| Year |
Citation |
Score |
| 2023 |
Dahir NS, Gui Y, Wu Y, Sweeney PR, Williams SY, Gimenez LE, Sawyer TK, Joy ST, Mapp AK, Cone RD. Inhibition of the melanocortin-3 receptor (MC3R) causes generalized sensitization to anorectic agents. Biorxiv : the Preprint Server For Biology. PMID 38106197 DOI: 10.1101/2023.12.05.570114 |
0.347 |
|
| 2023 |
Gui Y, Dahir NS, Wu Y, Downing G, Sweeney P, Cone RD. Melanocortin-3 receptor expression in AgRP neurons is required for normal activation of the neurons in response to energy deficiency. Cell Reports. 42: 113188. PMID 37792535 DOI: 10.1016/j.celrep.2023.113188 |
0.338 |
|
| 2023 |
Gui Y, Dahir NS, Downing G, Sweeney P, Cone RD. Cell autonomous regulation of the activation of AgRP neurons by the melanocortin-3 receptor. Biorxiv : the Preprint Server For Biology. PMID 37425887 DOI: 10.1101/2023.06.28.546874 |
0.355 |
|
| 2021 |
Wang Q, Zhang P, Cakir I, Mi L, Cone RD, Lin JD. Deletion of the feeding-induced hepatokine TSK ameliorates the melanocortin obesity syndrome. Diabetes. PMID 34183373 DOI: 10.2337/db21-0161 |
0.308 |
|
| 2021 |
Sweeney P, Chen C, Rajapakse I, Cone RD. Network dynamics of hypothalamic feeding neurons. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33795520 DOI: 10.1073/pnas.2011140118 |
0.326 |
|
| 2020 |
Chen V, Bruno AE, Britt LL, Hernandez CC, Gimenez LE, Peisley A, Cone RD, Millhauser GL. Membrane Orientation and Oligomerization of the Melanocortin Receptor Accessory Protein 2. The Journal of Biological Chemistry. PMID 32943551 DOI: 10.1074/Jbc.Ra120.015482 |
0.334 |
|
| 2019 |
Shainer I, Michel M, Marquart GD, Bhandiwad AA, Zmora N, Ben-Moshe Livne Z, Zohar Y, Hazak A, Mazon Y, Förster D, Hollander-Cohen L, Cone RD, Burgess HA, Gothilf Y. Agouti-Related Protein 2 Is a New Player in the Teleost Stress Response System. Current Biology : Cb. PMID 31178320 DOI: 10.1016/J.Cub.2019.05.021 |
0.305 |
|
| 2018 |
Anderson EJP, Ghamari-Langroudi M, Cakir I, Litt MJ, Chen V, Reggiardo RE, Millhauser GL, Cone RD. Late onset obesity in mice with targeted deletion of potassium inward rectifier Kir7.1 from cells expressing the melanocortin-4 receptor. Journal of Neuroendocrinology. e12670. PMID 30561082 DOI: 10.1111/Jne.12670 |
0.503 |
|
| 2018 |
Carrington S, Hernandez C, Swale D, Aluko OA, Denton JS, Cone R. G protein-coupled receptors differentially regulate glycosylation and activity of the inwardly rectifying potassium channel Kir7.1. The Journal of Biological Chemistry. PMID 30257863 DOI: 10.1074/Jbc.Ra118.003238 |
0.304 |
|
| 2018 |
Ghamari-Langroudi M, Cakir I, Lippert RN, Sweeney P, Litt MJ, Ellacott KLJ, Cone RD. Regulation of energy rheostasis by the melanocortin-3 receptor. Science Advances. 4: eaat0866. PMID 30140740 DOI: 10.1126/Sciadv.Aat0866 |
0.395 |
|
| 2017 |
Collet TH, Dubern B, Mokrosinski J, Connors H, Keogh JM, Mendes de Oliveira E, Henning E, Poitou-Bernert C, Oppert JM, Tounian P, Marchelli F, Alili R, Le Beyec J, Pépin D, Lacorte JM, ... ... Cone RD, et al. Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency. Molecular Metabolism. 6: 1321-1329. PMID 29031731 DOI: 10.1016/J.Molmet.2017.06.015 |
0.406 |
|
| 2017 |
Litt MJ, Okoye GD, Lark D, Cakir I, Moore C, Barber MC, Atkinson J, Fessel J, Moslehi J, Cone RD. Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy. Elife. 6. PMID 28829041 DOI: 10.7554/Elife.28118 |
0.344 |
|
| 2017 |
Zhao L, Zhou X, Rokas A, Cone RD. Functional variants of the melanocortin-4 receptor associated with the Odontoceti and Mysticeti suborders of cetaceans. Scientific Reports. 7: 5684. PMID 28720755 DOI: 10.1038/S41598-017-05962-1 |
0.398 |
|
| 2017 |
Shainer I, Buchshtab A, Hawkins TA, Wilson SW, Cone RD, Gothilf Y. Novel hypophysiotropic AgRP2 neurons and pineal cells revealed by BAC transgenesis in zebrafish. Scientific Reports. 7: 44777. PMID 28317906 DOI: 10.1038/Srep44777 |
0.314 |
|
| 2017 |
Litt MJ, Okoye GD, Lark D, Cakir I, Moore C, Barber MC, Atkinson J, Fessel J, Moslehi J, Cone RD. Author response: Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy Elife. DOI: 10.7554/Elife.28118.028 |
0.335 |
|
| 2016 |
Guillot R, Cortés R, Navarro S, Mischitelli M, García-Herranz V, Sánchez E, Cal L, Navarro JC, Míguez J, Afanasyev S, Krasnov A, Cone RD, Rotllant J, Cerdá-Reverter JM. Behind melanocortin antagonist overexpression in the zebrafish brain: A behavioral and transcriptomic approach. Hormones and Behavior. PMID 27156808 DOI: 10.1016/J.Yhbeh.2016.04.011 |
0.412 |
|
| 2016 |
Anderson EJ, Cakir I, Carrington S, Cone R, Ghamari-Langroudi M, Gillyard T, Gimenez LE, Litt M. Regulation of feeding and energy homeostasis by α-MSH. Journal of Molecular Endocrinology. PMID 26939593 DOI: 10.1530/Jme-16-0014 |
0.425 |
|
| 2016 |
Michel M, Page-McCaw PS, Chen W, Cone RD. Leptin signaling regulates glucose homeostasis, but not adipostasis, in the zebrafish. Proceedings of the National Academy of Sciences of the United States of America. PMID 26903647 DOI: 10.1073/Pnas.1513212113 |
0.395 |
|
| 2015 |
Bingham NC, Cone RD. Regulation of orexigenic AgRP neurons: A third way? Trends in Endocrinology and Metabolism: Tem. 26: 339-40. PMID 26033032 DOI: 10.1016/J.Tem.2015.05.008 |
0.403 |
|
| 2015 |
Chen KY, Muniyappa R, Abel BS, Mullins KP, Staker P, Brychta RJ, Zhao X, Ring M, Psota TL, Cone RD, Panaro BL, Gottesdiener KM, Van der Ploeg LH, Reitman ML, Skarulis MC. RM-493, a melanocortin-4 receptor (MC4R) agonist, increases resting energy expenditure in obese individuals. The Journal of Clinical Endocrinology and Metabolism. 100: 1639-45. PMID 25675384 DOI: 10.1210/Jc.2014-4024 |
0.388 |
|
| 2015 |
Ghamari-Langroudi M, Digby GJ, Sebag JA, Millhauser GL, Palomino R, Matthews R, Gillyard T, Panaro BL, Tough IR, Cox HM, Denton JS, Cone RD. G-protein-independent coupling of MC4R to Kir7.1 in hypothalamic neurons. Nature. 520: 94-8. PMID 25600267 DOI: 10.1038/Nature14051 |
0.448 |
|
| 2015 |
Diaz Martinez M, Ghamari-Langroudi M, Gifford A, Cone R, Welch EB. Automated pipeline to analyze non-contact infrared images of the paraventricular nucleus specific leptin receptor knock-out mouse model Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9417. DOI: 10.1117/12.2082102 |
0.372 |
|
| 2014 |
Panaro BL, Tough IR, Engelstoft MS, Matthews RT, Digby GJ, Møller CL, Svendsen B, Gribble F, Reimann F, Holst JJ, Holst B, Schwartz TW, Cox HM, Cone RD. The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo. Cell Metabolism. 20: 1018-29. PMID 25453189 DOI: 10.1016/J.Cmet.2014.10.004 |
0.416 |
|
| 2014 |
Lippert RN, Ellacott KL, Cone RD. Gender-specific roles for the melanocortin-3 receptor in the regulation of the mesolimbic dopamine system in mice. Endocrinology. 155: 1718-27. PMID 24605830 DOI: 10.1210/En.2013-2049 |
0.392 |
|
| 2013 |
Eom J, Hong M, Cone RD, Song Y. Zebrafish ghrelin is expressed in pancreatic endocrine cells and regulated by metabolic state. Biochemical and Biophysical Research Communications. 439: 115-20. PMID 23954636 DOI: 10.1016/J.Bbrc.2013.08.017 |
0.386 |
|
| 2013 |
Sebag JA, Zhang C, Hinkle PM, Bradshaw AM, Cone RD. Developmental control of the melanocortin-4 receptor by MRAP2 proteins in zebrafish. Science (New York, N.Y.). 341: 278-81. PMID 23869017 DOI: 10.1126/Science.1232995 |
0.374 |
|
| 2013 |
Renquist BJ, Zhang C, Williams SY, Cone RD. Development of an assay for high-throughput energy expenditure monitoring in the zebrafish. Zebrafish. 10: 343-52. PMID 23705823 DOI: 10.1089/Zeb.2012.0841 |
0.364 |
|
| 2013 |
Panaro BL, Cone RD. Melanocortin-4 receptor mutations paradoxically reduce preference for palatable foods. Proceedings of the National Academy of Sciences of the United States of America. 110: 7050-5. PMID 23569235 DOI: 10.1073/Pnas.1304707110 |
0.371 |
|
| 2012 |
Renquist BJ, Murphy JG, Larson EA, Olsen D, Klein RF, Ellacott KL, Cone RD. Melanocortin-3 receptor regulates the normal fasting response. Proceedings of the National Academy of Sciences of the United States of America. 109: E1489-98. PMID 22573815 DOI: 10.1073/Pnas.1201994109 |
0.577 |
|
| 2012 |
Hatoum IJ, Stylopoulos N, Vanhoose AM, Boyd KL, Yin DP, Ellacott KL, Ma LL, Blaszczyk K, Keogh JM, Cone RD, Farooqi IS, Kaplan LM. Melanocortin-4 receptor signaling is required for weight loss after gastric bypass surgery. The Journal of Clinical Endocrinology and Metabolism. 97: E1023-31. PMID 22492873 DOI: 10.1210/Jc.2011-3432 |
0.348 |
|
| 2012 |
Zhang C, Forlano PM, Cone RD. AgRP and POMC neurons are hypophysiotropic and coordinately regulate multiple endocrine axes in a larval teleost. Cell Metabolism. 15: 256-64. PMID 22245570 DOI: 10.1016/J.Cmet.2011.12.014 |
0.376 |
|
| 2011 |
Cone RD, Simerly RB. Leptin grows up and gets a neural network. Neuron. 71: 4-6. PMID 21745633 DOI: 10.1016/J.Neuron.2011.06.033 |
0.378 |
|
| 2011 |
Ghamari-Langroudi M, Cone RD. Shining a light on energy homeostasis. Cell Metabolism. 13: 235-6. PMID 21356511 DOI: 10.1016/J.Cmet.2011.02.007 |
0.361 |
|
| 2011 |
Pantel J, Williams SY, Mi D, Sebag J, Corbin JD, Weaver CD, Cone RD. Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay. European Journal of Pharmacology. 660: 139-47. PMID 21296065 DOI: 10.1016/J.Ejphar.2011.01.031 |
0.375 |
|
| 2011 |
Srisai D, Gillum MP, Panaro BL, Zhang XM, Kotchabhakdi N, Shulman GI, Ellacott KL, Cone RD. Characterization of the hyperphagic response to dietary fat in the MC4R knockout mouse. Endocrinology. 152: 890-902. PMID 21239438 DOI: 10.1210/En.2010-0716 |
0.379 |
|
| 2011 |
Renquist BJ, Lippert RN, Sebag JA, Ellacott KL, Cone RD. Physiological roles of the melanocortin MC₃ receptor. European Journal of Pharmacology. 660: 13-20. PMID 21211527 DOI: 10.1016/J.Ejphar.2010.12.025 |
0.423 |
|
| 2011 |
Ghamari-Langroudi M, Srisai D, Cone RD. Multinodal regulation of the arcuate/paraventricular nucleus circuit by leptin. Proceedings of the National Academy of Sciences of the United States of America. 108: 355-60. PMID 21169216 DOI: 10.1073/Pnas.1016785108 |
0.456 |
|
| 2010 |
Zhang C, Song Y, Thompson DA, Madonna MA, Millhauser GL, Toro S, Varga Z, Westerfield M, Gamse J, Chen W, Cone RD. Pineal-specific agouti protein regulates teleost background adaptation. Proceedings of the National Academy of Sciences of the United States of America. 107: 20164-71. PMID 20980662 DOI: 10.1073/Pnas.1014941107 |
0.334 |
|
| 2010 |
Ghamari-Langroudi M, Vella KR, Srisai D, Sugrue ML, Hollenberg AN, Cone RD. Regulation of thyrotropin-releasing hormone-expressing neurons in paraventricular nucleus of the hypothalamus by signals of adiposity. Molecular Endocrinology (Baltimore, Md.). 24: 2366-81. PMID 20943814 DOI: 10.1210/Edrv.31.6.9983 |
0.43 |
|
| 2010 |
Date Y, Mondal MS, Kageyama H, Ghamari-Langroudi M, Takenoya F, Yamaguchi H, Shimomura Y, Mori M, Murakami N, Shioda S, Cone RD, Nakazato M. Neuropeptide W: an anorectic peptide regulated by leptin and metabolic state. Endocrinology. 151: 2200-10. PMID 20189998 DOI: 10.1210/En.2009-1153 |
0.503 |
|
| 2009 |
Gruber KA, Fan W, Akerberg H, Larhammar D, Chee MJ, Colmers WF, Cone RD. Neuropeptide Y and gamma-melanocyte stimulating hormone (gamma-MSH) share a common pressor mechanism of action. Endocrine. 35: 312-24. PMID 19363600 DOI: 10.1007/S12020-008-9141-3 |
0.454 |
|
| 2008 |
Sutton GM, Perez-Tilve D, Nogueiras R, Fang J, Kim JK, Cone RD, Gimble JM, Tschöp MH, Butler AA. The melanocortin-3 receptor is required for entrainment to meal intake. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12946-55. PMID 19036988 DOI: 10.1523/Jneurosci.3615-08.2008 |
0.391 |
|
| 2007 |
Ellacott KL, Murphy JG, Marks DL, Cone RD. Obesity-induced inflammation in white adipose tissue is attenuated by loss of melanocortin-3 receptor signaling. Endocrinology. 148: 6186-94. PMID 17901224 DOI: 10.1210/En.2007-0699 |
0.562 |
|
| 2007 |
Forlano PM, Cone RD. Conserved neurochemical pathways involved in hypothalamic control of energy homeostasis. The Journal of Comparative Neurology. 505: 235-48. PMID 17879270 DOI: 10.1002/Cne.21447 |
0.374 |
|
| 2007 |
Song Y, Cone RD. Creation of a genetic model of obesity in a teleost. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 2042-9. PMID 17341684 DOI: 10.1096/Fj.06-7503Com |
0.372 |
|
| 2007 |
Voss-Andreae A, Murphy JG, Ellacott KL, Stuart RC, Nillni EA, Cone RD, Fan W. Role of the central melanocortin circuitry in adaptive thermogenesis of brown adipose tissue. Endocrinology. 148: 1550-60. PMID 17194736 DOI: 10.1210/En.2006-1389 |
0.613 |
|
| 2006 |
Cone RD. Studies on the physiological functions of the melanocortin system. Endocrine Reviews. 27: 736-49. PMID 17077189 DOI: 10.1210/Er.2006-0034 |
0.44 |
|
| 2006 |
Ni XP, Butler AA, Cone RD, Humphreys MH. Central receptors mediating the cardiovascular actions of melanocyte stimulating hormones. Journal of Hypertension. 24: 2239-46. PMID 17053546 DOI: 10.1097/01.Hjh.0000249702.49854.Fa |
0.374 |
|
| 2006 |
Mak RH, Cheung W, Cone RD, Marks DL. Mechanisms of disease: Cytokine and adipokine signaling in uremic cachexia. Nature Clinical Practice. Nephrology. 2: 527-34. PMID 16941045 DOI: 10.1038/Ncpneph0273 |
0.316 |
|
| 2006 |
Ellacott KL, Cone RD. The role of the central melanocortin system in the regulation of food intake and energy homeostasis: lessons from mouse models. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 361: 1265-74. PMID 16815803 DOI: 10.1098/Rstb.2006.1861 |
0.383 |
|
| 2006 |
Ellacott KL, Halatchev IG, Cone RD. Characterization of leptin-responsive neurons in the caudal brainstem. Endocrinology. 147: 3190-5. PMID 16601142 DOI: 10.1210/En.2005-0877 |
0.774 |
|
| 2006 |
Mak RH, Cheung W, Cone RD, Marks DL. Leptin and inflammation-associated cachexia in chronic kidney disease. Kidney International. 69: 794-7. PMID 16518340 DOI: 10.1038/Sj.Ki.5000182 |
0.343 |
|
| 2006 |
Morgan C, Cone RD. Melanocortin-5 receptor deficiency in mice blocks a novel pathway influencing pheromone-induced aggression. Behavior Genetics. 36: 291-300. PMID 16408249 DOI: 10.1007/S10519-005-9024-9 |
0.348 |
|
| 2006 |
Ellacott KL, Halatchev IG, Cone RD. Interactions between gut peptides and the central melanocortin system in the regulation of energy homeostasis. Peptides. 27: 340-9. PMID 16309792 DOI: 10.1016/J.Peptides.2005.02.031 |
0.76 |
|
| 2006 |
Marks DL, Hruby V, Brookhart G, Cone RD. The regulation of food intake by selective stimulation of the type 3 melanocortin receptor (MC3R). Peptides. 27: 259-64. PMID 16274853 DOI: 10.1016/J.Peptides.2005.01.025 |
0.562 |
|
| 2005 |
Ghamari-Langroudi M, Colmers WF, Cone RD. PYY3-36 inhibits the action potential firing activity of POMC neurons of arcuate nucleus through postsynaptic Y2 receptors. Cell Metabolism. 2: 191-9. PMID 16154101 DOI: 10.1016/J.Cmet.2005.08.003 |
0.478 |
|
| 2005 |
Halatchev IG, Cone RD. Peripheral administration of PYY(3-36) produces conditioned taste aversion in mice. Cell Metabolism. 1: 159-68. PMID 16054059 DOI: 10.1016/J.Cmet.2005.02.003 |
0.775 |
|
| 2005 |
Cheung W, Yu PX, Little BM, Cone RD, Marks DL, Mak RH. Role of leptin and melanocortin signaling in uremia-associated cachexia. The Journal of Clinical Investigation. 115: 1659-65. PMID 15931394 DOI: 10.1172/Jci22521 |
0.399 |
|
| 2005 |
Cone RD. Anatomy and regulation of the central melanocortin system. Nature Neuroscience. 8: 571-8. PMID 15856065 DOI: 10.1038/Nn1455 |
0.419 |
|
| 2005 |
Mak RH, Cheung W, Cone RD, Marks DL. Orexigenic and anorexigenic mechanisms in the control of nutrition in chronic kidney disease. Pediatric Nephrology (Berlin, Germany). 20: 427-31. PMID 15662537 DOI: 10.1007/S00467-004-1789-1 |
0.377 |
|
| 2005 |
Takahashi KA, Cone RD. Fasting induces a large, leptin-dependent increase in the intrinsic action potential frequency of orexigenic arcuate nucleus neuropeptide Y/Agouti-related protein neurons. Endocrinology. 146: 1043-7. PMID 15591135 DOI: 10.1210/En.2004-1397 |
0.424 |
|
| 2004 |
Fekete C, Marks DL, Sarkar S, Emerson CH, Rand WM, Cone RD, Lechan RM. Effect of Agouti-related protein in regulation of the hypothalamic-pituitary-thyroid axis in the melanocortin 4 receptor knockout mouse. Endocrinology. 145: 4816-21. PMID 15256492 DOI: 10.1210/En.2004-0476 |
0.464 |
|
| 2004 |
Marks DL, Boucher N, Lanouette CM, Pérusse L, Brookhart G, Comuzzie AG, Chagnon YC, Cone RD. Ala67Thr polymorphism in the Agouti-related peptide gene is associated with inherited leanness in humans. American Journal of Medical Genetics. Part A. 126: 267-71. PMID 15054840 DOI: 10.1002/Ajmg.A.20600 |
0.342 |
|
| 2004 |
Cepoi D, Phillips T, Cismowski M, Goodfellow VS, Ling N, Cone RD, Fan W. Assessment of a small molecule melanocortin-4 receptor-specific agonist on energy homeostasis. Brain Research. 1000: 64-71. PMID 15053953 DOI: 10.1016/J.Brainres.2003.10.041 |
0.437 |
|
| 2004 |
Fan W, Ellacott KL, Halatchev IG, Takahashi K, Yu P, Cone RD. Cholecystokinin-mediated suppression of feeding involves the brainstem melanocortin system. Nature Neuroscience. 7: 335-6. PMID 15034587 DOI: 10.1038/Nn1214 |
0.769 |
|
| 2004 |
Halatchev IG, Ellacott KL, Fan W, Cone RD. Peptide YY3-36 inhibits food intake in mice through a melanocortin-4 receptor-independent mechanism. Endocrinology. 145: 2585-90. PMID 15016721 DOI: 10.1210/En.2003-1754 |
0.78 |
|
| 2004 |
Han G, Haskell-Luevano C, Kendall L, Bonner G, Hadley ME, Cone RD, Hruby VJ. De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach. Journal of Medicinal Chemistry. 47: 1514-26. PMID 14998337 DOI: 10.1021/Jm030452X |
0.608 |
|
| 2004 |
Morgan C, Thomas RE, Ma W, Novotny MV, Cone RD. Melanocortin-5 receptor deficiency reduces a pheromonal signal for aggression in male mice. Chemical Senses. 29: 111-5. PMID 14977807 DOI: 10.1093/Chemse/Bjh011 |
0.341 |
|
| 2004 |
Ellacott KL, Cone RD. The central melanocortin system and the integration of short- and long-term regulators of energy homeostasis. Recent Progress in Hormone Research. 59: 395-408. PMID 14749511 DOI: 10.1210/Rp.59.1.395 |
0.483 |
|
| 2004 |
Morgan C, Thomas RE, Cone RD. Melanocortin-5 receptor deficiency promotes defensive behavior in male mice. Hormones and Behavior. 45: 58-63. PMID 14733892 DOI: 10.1016/J.Yhbeh.2003.08.004 |
0.34 |
|
| 2004 |
Takahashi KA, Smart JL, Liu H, Cone RD. The anorexigenic fatty acid synthase inhibitor, C75, is a nonspecific neuronal activator. Endocrinology. 145: 184-93. PMID 14512433 DOI: 10.1210/En.2003-0337 |
0.405 |
|
| 2003 |
Song Y, Golling G, Thacker TL, Cone RD. Agouti-related protein (AGRP) is conserved and regulated by metabolic state in the zebrafish, Danio rerio. Endocrine. 22: 257-65. PMID 14709799 DOI: 10.1385/Endo:22:3:257 |
0.355 |
|
| 2003 |
Haqq AM, René P, Kishi T, Khong K, Lee CE, Liu H, Friedman JM, Elmquist JK, Cone RD. Characterization of a novel binding partner of the melanocortin-4 receptor: attractin-like protein. The Biochemical Journal. 376: 595-605. PMID 14531729 DOI: 10.1042/Bj20031241 |
0.404 |
|
| 2003 |
Morgan C, Urbanski HF, Fan W, Akil H, Cone RD. Pheromone-induced anorexia in male Syrian hamsters. American Journal of Physiology. Endocrinology and Metabolism. 285: E1028-38. PMID 12888484 DOI: 10.1152/Ajpendo.00010.2003 |
0.3 |
|
| 2003 |
Marks D, Cone RD. The role of the melanocortin-3 receptor in cachexia. Annals of the New York Academy of Sciences. 994: 258-66. PMID 12851324 DOI: 10.1111/J.1749-6632.2003.Tb03188.X |
0.321 |
|
| 2003 |
Butler AA, Cone RD. Knockout studies defining different roles for melanocortin receptors in energy homeostasis. Annals of the New York Academy of Sciences. 994: 240-5. PMID 12851322 DOI: 10.1111/J.1749-6632.2003.Tb03186.X |
0.447 |
|
| 2003 |
Cowley MA, Cone R, Enriori P, Louiselle I, Williams SM, Evans AE. Electrophysiological actions of peripheral hormones on melanocortin neurons. Annals of the New York Academy of Sciences. 994: 175-86. PMID 12851314 DOI: 10.1111/J.1749-6632.2003.Tb03178.X |
0.491 |
|
| 2003 |
Heisler LK, Cowley MA, Kishi T, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro J, Zigman JM, Cone RD, Elmquist JK. Central serotonin and melanocortin pathways regulating energy homeostasis. Annals of the New York Academy of Sciences. 994: 169-74. PMID 12851313 DOI: 10.1111/J.1749-6632.2003.Tb03177.X |
0.366 |
|
| 2003 |
Xu B, Goulding EH, Zang K, Cepoi D, Cone RD, Jones KR, Tecott LH, Reichardt LF. Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nature Neuroscience. 6: 736-42. PMID 12796784 DOI: 10.1038/Nn1073 |
0.394 |
|
| 2003 |
Ni XP, Pearce D, Butler AA, Cone RD, Humphreys MH. Genetic disruption of gamma-melanocyte-stimulating hormone signaling leads to salt-sensitive hypertension in the mouse. The Journal of Clinical Investigation. 111: 1251-8. PMID 12697744 DOI: 10.1172/Jci16993 |
0.314 |
|
| 2003 |
Appleyard SM, Hayward M, Young JI, Butler AA, Cone RD, Rubinstein M, Low MJ. A role for the endogenous opioid beta-endorphin in energy homeostasis. Endocrinology. 144: 1753-60. PMID 12697680 DOI: 10.1210/En.2002-221096 |
0.369 |
|
| 2003 |
Marks DL, Butler AA, Turner R, Brookhart G, Cone RD. Differential role of melanocortin receptor subtypes in cachexia. Endocrinology. 144: 1513-23. PMID 12639936 DOI: 10.1210/En.2002-221099 |
0.366 |
|
| 2003 |
Cowley MA, Smith RG, Diano S, Tschöp M, Pronchuk N, Grove KL, Strasburger CJ, Bidlingmaier M, Esterman M, Heiman ML, Garcia-Segura LM, Nillni EA, Mendez P, Low MJ, Sotonyi P, ... ... Cone RD, et al. The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron. 37: 649-61. PMID 12597862 DOI: 10.1016/S0896-6273(03)00063-1 |
0.436 |
|
| 2002 |
Butler AA, Cone RD. The melanocortin receptors: lessons from knockout models. Neuropeptides. 36: 77-84. PMID 12359499 DOI: 10.1054/Npep.2002.0890 |
0.43 |
|
| 2002 |
Batterham RL, Cowley MA, Small CJ, Herzog H, Cohen MA, Dakin CL, Wren AM, Brynes AE, Low MJ, Ghatei MA, Cone RD, Bloom SR. Gut hormone PYY(3-36) physiologically inhibits food intake. Nature. 418: 650-4. PMID 12167864 DOI: 10.1038/Nature00887 |
0.431 |
|
| 2001 |
Cone RD, Cowley MA, Butler AA, Fan W, Marks DL, Low MJ. The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. 25: S63-7. PMID 11840218 DOI: 10.1038/Sj.Ijo.0801913 |
0.485 |
|
| 2001 |
Butler AA, Cone RD. Knockout models resulting in the development of obesity. Trends in Genetics : Tig. 17: S50-4. PMID 11585677 DOI: 10.1016/S0168-9525(01)02481-7 |
0.328 |
|
| 2001 |
Khong K, Kurtz SE, Sykes RL, Cone RD. Expression of functional melanocortin-4 receptor in the hypothalamic GT1-1 cell line. Neuroendocrinology. 74: 193-201. PMID 11528221 DOI: 10.1159/000054686 |
0.423 |
|
| 2001 |
Cowley MA, Smart JL, Rubinstein M, Cerdán MG, Diano S, Horvath TL, Cone RD, Low MJ. Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature. 411: 480-4. PMID 11373681 DOI: 10.1038/35078085 |
0.459 |
|
| 2001 |
Butler AA, Marks DL, Fan W, Kuhn CM, Bartolome M, Cone RD. Melanocortin-4 receptor is required for acute homeostatic responses to increased dietary fat. Nature Neuroscience. 4: 605-11. PMID 11369941 DOI: 10.1038/88423 |
0.39 |
|
| 2001 |
Haskell-Luevano C, Cone RD, Monck EK, Wan YP. Structure activity studies of the melanocortin-4 receptor by in vitro mutagenesis: identification of agouti-related protein (AGRP), melanocortin agonist and synthetic peptide antagonist interaction determinants. Biochemistry. 40: 6164-79. PMID 11352754 DOI: 10.1021/Bi010025Q |
0.627 |
|
| 2001 |
Marks DL, Cone RD. Central melanocortins and the regulation of weight during acute and chronic disease. Recent Progress in Hormone Research. 56: 359-75. PMID 11237221 DOI: 10.1210/Rp.56.1.359 |
0.395 |
|
| 2000 |
Robinson SW, Dinulescu DM, Cone RD. Genetic models of obesity and energy balance in the mouse. Annual Review of Genetics. 34: 687-745. PMID 11092843 DOI: 10.1146/Annurev.Genet.34.1.687 |
0.315 |
|
| 2000 |
De Souza J, Butler AA, Cone RD. Disproportionate inhibition of feeding in A(y) mice by certain stressors: a cautionary note. Neuroendocrinology. 72: 126-32. PMID 10971147 DOI: 10.1159/000054579 |
0.368 |
|
| 2000 |
Butler AA, Kesterson RA, Khong K, Cullen MJ, Pelleymounter MA, Dekoning J, Baetscher M, Cone RD. A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse. Endocrinology. 141: 3518-21. PMID 10965927 DOI: 10.1210/endo.141.9.7791 |
0.307 |
|
| 2000 |
Fan W, Dinulescu DM, Butler AA, Zhou J, Marks DL, Cone RD. The central melanocortin system can directly regulate serum insulin levels. Endocrinology. 141: 3072-9. PMID 10965876 DOI: 10.1210/Endo.141.9.7665 |
0.342 |
|
| 2000 |
Cone RD. Haploinsufficiency of the melanocortin-4 receptor: part of a thrifty genotype? The Journal of Clinical Investigation. 106: 185-7. PMID 10903333 DOI: 10.1172/Jci10628 |
0.325 |
|
| 2000 |
Haskell-Luevano C, Lim S, Yuan W, Cone RD, Hruby VJ. Structure activity studies of the melanocortin antagonist SHU9119 modified at the 6, 7, 8, and 9 positions. Peptides. 21: 49-57. PMID 10704719 DOI: 10.1016/S0196-9781(99)00167-9 |
0.674 |
|
| 1999 |
Cowley MA, Pronchuk N, Fan W, Dinulescu DM, Colmers WF, Cone RD. Integration of NPY, AGRP, and melanocortin signals in the hypothalamic paraventricular nucleus: evidence of a cellular basis for the adipostat. Neuron. 24: 155-63. PMID 10677034 DOI: 10.1016/S0896-6273(00)80829-6 |
0.404 |
|
| 1999 |
Haskell-Luevano C, Rosenquist A, Souers A, Khong KC, Ellman JA, Cone RD. Compounds that activate the mouse melanocortin-1 receptor identified by screening a small molecule library based upon the beta-turn. Journal of Medicinal Chemistry. 42: 4380-7. PMID 10543881 DOI: 10.1021/Jm990190S |
0.567 |
|
| 1999 |
Cone RD. The Central Melanocortin System and Energy Homeostasis. Trends in Endocrinology and Metabolism: Tem. 10: 211-216. PMID 10407394 DOI: 10.1016/S1043-2760(99)00153-8 |
0.333 |
|
| 1999 |
Chen P, Li C, Haskell-Luevano C, Cone RD, Smith MS. Altered expression of agouti-related protein and its colocalization with neuropeptide Y in the arcuate nucleus of the hypothalamus during lactation. Endocrinology. 140: 2645-50. PMID 10342854 DOI: 10.1210/Endo.140.6.6829 |
0.648 |
|
| 1999 |
Haskell-Luevano C, Chen P, Li C, Chang K, Smith MS, Cameron JL, Cone RD. Characterization of the neuroanatomical distribution of agouti-related protein immunoreactivity in the rhesus monkey and the rat. Endocrinology. 140: 1408-15. PMID 10067869 DOI: 10.1210/Endo.140.3.6544 |
0.639 |
|
| 1999 |
VÃ¥ge DI, Klungland H, Lu D, Cone RD. Molecular and pharmacological characterization of dominant black coat color in sheep. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 10: 39-43. PMID 9892731 DOI: 10.1007/S003359900939 |
0.33 |
|
| 1998 |
Ni XP, Kesterson RA, Sharma SD, Hruby VJ, Cone RD, Wiedemann E, Humphreys MH. Prevention of reflex natriuresis after acute unilateral nephrectomy by melanocortin receptor antagonists. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 274: R931-R938. PMID 29586884 DOI: 10.1152/ajpregu.1998.274.4.R931 |
0.412 |
|
| 1998 |
Dinulescu DM, Fan W, Boston BA, McCall K, Lamoreux ML, Moore KJ, Montagno J, Cone RD. Mahogany (mg) stimulates feeding and increases basal metabolic rate independent of its suppression of agouti. Proceedings of the National Academy of Sciences of the United States of America. 95: 12707-12. PMID 9770550 DOI: 10.1073/Pnas.95.21.12707 |
0.379 |
|
| 1998 |
Ni XP, Kesterson RA, Sharma SD, Hruby VJ, Cone RD, Wiedemann E, Humphreys MH. Prevention of reflex natriuresis after acute unilateral nephrectomy by melanocortin receptor antagonists. The American Journal of Physiology. 274: R931-8. PMID 9575953 DOI: 10.1152/Ajpregu.1998.274.4.R931 |
0.434 |
|
| 1998 |
Lu D, Vage DI, Cone RD. A ligand-mimetic model for constitutive activation of the melanocortin-1 receptor. Molecular Endocrinology (Baltimore, Md.). 12: 592-604. PMID 9544994 DOI: 10.1210/Mend.12.4.0091 |
0.343 |
|
| 1997 |
Chen W, Kelly MA, Opitz-Araya X, Thomas RE, Low MJ, Cone RD. Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptides. Cell. 91: 789-98. PMID 9413988 DOI: 10.1016/S0092-8674(00)80467-5 |
0.403 |
|
| 1997 |
Boston BA, Blaydon KM, Varnerin J, Cone RD. Independent and additive effects of central POMC and leptin pathways on murine obesity. Science (New York, N.Y.). 278: 1641-4. PMID 9374468 DOI: 10.1126/Science.278.5343.1641 |
0.38 |
|
| 1997 |
Kesterson RA, Huszar D, Lynch CA, Simerly RB, Cone RD. Induction of neuropeptide Y gene expression in the dorsal medial hypothalamic nucleus in two models of the agouti obesity syndrome. Molecular Endocrinology (Baltimore, Md.). 11: 630-7. PMID 9139806 DOI: 10.1210/Mend.11.5.9921 |
0.415 |
|
| 1997 |
VÃ¥ge DI, Lu D, Klungland H, Lien S, Adalsteinsson S, Cone RD. A non-epistatic interaction of agouti and extension in the fox, Vulpes vulpes. Nature Genetics. 15: 311-5. PMID 9054949 DOI: 10.1038/Ng0397-311 |
0.367 |
|
| 1997 |
Huszar D, Lynch CA, Fairchild-Huntress V, Dunmore JH, Fang Q, Berkemeier LR, Gu W, Kesterson RA, Boston BA, Cone RD, Smith FJ, Campfield LA, Burn P, Lee F. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell. 88: 131-41. PMID 9019399 DOI: 10.1016/S0092-8674(00)81865-6 |
0.404 |
|
| 1997 |
Fan W, Boston BA, Kesterson RA, Hruby VJ, Cone RD. Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature. 385: 165-8. PMID 8990120 DOI: 10.1038/385165A0 |
0.586 |
|
| 1996 |
Boston BA, Cone RD. Characterization of melanocortin receptor subtype expression in murine adipose tissues and in the 3T3-L1 cell line. Endocrinology. 137: 2043-50. PMID 8612546 DOI: 10.1210/Endo.137.5.8612546 |
0.387 |
|
| 1996 |
Li S, Varga K, Archer P, Hruby VJ, Sharma SD, Kesterson RA, Cone RD, Kunos G. Melanocortin Antagonists Define Two Distinct Pathways of Cardiovascular Control by α- and γ-Melanocyte-Stimulating Hormones The Journal of Neuroscience. 16: 5182-5188. DOI: 10.1523/Jneurosci.16-16-05182.1996 |
0.502 |
|
| 1995 |
Chen W, Shields TS, Stork PJ, Cone RD. A colorimetric assay for measuring activation of Gs- and Gq-coupled signaling pathways. Analytical Biochemistry. 226: 349-54. PMID 7793637 DOI: 10.1006/Abio.1995.1235 |
0.354 |
|
| 1995 |
Hruby VJ, Lu D, Sharma SD, Castrucci AL, Kesterson RA, al-Obeidi FA, Hadley ME, Cone RD. Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors. Journal of Medicinal Chemistry. 38: 3454-61. PMID 7658432 DOI: 10.1021/Jm00018A005 |
0.491 |
|
| 1995 |
Stenzel P, Kesterson R, Yeung W, Cone RD, Rittenberg MB, Stenzel-Poore MP. Identification of a novel murine receptor for corticotropin-releasing hormone expressed in the heart. Molecular Endocrinology (Baltimore, Md.). 9: 637-45. PMID 7565810 DOI: 10.1210/Mend.9.5.7565810 |
0.419 |
|
| 1994 |
Mountjoy KG, Bird IM, Rainey WE, Cone RD. ACTH induces up-regulation of ACTH receptor mRNA in mouse and human adrenocortical cell lines. Molecular and Cellular Endocrinology. 99: R17-20. PMID 8187950 DOI: 10.1016/0303-7207(94)90160-0 |
0.328 |
|
| 1994 |
Magenis RE, Smith L, Nadeau JH, Johnson KR, Mountjoy KG, Cone RD. Mapping of the ACTH, MSH, and neural (MC3 and MC4) melanocortin receptors in the mouse and human. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 5: 503-8. PMID 7949735 DOI: 10.1007/Bf00369320 |
0.362 |
|
| 1994 |
Lu D, Willard D, Patel IR, Kadwell S, Overton L, Kost T, Luther M, Chen W, Woychik RP, Wilkison WO, Cone RD. Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor Nature. 371: 799-802. PMID 7935841 DOI: 10.1038/371799A0 |
0.395 |
|
| 1994 |
Mountjoy KG, Mortrud MT, Low MJ, Simerly RB, Cone RD. Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain. Molecular Endocrinology (Baltimore, Md.). 8: 1298-308. PMID 7854347 DOI: 10.1210/Mend.8.10.7854347 |
0.397 |
|
| 1994 |
Low MJ, Simerly RB, Cone RD. Receptors for the melanocortin peptides in the central nervous system Current Opinion in Endocrinology and Diabetes. 1: 79-88. DOI: 10.1097/00060793-199400010-00016 |
0.386 |
|
| 1993 |
Cone RD, Mountjoy KG. Molecular genetics of the ACTH and melanocyte-stimulating hormone receptors. Trends in Endocrinology and Metabolism: Tem. 4: 242-7. PMID 18407163 DOI: 10.1016/1043-2760(93)90129-3 |
0.384 |
|
| 1993 |
Robbins LS, Nadeau JH, Johnson KR, Kelly MA, Roselli-Rehfuss L, Baack E, Mountjoy KG, Cone RD. Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function. Cell. 72: 827-34. PMID 8458079 DOI: 10.1016/0092-8674(93)90572-8 |
0.353 |
|
| 1993 |
Roselli-Rehfuss L, Mountjoy KG, Robbins LS, Mortrud MT, Low MJ, Tatro JB, Entwistle ML, Simerly RB, Cone RD. Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system. Proceedings of the National Academy of Sciences of the United States of America. 90: 8856-60. PMID 8415620 DOI: 10.1073/Pnas.90.19.8856 |
0.458 |
|
| 1993 |
Cone RD, Mountjoy KG, Robbins LS, Nadeau JH, Johnson KR, Roselli-Rehfuss L, Mortrud MT. Cloning and functional characterization of a family of receptors for the melanotropic peptides. Annals of the New York Academy of Sciences. 680: 342-63. PMID 8390157 DOI: 10.1111/J.1749-6632.1993.Tb19694.X |
0.341 |
|
| 1992 |
Roselli-Rehfuss L, Robbins LS, Cone RD. Thyrotropin receptor messenger ribonucleic acid is expressed in most brown and white adipose tissues in the guinea pig. Endocrinology. 130: 1857-61. PMID 1547715 DOI: 10.1210/Endo.130.4.1547715 |
0.326 |
|
| 1992 |
Cone RD, Mulligan RC. High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range. 1984. Biotechnology (Reading, Mass.). 24: 420-4. PMID 1384843 |
0.383 |
|
| 1992 |
Woloshin PI, Walton KM, Rehfuss RP, Goodman RH, Cone RD. 3',5'-cyclic adenosine monophosphate-regulated enhancer binding (CREB) activity is required for normal growth and differentiated phenotype in the FRTL5 thyroid follicular cell line. Molecular Endocrinology (Baltimore, Md.). 6: 1725-33. PMID 1333055 DOI: 10.1210/Mend.6.10.1333055 |
0.315 |
|
| 1992 |
Mountjoy KG, Robbins LS, Mortrud MT, Cone RD. The cloning of a family of genes that encode the melanocortin receptors. Science (New York, N.Y.). 257: 1248-51. PMID 1325670 DOI: 10.1126/Science.1325670 |
0.409 |
|
| 1990 |
Frazier AL, Robbins LS, Stork PJ, Sprengel R, Segaloff DL, Cone RD. Isolation of TSH and LH/CG receptor cDNAs from human thyroid: regulation by tissue specific splicing. Molecular Endocrinology (Baltimore, Md.). 4: 1264-76. PMID 2293030 DOI: 10.1210/Mend-4-8-1264 |
0.358 |
|
| 1990 |
Zhou QY, Grandy DK, Thambi L, Kushner JA, Van Tol HH, Cone R, Pribnow D, Salon J, Bunzow JR, Civelli O. Cloning and expression of human and rat D1 dopamine receptors. Nature. 347: 76-80. PMID 2168520 DOI: 10.1038/347076A0 |
0.333 |
|
| 1988 |
Weber-Benarous A, Cone RD, London IM, Mulligan RC. Retroviral-mediated transfer and expression of human beta-globin genes in cultured murine and human erythroid cells. The Journal of Biological Chemistry. 263: 6142-5. PMID 3162912 |
0.407 |
|
| 1987 |
Cone RD, Reilly EB, Eisen HN, Mulligan RC. Tissue-specific expression of functionally rearranged lambda 1 Ig gene through a retrovirus vector. Science (New York, N.Y.). 236: 954-7. PMID 3107128 DOI: 10.1126/Science.3107128 |
0.481 |
|
| 1987 |
Cone RD, Weber-Benarous A, Baorto D, Mulligan RC. Regulated expression of a complete human beta-globin gene encoded by a transmissible retrovirus vector. Molecular and Cellular Biology. 7: 887-97. PMID 3029570 DOI: 10.1128/Mcb.7.2.887 |
0.439 |
|
| 1986 |
Soriano P, Cone RD, Mulligan RC, Jaenisch R. Tissue-specific and ectopic expression of genes introduced into transgenic mice by retroviruses. Science (New York, N.Y.). 234: 1409-13. PMID 3024318 DOI: 10.1126/Science.3024318 |
0.499 |
|
| 1986 |
Uchida N, Cone RD, Freeman GJ, Mulligan RC, Cantor H. High efficiency gene transfer into murine T cell clones using a retroviral vector. Journal of Immunology (Baltimore, Md. : 1950). 136: 1876-9. PMID 3005404 |
0.396 |
|
| 1984 |
Cone RD, Mulligan RC. High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range. Proceedings of the National Academy of Sciences of the United States of America. 81: 6349-53. PMID 6093098 DOI: 10.1073/Pnas.81.20.6349 |
0.461 |
|
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