Hwan-Ching Bruce Tai, PhD - Related publications

Affiliations: 
Chemistry National Taiwan University, London, Taipei City, Taiwan 
Area:
Aging
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Puzzo D, Argyrousi EK, Staniszewski A, Zhang H, Calcagno E, Zuccarello E, Acquarone E, Fà M, Li Puma DD, Grassi C, D'Adamio L, Kanaan NM, Fraser PE, Arancio O. Tau is not necessary for amyloid-beta-induced synaptic and memory impairments. The Journal of Clinical Investigation. PMID 32544084 DOI: 10.1172/JCI137040   
2020 Nanjundaiah S, Chidambaram H, Chandrashekar M, Chinnathambi S. Role of Microglia in Regulating Cholesterol and Tau Pathology in Alzheimer's Disease. Cellular and Molecular Neurobiology. PMID 32468440 DOI: 10.1007/s10571-020-00883-6   
2020 Harris SS, Wolf F, De Strooper B, Busche MA. Tipping the Scales: Peptide-Dependent Dysregulation of Neural Circuit Dynamics in Alzheimer's Disease. Neuron. PMID 32579881 DOI: 10.1016/j.neuron.2020.06.005   
2020 Sinsky J, Majerova P, Kovac A, Kotlyar M, Jurisica I, Hanes J. Physiological Tau Interactome in Brain and Its Link to Tauopathies. Journal of Proteome Research. 19: 2429-2442. PMID 32357304 DOI: 10.1021/acs.jproteome.0c00137   
2020 Ng PY, Chang IS, Koh RY, Chye SM. Recent advances in tau-directed immunotherapy against Alzheimer's disease: an overview of pre-clinical and clinical development. Metabolic Brain Disease. PMID 32632666 DOI: 10.1007/s11011-020-00591-6   
2020 Gorantla NV, Balaraman E, Chinnathambi S. Cobalt-based metal complexes prevent Repeat Tau aggregation and nontoxic to neuronal cells. International Journal of Biological Macromolecules. 152: 171-179. PMID 32105696 DOI: 10.1016/j.ijbiomac.2020.02.278   
2020 Kaur J, Giri A, Bhattacharya M. The protein-surfactant stoichiometry governs the conformational switching and amyloid nucleation kinetics of tau K18. European Biophysics Journal : Ebj. PMID 32691116 DOI: 10.1007/s00249-020-01447-8   
2020 Keleman A, Wisch JK, Bollinger RM, Grant EA, Benzinger TL, Morris JC, Ances BM, Stark SL. Falls Associate with Neurodegenerative Changes in ATN Framework of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32741815 DOI: 10.3233/JAD-200192   
2020 Dujardin S, Commins C, Lathuiliere A, Beerepoot P, Fernandes AR, Kamath TV, De Los Santos MB, Klickstein N, Corjuc DL, Corjuc BT, Dooley PM, Viode A, Oakley DH, Moore BD, Mullin K, et al. Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease. Nature Medicine. PMID 32572268 DOI: 10.1038/s41591-020-0938-9   
2020 Gu J, Xu W, Jin N, Li L, Zhou Y, Chu D, Gong CX, Iqbal K, Liu F. Truncation of tau selectively facilitates its pathological activities. The Journal of Biological Chemistry. PMID 32737201 DOI: 10.1074/jbc.RA120.012587   
2020 Mamun AA, Uddin MS, Bin Bashar MF, Zaman S, Begum Y, Bulbul IJ, Islam MS, Sarwar MS, Mathew B, Amran MS, Md Ashraf G, Bin-Jumah MN, Mousa SA, Abdel-Daim MM. Molecular Insight into the Therapeutic Promise of Targeting for Alzheimer's Disease. Oxidative Medicine and Cellular Longevity. 2020: 5086250. PMID 32509144 DOI: 10.1155/2020/5086250   
2020 Hirschstein Z, Vanga GR, Wang G, Novakovic ZM, Grasso P. MA-[D-Leu-4]-OB3, a small molecule synthetic peptide leptin mimetic, improves episodic memory, and reduces serum levels of tumor necrosis factor-alpha and neurodegeneration in mouse models of Type 1 and Type 2 Diabetes Mellitus. Biochimica Et Biophysica Acta. General Subjects. 129697. PMID 32738275 DOI: 10.1016/j.bbagen.2020.129697   
2020 Buchanan H, Mackay M, Palmer K, Tothová K, Katsur M, Platt B, Koss DJ. Synaptic Loss, ER Stress and Neuro-Inflammation Emerge Late in the Lateral Temporal Cortex and Associate with Progressive Tau Pathology in Alzheimer's Disease. Molecular Neurobiology. PMID 32514860 DOI: 10.1007/s12035-020-01950-1   
2020 Katsikoudi A, Ficulle E, Cavallini A, Sharman G, Guyot A, Zagnoni M, Eastwood BJ, Hutton M, Bose S. Quantitative propagation of assembled human Tau from Alzheimer's disease brain in microfluidic neuronal cultures. The Journal of Biological Chemistry. PMID 32699110 DOI: 10.1074/jbc.RA120.013325   
2020 Ittner A, Asih PR, Tan ARP, Prikas E, Bertz J, Stefanoska K, Lin Y, Volkerling AM, Ke YD, Delerue F, Ittner LM. Reduction of advanced tau-mediated memory deficits by the MAP kinase p38γ. Acta Neuropathologica. PMID 32725265 DOI: 10.1007/s00401-020-02191-1   
2020 Kaniyappan S, Tepper K, Biernat J, Chandupatla RR, Hübschmann S, Irsen S, Bicher S, Klatt C, Mandelkow EM, Mandelkow E. FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments. Molecular Neurodegeneration. 15: 39. PMID 32677995 DOI: 10.1186/s13024-020-00389-1   
2020 Khoury R, Grossberg GT. Deciphering Alzheimer's disease: predicting new therapeutic strategies via improved understanding of biology and pathogenesis. Expert Opinion On Therapeutic Targets. 1-10. PMID 32603232 DOI: 10.1080/14728222.2020.1790530   
2020 Li D, Zhang J, Li X, Chen Y, Yu F, Liu Q. Insights into lncRNAs in Alzheimer's Disease Mechanisms. Rna Biology. PMID 32605500 DOI: 10.1080/15476286.2020.1788848   
2020 Pomeshchik Y, Klementieva O, Gil J, Martinsson I, Hansen MG, de Vries T, Sancho-Balsells A, Russ K, Savchenko E, Collin A, Vaz AR, Bagnoli S, Nacmias B, Rampon C, Sorbi S, et al. Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies. Stem Cell Reports. PMID 32589876 DOI: 10.1016/j.stemcr.2020.06.001   
2020 Xia Y, Prokop S, Gorion KM, Kim JD, Sorrentino ZA, Bell BM, Manaois AN, Chakrabarty P, Davies P, Giasson BI. Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer's disease and other tauopathies. Acta Neuropathologica Communications. 8: 88. PMID 32571418 DOI: 10.1186/s40478-020-00967-w   
2020 Khalaf NEA, El Banna FM, Youssef MY, Mosaad YM, Daba MY, Ashour RH. Clopidogrel combats neuroinflammation and enhances learning behavior and memory in a rat model of Alzheimer's disease. Pharmacology, Biochemistry, and Behavior. 172956. PMID 32474163 DOI: 10.1016/j.pbb.2020.172956   
2020 Iqbal UH, Zeng E, Pasinetti GM. The Use of Antimicrobial and Antiviral Drugs in Alzheimer's Disease. International Journal of Molecular Sciences. 21. PMID 32664669 DOI: 10.3390/ijms21144920   
2020 Singh M, Singh SP, Dubey PK, Rachana R, Mani S, Yadav D, Agarwal M, Agarwal S, Agarwal V, Kaur H. Advent of Proteomic Tools For Diagnostic Biomarker Analysis in Alzheimer's Disease. Current Protein & Peptide Science. PMID 32538723 DOI: 10.2174/1389203721666200615173213   
2020 Paraskevaidi M, Allsop D, Karim S, Martin FL, Crean S. Diagnostic Biomarkers for Alzheimer's Disease Using Non-Invasive Specimens. Journal of Clinical Medicine. 9. PMID 32492907 DOI: 10.3390/jcm9061673   
2020 Cousins KAQ, Irwin DJ, Wolk DA, Lee EB, Shaw LMJ, Trojanowski JQ, Da Re F, Gibbons GS, Grossman M, Phillips JS. ATN status in amnestic and non-amnestic Alzheimer's disease and frontotemporal lobar degeneration. Brain : a Journal of Neurology. PMID 32666090 DOI: 10.1093/brain/awaa165   
2020 Mukherjee J, Liang C, Patel KK, Lam PQ, Mondal R. Development and Evaluation of [ I]IPPI for Tau Imaging in Post-Mortem Human Alzheimer's Disease Brain. Synapse (New York, N.Y.). e22183. PMID 32722889 DOI: 10.1002/syn.22183   
2020 Pollack SJ, Trigg J, Khanom T, Biasetti L, Marshall KE, Al-Hilaly YK, Rickard JE, Harrington CR, Wischik CM, Serpell LC. Paired Helical Filament Forming Region of Tau (297-391) Influences Endogenous Tau Protein and Accumulates in Acidic Compartments in Human Neuronal Cells. Journal of Molecular Biology. PMID 32681841 DOI: 10.1016/j.jmb.2020.05.027   
2020 Francistiová L, Bianchi C, Di Lauro C, Sebastián-Serrano Á, de Diego-García L, Kobolák J, Dinnyés A, Díaz-Hernández M. The Role of P2X7 Receptor in Alzheimer's Disease. Frontiers in Molecular Neuroscience. 13: 94. PMID 32581707 DOI: 10.3389/fnmol.2020.00094   
2020 Guo T, Zhang D, Zeng Y, Huang TY, Xu H, Zhao Y. Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer's disease. Molecular Neurodegeneration. 15: 40. PMID 32677986 DOI: 10.1186/s13024-020-00391-7   
2020 Nam E, Lee YB, Moon C, Chang KA. Serum Tau Proteins as Potential Biomarkers for the Assessment of Alzheimer's Disease Progression. International Journal of Molecular Sciences. 21. PMID 32679907 DOI: 10.3390/ijms21145007   
2020 Wander CM, Tseng JH, Song S, Al Housseiny HA, Tart DS, Ajit A, Ian Shih YY, Lobrovich R, Song J, Meeker RB, Irwin DJ, Cohen TJ. The Accumulation of Tau-Immunoreactive Hippocampal Granules and Corpora Amylacea Implicates Reactive Glia in Tau Pathogenesis during Aging. Iscience. 23: 101255. PMID 32585593 DOI: 10.1016/j.isci.2020.101255   
2020 Liang Y, Raven F, Ward JF, Zhen S, Zhang S, Sun H, Miller SJ, Choi SH, Tanzi RE, Zhang C. Upregulation of Alzheimer's Disease Amyloid-β Protein Precursor in Astrocytes Both in vitro and in vivo. Journal of Alzheimer's Disease : Jad. PMID 32597805 DOI: 10.3233/JAD-200128   
2020 Wang H, Dey KK, Chen PC, Li Y, Niu M, Cho JH, Wang X, Bai B, Jiao Y, Chepyala SR, Haroutunian V, Zhang B, Beach TG, Peng J. Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer's disease. Molecular Neurodegeneration. 15: 43. PMID 32711556 DOI: 10.1186/s13024-020-00384-6   
2020 Hsu JL, Lin KJ, Hsiao IT, Huang KL, Liu CH, Wu HC, Weng YC, Huang CY, Chang CC, Yen TC, Higuchi M, Jang MK, Huang CC. The Imaging Features and Clinical Associations of a Novel Tau PET Tracer-18F-APN1607 in Alzheimer Disease. Clinical Nuclear Medicine. PMID 32701794 DOI: 10.1097/RLU.0000000000003164   
2020 Simrén J, Ashton NJ, Blennow K, Zetterberg H. An update on fluid biomarkers for neurodegenerative diseases: recent success and challenges ahead. Current Opinion in Neurobiology. 61: 29-39. PMID 31838254 DOI: 10.1016/j.conb.2019.11.019   
2020 Zhou M, Haque RU, Dammer EB, Duong DM, Ping L, Johnson ECB, Lah JJ, Levey AI, Seyfried NT. Targeted mass spectrometry to quantify brain-derived cerebrospinal fluid biomarkers in Alzheimer's disease. Clinical Proteomics. 17: 19. PMID 32514259 DOI: 10.1186/s12014-020-09285-8   
2020 Shin SJ, Park YH, Jeon SG, Kim S, Nam Y, Oh SM, Lee YY, Moon M. Red Ginseng Inhibits Tau Aggregation and Promotes Tau Dissociation . Oxidative Medicine and Cellular Longevity. 2020: 7829842. PMID 32685100 DOI: 10.1155/2020/7829842   
2020 Zhang X, . Higher Plasma APOC-III Was Associated with a Slower Reduction of β-Amyloid Levels in Cerebrospinal Fluid Among Older Individuals Without Dementia. Neuropsychiatric Disease and Treatment. 16: 1139-1144. PMID 32440128 DOI: 10.2147/NDT.S238985   
2020 Hammond TC, Xing X, Wang C, Ma D, Nho K, Crane PK, Elahi F, Ziegler DA, Liang G, Cheng Q, Yanckello LM, Jacobs N, Lin AL. β-amyloid and tau drive early Alzheimer's disease decline while glucose hypometabolism drives late decline. Communications Biology. 3: 352. PMID 32632135 DOI: 10.1038/s42003-020-1079-x   
2020 Rafii MS. Alzheimer's Disease in Down Syndrome: Progress in the Design and Conduct of Drug Prevention Trials. Cns Drugs. PMID 32506291 DOI: 10.1007/s40263-020-00740-6   
2020 Sharda N, Pengo T, Wang Z, Kandimalla KK. Amyloid-β Peptides Disrupt Interactions Between VAMP-2 and SNAP-25 in Neuronal Cells as Determined by FRET/FLIM. Journal of Alzheimer's Disease : Jad. PMID 32675412 DOI: 10.3233/JAD-200065   
2020 Bhute S, Sarmah D, Datta A, Rane P, Shard A, Goswami A, Borah A, Kalia K, Dave KR, Bhattacharya P. Molecular Pathogenesis and Interventional Strategies for Alzheimer's Disease: Promises and Pitfalls. Acs Pharmacology & Translational Science. 3: 472-488. PMID 32566913 DOI: 10.1021/acsptsci.9b00104   
2020 Hammes J, Bischof GN, Bohn KP, Onur O, Schneider A, Fliessbach K, Hoenig MC, Jessen F, Neumaier B, Drzezga AE, van Eimeren T. One stop shop: Flortaucipir PET differentiates amyloid positive and negative forms of neurodegenerative diseases. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 32620704 DOI: 10.2967/jnumed.120.244061   
2020 Uddin MS, Kabir MT, Al Mamun A, Behl T, Mansouri RA, Aloqbi AA, Perveen A, Hafeez A, Ashraf GM. Exploring Potential of Alkaloidal Phytochemicals Targeting Neuroinflammatory Signaling of Alzheimer's Disease. Current Pharmaceutical Design. PMID 32473620 DOI: 10.2174/1381612826666200531151004   
2020 Hernandes-Alejandro M, Montaño S, Harrington CR, Wischik CM, Salas-Casas A, Cortes-Reynosa P, Pérez Salazar E, Cazares-Apatiga J, Apatiga-Perez R, Ontiveros Torres MÁ, Perry G, Pacheco-Herrero M, Luna-Muñoz J. Analysis of the Relationship Between Metalloprotease-9 and Tau Protein in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32538846 DOI: 10.3233/JAD-200146   
2020 Jang JW, Kim Y, Kim S, Park SW, Kwon SO, Park YH, Lim JS, Youn YC, Hun Kim S, Kim S, . Dynamic association between AT(N) profile and cognition mediated by cortical thickness in Alzheimer's continuum. Neuroimage. Clinical. 27: 102282. PMID 32590333 DOI: 10.1016/j.nicl.2020.102282   
2020 Vasanthakumar A, Davis JW, Idler K, Waring JF, Asque E, Riley-Gillis B, Grosskurth S, Srivastava G, Kim S, Nho K, Nudelman KNH, Faber K, Sun Y, Foroud TM, Estrada K, ... , et al. Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease. Clinical Epigenetics. 12: 84. PMID 32539856 DOI: 10.1186/s13148-020-00864-y   
2020 Vaswani PA, Olsen AL. Immunotherapy in progressive supranuclear palsy. Current Opinion in Neurology. PMID 32520801 DOI: 10.1097/WCO.0000000000000836   
2020 Vaswani PA, Olsen AL. Immunotherapy in progressive supranuclear palsy. Current Opinion in Neurology. 33: 527-533. PMID 32657895 DOI: 10.1097/WCO.0000000000000836   
2020 Xie Z, Wu H, Zhao J. Multifunctional roles of zinc in Alzheimer's disease. Neurotoxicology. PMID 32717200 DOI: 10.1016/j.neuro.2020.07.003