Judy A. Siuciak - Publications

Affiliations: 
Pfizer, Trujui, Buenos Aires, Argentina 
Area:
BDNF, phosphodiesterases

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Siuciak JA, Pitts WJ. Phosphodiesterase Inhibitors as a Novel Therapeutic Approach for Schizophrenia Targets and Emerging Therapies For Schizophrenia. 85-113. DOI: 10.1002/9781118309421.ch4  0.48
2011 Zhang L, Brodney MA, Candler J, Doran AC, Duplantier AJ, Efremov IV, Evrard E, Kraus K, Ganong AH, Haas JA, Hanks AN, Jenza K, Lazzaro JT, Maklad N, McCarthy SA, ... ... Siuciak JA, et al. 1-[(1-methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 positive allosteric modulators for the treatment of psychosis. Journal of Medicinal Chemistry. 54: 1724-39. PMID 21366332 DOI: 10.1021/jm101414h  0.48
2009 Duplantier AJ, Efremov I, Candler J, Doran AC, Ganong AH, Haas JA, Hanks AN, Kraus KG, Lazzaro JT, Lu J, Maklad N, McCarthy SA, O'Sullivan TJ, Rogers BN, Siuciak JA, et al. 3-Benzyl-1,3-oxazolidin-2-ones as mGluR2 positive allosteric modulators: Hit-to lead and lead optimization. Bioorganic & Medicinal Chemistry Letters. 19: 2524-9. PMID 19328692 DOI: 10.1016/j.bmcl.2009.03.032  0.48
2008 Siuciak JA. The role of phosphodiesterases in schizophrenia : therapeutic implications. Cns Drugs. 22: 983-93. PMID 18998737 DOI: 10.2165/0023210-200822120-00002  0.48
2008 Schmidt CJ, Chapin DS, Cianfrogna J, Corman ML, Hajos M, Harms JF, Hoffman WE, Lebel LA, McCarthy SA, Nelson FR, Proulx-LaFrance C, Majchrzak MJ, Ramirez AD, Schmidt K, Seymour PA, ... Siuciak JA, et al. Preclinical characterization of selective phosphodiesterase 10A inhibitors: a new therapeutic approach to the treatment of schizophrenia. The Journal of Pharmacology and Experimental Therapeutics. 325: 681-90. PMID 18287214 DOI: 10.1124/jpet.107.132910  0.48
2008 Siuciak JA, McCarthy SA, Chapin DS, Martin AN, Harms JF, Schmidt CJ. Behavioral characterization of mice deficient in the phosphodiesterase-10A (PDE10A) enzyme on a C57/Bl6N congenic background. Neuropharmacology. 54: 417-27. PMID 18061215 DOI: 10.1016/j.neuropharm.2007.10.009  0.48
2008 Siuciak JA, McCarthy SA, Chapin DS, Martin AN. Behavioral and neurochemical characterization of mice deficient in the phosphodiesterase-4B (PDE4B) enzyme. Psychopharmacology. 197: 115-26. PMID 18060387 DOI: 10.1007/s00213-007-1014-6  0.48
2007 Siuciak JA, Strick CA. Phosphodiesterase 10A inhibitors as a novel therapeutic approach for schizophrenia. Expert Opinion On Drug Discovery. 2: 1001-9. PMID 23484819 DOI: 10.1517/17460441.2.7.1001  0.48
2007 Siuciak JA, McCarthy SA, Chapin DS, Reed TM, Vorhees CV, Repaske DR. Behavioral and neurochemical characterization of mice deficient in the phosphodiesterase-1B (PDE1B) enzyme. Neuropharmacology. 53: 113-24. PMID 17559891 DOI: 10.1016/j.neuropharm.2007.04.009  0.48
2007 Siuciak JA, McCarthy SA, Martin AN, Chapin DS, Stock J, Nadeau DM, Kantesaria S, Bryce-Pritt D, McLean S. Disruption of the neurokinin-3 receptor (NK3) in mice leads to cognitive deficits. Psychopharmacology. 194: 185-95. PMID 17558564 DOI: 10.1007/s00213-007-0828-6  0.48
2007 Siuciak JA, Chapin DS, McCarthy SA, Martin AN. Antipsychotic profile of rolipram: efficacy in rats and reduced sensitivity in mice deficient in the phosphodiesterase-4B (PDE4B) enzyme. Psychopharmacology. 192: 415-24. PMID 17333137 DOI: 10.1007/s00213-007-0727-x  0.48
2007 Siuciak JA, Chapin DS, McCarthy SA, Guanowsky V, Brown J, Chiang P, Marala R, Patterson T, Seymour PA, Swick A, Iredale PA. CP-809,101, a selective 5-HT2C agonist, shows activity in animal models of antipsychotic activity. Neuropharmacology. 52: 279-90. PMID 16949622 DOI: 10.1016/j.neuropharm.2006.07.024  0.48
2006 Siuciak JA, Chapin DS, Harms JF, Lebel LA, McCarthy SA, Chambers L, Shrikhande A, Wong S, Menniti FS, Schmidt CJ. Inhibition of the striatum-enriched phosphodiesterase PDE10A: a novel approach to the treatment of psychosis. Neuropharmacology. 51: 386-96. PMID 16780899 DOI: 10.1016/j.neuropharm.2006.04.013  0.48
2006 Siuciak JA, McCarthy SA, Chapin DS, Fujiwara RA, James LC, Williams RD, Stock JL, McNeish JD, Strick CA, Menniti FS, Schmidt CJ. Genetic deletion of the striatum-enriched phosphodiesterase PDE10A: evidence for altered striatal function. Neuropharmacology. 51: 374-85. PMID 16769090 DOI: 10.1016/j.neuropharm.2006.01.012  0.48
2006 Siuciak JA, Strick CA. Treating neuropsychiatric disorders with PDE10A inhibitors Drug Discovery Today: Therapeutic Strategies. 3: 527-532. DOI: 10.1016/j.ddstr.2006.10.012  0.48
2004 Siuciak JA, Fujiwara RA. The activity of pramipexole in the mouse forced swim test is mediated by D2 rather than D3 receptors. Psychopharmacology. 175: 163-9. PMID 14985923 DOI: 10.1007/s00213-004-1809-7  0.48
2001 MacQueen GM, Ramakrishnan K, Croll SD, Siuciak JA, Yu G, Young LT, Fahnestock M. Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression. Behavioral Neuroscience. 115: 1145-53. PMID 11584927 DOI: 10.1037/0735-7044.115.5.1145  0.48
1999 Vaidya VA, Siuciak JA, Du F, Duman RS. Hippocampal mossy fiber sprouting induced by chronic electroconvulsive seizures. Neuroscience. 89: 157-66. PMID 10051225 DOI: 10.1016/S0306-4522(98)00289-9  0.48
1998 Croll SD, Chesnutt CR, Rudge JS, Acheson A, Ryan TE, Siuciak JA, DiStefano PS, Wiegand SJ, Lindsay RM. Co-infusion with a TrkB-Fc receptor body carrier enhances BDNF distribution in the adult rat brain. Experimental Neurology. 152: 20-33. PMID 9682009 DOI: 10.1006/exnr.1998.6836  0.48
1998 Siuciak JA, Clark MS, Rind HB, Whittemore SR, Russo AF. BDNF induction of tryptophan hydroxylase mRNA levels in the rat brain. Journal of Neuroscience Research. 52: 149-58. PMID 9579405 DOI: 10.1002/(SICI)1097-4547(19980415)52:2<149::AID-JNR3>3.0.CO;2-A  0.48
1998 Cliffer KD, Siuciak JA, Carson SR, Radley HE, Park JS, Lewis DR, Zlotchenko E, Nguyen T, Garcia K, Tonra JR, Stambler N, Cedarbaum JM, Bodine SC, Lindsay RM, DiStefano PS. Physiological characterization of Taxol-induced large-fiber sensory neuropathy in the rat. Annals of Neurology. 43: 46-55. PMID 9450768 DOI: 10.1002/ana.410430111  0.48
1997 Frank L, Wiegand SJ, Siuciak JA, Lindsay RM, Rudge JS. Effects of BDNF infusion on the regulation of TrkB protein and message in adult rat brain. Experimental Neurology. 145: 62-70. PMID 9184109 DOI: 10.1006/exnr.1997.6440  0.48
1997 Siuciak JA, Lewis DR, Wiegand SJ, Lindsay RM. Antidepressant-like effect of brain-derived neurotrophic factor (BDNF). Pharmacology, Biochemistry, and Behavior. 56: 131-7. PMID 8981620 DOI: 10.1016/S0091-3057(96)00169-4  0.48
1996 Siuciak JA, Boylan C, Fritsche M, Altar CA, Lindsay RM. BDNF increases monoaminergic activity in rat brain following intracerebroventricular or intraparenchymal administration. Brain Research. 710: 11-20. PMID 8963648 DOI: 10.1016/0006-8993(95)01289-3  0.48
1996 Larson-Prior LJ, Siuciak JA, Dubocovich ML. Localization of 2-[125I]iodomelatonin binding sites in visual areas of the turtle brain. European Journal of Pharmacology. 297: 181-5. PMID 8851181  0.48
1996 Celada P, Siuciak JA, Tran TM, Altar CA, Tepper JM. Local infusion of brain-derived neurotrophic factor modifies the firing pattern of dorsal raphé serotonergic neurons. Brain Research. 712: 293-8. PMID 8814905 DOI: 10.1016/0006-8993(95)01469-1  0.48
1995 Mamounas LA, Blue ME, Siuciak JA, Altar CA. Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 7929-39. PMID 8613731  0.48
1995 Siuciak JA, Wong V, Pearsall D, Wiegand SJ, Lindsay RM. BDNF produces analgesia in the formalin test and modifies neuropeptide levels in rat brain and spinal cord areas associated with nociception. The European Journal of Neuroscience. 7: 663-70. PMID 7620617  0.48
1994 Altar CA, Siuciak JA, Wright P, Ip NY, Lindsay RM, Wiegand SJ. In situ hybridization of trkB and trkC receptor mRNA in rat forebrain and association with high-affinity binding of [125I]BDNF, [125I]NT-4/5 and [125I]NT-3. The European Journal of Neuroscience. 6: 1389-405. PMID 8000564  0.48
1994 Krause DN, Siuciak JA, Dubocovich ML. Unilateral optic nerve transection decreases 2-[125I]-iodomelatonin binding in retinorecipient areas and visual pathways of chick brain. Brain Research. 654: 63-74. PMID 7982099 DOI: 10.1016/0006-8993(94)91571-7  0.48
1994 Siuciak JA, Altar CA, Wiegand SJ, Lindsay RM. Antinociceptive effect of brain-derived neurotrophic factor and neurotrophin-3. Brain Research. 633: 326-30. PMID 7511037 DOI: 10.1016/0006-8993(94)91556-3  0.48
1993 Siuciak JA, Dubocovich ML. Effect of pinealectomy and the light/dark cycle on 2-[125I]iodomelatonin binding in the chick optic tectum. Cellular and Molecular Neurobiology. 13: 193-202. PMID 8242684 DOI: 10.1007/BF00733749  0.48
1992 Siuciak JA, Gamache PH, Dubocovich ML. Monoamines and their precursors and metabolites in the chicken brain, pineal, and retina: regional distribution and day/night variations. Journal of Neurochemistry. 58: 722-9. PMID 1729412  0.48
1992 Juorio AV, Dubocovich ML, Siuciak JA, Gamache PH. Avian brain epinephrine and 5-hydroxytryptamine: Is it still a matter of controversy? Journal of Neurochemistry. 59: 387-388. PMID 1613512 DOI: 10.1111/j.1471-4159.1992.tb08917.x  0.48
1992 Krause DN, Siuciak JA, Dubocovich ML. Optic nerve transection decreases 2-[125I]iodomelatonin binding in the chick optic tectum. Brain Research. 590: 325-8. PMID 1422841 DOI: 10.1016/0006-8993(92)91115-U  0.48
1991 Stanton TL, Siuciak JA, Dubocovich ML, Krause DN. The area of 2-[125I] iodomelatonin binding in the pars tuberalis of the ground squirrel is decreased during hibernation. Brain Research. 557: 285-8. PMID 1660755 DOI: 10.1016/0006-8993(91)90145-L  0.48
1991 Siuciak JA, Krause DN, Dubocovich ML. Quantitative pharmacological analysis of 2-125I-iodomelatonin binding sites in discrete areas of the chicken brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 2855-64. PMID 1652626  0.48
1990 Siuciak JA, Fang JM, Dubocovich ML. Autoradiographic localization of 2-[125I]iodomelatonin binding sites in the brains of C3H/HeN and C57BL/6J strains of mice. European Journal of Pharmacology. 180: 387-90. PMID 2365011 DOI: 10.1016/0014-2999(90)90328-4  0.48
1990 Dubocovich ML, Siuciak JA, Krause DN. Localization of high affinity melatonin receptor sites in chicken brain: Effect of temperature and guanine nucleotides European Journal of Pharmacology. 183: 2180. DOI: 10.1016/0014-2999(90)93707-W  0.48
1989 Siuciak JA, Advokat C. Antinociceptive effect of intrathecal morphine in tolerant and nontolerant spinal rats. Pharmacology, Biochemistry, and Behavior. 34: 445-52. PMID 2623001 DOI: 10.1016/0091-3057(89)90539-X  0.48
1989 Siuciak JA, Advokat C. The synergistic effect of concurrent spinal and supraspinal opiate agonisms is reduced by both nociceptive and morphine pretreatment. Pharmacology, Biochemistry, and Behavior. 34: 265-73. PMID 2622981 DOI: 10.1016/0091-3057(89)90310-9  0.48
1987 Siuciak JA, Advokat C. Tolerance to morphine microinjections in the periaqueductal gray (PAG) induces tolerance to systemic, but not intrathecal morphine. Brain Research. 424: 311-9. PMID 3676830 DOI: 10.1016/0006-8993(87)91476-4  0.48
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