 2010 |
Aich U, Meledeo MA, Sampathkumar SG, Fu J, Jones MB, Weier CA, Chung SY, Tang BC, Yang M, Hanes J, Yarema KJ. Development of delivery methods for carbohydrate-based drugs: controlled release of biologically-active short chain fatty acid-hexosamine analogs. Glycoconjugate Journal. 27: 445-59. PMID 20458533 DOI: 10.1007/S10719-010-9292-3 |
0.658 |
|
| 2010 |
Hida K, Won SY, Di Pasquale G, Hanes J, Chiorini JA, Ostermeier M. Sites in the AAV5 capsid tolerant to deletions and tandem duplications. Archives of Biochemistry and Biophysics. 496: 1-8. PMID 20102698 DOI: 10.1016/J.Abb.2010.01.009 |
0.718 |
|
| 2010 |
Lai SK, Wang YY, Hida K, Cone R, Hanes J. Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses. Proceedings of the National Academy of Sciences of the United States of America. 107: 598-603. PMID 20018745 DOI: 10.1073/Pnas.0911748107 |
0.73 |
|
| 2010 |
Tang BC, Fu J, Watkins DN, Hanes J. Enhanced efficacy of local etoposide delivery by poly(ether-anhydride) particles against small cell lung cancer in vivo. Biomaterials. 31: 339-44. PMID 19796810 DOI: 10.1016/J.Biomaterials.2009.09.033 |
0.682 |
|
| 2009 |
Tang BC, Dawson M, Lai SK, Wang YY, Suk JS, Yang M, Zeitlin P, Boyle MP, Fu J, Hanes J. Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier. Proceedings of the National Academy of Sciences of the United States of America. 106: 19268-73. PMID 19901335 DOI: 10.1073/Pnas.0905998106 |
0.84 |
|
| 2009 |
Lai SK, Hida K, Shukair S, Wang YY, Figueiredo A, Cone R, Hope TJ, Hanes J. Human immunodeficiency virus type 1 is trapped by acidic but not by neutralized human cervicovaginal mucus. Journal of Virology. 83: 11196-200. PMID 19692470 DOI: 10.1128/Jvi.01899-08 |
0.691 |
|
| 2009 |
Hanes J, Demeester J. Drug and gene delivery to mucosal tissues: the mucus barrier. Preface. Advanced Drug Delivery Reviews. 61: 73-4. PMID 19244608 DOI: 10.1016/J.Addr.2009.01.002 |
0.382 |
|
| 2009 |
Suk JS, Lai SK, Wang YY, Ensign LM, Zeitlin PL, Boyle MP, Hanes J. The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles. Biomaterials. 30: 2591-7. PMID 19176245 DOI: 10.1016/J.Biomaterials.2008.12.076 |
0.808 |
|
| 2009 |
Lai SK, Wang YY, Cone R, Wirtz D, Hanes J. Altering mucus rheology to "solidify" human mucus at the nanoscale. Plos One. 4: e4294. PMID 19173002 DOI: 10.1371/Journal.Pone.0004294 |
0.655 |
|
| 2009 |
Lai SK, Wang YY, Wirtz D, Hanes J. Micro- and macrorheology of mucus. Advanced Drug Delivery Reviews. 61: 86-100. PMID 19166889 DOI: 10.1016/J.Addr.2008.09.012 |
0.676 |
|
| 2009 |
Lai SK, Wang YY, Hanes J. Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues. Advanced Drug Delivery Reviews. 61: 158-71. PMID 19133304 DOI: 10.1016/J.Addr.2008.11.002 |
0.717 |
|
| 2008 |
Wang YY, Lai SK, Suk JS, Pace A, Cone R, Hanes J. Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that "slip" through the human mucus barrier. Angewandte Chemie (International Ed. in English). 47: 9726-9. PMID 18979480 DOI: 10.1002/Anie.200803526 |
0.81 |
|
| 2008 |
Lai SK, Hanes J. Real-time multiple particle tracking of gene nanocarriers in complex biological environments. Methods in Molecular Biology (Clifton, N.J.). 434: 81-97. PMID 18470640 DOI: 10.1007/978-1-60327-248-3_6 |
0.592 |
|
| 2008 |
Deosarkar SP, Malgor R, Fu J, Kohn LD, Hanes J, Goetz DJ. Polymeric particles conjugated with a ligand to VCAM-1 exhibit selective, avid, and focal adhesion to sites of atherosclerosis. Biotechnology and Bioengineering. 101: 400-7. PMID 18428114 DOI: 10.1002/Bit.21885 |
0.328 |
|
| 2008 |
Lai SK, Hida K, Chen C, Hanes J. Characterization of the intracellular dynamics of a non-degradative pathway accessed by polymer nanoparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 125: 107-11. PMID 18053606 DOI: 10.1016/J.Jconrel.2007.10.015 |
0.683 |
|
| 2007 |
Suh J, Choy KL, Lai SK, Suk JS, Tang BC, Prabhu S, Hanes J. PEGylation of nanoparticles improves their cytoplasmic transport. International Journal of Nanomedicine. 2: 735-41. PMID 18203439 |
0.819 |
|
| 2007 |
Hida K, Hanes J, Ostermeier M. Directed evolution for drug and nucleic acid delivery. Advanced Drug Delivery Reviews. 59: 1562-78. PMID 17933418 DOI: 10.1016/J.Addr.2007.08.022 |
0.712 |
|
| 2007 |
Lai SK, Hida K, Man ST, Chen C, Machamer C, Schroer TA, Hanes J. Privileged delivery of polymer nanoparticles to the perinuclear region of live cells via a non-clathrin, non-degradative pathway. Biomaterials. 28: 2876-84. PMID 17363053 DOI: 10.1016/J.Biomaterials.2007.02.021 |
0.734 |
|
| 2007 |
Suk JS, Suh J, Lai SK, Hanes J. Quantifying the intracellular transport of viral and nonviral gene vectors in primary neurons. Experimental Biology and Medicine (Maywood, N.J.). 232: 461-9. PMID 17327481 DOI: 10.3181/00379727-232-2320461 |
0.728 |
|
| 2007 |
Lai SK, O'Hanlon DE, Harrold S, Man ST, Wang YY, Cone R, Hanes J. Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus. Proceedings of the National Academy of Sciences of the United States of America. 104: 1482-7. PMID 17244708 DOI: 10.1073/Pnas.0608611104 |
0.694 |
|
| 2006 |
Suk JS, Suh J, Choy K, Lai SK, Fu J, Hanes J. Gene delivery to differentiated neurotypic cells with RGD and HIV Tat peptide functionalized polymeric nanoparticles. Biomaterials. 27: 5143-50. PMID 16769110 DOI: 10.1016/J.Biomaterials.2006.05.013 |
0.739 |
|
| 2006 |
Hanes J. New polymeric nanomedicines for targeted and controlled drug delivery Nanomedicine: Nanotechnology, Biology and Medicine. 2: 273. DOI: 10.1016/J.Nano.2006.10.018 |
0.336 |
|
| 2005 |
Fiegel J, Jin F, Hanes J, Stebe K. Wetting of a particle in a thin film. Journal of Colloid and Interface Science. 291: 507-14. PMID 15946673 DOI: 10.1016/J.Jcis.2005.05.014 |
0.661 |
|
| 2005 |
Sakhalkar HS, Hanes J, Fu J, Benavides U, Malgor R, Borruso CL, Kohn LD, Kurjiaka DT, Goetz DJ. Enhanced adhesion of ligand-conjugated biodegradable particles to colitic venules. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 792-4. PMID 15764649 DOI: 10.1096/Fj.04-2668Fje |
0.35 |
|
| 2005 |
Suh J, Dawson M, Hanes J. Real-time multiple-particle tracking: applications to drug and gene delivery. Advanced Drug Delivery Reviews. 57: 63-78. PMID 15518921 DOI: 10.1016/J.Addr.2004.06.001 |
0.643 |
|
| 2005 |
Suh J, Dawson M, Hanes J. Corrigendum to “Real-time multiple-particle tracking: Applications to drug and gene delivery” [Advanced Drug Delivery Reviews 57(2005)63–78] Advanced Drug Delivery Reviews. 57: 1551. DOI: 10.1016/J.Addr.2005.05.003 |
0.605 |
|
| 2005 |
Har-El YE, Van Zanten JH, Hanes J. Stability of high density Pei/Vegf DNA nanocomplexes in physiological fluids Aiche Annual Meeting, Conference Proceedings. 14304. |
0.72 |
|
| 2004 |
Dawson M, Krauland E, Wirtz D, Hanes J. Transport of polymeric nanoparticle gene carriers in gastric mucus. Biotechnology Progress. 20: 851-7. PMID 15176891 DOI: 10.1021/Bp0342553 |
0.671 |
|
| 2004 |
Fiegel J, Fu J, Hanes J. Poly(ether-anhydride) dry powder aerosols for sustained drug delivery in the lungs. Journal of Controlled Release : Official Journal of the Controlled Release Society. 96: 411-23. PMID 15120898 DOI: 10.1016/J.Jconrel.2004.02.018 |
0.708 |
|
| 2004 |
Suh J, Wirtz D, Hanes J. Real-time intracellular transport of gene nanocarriers studied by multiple particle tracking. Biotechnology Progress. 20: 598-602. PMID 15059007 DOI: 10.1021/Bp034251Y |
0.373 |
|
| 2004 |
Fu J, Fiegel J, Hanes J. Synthesis and characterization of PEG-based ether-anhydride terpolymers: Novel polymers for controlled drug delivery Macromolecules. 37: 7174-7180. DOI: 10.1021/Ma049853S |
0.692 |
|
| 2004 |
Suk JS, Suh J, Hanes J. Cellular uptake and intracellular transport of viral and non-viral gene vectors in differentiated neurons affected in Parkinson's Disease Aiche Annual Meeting, Conference Proceedings. 1085-1086. |
0.575 |
|
| 2004 |
Dawson M, Wirtz D, Hanes J. Gene carriers modified with PEG demonstrate increased transport and stability in mucus as explored with high-resolution nanoparticle tracking Aiche Annual Meeting, Conference Proceedings. 6345. |
0.334 |
|
| 2004 |
Suh J, An Y, Tang B, Suk JS, Hanes J. Real-time correlation of intracellular gene vector transport rates with biological location in live mesenchymal stem cells Aiche Annual Meeting, Conference Proceedings. 2187-2188. |
0.572 |
|
| 2003 |
Sakhalkar HS, Dalal MK, Salem AK, Ansari R, Fu J, Kiani MF, Kurjiaka DT, Hanes J, Shakesheff KM, Goetz DJ. Leukocyte-inspired biodegradable particles that selectively and avidly adhere to inflamed endothelium in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 100: 15895-900. PMID 14668435 DOI: 10.1073/Pnas.2631433100 |
0.326 |
|
| 2003 |
Dawson M, Wirtz D, Hanes J. Enhanced viscoelasticity of human cystic fibrotic sputum correlates with increasing microheterogeneity in particle transport. The Journal of Biological Chemistry. 278: 50393-401. PMID 13679362 DOI: 10.1074/Jbc.M309026200 |
0.611 |
|
| 2003 |
Fiegel J, Ehrhardt C, Schaefer UF, Lehr CM, Hanes J. Large porous particle impingement on lung epithelial cell monolayers--toward improved particle characterization in the lung. Pharmaceutical Research. 20: 788-96. PMID 12751635 DOI: 10.1023/A:1023441804464 |
0.695 |
|
| 2003 |
Suh J, Wirtz D, Hanes J. Efficient active transport of gene nanocarriers to the cell nucleus. Proceedings of the National Academy of Sciences of the United States of America. 100: 3878-82. PMID 12644705 DOI: 10.1073/Pnas.0636277100 |
0.363 |
|
| 2002 |
Fu J, Fiegel J, Krauland E, Hanes J. New polymeric carriers for controlled drug delivery following inhalation or injection. Biomaterials. 23: 4425-33. PMID 12219833 DOI: 10.1016/S0142-9612(02)00182-5 |
0.722 |
|
| 2002 |
Ehrhardt C, Fiegel J, Fuchs S, Abu-Dahab R, Schaefer UF, Hanes J, Lehr CM. Drug absorption by the respiratory mucosa: cell culture models and particulate drug carriers. Journal of Aerosol Medicine : the Official Journal of the International Society For Aerosols in Medicine. 15: 131-9. PMID 12184863 DOI: 10.1089/089426802320282257 |
0.706 |
|
| 2002 |
Ehrhardt C, Kneuer C, Fiegel J, Hanes J, Schaefer UF, Kim KJ, Lehr CM. Influence of apical fluid volume on the development of functional intercellular junctions in the human epithelial cell line 16HBE14o-: implications for the use of this cell line as an in vitro model for bronchial drug absorption studies. Cell and Tissue Research. 308: 391-400. PMID 12107432 DOI: 10.1007/S00441-002-0548-5 |
0.651 |
|
| 2002 |
Van Zanten JH, Har-El Y, Hanes J. Optimization of PEI/VEGF DNA polyplexes for potenital delivery from tissue engineering scaffolds Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 563-564. |
0.76 |
|
| 2002 |
Fu J, Krauland E, Har-el YE, Hanes J. New degradable cationic polyesters for nonviral gene delivery Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 551-552. |
0.754 |
|
| 2001 |
Hanes J, Sills A, Zhao Z, Suh KW, Tyler B, DiMeco F, Brat DJ, Choti MA, Leong KW, Pardoll DM, Brem H. Controlled local delivery of interleukin-2 by biodegradable polymers protects animals from experimental brain tumors and liver tumors. Pharmaceutical Research. 18: 899-906. PMID 11496947 DOI: 10.1023/A:1010963307097 |
0.323 |
|
| 1998 |
Evora C, Soriano I, Rogers RA, Shakesheff KM, Hanes J, Langer R. Relating the phagocytosis of microparticles by alveolar macrophages to surface chemistry: The effect of 1,2-dipalmitoylphosphatidylcholine Journal of Controlled Release. 51: 143-152. PMID 9685911 DOI: 10.1016/S0168-3659(97)00149-1 |
0.383 |
|
| 1997 |
Batycky RP, Hanes J, Langer R, Edwards DA. A theoretical model of erosion and macromolecular drug release from biodegrading microspheres. Journal of Pharmaceutical Sciences. 86: 1464-77. PMID 9423163 DOI: 10.1021/Js9604117 |
0.315 |
|
| 1997 |
Edwards DA, Hanes J, Caponetti G, Hrkach J, Ben-Jebria A, Eskew ML, Mintzes J, Deaver D, Lotan N, Langer R. Large porous particles for pulmonary drug delivery. Science (New York, N.Y.). 276: 1868-71. PMID 9188534 DOI: 10.1126/Science.276.5320.1868 |
0.367 |
|
| 1996 |
Hanes J, Chiba M, Langer R. Synthesis and Characterization of Degradable Anhydride-co-imide Terpolymers Containing Trimellitylimido-l-tyrosine: Novel Polymers for Drug Delivery Macromolecules. 29: 5279-5287. DOI: 10.1021/Ma960393F |
0.306 |
|
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