Deneys R. van der Westhuyzen - Publications

Affiliations: 
Molecular and Cellular Biochemistry University of Kentucky, Lexington, KY 
Area:
Biochemistry

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Li J, Pijut SS, Wang Y, Ji A, Kaur R, Temel RE, van der Westhuyzen DR, Graf GA. Simultaneous Determination of Biliary and Intestinal Cholesterol Secretion Reveals That CETP (Cholesteryl Ester Transfer Protein) Alters Elimination Route in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119312952. PMID 31462090 DOI: 10.1161/Atvbaha.119.312952  0.443
2016 Kim MH, De Beer MC, Wroblewski JM, Charnigo RJ, Ji A, Webb NR, De Beer FC, Van der Westhuyzen DR. Impact of individual acute phase serum amyloid A (SAA) isoforms on HDL metabolism in mice. Journal of Lipid Research. PMID 27018443 DOI: 10.1194/jlr.M062174  0.358
2014 Ji A, Wroblewski JM, Webb NR, van der Westhuyzen DR. Impact of phospholipid transfer protein on nascent high-density lipoprotein formation and remodeling. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1910-6. PMID 25060793 DOI: 10.1161/ATVBAHA.114.303533  0.366
2014 Meyer JM, Ji A, Cai L, van der Westhuyzen DR. Minimally oxidized LDL inhibits macrophage selective cholesteryl ester uptake and native LDL-induced foam cell formation. Journal of Lipid Research. 55: 1648-1656. PMID 24891335 DOI: 10.1194/jlr.M044644  0.399
2013 Meyer JM, Graf GA, van der Westhuyzen DR. New developments in selective cholesteryl ester uptake. Current Opinion in Lipidology. 24: 386-92. PMID 23842142 DOI: 10.1097/Mol.0B013E3283638042  0.475
2012 Meyer JM, Ji A, Cai L, van der Westhuyzen DR. High-capacity selective uptake of cholesteryl ester from native LDL during macrophage foam cell formation. Journal of Lipid Research. 53: 2081-91. PMID 22833685 DOI: 10.1194/jlr.M026534  0.473
2012 Ji A, Wroblewski JM, Cai L, de Beer MC, Webb NR, van der Westhuyzen DR. Nascent HDL formation in hepatocytes and role of ABCA1, ABCG1, and SR-BI. Journal of Lipid Research. 53: 446-55. PMID 22190590 DOI: 10.1194/jlr.M017079  0.382
2011 Wroblewski JM, Jahangiri A, Ji A, De Beer FC, Van Der Westhuyzen DR, Webb NR. Nascent HDL formation by hepatocytes is reduced by the concerted action of serum amyloid A and endothelial lipase Journal of Lipid Research. 52: 2255-2261. PMID 21957202 DOI: 10.1194/jlr.M017681  0.388
2011 Ji A, Meyer JM, Cai L, Akinmusire A, de Beer MC, Webb NR, van der Westhuyzen DR. Scavenger receptor SR-BI in macrophage lipid metabolism. Atherosclerosis. 217: 106-12. PMID 21481393 DOI: 10.1016/j.atherosclerosis.2011.03.017  0.427
2011 De Beer MC, Ji A, Jahangiri A, Vaughan AM, De Beer FC, Van Der Westhuyzen DR, Webb NR. ATP binding cassette G1-dependent cholesterol efflux during inflammation Journal of Lipid Research. 52: 345-353. PMID 21138980 DOI: 10.1194/jlr.M012328  0.4
2009 Neyen C, Plüddemann A, Roversi P, Thomas B, Cai L, van der Westhuyzen DR, Sim RB, Gordon S. Macrophage scavenger receptor A mediates adhesion to apolipoproteins A-I and E. Biochemistry. 48: 11858-71. PMID 19911804 DOI: 10.1021/Bi9013769  0.359
2009 de Beer MC, Webb NR, Whitaker NL, Wroblewski JM, Jahangiri A, van der Westhuyzen DR, de Beer FC. SR-BI selective lipid uptake: subsequent metabolism of acute phase HDL. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1298-303. PMID 19304574 DOI: 10.1161/ATVBAHA.109.186502  0.321
2009 Neumann S, Coudreuse DY, van der Westhuyzen DR, Eckhardt ER, Korswagen HC, Schmitz G, Sprong H. Mammalian Wnt3a is released on lipoprotein particles. Traffic (Copenhagen, Denmark). 10: 334-43. PMID 19207483 DOI: 10.1111/j.1600-0854.2008.00872.x  0.403
2009 Boyanovsky BB, Shridas P, Simons M, van der Westhuyzen DR, Webb NR. Syndecan-4 mediates macrophage uptake of group V secretory phospholipase A2-modified LDL. Journal of Lipid Research. 50: 641-50. PMID 19056705 DOI: 10.1194/jlr.M800450-JLR200  0.475
2007 Sun B, Boyanovsky BB, Connelly MA, Shridas P, Van Der Westhuyzen DR, Webb NR. Distinct mechanisms for OxLDL uptake and cellular trafficking by class B scavenger receptors CD36 and SR-BI Journal of Lipid Research. 48: 2560-2570. PMID 17876058 DOI: 10.1194/jlr.M700163-JLR200  0.34
2006 Shetty S, Eckhardt ER, Post SR, van der Westhuyzen DR. Phosphatidylinositol-3-kinase regulates scavenger receptor class B type I subcellular localization and selective lipid uptake in hepatocytes. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 2125-31. PMID 16794223 DOI: 10.1161/01.Atv.0000233335.26362.37  0.654
2006 Sun B, Eckhardt ER, Shetty S, van der Westhuyzen DR, Webb NR. Quantitative analysis of SR-BI-dependent HDL retroendocytosis in hepatocytes and fibroblasts. Journal of Lipid Research. 47: 1700-13. PMID 16705213 DOI: 10.1194/jlr.M500450-JLR200  0.638
2006 Pagler TA, Rhode S, Neuhofer A, Laggner H, Strobl W, Hinterndorfer C, Volf I, Pavelka M, Eckhardt ER, van der Westhuyzen DR, Schütz GJ, Stangl H. SR-BI-mediated high density lipoprotein (HDL) endocytosis leads to HDL resecretion facilitating cholesterol efflux. The Journal of Biological Chemistry. 281: 11193-204. PMID 16488891 DOI: 10.1074/jbc.M510261200  0.467
2006 Eckhardt ER, Cai L, Shetty S, Zhao Z, Szanto A, Webb NR, Van der Westhuyzen DR. High density lipoprotein endocytosis by scavenger receptor SR-BII is clathrin-dependent and requires a carboxyl-terminal dileucine motif. The Journal of Biological Chemistry. 281: 4348-53. PMID 16368683 DOI: 10.1074/jbc.M513154200  0.644
2005 van der Westhuyzen DR, Cai L, de Beer MC, de Beer FC. Serum amyloid A promotes cholesterol efflux mediated by scavenger receptor B-I. The Journal of Biological Chemistry. 280: 35890-5. PMID 16120612 DOI: 10.1074/jbc.M505685200  0.535
2005 de Beer MC, van der Westhuyzen DR, Whitaker NL, Webb NR, de Beer FC. SR-BI-mediated selective lipid uptake segregates apoA-I and apoA-II catabolism. Journal of Lipid Research. 46: 2143-50. PMID 16061955 DOI: 10.1194/jlr.M500068-JLR200  0.337
2005 Boyanovsky BB, van der Westhuyzen DR, Webb NR. Group V secretory phospholipase A2-modified low density lipoprotein promotes foam cell formation by a SR-A- and CD36-independent process that involves cellular proteoglycans. The Journal of Biological Chemistry. 280: 32746-52. PMID 16040605 DOI: 10.1074/jbc.M502067200  0.506
2005 Out R, Hoekstra M, de Jager SC, de Vos P, van der Westhuyzen DR, Webb NR, Van Eck M, Biessen EA, Van Berkel TJ. Adenovirus-mediated hepatic overexpression of scavenger receptor class B type I accelerates chylomicron metabolism in C57BL/6J mice. Journal of Lipid Research. 46: 1172-81. PMID 15772431 DOI: 10.1194/jlr.M400361-JLR200  0.387
2005 Cai L, de Beer MC, de Beer FC, van der Westhuyzen DR. Serum amyloid A is a ligand for scavenger receptor class B type I and inhibits high density lipoprotein binding and selective lipid uptake. The Journal of Biological Chemistry. 280: 2954-61. PMID 15561721 DOI: 10.1074/jbc.M411555200  0.566
2005 Zhao Z, de Beer MC, Cai L, Asmis R, de Beer FC, de Villiers WJ, van der Westhuyzen DR. Low-density lipoprotein from apolipoprotein E-deficient mice induces macrophage lipid accumulation in a CD36 and scavenger receptor class A-dependent manner. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 168-73. PMID 15514202 DOI: 10.1161/01.Atv.0000149145.00865.D9  0.386
2004 Webb NR, de Beer MC, Asztalos BF, Whitaker N, van der Westhuyzen DR, de Beer FC. Remodeling of HDL remnants generated by scavenger receptor class B type I. Journal of Lipid Research. 45: 1666-73. PMID 15210842 DOI: 10.1194/jlr.M400026-JLR200  0.375
2004 de Beer MC, Castellani LW, Cai L, Stromberg AJ, de Beer FC, van der Westhuyzen DR. ApoA-II modulates the association of HDL with class B scavenger receptors SR-BI and CD36. Journal of Lipid Research. 45: 706-15. PMID 14729860 DOI: 10.1194/jlr.M300417-JLR200  0.368
2004 Begg MJ, Sturrock ED, Van Der Westhuyzen DR. Soluble LDL-R are formed by cell surface cleavage in response to phorbol esters European Journal of Biochemistry. 271: 524-533. PMID 14728679 DOI: 10.1046/j.1432-1033.2003.03953.x  0.497
2004 Eckhardt ER, Cai L, Sun B, Webb NR, van der Westhuyzen DR. High density lipoprotein uptake by scavenger receptor SR-BII. The Journal of Biological Chemistry. 279: 14372-81. PMID 14726519 DOI: 10.1074/jbc.M313793200  0.603
2004 Cai L, Eckhardt ER, Shi W, Zhao Z, Nasser M, de Villiers WJ, van der Westhuyzen DR. Scavenger receptor class B type I reduces cholesterol absorption in cultured enterocyte CaCo-2 cells. Journal of Lipid Research. 45: 253-62. PMID 14617739 DOI: 10.1194/jlr.M300303-JLR200  0.558
2004 Webb NR, de Beer MC, de Beer FC, van der Westhuyzen DR. ApoB-containing lipoproteins in apoE-deficient mice are not metabolized by the class B scavenger receptor BI. Journal of Lipid Research. 45: 272-80. PMID 14563829 DOI: 10.1194/jlr.M300319-JLR200  0.498
2002 Webb NR, Cai L, Ziemba KS, Yu J, Kindy MS, van der Westhuyzen DR, de Beer FC. The fate of HDL particles in vivo after SR-BI-mediated selective lipid uptake. Journal of Lipid Research. 43: 1890-8. PMID 12401888 DOI: 10.1194/Jlr.M200173-Jlr200  0.469
2002 Webb NR, de Beer MC, Yu J, Kindy MS, Daugherty A, van der Westhuyzen DR, de Beer FC. Overexpression of SR-BI by adenoviral vector promotes clearance of apoA-I, but not apoB, in human apoB transgenic mice. Journal of Lipid Research. 43: 1421-8. PMID 12235173 DOI: 10.1194/Jlr.M200026-Jlr200  0.512
2002 Goti D, Hrzenjak A, Levak-Frank S, Frank S, van der Westhuyzen DR, Malle E, Sattler W. Scavenger receptor class B, type I is expressed in porcine brain capillary endothelial cells and contributes to selective uptake of HDL-associated vitamin E. Journal of Neurochemistry. 76: 498-508. PMID 11208913 DOI: 10.1046/j.1471-4159.2001.00100.x  0.514
2001 Matveev S, Uittenbogaard A, Van Der Westhuyzen D, Smart EJ. Caveolin-1 negatively regulates SR-BI mediated selective uptake of high-density lipoprotein-derived cholesteryl ester European Journal of Biochemistry. 268: 5609-5616. PMID 11683884 DOI: 10.1046/J.1432-1033.2001.02496.X  0.56
2001 de Beer MC, Durbin DM, Cai L, Mirocha N, Jonas A, Webb NR, de Beer FC, van Der Westhuyzen DR. Apolipoprotein A-II modulates the binding and selective lipid uptake of reconstituted high density lipoprotein by scavenger receptor BI. The Journal of Biological Chemistry. 276: 15832-9. PMID 11279034 DOI: 10.1074/Jbc.M100228200  0.514
1999 Graf GA, Connell PM, van der Westhuyzen DR, Smart EJ. The class B, type I scavenger receptor promotes the selective uptake of high density lipoprotein cholesterol ethers into caveolae. The Journal of Biological Chemistry. 274: 12043-8. PMID 10207027 DOI: 10.1074/Jbc.274.17.12043  0.513
1999 Fluiter K, Sattler W, De Beer MC, Connell PM, Van Der Westhuyzen DR, Van Berkel TJC. Scavenger receptor BI mediates the selective uptake of oxidized cholesterol esters by rat liver Journal of Biological Chemistry. 274: 8893-8899. PMID 10085133 DOI: 10.1074/jbc.274.13.8893  0.47
1999 Reaven E, Lua Y, Nomoto A, Temel R, Williams DL, Van Der Westhuyzen DR, Azhar S. The selective pathway and a high-density lipoprotein receptor (SR-BI) in ovarian granulosa cells of the mouse Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1436: 565-576. PMID 9989286 DOI: 10.1016/S0005-2760(98)00169-6  0.515
1998 Webb NR, Connell PM, Graf GA, Smart EJ, de Villiers WJ, de Beer FC, van der Westhuyzen DR. SR-BII, an isoform of the scavenger receptor BI containing an alternate cytoplasmic tail, mediates lipid transfer between high density lipoprotein and cells. The Journal of Biological Chemistry. 273: 15241-8. PMID 9614139 DOI: 10.1074/jbc.273.24.15241  0.596
1997 Langenhoven E, Warnich L, Thiart R, Rubinsztein DC, van der Westhuyzen DR, Marais AD, Kotze MJ. Two novel point mutations causing receptor-negative familial hypercholesterolemia in a South African Indian homozygote. Atherosclerosis. 125: 111-9. PMID 8831933 DOI: 10.1016/0021-9150(96)05871-6  0.481
1996 Steyn K, Goldberg YP, Kotze MJ, Steyn M, Swanepoel AS, Fourie JM, Coetzee GA, Van der Westhuyzen DR. Estimation of the prevalence of familial hypercholesterolaemia in a rural Afrikaner community by direct screening for three Afrikaner founder low density lipoprotein receptor gene mutations. Human Genetics. 98: 479-84. PMID 8792826 DOI: 10.1007/s004390050243  0.389
1995 Van Roggen JFG, Van der Westhuyzen DR, Coetzee GA, Marais AD, Steyn K, Langenhoven E, Kotze MJ. FH Afrikaner-3 LDL receptor mutation results in defective LDL receptors and causes a mild form of familial hypercholesterolemia Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 765-772. PMID 7773731  0.42
1993 Kotze MJ, De Villiers WJS, Steyn K, Kriek JA, Marais AD, Langenhoven E, Herbert JS, Graadt Van Roggen JF, Van Der Westhuyzen DR, Coetzee GA. Phenotypic variation among familial hypercholesterolemics heterozygous for either one of two afrikaner founder LDL receptor mutations Arteriosclerosis, Thrombosis, and Vascular Biology. 13: 1460-1468. PMID 8399083  0.323
1993 Rubinsztein DC, Jialal I, Leitersdorf E, Coetzee GA, van der Westhuyzen DR. Identification of two new LDL-receptor mutations causing homozygous familial hypercholesterolemia in a South African of Indian origin Bba - Molecular Basis of Disease. 1182: 75-82. PMID 8347689 DOI: 10.1016/0925-4439(93)90156-U  0.519
1993 Rubinsztein DC, Raal FJ, Seftel HC, Pilcher G, Coetzee GA, Van der Westhuyzen DR. Characterization of six patients who are double heterozygotes for familial hypercholesterolemia and familial defective apo B-100 Arteriosclerosis and Thrombosis. 13: 1076-1081. PMID 8318509  0.482
1992 Fourie AM, Coetzee GA, Gevers W, Van Der Westhuyzen DR. Low-density lipoprotein receptor point mutation results in expression of both active and inactive surface forms of the same mutant receptor Biochemistry®. 31: 12754-12759. PMID 1463746 DOI: 10.1021/Bi00166A007  0.461
1991 van der Westhuyzen DR, Stein ML, Henderson HE, Marais AD, Fourie AM, Coetzee GA. Deletion of two growth-factor repeats from the low-density-lipoprotein receptor accelerates its degradation Biochemical Journal. 277: 677-682. PMID 1872803  0.435
1990 Rubinsztein DC, Cohen JC, Berger GM, Van Der Westhuyzen DR, Coetzee GA, Gevers W. Chylomicron remnant clearance from the plasma is normal in familial hypercholesterolemic homozygotes with defined receptor defects Journal of Clinical Investigation. 86: 1306-1312. PMID 2212015  0.528
1990 Grant KI, Casciola LA, Coetzee GA, Sanan DA, Gevers W, van der Westhuyzen DR. Ammonium chloride causes reversible inhibition of low density lipoprotein receptor recycling and accelerates receptor degradation. Journal of Biological Chemistry. 265: 4041-4047. DOI: 10.1016/s0021-9258(19)39699-1  0.415
1989 Casciola LAF, Grant KI, Gevers W, Coetzee GA, Van Der Westhuyzen DR. Low-density-lipoprotein receptors in human fibroblasts are not degraded in lysosomes Biochemical Journal. 262: 681-683. PMID 2803276  0.451
1989 Leitersdorf E, Van Der Westhuyzen DR, Coetzee GA, Hobbs HH. Two common low density lipoprotein receptor gene mutations cause familial hypercholesterolemia in Afrikaners Journal of Clinical Investigation. 84: 954-961. PMID 2569482  0.312
1988 Dawson PA, Hofmann SL, van der Westhuyzen DR, Südhof TC, Brown MS, Goldstein JL. Sterol-dependent repression of low density lipoprotein receptor promoter mediated by 16-base pair sequence adjacent to binding site for transcription factor Sp1. The Journal of Biological Chemistry. 263: 3372-9. PMID 3277969  0.327
1988 Leitersdorf E, Hobbs HH, Fourie AM, Jacobs M, Van der Westhuyzen DR, Coetzee GA. Deletion in the first cysteine-rich repeat of low density lipoprotein receptor impairs its transport but not lipoprotein binding in fibroblasts from a subject with familial hypercholesterolemia Proceedings of the National Academy of Sciences of the United States of America. 85: 7912-7916. PMID 3263645  0.446
1988 Fourie AM, Coetzee GA, Gevers W, Van der Westhuyzen DR. Two mutant low-density-lipoprotein receptors in Afrikaners slowly processed to surface forms exhibiting rapid degradation or functional heterogeneity Biochemical Journal. 255: 411-415. PMID 3202825  0.415
1987 Südhof TC, Van der Westhuyzen DR, Goldstein JL, Brown MS, Russell DW. Three direct repeats and a TATA-like sequence are required for regulated expression of the human low density lipoprotein receptor gene. The Journal of Biological Chemistry. 262: 10773-9. PMID 3611089  0.334
1987 Shephard EG, De Beer FC, De Beer MC, Jeenah MS, Coetzee GA, Van Der Westhuyzen DR. Neutrophil association and degradation of normal and acute-phase high-density lipoprotein 3 Biochemical Journal. 248: 919-926. PMID 2449174  0.415
1986 Coetzee GA, Strachan AF, van der Westhuyzen DR, Hoppe HC, Jeenah MS, de Beer FC. Serum amyloid A-containing human high density lipoprotein 3. Density, size, and apolipoprotein composition. Journal of Biological Chemistry. 261: 9644-9651. DOI: 10.1016/s0021-9258(18)67562-3  0.306
1985 Aulinskas TH, Oram JF, Bierman EL, Coetzee GA, Gevers W, van der Westhuyzen DR. Retro-endocytosis of low density lipoprotein by cultured human skin fibroblasts Arteriosclerosis. 5: 45-54. PMID 2578279 DOI: 10.1161/01.Atv.5.1.45  0.526
1984 Van der Westhuyzen DR, Coetzee GA, Demasius IPC. Low density lipoprotein receptor mutations in South African homozygous familial hypercholesterolemic patients Arteriosclerosis. 4: 238-247. PMID 6324732 DOI: 10.1161/01.Atv.4.3.238  0.457
1984 Higgs DW, van der Westhuyzen DR, Gevers W, Coetzee GA, Stein O, Stein Y. In vitro metabolism of LDL labeled with a nondegradable cholesteryl ester analogue Arteriosclerosis. 4: 208-213. PMID 6324730 DOI: 10.1161/01.Atv.4.3.208  0.389
1983 Aulinskas TH, Van der Westhuyzen DR, Coetzee GA. Ascorbate increases the number of low density lipoprotein receptors in cultured arterial smooth muscle cells Atherosclerosis. 47: 159-171. PMID 6307323 DOI: 10.1016/0021-9150(83)90152-1  0.482
1982 Aulinskas TH, Coetzee GA, Gevers W, van der Westhuyzen DR. Evidence that recycling of low density lipoprotein receptors does not depend on delivery of receptors to lysosomes Biochemical and Biophysical Research Communications. 107: 1551-1558. PMID 6291535 DOI: 10.1016/S0006-291X(82)80176-9  0.474
1982 Coetzee GA, van der Westhuyzen DR, Berger GMB, Henderson HE, Gevers W. Low density lipoprotein metabolism in cultured fibroblasts from a new group of patients presenting clinically with homozygous familial hypercholesterolemia Arteriosclerosis. 2: 303-311. PMID 6287984 DOI: 10.1161/01.Atv.2.4.303  0.509
1981 Aulinskas TH, Van Der Westhuyzen DR, Bierman EL, Gevers W, Coetzee GA. Retro-endocytosis of low density lipoprotein by cultured bovine aortic smooth muscle cells Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 664: 255-265. PMID 7248324 DOI: 10.1016/0005-2760(81)90048-5  0.454
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