Anne B. Young, MD PhD - Publications

Affiliations: 
Neurology Massachusetts General Hospital, Boston, MA 
 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Basal Ganglia, Glutamate Receptors, Huntington's Disease
Website:
http://www.mghmind.org/Faculty/young_anne.html

207 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Anderson KE, Eberly S, Groves M, Kayson E, Marder K, Young AB, Shoulson I. Risk Factors for Suicidal Ideation in People at Risk for Huntington's Disease. Journal of Huntington's Disease. 5: 389-394. PMID 27983561 DOI: 10.3233/JHD-160206  0.6
2015 Hyman BT, Growdon JH, Albers MW, Buckner RL, Chhatwal J, Gomez-Isla MT, Haass C, Hudry E, Jack CR, Johnson KA, Khachaturian ZS, Kim DY, Martin JB, Nitsch RM, Rosen BR, ... ... Young AB, et al. Massachusetts Alzheimer's Disease Research Center: Progress and challenges. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26297855 DOI: 10.1016/j.jalz.2015.06.1887  0.32
2013 Moscovitch-Lopatin M, Goodman RE, Eberly S, Ritch JJ, Rosas HD, Matson S, Matson W, Oakes D, Young AB, Shoulson I, Hersch SM. HTRF analysis of soluble huntingtin in PHAROS PBMCs. Neurology. 81: 1134-40. PMID 23966247 DOI: 10.1212/WNL.0b013e3182a55ede  0.96
2013 Killoran A, Biglan KM, Jankovic J, Eberly S, Kayson E, Oakes D, Young AB, Shoulson I. Characterization of the Huntington intermediate CAG repeat expansion phenotype in PHAROS. Neurology. 80: 2022-7. PMID 23624566 DOI: 10.1212/WNL.0b013e318294b304  0.96
2012 Sapp E, Valencia A, Li X, Aronin N, Kegel KB, Vonsattel JP, Young AB, Wexler N, DiFiglia M. Native mutant huntingtin in human brain: evidence for prevalence of full-length monomer. The Journal of Biological Chemistry. 287: 13487-99. PMID 22375012 DOI: 10.1074/jbc.M111.286609  0.96
2012 Ayala R, Kett LR, Leach TL, Young AB, Dunah AW, Orlando LR. Metabotropic glutamate receptor 1 (mGluR1): antibody specificity and receptor expression in cultured primary neurons. Journal of Neuroscience Methods. 204: 221-6. PMID 22155385 DOI: 10.1016/j.jneumeth.2011.11.014  0.96
2011 Shoulson I, Young AB. Milestones in huntington disease. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 1127-33. PMID 21626556 DOI: 10.1002/mds.23685  0.96
2010 Cantuti-Castelvetri I, Hernandez LF, Keller-McGandy CE, Kett LR, Landy A, Hollingsworth ZR, Saka E, Crittenden JR, Nillni EA, Young AB, Standaert DG, Graybiel AM. Levodopa-induced dyskinesia is associated with increased thyrotropin releasing hormone in the dorsal striatum of hemi-parkinsonian rats. Plos One. 5: e13861. PMID 21085660 DOI: 10.1371/journal.pone.0013861  0.96
2010 Zheng B, Liao Z, Locascio JJ, Lesniak KA, Roderick SS, Watt ML, Eklund AC, Zhang-James Y, Kim PD, Hauser MA, Grünblatt E, Moran LB, Mandel SA, Riederer P, Miller RM, ... ... Young AB, et al. PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease. Science Translational Medicine. 2: 52ra73. PMID 20926834 DOI: 10.1126/scitranslmed.3001059  0.96
2010 Zucker B, Kama JA, Kuhn A, Thu D, Orlando LR, Dunah AW, Gokce O, Taylor DM, Lambeck J, Friedrich B, Lindenberg KS, Faull RL, Weiller C, Young AB, Luthi-Carter R. Decreased Lin7b expression in layer 5 pyramidal neurons may contribute to impaired corticostriatal connectivity in huntington disease. Journal of Neuropathology and Experimental Neurology. 69: 880-95. PMID 20720508 DOI: 10.1097/NEN.0b013e3181ed7a41  0.96
2009 Young AB. Four decades of neurodegenerative disease research: how far we have come! The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12722-8. PMID 19828782 DOI: 10.1523/JNEUROSCI.3767-09.2009  0.96
2009 Orlando LR, Ayala R, Kett LR, Curley AA, Duffner J, Bragg DC, Tsai LH, Dunah AW, Young AB. Phosphorylation of the homer-binding domain of group I metabotropic glutamate receptors by cyclin-dependent kinase 5. Journal of Neurochemistry. 110: 557-69. PMID 19457112 DOI: 10.1111/j.1471-4159.2009.06139.x  0.96
2009 Crittenden JR, Cantuti-Castelvetri I, Saka E, Keller-McGandy CE, Hernandez LF, Kett LR, Young AB, Standaert DG, Graybiel AM. Dysregulation of CalDAG-GEFI and CalDAG-GEFII predicts the severity of motor side-effects induced by anti-parkinsonian therapy. Proceedings of the National Academy of Sciences of the United States of America. 106: 2892-6. PMID 19171906 DOI: 10.1073/pnas.0812822106  0.96
2009 Brocklebank D, Gayán J, Andresen JM, Roberts SA, Young AB, Snodgrass SR, Penney JB, Ramos-Arroyo MA, Cha JJ, Rosas HD, Hersch SM, Feigin A, Cherny SS, Wexler NS, Housman DE, et al. Repeat instability in the 27-39 CAG range of the HD gene in the Venezuelan kindreds: Counseling implications. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 425-9. PMID 18712713 DOI: 10.1002/ajmg.b.30826  0.96
2007 Chopra V, Fox JH, Lieberman G, Dorsey K, Matson W, Waldmeier P, Housman DE, Kazantsev A, Young AB, Hersch S. A small-molecule therapeutic lead for Huntington's disease: preclinical pharmacology and efficacy of C2-8 in the R6/2 transgenic mouse. Proceedings of the National Academy of Sciences of the United States of America. 104: 16685-9. PMID 17925440 DOI: 10.1073/pnas.0707842104  0.96
2007 Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, Volk CB, Maxwell MM, Rochet JC, McLean PJ, Young AB, Abagyan R, Feany MB, Hyman BT, Kazantsev AG. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science (New York, N.Y.). 317: 516-9. PMID 17588900 DOI: 10.1126/science.1143780  0.32
2007 Kosinski CM, Schlangen C, Gellerich FN, Gizatullina Z, Deschauer M, Schiefer J, Young AB, Landwehrmeyer GB, Toyka KV, Sellhaus B, Lindenberg KS. Myopathy as a first symptom of Huntington's disease in a Marathon runner. Movement Disorders : Official Journal of the Movement Disorder Society. 22: 1637-40. PMID 17534945 DOI: 10.1002/mds.21550  0.84
2007 Coufal M, Maxwell MM, Russel DE, Amore AM, Altmann SM, Hollingsworth ZR, Young AB, Housman DE, Kazantsev AG. Discovery of a novel small-molecule targeting selective clearance of mutant huntingtin fragments. Journal of Biomolecular Screening. 12: 351-60. PMID 17379859 DOI: 10.1177/1087057107299428  0.96
2006 Bodner RA, Outeiro TF, Altmann S, Maxwell MM, Cho SH, Hyman BT, McLean PJ, Young AB, Housman DE, Kazantsev AG. Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parkinson's diseases. Proceedings of the National Academy of Sciences of the United States of America. 103: 4246-51. PMID 16537516 DOI: 10.1073/pnas.0511256103  0.96
2006 Hodges A, Strand AD, Aragaki AK, Kuhn A, Sengstag T, Hughes G, Elliston LA, Hartog C, Goldstein DR, Thu D, Hollingsworth ZR, Collin F, Synek B, Holmans PA, Young AB, et al. Regional and cellular gene expression changes in human Huntington's disease brain. Human Molecular Genetics. 15: 965-77. PMID 16467349 DOI: 10.1093/hmg/ddl013  0.84
2005 Miller DW, Johnson JM, Solano SM, Hollingsworth ZR, Standaert DG, Young AB. Absence of alpha-synuclein mRNA expression in normal and multiple system atrophy oligodendroglia. Journal of Neural Transmission (Vienna, Austria : 1996). 112: 1613-24. PMID 16284907 DOI: 10.1007/s00702-005-0378-1  0.96
2005 Kachroo A, Orlando LR, Grandy DK, Chen JF, Young AB, Schwarzschild MA. Interactions between metabotropic glutamate 5 and adenosine A2A receptors in normal and parkinsonian mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10414-9. PMID 16280580 DOI: 10.1523/JNEUROSCI.3660-05.2005  0.96
2005 Zhang X, Smith DL, Meriin AB, Engemann S, Russel DE, Roark M, Washington SL, Maxwell MM, Marsh JL, Thompson LM, Wanker EE, Young AB, Housman DE, Bates GP, Sherman MY, et al. A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 892-7. PMID 15642944 DOI: 10.1073/pnas.0408936102  0.96
2005 Hogarth P, Kayson E, Kieburtz K, Marder K, Oakes D, Rosas D, Shoulson I, Wexler NS, Young AB, Zhao H. Interrater agreement in the assessment of motor manifestations of Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 20: 293-7. PMID 15584032 DOI: 10.1002/mds.20332  0.96
2005 Zucker B, Luthi-Carter R, Kama JA, Dunah AW, Stern EA, Fox JH, Standaert DG, Young AB, Augood SJ. Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: neuronal selectivity and potential neuroprotective role of HAP1. Human Molecular Genetics. 14: 179-89. PMID 15548548 DOI: 10.1093/hmg/ddi014  0.96
2004 Deng YP, Albin RL, Penney JB, Young AB, Anderson KD, Reiner A. Differential loss of striatal projection systems in Huntington's disease: a quantitative immunohistochemical study. Journal of Chemical Neuroanatomy. 27: 143-64. PMID 15183201 DOI: 10.1016/j.jchemneu.2004.02.005  0.96
2004 Wexler NS, Lorimer J, Porter J, Gomez F, Moskowitz C, Shackell E, Marder K, Penchaszadeh G, Roberts SA, Gayán J, Brocklebank D, Cherny SS, Cardon LR, Gray J, Dlouhy SR, ... ... Young AB, ... ... Young A, et al. Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset. Proceedings of the National Academy of Sciences of the United States of America. 101: 3498-503. PMID 14993615 DOI: 10.1073/pnas.0308679101  1
2004 Bai L, Hof PR, Standaert DG, Xing Y, Nelson SE, Young AB, Magnusson KR. Changes in the expression of the NR2B subunit during aging in macaque monkeys. Neurobiology of Aging. 25: 201-8. PMID 14749138 DOI: 10.1016/S0197-4580(03)00091-5  0.96
2003 Luthi-Carter R, Apostol BL, Dunah AW, DeJohn MM, Farrell LA, Bates GP, Young AB, Standaert DG, Thompson LM, Cha JH. Complex alteration of NMDA receptors in transgenic Huntington's disease mouse brain: analysis of mRNA and protein expression, plasma membrane association, interacting proteins, and phosphorylation. Neurobiology of Disease. 14: 624-36. PMID 14678777 DOI: 10.1016/j.nbd.2003.08.024  0.96
2003 Yohrling GJ, Jiang GC, DeJohn MM, Miller DW, Young AB, Vrana KE, Cha JH. Analysis of cellular, transgenic and human models of Huntington's disease reveals tyrosine hydroxylase alterations and substantia nigra neuropathology. Brain Research. Molecular Brain Research. 119: 28-36. PMID 14597227 DOI: 10.1016/j.molbrainres.2003.08.009  0.96
2003 Gomez-Isla T, Irizarry MC, Mariash A, Cheung B, Soto O, Schrump S, Sondel J, Kotilinek L, Day J, Schwarzschild MA, Cha JH, Newell K, Miller DW, Uéda K, Young AB, et al. Motor dysfunction and gliosis with preserved dopaminergic markers in human alpha-synuclein A30P transgenic mice. Neurobiology of Aging. 24: 245-58. PMID 12498958 DOI: 10.1016/S0197-4580(02)00091-X  0.96
2002 Orlando LR, Dunah AW, Standaert DG, Young AB. Tyrosine phosphorylation of the metabotropic glutamate receptor mGluR5 in striatal neurons. Neuropharmacology. 43: 161-73. PMID 12213270 DOI: 10.1016/S0028-3908(02)00113-2  0.96
2002 Spektor BS, Miller DW, Hollingsworth ZR, Kaneko YA, Solano SM, Johnson JM, Penney JB, Young AB, Luthi-Carter R. Differential D1 and D2 receptor-mediated effects on immediate early gene induction in a transgenic mouse model of Huntington's disease. Brain Research. Molecular Brain Research. 102: 118-28. PMID 12191502  1
2002 Chan EY, Luthi-Carter R, Strand A, Solano SM, Hanson SA, DeJohn MM, Kooperberg C, Chase KO, DiFiglia M, Young AB, Leavitt BR, Cha JH, Aronin N, Hayden MR, Olson JM. Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease. Human Molecular Genetics. 11: 1939-51. PMID 12165556  0.88
2002 Luthi-Carter R, Strand AD, Hanson SA, Kooperberg C, Schilling G, La Spada AR, Merry DE, Young AB, Ross CA, Borchelt DR, Olson JM. Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects. Human Molecular Genetics. 11: 1927-37. PMID 12165555  0.96
2002 Luthi-Carter R, Hanson SA, Strand AD, Bergstrom DA, Chun W, Peters NL, Woods AM, Chan EY, Kooperberg C, Krainc D, Young AB, Tapscott SJ, Olson JM. Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain. Human Molecular Genetics. 11: 1911-26. PMID 12165554  0.84
2002 Dunah AW, Jeong H, Griffin A, Kim YM, Standaert DG, Hersch SM, Mouradian MM, Young AB, Tanese N, Krainc D. Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease. Science (New York, N.Y.). 296: 2238-43. PMID 11988536 DOI: 10.1126/science.1072613  0.96
2001 Cha JH, Farrell LA, Ahmed SF, Frey A, Hsiao-Ashe KK, Young AB, Penney JB, Locascio JJ, Hyman BT, Irizarry MC. Glutamate receptor dysregulation in the hippocampus of transgenic mice carrying mutated human amyloid precursor protein. Neurobiology of Disease. 8: 90-102. PMID 11162243 DOI: 10.1006/nbdi.2000.0330  0.96
2001 Orlando LR, Alsdorf SA, Penney JB, Young AB. The role of group I and group II metabotropic glutamate receptors in modulation of striatal NMDA and quinolinic acid toxicity. Experimental Neurology. 167: 196-204. PMID 11161608 DOI: 10.1006/exnr.2000.7542  0.96
2000 Luthi-Carter R, Strand A, Peters NL, Solano SM, Hollingsworth ZR, Menon AS, Frey AS, Spektor BS, Penney EB, Schilling G, Ross CA, Borchelt DR, Tapscott SJ, Young AB, Cha JH, et al. Decreased expression of striatal signaling genes in a mouse model of Huntington's disease. Human Molecular Genetics. 9: 1259-71. PMID 10814708  0.96
2000 Küppenbender KD, Standaert DG, Feuerstein TJ, Penney JB, Young AB, Landwehrmeyer GB. Expression of NMDA receptor subunit mRNAs in neurochemically identified projection and interneurons in the human striatum. The Journal of Comparative Neurology. 419: 407-21. PMID 10742712 DOI: 10.1002/(SICI)1096-9861(20000417)419:4<407::AID-CNE1>3.0.CO;2-I  0.96
2000 Solano SM, Miller DW, Augood SJ, Young AB, Penney JB. Expression of alpha-synuclein, parkin, and ubiquitin carboxy-terminal hydrolase L1 mRNA in human brain: genes associated with familial Parkinson's disease. Annals of Neurology. 47: 201-10. PMID 10665491 DOI: 10.1002/1531-8249(200002)47:2<201::AID-ANA10>3.0.CO;2-F  0.96
1999 Kosinski CM, Cha JH, Young AB, Mangiarini L, Bates G, Schiefer J, Schwarz M. Intranuclear inclusions in subtypes of striatal neurons in Huntington's disease transgenic mice. Neuroreport. 10: 3891-6. PMID 10716229  0.72
1999 Kosinski CM, Cha JH, Young AB, Schwarz M. [Huntington chorea. Animal models reveal new hypotheses for pathophysiology and therapy]. Der Nervenarzt. 70: 878-88. PMID 10554779  0.72
1999 Kosinski CM, Risso Bradley S, Conn PJ, Levey AI, Landwehrmeyer GB, Penney JB, Young AB, Standaert DG. Localization of metabotropic glutamate receptor 7 mRNA and mGluR7a protein in the rat basal ganglia. The Journal of Comparative Neurology. 415: 266-84. PMID 10545164 DOI: 10.1002/(SICI)1096-9861(19991213)415:2<266::AID-CNE9>3.0.CO;2-7  0.96
1999 Cha JH, Frey AS, Alsdorf SA, Kerner JA, Kosinski CM, Mangiarini L, Penney JB, Davies SW, Bates GP, Young AB. Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 354: 981-9. PMID 10434296  0.96
1999 Ona VO, Li M, Vonsattel JP, Andrews LJ, Khan SQ, Chung WM, Frey AS, Menon AS, Li XJ, Stieg PE, Yuan J, Penney JB, Young AB, Cha JH, Friedlander RM. Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease. Nature. 399: 263-7. PMID 10353249 DOI: 10.1038/20446  0.96
1999 Standaert DG, Friberg IK, Landwehrmeyer GB, Young AB, Penney JB. Expression of NMDA glutamate receptor subunit mRNAs in neurochemically identified projection and interneurons in the striatum of the rat. Brain Research. Molecular Brain Research. 64: 11-23. PMID 9889300 DOI: 10.1016/S0169-328X(98)00293-9  0.96
1998 Daggett LP, Johnson EC, Varney MA, Lin FF, Hess SD, Deal CR, Jachec C, Lu CC, Kerner JA, Landwehrmeyer GB, Standaert DG, Young AB, Harpold MM, Veliçelebi G. The human N-methyl-D-aspartate receptor 2C subunit: genomic analysis, distribution in human brain, and functional expression. Journal of Neurochemistry. 71: 1953-68. PMID 9798920  0.96
1998 Kerner JA, Standaert DG, Penney JB, Young AB, Landwehrmeyer GB. Simultaneous isotopic and nonisotopic in situ hybridization histochemistry with cRNA probes. Brain Research. Brain Research Protocols. 3: 22-32. PMID 9767088 DOI: 10.1016/S1385-299X(98)00017-8  0.96
1998 Kosinski CM, Standaert DG, Testa CM, Penney JB, Young AB. Expression of metabotropic glutamate receptor 1 isoforms in the substantia nigra pars compacta of the rat. Neuroscience. 86: 783-98. PMID 9692717 DOI: 10.1016/S0306-4522(97)00654-4  0.96
1998 Cha JH, Kosinski CM, Kerner JA, Alsdorf SA, Mangiarini L, Davies SW, Penney JB, Bates GP, Young AB. Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene. Proceedings of the National Academy of Sciences of the United States of America. 95: 6480-5. PMID 9600992 DOI: 10.1073/pnas.95.11.6480  0.96
1998 Augood SJ, Penney JB, Friberg IK, Breakefield XO, Young AB, Ozelius LJ, Standaert DG. Expression of the early-onset torsion dystonia gene (DYT1) in human brain. Annals of Neurology. 43: 669-73. PMID 9585364 DOI: 10.1002/ana.410430518  0.96
1998 Friberg IK, Young AB, Standaert DG. Differential localization of the mRNAs for the pertussis toxin insensitive G-protein alpha sub-units Gq, G11, and Gz in the rat brain, and regulation of their expression after striatal deafferentation. Brain Research. Molecular Brain Research. 54: 298-310. PMID 9555065 DOI: 10.1016/S0169-328X(97)00346-X  0.96
1998 Counihan TJ, Landwehrmeyer GB, Standaert DG, Kosinski CM, Scherzer CR, Daggett LP, Veliçelebi G, Young AB, Penney JB. Expression of N-methyl-D-aspartate receptor subunit mRNA in the human brain: mesencephalic dopaminergic neurons. The Journal of Comparative Neurology. 390: 91-101. PMID 9456178 DOI: 10.1002/(SICI)1096-9861(19980105)390:1<91::AID-CNE8>3.0.CO;2-L  0.96
1998 Scherzer CR, Landwehrmeyer GB, Kerner JA, Counihan TJ, Kosinski CM, Standaert DG, Daggett LP, Veliçelebi G, Penney JB, Young AB. Expression of N-methyl-D-aspartate receptor subunit mRNAs in the human brain: hippocampus and cortex. The Journal of Comparative Neurology. 390: 75-90. PMID 9456177 DOI: 10.1002/(SICI)1096-9861(19980105)390:1<75::AID-CNE7>3.0.CO;2-N  0.96
1998 Kosinski CM, Standaert DG, Counihan TJ, Scherzer CR, Kerner JA, Daggett LP, Veliçelebi G, Penney JB, Young AB, Landwehrmeyer GB. Expression of N-methyl-D-aspartate receptor subunit mRNAs in the human brain: striatum and globus pallidus. The Journal of Comparative Neurology. 390: 63-74. PMID 9456176 DOI: 10.1002/(SICI)1096-9861(19980105)390:1<63::AID-CNE6>3.0.CO;2-O  0.96
1997 Testa CM, Hollingsworth ZR, Shinozaki H, Penney JB, Young AB. Selective metabotropic receptor agonists distinguish non-ionotropic glutamate binding sites. Brain Research. 773: 15-27. PMID 9409700 DOI: 10.1016/S0006-8993(97)00818-4  0.96
1997 Orlando LR, Luthi-Carter R, Standaert DG, Coyle JT, Penney JB, Young AB. N-acetylaspartylglutamate (NAAG) protects against rat striatal quinolinic acid lesions in vivo. Neuroscience Letters. 236: 91-4. PMID 9404819 DOI: 10.1016/S0304-3940(97)00769-6  0.96
1997 Sapp E, Schwarz C, Chase K, Bhide PG, Young AB, Penney J, Vonsattel JP, Aronin N, DiFiglia M. Huntingtin localization in brains of normal and Huntington's disease patients. Annals of Neurology. 42: 604-12. PMID 9382472 DOI: 10.1002/ana.410420411  0.96
1997 Wüllner U, Standaert DG, Testa CM, Penney JB, Young AB. Differential expression of kainate receptors in the basal ganglia of the developing and adult rat brain. Brain Research. 768: 215-23. PMID 9369318 DOI: 10.1016/S0006-8993(97)00645-8  0.96
1997 Kerner JA, Standaert DG, Penney JB, Young AB, Landwehrmeyer GB. Expression of group one metabotropic glutamate receptor subunit mRNAs in neurochemically identified neurons in the rat neostriatum, neocortex, and hippocampus. Brain Research. Molecular Brain Research. 48: 259-69. PMID 9332723 DOI: 10.1016/S0169-328X(97)00102-2  0.96
1997 Priller J, Scherzer CR, Faber PW, MacDonald ME, Young AB. Frataxin gene of Friedreich's ataxia is targeted to mitochondria. Annals of Neurology. 42: 265-9. PMID 9266741 DOI: 10.1002/ana.410420222  0.44
1997 Scherzer CR, Landwehrmeyer GB, Kerner JA, Standaert DG, Hollingsworth ZR, Daggett LP, Veliçelebi G, Penney JB, Young AB. Cellular distribution of NMDA glutamate receptor subunit mRNAs in the human cerebellum. Neurobiology of Disease. 4: 35-46. PMID 9258910 DOI: 10.1006/nbdi.1997.0136  0.96
1997 Lin FF, Varney M, Sacaan AI, Jachec C, Daggett LP, Rao S, Flor P, Kuhn R, Kerner JA, Standaert D, Young AB, Veliçelebi G. Cloning and stable expression of the mGluR1b subtype of human metabotropic receptors and pharmacological comparison with the mGluR5a subtype. Neuropharmacology. 36: 917-31. PMID 9257936 DOI: 10.1016/S0028-3908(97)00078-6  0.84
1997 Kosinski CM, Cha JH, Young AB, Persichetti F, MacDonald M, Gusella JF, Penney JB, Standaert DG. Huntingtin immunoreactivity in the rat neostriatum: differential accumulation in projection and interneurons. Experimental Neurology. 144: 239-47. PMID 9168825 DOI: 10.1006/exnr.1997.6441  0.96
1996 Standaert DG, Landwehrmeyer GB, Kerner JA, Penney JB, Young AB. Expression of NMDAR2D glutamate receptor subunit mRNA in neurochemically identified interneurons in the rat neostriatum, neocortex and hippocampus. Brain Research. Molecular Brain Research. 42: 89-102. PMID 8915584 DOI: 10.1016/S0169-328X(96)00117-9  0.96
1996 Rudolf GD, Cronin CA, Landwehrmeyer GB, Standaert DG, Penney JB, Young AB. Expression of N-methyl-D-aspartate glutamate receptor subunits in the prefrontal cortex of the rat. Neuroscience. 73: 417-27. PMID 8783259 DOI: 10.1016/0306-4522(96)00048-6  0.96
1996 Bhide PG, Day M, Sapp E, Schwarz C, Sheth A, Kim J, Young AB, Penney J, Golden J, Aronin N, DiFiglia M. Expression of normal and mutant huntingtin in the developing brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 5523-35. PMID 8757264  0.96
1996 Penney JB, Standaert DG, Testa CM, Landwehrmeyer GB, Young AB. Glutamate receptor genes in Parkinson's disease. Advances in Neurology. 69: 79-86. PMID 8615188  0.96
1995 Orlando LR, Standaert DG, Penney JB, Young AB. Metabotropic receptors in excitotoxicity: (S)-4-carboxy-3-hydroxyphenylglycine ((S)-4C3HPG) protects against rat striatal quinolinic acid lesions. Neuroscience Letters. 202: 109-12. PMID 8787843 DOI: 10.1016/0304-3940(95)12219-2  0.96
1995 Testa CM, Standaert DG, Landwehrmeyer GB, Penney JB, Young AB. Differential expression of mGluR5 metabotropic glutamate receptor mRNA by rat striatal neurons. The Journal of Comparative Neurology. 354: 241-52. PMID 7782501 DOI: 10.1002/cne.903540207  0.96
1995 Dure LS, Wiess S, Standaert DG, Rudolf G, Testa CM, Young AB. DNA fragmentation and immediate early gene expression in rat striatum following quinolinic acid administration. Experimental Neurology. 133: 207-14. PMID 7649226 DOI: 10.1006/exnr.1995.1023  0.96
1995 Landwehrmeyer GB, Standaert DG, Testa CM, Penney JB, Young AB. NMDA receptor subunit mRNA expression by projection neurons and interneurons in rat striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 5297-307. PMID 7623152  0.96
1995 Albin RL, Young AB, Penney JB. The functional anatomy of disorders of the basal ganglia. Trends in Neurosciences. 18: 63-4. PMID 7537410 DOI: 10.1016/0166-2236(95)80020-3  0.96
1995 Sapp E, Ge P, Aizawa H, Bird E, Penney J, Young AB, Vonsattel JP, DiFiglia M. Evidence for a preferential loss of enkephalin immunoreactivity in the external globus pallidus in low grade Huntington's disease using high resolution image analysis. Neuroscience. 64: 397-404. PMID 7535402 DOI: 10.1016/0306-4522(94)00427-7  0.96
1994 Hyman BT, Penney JB, Blackstone CD, Young AB. Localization of non-N-methyl-D-aspartate glutamate receptors in normal and Alzheimer hippocampal formation. Annals of Neurology. 35: 31-7. PMID 8285589 DOI: 10.1002/ana.410350106  0.96
1994 Catania MV, De Socarraz H, Penney JB, Young AB. Metabotropic glutamate receptor heterogeneity in rat brain. Molecular Pharmacology. 45: 626-36. PMID 8183241  0.96
1994 Testa CM, Standaert DG, Young AB, Penney JB. Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 3005-18. PMID 8182455  0.96
1994 Arregui A, Hollingsworth Z, Penney JB, Young AB. Autoradiographic evidence for increased dopamine uptake sites in striatum of hypoxic mice. Neuroscience Letters. 167: 195-7. PMID 8177524 DOI: 10.1016/0304-3940(94)91060-X  0.96
1994 Fotuhi M, Standaert DG, Testa CM, Penney JB, Young AB. Differential expression of metabotropic glutamate receptors in the hippocampus and entorhinal cortex of the rat. Brain Research. Molecular Brain Research. 21: 283-92. PMID 8170352 DOI: 10.1016/0169-328X(94)90259-3  0.96
1994 Wüllner U, Testa CM, Catania MV, Young AB, Penney JB. Glutamate receptors in striatum and substantia nigra: effects of medial forebrain bundle lesions. Brain Research. 645: 98-102. PMID 8062103 DOI: 10.1016/0006-8993(94)91642-X  0.96
1994 Standaert DG, Testa CM, Young AB, Penney JB. Organization of N-methyl-D-aspartate glutamate receptor gene expression in the basal ganglia of the rat. The Journal of Comparative Neurology. 343: 1-16. PMID 8027428 DOI: 10.1002/cne.903430102  0.96
1994 Catania MV, Landwehrmeyer GB, Testa CM, Standaert DG, Penney JB, Young AB. Metabotropic glutamate receptors are differentially regulated during development. Neuroscience. 61: 481-95. PMID 7969925 DOI: 10.1016/0306-4522(94)90428-6  0.96
1994 Wüllner U, Standaert DG, Testa CM, Landwehrmeyer GB, Catania MV, Penney JB, Young AB. Glutamate receptor expression in rat striatum: effect of deafferentation. Brain Research. 647: 209-19. PMID 7922497 DOI: 10.1016/0006-8993(94)91320-X  0.96
1994 Wüllner U, Young AB, Penney JB, Beal MF. 3-Nitropropionic acid toxicity in the striatum. Journal of Neurochemistry. 63: 1772-81. PMID 7523600  0.96
1993 Standaert DG, Testa CM, Penney JB, Young AB. Alternatively spliced isoforms of the NMDAR1 glutamate receptor subunit: differential expression in the basal ganglia of the rat. Neuroscience Letters. 152: 161-4. PMID 8515871 DOI: 10.1016/0304-3940(93)90508-I  0.96
1993 Henry TR, Frey KA, Sackellares JC, Gilman S, Koeppe RA, Brunberg JA, Ross DA, Berent S, Young AB, Kuhl DE. In vivo cerebral metabolism and central benzodiazepine-receptor binding in temporal lobe epilepsy. Neurology. 43: 1998-2006. PMID 8413957  0.96
1993 Wüllner U, Brouillet E, Isacson O, Young AB, Penney JB. Glutamate receptor binding sites in MPTP-treated mice. Experimental Neurology. 121: 284-7. PMID 8393409 DOI: 10.1006/exnr.1993.1098  0.96
1993 Price RH, Albin RL, Sakurai SY, Polinsky RJ, Penney JB, Young AB. Cerebellar excitatory and inhibitory amino acid receptors in multiple system atrophy. Neurology. 43: 1323-8. PMID 8392149  0.84
1993 Holthoff VA, Koeppe RA, Frey KA, Penney JB, Markel DS, Kuhl DE, Young AB. Positron emission tomography measures of benzodiazepine receptors in Huntington's disease. Annals of Neurology. 34: 76-81. PMID 8390806 DOI: 10.1002/ana.410340114  0.84
1993 Price RH, Hollingsworth Z, Young AB, Penney JB. Excitatory amino acid receptor regulation after subthalamic nucleus lesions in the rat. Brain Research. 602: 157-60. PMID 8383570 DOI: 10.1016/0006-8993(93)90257-N  0.84
1993 Sakurai SY, Penney JB, Young AB. Regionally distinct N-methyl-D-aspartate receptors distinguished by quantitative autoradiography of [3H]MK-801 binding in rat brain. Journal of Neurochemistry. 60: 1344-53. PMID 8095974  0.96
1993 Carlson MD, Penney JB, Young AB. NMDA, AMPA, and benzodiazepine binding site changes in Alzheimer's disease visual cortex. Neurobiology of Aging. 14: 343-52. PMID 7690114 DOI: 10.1016/0197-4580(93)90120-Z  0.84
1993 Catania MV, Hollingsworth Z, Penney JB, Young AB. Quisqualate resolves two distinct metabotropic [3H]glutamate binding sites. Neuroreport. 4: 311-3. PMID 7682857  0.84
1993 Catania MV, Hollingsworth Z, Penney JB, Young AB. Phospholipase A2 modulates different subtypes of excitatory amino acid receptors: autoradiographic evidence. Journal of Neurochemistry. 60: 236-45. PMID 7678040  0.92
1992 Kincaid AE, Albin RL, Newman SW, Penney JB, Young AB. 6-Hydroxydopamine lesions of the nigrostriatal pathway alter the expression of glutamate decarboxylase messenger RNA in rat globus pallidus projection neurons. Neuroscience. 51: 705-18. PMID 1488118 DOI: 10.1016/0306-4522(92)90309-P  0.96
1992 Dure LS, Young AB, Penney JB. Compartmentalization of excitatory amino acid receptors in human striatum. Proceedings of the National Academy of Sciences of the United States of America. 89: 7688-92. PMID 1380163  0.92
1992 Cha JH, Makowiec RL, Penney JB, Young AB. Multiple states of rat brain (RS)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors as revealed by quantitative autoradiography. Molecular Pharmacology. 41: 832-8. PMID 1375315  0.92
1992 Albin RL, Reiner A, Anderson KD, Dure LS, Handelin B, Balfour R, Whetsell WO, Penney JB, Young AB. Preferential loss of striato-external pallidal projection neurons in presymptomatic Huntington's disease. Annals of Neurology. 31: 425-30. PMID 1375014 DOI: 10.1002/ana.410310412  0.96
1992 Difazio MC, Hollingsworth Z, Young AB, Penney JB. Glutamate receptors in the substantia nigra of Parkinson's disease brains. Neurology. 42: 402-6. PMID 1346548  0.84
1992 Tallaksen-Greene SJ, Young AB, Penney JB, Beitz AJ. Excitatory amino acid binding sites in the trigeminal principal sensory and spinal trigeminal nuclei of the rat. Neuroscience Letters. 141: 79-83. PMID 1324445 DOI: 10.1016/0304-3940(92)90339-9  0.96
1992 Olson JM, McNeel W, Young AB, Mancini WR. Localization of the peripheral-type benzodiazepine binding site to mitochondria of human glioma cells. Journal of Neuro-Oncology. 13: 35-42. PMID 1319474  0.36
1992 Albin RL, Makowiec RL, Hollingsworth ZR, Dure LS, Penney JB, Young AB. Excitatory amino acid binding sites in the basal ganglia of the rat: a quantitative autoradiographic study. Neuroscience. 46: 35-48. PMID 1317515 DOI: 10.1016/0306-4522(92)90006-N  0.92
1991 Albin RL, Makowiec RL, Hollingsworth Z, Sakurai SY, Dure LS, Penney JB, Young AB. Excitatory amino acidergic pathways and receptors in the basal ganglia. Amino Acids. 1: 339-50. PMID 24194174 DOI: 10.1007/BF00814003  0.96
1991 Sakurai SY, Cha JH, Penney JB, Young AB. Regional distribution and properties of [3H]MK-801 binding sites determined by quantitative autoradiography in rat brain. Neuroscience. 40: 533-43. PMID 2027471 DOI: 10.1016/0306-4522(91)90139-F  0.84
1991 Kincaid AE, Penney JB, Young AB, Newman SW. The globus pallidus receives a projection from the parafascicular nucleus in the rat. Brain Research. 553: 18-26. PMID 1933274 DOI: 10.1016/0006-8993(91)90224-J  0.96
1991 Maragos WF, Greenamyre JT, Chu DC, Penney JB, Young AB. A study of cortical and hippocampal NMDA and PCP receptors following selective cortical and subcortical lesions. Brain Research. 538: 36-45. PMID 1850317 DOI: 10.1016/0006-8993(91)90373-4  0.92
1991 Albin RL, Qin Y, Young AB, Penney JB, Chesselet MF. Preproenkephalin messenger RNA-containing neurons in striatum of patients with symptomatic and presymptomatic Huntington's disease: an in situ hybridization study. Annals of Neurology. 30: 542-9. PMID 1838677 DOI: 10.1002/ana.410300406  0.96
1991 Albin RL, Price RH, Sakurai SY, Penney JB, Young AB. Excitatory and inhibitory amino acid binding sites in human dentate nucleus. Brain Research. 560: 350-3. PMID 1760743 DOI: 10.1016/0006-8993(91)91258-3  0.92
1991 Makowiec RL, Cha JJ, Penney JB, Young AB. Cerebellar excitatory amino acid binding sites in normal, granuloprival, and Purkinje cell-deficient mice. Neuroscience. 42: 671-81. PMID 1683473 DOI: 10.1016/0306-4522(91)90036-N  0.96
1991 Albin RL, Sakurai SY, Makowiec RL, Higgins DS, Young AB, Penney JB. Excitatory amino acid, GABA(A), and GABA(B) binding sites in human striate cortex. Cerebral Cortex (New York, N.Y. : 1991). 1: 499-509. PMID 1668367 DOI: 10.1093/cercor/1.6.499  0.96
1991 Dure LS, Young AB, Penney JB. Excitatory amino acid binding sites in the caudate nucleus and frontal cortex of Huntington's disease. Annals of Neurology. 30: 785-93. PMID 1665055 DOI: 10.1002/ana.410300607  0.96
1991 Cha JH, Dure LS IV, Sakurai SY, Penney JB, Young AB. 2,4,5-Trihydroxyphenylalanine (6-hydroxy-dopa) displaces [3H]AMPA binding in rat striatum. Neuroscience Letters. 132: 55-8. PMID 1664920 DOI: 10.1016/0304-3940(91)90432-S  0.96
1991 Kincaid AE, Penney JB, Young AB, Newman SW. Evidence for a projection from the globus pallidus to the entopeduncular nucleus in the rat. Neuroscience Letters. 128: 121-5. PMID 1656332 DOI: 10.1016/0304-3940(91)90774-N  0.96
1990 Albin RL, Makowiec RL, Hollingsworth Z, Dure LS, Penney JB, Young AB. Excitatory amino acid binding sites in the periaqueductal gray of the rat. Neuroscience Letters. 118: 112-5. PMID 2175406 DOI: 10.1016/0304-3940(90)90261-7  0.84
1990 Greenamyre JT, Higgins DS, Young AB, Penney JB. Regional ontogeny of a unique glutamate recognition site in rat brain: an autoradiographic study. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 8: 437-45. PMID 2174635 DOI: 10.1016/0736-5748(90)90076-E  0.96
1990 McDonald JW, Johnston MV, Young AB. Differential ontogenic development of three receptors comprising the NMDA receptor/channel complex in the rat hippocampus. Experimental Neurology. 110: 237-47. PMID 2174375  0.8
1990 McDonald JW, Penney JB, Johnston MV, Young AB. Characterization and regional distribution of strychnine-insensitive [3H]glycine binding sites in rat brain by quantitative receptor autoradiography. Neuroscience. 35: 653-68. PMID 2166246 DOI: 10.1016/0306-4522(90)90336-3  0.92
1990 Penney JB, Maragos WF, Greenamyre JT, Debowey DL, Hollingsworth Z, Young AB. Excitatory amino acid binding sites in the hippocampal region of Alzheimer's disease and other dementias. Journal of Neurology, Neurosurgery, and Psychiatry. 53: 314-20. PMID 2160518  0.96
1990 Greenamyre JT, Higgins DS, Young AB. Sodium-dependent D-aspartate 'binding' is not a measure of presynaptic neuronal uptake sites in an autoradiographic assay. Brain Research. 511: 310-8. PMID 2159361 DOI: 10.1016/0006-8993(90)90176-C  1
1990 Chu DC, Albin RL, Young AB, Penney JB. Distribution and kinetics of GABAB binding sites in rat central nervous system: a quantitative autoradiographic study. Neuroscience. 34: 341-57. PMID 2159128 DOI: 10.1016/0306-4522(90)90144-S  1
1990 Penney JB, Young AB, Shoulson I, Starosta-Rubenstein S, Snodgrass SR, Sanchez-Ramos J, Ramos-Arroyo M, Gomez F, Penchaszadeh G, Alvir J. Huntington's disease in Venezuela: 7 years of follow-up on symptomatic and asymptomatic individuals. Movement Disorders : Official Journal of the Movement Disorder Society. 5: 93-9. PMID 2139171 DOI: 10.1002/mds.870050202  0.96
1990 Young AB, Dauth GW, Hollingsworth Z, Penney JB, Kaatz K, Gilman S. Quisqualate- and NMDA-sensitive [3H]glutamate binding in primate brain. Journal of Neuroscience Research. 27: 512-21. PMID 1981916 DOI: 10.1002/jnr.490270412  0.84
1990 Makowiec RL, Albin RL, Cha JH, Young AB, Gilman S. Two types of quisqualate receptors are decreased in human olivopontocerebellar atrophy cerebellar cortex. Brain Research. 523: 309-12. PMID 1976026  0.92
1990 Cha JH, Makowiec RL, Penney JB, Young AB. L-[3H]glutamate labels the metabotropic excitatory amino acid receptor in rodent brain. Neuroscience Letters. 113: 78-83. PMID 1973276 DOI: 10.1016/0304-3940(90)90498-X  0.92
1990 Albin RL, Reiner A, Anderson KD, Penney JB, Young AB. Striatal and nigral neuron subpopulations in rigid Huntington's disease: implications for the functional anatomy of chorea and rigidity-akinesia. Annals of Neurology. 27: 357-65. PMID 1972318 DOI: 10.1002/ana.410270403  0.52
1990 Nielsen EO, Drejer J, Cha JH, Young AB, Honoré T. Autoradiographic characterization and localization of quisqualate binding sites in rat brain using the antagonist [3H]6-cyano-7-nitroquinoxaline-2,3-dione: comparison with (R,S)-[3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding sites. Journal of Neurochemistry. 54: 686-95. PMID 1967632  0.52
1990 Albin RL, Young AB, Penney JB, Handelin B, Balfour R, Anderson KD, Markel DS, Tourtellotte WW, Reiner A. Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease. The New England Journal of Medicine. 322: 1293-8. PMID 1691447 DOI: 10.1056/NEJM199005033221807  0.84
1989 Conneally PM, Haines JL, Tanzi RE, Wexler NS, Penchaszadeh GK, Harper PS, Folstein SE, Cassiman JJ, Myers RH, Young AB. Huntington disease: no evidence for locus heterogeneity. Genomics. 5: 304-8. PMID 2571579 DOI: 10.1016/0888-7543(89)90062-1  0.44
1989 Albin RL, Aldridge JW, Young AB, Gilman S. Feline subthalamic nucleus neurons contain glutamate-like but not GABA-like or glycine-like immunoreactivity. Brain Research. 491: 185-8. PMID 2569908  0.92
1989 Cha JH, Hollingsworth ZR, Greenamyre JT, Young AB. Contamination of commercially available quisqualic acid by glutamate-like and aspartate-like substances. Journal of Neuroscience Methods. 27: 143-8. PMID 2565415 DOI: 10.1016/0165-0270(89)90097-6  0.96
1989 Greenamyre JT, Young AB. Excitatory amino acids and Alzheimer's disease. Neurobiology of Aging. 10: 593-602. PMID 2554168 DOI: 10.1016/0197-4580(89)90143-7  0.96
1989 Gildersleeve DL, Lin TY, Wieland DM, Ciliax BJ, Olson JM, Young AB. Synthesis of a high specific activity 125I-labeled analog of PK 11195, potential agent for SPECT imaging of the peripheral benzodiazepine binding site. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 16: 423-9. PMID 2550392  0.6
1989 Greenamyre JT, Young AB. Synaptic localization of striatal NMDA, quisqualate and kainate receptors. Neuroscience Letters. 101: 133-7. PMID 2549458 DOI: 10.1016/0304-3940(89)90519-3  0.96
1989 Yang DJ, Ciliax BJ, Van Dort ME, Gildersleeve D, Pirat JL, Young AB, Wieland DM. Synthesis and receptor binding studies of (+/-)1-iodo-MK-801. Pharmaceutical Research. 6: 474-6. PMID 2548173  0.6
1989 McDonald JW, Cline HT, Constantine-Paton M, Maragos WF, Johnston MV, Young AB. Quantitative autoradiographic localization of NMDA, quisqualate and PCP receptors in the frog tectum. Brain Research. 482: 155-8. PMID 2539881 DOI: 10.1016/0006-8993(89)90553-2  0.96
1989 Irwin CC, Wexler NS, Young AB, Ozelius LJ, Penney JB, Shoulson I, Snodgrass SR, Ramos-Arroyo MA, Sanchez-Ramos J, Penchaszadeh GK. The role of mitochondrial DNA in Huntington's disease. Journal of Molecular Neuroscience : Mn. 1: 129-36. PMID 2534902 DOI: 10.1007/BF02918898  0.96
1989 Richfield EK, Penney JB, Young AB. Anatomical and affinity state comparisons between dopamine D1 and D2 receptors in the rat central nervous system. Neuroscience. 30: 767-77. PMID 2528080 DOI: 10.1016/0306-4522(89)90168-1  1
1989 Richfield EK, Young AB, Penney JB. Comparative distributions of dopamine D-1 and D-2 receptors in the cerebral cortex of rats, cats, and monkeys. The Journal of Comparative Neurology. 286: 409-26. PMID 2506254 DOI: 10.1002/cne.902860402  0.92
1989 Albin RL, Young AB, Penney JB. The functional anatomy of basal ganglia disorders. Trends in Neurosciences. 12: 366-75. PMID 2479133 DOI: 10.1016/0166-2236(89)90074-X  0.92
1988 Olson JM, Junck L, Young AB, Penney JB, Mancini WR. Isoquinoline and peripheral-type benzodiazepine binding in gliomas: implications for diagnostic imaging. Cancer Research. 48: 5837-41. PMID 3262414  0.56
1988 Gilman S, Junck L, Young AB, Hichwa RD, Markel DS, Koeppe RA, Ehrenkaufer RL. Cerebral metabolic activity in idiopathic dystonia studied with positron emission tomography. Advances in Neurology. 50: 231-6. PMID 3261114  0.68
1988 Albin RL, Young AB. Somatosensory phenomena in Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 3: 343-6. PMID 2974928 DOI: 10.1002/mds.870030411  0.92
1988 Berent S, Giordani B, Lehtinen S, Markel D, Penney JB, Buchtel HA, Starosta-Rubinstein S, Hichwa R, Young AB. Positron emission tomographic scan investigations of Huntington's disease: cerebral metabolic correlates of cognitive function. Annals of Neurology. 23: 541-6. PMID 2970247 DOI: 10.1002/ana.410230603  0.96
1988 Nielsen EO, Cha JH, Honoré T, Penney JB, Young AB. Thiocyanate stabilizes AMPA binding to the quisqualate receptor. European Journal of Pharmacology. 157: 197-203. PMID 2906292 DOI: 10.1016/0014-2999(88)90383-4  0.92
1988 Greenamyre JT, Maragos WF, Albin RL, Penney JB, Young AB. Glutamate transmission and toxicity in Alzheimer's disease. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 12: 421-30. PMID 2900537 DOI: 10.1016/0278-5846(88)90102-9  0.96
1988 Cha JH, Greenamyre JT, Nielsen EO, Penney JB, Young AB. Properties of quisqualate-sensitive L-[3H]glutamate binding sites in rat brain as determined by quantitative autoradiography. Journal of Neurochemistry. 51: 469-78. PMID 2899133  0.96
1988 Wieland DM, Kilbourn MR, Yang DJ, Laborde E, Gildersleeve DL, Van Dort ME, Pirat JL, Ciliax BJ, Young AB. NMDA receptor channels: labeling of MK-801 with iodine-125 and fluorine-18. International Journal of Radiation Applications and Instrumentation. Part a, Applied Radiation and Isotopes. 39: 1219-25. PMID 2851002 DOI: 10.1016/0883-2889(88)90103-7  0.56
1988 Olson JM, Ciliax BJ, Mancini WR, Young AB. Presence of peripheral-type benzodiazepine binding sites on human erythrocyte membranes. European Journal of Pharmacology. 152: 47-53. PMID 2850202  0.6
1988 Van Dort ME, Ciliax BJ, Gildersleeve DL, Sherman PS, Rosenspire KC, Young AB, Junck L, Wieland DM. Radioiodinated benzodiazepines: agents for mapping glial tumors. Journal of Medicinal Chemistry. 31: 2081-6. PMID 2846836  0.6
1988 Young AB, Greenamyre JT, Hollingsworth Z, Albin R, D'Amato C, Shoulson I, Penney JB. NMDA receptor losses in putamen from patients with Huntington's disease. Science (New York, N.Y.). 241: 981-3. PMID 2841762  0.96
1988 Richfield EK, Ciliax BJ, Starosta-Rubinstein SR, McKeever PE, Penney JB, Young AB. Comparison of [14C]-deoxyglucose metabolism and peripheral benzodiazepine receptor binding in rat C6 glioma. Neurology. 38: 1255-62. PMID 2840604  0.56
1988 Albin RL, Young AB, Penney JB. Tetrahydro-9-aminoacridine (THA) interacts with the phencyclidine (PCP) receptor site. Neuroscience Letters. 88: 303-7. PMID 2838771 DOI: 10.1016/0304-3940(88)90228-5  1
1988 Maragos WF, Penney JB, Young AB. Anatomic correlation of NMDA and 3H-TCP-labeled receptors in rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 493-501. PMID 2828564  0.96
1988 Reiner A, Albin RL, Anderson KD, D'Amato CJ, Penney JB, Young AB. Differential loss of striatal projection neurons in Huntington disease. Proceedings of the National Academy of Sciences of the United States of America. 85: 5733-7. PMID 2456581  0.32
1987 Starosta-Rubinstein S, Young AB, Kluin K, Hill G, Aisen AM, Gabrielsen T, Brewer GJ. Clinical assessment of 31 patients with Wilson's disease. Correlations with structural changes on magnetic resonance imaging. Archives of Neurology. 44: 365-70. PMID 3827691  0.4
1987 Maragos WF, Chu DC, Young AB, D'Amato CJ, Penney JB. Loss of hippocampal [3H]TCP binding in Alzheimer's disease. Neuroscience Letters. 74: 371-6. PMID 3031556 DOI: 10.1016/0304-3940(87)90326-0  0.92
1987 Starosta-Rubinstein S, Ciliax BJ, Penney JB, McKeever P, Young AB. Imaging of a glioma using peripheral benzodiazepine receptor ligands. Proceedings of the National Academy of Sciences of the United States of America. 84: 891-5. PMID 3027710 DOI: 10.1073/pnas.84.3.891  0.32
1987 Richfield EK, Young AB, Penney JB. Comparative distribution of dopamine D-1 and D-2 receptors in the basal ganglia of turtles, pigeons, rats, cats, and monkeys. The Journal of Comparative Neurology. 262: 446-63. PMID 2958517 DOI: 10.1002/cne.902620308  1
1987 Richfield EK, Debowey DL, Penney JB, Young AB. Basal ganglia and cerebral cortical distribution of dopamine D1- and D2-receptors in neonatal and adult cat brain. Neuroscience Letters. 73: 203-8. PMID 2951618 DOI: 10.1016/0304-3940(87)90245-X  0.8
1987 Young AB, Penney JB, Starosta-Rubinstein S, Markel D, Berent S, Rothley J, Betley A, Hichwa R. Normal caudate glucose metabolism in persons at risk for Huntington's disease. Archives of Neurology. 44: 254-7. PMID 2950844 DOI: 10.1001/archneur.1987.00520150010010  0.96
1987 Markel DS, Young AB, Penney JB. At-risk persons' attitudes toward presymptomatic and prenatal testing of Huntington disease in Michigan. American Journal of Medical Genetics. 26: 295-305. PMID 2949613 DOI: 10.1002/ajmg.1320260207  0.92
1987 Bromberg MB, Pamel G, Stephenson BS, Young AB, Penney JB. Evidence for reactive synaptogenesis in the ventrolateral thalamus and red nucleus of the rat: changes in high affinity glutamate uptake and numbers of corticofugal fiber terminals. Experimental Brain Research. 69: 53-9. PMID 2893742 DOI: 10.1007/BF00247028  0.72
1987 Olson JM, Greenamyre JT, Penney JB, Young AB. Autoradiographic localization of cerebellar excitatory amino acid binding sites in the mouse. Neuroscience. 22: 913-23. PMID 2891079 DOI: 10.1016/0306-4522(87)92969-1  0.96
1987 Greenamyre T, Penney JB, Young AB, Hudson C, Silverstein FS, Johnston MV. Evidence for transient perinatal glutamatergic innervation of globus pallidus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 1022-30. PMID 2883265  0.8
1987 Wexler NS, Young AB, Tanzi RE, Travers H, Starosta-Rubinstein S, Penney JB, Snodgrass SR, Shoulson I, Gomez F, Ramos Arroyo MA. Homozygotes for Huntington's disease. Nature. 326: 194-7. PMID 2881213 DOI: 10.1038/326194a0  0.96
1987 Greenamyre JT, Penney JB, D'Amato CJ, Young AB. Dementia of the Alzheimer's type: changes in hippocampal L-[3H]glutamate binding. Journal of Neurochemistry. 48: 543-51. PMID 2878980  0.96
1987 Chu DC, Penney JB, Young AB. Quantitative autoradiography of hippocampal GABAB and GABAA receptor changes in Alzheimer's disease. Neuroscience Letters. 82: 246-52. PMID 2827074 DOI: 10.1016/0304-3940(87)90264-3  0.92
1987 Chu DC, Penney JB, Young AB. Cortical GABAB and GABAA receptors in Alzheimer's disease: a quantitative autoradiographic study. Neurology. 37: 1454-9. PMID 2819782  1
1986 Richfield EK, Young AB, Penney JB. Properties of D2 dopamine receptor autoradiography: high percentage of high-affinity agonist sites and increased nucleotide sensitivity in tissue sections. Brain Research. 383: 121-8. PMID 3768686 DOI: 10.1016/0006-8993(86)90013-2  1
1986 Frey KA, Agranoff BW, Young AB, Hichwa RD, Ehrenkaufer RL. Human brain receptor distribution. Science (New York, N.Y.). 232: 1269-71. PMID 3704652  0.52
1986 Ciliax BJ, Penney JB, Young AB. In vivo [3H]flunitrazepam binding: imaging of receptor regulation. The Journal of Pharmacology and Experimental Therapeutics. 238: 749-57. PMID 3016249  0.8
1986 Maragos WF, Chu DC, Greenamyre JT, Penney JB, Young AB. High correlation between the localization of [3H]TCP binding and NMDA receptors. European Journal of Pharmacology. 123: 173-4. PMID 3011454 DOI: 10.1016/0014-2999(86)90703-X  0.96
1986 Young AB, Penney JB, Starosta-Rubinstein S, Markel DS, Berent S, Giordani B, Ehrenkaufer R, Jewett D, Hichwa R. PET scan investigations of Huntington's disease: cerebral metabolic correlates of neurological features and functional decline. Annals of Neurology. 20: 296-303. PMID 2945510 DOI: 10.1002/ana.410200305  0.96
1986 Young AB, Shoulson I, Penney JB, Starosta-Rubinstein S, Gomez F, Travers H, Ramos-Arroyo MA, Snodgrass SR, Bonilla E, Moreno H. Huntington's disease in Venezuela: neurologic features and functional decline. Neurology. 36: 244-9. PMID 2935747  0.96
1986 Penney JB, Young AB. Striatal inhomogeneities and basal ganglia function. Movement Disorders : Official Journal of the Movement Disorder Society. 1: 3-15. PMID 2848190 DOI: 10.1002/mds.870010102  0.92
1985 Johnston MV, Silverstein FS, Reindel FO, Penney JB, Young AB. Muscarinic cholinergic receptors in human infant forebrain: [3H]quinuclidinyl benzilate binding in homogenates and quantitative autoradiography in sections. Brain Research. 351: 195-203. PMID 3995346 DOI: 10.1016/0165-3806(85)90191-9  0.8
1985 Pan HS, Penney JB, Young AB. Gamma-aminobutyric acid and benzodiazepine receptor changes induced by unilateral 6-hydroxydopamine lesions of the medial forebrain bundle. Journal of Neurochemistry. 45: 1396-404. PMID 2995585  0.92
1985 Greenamyre JT, Olson JM, Penney JB, Young AB. Autoradiographic characterization of N-methyl-D-aspartate-, quisqualate- and kainate-sensitive glutamate binding sites. The Journal of Pharmacology and Experimental Therapeutics. 233: 254-63. PMID 2984415  0.96
1985 Greenamyre JT, Penney JB, Young AB, D'Amato CJ, Hicks SP, Shoulson I. Alterations in L-glutamate binding in Alzheimer's and Huntington's diseases. Science (New York, N.Y.). 227: 1496-9. PMID 2858129  0.96
1984 Pan HS, Dauth GW, Young AB, Penney JB. Computer-assisted estimates of lesion sizes and shrinkage in denervated areas from receptor autoradiograms using a digitizing tablet. Neuroscience Letters. 44: 277-80. PMID 6728297 DOI: 10.1016/0304-3940(84)90035-1  0.84
1984 Young AB, Penney JB. Neurochemical anatomy of movement disorders. Neurologic Clinics. 2: 417-33. PMID 6152481  1
1984 Pan HS, Penney JB, Young AB. Characterization of benzodiazepine receptor changes in substantia nigra, globus pallidus and entopeduncular nucleus after striatal lesions. The Journal of Pharmacology and Experimental Therapeutics. 230: 768-75. PMID 6147405  0.8
1984 Abou-Khalil B, Young AB, Penney JB. Evidence for the presynaptic localization of opiate binding sites on striatal efferent fibers. Brain Research. 323: 21-9. PMID 6098334 DOI: 10.1016/0006-8993(84)90261-0  0.92
1984 Young AB, Pan HS, Ciliax BJ, Penney JB. GABA and benzodiazepine receptors in basal ganglia function. Neuroscience Letters. 47: 361-7. PMID 6089057 DOI: 10.1016/0304-3940(84)90540-8  0.84
1984 Greenamyre JT, Young AB, Penney JB. Quantitative autoradiographic distribution of L-[3H]glutamate-binding sites in rat central nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 4: 2133-44. PMID 6088729  0.96
1984 Walker FO, Young AB, Penney JB, Dovorini-Zis K, Shoulson I. Benzodiazepine and GABA receptors in early Huntington's disease. Neurology. 34: 1237-40. PMID 6087209  0.84
1983 Penney JB, Young AB. Speculations on the functional anatomy of basal ganglia disorders. Annual Review of Neuroscience. 6: 73-94. PMID 6838141 DOI: 10.1146/annurev.ne.06.030183.000445  1
1983 Pan HS, Frey KA, Young AB, Penney JB. Changes in [3H]muscimol binding in substantia nigra, entopeduncular nucleus, globus pallidus, and thalamus after striatal lesions as demonstrated by quantitative receptor autoradiography. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 1189-98. PMID 6304260  0.92
1983 Young AB, Penney JB, Dauth GW, Bromberg MB, Gilman S. Glutamate or aspartate as a possible neurotransmitter of cerebral corticofugal fibers in the monkey. Neurology. 33: 1513-6. PMID 6138734  0.92
1983 Greenamyre JT, Young AB, Penney JB. Quantitative autoradiography of L-[3H]glutamate binding to rat brain. Neuroscience Letters. 37: 155-60. PMID 6136011 DOI: 10.1016/0304-3940(83)90146-5  0.96
1982 Penney JB, Young AB. Quantitative autoradiography of neurotransmitter receptors in Huntington disease. Neurology. 32: 1391-5. PMID 6292789  0.84
1982 Nowak LM, Young AB, Macdonald RL. GABA and bicuculline actions on mouse spinal cord and cortical neurons in cell culture. Brain Research. 244: 155-64. PMID 6288177 DOI: 10.1016/0006-8993(82)90913-1  0.96
1981 Penney JB, Pan HS, Young AB, Frey KA, Dauth GW. Quantitative autoradiography of [3H]muscimol binding in rat brain. Science (New York, N.Y.). 214: 1036-8. PMID 6272394  1
1981 Penney JB, Frey K, Young AB. Quantitative autoradiography of neurotransmitter receptors using tritium-sensitive film. European Journal of Pharmacology. 72: 421-2. PMID 6268430 DOI: 10.1016/0014-2999(81)90591-4  0.48
1981 Bromberg MB, Penney JB, Stephenson BS, Young AB. Evidence for glutamate as the neurotransmitter of corticothalamic and corticorubral pathways. Brain Research. 215: 369-74. PMID 6167322 DOI: 10.1016/0006-8993(81)90519-9  0.8
1977 Snyder SH, Enna SJ, Young AB. Brain mechanisms associated with therapeutic actions of benzodiazepines: focus on neurotransmitters. The American Journal of Psychiatry. 134: 662-5. PMID 17304  1
1975 Zukin SR, Young AB, Snyder SH. Development of the synaptic glycine receptor in chick embryo spinal cord. Brain Research. 83: 525-30. PMID 163119 DOI: 10.1016/0006-8993(75)90848-3  0.52
1974 Young AB, Snyder SH. The glycine synaptic receptor: evidence that strychnine binding is associated with the ionic conductance mechanism. Proceedings of the National Academy of Sciences of the United States of America. 71: 4002-5. PMID 4372600  1
1974 Zukin SR, Young AB, Snyder SH. Gamma-aminobutyric acid binding to receptor sites in the rat central nervous system. Proceedings of the National Academy of Sciences of the United States of America. 71: 4802-7. PMID 4155072  0.52
1974 Young AB, Zukin SR, Snyder SH. Interaction of benzodiazepines with central nervous glycine receptors: possible mechanism of action. Proceedings of the National Academy of Sciences of the United States of America. 71: 2246-50. PMID 4152296  0.52
1974 Young AB, Oster-Granite ML, Herndon RM, Snyder SH. Glutamic acid: selective depletion by viral induced granule cell loss in hamster cerebellum. Brain Research. 73: 1-13. PMID 4152168 DOI: 10.1016/0006-8993(74)91002-6  0.52
1973 Young AB, Snyder SH. A sensitive specific enzymatic-fluorometric assay for homocarnosine. Journal of Neurochemistry. 21: 387-96. PMID 4724325  1
1973 Snyder SH, Young AB, Bennett JP, Mulder AH. Synaptic biochemistry of amino acids. Federation Proceedings. 32: 2039-47. PMID 4355732  1
1973 Young AB, Snyder SH. Strychnine binding associated with glycine receptors of the central nervous system. Proceedings of the National Academy of Sciences of the United States of America. 70: 2832-6. PMID 4200724  1
1971 Young AB, Pert CD, Brown DG, Taylor KM, Snyder SH. Nuclear localization of histamine in neonatal rat brain. Science (New York, N.Y.). 173: 247-9. PMID 5104178  0.52
Show low-probability matches.