Alberto Machado, Ph.D. - Publications

Affiliations: 
University of Sevilla, Sevilla, Andalucía, Spain 

129 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Tayara K, Espinosa-Oliva AM, García-Domínguez I, Ismaiel AA, Boza-Serrano A, Deierborg T, Machado A, Herrera AJ, Venero JL, de Pablos RM. Divergent Effects of Metformin on an Inflammatory Model of Parkinson's Disease. Frontiers in Cellular Neuroscience. 12: 440. PMID 30519161 DOI: 10.3389/Fncel.2018.00440  0.326
2016 Sánchez-Hidalgo AC, Muñoz MF, Herrera AJ, Espinosa-Oliva AM, Stowell R, Ayala A, Machado A, Venero JL, de Pablos RM. Chronic stress alters the expression levels of longevity-related genes in the rat hippocampus. Neurochemistry International. PMID 27120255 DOI: 10.1016/J.Neuint.2016.04.009  0.305
2014 de Pablos RM, Herrera AJ, Espinosa-Oliva AM, Sarmiento M, Muñoz MF, Machado A, Venero JL. Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation. Journal of Neuroinflammation. 11: 34. PMID 24565378 DOI: 10.1186/1742-2094-11-34  0.318
2014 Espinosa-Oliva AM, de Pablos RM, Sarmiento M, Villarán RF, Carrillo-Jiménez A, Santiago M, Venero JL, Herrera AJ, Cano J, Machado A. Role of dopamine in the recruitment of immune cells to the nigro-striatal dopaminergic structures. Neurotoxicology. 41: 89-101. PMID 24486959 DOI: 10.1016/J.Neuro.2014.01.006  0.4
2012 Argüelles S, Muñoz MF, Cano M, Machado A, Ayala A. In vitro and in vivo protection by melatonin against the decline of elongation factor-2 caused by lipid peroxidation: preservation of protein synthesis. Journal of Pineal Research. 53: 1-10. PMID 22462727 DOI: 10.1111/J.1600-079X.2011.00961.X  0.339
2012 Hernández-Romero MC, Delgado-Cortés MJ, Sarmiento M, de Pablos RM, Espinosa-Oliva AM, Argüelles S, Bández MJ, Villarán RF, Mauriño R, Santiago M, Venero JL, Herrera AJ, Cano J, Machado A. Peripheral inflammation increases the deleterious effect of CNS inflammation on the nigrostriatal dopaminergic system. Neurotoxicology. 33: 347-60. PMID 22330755 DOI: 10.1016/J.Neuro.2012.01.018  0.35
2011 Machado A, Herrera AJ, Venero JL, Santiago M, Pablos RMd, Villarán RF, Espinosa-Oliva AM, Argüelles S, Sarmiento M, Delgado-Cortés MJ, Mauriño R, Cano J. Inflammatory animal model for parkinson’s disease: the intranigral injection of LPS induced the inflammatory process along with the selective degeneration of nigrostriatal dopaminergic neurons International Scholarly Research Notices. 2011: 476158-476158. PMID 22389821 DOI: 10.5402/2011/476158  0.336
2011 Argüelles S, Cano M, Machado A, Ayala A. Effect of aging and oxidative stress on elongation factor-2 in hypothalamus and hypophysis. Mechanisms of Ageing and Development. 132: 55-64. PMID 21172375 DOI: 10.1016/J.Mad.2010.12.002  0.36
2011 Espinosa-Oliva AM, de Pablos RM, Villarán RF, Argüelles S, Venero JL, Machado A, Cano J. Stress is critical for LPS-induced activation of microglia and damage in the rat hippocampus Neurobiology of Aging. 32: 85-102. PMID 19286276 DOI: 10.1016/J.Neurobiolaging.2009.01.012  0.32
2011 MacHado A, Herrera AJ, Venero JL, Santiago M, De Pablos RM, Villarán RF, Espinosa-Oliva AM, Argüelles S, Sarmiento M, Delgado-Cortés MJ, Maurio R, Cano J. Peripheral inflammation increases the damage in animal models of nigrostriatal dopaminergic neurodegeneration: Possible implication in parkinson's disease incidence Parkinson's Disease. DOI: 10.4061/2011/393769  0.32
2010 Venero JL, Mauriño R, Machado A, Santiago M. Striatal ablation of GABAergic neurons prevents the in vivo neuroprotective effect of DCG-IV against the MPP+-induced neurotoxicity on dopaminergic nerve terminals. Neurochemistry International. 57: 979-84. PMID 20974202 DOI: 10.1016/J.Neuint.2010.10.009  0.367
2010 Arguelles S, Cano M, Machado A, Ayala A. Comparative study of the in vitro protective effects of several antioxidants on elongation factor 2 under oxidative stress conditions. Bioscience, Biotechnology, and Biochemistry. 74: 1373-9. PMID 20622459 DOI: 10.1271/Bbb.100054  0.363
2010 Villarán RF, Espinosa-Oliva AM, Sarmiento M, De Pablos RM, Argüelles S, Delgado-Cortés MJ, Sobrino V, Van Rooijen N, Venero JL, Herrera AJ, Cano J, Machado A. Ulcerative colitis exacerbates lipopolysaccharide-induced damage to the nigral dopaminergic system: potential risk factor in Parkinson`s disease. Journal of Neurochemistry. 114: 1687-700. PMID 20584104 DOI: 10.1111/J.1471-4159.2010.06879.X  0.326
2010 Mauriño R, Machado A, Santiago M. Effect of in vivo striatal perfusion of lipopolysaccharide on dopamine metabolites. Neuroscience Letters. 475: 121-3. PMID 20347938 DOI: 10.1016/J.Neulet.2010.03.050  0.412
2010 Argüelles S, Herrera AJ, Carreño-Müller E, de Pablos RM, Villarán RF, Espinosa-Oliva AM, Machado A, Cano J. Degeneration of dopaminergic neurons induced by thrombin injection in the substantia nigra of the rat is enhanced by dexamethasone: role of monoamine oxidase enzyme. Neurotoxicology. 31: 55-66. PMID 19969022 DOI: 10.1016/J.Neuro.2009.12.001  0.389
2009 Argüelles S, Machado A, Ayala A. Adduct formation of 4-hydroxynonenal and malondialdehyde with elongation factor-2 in vitro and in vivo. Free Radical Biology & Medicine. 47: 324-30. PMID 19447174 DOI: 10.1016/J.Freeradbiomed.2009.05.010  0.368
2009 Villarán RF, de Pablos RM, Argüelles S, Espinosa-Oliva AM, Tomás-Camardiel M, Herrera AJ, Cano J, Machado A. The intranigral injection of tissue plasminogen activator induced blood-brain barrier disruption, inflammatory process and degeneration of the dopaminergic system of the rat. Neurotoxicology. 30: 403-13. PMID 19442825 DOI: 10.1016/J.Neuro.2009.02.011  0.365
2009 Santiago M, Hernández-Romero MC, Machado A, Cano J. Zocor Forte (simvastatin) has a neuroprotective effect against LPS striatal dopaminergic terminals injury, whereas against MPP+ does not. European Journal of Pharmacology. 609: 58-64. PMID 19292984 DOI: 10.1016/J.Ejphar.2009.03.026  0.353
2008 Herrera AJ, de Pablos RM, Carreño-Müller E, Villarán RF, Venero JL, Tomás-Camardiel M, Cano J, Machado A. The intrastriatal injection of thrombin in rat induced a retrograde apoptotic degeneration of nigral dopaminergic neurons through synaptic elimination. Journal of Neurochemistry. 105: 750-62. PMID 18179476 DOI: 10.1111/J.1471-4159.2007.05170.X  0.379
2008 Villarán RF, Tomás-Camardiel M, de Pablos RM, Santiago M, Herrera AJ, Navarro A, Machado A, Cano J. Endogenous dopamine enhances the neurotoxicity of 3-nitropropionic acid in the striatum through the increase of mitochondrial respiratory inhibition and free radicals production. Neurotoxicology. 29: 244-58. PMID 18093658 DOI: 10.1016/J.Neuro.2007.11.001  0.402
2008 Hernández-Romero MC, Argüelles S, Villarán RF, de Pablos RM, Delgado-Cortés MJ, Santiago M, Herrera AJ, Cano J, Machado A. Simvastatin prevents the inflammatory process and the dopaminergic degeneration induced by the intranigral injection of lipopolysaccharide. Journal of Neurochemistry. 105: 445-59. PMID 18047562 DOI: 10.1111/J.1471-4159.2007.05148.X  0.341
2007 Argüelles S, Gómez A, Machado A, Ayala A. A preliminary analysis of within-subject variation in human serum oxidative stress parameters as a function of time. Rejuvenation Research. 10: 621-36. PMID 18047415 DOI: 10.1089/Rej.2006.0528  0.306
2007 Argüelles S, Machado A, Ayala A. 'In vitro' protective effect of a hydrophilic vitamin E analogue on the decrease in levels of elongation factor 2 in conditions of oxidative stress. Gerontology. 53: 282-8. PMID 17510559 DOI: 10.1159/000102948  0.317
2007 Rite I, Machado A, Cano J, Venero JL. Blood-brain barrier disruption induces in vivo degeneration of nigral dopaminergic neurons. Journal of Neurochemistry. 101: 1567-82. PMID 17437543 DOI: 10.1111/J.1471-4159.2007.04567.X  0.303
2006 De Pablos RM, Villarán RF, Argüelles S, Herrera AJ, Venero JL, Ayala A, Cano J, Machado A. Stress increases vulnerability to inflammation in the rat prefrontal cortex Journal of Neuroscience. 26: 5709-5719. PMID 16723527 DOI: 10.1523/Jneurosci.0802-06.2006  0.356
2006 Argüelles S, Machado A, Ayala A. "In vitro" effect of lipid peroxidation metabolites on elongation factor-2. Biochimica Et Biophysica Acta. 1760: 445-52. PMID 16469450 DOI: 10.1016/J.Bbagen.2005.12.019  0.305
2005 de Pablos RM, Herrera AJ, Tomás-Camardiel M, Machado A, Cano J. Deprenyl enhances the striatal neuronal damage produced by quinolinic acid. Brain Research. Molecular Brain Research. 141: 48-57. PMID 16202473 DOI: 10.1016/J.Molbrainres.2005.08.007  0.4
2005 Tomás-Camardiel M, Venero JL, Herrera AJ, De Pablos RM, Pintor-Toro JA, Machado A, Cano J. Blood-brain barrier disruption highly induces aquaporin-4 mRNA and protein in perivascular and parenchymal astrocytes: Protective effect by estradiol treatment in ovariectomized animals Journal of Neuroscience Research. 80: 235-246. PMID 15772982 DOI: 10.1002/Jnr.20443  0.304
2005 Rite I, Machado A, Cano J, Venero JL. Divergent regulatory mechanisms governing BDNF mRNA expression in cerebral cortex and substantia nigra in response to striatal target ablation. Experimental Neurology. 192: 142-55. PMID 15698628 DOI: 10.1016/J.Expneurol.2004.11.005  0.317
2005 De Pablos RM, Herrera AJ, Villarán RF, Cano J, Machado A. Dopamine-dependent neurotoxicity of lipopolysaccharide in substantia nigra. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 407-9. PMID 15625078 DOI: 10.1096/Fj.04-2153Fje  0.42
2004 Tomás-Camardiel M, Rite I, Herrera AJ, de Pablos RM, Cano J, Machado A, Venero JL. Minocycline reduces the lipopolysaccharide-induced inflammatory reaction, peroxynitrite-mediated nitration of proteins, disruption of the blood-brain barrier, and damage in the nigral dopaminergic system. Neurobiology of Disease. 16: 190-201. PMID 15207276 DOI: 10.1016/J.Nbd.2004.01.010  0.371
2003 Romero-Ramos M, Venero JL, Garcia-Rodriguez S, Ayala A, Machado A, Cano J. Semichronic inhibition of glutathione reductase promotes oxidative damage to proteins and induces both transcription and translation of tyrosine hydroxylase in the nigrostriatal system. Free Radical Research. 37: 1003-12. PMID 14670008 DOI: 10.1080/10715760310001598574  0.691
2003 Parrado J, Absi EH, Machado A, Ayala A. "In vitro" effect of cumene hydroperoxide on hepatic elongation factor-2 and its protection by melatonin Biochimica Et Biophysica Acta - General Subjects. 1624: 139-144. PMID 14642824 DOI: 10.1016/J.Bbagen.2003.10.006  0.307
2003 Rite I, Venero JL, Tomás-Camardiel M, Machado A, Cano J. Expression of BDNF mRNA in substantia nigra is dependent on target integrity and independent of neuronal activation. Journal of Neurochemistry. 87: 709-21. PMID 14535953 DOI: 10.1046/J.1471-4159.2003.02041.X  0.332
2003 Carreño-Müller E, Herrera AJ, de Pablos RM, Tomás-Camardiel M, Venero JL, Cano J, Machado A. Thrombin induces in vivo degeneration of nigral dopaminergic neurones along with the activation of microglia. Journal of Neurochemistry. 84: 1201-14. PMID 12603843 DOI: 10.1046/J.1471-4159.2003.01634.X  0.369
2003 Venero JL, Revuelta M, Atiki L, Santiago M, Toms-Camardiel MC, Cano J, Machado A. Evidence for dopamine-derived hydroxyl radical formation in the nigrostriatal system in response to axotomy. Free Radical Biology & Medicine. 34: 111-23. PMID 12498986 DOI: 10.1016/S0891-5849(02)01191-7  0.418
2002 Absi E, Parrado J, Ayala A, Machado A. Decrease of 1-methyl-1,2,3,4-tetrahydroisoquinoline synthesizing enzyme activity in the brain areas of aged rat. Brain Research. 955: 161-3. PMID 12419532 DOI: 10.1016/S0006-8993(02)03428-5  0.376
2002 Tomás-Camardiel M, Herrera AJ, Venero JL, Cruz Sánchez-Hidalgo M, Cano J, Machado A. Differential regulation of glutamic acid decarboxylase mRNA and tyrosine hydroxylase mRNA expression in the aged manganese-treated rats. Brain Research. Molecular Brain Research. 103: 116-29. PMID 12106697 DOI: 10.1016/S0169-328X(02)00192-4  0.455
2002 Venero JL, Absi el-H, Cano J, Machado A. Melatonin induces tyrosine hydroxylase mRNA expression in the ventral mesencephalon but not in the hypothalamus. Journal of Pineal Research. 32: 6-14. PMID 11841594 DOI: 10.1034/J.1600-079X.2002.10813.X  0.398
2002 Tomas-Camardiel M, Sanchez-Hidalgo MC, Sanchez del Pino MJ, Navarro A, Machado A, Cano J. Comparative study of the neuroprotective effect of dehydroepiandrosterone and 17β-estradiol against 1-methyl-4-phenylpyridium toxicity on rat striatum Neuroscience. 109: 569-584. PMID 11823067 DOI: 10.1016/S0306-4522(01)00502-4  0.36
2002 Ruano D, Benavides J, Machado A, Vitorica J. Aging‐Associated Changes in the Pharmacological Properties of the Benzodiazepine (ω) Receptor Isotypes in the Rat Hippocampus Journal of Neurochemistry. 64: 867-873. PMID 7830081 DOI: 10.1046/J.1471-4159.1995.64020867.X  0.311
2001 Matarredona ER, Santiago M, Venero JL, Cano J, Machado A. Group II metabotropic glutamate receptor activation protects striatal dopaminergic nerve terminals against MPP+-induced neurotoxicity along with brain-derived neurotrophic factor induction Journal of Neurochemistry. 76: 351-360. PMID 11208898 DOI: 10.1046/J.1471-4159.2001.00056.X  0.375
2000 Romero-Ramos M, Venero JL, Cano J, Machado A. Low selenium diet induces tyrosine hydroxylase enzyme in nigrostriatal system of the rat. Brain Research. Molecular Brain Research. 84: 7-16. PMID 11113527 DOI: 10.1016/S0169-328X(00)00171-6  0.707
2000 Romero-Ramos M, Venero JL, Santiago M, Rodriguez-Gómez JA, Vizuete ML, Cano J, Machado A. Decreased messenger RNA expression of key markers of the nigrostriatal dopaminergic system following vitamin E deficiency in the rat. Neuroscience. 101: 1029-36. PMID 11113352 DOI: 10.1016/S0306-4522(00)00424-3  0.657
2000 Absi E, Ayala A, Machado A, Parrado J. Protective effect of melatonin against the 1-methyl-4-phenylpyridinium-induced inhibition of Complex I of the mitochondrial respiratory chain Journal of Pineal Research. 29: 40-47. PMID 10949539 DOI: 10.1034/J.1600-079X.2000.290106.X  0.32
2000 Vizuete ML, Merino M, Venero JL, Santiago M, Cano J, Machado A. Histamine infusion induces a selective dopaminergic neuronal death along with an inflammatory reaction in rat substantia nigra Journal of Neurochemistry. 75: 540-552. PMID 10899929 DOI: 10.1046/j.1471-4159.2000.0750540.x  0.305
2000 Parrado J, Absi E, Ayala A, Castaño A, Cano J, Machado A. The endogenous amine 1-methyl-1,2,3,4-tetrahydroisoquinoline prevents the inhibition of complex I of the respiratory chain produced by MPP+ Journal of Neurochemistry. 75: 65-71. PMID 10854248 DOI: 10.1046/J.1471-4159.2000.0750065.X  0.328
2000 Santiago M, Matarredona ER, Granero L, Cano J, Machado A. Neurotoxic relationship between dopamine and iron in the striatal dopaminergic nerve terminals Brain Research. 858: 26-32. PMID 10700592 DOI: 10.1016/S0006-8993(99)02485-3  0.346
1999 Parrado J, Bougria M, Ayala A, MacHado A. Induced mono-(ADP)-ribosylation of rat liver cytosolic proteins by lipid peroxidant agents Free Radical Biology and Medicine. 26: 1079-1084. PMID 10381176 DOI: 10.1016/S0891-5849(98)00316-5  0.342
1999 Parrado J, Bougria M, Ayala A, Castaño A, Machado A. Effects of aging on the various steps of protein synthesis: Fragmentation of elongation factor 2 Free Radical Biology and Medicine. 26: 362-370. PMID 9895228 DOI: 10.1016/S0891-5849(98)00202-0  0.368
1998 Santiago M, Matarredona ER, Machado A, Cano J. Influence of serotoninergic drugs on in vivo dopamine extracellular output in rat striatum Journal of Neuroscience Research. 52: 591-598. PMID 9632315 DOI: 10.1002/(Sici)1097-4547(19980601)52:5<591::Aid-Jnr11>3.0.Co;2-5  0.307
1998 Castaño A, Herrera AJ, Cano J, Machado A. Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system Journal of Neurochemistry. 70: 1584-1592. PMID 9580157 DOI: 10.1046/j.1471-4159.1998.70041584.x  0.315
1997 Matarredona ER, Santiago M, Cano J, MacHado A. Involvement of iron in MPP+ toxicity in substantia nigra: Protection by desferrioxamine Brain Research. 773: 76-81. PMID 9409707 DOI: 10.1016/S0006-8993(97)00911-6  0.336
1997 Rodríguez-Gómez JA, Romero-Ramos M, Vizuete ML, Venero JL, Cano J, Machado A. Increased activity and expression of tyrosine hydroxylase in the rat substantia nigra after chronic treatment with nomifensine. Molecular Pharmacology. 52: 641-7. PMID 9380027 DOI: 10.1124/Mol.52.4.641  0.693
1997 Revuelta M, Venero JL, Machado A, Cano J. Deprenyl induces GFAP immunoreactivity in the intact and injured dopaminergic nigrostriatal system but fails to counteract axotomy-induced degenerative changes Glia. 21: 204-216. PMID 9336235 DOI: 10.1002/(Sici)1098-1136(199710)21:2<204::Aid-Glia4>3.0.Co;2-6  0.402
1997 Vizuete ML, Merino M, Cano J, Machado A. In vivo protection of striatal dopaminergic system against 1-methyl-4- phenylpyridinium neurotoxicity by phenobarbital Journal of Neuroscience Research. 49: 301-308. PMID 9260741 DOI: 10.1002/(Sici)1097-4547(19970801)49:3<301::Aid-Jnr5>3.0.Co;2-G  0.457
1997 Matarredona ER, Santiago M, Machado A, Cano J. Lack of involvement of glutamate-induced excitotoxicity in MPP+ toxicity in striatal dopaminergic terminals: Possible involvement of ascorbate British Journal of Pharmacology. 121: 1038-1044. PMID 9222565 DOI: 10.1038/Sj.Bjp.0701216  0.367
1997 De La Cruz CP, Revilla E, Rodríguez-Gómez JA, Vizuete ML, Cano J, MacHado A. (-)-Deprenyl treatment restores serum insulin-like growth factor-I (IGF-I) levels in aged rats to young rat level European Journal of Pharmacology. 327: 215-220. PMID 9200562 DOI: 10.1016/S0014-2999(97)89663-X  0.411
1997 Rodrïguez-Gômez JA, Venero JL, Vizuete ML, Cano J, Machado A. Deprenyl induces the tyrosine hydroxylase enzyme in the rat dopaminergic nigrostriatal system Molecular Brain Research. 46: 31-38. PMID 9191076 DOI: 10.1016/S0169-328X(96)00270-7  0.485
1997 Venero JL, Revuelta M, Cano J, Machado A. Time course changes in the dopaminergic nigrostriatal system following transection of the medial forebrain bundle: Detection of oxidatively modified proteins in substantia nigra Journal of Neurochemistry. 68: 2458-2468. PMID 9166740 DOI: 10.1046/J.1471-4159.1997.68062458.X  0.385
1997 Romero-Ramos M, Rodríguez-Gómez JA, Venero JL, Cano J, Machado A. Chronic inhibition of the high-affinity dopamine uptake system increases oxidative damage to proteins in the aged rat substantia nigra. Free Radical Biology & Medicine. 23: 1-7. PMID 9165291 DOI: 10.1016/S0891-5849(96)00405-4  0.709
1997 Castaño A, Ayala A, Rodríguez-Gómez JA, Herrera AJ, Cano J, Machado A. Low selenium diet increases the dopamine turnover in prefrontal cortex of the rat Neurochemistry International. 30: 549-555. PMID 9152996 DOI: 10.1016/S0197-0186(96)00123-4  0.458
1997 Revuelta M, Romero-Ramos M, Venero JL, Millan F, Machado A, Cano J. Less induced 1-methyl-4-phenylpyridinium ion neurotoxicity on striatal slices from guinea-pigs fed with a vitamin C-deficient diet. Neuroscience. 77: 167-74. PMID 9044384 DOI: 10.1016/S0306-4522(96)00491-5  0.662
1997 De La Cruz CP, Revilla E, Venero JL, Ayala A, Cano J, Machado A. Oxidative inactivation of tyrosine hydroxylase in substantia nigra of aged rat. Free Radical Biology & Medicine. 20: 53-61. PMID 8903679 DOI: 10.1016/0891-5849(95)02025-X  0.33
1996 Venero JL, Santiago M, Machado A, Cano J. MK-801 partially protects against the acute MPP+ depleting effect on dopamine levels in rat striatal slices Neurochemistry International. 29: 411-416. PMID 8939450 DOI: 10.1016/0197-0186(95)00163-8  0.422
1996 Ayala A, Parrado J, Bougria M, Machado A. Effect of oxidative stress, produced by cumene hydroperoxide, on the various steps of protein synthesis. Modifications of elongation factor-2 Journal of Biological Chemistry. 271: 23105-23110. PMID 8798501 DOI: 10.1074/Jbc.271.38.23105  0.334
1996 Santiago M, Machado A, Cano J. Nigral and striatal comparative study of the neurotoxic action of 1-methyl-4-phenylpyridinium ion: Involvement of dopamine uptake system Journal of Neurochemistry. 66: 1182-1190. PMID 8769882 DOI: 10.1046/J.1471-4159.1996.66031182.X  0.402
1996 De La Cruz CP, Revilla E, Steffen V, Rodríguez-Gómez JA, Cano J, Machado A. Protection of the aged substantia nigra of the rat against oxidative damage by (-)-deprenyl British Journal of Pharmacology. 117: 1756-1760. PMID 8732287 DOI: 10.1111/J.1476-5381.1996.Tb15350.X  0.39
1996 Alvarez E, Machado A, Sobrino F, Maria CS. Nitric oxide and superoxide anion production decrease with age in resident and activated rat peritoneal macrophages Cellular Immunology. 169: 152-155. PMID 8612288 DOI: 10.1006/Cimm.1996.0103  0.354
1996 Castaño A, Ayala A, Rodriguez-Gomez JA, de la Cruz CP, Revilla E, Cano J, Machado A. Increase in dopamine turnover and tyrosine hydroxylase enzyme in hippocampus of rats fed on low selenium diet. Journal of Neuroscience Research. 42: 684-91. PMID 8600301 DOI: 10.1002/JNR.490420511  0.348
1995 Bougria M, Vitorica J, Cano J, Machado A. Implication of dopamine transporter system on 1-methyl-4-phenylpyridinium and rotenone effect in striatal synaptosomes. European Journal of Pharmacology. 291: 407-415. PMID 8719427 DOI: 10.1016/0922-4106(95)90083-7  0.406
1995 Steffen V, Santiago M, de la Cruz CP, Revilla E, Machado A, Cano J. Effect of intraventricular injection of 1-methyl-4-phenylpyridinium: protection by acetyl-L-carnitine. Human & Experimental Toxicology. 14: 865-71. PMID 8588946 DOI: 10.1177/096032719501401102  0.311
1995 Santiago M, Granero L, Machado A, Cano J. Complex I inhibitor effect on the nigral and striatal release of dopamine in the presence and absence of nomifensine. European Journal of Pharmacology. 280: 251-256. PMID 8566093 DOI: 10.1016/0014-2999(95)00202-V  0.412
1995 Santiago M, Machado A, Cano J. 5-HT3 receptor agonist induced carrier-mediated release of dopamine in rat striatum in vivo British Journal of Pharmacology. 116: 1545-1550. PMID 8564217 DOI: 10.1111/J.1476-5381.1995.Tb16371.X  0.389
1995 Alvarez E, Conde M, Machado A, Sobrino F, Maria CS. Decrease in free-radical production with age in rat peritoneal macrophages. Biochemical Journal. 312: 555-560. PMID 8526870 DOI: 10.1042/Bj3120555  0.32
1995 Venero JL, Romero-Ramos M, Revuelta M, Machado A, Cano J. Intrastriatal quinolinic acid injections protect against 6-hydroxydopamine-induced lesions of the dopaminergic nigrostriatal system. Brain Research. 672: 153-8. PMID 7749737 DOI: 10.1016/0006-8993(94)01368-R  0.682
1995 Rodríguez-Gómez JA, Roza Cdl, Machado A, Cano J. The effect of age on the monoamines of the hypothalamus Mechanisms of Ageing and Development. 77: 185-195. PMID 7739266 DOI: 10.1016/0047-6374(94)01525-Q  0.379
1995 Maria CS, Revilla E, Ayala A, Cruz CPdl, Machado A. Changes in the histidine residues of Cu/Zn superoxide dismutase during aging. Febs Letters. 374: 85-88. PMID 7589519 DOI: 10.1016/0014-5793(95)01083-Q  0.307
1994 Steffen V, Vizuete ML, Machado A, Cano J. The effect of a vitamin E-deficient diet on amino acid levels in the substantia nigra, striatum and hippocampus of rats. Life Sciences. 54: 375-9. PMID 8289599 DOI: 10.1016/0024-3205(94)00794-2  0.395
1994 Ayala A, Parrado J, Cano J, Machado A. Reduction of 1-methyl 1,2,3,4-tetrahydroisoquinoline level in substantia nigra of the aged rat Brain Research. 638: 334-336. PMID 8199872 DOI: 10.1016/0006-8993(94)90667-X  0.38
1994 Vizuete ML, Steffen V, Machado A, Cano J. 1-Methyl-4-phenylpyridinium has greater neurotoxic effect after selenium deficiency than after vitamin E deficiency in rat striatum. European Journal of Pharmacology. 270: 183-7. PMID 8039547 DOI: 10.1016/0926-6917(94)90061-2  0.389
1994 Santiago M, Machado A, Cano J. Effect of L-arginine/nitric oxide pathway on MPP+-induced cell injury in the striatum of rats British Journal of Pharmacology. 111: 837-842. PMID 8019760 DOI: 10.1111/J.1476-5381.1994.Tb14814.X  0.345
1993 Vizuete ML, Steffen V, Ayala A, Cano J, Machado A. Protective effect of deprenyl against 1-methyl-4-phenylpyridinium neurotoxicity in rat striatum. Neuroscience Letters. 152: 113-6. PMID 8515861 DOI: 10.1016/0304-3940(93)90496-8  0.324
1993 Castaño A, Cano J, Machado A. Low selenium diet affects monoamine turnover differentially in substantia nigra and striatum. Journal of Neurochemistry. 61: 1302-1307. PMID 8376988 DOI: 10.1111/J.1471-4159.1993.Tb13622.X  0.454
1993 Alvarez E, María CS, Machado A. Respiratory burst reaction changes with age in rat peritoneal macrophages Biochimica Et Biophysica Acta. 1179: 247-252. PMID 8218368 DOI: 10.1016/0167-4889(93)90079-5  0.337
1993 Santiago M, Machado A, Cano J. Regulation of prefrontal cortical dopamine release by dopamine receptor agonists and antagonists European Journal of Pharmacology. 239: 83-91. PMID 7901031 DOI: 10.1016/0014-2999(93)90979-R  0.362
1993 Santiago M, Machado A, Cano J. In vivo release of dopamine from rat striatum, substantia nigra and prefrontal cortex: Differential modulation by baclofen British Journal of Pharmacology. 109: 814-818. PMID 7689406 DOI: 10.1111/J.1476-5381.1993.Tb13647.X  0.39
1993 Santiago M, Machado A, Cano J. Effects of age and dopamine agonists and antagonists on striatal dopamine release in the rat: An in vivo microdialysis study Mechanisms of Ageing and Development. 67: 261-267. PMID 7686993 DOI: 10.1016/0047-6374(93)90004-B  0.321
1993 Castaño A, Herrera AJ, Cano J, Machado A. Effects of a short period of vitamin E-deficient diet in the turnover of different neurotransmitters in substantia nigra and striatum of the rat. Neuroscience. 53: 179-85. PMID 7682297 DOI: 10.1016/0306-4522(93)90296-R  0.304
1993 Castan˜o A, Vizuete ML, Cano J, Machado A. Turnover of monoamines in hippocampus of rats fed on vitamin E-deficient diet Brain Research. 604: 154-159. PMID 7681343 DOI: 10.1016/0006-8993(93)90362-Q  0.325
1993 Venero JL, Machado A, Cano J. Effect of ageing on monoamine turnover in the prefrontal cortex of rats Mechanisms of Ageing and Development. 72: 105-118. PMID 7512183 DOI: 10.1016/0047-6374(93)90093-7  0.429
1993 Santiago M, Machado A, Cano J. Regulation of the prefrontal cortical dopamine release by GABAA and GABAB receptor agonists and antagonists Brain Research. 630: 28-31. PMID 7509709 DOI: 10.1016/0006-8993(93)90638-4  0.345
1993 Venero JL, Roza Cdl, Machado A, Cano J. Age-related changes on monoamine turnover in hippocampus of rats Brain Research. 631: 89-96. PMID 7507792 DOI: 10.1016/0006-8993(93)91191-T  0.375
1992 Castaño A, Venero JL, Cano J, Machado A. Changes in the turnover of monoamines in prefrontal cortex of rats fed on vitamin E-deficient diet. Journal of Neurochemistry. 58: 1889-1895. PMID 1560242 DOI: 10.1111/J.1471-4159.1992.Tb10066.X  0.365
1992 Santiago M, Venero JL, Machado A, Cano J. In vivo protection of striatum from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists. Brain Research. 586: 203-207. PMID 1521154 DOI: 10.1016/0006-8993(92)91628-R  0.423
1992 Venero JL, Herrera AJ, Machado A, Cano J. Changes in neurotransmitter levels associated with the deficiency of some essential amino acids in the diet British Journal of Nutrition. 68: 409-420. PMID 1359904 DOI: 10.1079/Bjn19920098  0.379
1992 Santiago M, Machado A, Cano J. Fast sodium channel dependency of the somatodendritic release of dopamine in the rat's brain Neuroscience Letters. 148: 145-147. PMID 1338647 DOI: 10.1016/0304-3940(92)90825-R  0.371
1991 Machado A, Ayala A, Gordillo E, Revilla E, Maria CS. Relationship between enzymatic activity loss and post-translational protein modification in aging. Archives of Gerontology and Geriatrics. 12: 187-197. PMID 15374447 DOI: 10.1016/0167-4943(91)90027-N  0.328
1991 Venero JL, Machado A, Cano J. Determination of levels of biogenic amines and their metabolites and both forms of monoamine oxidase in prefrontal cortex of aged rats. Mechanisms of Ageing and Development. 56: 253-63. PMID 2089199 DOI: 10.1016/0047-6374(90)90086-U  0.314
1991 Ayala A, Gordillo E, Castaño A, Lobato M, Machado A. Involvement of diminution of glutathione, produced by deficiency of methionine in the diet, in the elevation of malic enzyme level in rat liver Biochimica Et Biophysica Acta. 1084: 48-52. PMID 2054376 DOI: 10.1016/0005-2760(91)90054-L  0.374
1991 Ayala A, Fabregat I, Machado A. The role of NADPH in the regulation of glucose-6-phosphate and 6-phosphogluconate dehydrogenases in rat adipose tissue. Molecular and Cellular Biochemistry. 105: 1-5. PMID 1922005 DOI: 10.1007/Bf00230368  0.365
1991 Gordillo E, Machado A. Implication of lysine residues in the loss of 6-phosphogluconate dehydrogenase activity in aging human erythrocytes. Mechanisms of Ageing and Development. 59: 291-297. PMID 1921518 DOI: 10.1016/0047-6374(91)90139-Q  0.333
1991 Steffen V, Gordillo E, Castaño A, Cano J, Machado A. Age-dependent changes in the activity and isoenzymatic pattern of the phosphofructokinase in different areas of the central nervous systems. Neuroscience Letters. 125: 15-8. PMID 1830378 DOI: 10.1016/0304-3940(91)90118-D  0.344
1991 Venero JL, Machado A, Cano J. Age effects on monoamine turnover of the rat substantia nigra Brain Research. 557: 109-114. PMID 1747745 DOI: 10.1016/0006-8993(91)90122-C  0.388
1991 Venero JL, Machado A, Cano J. Turnover of dopamine and serotonin and their metabolites in the striatum of aged rats. Journal of Neurochemistry. 56: 1940-1948. PMID 1709201 DOI: 10.1111/J.1471-4159.1991.Tb03451.X  0.39
1991 Vizuete ML, Santiago M, Herrera AJ, Venero JL, Machado A, Cano J. Effects of neonatal bilateral eye enucleation on postnatal development of the monoamines in posterior thalamus of the rat. Journal of Neural Transmission. 85: 231-242. PMID 1681825 DOI: 10.1007/Bf01244948  0.391
1990 Vizuete ML, Santiago M, Herrera AJ, Machado A, Cano J. Neonatal enucleation alters catecholamine and serotonin metabolism in the lateral geniculate and visual cortex in developing rats. Neurochemistry International. 17: 415-424. PMID 20504641 DOI: 10.1016/0197-0186(90)90023-M  0.317
1990 Ayala A, Fabregat I, Machado A. Possible involvement of NADPH requirement in regulation of Glucose-6-Phosphate and 6-Phosphogluconate dehydrogenase levels in rat liver Molecular and Cellular Biochemistry. 95: 107-115. PMID 2195319 DOI: 10.1007/Bf00219968  0.345
1990 Vizuete ML, Herrera AJ, Santiago M, Machado A, Cano J. Effects of enucleation on postnatal development of catecholamines and serotonin metabolism in the superior colliculus of the rat. Brain Research. 523: 281-287. PMID 1976025 DOI: 10.1016/0006-8993(90)91497-5  0.378
1989 Venero JL, Santiago M, Machado A, Cano J. Determination of monoamines and both forms of monoamine oxidase in the rat's substantia nigra during postnatal development. Life Sciences. 45: 1277-83. PMID 2811598 DOI: 10.1016/0024-3205(89)90130-6  0.343
1989 Villanueva C, Fabregat I, Machado A. Inhibition of fatty acid biosynthesis by bezafibrate in different rat cells. Biochemical Pharmacology. 38: 2505-2510. PMID 2757650 DOI: 10.1016/0006-2952(89)90095-6  0.338
1989 Maria CS, Revilla E, Fabregat I, Machado A. Hyperoxia and aging increase the guanylate cyclase activity of the rat lung Age. 12: 1-5. DOI: 10.1007/Bf02432511  0.353
1988 Maria CS, Machado A. Changes in some hepatic enzyme activities related to phase II drug metabolism in male and female rats as a function of age Mechanisms of Ageing and Development. 44: 115-125. PMID 3139940 DOI: 10.1016/0047-6374(88)90084-X  0.323
1987 Blanco P, Machado A, Satrústegui J. Variations due to hyperoxia and ageing in the activities of glutathione S-transferase and NADPH-cytochrome c reductase. Mechanisms of Ageing and Development. 39: 11-19. PMID 3613686 DOI: 10.1016/0047-6374(87)90082-0  0.369
1987 Fabregat I, Revilla E, Machado A. The NADPH consumption regulates the NADPH-producing pathways (pentose phosphate cycle and malic enzyme) in rat adipocytes. Molecular and Cellular Biochemistry. 74: 77-81. PMID 3587232 DOI: 10.1007/Bf00221914  0.326
1987 Ayala A, Machado A. Measurement ex-vivo of the inhibition of fatty acid biosynthesis by bezafibrate administration in different rat tissues Journal of Pharmacy and Pharmacology. 39: 551-552. PMID 2886626 DOI: 10.1111/J.2042-7158.1987.Tb03176.X  0.302
1986 Satrústegui J, Cuezva JM, Machado A. Increased basal gluconeogenesis in the aged rat Febs Letters. 197: 159-163. PMID 3512300 DOI: 10.1016/0014-5793(86)80318-0  0.349
1986 Maria CS, Machado A. Age and sex related differences in some rat renal NADPH-consuming detoxification enzymes Archives of Gerontology and Geriatrics. 5: 235-247. PMID 3099664 DOI: 10.1016/0167-4943(86)90025-7  0.356
1986 Ayala A, F-Lobato M, Machado A. Malic enzyme levels are increased by the activation of NADPH-consuming pathways: detoxification processes Febs Letters. 202: 102-106. PMID 3087771 DOI: 10.1016/0014-5793(86)80657-3  0.332
1985 Velez M, Machado A, Satrústegui J. Age-dependent modifications of rat heart succinate dehydrogenase Mechanisms of Ageing and Development. 32: 131-140. PMID 4087940 DOI: 10.1016/0047-6374(85)90076-4  0.362
1985 Fabregat I, Vitorica J, Satrustegui J, Machado A. The pentose phosphate cycle is regulated by NADPHNADP ratio in rat liver Archives of Biochemistry and Biophysics. 236: 110-118. PMID 3966788 DOI: 10.1016/0003-9861(85)90610-1  0.32
1985 Vitorica J, Clark A, Machado A, Satrústegui J. Impairment of glutamate uptake and absence of alterations in the energy-transducing ability of old rat brain mitochondria. Mechanisms of Ageing and Development. 29: 255-266. PMID 2985886 DOI: 10.1016/0047-6374(85)90066-1  0.329
1984 Fabregat I, Satrústegui J, Machado A. Interaction with protein SH groups could be involved in adriamycin cardiotoxicity Biochemical Medicine. 32: 289-295. PMID 6240263 DOI: 10.1016/0006-2944(84)90033-4  0.302
1984 Andrés A, Satrústegui J, Machado A. Development of enzymes of energy metabolism in rat heart. Neonatology. 45: 78-85. PMID 6230112 DOI: 10.1159/000241780  0.34
1983 Andrés A, Satrústegui J, Machado A. Development of NADPH-Consuming Pathways in Heart, Brain and Liver of the Rat Neonatology. 43: 198-204. PMID 6407538 DOI: 10.1159/000241629  0.327
1983 Satrustegui J, Bautista J, Machado A. NADPH/NADP+ ratio: regulatory implications in yeast glyoxylic acid cycle Molecular and Cellular Biochemistry. 51: 123-127. PMID 6343836 DOI: 10.1007/Bf00230397  0.309
1982 Cano J, Machado A, Roza C, Rodriguez-Echandia E. Effect of testosterone on serotonin and noradrenaline concentrations and taste bud cell number of rat circumvallate papilla Chemical Senses. 7: 109-116. DOI: 10.1093/Chemse/7.2.109  0.325
1981 Vitorica J, Cano J, Satrústegui J, Machado A. Comparison between developmental and senescent changes in enzyme activities linked to energy metabolism in rat heart. Mechanisms of Ageing and Development. 16: 105-116. PMID 7266074 DOI: 10.1016/0047-6374(81)90087-7  0.332
1980 Andrés A, Satrústegui J, Machado A. Development of NADPH-producing pathways in rat heart Biochemical Journal. 186: 799-803. PMID 7396838 DOI: 10.1042/Bj1860799  0.303
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