Priya Luthra, Ph.D. - Publications

Affiliations: 
2011 Pennsylvania State University, State College, PA, United States 
Area:
Virology Biology, Microbiology Biology, Cell Biology

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Williams CG, Gibbons JS, Keiffer TR, Luthra P, Edwards MR, Basler CF. Impact of Měnglà virus proteins on human and bat innate immune pathways. Journal of Virology. PMID 32295912 DOI: 10.1128/Jvi.00191-20  0.457
2019 Woolsey C, Menicucci AR, Cross RW, Luthra P, Agans KN, Borisevich V, Geisbert JB, Mire CE, Fenton KA, Jankeel A, Anand S, Ebihara H, Geisbert TW, Messaoudi I, Basler CF. A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge. Cell Reports. 28: 3032-3046.e6. PMID 31533029 DOI: 10.1016/J.Celrep.2019.08.047  0.34
2019 Lim HK, Huang SXL, Chen J, Kerner G, Gilliaux O, Bastard P, Dobbs K, Hernandez N, Goudin N, Hasek ML, García Reino EJ, Lafaille FG, Lorenzo L, Luthra P, Kochetkov T, et al. Severe influenza pneumonitis in children with inherited TLR3 deficiency. The Journal of Experimental Medicine. PMID 31217193 DOI: 10.1084/Jem.20181621  0.308
2019 Amatya P, Wagner N, Chen G, Luthra P, Shi L, Borek D, Pavlenco A, Rohrs HW, Basler CF, Sidhu SS, Gross ML, Leung DW. Marburg virus RNA synthesis is inhibited by a synthetic anti-VP35 antibody. Acs Infectious Diseases. PMID 31120240 DOI: 10.1021/ACSINFECDIS.9B00091  0.366
2018 Batra J, Hultquist JF, Liu D, Shtanko O, Von Dollen J, Satkamp L, Jang GM, Luthra P, Schwarz TM, Small GI, Arnett E, Anantpadma M, Reyes A, Leung DW, Kaake R, et al. Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication. Cell. 175: 1917-1930.e13. PMID 30550789 DOI: 10.1016/J.Cell.2018.08.044  0.37
2018 Luthra P, Naidoo J, Pietzsch CA, De S, Khadka S, Anantpadma M, Williams CG, Edwards MR, Davey RA, Bukreyev A, Ready JM, Basler CF. Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses. Antiviral Research. PMID 30144461 DOI: 10.1016/J.Antiviral.2018.08.012  0.377
2018 Edwards MR, Liu H, Shabman RS, Ginell GM, Luthra P, Ramanan P, Keefe LJ, Köllner B, Amarasinghe GK, Taylor DJ, Leung DW, Basler CF. Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes. Cell Reports. 24: 861-872.e6. PMID 30044983 DOI: 10.1016/J.Celrep.2018.06.045  0.37
2018 Fink SL, Vojtech L, Wagoner J, Slivinski NSJ, Jackson KJ, Wang R, Khadka S, Luthra P, Basler CF, Polyak SJ. The Antiviral Drug Arbidol Inhibits Zika Virus. Scientific Reports. 8: 8989. PMID 29895962 DOI: 10.1038/S41598-018-27224-4  0.362
2017 Luthra P, Liang J, Pietzsch CA, Khadka S, Edwards MR, Wei S, De S, Posner B, Bukreyev A, Ready JM, Basler CF. A high throughput screen identifies benzoquinoline compounds as inhibitors of Ebola virus replication. Antiviral Research. PMID 29294299 DOI: 10.1016/J.Antiviral.2017.12.019  0.37
2017 Bharaj P, Atkins C, Luthra P, Giraldo MI, Dawes BE, Miorin L, Johnson JR, Krogan NJ, Basler CF, Freiberg AN, Rajsbaum R. The host E3-Ubiquitin ligase TRIM6 ubiquitinates the Ebola virus VP35 protein and promotes virus replication. Journal of Virology. PMID 28679761 DOI: 10.1128/Jvi.00833-17  0.441
2017 Chatterjee S, Luthra P, Esaulova E, Agapov E, Yen BC, Borek DM, Edwards MR, Mittal A, Jordan DS, Ramanan P, Moore ML, Pappu RV, Holtzman MJ, Artyomov MN, Basler CF, et al. Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses. Nature Microbiology. 2: 17101. PMID 28665409 DOI: 10.1038/Nmicrobiol.2017.101  0.357
2017 Dilley KA, Voorhies AA, Luthra P, Puri V, Stockwell TB, Lorenzi H, Basler CF, Shabman RS. The Ebola virus VP35 protein binds viral immunostimulatory and host RNAs identified through deep sequencing. Plos One. 12: e0178717. PMID 28636653 DOI: 10.1371/Journal.Pone.0178717  0.406
2017 Xu W, Luthra P, Wu C, Batra J, Leung DW, Basler CF, Amarasinghe GK. Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis. Nature Communications. 8: 15576. PMID 28593988 DOI: 10.1038/Ncomms15576  0.402
2017 Luthra P, Basler CF. Assays to Measure Suppression of Type I Interferon Responses by Filovirus VP35 Proteins. Methods in Molecular Biology (Clifton, N.J.). 1628: 133-142. PMID 28573616 DOI: 10.1007/978-1-4939-7116-9_10  0.441
2017 Luthra P, Aguirre S, Yen BC, Pietzsch CA, Sanchez-Aparicio MT, Tigabu B, Morlock LK, García-Sastre A, Leung DW, Williams NS, Fernandez-Sesma A, Bukreyev A, Basler CF. Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion. Mbio. 8. PMID 28377530 DOI: 10.1128/Mbio.00368-17  0.443
2016 Edwards MR, Liu G, Mire CE, Sureshchandra S, Luthra P, Yen B, Shabman RS, Leung DW, Messaoudi I, Geisbert TW, Amarasinghe GK, Basler CF. Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins. Cell Reports. PMID 26876165 DOI: 10.1016/J.Celrep.2016.01.049  0.395
2015 Ciancanelli MJ, Huang SX, Luthra P, Garner H, Itan Y, Volpi S, Lafaille FG, Trouillet C, Schmolke M, Albrecht RA, Israelsson E, Lim HK, Casadio M, Hermesh T, Lorenzo L, et al. Infectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency. Science (New York, N.Y.). 348: 448-53. PMID 25814066 DOI: 10.1126/Science.Aaa1578  0.359
2015 Luthra P, Jordan DS, Leung DW, Amarasinghe GK, Basler CF. Ebola virus VP35 interaction with dynein LC8 regulates viral RNA synthesis. Journal of Virology. 89: 5148-53. PMID 25741013 DOI: 10.1128/Jvi.03652-14  0.386
2014 Brown CS, Lee MS, Leung DW, Wang T, Xu W, Luthra P, Anantpadma M, Shabman RS, Melito LM, MacMillan KS, Borek DM, Otwinowski Z, Ramanan P, Stubbs AJ, Peterson DS, et al. In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity. Journal of Molecular Biology. 426: 2045-58. PMID 24495995 DOI: 10.1016/J.Jmb.2014.01.010  0.423
2013 Binning JM, Wang T, Luthra P, Shabman RS, Borek DM, Liu G, Xu W, Leung DW, Basler CF, Amarasinghe GK. Development of RNA aptamers targeting Ebola virus VP35 Biochemistry. 52: 8406-8419. PMID 24067086 DOI: 10.1021/Bi400704D  0.38
2013 Luthra P, Ramanan P, Mire CE, Weisend C, Tsuda Y, Yen B, Liu G, Leung DW, Geisbert TW, Ebihara H, Amarasinghe GK, Basler CF. Mutual antagonism between the ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome Cell Host and Microbe. 14: 74-84. PMID 23870315 DOI: 10.1016/J.Chom.2013.06.010  0.478
2012 Xu P, Luthra P, Li Z, Fuentes S, D'Andrea JA, Wu J, Rubin S, Rota PA, He B. The V protein of mumps virus plays a critical role in pathogenesis. Journal of Virology. 86: 1768-76. PMID 22090137 DOI: 10.1128/Jvi.06019-11  0.642
2011 Sun D, Luthra P, Xu P, Yoon H, He B. Identification of a phosphorylation site within the P protein important for mRNA transcription and growth of parainfluenza virus 5. Journal of Virology. 85: 8376-85. PMID 21680523 DOI: 10.1128/Jvi.00618-11  0.664
2011 Luthra P, Sun D, Silverman RH, He B. Activation of IFN-β expression by a viral mRNA through RNase L and MDA5. Proceedings of the National Academy of Sciences of the United States of America. 108: 2118-23. PMID 21245317 DOI: 10.1073/Pnas.1012409108  0.65
2009 Sun D, Luthra P, Li Z, He B. PLK1 down-regulates parainfluenza virus 5 gene expression. Plos Pathogens. 5: e1000525. PMID 19629176 DOI: 10.1371/Journal.Ppat.1000525  0.659
2008 Luthra P, Sun D, Wolfgang M, He B. AKT1-dependent activation of NF-kappaB by the L protein of parainfluenza virus 5. Journal of Virology. 82: 10887-95. PMID 18715928 DOI: 10.1128/Jvi.00806-08  0.659
2007 Fuentes S, Tran KC, Luthra P, Teng MN, He B. Function of the respiratory syncytial virus small hydrophobic protein. Journal of Virology. 81: 8361-6. PMID 17494063 DOI: 10.1128/Jvi.02717-06  0.628
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