David L. Brody - Publications

Affiliations: 
Neurology Washington University, Saint Louis, St. Louis, MO 

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sauerbeck AD, Gangolli M, Reitz SJ, Salyards MH, Kim SH, Hemingway C, Gratuze M, Makkapati T, Kerschensteiner M, Holtzman DM, Brody DL, Kummer TT. SEQUIN Multiscale Imaging of Mammalian Central Synapses Reveals Loss of Synaptic Connectivity Resulting from Diffuse Traumatic Brain Injury. Neuron. PMID 32392471 DOI: 10.1016/j.neuron.2020.04.012  0.44
2020 Jiang H, Esparza TJ, Kummer TT, Zhong H, Rettig J, Brody DL. Live Neuron High-Content Screening Reveals Synaptotoxic Activity in Alzheimer Mouse Model Homogenates. Scientific Reports. 10: 3412. PMID 32098978 DOI: 10.1038/s41598-020-60118-y  0.4
2018 Gangolli M, Benetatos J, Esparza TJ, Fountain EM, Seneviratne S, Brody D. Repetitive concussive and subconcussive injury in a human tau mouse model results in chronic cognitive dysfunction and disruption of white matter tracts, but not tau pathology. Journal of Neurotrauma. PMID 30136628 DOI: 10.1089/neu.2018.5700  0.4
2018 Esparza TJ, Gangolli M, Cairns NJ, Brody DL. Soluble amyloid-beta buffering by plaques in Alzheimer disease dementia versus high-pathology controls. Plos One. 13: e0200251. PMID 29979775 DOI: 10.1371/journal.pone.0200251  0.4
2017 Wildburger NC, Esparza TJ, LeDuc RD, Fellers RT, Thomas PM, Cairns NJ, Kelleher NL, Bateman RJ, Brody DL. Diversity of Amyloid-beta Proteoforms in the Alzheimer's Disease Brain. Scientific Reports. 7: 9520. PMID 28842697 DOI: 10.1038/s41598-017-10422-x  0.4
2017 Brody DL, Jiang H, Wildburger N, Esparza TJ. Non-canonical soluble amyloid-beta aggregates and plaque buffering: controversies and future directions for target discovery in Alzheimer's disease. Alzheimer's Research & Therapy. 9: 62. PMID 28818091 DOI: 10.1186/s13195-017-0293-3  0.4
2017 Lebois EP, Schroeder JP, Esparza TJ, Bridges TM, Lindsley CW, Conn PJ, Brody DL, Daniels JS, Levey AI. Disease-Modifying Effects of M1 Muscarinic Acetylcholine Receptor Activation in an Alzheimer's Disease Mouse Model. Acs Chemical Neuroscience. PMID 28230352 DOI: 10.1021/acschemneuro.6b00278  0.4
2016 Esparza TJ, Wildburger NC, Jiang H, Gangolli M, Cairns NJ, Bateman RJ, Brody DL. Soluble Amyloid-beta Aggregates from Human Alzheimer's Disease Brains. Scientific Reports. 6: 38187. PMID 27917876 DOI: 10.1038/srep38187  0.4
2016 Li Z, Oganesyan D, Mooney R, Rong X, Christensen MJ, Shahmanyan D, Perrigue PM, Benetatos J, Tsaturyan L, Aramburo S, Annala AJ, Lu Y, Najbauer J, Wu X, Barish ME, ... Brody DL, et al. L-MYC Expression Maintains Self-Renewal and Prolongs Multipotency of Primary Human Neural Stem Cells. Stem Cell Reports. PMID 27546534 DOI: 10.1016/j.stemcr.2016.07.013  0.92
2016 Parikh U, Williams M, Jacobs A, Pineda JA, Brody DL, Friess SH. Delayed Hypoxemia Following Traumatic Brain Injury Exacerbates White Matter Injury. Journal of Neuropathology and Experimental Neurology. PMID 27288907 DOI: 10.1093/jnen/nlw045  0.92
2015 Kummer TT, Magnoni S, MacDonald CL, Dikranian K, Milner E, Sorrell J, Conte V, Benetatos JJ, Zipfel GJ, Brody DL. Experimental subarachnoid haemorrhage results in multifocal axonal injury. Brain : a Journal of Neurology. PMID 26115676 DOI: 10.1093/brain/awv180  0.92
2015 Adam O, Mac Donald CL, Rivet D, Ritter J, May T, Barefield M, Duckworth J, LaBarge D, Asher D, Drinkwine B, Woods Y, Connor M, Brody DL. Clinical and imaging assessment of acute combat mild traumatic brain injury in Afghanistan. Neurology. PMID 26109715 DOI: 10.1212/WNL.0000000000001758  0.92
2015 Magnoni S, Mac Donald CL, Esparza TJ, Conte V, Sorrell J, Macrì M, Bertani G, Biffi R, Costa A, Sammons B, Snyder AZ, Shimony JS, Triulzi F, Stocchetti N, Brody DL. Quantitative assessments of traumatic axonal injury in human brain: concordance of microdialysis and advanced MRI. Brain : a Journal of Neurology. PMID 26084657 DOI: 10.1093/brain/awv152  0.92
2015 Mac Donald CL, Adam OR, Johnson AM, Nelson EC, Werner NJ, Rivet DJ, Brody DL. Acute post-traumatic stress symptoms and age predict outcome in military blast concussion. Brain : a Journal of Neurology. 138: 1314-26. PMID 25740219 DOI: 10.1093/brain/awv038  0.92
2015 Brody DL, Mac Donald CL, Shimony JS. Current and future diagnostic tools for traumatic brain injury: CT, conventional MRI, and diffusion tensor imaging. Handbook of Clinical Neurology. 127: 267-75. PMID 25702222 DOI: 10.1016/B978-0-444-52892-6.00017-9  0.92
2015 Bennett RE, Brody DL. Array tomography for the detection of non-dilated, injured axons in traumatic brain injury. Journal of Neuroscience Methods. 245: 25-36. PMID 25687633 DOI: 10.1016/j.jneumeth.2015.02.005  0.92
2015 Brody DL, Benetatos J, Bennett RE, Klemenhagen KC, Mac Donald CL. The pathophysiology of repetitive concussive traumatic brain injury in experimental models; new developments and open questions. Molecular and Cellular Neurosciences. 66: 91-98. PMID 25684677 DOI: 10.1016/j.mcn.2015.02.005  0.92
2015 Friess SH, Lapidus JB, Brody DL. Decompressive craniectomy reduces white matter injury after controlled cortical impact in mice. Journal of Neurotrauma. 32: 791-800. PMID 25557588 DOI: 10.1089/neu.2014.3564  0.92
2015 Solga AC, Pong WW, Walker J, Wylie T, Magrini V, Apicelli AJ, Griffith M, Griffith OL, Kohsaka S, Wu GF, Brody DL, Mardis ER, Gutmann DH. RNA-sequencing reveals oligodendrocyte and neuronal transcripts in microglia relevant to central nervous system disease. Glia. 63: 531-48. PMID 25258010 DOI: 10.1002/glia.22754  0.92
2014 Brody DL, Gross ML. The remarkable properties of amyloid-β derived from human Alzheimer's disease brain: swinging the streetlight. Brain : a Journal of Neurology. 137: 2874-5. PMID 25344080 DOI: 10.1093/brain/awu261  0.92
2014 Milner E, Holtzman JC, Friess S, Hartman RE, Brody DL, Han BH, Zipfel GJ. Endovascular perforation subarachnoid hemorrhage fails to cause Morris water maze deficits in the mouse. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34. PMID 24938403 DOI: 10.1038/jcbfm.2014.108  0.92
2014 Mac Donald CL, Johnson AM, Wierzechowski L, Kassner E, Stewart T, Nelson EC, Werner NJ, Zonies D, Oh J, Fang R, Brody DL. Prospectively assessed clinical outcomes in concussive blast vs nonblast traumatic brain injury among evacuated US military personnel. Jama Neurology. 71: 994-1002. PMID 24934200 DOI: 10.1001/jamaneurol.2014.1114  0.92
2014 Bennett RE, Brody DL. Acute reduction of microglia does not alter axonal injury in a mouse model of repetitive concussive traumatic brain injury. Journal of Neurotrauma. 31: 1647-63. PMID 24797413 DOI: 10.1089/neu.2013.3320  0.92
2014 MacDonald CL, Johnson AM, Nelson EC, Werner NJ, Fang R, Flaherty SF, Brody DL. Functional status after blast-plus-impact complex concussive traumatic brain injury in evacuated United States military personnel. Journal of Neurotrauma. 31: 889-98. PMID 24367929 DOI: 10.1089/neu.2013.3173  0.92
2014 Han K, Mac Donald CL, Johnson AM, Barnes Y, Wierzechowski L, Zonies D, Oh J, Flaherty S, Fang R, Raichle ME, Brody DL. Disrupted modular organization of resting-state cortical functional connectivity in U.S. military personnel following concussive 'mild' blast-related traumatic brain injury. Neuroimage. 84: 76-96. PMID 23968735 DOI: 10.1016/j.neuroimage.2013.08.017  0.92
2013 Klemenhagen KC, O'Brien SP, Brody DL. Repetitive concussive traumatic brain injury interacts with post-injury foot shock stress to worsen social and depression-like behavior in mice. Plos One. 8: e74510. PMID 24058581 DOI: 10.1371/journal.pone.0074510  0.92
2013 Guo D, Zeng L, Brody DL, Wong M. Rapamycin attenuates the development of posttraumatic epilepsy in a mouse model of traumatic brain injury. Plos One. 8: e64078. PMID 23691153 DOI: 10.1371/journal.pone.0064078  0.92
2013 Bennett RE, Esparza TJ, Lewis HA, Kim E, Mac Donald CL, Sullivan PM, Brody DL. Human apolipoprotein E4 worsens acute axonal pathology but not amyloid-β immunoreactivity after traumatic brain injury in 3xTG-AD mice. Journal of Neuropathology and Experimental Neurology. 72: 396-403. PMID 23584199 DOI: 10.1097/NEN.0b013e31828e24ab  0.92
2013 Mac Donald C, Johnson A, Cooper D, Malone T, Sorrell J, Shimony J, Parsons M, Snyder A, Raichle M, Fang R, Flaherty S, Russell M, Brody DL. Cerebellar white matter abnormalities following primary blast injury in US military personnel. Plos One. 8: e55823. PMID 23409052 DOI: 10.1371/journal.pone.0055823  0.92
2013 Esparza TJ, Zhao H, Cirrito JR, Cairns NJ, Bateman RJ, Holtzman DM, Brody DL. Amyloid-β oligomerization in Alzheimer dementia versus high-pathology controls. Annals of Neurology. 73: 104-19. PMID 23225543 DOI: 10.1002/ana.23748  0.92
2012 Jiang Y, Brody DL. Administration of COG1410 reduces axonal amyloid precursor protein immunoreactivity and microglial activation after controlled cortical impact in mice. Journal of Neurotrauma. 29: 2332-41. PMID 22676717 DOI: 10.1089/neu.2012.2362  0.92
2012 Willie JT, Lim MM, Bennett RE, Azarion AA, Schwetye KE, Brody DL. Controlled cortical impact traumatic brain injury acutely disrupts wakefulness and extracellular orexin dynamics as determined by intracerebral microdialysis in mice. Journal of Neurotrauma. 29: 1908-21. PMID 22607167 DOI: 10.1089/neu.2012.2404  0.92
2012 Bennett RE, Mac Donald CL, Brody DL. Diffusion tensor imaging detects axonal injury in a mouse model of repetitive closed-skull traumatic brain injury. Neuroscience Letters. 513: 160-5. PMID 22343314 DOI: 10.1016/j.neulet.2012.02.024  0.92
2012 Tran HT, Sanchez L, Brody DL. Inhibition of JNK by a peptide inhibitor reduces traumatic brain injury-induced tauopathy in transgenic mice. Journal of Neuropathology and Experimental Neurology. 71: 116-29. PMID 22249463 DOI: 10.1097/NEN.0b013e3182456aed  0.92
2012 Magnoni S, Esparza TJ, Conte V, Carbonara M, Carrabba G, Holtzman DM, Zipfel GJ, Stocchetti N, Brody DL. Tau elevations in the brain extracellular space correlate with reduced amyloid-β levels and predict adverse clinical outcomes after severe traumatic brain injury. Brain : a Journal of Neurology. 135: 1268-80. PMID 22116192 DOI: 10.1093/brain/awr286  0.92
2011 Tran HT, Sanchez L, Esparza TJ, Brody DL. Distinct temporal and anatomical distributions of amyloid-β and tau abnormalities following controlled cortical impact in transgenic mice. Plos One. 6: e25475. PMID 21980472 DOI: 10.1371/journal.pone.0025475  0.92
2011 Tran HT, LaFerla FM, Holtzman DM, Brody DL. Controlled cortical impact traumatic brain injury in 3xTg-AD mice causes acute intra-axonal amyloid-β accumulation and independently accelerates the development of tau abnormalities. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 9513-25. PMID 21715616 DOI: 10.1523/JNEUROSCI.0858-11.2011  0.92
2011 Shitaka Y, Tran HT, Bennett RE, Sanchez L, Levy MA, Dikranian K, Brody DL. Repetitive closed-skull traumatic brain injury in mice causes persistent multifocal axonal injury and microglial reactivity. Journal of Neuropathology and Experimental Neurology. 70: 551-67. PMID 21666502 DOI: 10.1097/NEN.0b013e31821f891f  0.92
2011 Mac Donald CL, Johnson AM, Cooper D, Nelson EC, Werner NJ, Shimony JS, Snyder AZ, Raichle ME, Witherow JR, Fang R, Flaherty SF, Brody DL. Detection of blast-related traumatic brain injury in U.S. military personnel. The New England Journal of Medicine. 364: 2091-100. PMID 21631321 DOI: 10.1056/NEJMoa1008069  0.92
2011 Zanier ER, Refai D, Zipfel GJ, Zoerle T, Longhi L, Esparza TJ, Spinner ML, Bateman RJ, Brody DL, Stocchetti N. Neurofilament light chain levels in ventricular cerebrospinal fluid after acute aneurysmal subarachnoid haemorrhage. Journal of Neurology, Neurosurgery, and Psychiatry. 82: 157-9. PMID 20571038 DOI: 10.1136/jnnp.2009.177667  0.92
2011 Brody DL, Mac Donald CL, Snyder AZ. The authors reply New England Journal of Medicine. 365: 860-861.  0.92
2010 Magnoni S, Brody DL. New perspectives on amyloid-beta dynamics after acute brain injury: moving between experimental approaches and studies in the human brain. Archives of Neurology. 67: 1068-73. PMID 20837849 DOI: 10.1001/archneurol.2010.214  0.92
2010 Haacke EM, Duhaime AC, Gean AD, Riedy G, Wintermark M, Mukherjee P, Brody DL, DeGraba T, Duncan TD, Elovic E, Hurley R, Latour L, Smirniotopoulos JG, Smith DH. Common data elements in radiologic imaging of traumatic brain injury. Journal of Magnetic Resonance Imaging : Jmri. 32: 516-43. PMID 20815050 DOI: 10.1002/jmri.22259  0.92
2010 Schwetye KE, Cirrito JR, Esparza TJ, Mac Donald CL, Holtzman DM, Brody DL. Traumatic brain injury reduces soluble extracellular amyloid-β in mice: a methodologically novel combined microdialysis-controlled cortical impact study. Neurobiology of Disease. 40: 555-64. PMID 20682338 DOI: 10.1016/j.nbd.2010.06.018  0.92
2010 Wirths O, Bethge T, Marcello A, Harmeier A, Jawhar S, Lucassen PJ, Multhaup G, Brody DL, Esparza T, Ingelsson M, Kalimo H, Lannfelt L, Bayer TA. Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer's disease cases. Journal of Neural Transmission (Vienna, Austria : 1996). 117: 85-96. PMID 19823761 DOI: 10.1007/s00702-009-0314-x  0.92
2009 Brody DL, Magnoni S, Schwetye KE, Spinner M, Esparza TJ, Stocchetti N, Zipfel GJ, Holtzman DM. Amyloid-β dynamics correlate with neurological status in the injured human brain 3rd International Conference On Bioinformatics and Biomedical Engineering, Icbbe 2009. DOI: 10.1109/ICBBE.2009.5162305  0.92
2008 MacDonald CL, Schwarze N, Vaishnavi SN, Epstein AA, Snyder AZ, Raichle ME, Shimony JS, Brody DL. Verbal memory deficit following traumatic brain injury: assessment using advanced MRI methods. Neurology. 71: 1199-201. PMID 18838668 DOI: 10.1212/01.wnl.0000327521.69520.7f  0.92
2008 Brody DL, Magnoni S, Schwetye KE, Spinner ML, Esparza TJ, Stocchetti N, Zipfel GJ, Holtzman DM. Amyloid-beta dynamics correlate with neurological status in the injured human brain. Science (New York, N.Y.). 321: 1221-4. PMID 18755980 DOI: 10.1126/science.1161591  0.92
2008 Brody DL, Holtzman DM. Active and passive immunotherapy for neurodegenerative disorders. Annual Review of Neuroscience. 31: 175-93. PMID 18352830 DOI: 10.1146/annurev.neuro.31.060407.125529  0.92
2007 Brody DL, Mac Donald C, Kessens CC, Yuede C, Parsadanian M, Spinner M, Kim E, Schwetye KE, Holtzman DM, Bayly PV. Electromagnetic controlled cortical impact device for precise, graded experimental traumatic brain injury. Journal of Neurotrauma. 24: 657-73. PMID 17439349 DOI: 10.1089/neu.2006.0011  0.92
2007 Mac Donald CL, Dikranian K, Song SK, Bayly PV, Holtzman DM, Brody DL. Detection of traumatic axonal injury with diffusion tensor imaging in a mouse model of traumatic brain injury. Experimental Neurology. 205: 116-31. PMID 17368446 DOI: 10.1016/j.expneurol.2007.01.035  0.92
2006 Brody DL, Holtzman DM. Morris water maze search strategy analysis in PDAPP mice before and after experimental traumatic brain injury. Experimental Neurology. 197: 330-40. PMID 16309676 DOI: 10.1016/j.expneurol.2005.10.020  0.92
2005 Brody DL, Aiyagari V, Shackleford AM, Diringer MN. Use of recombinant factor VIIa in patients with warfarin-associated intracranial hemorrhage. Neurocritical Care. 2: 263-7. PMID 16159073 DOI: 10.1385/NCC:2:3:263  0.92
2001 Colecraft HM, Brody DL, Yue DT. G-protein inhibition of N- and P/Q-type calcium channels: distinctive elementary mechanisms and their functional impact. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1137-47. PMID 11160384  0.92
2000 Brody DL, Yue DT. Release-independent short-term synaptic depression in cultured hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 2480-94. PMID 10729328  0.92
2000 Brody DL, Yue DT. Relief of G-protein inhibition of calcium channels and short-term synaptic facilitation in cultured hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 889-98. PMID 10648693  0.92
1998 Patil PG, Brody DL, Yue DT. Preferential closed-state inactivation of neuronal calcium channels. Neuron. 20: 1027-38. PMID 9620706 DOI: 10.1016/S0896-6273(00)80483-3  0.92
1997 Brody DL, Patil PG, Mulle JG, Snutch TP, Yue DT. Bursts of action potential waveforms relieve G-protein inhibition of recombinant P/Q-type Ca2+ channels in HEK 293 cells. The Journal of Physiology. 499: 637-44. PMID 9130160  0.92
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