| Year |
Citation |
Score |
| 2023 |
Taddei RN, Perbet R, Mate de Gerando A, Wiedmer AE, Sanchez-Mico M, Connors Stewart T, Gaona A, Melloni A, Amaral AC, Duff K, Frosch MP, Gómez-Isla T. Tau Oligomer-Containing Synapse Elimination by Microglia and Astrocytes in Alzheimer Disease. Jama Neurology. 80: 1209-1221. PMID 37812432 DOI: 10.1001/jamaneurol.2023.3530 |
0.351 |
|
| 2023 |
Karakatsani ME, Ji R, Murillo MF, Kugelman T, Kwon N, Lao YH, Liu K, Pouliopoulos AN, Honig LS, Duff KE, Konofagou EE. Focused ultrasound mitigates pathology and improves spatial memory in Alzheimer's mice and patients. Theranostics. 13: 4102-4120. PMID 37554284 DOI: 10.7150/thno.79898 |
0.41 |
|
| 2023 |
Langworth-Green C, Patel S, Jaunmuktane Z, Jabbari E, Morris H, Thom M, Lees A, Hardy J, Zandi M, Duff K. Chronic effects of inflammation on tauopathies. The Lancet. Neurology. 22: 430-442. PMID 37059510 DOI: 10.1016/S1474-4422(23)00038-8 |
0.465 |
|
| 2022 |
Chen S, Chang Y, Li L, Acosta D, Li Y, Guo Q, Wang C, Turkes E, Morrison C, Julian D, Hester ME, Scharre DW, Santiskulvong C, Song SX, Plummer JT, ... ... Duff KE, et al. Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer's disease. Acta Neuropathologica Communications. 10: 188. PMID 36544231 DOI: 10.1186/s40478-022-01494-6 |
0.341 |
|
| 2022 |
Chen S, Acosta D, Li L, Liang J, Chang Y, Wang C, Fitzgerald J, Morrison C, Goulbourne CN, Nakano Y, Villegas NCH, Venkataraman L, Brown C, Serrano GE, Bell E, ... ... Duff KE, et al. Wolframin is a novel regulator of tau pathology and neurodegeneration. Acta Neuropathologica. PMID 35389045 DOI: 10.1007/s00401-022-02417-4 |
0.391 |
|
| 2022 |
Miranda AM, Ashok A, Chan RB, Zhou B, Xu Y, McIntire LB, Area-Gomez E, Di Paolo G, Duff KE, Oliveira TG, Nuriel T. Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice. Translational Psychiatry. 12: 129. PMID 35351864 DOI: 10.1038/s41398-022-01881-6 |
0.773 |
|
| 2021 |
Blaudin de Thé FX, Lassus B, Schaler AW, Fowler SL, Goulbourne CN, Jeggo R, Mannoury la Cour C, Millan MJ, Duff KE. P62 accumulates through neuroanatomical circuits in response to tauopathy propagation. Acta Neuropathologica Communications. 9: 177. PMID 34727983 DOI: 10.1186/s40478-021-01280-w |
0.383 |
|
| 2021 |
Meisl G, Hidari E, Allinson K, Rittman T, DeVos SL, Sanchez JS, Xu CK, Duff KE, Johnson KA, Rowe JB, Hyman BT, Knowles TPJ, Klenerman D. In vivo rate-determining steps of tau seed accumulation in Alzheimer's disease. Science Advances. 7: eabh1448. PMID 34714685 DOI: 10.1126/sciadv.abh1448 |
0.316 |
|
| 2021 |
Schaler AW, Runyan AM, Clelland CL, Sydney EJ, Fowler SL, Figueroa HY, Shioda S, Santa-Maria I, Duff KE, Myeku N. PAC1 receptor-mediated clearance of tau in postsynaptic compartments attenuates tau pathology in mouse brain. Science Translational Medicine. 13. PMID 34039738 DOI: 10.1126/scitranslmed.aba7394 |
0.818 |
|
| 2020 |
Fung CW, Guo J, Fu H, Figueroa HY, Konofagou EE, Duff KE. Atrophy associated with tau pathology precedes overt cell death in a mouse model of progressive tauopathy. Science Advances. 6. PMID 33067235 DOI: 10.1126/sciadv.abc8098 |
0.33 |
|
| 2020 |
Rodriguez GA, Barrett GM, Duff KE, Hussaini SA. Chemogenetic attenuation of neuronal activity in the entorhinal cortex reduces Aβ and tau pathology in the hippocampus. Plos Biology. 18: e3000851. PMID 32822389 DOI: 10.1371/Journal.Pbio.3000851 |
0.715 |
|
| 2020 |
Area-Gomez E, Larrea D, Pera M, Agrawal RR, Guilfoyle DN, Pirhaji L, Shannon K, Arain HA, Ashok A, Chen Q, Dillman AA, Figueroa HY, Cookson MR, Gross SS, Fraenkel E, ... Duff KE, et al. APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice. Scientific Reports. 10: 4277. PMID 32152337 DOI: 10.1038/S41598-020-61142-8 |
0.823 |
|
| 2019 |
Karakatsani ME, Kugelman T, Ji R, Murillo M, Wang S, Niimi Y, Small SA, Duff KE, Konofagou EE. Unilateral Focused Ultrasound-Induced Blood-Brain Barrier Opening Reduces Phosphorylated Tau from The rTg4510 Mouse Model. Theranostics. 9: 5396-5411. PMID 31410223 DOI: 10.7150/Thno.28717 |
0.41 |
|
| 2019 |
Fu H, Possenti A, Freer R, Nakano Y, Villegas NCH, Tang M, Cauhy PVM, Lassus BA, Chen S, Fowler SL, Figueroa HY, Huey ED, Johnson GVW, Vendruscolo M, Duff KE. A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology. Nature Neuroscience. 22: 47-56. PMID 30559469 DOI: 10.1038/S41593-018-0298-7 |
0.32 |
|
| 2019 |
Arain HA, Figueroa HY, Area-Gomez E, Duff KE, Nuriel T. P3-175: APOE4
INDUCES REGION-SPECIFIC DYSFUNCTION IN THE ENTORHINAL CORTEX OF AGED APOE4
MICE Alzheimer's & Dementia. 15: P997-P997. DOI: 10.1016/J.Jalz.2019.06.3204 |
0.709 |
|
| 2018 |
Fu H, Hardy J, Duff KE. Selective vulnerability in neurodegenerative diseases. Nature Neuroscience. PMID 30250262 DOI: 10.1038/S41593-018-0221-2 |
0.378 |
|
| 2017 |
Nuriel T, Peng KY, Ashok A, Dillman AA, Figueroa HY, Apuzzo J, Ambat J, Levy E, Cookson MR, Mathews PM, Duff KE. The Endosomal-Lysosomal Pathway Is Dysregulated by APOE4 Expression in Vivo. Frontiers in Neuroscience. 11: 702. PMID 29311783 DOI: 10.3389/Fnins.2017.00702 |
0.805 |
|
| 2017 |
Myeku N, Duff KE. Targeting the 26S Proteasome To Protect Against Proteotoxic Diseases. Trends in Molecular Medicine. PMID 29233753 DOI: 10.1016/j.molmed.2017.11.006 |
0.763 |
|
| 2017 |
Nuriel T, Angulo SL, Khan U, Ashok A, Chen Q, Figueroa HY, Emrani S, Liu L, Herman M, Barrett G, Savage V, Buitrago L, Cepeda-Prado E, Fung C, Goldberg E, ... ... Duff KE, et al. Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer's disease-like pathology. Nature Communications. 8: 1464. PMID 29133888 DOI: 10.1038/S41467-017-01444-0 |
0.806 |
|
| 2017 |
Kim J, Choi IY, Duff KE, Lee P. Progressive Pathological Changes in Neurochemical Profile of the Hippocampus and Early Changes in the Olfactory Bulbs of Tau Transgenic Mice (rTg4510). Neurochemical Research. PMID 28523532 DOI: 10.1007/S11064-017-2298-5 |
0.332 |
|
| 2017 |
Fu H, Rodriguez GA, Herman M, Emrani S, Nahmani E, Barrett G, Figueroa HY, Goldberg E, Hussaini SA, Duff KE. Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer's Disease. Neuron. PMID 28111080 DOI: 10.1016/J.Neuron.2016.12.023 |
0.682 |
|
| 2017 |
Nuriel T, Khan U, Angulo S, Ashok A, Gross SS, Hussaini SA, Moreno H, Small SA, Duff KE. APOE4 INDUCES ENTORHINAL CORTEX HYPERMETABOLISM IN THE ABSENCE OF OVERT ALZHEIMER’S DISEASE PATHOLOGY Alzheimer's & Dementia. 13: P204. DOI: 10.1016/J.Jalz.2017.07.070 |
0.765 |
|
| 2016 |
Fu H, Hussaini SA, Wegmann S, Profaci C, Daniels JD, Herman M, Emrani S, Figueroa HY, Hyman BT, Davies P, Duff KE. 3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Aged Tau Transgenic Mice. Plos One. 11: e0159463. PMID 27466814 DOI: 10.1371/Journal.Pone.0159463 |
0.393 |
|
| 2016 |
Wu JW, Hussaini SA, Bastille IM, Rodriguez GA, Mrejeru A, Rilett K, Sanders DW, Cook C, Fu H, Boonen RA, Herman M, Nahmani E, Emrani S, Figueroa YH, Diamond MI, ... ... Duff KE, et al. Neuronal activity enhances tau propagation and tau pathology in vivo. Nature Neuroscience. PMID 27322420 DOI: 10.1038/Nn.4328 |
0.788 |
|
| 2016 |
Fá M, Puzzo D, Piacentini R, Staniszewski A, Zhang H, Baltrons MA, Li Puma DD, Chatterjee I, Li J, Saeed F, Berman HL, Ripoli C, Gulisano W, Gonzalez J, Tian H, ... ... Duff KE, et al. Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory. Scientific Reports. 6: 19393. PMID 26786552 DOI: 10.1038/Srep19393 |
0.576 |
|
| 2015 |
Myeku N, Clelland CL, Emrani S, Kukushkin NV, Yu WH, Goldberg AL, Duff KE. Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling. Nature Medicine. PMID 26692334 DOI: 10.1038/nm.4011 |
0.816 |
|
| 2015 |
Konofagou E, Chen H, Olumolade O, Duff K. Neurotrophic delivery in Alzheimer’s-model mice Journal of Therapeutic Ultrasound. 3: O18. DOI: 10.1186/2050-5736-3-S1-O18 |
0.389 |
|
| 2014 |
Hussaini SA, Duff K. P2-098: FUNCTION AND DYSFUNCTION OF NEURONS IN THE ENTORHINAL CORTEX-HIPPOCAMPAL CIRCUIT IN MODELS OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P507-P507. DOI: 10.1016/J.Jalz.2014.05.772 |
0.373 |
|
| 2013 |
Yuan A, Kumar A, Sasaki T, Duff K, Nixon RA. Global axonal transport rates are unaltered in htau mice in vivo. Journal of Alzheimer's Disease : Jad. 37: 579-86. PMID 23948900 DOI: 10.3233/Jad-130671 |
0.364 |
|
| 2013 |
Walker LC, Diamond MI, Duff KE, Hyman BT. Mechanisms of protein seeding in neurodegenerative diseases. Jama Neurology. 70: 304-10. PMID 23599928 DOI: 10.1001/Jamaneurol.2013.1453 |
0.322 |
|
| 2013 |
Wu JW, Herman M, Liu L, Simoes S, Acker CM, Figueroa H, Steinberg JI, Margittai M, Kayed R, Zurzolo C, Di Paolo G, Duff KE. Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons. The Journal of Biological Chemistry. 288: 1856-70. PMID 23188818 DOI: 10.1074/Jbc.M112.394528 |
0.574 |
|
| 2013 |
Wu J, Dickstein D, Duff K. Mechanism of tau transfer: insights from cell culture and animal models Molecular Neurodegeneration. 8: P50. DOI: 10.1186/1750-1326-8-S1-P50 |
0.633 |
|
| 2013 |
Wolozin B, Vanderwyede T, Liu-Yesucevitz L, Dedeoglu A, Petrucelli L, Duff K. P4-034: Viewing neurodegeneration beyond the tangle: The role of RNA binding proteins in Alzheimer's disease Alzheimer's & Dementia. 9: P715-P716. DOI: 10.1016/J.Jalz.2013.05.1422 |
0.547 |
|
| 2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Duff K, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.731 |
|
| 2012 |
Vanderweyde T, Yu H, Varnum M, Liu-Yesucevitz L, Citro A, Ikezu T, Duff K, Wolozin B. Contrasting pathology of the stress granule proteins TIA-1 and G3BP in tauopathies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8270-83. PMID 22699908 DOI: 10.1523/Jneurosci.1592-12.2012 |
0.465 |
|
| 2012 |
Congdon EE, Wu JW, Myeku N, Figueroa YH, Herman M, Marinec PS, Gestwicki JE, Dickey CA, Yu WH, Duff KE. Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo. Autophagy. 8: 609-22. PMID 22361619 DOI: 10.4161/Auto.19048 |
0.824 |
|
| 2012 |
Liu L, Drouet V, Wu JW, Witter MP, Small SA, Clelland C, Duff K. Trans-synaptic spread of tau pathology in vivo. Plos One. 7: e31302. PMID 22312444 DOI: 10.1371/Journal.Pone.0031302 |
0.646 |
|
| 2012 |
Chan RB, Oliveira TG, Cortes EP, Honig LS, Duff KE, Small SA, Wenk MR, Shui G, Di Paolo G. Comparative lipidomic analysis of mouse and human brain with Alzheimer disease. The Journal of Biological Chemistry. 287: 2678-88. PMID 22134919 DOI: 10.1074/Jbc.M111.274142 |
0.348 |
|
| 2012 |
Wu J, Herman M, Duff K. Aggregation and size-dependent uptake and transport of tau aggregates in neurons Alzheimers & Dementia. 8: 97. DOI: 10.1016/J.Jalz.2012.05.241 |
0.574 |
|
| 2012 |
Myeku N, Yu WH, Duff K. O4-11-03: Interaction between the ubiquitin proteasome system, autophagy and progressive tauopathy in vivo Alzheimer's & Dementia. 8: P636-P637. DOI: 10.1016/J.Jalz.2012.05.1697 |
0.758 |
|
| 2011 |
Kim SR, Ries V, Cheng HC, Kareva T, Oo TF, Yu WH, Duff K, Kholodilov N, Burke RE. Age and α-synuclein expression interact to reveal a dependence of dopaminergic axons on endogenous Akt/PKB signaling. Neurobiology of Disease. 44: 215-22. PMID 21782946 DOI: 10.1016/J.Nbd.2011.07.003 |
0.531 |
|
| 2011 |
Loane DJ, Washington PM, Vardanian L, Pocivavsek A, Hoe HS, Duff KE, Cernak I, Rebeck GW, Faden AI, Burns MP. Modulation of ABCA1 by an LXR agonist reduces β-amyloid levels and improves outcome after traumatic brain injury. Journal of Neurotrauma. 28: 225-36. PMID 21175399 DOI: 10.1089/Neu.2010.1595 |
0.778 |
|
| 2011 |
Yu WH, Liu L, Robin C, Herman M, Figueroa H, Wenk M, Duff K. O4-03-01: Autophagic-lysosomal dysfunction in glucocerebrosidase-associated dementia with lewy bodies Alzheimer's & Dementia. 7: S686-S686. DOI: 10.1016/J.Jalz.2011.05.1980 |
0.503 |
|
| 2011 |
Wolozin B, Vanderwyede T, Liu-Yesucevitz L, McKee A, Duff K. O3-05-02: Stress granules and Alzheimer's disease: Colocalization with tau pathology Alzheimer's & Dementia. 7: S507-S507. DOI: 10.1016/J.Jalz.2011.05.1417 |
0.406 |
|
| 2010 |
Dall'Armi C, Hurtado-Lorenzo A, Tian H, Morel E, Nezu A, Chan RB, Yu WH, Robinson KS, Yeku O, Small SA, Duff K, Frohman MA, Wenk MR, Yamamoto A, Di Paolo G. The phospholipase D1 pathway modulates macroautophagy. Nature Communications. 1: 142. PMID 21266992 DOI: 10.1038/Ncomms1144 |
0.539 |
|
| 2010 |
Oliveira TG, Chan RB, Tian H, Laredo M, Shui G, Staniszewski A, Zhang H, Wang L, Kim TW, Duff KE, Wenk MR, Arancio O, Di Paolo G. Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16419-28. PMID 21147981 DOI: 10.1523/Jneurosci.3317-10.2010 |
0.325 |
|
| 2010 |
O'Leary JC, Li Q, Marinec P, Blair LJ, Congdon EE, Johnson AG, Jinwal UK, Koren J, Jones JR, Kraft C, Peters M, Abisambra JF, Duff KE, Weeber EJ, Gestwicki JE, et al. Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden. Molecular Neurodegeneration. 5: 45. PMID 21040568 DOI: 10.1186/1750-1326-5-45 |
0.368 |
|
| 2010 |
Netzer WJ, Powell C, Nong Y, Blundell J, Wong L, Duff K, Flajolet M, Greengard P. Lowering beta-amyloid levels rescues learning and memory in a Down syndrome mouse model. Plos One. 5: e10943. PMID 20532168 DOI: 10.1371/Journal.Pone.0010943 |
0.413 |
|
| 2010 |
Duff K, Kuret J, Congdon EE. Disaggregation of tau as a therapeutic approach to tauopathies. Current Alzheimer Research. 7: 235-40. PMID 20088807 DOI: 10.2174/156720510791050885 |
0.376 |
|
| 2010 |
Wray S, Devine M, Kunath T, Duff K, Morris HR, Houlden H, Rossor MN, Hardy J, Lewis PA. P1-111: Progress towards a neuronal cell model of the tauopathies Alzheimer's & Dementia. 6: S206-S207. DOI: 10.1016/J.Jalz.2010.05.660 |
0.553 |
|
| 2009 |
Area-Gomez E, de Groof AJ, Boldogh I, Bird TD, Gibson GE, Koehler CM, Yu WH, Duff KE, Yaffe MP, Pon LA, Schon EA. Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria. The American Journal of Pathology. 175: 1810-6. PMID 19834068 DOI: 10.2353/Ajpath.2009.090219 |
0.484 |
|
| 2009 |
Polydoro M, Acker CM, Duff K, Castillo PE, Davies P. Age-dependent impairment of cognitive and synaptic function in the htau mouse model of tau pathology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10741-9. PMID 19710325 DOI: 10.1523/Jneurosci.1065-09.2009 |
0.378 |
|
| 2009 |
Yu WH, Dorado B, Figueroa HY, Wang L, Planel E, Cookson MR, Clark LN, Duff KE. Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric alpha-synuclein. The American Journal of Pathology. 175: 736-47. PMID 19628769 DOI: 10.2353/Ajpath.2009.080928 |
0.629 |
|
| 2009 |
Congdon EE, Figueroa YH, Wang L, Toneva G, Chang E, Kuret J, Conrad C, Duff KE. Inhibition of tau polymerization with a cyanine dye in two distinct model systems. The Journal of Biological Chemistry. 284: 20830-9. PMID 19478088 DOI: 10.1074/Jbc.M109.016089 |
0.312 |
|
| 2009 |
Planel E, Bretteville A, Liu L, Virag L, Du AL, Yu WH, Dickson DW, Whittington RA, Duff KE. Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 2595-604. PMID 19279139 DOI: 10.1096/Fj.08-122424 |
0.599 |
|
| 2009 |
Kwan AC, Duff K, Gouras GK, Webb WW. Optical visualization of Alzheimer's pathology via multiphoton-excited intrinsic fluorescence and second harmonic generation. Optics Express. 17: 3679-89. PMID 19259208 DOI: 10.1364/Oe.17.003679 |
0.402 |
|
| 2009 |
Polydoro M, Acker CM, Duff K, Castillo PE, Davies P. O4-03-01: Age-dependent impairment of cognitive and synaptic function in transgenic mouse model of tau pathology (htau mouse) Alzheimer's & Dementia. 5: P153-P154. DOI: 10.1016/J.Jalz.2009.05.531 |
0.34 |
|
| 2008 |
Liu L, Duff K. A technique for serial collection of cerebrospinal fluid from the cisterna magna in mouse. Journal of Visualized Experiments : Jove. PMID 19066529 DOI: 10.3791/960 |
0.511 |
|
| 2008 |
Small SA, Duff K. Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis. Neuron. 60: 534-42. PMID 19038212 DOI: 10.1016/J.Neuron.2008.11.007 |
0.492 |
|
| 2008 |
Planel E, Krishnamurthy P, Miyasaka T, Liu L, Herman M, Kumar A, Bretteville A, Figueroa HY, Yu WH, Whittington RA, Davies P, Takashima A, Nixon RA, Duff KE. Anesthesia-induced hyperphosphorylation detaches 3-repeat tau from microtubules without affecting their stability in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12798-807. PMID 19036972 DOI: 10.1523/Jneurosci.4101-08.2008 |
0.561 |
|
| 2008 |
Congdon EE, Duff KE. Is tau aggregation toxic or protective? Journal of Alzheimer's Disease : Jad. 14: 453-7. PMID 18688098 |
0.351 |
|
| 2008 |
Trojanowski JQ, Duff K, Fillit H, Koroshetz W, Kuret J, Murphy D, Refolo L. New directions for frontotemporal dementia drug discovery. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 4: 89-93. PMID 18631953 DOI: 10.1016/J.Jalz.2007.06.001 |
0.318 |
|
| 2008 |
Liu L, Orozco IJ, Planel E, Wen Y, Bretteville A, Krishnamurthy P, Wang L, Herman M, Figueroa H, Yu WH, Arancio O, Duff K. A transgenic rat that develops Alzheimer's disease-like amyloid pathology, deficits in synaptic plasticity and cognitive impairment. Neurobiology of Disease. 31: 46-57. PMID 18504134 DOI: 10.1016/J.Nbd.2008.03.005 |
0.609 |
|
| 2008 |
Hirata-Fukae C, Li HF, Hoe HS, Gray AJ, Minami SS, Hamada K, Niikura T, Hua F, Tsukagoshi-Nagai H, Horikoshi-Sakuraba Y, Mughal M, Rebeck GW, LaFerla FM, Mattson MP, Iwata N, ... ... Duff KE, et al. Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model. Brain Research. 1216: 92-103. PMID 18486110 DOI: 10.1016/J.Brainres.2008.03.079 |
0.802 |
|
| 2008 |
Muhammad A, Flores I, Zhang H, Yu R, Staniszewski A, Planel E, Herman M, Ho L, Kreber R, Honig LS, Ganetzky B, Duff K, Arancio O, Small SA. Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation. Proceedings of the National Academy of Sciences of the United States of America. 105: 7327-32. PMID 18480253 DOI: 10.1073/Pnas.0802545105 |
0.505 |
|
| 2008 |
Wen Y, Yu WH, Maloney B, Bailey J, Ma J, Marié I, Maurin T, Wang L, Figueroa H, Herman M, Krishnamurthy P, Liu L, Planel E, Lau LF, Lahiri DK, ... Duff K, et al. Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing. Neuron. 57: 680-90. PMID 18341989 DOI: 10.1016/J.Neuron.2008.02.024 |
0.603 |
|
| 2008 |
Wen Y, Planel E, Herman M, Figueroa HY, Wang L, Liu L, Lau LF, Yu WH, Duff KE. Interplay between cyclin-dependent kinase 5 and glycogen synthase kinase 3 beta mediated by neuregulin signaling leads to differential effects on tau phosphorylation and amyloid precursor protein processing. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2624-32. PMID 18322105 DOI: 10.1523/Jneurosci.5245-07.2008 |
0.57 |
|
| 2008 |
Yuan A, Kumar A, Peterhoff C, Duff K, Nixon RA. Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1682-7. PMID 18272688 DOI: 10.1523/Jneurosci.5242-07.2008 |
0.339 |
|
| 2008 |
Yu WH, Matsuoka Y, Sziráki I, Hashim A, Lafrancois J, Sershen H, Duff KE. Increased dopaminergic neuron sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in transgenic mice expressing mutant A53T alpha-synuclein. Neurochemical Research. 33: 902-11. PMID 17999181 DOI: 10.1007/s11064-007-9533-4 |
0.722 |
|
| 2008 |
Small S, Duff K, Arancio O, Ganetzky B, Honig L. O3-01-03: Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.407 |
0.454 |
|
| 2007 |
Planel E, Tatebayashi Y, Miyasaka T, Liu L, Wang L, Herman M, Yu WH, Luchsinger JA, Wadzinski B, Duff KE, Takashima A. Insulin dysfunction induces in vivo tau hyperphosphorylation through distinct mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13635-48. PMID 18077675 DOI: 10.1523/Jneurosci.3949-07.2007 |
0.584 |
|
| 2007 |
Cole AR, Noble W, van Aalten L, Plattner F, Meimaridou R, Hogan D, Taylor M, LaFrancois J, Gunn-Moore F, Verkhratsky A, Oddo S, LaFerla F, Giese KP, Dineley KT, Duff K, et al. Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression. Journal of Neurochemistry. 103: 1132-44. PMID 17683481 DOI: 10.1111/J.1471-4159.2007.04829.X |
0.688 |
|
| 2007 |
Falangola MF, Dyakin VV, Lee SP, Bogart A, Babb JS, Duff K, Nixon R, Helpern JA. Quantitative MRI reveals aging-associated T2 changes in mouse models of Alzheimer's disease. Nmr in Biomedicine. 20: 343-51. PMID 17451178 DOI: 10.1002/Nbm.1163 |
0.501 |
|
| 2007 |
Planel E, Richter KE, Nolan CE, Finley JE, Liu L, Wen Y, Krishnamurthy P, Herman M, Wang L, Schachter JB, Nelson RB, Lau LF, Duff KE. Anesthesia leads to tau hyperphosphorylation through inhibition of phosphatase activity by hypothermia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3090-7. PMID 17376970 DOI: 10.1523/Jneurosci.4854-06.2007 |
0.371 |
|
| 2007 |
Gray AJ, Sakaguchi G, Shiratori C, Becker AG, LaFrancois J, Aisen PS, Duff K, Matsuoka Y. Antibody against C-terminal Abeta selectively elevates plasma Abeta. Neuroreport. 18: 293-6. PMID 17314674 DOI: 10.1097/Wnr.0B013E3280148E76 |
0.725 |
|
| 2007 |
Duff K, Krishnamurthy P, Planel E, Hutton M. Animal models of tauopathy Alzheimer's Disease: Advances in Genetics, Molecular and Cellular Biology. 215-236. DOI: 10.1007/978-0-387-35135-3_13 |
0.372 |
|
| 2006 |
Duff K. Normal and abnormal tau neurobiology. Alzheimer Disease and Associated Disorders. 20: 202-5. PMID 17132962 DOI: 10.1097/01.Wad.0000213881.01289.D9 |
0.358 |
|
| 2006 |
Burns MP, Igbavboa U, Wang L, Wood WG, Duff K. Cholesterol distribution, not total levels, correlate with altered amyloid precursor protein processing in statin-treated mice. Neuromolecular Medicine. 8: 319-28. PMID 16775383 DOI: 10.1385/Nmm:8:3:319 |
0.661 |
|
| 2006 |
Burns MP, Vardanian L, Pajoohesh-Ganji A, Wang L, Cooper M, Harris DC, Duff K, Rebeck GW. The effects of ABCA1 on cholesterol efflux and Abeta levels in vitro and in vivo. Journal of Neurochemistry. 98: 792-800. PMID 16771834 DOI: 10.1111/J.1471-4159.2006.03925.X |
0.747 |
|
| 2006 |
Bell KF, Ducatenzeiler A, Ribeiro-da-Silva A, Duff K, Bennett DA, Cuello AC. The amyloid pathology progresses in a neurotransmitter-specific manner. Neurobiology of Aging. 27: 1644-57. PMID 16271419 DOI: 10.1016/J.Neurobiolaging.2005.09.034 |
0.479 |
|
| 2006 |
Rodriguez GA, Hussaini SA, Duff KE. P1-022: ATTENUATION OF Aβ-ASSOCIATED HYPERACTIVITY IN THE ENTORHINAL CORTEX AMELIORATES HIPPOCAMPAL PLAQUE BURDEN Alzheimer's & Dementia. 14: P273-P273. DOI: 10.1016/J.Jalz.2018.06.023 |
0.634 |
|
| 2006 |
Burns MP, Cernak I, Vardanian L, Cruz MI, Cartagena C, Wang L, Duff K, Rebeck GW. O4-01-04: Traumatic brain injury-a model for cholesterol redistribution and A-beta metabolism Alzheimer's & Dementia. 2: S75-S75. DOI: 10.1016/J.Jalz.2006.05.294 |
0.691 |
|
| 2005 |
Soreghan BA, Lu BW, Thomas SN, Duff K, Rakhmatulin EA, Nikolskaya T, Chen T, Yang AJ. Using proteomics and network analysis to elucidate the consequences of synaptic protein oxidation in a PS1 + AbetaPP mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 8: 227-41. PMID 16340081 DOI: 10.3233/Jad-2005-8302 |
0.397 |
|
| 2005 |
Yu WH, Cuervo AM, Kumar A, Peterhoff CM, Schmidt SD, Lee JH, Mohan PS, Mercken M, Farmery MR, Tjernberg LO, Jiang Y, Duff K, Uchiyama Y, Näslund J, Mathews PM, et al. Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease. The Journal of Cell Biology. 171: 87-98. PMID 16203860 DOI: 10.1083/Jcb.200505082 |
0.643 |
|
| 2005 |
Duff K, Planel E. Untangling memory deficits. Nature Medicine. 11: 826-7. PMID 16079873 DOI: 10.1038/Nm0805-826 |
0.37 |
|
| 2005 |
Kumar-Singh S, Pirici D, McGowan E, Serneels S, Ceuterick C, Hardy J, Duff K, Dickson D, Van Broeckhoven C. Dense-core plaques in Tg2576 and PSAPP mouse models of Alzheimer's disease are centered on vessel walls. The American Journal of Pathology. 167: 527-43. PMID 16049337 DOI: 10.1016/S0002-9440(10)62995-1 |
0.72 |
|
| 2005 |
Matsuoka Y, Shao L, Debnath M, Lafrancois J, Becker A, Gray A, Aisen P, Mathis C, Klunk W, Duff K. An Abeta sequestration approach using non-antibody Abeta binding agents. Current Alzheimer Research. 2: 265-8. PMID 15974928 DOI: 10.2174/1567205053585774 |
0.73 |
|
| 2005 |
Andorfer C, Acker CM, Kress Y, Hof PR, Duff K, Davies P. Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5446-54. PMID 15930395 DOI: 10.1523/Jneurosci.4637-04.2005 |
0.462 |
|
| 2005 |
Falangola MF, Lee SP, Nixon RA, Duff K, Helpern JA. Histological co-localization of iron in Abeta plaques of PS/APP transgenic mice. Neurochemical Research. 30: 201-5. PMID 15895823 DOI: 10.1007/S11064-004-2442-X |
0.456 |
|
| 2005 |
Noble W, Planel E, Zehr C, Olm V, Meyerson J, Suleman F, Gaynor K, Wang L, LaFrancois J, Feinstein B, Burns M, Krishnamurthy P, Wen Y, Bhat R, Lewis J, ... ... Duff K, et al. Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 6990-5. PMID 15867159 DOI: 10.1073/Pnas.0500466102 |
0.751 |
|
| 2005 |
Falangola MF, Ardekani BA, Lee SP, Babb JS, Bogart A, Dyakin VV, Nixon R, Duff K, Helpern JA. Application of a non-linear image registration algorithm to quantitative analysis of T2 relaxation time in transgenic mouse models of AD pathology. Journal of Neuroscience Methods. 144: 91-7. PMID 15848243 DOI: 10.1016/J.Jneumeth.2004.10.012 |
0.372 |
|
| 2004 |
Tsai J, Grutzendler J, Duff K, Gan WB. Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches. Nature Neuroscience. 7: 1181-3. PMID 15475950 DOI: 10.1038/Nn1335 |
0.448 |
|
| 2004 |
Lee SP, Falangola MF, Nixon RA, Duff K, Helpern JA. Visualization of beta-amyloid plaques in a transgenic mouse model of Alzheimer's disease using MR microscopy without contrast reagents. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 52: 538-44. PMID 15334572 DOI: 10.1002/Mrm.20196 |
0.479 |
|
| 2004 |
Cataldo AM, Peterhoff CM, Schmidt SD, Terio NB, Duff K, Beard M, Mathews PM, Nixon RA. Presenilin mutations in familial Alzheimer disease and transgenic mouse models accelerate neuronal lysosomal pathology. Journal of Neuropathology and Experimental Neurology. 63: 821-30. PMID 15330337 DOI: 10.1093/Jnen/63.8.821 |
0.503 |
|
| 2004 |
Burns MP, Duff K. Brain on steroids resists neurodegeneration. Nature Medicine. 10: 675-6. PMID 15229510 DOI: 10.1038/Nm0704-675 |
0.64 |
|
| 2004 |
Kowa H, Sakakura T, Matsuura Y, Wakabayashi T, Mann DM, Duff K, Tsuji S, Hashimoto T, Iwatsubo T. Mostly separate distributions of CLAC- versus Abeta40- or thioflavin S-reactivities in senile plaques reveal two distinct subpopulations of beta-amyloid deposits. The American Journal of Pathology. 165: 273-81. PMID 15215182 DOI: 10.1016/S0002-9440(10)63295-6 |
0.462 |
|
| 2004 |
Echeverria V, Ducatenzeiler A, Alhonen L, Janne J, Grant SM, Wandosell F, Muro A, Baralle F, Li H, Duff K, Szyf M, Cuello AC. Rat transgenic models with a phenotype of intracellular Abeta accumulation in hippocampus and cortex. Journal of Alzheimer's Disease : Jad. 6: 209-19. PMID 15201476 DOI: 10.3233/Jad-2004-6301 |
0.368 |
|
| 2004 |
Sadowski M, Pankiewicz J, Scholtzova H, Ji Y, Quartermain D, Jensen CH, Duff K, Nixon RA, Gruen RJ, Wisniewski T. Amyloid-beta deposition is associated with decreased hippocampal glucose metabolism and spatial memory impairment in APP/PS1 mice. Journal of Neuropathology and Experimental Neurology. 63: 418-28. PMID 15198121 DOI: 10.1093/Jnen/63.5.418 |
0.442 |
|
| 2004 |
Horikoshi Y, Sakaguchi G, Becker AG, Gray AJ, Duff K, Aisen PS, Yamaguchi H, Maeda M, Kinoshita N, Matsuoka Y. Development of Abeta terminal end-specific antibodies and sensitive ELISA for Abeta variant. Biochemical and Biophysical Research Communications. 319: 733-7. PMID 15184044 DOI: 10.1016/J.Bbrc.2004.05.051 |
0.735 |
|
| 2004 |
Sadowski M, Pankiewicz J, Scholtzova H, Li YS, Quartermain D, Duff K, Wisniewski T. Links between the pathology of Alzheimer's disease and vascular dementia. Neurochemical Research. 29: 1257-66. PMID 15176482 DOI: 10.1023/B:Nere.0000023612.66691.E6 |
0.468 |
|
| 2004 |
Duff K, Suleman F. Transgenic mouse models of Alzheimer's disease: how useful have they been for therapeutic development? Briefings in Functional Genomics & Proteomics. 3: 47-59. PMID 15163359 DOI: 10.1093/Bfgp/3.1.47 |
0.426 |
|
| 2004 |
Saura CA, Choi SY, Beglopoulos V, Malkani S, Zhang D, Shankaranarayana Rao BS, Chattarji S, Kelleher RJ, Kandel ER, Duff K, Kirkwood A, Shen J. Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration. Neuron. 42: 23-36. PMID 15066262 DOI: 10.1016/S0896-6273(04)00182-5 |
0.347 |
|
| 2004 |
Helpern JA, Lee SP, Falangola MF, Dyakin VV, Bogart A, Ardekani B, Duff K, Branch C, Wisniewski T, de Leon MJ, Wolf O, O'Shea J, Nixon RA. MRI assessment of neuropathology in a transgenic mouse model of Alzheimer's disease. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 51: 794-8. PMID 15065253 DOI: 10.1002/Mrm.20038 |
0.514 |
|
| 2004 |
Klein RL, Lin WL, Dickson DW, Lewis J, Hutton M, Duff K, Meyer EM, King MA. Rapid neurofibrillary tangle formation after localized gene transfer of mutated tau. The American Journal of Pathology. 164: 347-53. PMID 14695347 DOI: 10.1016/S0002-9440(10)63124-0 |
0.615 |
|
| 2004 |
Yang D, Kumar A, Peterson J, Peterhoff CM, Duff K, Nixon RA, Jeyathevan R, Martins RN, Cataldo AM. P3-289 Neurodegeneration in a mouse model of Alzheimer's disease (AD): roles of apoptosis and autophagy Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81439-8 |
0.441 |
|
| 2004 |
Andorfer CA, Acker CM, Kress Y, Duff K, Davies P. P2-078 Neurofibrillary tangles and cell death in transgenic mice expressing non-mutant human isoforms of TAU Neurobiology of Aging. 25: S246. DOI: 10.1016/S0197-4580(04)80825-X |
0.394 |
|
| 2004 |
Scholtzova H, Pankiewicz J, Sadowski M, Quartermain D, Jensen CH, Duff K, Nixon RA, Helpern JH, Gruen RJ, Wisniewski T. P2-007 Age-associated behavioral, metabolic, and structural changes in wild-type littermates of Alzheimer's transgenic mice Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80755-3 |
0.366 |
|
| 2004 |
Bell KF, Ribeiro-da-Silva A, Duff K, Cuello AC. P1-258 A sequential and neurotransmitter-specific involvement of dystrophic neurites in the amyloid pathology Neurobiology of Aging. 25: S169. DOI: 10.1016/S0197-4580(04)80571-2 |
0.406 |
|
| 2004 |
Nixon RA, Yu WH, Cuervo AM, Cataldo AM, Mathews PM, Yang D, Zheng P, Peterhoff CM, Kumar A, Jiang Y, Peterson J, Schmidt SD, Mohan P, Duff K, Hassinger L, et al. S4-03-04 Autophagy in Alzheimer's disease pathogenesis Neurobiology of Aging. 25: S70-S71. DOI: 10.1016/S0197-4580(04)80240-9 |
0.578 |
|
| 2004 |
Duff K, Noble W. S3-01-01 Symposia session Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80151-9 |
0.5 |
|
| 2004 |
Planel E, Sahara N, Tatebayashi Y, Launey T, Ishiguro K, Duff K, Takashima A. O2-05-07 Insulin dysfunction induces abnormal tau hyperphosphorylation through two distinct mechanisms: implications for diabetes and Alzheimer's disease Neurobiology of Aging. 25: S42-S43. DOI: 10.1016/S0197-4580(04)80141-6 |
0.363 |
|
| 2003 |
Petanceska SS, DeRosa S, Sharma A, Diaz N, Duff K, Tint SG, Refolo LM, Pappolla M. Changes in apolipoprotein E expression in response to dietary and pharmacological modulation of cholesterol. Journal of Molecular Neuroscience : Mn. 20: 395-406. PMID 14501024 DOI: 10.1385/Jmn:20:3:395 |
0.427 |
|
| 2003 |
Kurt MA, Davies DC, Kidd M, Duff K, Howlett DR. Hyperphosphorylated tau and paired helical filament-like structures in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes. Neurobiology of Disease. 14: 89-97. PMID 13678670 DOI: 10.1016/S0969-9961(03)00084-6 |
0.528 |
|
| 2003 |
Lemere CA, Spooner ET, LaFrancois J, Malester B, Mori C, Leverone JF, Matsuoka Y, Taylor JW, DeMattos RB, Holtzman DM, Clements JD, Selkoe DJ, Duff KE. Evidence for peripheral clearance of cerebral Abeta protein following chronic, active Abeta immunization in PSAPP mice. Neurobiology of Disease. 14: 10-8. PMID 13678662 DOI: 10.1016/S0969-9961(03)00044-5 |
0.713 |
|
| 2003 |
Wadghiri YZ, Sigurdsson EM, Sadowski M, Elliott JI, Li Y, Scholtzova H, Tang CY, Aguinaldo G, Pappolla M, Duff K, Wisniewski T, Turnbull DH. Detection of Alzheimer's amyloid in transgenic mice using magnetic resonance microimaging. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 50: 293-302. PMID 12876705 DOI: 10.1002/Mrm.10529 |
0.477 |
|
| 2003 |
Andorfer C, Kress Y, Espinoza M, de Silva R, Tucker KL, Barde YA, Duff K, Davies P. Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms. Journal of Neurochemistry. 86: 582-90. PMID 12859672 DOI: 10.1046/J.1471-4159.2003.01879.X |
0.521 |
|
| 2003 |
Burns M, Gaynor K, Olm V, Mercken M, LaFrancois J, Wang L, Mathews PM, Noble W, Matsuoka Y, Duff K. Presenilin redistribution associated with aberrant cholesterol transport enhances beta-amyloid production in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5645-9. PMID 12843267 |
0.82 |
|
| 2003 |
Noble W, Olm V, Takata K, Casey E, Mary O, Meyerson J, Gaynor K, LaFrancois J, Wang L, Kondo T, Davies P, Burns M, Veeranna, Nixon R, Dickson D, ... ... Duff K, et al. Cdk5 is a key factor in tau aggregation and tangle formation in vivo. Neuron. 38: 555-65. PMID 12765608 DOI: 10.1016/S0896-6273(03)00259-9 |
0.825 |
|
| 2003 |
Burns M, Duff K. Use of in vivo models to study the role of cholesterol in the etiology of Alzheimer's disease. Neurochemical Research. 28: 979-86. PMID 12737522 DOI: 10.1023/A:1023294820218 |
0.701 |
|
| 2003 |
Baslow MH, Suckow RF, Gaynor K, Bhakoo KK, Marks N, Saito M, Saito M, Duff K, Matsuoka Y, Berg MJ. Brain damage results in down-regulation of N-acetylaspartate as a neuronal osmolyte. Neuromolecular Medicine. 3: 95-104. PMID 12728192 DOI: 10.1385/Nmm:3:2:95 |
0.687 |
|
| 2003 |
Burns MP, Noble WJ, Olm V, Gaynor K, Casey E, LaFrancois J, Wang L, Duff K. Co-localization of cholesterol, apolipoprotein E and fibrillar Abeta in amyloid plaques. Brain Research. Molecular Brain Research. 110: 119-25. PMID 12573540 DOI: 10.1016/S0169-328X(02)00647-2 |
0.746 |
|
| 2003 |
Matsuoka Y, Saito M, LaFrancois J, Saito M, Gaynor K, Olm V, Wang L, Casey E, Lu Y, Shiratori C, Lemere C, Duff K. Novel therapeutic approach for the treatment of Alzheimer's disease by peripheral administration of agents with an affinity to beta-amyloid. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 29-33. PMID 12514198 DOI: 10.1523/Jneurosci.23-01-00029.2003 |
0.744 |
|
| 2002 |
Duff K, Noble W, Gaynor K, Matsuoka Y. Organotypic slice cultures from transgenic mice as disease model systems. Journal of Molecular Neuroscience : Mn. 19: 317-20. PMID 12540058 DOI: 10.1385/Jmn:19:3:317 |
0.792 |
|
| 2002 |
Burns M, Duff K. Cholesterol in Alzheimer's disease and tauopathy. Annals of the New York Academy of Sciences. 977: 367-75. PMID 12480774 DOI: 10.1111/J.1749-6632.2002.Tb04839.X |
0.719 |
|
| 2002 |
Urbanc B, Cruz L, Le R, Sanders J, Ashe KH, Duff K, Stanley HE, Irizarry MC, Hyman BT. Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 99: 13990-5. PMID 12374847 DOI: 10.1073/Pnas.222433299 |
0.504 |
|
| 2002 |
Petanceska SS, DeRosa S, Olm V, Diaz N, Sharma A, Thomas-Bryant T, Duff K, Pappolla M, Refolo LM. Statin therapy for Alzheimer's disease: will it work? Journal of Molecular Neuroscience : Mn. 19: 155-61. PMID 12212773 DOI: 10.1007/S12031-002-0026-2 |
0.47 |
|
| 2002 |
Lee HJ, Zhang Y, Zhu C, Duff K, Pardridge WM. Imaging brain amyloid of Alzheimer disease in vivo in transgenic mice with an Abeta peptide radiopharmaceutical. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 223-31. PMID 11823720 DOI: 10.1097/00004647-200202000-00010 |
0.44 |
|
| 2002 |
Zheng H, Xu H, Uljon SN, Gross R, Hardy K, Gaynor J, Lafrancois J, Simpkins J, Refolo LM, Petanceska S, Wang R, Duff K. Modulation of A(beta) peptides by estrogen in mouse models. Journal of Neurochemistry. 80: 191-6. PMID 11796757 DOI: 10.1046/J.0022-3042.2001.00690.X |
0.423 |
|
| 2001 |
Refolo LM, Pappolla MA, LaFrancois J, Malester B, Schmidt SD, Thomas-Bryant T, Tint GS, Wang R, Mercken M, Petanceska SS, Duff KE. A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease. Neurobiology of Disease. 8: 890-9. PMID 11592856 DOI: 10.1006/nbdi.2001.0422 |
0.379 |
|
| 2001 |
Kurt MA, Davies DC, Kidd M, Duff K, Rolph SC, Jennings KH, Howlett DR. Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes. Experimental Neurology. 171: 59-71. PMID 11520121 DOI: 10.1006/exnr.2001.7717 |
0.392 |
|
| 2001 |
Poduslo JF, Curran GL, Wengenack TM, Malester B, Duff K. Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease. Neurobiology of Disease. 8: 555-67. PMID 11493021 DOI: 10.1006/Nbdi.2001.0402 |
0.405 |
|
| 2001 |
Le R, Cruz L, Urbanc B, Knowles RB, Hsiao-Ashe K, Duff K, Irizarry MC, Stanley HE, Hyman BT. Plaque-induced abnormalities in neurite geometry in transgenic models of Alzheimer disease: implications for neural system disruption. Journal of Neuropathology and Experimental Neurology. 60: 753-8. PMID 11487049 DOI: 10.1093/Jnen/60.8.753 |
0.498 |
|
| 2001 |
Duff K, Rao MV. Progress in the modeling of neurodegenerative diseases in transgenic mice. Current Opinion in Neurology. 14: 441-7. PMID 11470959 DOI: 10.1097/00019052-200108000-00003 |
0.43 |
|
| 2001 |
Duff K. Transgenic mouse models of Alzheimer's disease: phenotype and mechanisms of pathogenesis. Biochemical Society Symposium. 195-202. PMID 11447835 DOI: 10.1042/Bst028A018B |
0.493 |
|
| 2001 |
Matsuoka Y, Vila M, Lincoln S, McCormack A, Picciano M, LaFrancois J, Yu X, Dickson D, Langston WJ, McGowan E, Farrer M, Hardy J, Duff K, Przedborski S, Di Monte DA. Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter. Neurobiology of Disease. 8: 535-9. PMID 11442360 DOI: 10.1006/Nbdi.2001.0392 |
0.692 |
|
| 2001 |
Matsuoka Y, Picciano M, La Francois J, Duff K. Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease. Neuroscience. 104: 609-13. PMID 11440793 DOI: 10.1016/S0306-4522(01)00115-4 |
0.353 |
|
| 2001 |
Hernandez D, Sugaya K, Qu T, McGowan E, Duff K, McKinney M. Survival and plasticity of basal forebrain cholinergic systems in mice transgenic for presenilin-1 and amyloid precursor protein mutant genes. Neuroreport. 12: 1377-84. PMID 11388415 DOI: 10.1097/00001756-200105250-00018 |
0.647 |
|
| 2001 |
Matsuoka Y, Picciano M, Malester B, LaFrancois J, Zehr C, Daeschner JM, Olschowka JA, Fonseca MI, O'Banion MK, Tenner AJ, Lemere CA, Duff K. Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease. The American Journal of Pathology. 158: 1345-54. PMID 11290552 DOI: 10.1016/S0002-9440(10)64085-0 |
0.483 |
|
| 2001 |
Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, Hardy J, Duff K, Jantzen P, DiCarlo G, Wilcock D, Connor K, Hatcher J, Hope C, Gordon M, Arendash GW. Erratum: correction: Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease Nature. 412: 660-660. DOI: 10.1038/35088102 |
0.469 |
|
| 2000 |
Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, Hardy J, Duff K, Jantzen P, DiCarlo G, Wilcock D, Connor K, Hatcher J, Hope C, Gordon M, Arendash GW. A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature. 408: 982-5. PMID 11140686 DOI: 10.1038/35050116 |
0.513 |
|
| 2000 |
Wengenack TM, Whelan S, Curran GL, Duff KE, Poduslo JF. Quantitative histological analysis of amyloid deposition in Alzheimer's double transgenic mouse brain. Neuroscience. 101: 939-44. PMID 11113343 |
0.402 |
|
| 2000 |
Refolo LM, Malester B, LaFrancois J, Bryant-Thomas T, Wang R, Tint GS, Sambamurti K, Duff K, Pappolla MA. Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model. Neurobiology of Disease. 7: 321-31. PMID 10964604 DOI: 10.1006/Nbdi.2000.0304 |
0.481 |
|
| 2000 |
Gandy S, Duff K. Post-menopausal estrogen deprivation and Alzheimer's disease. Experimental Gerontology. 35: 503-11. PMID 10959038 DOI: 10.1016/S0531-5565(00)00116-9 |
0.473 |
|
| 2000 |
Lewis J, McGowan E, Rockwood J, Melrose H, Nacharaju P, Van Slegtenhorst M, Gwinn-Hardy K, Paul Murphy M, Baker M, Yu X, Duff K, Hardy J, Corral A, Lin WL, Yen SH, et al. Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein. Nature Genetics. 25: 402-5. PMID 10932182 DOI: 10.1038/78078 |
0.743 |
|
| 2000 |
Takeuchi A, Irizarry MC, Duff K, Saido TC, Hsiao Ashe K, Hasegawa M, Mann DM, Hyman BT, Iwatsubo T. Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss. The American Journal of Pathology. 157: 331-9. PMID 10880403 DOI: 10.1016/S0002-9440(10)64544-0 |
0.465 |
|
| 2000 |
Barrow PA, Empson RM, Gladwell SJ, Anderson CM, Killick R, Yu X, Jefferys JG, Duff K. Functional phenotype in transgenic mice expressing mutant human presenilin-1. Neurobiology of Disease. 7: 119-26. PMID 10783295 DOI: 10.1006/Nbdi.1999.0276 |
0.374 |
|
| 2000 |
Duff K, Knight H, Refolo LM, Sanders S, Yu X, Picciano M, Malester B, Hutton M, Adamson J, Goedert M, Burki K, Davies P. Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes. Neurobiology of Disease. 7: 87-98. PMID 10783293 DOI: 10.1006/Nbdi.1999.0279 |
0.591 |
|
| 2000 |
Duff K, Malester B, Matsuoka Y, Picciano M, Helpern J, Merken M, Lewis J, Hutton M, Refolo L. Amyloid and tau mice: phenotype and phenotype modulation Biochemical Society Transactions. 28. DOI: 10.1042/Bst028A128C |
0.451 |
|
| 2000 |
Howlett DR, Duff K. Identification of kinases associated with phosphorylated tau deposits in the brains of transgenic mice bearing mutated amyloid precursor protein and presenilin-1 transgenes Neurobiology of Aging. 21: 224-225. DOI: 10.1016/S0197-4580(00)83341-2 |
0.451 |
|
| 2000 |
Wiebringhaus T, Wirak D, Altman R, Cahill K, Duff K, Ruhland M, Koenig G, Baumann K. The effect of presenilin on β-amyloid in knock-in mice carrying the human amyloid precursor protein with Swedish and/or London mutation Neurobiology of Aging. 21: 224. DOI: 10.1016/S0197-4580(00)83338-2 |
0.413 |
|
| 2000 |
Popp A, Hartmann E, Hagelschuer I, Bayer AG, Duff K, Wirak D, Unsworth C, Baumann K, Koenig G. β-amyloid plaques in amyloid precursor protein knock-in mice Neurobiology of Aging. 21: 223. DOI: 10.1016/S0197-4580(00)83336-9 |
0.417 |
|
| 2000 |
Gandy S, Petanceska SS, Frail DE, Simpkins J, Refolo L, Duff K. Estrogen status controls brain abeta levels in guinea pigs and in plaque-forming transgenic mice Neurobiology of Aging. 21: 213. DOI: 10.1016/S0197-4580(00)83286-8 |
0.413 |
|
| 2000 |
Hu L, Wong TP, Cote SL, Duff K, Cuello CA. Early differential alterations of cholinergic and non-cholinergic cortical presynaptic boutons in transgenic mice displaying amyloid deposition Neurobiology of Aging. 21: 89. DOI: 10.1016/S0197-4580(00)82623-8 |
0.402 |
|
| 2000 |
Duff K, Refolo LM, Hutton M, Davies P. Tau pathobiology in transgenic mouse models Neurobiology of Aging. 21: 76. DOI: 10.1016/S0197-4580(00)82565-8 |
0.58 |
|
| 2000 |
Poduslo JF, Wengenack TM, Curran GL, Whelan S, Duff K. Delivery of diagnostic proteins into the nervous system: Targeting of Alzheimer's amyloid plaques with polyamine-modified Aβ40 in APP, PS1 transgenic mice Neurobiology of Aging. 21: 131. DOI: 10.1016/S0197-4580(00)82390-8 |
0.49 |
|
| 2000 |
Refolo LM, Wang R, Tint SG, Sambamurti K, Francois JL, Duff K. Hypercholesterolemia accelerates amyloid pathology in a transgenic mouse model of Alzheimer's amyloidosis Neurobiology of Aging. 21: 125. DOI: 10.1016/S0197-4580(00)82363-5 |
0.496 |
|
| 2000 |
Wang R, Uljon SN, Troncoso JC, Duff K. Molecular anatomy of amyloid β-peptides in Alzheimer's disease patient's brain by mass spectrometry Neurobiology of Aging. 21: 155. DOI: 10.1016/S0197-4580(00)82033-3 |
0.379 |
|
| 2000 |
Nixon R, Duff K, Matsuoka Y. 26. The pathobiology of tau protein in neurodegenerative diseases Biological Psychiatry. 47: S7. DOI: 10.1016/S0006-3223(00)00292-4 |
0.411 |
|
| 1999 |
Wright KL, Morgan DG, Yu X, Goss JR, Salbaum JM, Duff K, Gordon MN. Mice transgenic for a human amyloid precursor protein promoter-lacZ reporter construct. Journal of Molecular Neuroscience : Mn. 13: 111-20. PMID 10691298 DOI: 10.1385/Jmn:13:1-2:111 |
0.377 |
|
| 1999 |
Holcomb LA, Gordon MN, Jantzen P, Hsiao K, Duff K, Morgan D. Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits. Behavior Genetics. 29: 177-85. PMID 10547924 DOI: 10.1023/A:1021691918517 |
0.418 |
|
| 1999 |
Steiner H, Duff K, Capell A, Romig H, Grim MG, Lincoln S, Hardy J, Yu X, Picciano M, Fechteler K, Citron M, Kopan R, Pesold B, Keck S, Baader M, et al. A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling. The Journal of Biological Chemistry. 274: 28669-73. PMID 10497236 DOI: 10.1074/Jbc.274.40.28669 |
0.536 |
|
| 1999 |
McGowan E, Sanders S, Iwatsubo T, Takeuchi A, Saido T, Zehr C, Yu X, Uljon S, Wang R, Mann D, Dickson D, Duff K. Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes. Neurobiology of Disease. 6: 231-44. PMID 10448051 DOI: 10.1006/Nbdi.1999.0243 |
0.657 |
|
| 1999 |
Grover A, Houlden H, Baker M, Adamson J, Lewis J, Prihar G, Pickering-Brown S, Duff K, Hutton M. 5' splice site mutations in tau associated with the inherited dementia FTDP-17 affect a stem-loop structure that regulates alternative splicing of exon 10. The Journal of Biological Chemistry. 274: 15134-43. PMID 10329720 DOI: 10.1074/Jbc.274.21.15134 |
0.458 |
|
| 1999 |
Wong TP, Debeir T, Duff K, Cuello AC. Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-1 and amyloid precursor protein transgenes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 2706-16. PMID 10087083 DOI: 10.1523/Jneurosci.19-07-02706.1999 |
0.43 |
|
| 1999 |
Begley JG, Duan W, Chan S, Duff K, Mattson MP. Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice. Journal of Neurochemistry. 72: 1030-9. PMID 10037474 DOI: 10.1046/J.1471-4159.1999.0721030.X |
0.407 |
|
| 1999 |
Duff K. Chapter 5.8 Transgenic mouse models of Alzheimer's disease Techniques in the Behavioral and Neural Sciences. 13: 880-894. DOI: 10.1016/S0921-0709(99)80065-0 |
0.489 |
|
| 1998 |
Hardy J, Duff K, Hardy KG, Perez-Tur J, Hutton M. Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau. Nature Neuroscience. 1: 355-8. PMID 10196523 DOI: 10.1038/1565 |
0.787 |
|
| 1998 |
Duff K. Recent work on Alzheimer's disease transgenics. Current Opinion in Biotechnology. 9: 561-4. PMID 9889140 DOI: 10.1016/S0958-1669(98)80132-8 |
0.5 |
|
| 1998 |
Duff K. Transgenic models for Alzheimer's disease. Neuropathology and Applied Neurobiology. 24: 101-3. PMID 9634205 DOI: 10.1046/J.1365-2990.1998.00006.X |
0.438 |
|
| 1998 |
Mehta ND, Refolo LM, Eckman C, Sanders S, Yager D, Perez-Tur J, Younkin S, Duff K, Hardy J, Hutton M. Increased Abeta42(43) from cell lines expressing presenilin 1 mutations. Annals of Neurology. 43: 256-8. PMID 9485068 DOI: 10.1002/Ana.410430217 |
0.754 |
|
| 1998 |
Holcomb L, Gordon MN, McGowan E, Yu X, Benkovic S, Jantzen P, Wright K, Saad I, Mueller R, Morgan D, Sanders S, Zehr C, O'Campo K, Hardy J, Prada CM, ... ... Duff K, et al. Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nature Medicine. 4: 97-100. PMID 9427614 DOI: 10.1038/Nm0198-097 |
0.695 |
|
| 1997 |
Duff K. Alzheimer transgenic mouse models come of age. Trends in Neurosciences. 20: 279-80. PMID 9223216 DOI: 10.1016/S0166-2236(97)01093-X |
0.4 |
|
| 1996 |
Ward RV, Davis JB, Gray CW, Barton AJ, Bresciani LG, Caivano M, Murphy VF, Duff K, Hutton M, Hardy J, Roberts GW, Karran EH. Presenilin-1 is processed into two major cleavage products in neuronal cell lines. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 5: 293-8. PMID 9117540 DOI: 10.1006/Neur.1996.0040 |
0.617 |
|
| 1996 |
Barton AJ, Crook BW, Karran EH, Brown F, Dewar D, Mann DM, Pearson RC, Graham DI, Hardy J, Hutton M, Duff K, Goate AM, Clark RF, Roberts GW. Alteration in brain presenilin 1 mRNA expression in early onset familial Alzheimer's disease. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 5: 213-8. PMID 8910899 DOI: 10.1006/Neur.1996.0029 |
0.717 |
|
| 1996 |
Prihar G, Fuldner RA, Perez-Tur J, Lincoln S, Duff K, Crook R, Hardy J, Philips CA, Venter C, Talbot C, Clark RF, Goate A, Li J, Potter H, Karran E, et al. Structure and alternative splicing of the presenilin-2 gene. Neuroreport. 7: 1680-4. PMID 8904781 DOI: 10.1097/00001756-199607080-00031 |
0.765 |
|
| 1996 |
Duff K, Eckman C, Zehr C, Yu X, Prada CM, Perez-tur J, Hutton M, Buee L, Harigaya Y, Yager D, Morgan D, Gordon MN, Holcomb L, Refolo L, Zenk B, et al. Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1. Nature. 383: 710-3. PMID 8878479 DOI: 10.1038/383710A0 |
0.76 |
|
| 1996 |
Hutton M, Busfield F, Wragg M, Crook R, Perez-Tur J, Clark RF, Prihar G, Talbot C, Phillips H, Wright K, Baker M, Lendon C, Duff K, Martinez A, Houlden H, et al. Complete analysis of the presenilin 1 gene in early onset Alzheimer's disease. Neuroreport. 7: 801-5. PMID 8733749 |
0.735 |
|
| 1996 |
Folkesson R, Kosciessa U, Duff K, Hardyt J, Lannfelt L, Winblad B. 81 Preparative isolation of intact 650 kb YAC-APP genomic DNA containing the Swedish amyloid precursor protein 670/671 mutation Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80083-2 |
0.33 |
|
| 1995 |
Perez-Tur J, Froelich S, Prihar G, Crook R, Baker M, Duff K, Wragg M, Busfield F, Lendon C, Clark RF. A mutation in Alzheimer's disease destroying a splice acceptor site in the presenilin-1 gene. Neuroreport. 7: 297-301. PMID 8742474 |
0.636 |
|
| 1995 |
Duff K, Hardy J. Alzheimer's disease. Mouse model made. Nature. 373: 476-7. PMID 7845455 DOI: 10.1038/373476A0 |
0.532 |
|
| 1995 |
Houlden H, Crook R, Duff K, Hutton M, Collinge J, Roques P, Rossor M, Hardy J. Apolipoprotein E alleles but neither apolipoprotein B nor apolipoprotein AI/CIII alleles are associated with late onset, familial Alzheimer's disease. Neuroscience Letters. 188: 202-4. PMID 7609909 DOI: 10.1016/0304-3940(95)11422-S |
0.66 |
|
| 1995 |
Perez-Tur J, Froelich S, Prihar G, Crook R, Baker M, Duff K, Wragg M, Busfield F, Lendon C, Clark RF, Roques P, Fuldner RA, Johnston J, Cowburn R, Forsell C, et al. A mutation in Alzheimer's disease destroying a splice acceptor site in the presenilin-1 gene. Neuroreport. 7: 297-301. DOI: 10.1097/00001756-199512000-00071 |
0.764 |
|
| 1994 |
Duff K. Modeling Alzheimer's disease in transgenic mice. The Journal of the Florida Medical Association. 81: 625-8. PMID 7964589 |
0.339 |
|
| 1994 |
Rempfer R, Crook R, Houlden H, Duff K, Hutton M, Roberts GW, Raghavan R, Perry R, Hardy J. Parkinson's disease, but not Alzheimer's disease, Lewy body variant associated with mutant alleles at cytochrome P450 gene. Lancet. 344: 815. PMID 7916091 DOI: 10.1016/S0140-6736(94)92370-1 |
0.612 |
|
| 1994 |
Crook R, Hardy J, Duff K. Single-day apolipoprotein E genotyping. Journal of Neuroscience Methods. 53: 125-7. PMID 7823614 DOI: 10.1016/0165-0270(94)90168-6 |
0.388 |
|
| 1993 |
Brown J, Gydesen S, Sorensen SA, Brun A, Duff K, Houlden H, Fidani L, Kullkarni S, Cummings J, Goate A. Exclusion mapping in familial non-specific dementia. Dementia (Basel, Switzerland). 4: 163-6. PMID 8401786 DOI: 10.1159/000107317 |
0.638 |
|
| 1993 |
Hardy J, Duff K. Heterogeneity in Alzheimer's disease. Annals of Medicine. 25: 437-40. PMID 8251141 DOI: 10.3109/07853899309147308 |
0.564 |
|
| 1993 |
Lannfelt L, Folkesson R, Mohammed AH, Winblad B, Hellgren D, Duff K, Hardy J. Alzheimer's disease: molecular genetics and transgenic animal models. Behavioural Brain Research. 57: 207-13. PMID 8117426 DOI: 10.1016/0166-4328(93)90137-F |
0.599 |
|
| 1992 |
Mullan M, Houlden H, Windelspecht M, Fidani L, Lombardi C, Diaz P, Rossor M, Crook R, Hardy J, Duff K. A locus for familial early-onset Alzheimer's disease on the long arm of chromosome 14, proximal to the alpha 1-antichymotrypsin gene. Nature Genetics. 2: 340-2. PMID 1303291 DOI: 10.1038/Ng1292-340 |
0.75 |
|
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