Patrick J. Mulholland, Ph.D. - Publications

Affiliations: 
Medical University of South Carolina, Charleston, SC, United States 
Area:
Experimental Psychology

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cannady R, Rinker JA, Nimitvilai S, Woodward JJ, Mulholland PJ. Correction to: Chronic Alcohol, Intrinsic Excitability, and Potassium Channels: Neuroadaptations and Drinking Behavior. Handbook of Experimental Pharmacology. PMID 30810861 DOI: 10.1007/164_2018_192  0.76
2018 Haun HL, Griffin WC, Lopez MF, Solomon MG, Mulholland PJ, Woodward JJ, McGinty JF, Ron D, Becker HC. Increasing Brain-Derived Neurotrophic Factor (BDNF) in medial prefrontal cortex selectively reduces excessive drinking in ethanol dependent mice. Neuropharmacology. 140: 35-42. PMID 30056122 DOI: 10.1016/j.neuropharm.2018.07.031  0.76
2018 McGuier NS, Rinker JA, Cannady R, Fulmer DB, Jones SR, Hoffman M, Mulholland PJ. Identification and validation of midbrain Kcnq4 regulation of heavy alcohol consumption in rodents. Neuropharmacology. PMID 29775679 DOI: 10.1016/j.neuropharm.2018.05.020  0.64
2018 Cannady R, Rinker JA, Nimitvilai S, Woodward JJ, Mulholland PJ. Chronic Alcohol, Intrinsic Excitability, and Potassium Channels: Neuroadaptations and Drinking Behavior. Handbook of Experimental Pharmacology. PMID 29374839 DOI: 10.1007/164_2017_90  0.76
2017 Rinker JA, Mulholland PJ. Promising pharmacogenetic targets for treating alcohol use disorder: evidence from preclinical models. Pharmacogenomics. PMID 28346058 DOI: 10.2217/pgs-2016-0193  0.64
2017 Cannady R, McGonigal JT, Newsom RJ, Woodward JJ, Mulholland PJ, Gass JT. Prefrontal cortex KCa2 channels regulate mGlu5-dependent plasticity and extinction of alcohol-seeking behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28320841 DOI: 10.1523/JNEUROSCI.2873-16.2017  0.76
2017 den Hartog CR, Gilstrap M, Eaton B, Lench DH, Mulholland PJ, Homanics GE, Woodward JJ. Effects of Repeated Ethanol Exposures on NMDA Receptor Expression and Locomotor Sensitization in Mice Expressing Ethanol Resistant NMDA Receptors. Frontiers in Neuroscience. 11: 84. PMID 28270746 DOI: 10.3389/fnins.2017.00084  0.76
2017 Nimitvilai S, Uys JD, Woodward JJ, Randall PK, Ball LE, Williams RW, Jones BC, Lu L, Grant KA, Mulholland PJ. Orbitofrontal neuroadaptations and cross-species synaptic biomarkers in heavy drinking macaques. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28270566 DOI: 10.1523/JNEUROSCI.0133-17.2017  0.76
2017 Nimitvilai S, Lopez MF, Mulholland PJ, Woodward JJ. Ethanol Dependence Abolishes Monoamine and GIRK (Kir3) Channel Inhibition of Orbitofrontal Cortex Excitability. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28139680 DOI: 10.1038/npp.2017.22  0.76
2016 Trantham-Davidson H, Centanni SW, Garr SC, New NN, Mulholland PJ, Gass JT, Glover EJ, Floresco SB, Crews FT, Krishnan HR, Pandey SC, Chandler LJ. Binge-Like Alcohol Exposure during Adolescence Disrupts Dopaminergic Neurotransmission in the Adult Prelimbic Cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27620551 DOI: 10.1038/npp.2016.190  0.68
2016 Rinker JA, Fulmer DB, Trantham-Davidson H, Smith ML, Williams RW, Lopez MF, Randall PK, Chandler LJ, Miles MF, Becker HC, Mulholland PJ. Differential potassium channel gene regulation in BXD mice reveals novel targets for pharmacogenetic therapies to reduce heavy alcohol drinking. Alcohol (Fayetteville, N.Y.). PMID 27432260 DOI: 10.1016/j.alcohol.2016.05.007  0.76
2016 Mulholland PJ, Chandler LJ, Kalivas PW. Signals from the Fourth Dimension Regulate Drug Relapse. Trends in Neurosciences. PMID 27173064 DOI: 10.1016/j.tins.2016.04.007  0.92
2016 Spencer KB, Mulholland PJ, Chandler LJ. FMRP Mediates Chronic Ethanol-Induced Changes in NMDA, Kv4.2, and KChIP3 Expression in the Hippocampus. Alcoholism, Clinical and Experimental Research. PMID 27147118 DOI: 10.1111/acer.13060  0.92
2015 Nimitvilai S, Lopez MF, Mulholland PJ, Woodward JJ. Chronic Intermittent Ethanol Exposure Enhances the Excitability and Synaptic Plasticity of Lateral Orbitofrontal Cortex Neurons and Induces a Tolerance to the Acute Inhibitory Actions of Ethanol. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26286839 DOI: 10.1038/npp.2015.250  0.92
2015 McGuier NS, Griffin WC, Gass JT, Padula AE, Chesler EJ, Mulholland PJ. Kv7 channels in the nucleus accumbens are altered by chronic drinking and are targets for reducing alcohol consumption. Addiction Biology. PMID 26104325 DOI: 10.1111/adb.12279  0.48
2015 Samantaray S, Knaryan VH, Patel KS, Mulholland PJ, Becker HC, Banik NL. Chronic intermittent ethanol induced axon and myelin degeneration is attenuated by calpain inhibition. Brain Research. 1622: 7-21. PMID 26100335 DOI: 10.1016/j.brainres.2015.06.014  0.92
2015 Uys JD, McGuier NS, Gass JT, Griffin WC, Ball LE, Mulholland PJ. Chronic intermittent ethanol exposure and withdrawal leads to adaptations in nucleus accumbens core postsynaptic density proteome and dendritic spines. Addiction Biology. PMID 25787124 DOI: 10.1111/adb.12238  0.92
2015 McGuier NS, Padula AE, Mulholland PJ, Chandler LJ. Homer2 deletion alters dendritic spine morphology but not alcohol-associated adaptations in GluN2B-containing N-methyl-D-aspartate receptors in the nucleus accumbens. Frontiers in Pharmacology. 6: 28. PMID 25755642 DOI: 10.3389/fphar.2015.00028  0.92
2015 Padula AE, Griffin WC, Lopez MF, Nimitvilai S, Cannady R, McGuier NS, Chesler EJ, Miles MF, Williams RW, Randall PK, Woodward JJ, Becker HC, Mulholland PJ. KCNN Genes that Encode Small-Conductance Ca(2+)-Activated K(+) Channels Influence Alcohol and Drug Addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1928-39. PMID 25662840 DOI: 10.1038/npp.2015.42  0.92
2015 Mulholland PJ, Spencer KB, Hu W, Kroener S, Chandler LJ. Neuroplasticity of A-type potassium channel complexes induced by chronic alcohol exposure enhances dendritic calcium transients in hippocampus. Psychopharmacology. 232: 1995-2006. PMID 25510858 DOI: 10.1007/s00213-014-3835-4  0.92
2015 McGuier NS, Padula AE, Lopez MF, Woodward JJ, Mulholland PJ. Withdrawal from chronic intermittent alcohol exposure increases dendritic spine density in the lateral orbitofrontal cortex of mice. Alcohol (Fayetteville, N.Y.). 49: 21-7. PMID 25468278 DOI: 10.1016/j.alcohol.2014.07.017  0.92
2015 Mcguier NS, Griffin WC, Gass JT, Padula AE, Chesler EJ, Mulholland PJ. Kv7 channels in the nucleus accumbens are altered by chronic drinking and are targets for reducing alcohol consumption Addiction Biology. DOI: 10.1111/adb.12279  0.92
2014 Centanni SW, Teppen T, Risher ML, Fleming RL, Moss JL, Acheson SK, Mulholland PJ, Pandey SC, Chandler LJ, Swartzwelder HS. Adolescent alcohol exposure alters GABAA receptor subunit expression in adult hippocampus. Alcoholism, Clinical and Experimental Research. 38: 2800-8. PMID 25421517 DOI: 10.1111/acer.12562  0.92
2014 Becker HC, Mulholland PJ. Neurochemical mechanisms of alcohol withdrawal. Handbook of Clinical Neurology. 125: 133-56. PMID 25307573 DOI: 10.1016/B978-0-444-62619-6.00009-4  0.92
2014 Uys JD, Mulholland PJ, Townsend DM. Glutathione and redox signaling in substance abuse. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 68: 799-807. PMID 25027386 DOI: 10.1016/j.biopha.2014.06.001  0.92
2014 Trantham-Davidson H, Burnett EJ, Gass JT, Lopez MF, Mulholland PJ, Centanni SW, Floresco SB, Chandler LJ. Chronic alcohol disrupts dopamine receptor activity and the cognitive function of the medial prefrontal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3706-18. PMID 24599469 DOI: 10.1523/JNEUROSCI.0623-13.2014  0.92
2013 Konadhode RR, Pelluru D, Blanco-Centurion C, Zayachkivsky A, Liu M, Uhde T, Glen WB, van den Pol AN, Mulholland PJ, Shiromani PJ. Optogenetic stimulation of MCH neurons increases sleep. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 10257-63. PMID 23785141 DOI: 10.1523/JNEUROSCI.1225-13.2013  0.92
2013 Badanich KA, Mulholland PJ, Beckley JT, Trantham-Davidson H, Woodward JJ. Ethanol reduces neuronal excitability of lateral orbitofrontal cortex neurons via a glycine receptor dependent mechanism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1176-88. PMID 23314219 DOI: 10.1038/npp.2013.12  0.92
2013 Jung Y, Mulholland PJ, Wiseman SL, Chandler LJ, Picciotto MR. Constitutive knockout of the membrane cytoskeleton protein beta adducin decreases mushroom spine density in the nucleus accumbens but does not prevent spine remodeling in response to cocaine. The European Journal of Neuroscience. 37: 1-9. PMID 23106536 DOI: 10.1111/ejn.12037  0.92
2012 Mulholland PJ, Jordan BA, Chandler LJ. Chronic ethanol up-regulates the synaptic expression of the nuclear translational regulatory protein AIDA-1 in primary hippocampal neurons. Alcohol (Fayetteville, N.Y.). 46: 569-76. PMID 22703994 DOI: 10.1016/j.alcohol.2012.04.004  0.92
2012 Kroener S, Mulholland PJ, New NN, Gass JT, Becker HC, Chandler LJ. Chronic alcohol exposure alters behavioral and synaptic plasticity of the rodent prefrontal cortex. Plos One. 7: e37541. PMID 22666364 DOI: 10.1371/journal.pone.0037541  0.92
2012 Roberto M, Kash TL, Mulholland PJ, Marty VN, Gilpin NW, Walker BM. Introduction to Young Investigator Award Symposium: Symposium XII: Young Investigator Award. Alcohol (Fayetteville, N.Y.). 46: 301-2. PMID 22541586 DOI: 10.1016/j.alcohol.2012.04.001  0.92
2012 Mulholland PJ. K(Ca)2 channels: novel therapeutic targets for treating alcohol withdrawal and escalation of alcohol consumption. Alcohol (Fayetteville, N.Y.). 46: 309-15. PMID 22464787 DOI: 10.1016/j.alcohol.2011.11.002  0.92
2012 Prendergast MA, Mulholland PJ. Glucocorticoid and polyamine interactions in the plasticity of glutamatergic synapses that contribute to ethanol-associated dependence and neuronal injury. Addiction Biology. 17: 209-23. PMID 21967628 DOI: 10.1111/j.1369-1600.2011.00375.x  0.92
2012 Pava MJ, Blake EM, Green ST, Mizroch BJ, Mulholland PJ, Woodward JJ. Tolerance to cannabinoid-induced behaviors in mice treated chronically with ethanol. Psychopharmacology. 219: 137-47. PMID 21701813 DOI: 10.1007/s00213-011-2387-0  0.92
2012 Gorelova N, Mulholland PJ, Chandler LJ, Seamans JK. The glutamatergic component of the mesocortical pathway emanating from different subregions of the ventral midbrain. Cerebral Cortex (New York, N.Y. : 1991). 22: 327-36. PMID 21666135 DOI: 10.1093/cercor/bhr107  0.92
2011 Badanich KA, Doremus-Fitzwater TL, Mulholland PJ, Randall PK, Delpire E, Becker HC. NR2B-deficient mice are more sensitive to the locomotor stimulant and depressant effects of ethanol. Genes, Brain, and Behavior. 10: 805-16. PMID 21762461 DOI: 10.1111/j.1601-183X.2011.00720.x  0.92
2011 Mulholland PJ, Becker HC, Woodward JJ, Chandler LJ. Small conductance calcium-activated potassium type 2 channels regulate alcohol-associated plasticity of glutamatergic synapses. Biological Psychiatry. 69: 625-32. PMID 21056409 DOI: 10.1016/j.biopsych.2010.09.025  0.92
2010 Mulholland PJ, Chandler LJ. Inhibition of glutamate transporters couples to Kv4.2 dephosphorylation through activation of extrasynaptic NMDA receptors. Neuroscience. 165: 130-7. PMID 19850106 DOI: 10.1016/j.neuroscience.2009.10.024  0.92
2010 Butler TR, Self RL, Smith KJ, Sharrett-Field LJ, Berry JN, Littleton JM, Pauly JR, Mulholland PJ, Prendergast MA. Selective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-D-asparate-type glutamate receptors. Neuroscience. 165: 525-34. PMID 19837138 DOI: 10.1016/j.neuroscience.2009.10.018  0.92
2009 Mulholland PJ, Hopf FW, Bukiya AN, Martin GE, Liu J, Dopico AM, Bonci A, Treistman SN, Chandler LJ. Sizing up ethanol-induced plasticity: the role of small and large conductance calcium-activated potassium channels. Alcoholism, Clinical and Experimental Research. 33: 1125-35. PMID 19389201 DOI: 10.1111/j.1530-0277.2009.00936.x  0.92
2009 Mulholland PJ, Carpenter-Hyland EP, Woodward JJ, Chandler LJ. Ethanol disrupts NMDA receptor and astroglial EAAT2 modulation of Kv2.1 potassium channels in hippocampus. Alcohol (Fayetteville, N.Y.). 43: 45-50. PMID 19185209 DOI: 10.1016/j.alcohol.2008.10.001  0.92
2008 Mulholland PJ, Carpenter-Hyland EP, Hearing MC, Becker HC, Woodward JJ, Chandler LJ. Glutamate transporters regulate extrasynaptic NMDA receptor modulation of Kv2.1 potassium channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8801-9. PMID 18753382 DOI: 10.1523/JNEUROSCI.2405-08.2008  0.92
2008 Barron S, Mulholland PJ, Littleton JM, Prendergast MA. Age and gender differences in response to neonatal ethanol withdrawal and polyamine challenge in organotypic hippocampal cultures. Alcoholism, Clinical and Experimental Research. 32: 929-36. PMID 18445110 DOI: 10.1111/j.1530-0277.2008.00649.x  0.92
2008 Mulholland PJ, Luong NT, Woodward JJ, Chandler LJ. Brain-derived neurotrophic factor activation of extracellular signal-regulated kinase is autonomous from the dominant extrasynaptic NMDA receptor extracellular signal-regulated kinase shutoff pathway. Neuroscience. 151: 419-27. PMID 18055129 DOI: 10.1016/j.neuroscience.2007.11.001  0.92
2007 Mulholland PJ, Chandler LJ. The thorny side of addiction: adaptive plasticity and dendritic spines. Thescientificworldjournal. 7: 9-21. PMID 17982573 DOI: 10.1100/tsw.2007.247  0.92
2007 Mulholland PJ, Judson Chandler L. The plasticity of alcohol addiction suggests novel approaches to pharmacological intervention Translation of Addictions Science Into Practice. 103-122. DOI: 10.1016/B978-008044927-2/50055-9  0.92
2006 Mulholland PJ, Self RL, Hensley AK, Little HJ, Littleton JM, Prendergast MA. A 24 h corticosterone exposure exacerbates excitotoxic insult in rat hippocampal slice cultures independently of glucocorticoid receptor activation or protein synthesis. Brain Research. 1082: 165-72. PMID 16510135 DOI: 10.1016/j.brainres.2006.01.069  0.92
2005 Self RL, Smith KJ, Mulholland PJ, Prendergast MA. Ethanol exposure and withdrawal sensitizes the rat hippocampal CA1 pyramidal cell region to beta-amyloid (25-35)-induced cytotoxicity: NMDA receptor involvement. Alcoholism, Clinical and Experimental Research. 29: 2063-9. PMID 16340465 DOI: 10.1097/01.alc.0000187591.82039.b2  0.92
2005 Mulholland PJ, Stepanyan TD, Self RL, Hensley AK, Harris BR, Kowalski A, Littleton JM, Prendergast MA. Corticosterone and dexamethasone potentiate cytotoxicity associated with oxygen-glucose deprivation in organotypic cerebellar slice cultures. Neuroscience. 136: 259-67. PMID 16182452 DOI: 10.1016/j.neuroscience.2005.07.043  0.92
2005 Mulholland PJ, Self RL, Stepanyan TD, Little HJ, Littleton JM, Prendergast MA. Thiamine deficiency in the pathogenesis of chronic ethanol-associated cerebellar damage in vitro. Neuroscience. 135: 1129-39. PMID 16165302 DOI: 10.1016/j.neuroscience.2005.06.077  0.92
2005 Mulholland PJ, Self RL, Harris BR, Little HJ, Littleton JM, Prendergast MA. Corticosterone increases damage and cytosolic calcium accumulation associated with ethanol withdrawal in rat hippocampal slice cultures. Alcoholism, Clinical and Experimental Research. 29: 871-81. PMID 15897733 DOI: 10.1097/01.ALC.0000163509.27577.DA  0.92
2004 Self RL, Mulholland PJ, Harris BR, Nath A, Prendergast MA. Cytotoxic effects of exposure to the human immunodeficiency virus type 1 protein Tat in the hippocampus are enhanced by prior ethanol treatment. Alcoholism, Clinical and Experimental Research. 28: 1916-24. PMID 15608609 DOI: 10.1097/01.ALC.0000148108.93782.05  0.92
2004 Mulholland PJ, Self RL, Harris BR, Littleton JM, Prendergast MA. Choline exposure reduces potentiation of N-methyl-D-aspartate toxicity by corticosterone in the developing hippocampus. Brain Research. Developmental Brain Research. 153: 203-11. PMID 15527888 DOI: 10.1016/j.devbrainres.2004.08.008  0.92
2004 Mulholland PJ, Self RL, Harris BR, Littleton JM, Prendergast MA. (-)-nicotine ameliorates corticosterone's potentiation of N-methyl-d-aspartate receptor-mediated cornu ammonis 1 toxicity. Neuroscience. 125: 671-82. PMID 15099681 DOI: 10.1016/j.neuroscience.2004.02.007  0.92
2004 Self RL, Mulholland PJ, Nath A, Harris BR, Prendergast MA. The human immunodeficiency virus type-1 transcription factor Tat produces elevations in intracellular Ca2+ that require function of an N-methyl-D-aspartate receptor polyamine-sensitive site. Brain Research. 995: 39-45. PMID 14644469 DOI: 10.1016/j.brainres.2003.09.052  0.92
2003 Mulholland PJ, Harris BR, Wilkins LH, Self RL, Blanchard JA, Holley RC, Littleton JM, Prendergast MA. Opposing effects of ethanol and nicotine on hippocampal calbindin-D28k expression. Alcohol (Fayetteville, N.Y.). 31: 1-10. PMID 14615005 DOI: 10.1016/j.alcohol.2003.09.001  0.92
2003 Mulholland PJ, Prendergast MA. Transection of intrinsic polysynaptic pathways reduces N-methyl-D-aspartate neurotoxicity in hippocampal slice cultures. Neuroscience Research. 46: 369-76. PMID 12804798 DOI: 10.1016/S0168-0102(03)00102-0  0.92
2002 Prendergast MA, Rogers DT, Mulholland PJ, Littleton JM, Wilkins LH, Self RL, Nath A. Neurotoxic effects of the human immunodeficiency virus type-1 transcription factor Tat require function of a polyamine sensitive-site on the N-methyl-D-aspartate receptor. Brain Research. 954: 300-7. PMID 12414113 DOI: 10.1016/S0006-8993(02)03360-7  0.92
2002 Mulholland PJ, Prendergast MA. Post-insult exposure to (+/-) kavain potentiates N-methyl-D-aspartate toxicity in the developing hippocampus. Brain Research. 945: 106-13. PMID 12113957 DOI: 10.1016/S0006-8993(02)02745-2  0.92
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