Howard Schulman - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
calcium signaling

113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Chen X, Cai Q, Zhou J, Pleasure SJ, Schulman H, Zhang M, Nicoll RA. CaMKII autophosphorylation is the only enzymatic event required for synaptic memory. Proceedings of the National Academy of Sciences of the United States of America. 121: e2402783121. PMID 38889145 DOI: 10.1073/pnas.2402783121  0.356
2023 Chen X, Cai Q, Zhou J, Pleasure SJ, Schulman H, Zhang M, Nicoll RA. CaMKII autophosphorylation but not downstream kinase activity is required for synaptic memory. Biorxiv : the Preprint Server For Biology. PMID 37662326 DOI: 10.1101/2023.08.25.554912  0.317
2023 Tullis JE, Larsen ME, Rumian NL, Freund RK, Boxer EE, Brown CN, Coultrap SJ, Schulman H, Aoto J, Dell'Acqua ML, Bayer KU. LTP induction by structural rather than enzymatic functions of CaMKII. Nature. PMID 37648853 DOI: 10.1038/s41586-023-06465-y  0.627
2020 Bhattacharyya M, Lee YK, Muratcioglu S, Qiu B, Nyayapati P, Schulman H, Groves JT, Kuriyan J. Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation. Elife. 9. PMID 32149607 DOI: 10.7554/Elife.53670  0.506
2019 Bayer KU, Schulman H. CaM Kinase: Still Inspiring at 40. Neuron. 103: 380-394. PMID 31394063 DOI: 10.1016/j.neuron.2019.05.033  0.686
2019 Pandini A, Schulman H, Khan S. Conformational coupling by trans-phosphorylation in calcium calmodulin dependent kinase II. Plos Computational Biology. 15: e1006796. PMID 31150387 DOI: 10.1371/journal.pcbi.1006796  0.432
2017 Neef S, Steffens A, Pellicena P, Mustroph J, Lebek S, Ort KR, Schulman H, Maier LS. Improvement of cardiomyocyte function by a novel pyrimidine-based CaMKII-inhibitor. Journal of Molecular and Cellular Cardiology. PMID 29294328 DOI: 10.1016/j.yjmcc.2017.12.015  0.476
2016 Bhattacharyya M, Stratton MM, Going CC, McSpadden ED, Huang Y, Susa AC, Elleman A, Cao YM, Pappireddi N, Burkhardt P, Gee CL, Barros T, Schulman H, Williams ER, Kuriyan J. Molecular mechanism of activation-triggered subunit exchange in Ca(2+)/calmodulin-dependent protein kinase II. Elife. 5. PMID 26949248 DOI: 10.7554/Elife.13405  0.527
2016 Bhattacharyya M, Stratton MM, Going CC, McSpadden ED, Huang Y, Susa AC, Elleman A, Cao YM, Pappireddi N, Burkhardt P, Gee CL, Barros T, Schulman H, Williams ER, Kuriyan J. Author response: Molecular mechanism of activation-triggered subunit exchange in Ca2+/calmodulin-dependent protein kinase II Elife. DOI: 10.7554/Elife.13405.039  0.552
2014 Pellicena P, Schulman H. CaMKII inhibitors: from research tools to therapeutic agents. Frontiers in Pharmacology. 5: 21. PMID 24600394 DOI: 10.3389/fphar.2014.00021  0.381
2014 Stratton M, Lee IH, Bhattacharyya M, Christensen SM, Chao LH, Schulman H, Groves JT, Kuriyan J. Correction: Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity. Elife. 3: e02490. PMID 24520169 DOI: 10.7554/Elife.02490  0.428
2014 Stratton M, Lee IH, Bhattacharyya M, Christensen SM, Chao LH, Schulman H, Groves JT, Kuriyan J. Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity. Elife. 3: e01610. PMID 24473075 DOI: 10.7554/Elife.01610  0.503
2013 Stratton MM, Chao LH, Schulman H, Kuriyan J. Structural studies on the regulation of Ca2+/calmodulin dependent protein kinase II. Current Opinion in Structural Biology. 23: 292-301. PMID 23632248 DOI: 10.1016/J.Sbi.2013.04.002  0.544
2011 Chao LH, Stratton MM, Lee IH, Rosenberg OS, Levitz J, Mandell DJ, Kortemme T, Groves JT, Schulman H, Kuriyan J. A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin- dependent kinase II holoenzyme. Cell. 146: 732-45. PMID 21884935 DOI: 10.1016/J.Cell.2011.07.038  0.476
2010 Schulman H, Anderson ME. Ca/Calmodulin-dependent Protein Kinase II in Heart Failure. Drug Discovery Today. Disease Mechanisms. 7: e117-e122. PMID 21503275 DOI: 10.1016/j.ddmec.2010.07.005  0.473
2010 Chao LH, Pellicena P, Deindl S, Barclay LA, Schulman H, Kuriyan J. Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation. Nature Structural & Molecular Biology. 17: 264-72. PMID 20139983 DOI: 10.1038/Nsmb.1751  0.529
2006 Anderson ME, Higgins LS, Schulman H. Disease mechanisms and emerging therapies: protein kinases and their inhibitors in myocardial disease. Nature Clinical Practice. Cardiovascular Medicine. 3: 437-45. PMID 16874356 DOI: 10.1038/ncpcardio0585  0.431
2006 Bayer KU, LeBel E, McDonald GL, O'Leary H, Schulman H, De Koninck P. Transition from reversible to persistent binding of CaMKII to postsynaptic sites and NR2B. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1164-74. PMID 16436603 DOI: 10.1523/JNEUROSCI.3116-05.2006  0.776
2005 Hudmon A, Schulman H, Kim J, Maltez JM, Tsien RW, Pitt GS. CaMKII tethers to L-type Ca2+ channels, establishing a local and dedicated integrator of Ca2+ signals for facilitation. The Journal of Cell Biology. 171: 537-47. PMID 16275756 DOI: 10.1083/Jcb.200505155  0.488
2005 Hudmon A, Lebel E, Roy H, Sik A, Schulman H, Waxham MN, De Koninck P. A mechanism for Ca2+/calmodulin-dependent protein kinase II clustering at synaptic and nonsynaptic sites based on self-association. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6971-83. PMID 16049173 DOI: 10.1523/Jneurosci.4698-04.2005  0.748
2005 Tsui J, Inagaki M, Schulman H. Calcium/calmodulin-dependent protein kinase II (CaMKII) localization acts in concert with substrate targeting to create spatial restriction for phosphorylation. The Journal of Biological Chemistry. 280: 9210-6. PMID 15582994 DOI: 10.1074/jbc.M407653200  0.66
2004 Schulman H. Activity-dependent regulation of calcium/calmodulin-dependent protein kinase II localization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8399-403. PMID 15456811 DOI: 10.1523/JNEUROSCI.3606-04.2004  0.546
2003 Bradshaw JM, Kubota Y, Meyer T, Schulman H. An ultrasensitive Ca2+/calmodulin-dependent protein kinase II-protein phosphatase 1 switch facilitates specificity in postsynaptic calcium signaling. Proceedings of the National Academy of Sciences of the United States of America. 100: 10512-7. PMID 12928489 DOI: 10.1073/Pnas.1932759100  0.576
2003 Fink CC, Bayer KU, Myers JW, Ferrell JE, Schulman H, Meyer T. Selective regulation of neurite extension and synapse formation by the beta but not the alpha isoform of CaMKII. Neuron. 39: 283-97. PMID 12873385 DOI: 10.1016/S0896-6273(03)00428-8  0.611
2002 Leonard AS, Bayer KU, Merrill MA, Lim IA, Shea MA, Schulman H, Hell JW. Regulation of calcium/calmodulin-dependent protein kinase II docking to N-methyl-D-aspartate receptors by calcium/calmodulin and alpha-actinin. The Journal of Biological Chemistry. 277: 48441-8. PMID 12379661 DOI: 10.1074/Jbc.M205164200  0.612
2002 Bayer KU, De Koninck P, Schulman H. Alternative splicing modulates the frequency-dependent response of CaMKII to Ca(2+) oscillations. The Embo Journal. 21: 3590-7. PMID 12110572 DOI: 10.1093/emboj/cdf360  0.787
2002 Hudmon A, Schulman H. Neuronal CA2+/calmodulin-dependent protein kinase II: the role of structure and autoregulation in cellular function. Annual Review of Biochemistry. 71: 473-510. PMID 12045104 DOI: 10.1146/Annurev.Biochem.71.110601.135410  0.566
2002 Lisman J, Schulman H, Cline H. The molecular basis of CaMKII function in synaptic and behavioural memory. Nature Reviews. Neuroscience. 3: 175-90. PMID 11994750 DOI: 10.1038/nrn753  0.419
2002 Hudmon A, Schulman H. Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase II. The Biochemical Journal. 364: 593-611. PMID 11931644 DOI: 10.1042/Bj20020228  0.567
2002 Bradshaw JM, Hudmon A, Schulman H. Chemical quenched flow kinetic studies indicate an intraholoenzyme autophosphorylation mechanism for Ca2+/calmodulin-dependent protein kinase II. The Journal of Biological Chemistry. 277: 20991-8. PMID 11925447 DOI: 10.1074/Jbc.M202154200  0.557
2002 Fladmark KE, Brustugun OT, Mellgren G, Krakstad C, Boe R, Vintermyr OK, Schulman H, Doskeland SO. Ca2+/calmodulin-dependent protein kinase II is required for microcystin-induced apoptosis. The Journal of Biological Chemistry. 277: 2804-11. PMID 11713251 DOI: 10.1074/jbc.M109049200  0.423
2002 Zhang T, Johnson EN, Gu Y, Morissette MR, Sah VP, Gigena MS, Belke DD, Dillmann WH, Rogers TB, Schulman H, Ross J, Brown JH. The cardiac-specific nuclear delta(B) isoform of Ca2+/calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity. The Journal of Biological Chemistry. 277: 1261-7. PMID 11694533 DOI: 10.1074/Jbc.M108525200  0.342
2001 Bayer KU, Schulman H. Regulation of signal transduction by protein targeting: the case for CaMKII. Biochemical and Biophysical Research Communications. 289: 917-23. PMID 11741277 DOI: 10.1006/bbrc.2001.6063  0.684
2001 Bayer KU, De Koninck P, Leonard AS, Hell JW, Schulman H. Interaction with the NMDA receptor locks CaMKII in an active conformation. Nature. 411: 801-5. PMID 11459059 DOI: 10.1038/35081080  0.777
2001 Pitt GS, Zühlke RD, Hudmon A, Schulman H, Reuter H, Tsien RW. Molecular basis of calmodulin tethering and Ca2+-dependent inactivation of L-type Ca2+ channels. The Journal of Biological Chemistry. 276: 30794-802. PMID 11408490 DOI: 10.1074/Jbc.M104959200  0.475
2001 Singla SI, Hudmon A, Goldberg JM, Smith JL, Schulman H. Molecular characterization of calmodulin trapping by calcium/calmodulin-dependent protein kinase II. The Journal of Biological Chemistry. 276: 29353-60. PMID 11384969 DOI: 10.1074/Jbc.M101744200  0.528
2001 Chen YA, Scales SJ, Duvvuri V, Murthy M, Patel SM, Schulman H, Scheller RH. Calcium regulation of exocytosis in PC12 cells. The Journal of Biological Chemistry. 276: 26680-7. PMID 11359785 DOI: 10.1074/jbc.M103522200  0.744
2000 Braun AP, Heist EK, Schulman H. Inhibition of a mammalian large conductance, calcium-sensitive K+ channel by calmodulin-binding peptides. The Journal of Physiology. 527: 479-92. PMID 10990535 DOI: 10.1111/J.1469-7793.2000.00479.X  0.556
1999 Chen YA, Duvvuri V, Schulman H, Scheller RH. Calmodulin and protein kinase C increase Ca(2+)-stimulated secretion by modulating membrane-attached exocytic machinery. The Journal of Biological Chemistry. 274: 26469-76. PMID 10473607 DOI: 10.1074/jbc.274.37.26469  0.77
1999 Yang E, Schulman H. Structural examination of autoregulation of multifunctional calcium/calmodulin-dependent protein kinase II. The Journal of Biological Chemistry. 274: 26199-208. PMID 10473573 DOI: 10.1074/jbc.274.37.26199  0.507
1999 Brocke L, Chiang LW, Wagner PD, Schulman H. Functional implications of the subunit composition of neuronal CaM kinase II. The Journal of Biological Chemistry. 274: 22713-22. PMID 10428854 DOI: 10.1074/jbc.274.32.22713  0.434
1999 Bayer KU, Löhler J, Schulman H, Harbers K. Developmental expression of the CaM kinase II isoforms: ubiquitous gamma- and delta-CaM kinase II are the early isoforms and most abundant in the developing nervous system. Brain Research. Molecular Brain Research. 70: 147-54. PMID 10381553 DOI: 10.1016/S0169-328X(99)00131-X  0.661
1999 Patel R, Holt M, Philipova R, Moss S, Schulman H, Hidaka H, Whitaker M. Calcium/calmodulin-dependent phosphorylation and activation of human Cdc25-C at the G2/M phase transition in HeLa cells. The Journal of Biological Chemistry. 274: 7958-68. PMID 10075693 DOI: 10.1074/jbc.274.12.7958  0.347
1998 Anderson ME, Braun AP, Wu Y, Lu T, Wu Y, Schulman H, Sung RJ. KN-93, an inhibitor of multifunctional Ca++/calmodulin-dependent protein kinase, decreases early afterdepolarizations in rabbit heart. The Journal of Pharmacology and Experimental Therapeutics. 287: 996-1006. PMID 9864285  0.422
1998 Rich RC, Schulman H. Substrate-directed function of calmodulin in autophosphorylation of Ca2+/calmodulin-dependent protein kinase II. The Journal of Biological Chemistry. 273: 28424-9. PMID 9774470 DOI: 10.1074/Jbc.273.43.28424  0.515
1998 Bayer KU, Harbers K, Schulman H. alphaKAP is an anchoring protein for a novel CaM kinase II isoform in skeletal muscle. The Embo Journal. 17: 5598-605. PMID 9755160 DOI: 10.1093/emboj/17.19.5598  0.68
1998 Heist EK, Srinivasan M, Schulman H. Phosphorylation at the nuclear localization signal of Ca2+/calmodulin-dependent protein kinase II blocks its nuclear targeting. The Journal of Biological Chemistry. 273: 19763-71. PMID 9677407 DOI: 10.1074/jbc.273.31.19763  0.687
1998 Heist EK, Schulman H. The role of Ca2+/calmodulin-dependent protein kinases within the nucleus. Cell Calcium. 23: 103-14. PMID 9601605 DOI: 10.1016/S0143-4160(98)90108-7  0.718
1998 De Koninck P, Schulman H. Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations. Science (New York, N.Y.). 279: 227-30. PMID 9422695 DOI: 10.1126/science.279.5348.227  0.757
1997 Ramirez MT, Zhao XL, Schulman H, Brown JH. The nuclear deltaB isoform of Ca2+/calmodulin-dependent protein kinase II regulates atrial natriuretic factor gene expression in ventricular myocytes. The Journal of Biological Chemistry. 272: 31203-8. PMID 9388275  0.406
1996 Meffert MK, Calakos NC, Scheller RH, Schulman H. Nitric oxide modulates synaptic vesicle docking fusion reactions. Neuron. 16: 1229-36. PMID 8663999 DOI: 10.1016/S0896-6273(00)80149-X  0.715
1995 Deisseroth K, Bito H, Schulman H, Tsien RW. Synaptic plasticity: A molecular mechanism for metaplasticity. Current Biology : Cb. 5: 1334-8. PMID 8749377 DOI: 10.1016/S0960-9822(95)00262-4  0.34
1995 Braun AP, Schulman H. A non-selective cation current activated via the multifunctional Ca(2+)-calmodulin-dependent protein kinase in human epithelial cells. The Journal of Physiology. 488: 37-55. PMID 8568664 DOI: 10.1113/jphysiol.1995.sp020944  0.339
1995 Mestek A, Hurley JH, Bye LS, Campbell AD, Chen Y, Tian M, Liu J, Schulman H, Yu L. The human mu opioid receptor: modulation of functional desensitization by calcium/calmodulin-dependent protein kinase and protein kinase C. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 2396-406. PMID 7891175  0.319
1995 Braun AP, Schulman H. The multifunctional calcium/calmodulin-dependent protein kinase: from form to function. Annual Review of Physiology. 57: 417-45. PMID 7778873 DOI: 10.1146/annurev.ph.57.030195.002221  0.425
1995 Schulman H. Protein phosphorylation in neuronal plasticity and gene expression. Current Opinion in Neurobiology. 5: 375-81. PMID 7580161 DOI: 10.1016/0959-4388(95)80051-4  0.374
1995 Schulman H, Heist K, Srinivasan M. Decoding Ca2+ signals to the nucleus by multifunctional CaM kinase. Progress in Brain Research. 105: 95-104. PMID 7568901 DOI: 10.1016/S0079-6123(08)63287-2  0.592
1995 Brocke L, Srinivasan M, Schulman H. Developmental and regional expression of multifunctional Ca2+/calmodulin-dependent protein kinase isoforms in rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 6797-808. PMID 7472438 DOI: 10.1523/Jneurosci.15-10-06797.1995  0.461
1994 Hanson PI, Meyer T, Stryer L, Schulman H. Dual role of calmodulin in autophosphorylation of multifunctional CaM kinase may underlie decoding of calcium signals. Neuron. 12: 943-56. PMID 8185953 DOI: 10.1016/0896-6273(94)90306-9  0.698
1994 Edman CF, Schulman H. Identification and characterization of delta B-CaM kinase and delta C-CaM kinase from rat heart, two new multifunctional Ca2+/calmodulin-dependent protein kinase isoforms. Biochimica Et Biophysica Acta. 1221: 89-101. PMID 8130281 DOI: 10.1016/0167-4889(94)90221-6  0.536
1994 Nghiem P, Ollick T, Gardner P, Schulman H. Interleukin-2 transcriptional block by multifunctional Ca2+/calmodulin kinase. Nature. 371: 347-50. PMID 8090206 DOI: 10.1038/371347a0  0.575
1994 Schuman EM, Meffert MK, Schulman H, Madison DV. An ADP-ribosyltransferase as a potential target for nitric oxide action in hippocampal long-term potentiation. Proceedings of the National Academy of Sciences of the United States of America. 91: 11958-62. PMID 7991564 DOI: 10.1073/Pnas.91.25.11958  0.757
1994 Anderson ME, Braun AP, Schulman H, Premack BA. Multifunctional Ca2+/calmodulin-dependent protein kinase mediates Ca(2+)-induced enhancement of the L-type Ca2+ current in rabbit ventricular myocytes. Circulation Research. 75: 854-61. PMID 7923631 DOI: 10.1161/01.RES.75.5.854  0.526
1994 Meffert MK, Premack BA, Schulman H. Nitric oxide stimulates Ca(2+)-independent synaptic vesicle release. Neuron. 12: 1235-44. PMID 7912090 DOI: 10.1016/0896-6273(94)90440-5  0.73
1994 Chiang LW, Schweizer FE, Tsien RW, Schulman H. Nitric oxide synthase expression in single hippocampal neurons. Brain Research. Molecular Brain Research. 27: 183-8. PMID 7533235 DOI: 10.1016/0169-328X(94)90202-X  0.374
1994 Edman CF, George SE, Means AR, Schulman H, Yaswen P. Selective activation and inhibition of calmodulin-dependent enzymes by a calmodulin-like protein found in human epithelial cells. European Journal of Biochemistry / Febs. 226: 725-30. PMID 7528142 DOI: 10.1111/J.1432-1033.1994.Tb20101.X  0.495
1994 Meffert MK, Haley JE, Schuman EM, Schulman H, Madison DV. Inhibition of hippocampal heme oxygenase, nitric oxide synthase, and long-term potentiation by metalloporphyrins. Neuron. 13: 1225-33. PMID 7524564 DOI: 10.1016/0896-6273(94)90060-4  0.725
1994 Srinivasan M, Edman CF, Schulman H. Alternative splicing introduces a nuclear localization signal that targets multifunctional CaM kinase to the nucleus. The Journal of Cell Biology. 126: 839-52. PMID 7519621 DOI: 10.1083/jcb.126.4.839  0.485
1994 Michelson S, Schulman H. Cam Kinase : A Model For Its Activation And Dynamics Journal of Theoretical Biology. 171: 281-290. DOI: 10.1006/Jtbi.1994.1231  0.462
1993 Schulman H. The multifunctional Ca2+/calmodulin-dependent protein kinases. Current Opinion in Cell Biology. 5: 247-53. PMID 8507497 DOI: 10.1016/0955-0674(93)90111-3  0.576
1993 Nghiem P, Saati SM, Martens CL, Gardner P, Schulman H. Cloning and analysis of two new isoforms of multifunctional Ca2+/calmodulin-dependent protein kinase. Expression in multiple human tissues. The Journal of Biological Chemistry. 268: 5471-9. PMID 8449910  0.405
1993 Schulman H, Hanson PI. Multifunctional Ca2+/calmodulin-dependent protein kinase. Neurochemical Research. 18: 65-77. PMID 8385278 DOI: 10.1007/BF00966924  0.704
1992 Wagner JA, McDonald TV, Nghiem PT, Lowe AW, Schulman H, Gruenert DC, Stryer L, Gardner P. Antisense oligodeoxynucleotides to the cystic fibrosis transmembrane conductance regulator inhibit cAMP-activated but not calcium-activated chloride currents. Proceedings of the National Academy of Sciences of the United States of America. 89: 6785-9. PMID 1379720 DOI: 10.1073/Pnas.89.15.6785  0.364
1992 MacNicol M, Schulman H. Multiple Ca2+ signaling pathways converge on CaM kinase in PC12 cells. Febs Letters. 304: 237-40. PMID 1377643 DOI: 10.1016/0014-5793(92)80627-S  0.562
1992 Malgaroli A, Malinow R, Schulman H, Tsien RW. Persistent signalling and changes in presynaptic function in long-term potentiation. Ciba Foundation Symposium. 164: 176-91; discussion 1. PMID 1327679  0.468
1992 Hanson PI, Schulman H. Inhibitory autophosphorylation of multifunctional Ca2+/calmodulin-dependent protein kinase analyzed by site-directed mutagenesis. The Journal of Biological Chemistry. 267: 17216-24. PMID 1324926  0.642
1992 Schulman H, Hanson PI, Meyer T. Decoding calcium signals by multifunctional CaM kinase. Cell Calcium. 13: 401-11. PMID 1324121 DOI: 10.1016/0143-4160(92)90053-U  0.695
1992 Hanson PI, Schulman H. Neuronal Ca2+/calmodulin-dependent protein kinases. Annual Review of Biochemistry. 61: 559-601. PMID 1323238 DOI: 10.1146/annurev.bi.61.070192.003015  0.693
1992 MacNicol M, Schulman H. Cross-talk between protein kinase C and multifunctional Ca2+/calmodulin-dependent protein kinase. The Journal of Biological Chemistry. 267: 12197-201. PMID 1318312  0.451
1992 Meyer T, Hanson PI, Stryer L, Schulman H. Calmodulin trapping by calcium-calmodulin-dependent protein kinase. Science (New York, N.Y.). 256: 1199-202. PMID 1317063 DOI: 10.1126/Science.256.5060.1199  0.607
1991 Nishimoto I, Wagner JA, Schulman H, Gardner P. Regulation of Cl- channels by multifunctional CaM kinase. Neuron. 6: 547-55. PMID 1849722 DOI: 10.1016/0896-6273(91)90057-7  0.524
1991 Jefferson AB, Travis SM, Schulman H. Activation of multifunctional Ca2+/calmodulin-dependent protein kinase in GH3 cells. The Journal of Biological Chemistry. 266: 1484-90. PMID 1846356  0.513
1991 Schulman H. Serine/threonine kinases in the nervous system. Current Opinion in Neurobiology. 1: 43-52. PMID 1840405 DOI: 10.1016/0959-4388(91)90009-V  0.511
1991 Gardner P, McDonald T, Nishimoto I, Wagner J, Schumann M, Chen J, Schulman H. Regulation of lymphocyte chloride channels. Advances in Experimental Medicine and Biology. 290: 319-26; discussion 3. PMID 1719768 DOI: 10.1007/978-1-4684-5934-0_30  0.339
1991 Wagner JA, Cozens AL, Schulman H, Gruenert DC, Stryer L, Gardner P. Activation of chloride channels in normal and cystic fibrosis airway epithelial cells by multifunctional calcium/calmodulin-dependent protein kinase. Nature. 349: 793-6. PMID 1705665 DOI: 10.1038/349793a0  0.52
1991 Jefferson AB, Schulman H. Phosphorylation of microtubule-associated protein-2 in GH3 cells. Regulation by cAMP and by calcium. The Journal of Biological Chemistry. 266: 346-54. PMID 1702424  0.427
1991 Ocorr KA, Schulman H. Activation of multifunctional Ca2+/calmodulin-dependent kinase in intact hippocampal slices. Neuron. 6: 907-14. PMID 1647175 DOI: 10.1016/0896-6273(91)90231-N  0.589
1990 Baitinger C, Alderton J, Poenie M, Schulman H, Steinhardt RA. Multifunctional Ca2+/calmodulin-dependent protein kinase is necessary for nuclear envelope breakdown. The Journal of Cell Biology. 111: 1763-73. PMID 2229172 DOI: 10.1083/Jcb.111.5.1763  0.549
1990 MacNicol M, Jefferson AB, Schulman H. Ca2+/calmodulin kinase is activated by the phosphatidylinositol signaling pathway and becomes Ca2(+)-independent in PC12 cells. The Journal of Biological Chemistry. 265: 18055-8. PMID 2211681  0.487
1990 Waldmann R, Hanson PI, Schulman H. Multifunctional Ca2+/calmodulin-dependent protein kinase made Ca2+ independent for functional studies. Biochemistry. 29: 1679-84. PMID 2158811 DOI: 10.1021/bi00459a002  0.677
1989 Hanson PI, Kapiloff MS, Lou LL, Rosenfeld MG, Schulman H. Expression of a multifunctional Ca2+/calmodulin-dependent protein kinase and mutational analysis of its autoregulation. Neuron. 3: 59-70. PMID 2619995 DOI: 10.1016/0896-6273(89)90115-3  0.692
1989 Malinow R, Schulman H, Tsien RW. Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP. Science (New York, N.Y.). 245: 862-6. PMID 2549638 DOI: 10.1126/Science.2549638  0.529
1989 Lou LL, Schulman H. Distinct autophosphorylation sites sequentially produce autonomy and inhibition of the multifunctional Ca2+/calmodulin-dependent protein kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 2020-32. PMID 2542484  0.504
1989 Schulman H, Lou LL. Multifunctional Ca2+/calmodulin-dependent protein kinase: domain structure and regulation. Trends in Biochemical Sciences. 14: 62-6. PMID 2539662 DOI: 10.1016/0968-0004(89)90045-5  0.583
1989 Griffith LC, Schulman H, Tagawa M. In vivo and in vitro phosphorylation of murine lymphocyte differentiation antigen CD5. Biochemical and Biophysical Research Communications. 159: 536-41. PMID 2467669 DOI: 10.1016/0006-291X(89)90026-0  0.683
1988 Scholz WK, Baitinger C, Schulman H, Kelly PT. Developmental changes in Ca2+/calmodulin-dependent protein kinase II in cultures of hippocampal pyramidal neurons and astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 1039-51. PMID 3346714  0.401
1988 Griffith LC, Schulman H. The multifunctional Ca2+/calmodulin-dependent protein kinase mediates Ca2+-dependent phosphorylation of tyrosine hydroxylase. The Journal of Biological Chemistry. 263: 9542-9. PMID 2897967  0.72
1988 Schulman H. The multifunctional Ca2+/calmodulin-dependent protein kinase. Advances in Second Messenger and Phosphoprotein Research. 22: 39-112. PMID 2852025  0.496
1988 Jefferson AB, Schulman H. Sphingosine inhibits calmodulin-dependent enzymes. The Journal of Biological Chemistry. 263: 15241-4. PMID 2844804  0.493
1987 Connelly PA, Sisk RB, Schulman H, Garrison JC. Evidence for the activation of the multifunctional Ca2+/calmodulin-dependent protein kinase in response to hormones that increase intracellular Ca2+. The Journal of Biological Chemistry. 262: 10154-63. PMID 3611057  0.467
1987 Lin CR, Kapiloff MS, Durgerian S, Tatemoto K, Russo AF, Hanson P, Schulman H, Rosenfeld MG. Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 84: 5962-6. PMID 3475713 DOI: 10.1073/PNAS.84.16.5962  0.547
1986 Lou LL, Lloyd SJ, Schulman H. Activation of the multifunctional Ca2+/calmodulin-dependent protein kinase by autophosphorylation: ATP modulates production of an autonomous enzyme. Proceedings of the National Academy of Sciences of the United States of America. 83: 9497-501. PMID 3467320 DOI: 10.1073/Pnas.83.24.9497  0.569
1985 Schulman H, Kuret J, Jefferson AB, Nose PS, Spitzer KH. Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase: broad substrate specificity and multifunctional potential in diverse tissues. Biochemistry. 24: 5320-7. PMID 4074698 DOI: 10.1021/Bi00341A008  0.542
1985 Kuret J, Schulman H. Mechanism of autophosphorylation of the multifunctional Ca2+/calmodulin-dependent protein kinase. The Journal of Biological Chemistry. 260: 6427-33. PMID 3997831  0.495
1985 Nose PS, Griffith LC, Schulman H. Ca2+-dependent phosphorylation of tyrosine hydroxylase in PC12 cells. The Journal of Cell Biology. 101: 1182-90. PMID 2413038 DOI: 10.1083/Jcb.101.4.1182  0.733
1984 Schulman H. Phosphorylation of microtubule-associated proteins by a Ca2+/calmodulin-dependent protein kinase. The Journal of Cell Biology. 99: 11-9. PMID 6736124  0.465
1984 Kuret J, Schulman H. Purification and characterization of a Ca2+/calmodulin-dependent protein kinase from rat brain. Biochemistry. 23: 5495-504. PMID 6509030 DOI: 10.1021/Bi00318A018  0.404
1984 Schulman H. Calcium-dependent protein kinases and neuronal function Trends in Pharmacological Sciences. 5: 188-192. DOI: 10.1016/0165-6147(84)90413-9  0.568
1982 Nosé P, Schulman H. Protein phosphorylation system in bovine brain cytosol dependent on calcium and calmodulin. Biochemical and Biophysical Research Communications. 107: 1082-90. PMID 7138514 DOI: 10.1016/0006-291X(82)90632-5  0.522
1980 Sieghart W, Schulman H, Greengard P. Neuronal localization of Ca2+-dependent protein phosphorylation in brain. Journal of Neurochemistry. 34: 548-53. PMID 7354329 DOI: 10.1111/j.1471-4159.1980.tb11179.x  0.568
1980 Whitlock JP, Augustine R, Schulman H. Calcium-dependent phosphorylation of histone H3 in butyrate-treated HeLa cells. Nature. 287: 74-6. PMID 6251382 DOI: 10.1038/287074a0  0.496
1978 Schulman H, Greengard P. Stimulation of brain membrane protein phosphorylation by calcium and an endogenous heat-stable protein. Nature. 271: 478-9. PMID 628428 DOI: 10.1038/271478a0  0.433
1978 Schulman H, Greengard P. Ca2+-dependent protein phosphorylation system in membranes from various tissues, and its activation by "calcium-dependent regulator". Proceedings of the National Academy of Sciences of the United States of America. 75: 5432-6. PMID 214787 DOI: 10.1073/pnas.75.11.5432  0.66
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