☰

Adam Frost, Ph.D. - Publications

Affiliations: 
2008 Yale University, New Haven, CT 
Area:
Biochemistry
Tree Info Similar researchers PubMed Report error

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 von der Malsburg A, Sapp GM, Zuccaro KE, von Appen A, Moss FR, Kalia R, Bennett JA, Abriata LA, Dal Peraro M, van der Laan M, Frost A, Aydin H. Structural mechanism of mitochondrial membrane remodelling by human OPA1. Nature. 620: 1101-1108. PMID 37612504 DOI: 10.1038/s41586-023-06441-6  0.721
2023 Moss FR, Lincoff J, Tucker M, Mohammed A, Grabe M, Frost A. Brominated lipid probes expose structural asymmetries in constricted membranes. Nature Structural & Molecular Biology. PMID 36624348 DOI: 10.1038/s41594-022-00898-1  0.702
2022 Manicki M, Aydin H, Abriata LA, Overmyer KA, Guerra RM, Coon JJ, Dal Peraro M, Frost A, Pagliarini DJ. Structure and functionality of a multimeric human COQ7:COQ9 complex. Molecular Cell. PMID 36306796 DOI: 10.1016/j.molcel.2022.10.003  0.373
2022 Boone M, Wang L, Lawrence R, Frost A, Walter P, Schoof M. A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation. Elife. 11. PMID 35416150 DOI: 10.7554/eLife.76171  0.405
2021 Schoof M, Wang L, Cogan JZ, Lawrence RE, Boone M, Wuerth JD, Frost A, Walter P. Viral evasion of the integrated stress response through antagonism of eIF2-P binding to eIF2B. Nature Communications. 12: 7103. PMID 34876554 DOI: 10.1038/s41467-021-26164-4  0.403
2021 Gupta M, Azumaya CM, Moritz M, Pourmal S, Diallo A, Merz GE, Jang G, Bouhaddou M, Fossati A, Brilot AF, Diwanji D, Hernandez E, Herrera N, Kratochvil HT, Lam VL, ... ... Frost A, et al. CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. Biorxiv : the Preprint Server For Biology. PMID 34013269 DOI: 10.1101/2021.05.10.443524  0.662
2021 Nguyen HC, Melo AA, Kruk J, Frost A, Gabruk M. Photocatalytic LPOR forms helical lattices that shape membranes for chlorophyll synthesis. Nature Plants. 7: 437-444. PMID 33875834 DOI: 10.1038/s41477-021-00885-2  0.375
2021 Schoof M, Boone M, Wang L, Lawrence R, Frost A, Walter P. eIF2B conformation and assembly state regulates the integrated stress response. Elife. 10. PMID 33688831 DOI: 10.7554/eLife.65703  0.404
2020 Miller-Vedam LE, Bräuning B, Popova KD, Schirle Oakdale NT, Bonnar JL, Prabu JR, Boydston EA, Sevillano N, Shurtleff MJ, Stroud RM, Craik CS, Schulman BA, Frost A, Weissman JS. Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients. Elife. 9. PMID 33236988 DOI: 10.7554/eLife.62611  0.462
2020 Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, ... ... Frost A, et al. Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science (New York, N.Y.). PMID 33060197 DOI: 10.1126/science.abe9403  0.63
2020 von Appen A, LaJoie D, Johnson IE, Trnka MJ, Pick SM, Burlingame AL, Ullman KS, Frost A. LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation. Nature. 582: 115-118. PMID 32494070 DOI: 10.1038/S41586-020-2232-X  0.41
2020 Moser von Filseck J, Barberi L, Talledge N, Johnson IE, Frost A, Lenz M, Roux A. Anisotropic ESCRT-III architecture governs helical membrane tube formation. Nature Communications. 11: 1516. PMID 32471995 DOI: 10.1038/S41467-020-15327-4  0.536
2020 Zhang R, Lee DM, Jimah JR, Gerassimov N, Yang C, Kim S, Luvsanjav D, Winkelman J, Mettlen M, Abrams ME, Kalia R, Keene P, Pandey P, Ravaux B, Kim JH, ... ... Frost A, et al. Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein. Nature Cell Biology. PMID 32451441 DOI: 10.1038/S41556-020-0519-7  0.385
2020 Nguyen HC, Talledge N, McCullough J, Sharma A, Moss FR, Iwasa JH, Vershinin MD, Sundquist WI, Frost A. Membrane constriction and thinning by sequential ESCRT-III polymerization. Nature Structural & Molecular Biology. PMID 32251413 DOI: 10.1038/s41594-020-0404-x  0.734
2020 Stojković V, Myasnikov AG, Young ID, Frost A, Fraser JS, Fujimori DG. Assessment of the nucleotide modifications in the high-resolution cryo-electron microscopy structure of the Escherichia coli 50S subunit. Nucleic Acids Research. PMID 31989172 DOI: 10.1093/Nar/Gkaa037  0.33
2020 Rossi G, Lepore D, Kenner L, Czuchra AB, Plooster M, Frost A, Munson M, Brennwald P. Exocyst structural changes associated with activation of tethering downstream of Rho/Cdc42 GTPases. The Journal of Cell Biology. 219. PMID 31904797 DOI: 10.1083/Jcb.201904161  0.404
2020 Munson M, Lepore D, Feyder M, Rossi G, Czuchra AB, Kenner L, Martínez-Núñez L, Frost A, Brennwald P. Activation of the Exocyst Tethering Complex for SNARE Complex Regulation and Membrane Fusion The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00212  0.424
2020 Munson M, Lepore D, Feyder M, Rossi G, Czuchra AB, Kenner L, Martinez-Nunez L, Forson JM, Frost A, Brennwald P. Exocyst Tethering Complex Regulation of SNARE Proteins and Membrane Fusion Biophysical Journal. 118: 340a-341a. DOI: 10.1016/J.Bpj.2019.11.1896  0.497
2019 Romanov V, McCullough J, Gale BK, Frost A. A Tunable Microfluidic Device Enables Cargo Encapsulation by Cell- or Organelle-Sized Lipid Vesicles Comprising Asymmetric Lipid Bilayers. Advanced Biosystems. 3. PMID 31428671 DOI: 10.1002/adbi.201900010  0.347
2019 Kalia R, Frost A. Open and cut: allosteric motion and membrane fission by dynamin superfamily proteins. Molecular Biology of the Cell. 30: 2097-2104. PMID 31365329 DOI: 10.1091/Mbc.E16-10-0709  0.5
2019 Kenner LR, Anand AA, Nguyen HC, Myasnikov AG, Klose CJ, McGeever LA, Tsai JC, Miller-Vedam LE, Walter P, Frost A. eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response. Science (New York, N.Y.). 364: 491-495. PMID 31048491 DOI: 10.1126/Science.Aaw2922  0.497
2019 Ruiz K, Thaker TM, Agnew C, Miller-Vedam L, Trenker R, Herrera C, Ingaramo M, Toso D, Frost A, Jura N. Functional role of PGAM5 multimeric assemblies and their polymerization into filaments. Nature Communications. 10: 531. PMID 30705304 DOI: 10.1038/s41467-019-08393-w  0.301
2019 Ruiz K, Thaker TM, Agnew C, Miller-Vedam L, Trenker R, Herrera C, Ingaramo M, Toso D, Frost A, Jura N. Functional role of PGAM5 multimeric assemblies and their polymerization into filaments. Nature Communications. 10: 531-531. DOI: 10.2210/Pdb6Cni/Pdb  0.41
2019 Nguyen HC, Talledge N, McCullough J, Sundquist WI, Frost A. The Structural Basis of a Membrane-Bound ESCRT-III Helical Assembly Biophysical Journal. 116: 180a. DOI: 10.1016/J.Bpj.2018.11.1000  0.499
2018 McCullough J, Frost A, Sundquist WI. Structures, Functions, and Dynamics of ESCRT-III/Vps4 Membrane Remodeling and Fission Complexes. Annual Review of Cell and Developmental Biology. PMID 30095293 DOI: 10.1146/Annurev-Cellbio-100616-060600  0.484
2018 Kalia R, Wang RY, Yusuf A, Thomas PV, Agard DA, Shaw JM, Frost A. Structural basis of mitochondrial receptor binding and constriction by DRP1. Nature. PMID 29899447 DOI: 10.1038/S41586-018-0211-2  0.366
2018 Zurita Rendón O, Fredrickson EK, Howard CJ, Van Vranken J, Fogarty S, Tolley ND, Kalia R, Osuna BA, Shen PS, Hill CP, Frost A, Rutter J. Vms1p is a release factor for the ribosome-associated quality control complex. Nature Communications. 9: 2197. PMID 29875445 DOI: 10.1038/S41467-018-04564-3  0.32
2018 Shurtleff MJ, Itzhak DN, Hussmann JA, Schirle Oakdale NT, Costa EA, Jonikas M, Weibezahn J, Popova KD, Jan CH, Sinitcyn P, Vembar SS, Hernandez H, Cox J, Burlingame AL, Brodsky J, ... Frost A, et al. The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins. Elife. 7. PMID 29809151 DOI: 10.7554/Elife.37018  0.509
2018 Tsai JC, Miller-Vedam LE, Anand AA, Jaishankar P, Nguyen HC, Renslo AR, Frost A, Walter P. Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule. Science (New York, N.Y.). 359. PMID 29599213 DOI: 10.1126/Science.Aaq0939  0.48
2018 Shurtleff MJ, Itzhak DN, Hussmann JA, Oakdale NTS, Costa EA, Jonikas M, Weibezahn J, Popova KD, Jan CH, Sinitcyn P, Vembar SS, Hernandez H, Cox J, Burlingame AL, Brodsky JL, ... Frost A, et al. Author response: The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins Elife. DOI: 10.7554/Elife.37018.023  0.502
2017 Hohendahl A, Talledge N, Galli V, Shen PS, Humbert F, De Camilli P, Frost A, Roux A. Structural inhibition of dynamin-mediated membrane fission by endophilin. Elife. 6. PMID 28933693 DOI: 10.7554/Elife.26856  0.547
2017 Osuna BA, Howard CJ, Kc S, Frost A, Weinberg DE. In vitro analysis of RQC activities provides insights into the mechanism and function of CAT tailing. Elife. 6. PMID 28718767 DOI: 10.7554/Elife.27949  0.356
2017 Gu M, LaJoie D, Chen OS, von Appen A, Ladinsky MS, Redd MJ, Nikolova L, Bjorkman PJ, Sundquist WI, Ullman KS, Frost A. LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28242692 DOI: 10.1073/Pnas.1613916114  0.44
2017 Hohendahl A, Talledge N, Galli V, Shen PS, Humbert F, Camilli PD, Frost A, Roux A. Author response: Structural inhibition of dynamin-mediated membrane fission by endophilin Elife. DOI: 10.7554/Elife.26856.018  0.459
2016 McBride HM, Frost A. Cell biology: Double agents for mitochondrial division. Nature. PMID 27880759 DOI: 10.1038/Nature20482  0.309
2016 Antonny B, Burd C, De Camilli P, Chen E, Daumke O, Faelber K, Ford M, Frolov VA, Frost A, Hinshaw JE, Kirchhausen T, Kozlov MM, Lenz M, Low HH, McMahon H, et al. Membrane fission by dynamin: what we know and what we need to know. The Embo Journal. PMID 27670760 DOI: 10.15252/Embj.201694613  0.467
2016 Hwang J, Ribbens D, Raychaudhuri S, Cairns L, Gu H, Frost A, Urban S, Espenshade PJ. A Golgi rhomboid protease Rbd2 recruits Cdc48 to cleave yeast SREBP. The Embo Journal. PMID 27655872 DOI: 10.15252/Embj.201693923  0.431
2015 Heider MR, Gu M, Duffy CM, Mirza AM, Marcotte LL, Walls AC, Farrall N, Hakhverdyan Z, Field MC, Rout MP, Frost A, Munson M. Subunit connectivity, assembly determinants and architecture of the yeast exocyst complex. Nature Structural & Molecular Biology. PMID 26656853 DOI: 10.1038/Nsmb.3146  0.335
2015 McCullough J, Clippinger AK, Talledge N, Skowyra ML, Saunders MG, Naismith TV, Colf LA, Afonine P, Arthur C, Sundquist WI, Hanson PI, Frost A. Structure and membrane remodeling activity of ESCRT-III helical polymers. Science (New York, N.Y.). PMID 26634441 DOI: 10.1126/Science.Aad8305  0.532
2015 Kalia R, Talledge N, Frost A. Structural and functional studies of membrane remodeling machines. Methods in Cell Biology. 128: 165-200. PMID 25997348 DOI: 10.1016/Bs.Mcb.2015.02.007  0.513
2015 Shen PS, Park J, Qin Y, Li X, Parsawar K, Larson MH, Cox J, Cheng Y, Lambowitz AM, Weissman JS, Brandman O, Frost A. Protein synthesis. Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains. Science (New York, N.Y.). 347: 75-8. PMID 25554787 DOI: 10.1126/Science.1259724  0.34
2015 McCullough J, Saunders M, Colf L, Sundquist W, Frost A. Structure and Function of Membrane-Remodeling ESCRT-III Assemblies Biophysical Journal. 108: 358a. DOI: 10.1016/J.Bpj.2014.11.1960  0.529
2015 Kalia R, Talledge N, Frost A. Structural and functional studies of membrane remodeling machines Methods in Cell Biology. DOI: 10.1016/bs.mcb.2015.02.007  0.341
2013 Koirala S, Guo Q, Kalia R, Bui HT, Eckert DM, Frost A, Shaw JM. Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission. Proceedings of the National Academy of Sciences of the United States of America. 110: E1342-51. PMID 23530241 DOI: 10.1073/Pnas.1300855110  0.489
2012 Brandman O, Stewart-Ornstein J, Wong D, Larson A, Williams CC, Li GW, Zhou S, King D, Shen PS, Weibezahn J, Dunn JG, Rouskin S, Inada T, Frost A, Weissman JS. A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress. Cell. 151: 1042-54. PMID 23178123 DOI: 10.1016/J.Cell.2012.10.044  0.319
2012 Frost A, Elgort MG, Brandman O, Ives C, Collins SR, Miller-Vedam L, Weibezahn J, Hein MY, Poser I, Mann M, Hyman AA, Weissman JS. Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions. Cell. 149: 1339-52. PMID 22682253 DOI: 10.1016/J.Cell.2012.04.028  0.402
2012 Mim C, Cui H, Gawronski-Salerno JA, Frost A, Lyman E, Voth GA, Unger VM. Structural basis of membrane bending by the N-BAR protein endophilin. Cell. 149: 137-45. PMID 22464326 DOI: 10.1016/J.Cell.2012.01.048  0.707
2012 Mim C, Gawronski-Salerno J, Unger V, Frost A. Visualizing BAR-Dependent Membrane Remodeling Microscopy and Microanalysis. 18: 44-45. DOI: 10.1017/S1431927612002073  0.664
2011 Frost A. Membrane trafficking: decoding vesicle identity with contrasting chemistries. Current Biology : Cb. 21: R811-3. PMID 21996503 DOI: 10.1016/J.Cub.2011.08.045  0.458
2009 Guerrier S, Coutinho-Budd J, Sassa T, Gresset A, Jordan NV, Chen K, Jin WL, Frost A, Polleux F. The F-BAR domain of srGAP2 induces membrane protrusions required for neuronal migration and morphogenesis. Cell. 138: 990-1004. PMID 19737524 DOI: 10.1016/J.Cell.2009.06.047  0.393
2009 Frost A, Unger VM, De Camilli P. The BAR domain superfamily: membrane-molding macromolecules. Cell. 137: 191-6. PMID 19379681 DOI: 10.1016/J.Cell.2009.04.010  0.722
2008 Frost A, Perera R, Roux A, Spasov K, Destaing O, Egelman EH, De Camilli P, Unger VM. Structural basis of membrane invagination by F-BAR domains. Cell. 132: 807-17. PMID 18329367 DOI: 10.1016/J.Cell.2007.12.041  0.714
2007 Frost A, De Camilli P, Unger VM. F-BAR proteins join the BAR family fold. Structure (London, England : 1993). 15: 751-3. PMID 17637334 DOI: 10.1016/J.Str.2007.06.006  0.644
2006 Roux A, Uyhazi K, Frost A, De Camilli P. GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission. Nature. 441: 528-31. PMID 16648839 DOI: 10.1038/Nature04718  0.417
Show low-probability matches.