Willam F. Morgan - Publications

Affiliations: 
Biochemistry University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Radiology, Biochemistry
Website:
https://www.emgs-us.org/page/william-f-morgan

86 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Baulch JE, Aypar U, Waters KM, Yang AJ, Morgan WF. Genetic and epigenetic changes in chromosomally stable and unstable progeny of irradiated cells. Plos One. 9: e107722. PMID 25251398 DOI: 10.1371/Journal.Pone.0107722  0.53
2011 Aypar U, Morgan WF, Baulch JE. Radiation-induced epigenetic alterations after low and high LET irradiations. Mutation Research. 707: 24-33. PMID 21159317 DOI: 10.1016/J.Mrfmmm.2010.12.003  0.557
2011 Aypar U, Morgan WF, Baulch JE. Radiation-induced genomic instability: are epigenetic mechanisms the missing link? International Journal of Radiation Biology. 87: 179-91. PMID 21039330 DOI: 10.3109/09553002.2010.522686  0.487
2010 Dziegielewski J, Goetz W, Murley JS, Grdina DJ, Morgan WF, Baulch JE. Amifostine metabolite WR-1065 disrupts homologous recombination in mammalian cells. Radiation Research. 173: 175-83. PMID 20095849 DOI: 10.1667/RR1982.1  0.414
2008 Dziegielewski J, Baulch JE, Goetz W, Coleman MC, Spitz DR, Murley JS, Grdina DJ, Morgan WF. WR-1065, the active metabolite of amifostine, mitigates radiation-induced delayed genomic instability. Free Radical Biology & Medicine. 45: 1674-81. PMID 18845240 DOI: 10.1016/J.Freeradbiomed.2008.09.004  0.337
2008 Miller JH, Jin S, Morgan WF, Yang A, Wan Y, Aypar U, Peters JS, Springer DL. Profiling mitochondrial proteins in radiation-induced genome-unstable cell lines with persistent oxidative stress by mass spectrometry. Radiation Research. 169: 700-6. PMID 18494543 DOI: 10.1667/Rr1186.1  0.514
2008 Morales M, Liu Y, Laiakis EC, Morgan WF, Nimer SD, Petrini JH. DNA damage signaling in hematopoietic cells: a role for Mre11 complex repair of topoisomerase lesions. Cancer Research. 68: 2186-93. PMID 18381424 DOI: 10.1158/0008-5472.Can-07-2355  0.346
2007 Huang L, Kim PM, Nickoloff JA, Morgan WF. Targeted and nontargeted effects of low-dose ionizing radiation on delayed genomic instability in human cells. Cancer Research. 67: 1099-104. PMID 17283143 DOI: 10.1158/0008-5472.Can-06-3697  0.314
2007 Morgan WF, Sowa MB. Targeted and non-targeted induction of chromosomal rearrangements after exposure to ionizing radiation Chromosomal Alterations: Methods, Results and Importance in Human Health. 87-98. DOI: 10.1007/978-3-540-71414-9-6  0.378
2004 Sowa Resat MB, Morgan WF. Radiation-induced genomic instability: a role for secreted soluble factors in communicating the radiation response to non-irradiated cells. Journal of Cellular Biochemistry. 92: 1013-9. PMID 15258922 DOI: 10.1002/jcb.20149  0.33
2004 Snyder AR, Morgan WF. Gene expression profiling after irradiation: clues to understanding acute and persistent responses? Cancer Metastasis Reviews. 23: 259-68. PMID 15197327 DOI: 10.1023/B:CANC.0000031765.17886.fa  0.308
2004 Huang L, Grim S, Smith LE, Kim PM, Nickoloff JA, Goloubeva OG, Morgan WF. Ionizing radiation induces delayed hyperrecombination in Mammalian cells. Molecular and Cellular Biology. 24: 5060-8. PMID 15143196 DOI: 10.1128/Mcb.24.11.5060-5068.2004  0.377
2003 Morgan WF. Is there a common mechanism underlying genomic instability, bystander effects and other nontargeted effects of exposure to ionizing radiation? Oncogene. 22: 7094-9. PMID 14557815 DOI: 10.1038/sj.onc.1206992  0.331
2002 Morgan WF. Genomic instability and bystander effects: a paradigm shift in radiation biology? Military Medicine. 167: 44-5. PMID 11873512  0.307
2001 Limoli CL, Kaplan MI, Giedzinski E, Morgan WF. Attenuation of radiation-induced genomic instability by free radical scavengers and cellular proliferation. Free Radical Biology & Medicine. 31: 10-9. PMID 11425485 DOI: 10.1016/S0891-5849(01)00542-1  0.447
2001 Limoli CL, Corcoran JJ, Jordan R, Morgan WF, Schwartz JL. A role for chromosomal instability in the development of and selection for radioresistant cell variants. British Journal of Cancer. 84: 489-92. PMID 11207043 DOI: 10.1054/bjoc.2000.1604  0.352
2000 Limoli CL, Giedzinski E, Morgan WF, Cleaver JE. Polymerase eta deficiency in the xeroderma pigmentosum variant uncovers an overlap between the S phase checkpoint and double-strand break repair. Proceedings of the National Academy of Sciences of the United States of America. 97: 7939-46. PMID 10859352 DOI: 10.1073/Pnas.130182897  0.415
1999 Carney JP, Morgan WF. Induction of DNA double-strand breaks by electroporation of restriction enzymes into mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 113: 465-71. PMID 10443443 DOI: 10.1385/1-59259-675-4:465  0.373
1998 Ponnaiya B, Limoli CL, Corcoran J, Kaplan MI, Hartmann A, Morgan WF. The evolution of chromosomal instability in Chinese hamster cells: a changing picture? International Journal of Radiation Biology. 74: 765-70. PMID 9881722  0.305
1998 Kaplan MI, Morgan WF. The nucleus is the target for radiation-induced chromosomal instability. Radiation Research. 150: 382-90. PMID 9768851 DOI: 10.2307/3579656  0.376
1998 Morgan WF, Corcoran J, Hartmann A, Kaplan MI, Limoli CL, Ponnaiya B. DNA double-strand breaks, chromosomal rearrangements, and genomic instability. Mutation Research. 404: 125-8. PMID 9729329 DOI: 10.1016/S0027-5107(98)00104-3  0.405
1998 Limoli CL, Hartmann A, Shephard L, Yang CR, Boothman DA, Bartholomew J, Morgan WF. Apoptosis, reproductive failure, and oxidative stress in Chinese hamster ovary cells with compromised genomic integrity. Cancer Research. 58: 3712-8. PMID 9721883  0.364
1998 Islas L, Fairley CF, Morgan WF. DNA synthesis on discontinuous templates by human DNA polymerases: implications for non-homologous DNA recombination. Nucleic Acids Research. 26: 3729-38. PMID 9685489 DOI: 10.1093/nar/26.16.3729  0.331
1998 King J, Fairley C, Morgan W. The joining of blunt DNA ends to 3'-protruding single strands in Escherichia coli. Nucleic Acids Research. 26: 1749-54. PMID 9512548 DOI: 10.1093/nar/26.7.1749  0.305
1998 Limoli CL, Day JP, Ward JF, Morgan WF. Induction of chromosome aberrations and delayed genomic instability by photochemical processes. Photochemistry and Photobiology. 67: 233-8. PMID 9487801  0.411
1997 Limoli CL, Kaplan MI, Phillips JW, Adair GM, Morgan WF. Differential induction of chromosomal instability by DNA strand-breaking agents. Cancer Research. 57: 4048-56. PMID 9307292  0.346
1996 Morgan WF, Day JP, Kaplan MI, McGhee EM, Limoli CL. Genomic instability induced by ionizing radiation. Radiation Research. 146: 247-58. PMID 8752302  0.314
1996 King JS, Fairley CF, Morgan WF. DNA end joining by the Klenow fragment of DNA polymerase I. The Journal of Biological Chemistry. 271: 20450-7. PMID 8702784 DOI: 10.1074/jbc.271.34.20450  0.307
1995 Morgan WF, Murnane JP. A role for genomic instability in cellular radioresistance? Cancer and Metastasis Reviews. 14: 49-58. PMID 7606821 DOI: 10.1007/BF00690211  0.305
1994 Phillips JW, Morgan WF. Illegitimate recombination induced by DNA double-strand breaks in a mammalian chromosome Molecular and Cellular Biology. 14: 5794-5803. PMID 8065314  0.367
1993 King JS, Valcarcel ER, Rufer JT, Phillips JW, Morgan WF. Noncomplementary DNA double-strand-break rejoining in bacterial and human cells. Nucleic Acids Research. 21: 1055-9. PMID 8464692 DOI: 10.1093/nar/21.5.1055  0.367
1993 Marder BA, Morgan WF. Delayed chromosomal instability induced by DNA damage Molecular and Cellular Biology. 13: 6667-6677. PMID 8413263  0.334
1993 Phillips JW, Morgan WF. DNA double‐strand breaks in mutagenesis Environmental and Molecular Mutagenesis. 22: 214-217. PMID 8223501 DOI: 10.1002/em.2850220406  0.316
1993 Lutze LH, Cleaver JE, Morgan WF, Winegar RA. Mechanisms involved in rejoining DNA double-strand breaks induced by ionizing radiation and restriction enzymes Mutation Research/Genetic Toxicology. 299: 225-232. PMID 7683090 DOI: 10.1016/0165-1218(93)90099-Y  0.39
1993 Yates BL, Morgan WF. Nonhomologous DNA end rejoining in chromosomal aberration formation Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 285: 53-60. PMID 7678133 DOI: 10.1016/0027-5107(93)90051-G  0.399
1992 Yates BL, Valcarcel ER, Morgan WF. Restriction enzyme-induced DNA double-strand breaks as a model system for cellular responses to DNA damage International Journal of Radiation Oncology, Biology, Physics. 23: 993-998. PMID 1639657 DOI: 10.1016/0360-3016(92)90904-V  0.417
1992 Sachs RK, Yates BL, Tarver J, Morgan WF. Modelling the formation of polycentric chromosome aberrations. International Journal of Radiation Biology. 62: 449-60. PMID 1357058 DOI: 10.1080/09553009214552331  0.326
1992 Rufer JT, Morgan WF. Potentiation of DNA damage by inhibition of poly(ADP-ribosyl)ation: A test of the hypothesis for random nuclease action Experimental Cell Research. 200: 506-512. PMID 1349287 DOI: 10.1016/0014-4827(92)90202-J  0.38
1992 Winegar RA, Lutze LH, Rufer JT, Morgan WF. Spectrum of mutations produced by specific types of restriction enzyme-induced double-strand breaks Mutagenesis. 7: 439-445. PMID 1335541 DOI: 10.1093/mutage/7.6.439  0.308
1991 Borek C, Ong A, Morgan WF, Cleaver JE. Morphological transformation of 10T1/2 mouse embryo cells can be initiated by DNA double-strand breaks alone. Molecular Carcinogenesis. 4: 243-7. PMID 2064728 DOI: 10.1002/Mc.2940040311  0.363
1991 Hai Won Chung, Phillips JW, Winegar RA, Preston RJ, Morgan WF. Modulation of restriction enzyme-induced damage by chemicals that interfere with cellular responses to DNA damage: A cytogenetic and pulsed-field gel analysis Radiation Research. 125: 107-113. PMID 1898780  0.409
1991 Cortés F, Morgan WF, Varcarcel ER, Cleaver JE, Wolff S. Both cross-links and monoadducts induced in DNA by psoralens can lead to sister chromatid exchange formation Experimental Cell Research. 196: 127-130. PMID 1879466 DOI: 10.1016/0014-4827(91)90464-6  0.656
1991 Morgan WF, Yates BL, Rufer JT, Columna EA, Valcarcel ER, Phillips JW. Chromosomal aberration induction in CHO cells by combined exposure to restriction enzymes and x-rays International Journal of Radiation Biology. 60: 627-634. PMID 1680143 DOI: 10.1080/09553009114552451  0.337
1991 Ager DD, Phillips JW, Columna EA, Winegar RA, Morgan WF. Analysis of restriction enzyme-induced DNA double-strand breaks in Chinese hamster ovary cells by pulsed-field gel electrophoresis: Implications for chromosome damage Radiation Research. 128: 150-156. PMID 1658845  0.394
1991 Morgan WF, Valcarcel ER, Columna EA, Winegar RA, Yates BL. Induction of chromosome damage by restriction enzymes during mitosis Radiation Research. 127: 101-106. PMID 1648753  0.398
1991 Cleaver JE, Morgan WF. Poly(ADP-ribose)polymerase: A perplexing participant in cellular responses to DNA breakage Mutation Research - Reviews in Mutation Research. 257: 1-18. DOI: 10.1016/0165-1110(91)90016-O  0.411
1990 Morgan WF, Ager D, Chung HW, Ortiz T, Phillips JW, Winegar RA. The cytogenetic effects of restriction endonucleases following their introduction into cells by electroporation Progress in Clinical and Biological Research. 340: 355-361. PMID 2168049  0.37
1990 Hahn P, Nevaldine B, Morgan WF. X-ray induction of methotrexate resistance due to dhfr gene amplification Somatic Cell and Molecular Genetics. 16: 413-423. PMID 2122527 DOI: 10.1007/BF01233191  0.387
1990 Winegar RA, Phillips JW, Lutze LH, Morgan WF. Chromosome aberration induction in Chinese hamster ovary cells by restriction enzymes with different methylation sensitivity Somatic Cell and Molecular Genetics. 16: 251-256. PMID 1694308 DOI: 10.1007/BF01233361  0.461
1989 Winegar RA, Catherine Land M, Morgan WF. Increased chromosomal radiosensitivity of a Chinese hamster ovary cell line that inducibly expresses the Eco RI restriction endonuclease Biochemical and Biophysical Research Communications. 160: 1079-1084. PMID 2730638 DOI: 10.1016/S0006-291X(89)80113-5  0.454
1989 Morgan WF, Chung HW, Phillips JW, Winegar RA. Restriction endonucleases do not induce sister-chromatid exchanges in Chinese hamster ovary cells Mutation Research Letters. 226: 203-210. PMID 2546073 DOI: 10.1016/0165-7992(89)90021-3  0.44
1989 Winegar RA, Phillips JW, Youngblom JH, Morgan WF. Cell electroporation is a highly efficient method for introducing restriction endonucleases into cells Mutation Research Letters. 225: 49-53. PMID 2536473 DOI: 10.1016/0165-7992(89)90032-8  0.427
1989 Jostes R, Reese JA, Cleaver JE, Molero M, Morgan WF. Quiescent human lymphocytes do not contain DNA strand breaks detectable by alkaline elution. Experimental Cell Research. 182: 513-20. PMID 2524401 DOI: 10.1016/0014-4827(89)90254-1  0.356
1988 Cleaver JE, Cortés F, Karentz D, Lutze LH, Morgan WF, Player AN, Vuksanovic L, Mitchell DL. THE RELATIVE BIOLOGICAL IMPORTANCE OF CYCLOBUTANE AND(6–4) PYRIMIDINE‐PYRIMIDONE DIMER PHOTOPRODUCTS IN HUMAN CELLS: EVIDENCE FROM A XERODERMA PIGMENTOSUM REVERTANT Photochemistry and Photobiology. 48: 41-49. PMID 3217441 DOI: 10.1111/J.1751-1097.1988.Tb02784.X  0.409
1988 Mackey MA, Morgan WF, Dewey WC. Nuclear fragmentation and premature chromosome condensation induced by heat shock in S-phase Chinese hamster ovary cells. Cancer Research. 48: 6478-83. PMID 3180064  0.355
1988 Morgan WF, Fero ML, Land MC, Winegar RA. Inducible expression and cytogenetic effects of the EcoRI restriction endonuclease in Chinese hamster ovary cells Molecular and Cellular Biology. 8: 4204-4211. PMID 3054512  0.309
1987 Cortés F, Morgan WF, Wolff S. Effect of exogenous thymidine on sister-chromatid exchange frequency in Chinese hamster ovary cells with bromodeoxyuridine- and chlorodeoxyuridine-substituted chromosomes Mutation Research Letters. 192: 277-282. PMID 3683442 DOI: 10.1016/0165-7992(87)90069-8  0.666
1987 Cleaver JE, Morgan WF. Differences in the stimulation of repair replication by 3-aminobenzamide in lymphoblastoid cells damaged by methylmethanesulfonate or ultraviolet light Carcinogenesis. 8: 1291-1294. PMID 3621467 DOI: 10.1093/Carcin/8.9.1291  0.423
1987 Cleaver JE, Cortés F, Lutze LH, Morgan WF, Player AN, Mitchell DL. Unique DNA repair properties of a xeroderma pigmentosum revertant Molecular and Cellular Biology. 7: 3353-3357. PMID 3118197 DOI: 10.1128/Mcb.7.9.3353  0.311
1987 Cleaver JE, Morgan WF. 3-Aminobenzamide, an inhibitor of poly(ADP-ribose) polymerase, is a stimulator, not an inhibitor, of DNA repair Experimental Cell Research. 172: 258-264. PMID 3115799 DOI: 10.1016/0014-4827(87)90385-5  0.37
1987 Wiencke JK, Morgan WF. Cell cycle-dependent potentiation of X-ray-induced chromosomal aberrations by 3-Aminobenzamide Biochemical and Biophysical Research Communications. 143: 372-376. PMID 3103620 DOI: 10.1016/0006-291X(87)90675-9  0.38
1986 Morgan WF, Bodycote J, Fero ML, Hahn PJ, Kapp LN, Pantelias GE, Painter RB. A cytogenetic investigation of DNA rereplication after hydroxyurea treatment: implications for gene amplification. Chromosoma. 93: 191-6. PMID 3948597 DOI: 10.1007/Bf00292737  0.409
1986 Hahn P, Kapp LN, Painter RB, Morgan WF. Chromosomal Changes without DNA Overproduction in Hydroxyurea-treated Mammalian Cells: Implications for Gene Amplification Cancer Research. 46: 4607-4612. PMID 3731112  0.419
1986 Morgan WF, Doida Y, Fero ML, Guo XC, Shadley JD. Potentiation of sister chromatid exchange by 3-aminobenzamide is not modulated by topoisomerases or proteases. Environmental Mutagenesis. 8: 487-93. PMID 3015582 DOI: 10.1002/em.2860080402  0.404
1986 Xi‐Cang G, Morgan WF, Cleaver JE. HOECHST 33258 DYE GENERATES DNA‐PROTEIN CROSS‐LINKS DURING ULTRAVIOLET LIGHT‐INDUCED PHOTOLYSIS OF BROMODEOXYURIDINE IN REPLICATED AND REPAIRED DNA Photochemistry and Photobiology. 44: 131-136. PMID 2430309 DOI: 10.1111/J.1751-1097.1986.Tb03576.X  0.336
1985 Schwartz JL, Morgan WF, Weichselbaum RR. Different efficiencies of interaction between 3-aminobenzamide and various monofunctional alkylating agents in the induction of sister chromatid exchanges Carcinogenesis. 6: 699-704. PMID 4006055 DOI: 10.1093/carcin/6.5.699  0.429
1985 Schwartz JL, Morgan WF, Brown-Lindquist P, Afzal V, Weichselbaum RR, Wolff S. Comutagenic Effects of 3-Aminobenzamide in Chinese Hamster Ovary Cells Cancer Research. 45: 1556-1559. PMID 3978624  0.382
1985 Park SD, Seong NH, Morgan WF, Cleaver JE. Single-strand breaks in DNA of hamster and human cells exposed to methyl methanesulfonate and ultraviolet light. Chemico-Biological Interactions. 52: 255-63. PMID 3971468 DOI: 10.1016/0009-2797(85)90021-3  0.355
1985 Bodell WJ, Morgan WF, Rasmussen J, Williams ME, Deen DF. Potentiation of 1,3-BIS(2-chloroethyl)-1-nitrosourea (BCNU)-induced cytotoxicity in 9L cells by pretreatment with 6-thioguanine Biochemical Pharmacology. 34: 515-520. PMID 3970721 DOI: 10.1016/0006-2952(85)90182-0  0.444
1985 Cleaver JE, Borek C, Milam K, Morgan WF. The role of poly(ADP-ribose) synthesis in toxicity and repair of DNA damage. Pharmacology & Therapeutics. 31: 269-93. PMID 3939630 DOI: 10.1016/0163-7258(85)90026-9  0.329
1985 Cleaver JE, Morgan WF. Poly(ADP-ribose) synthesis is involved in the toxic effects of alkylating agents but does not regulate DNA repair Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 150: 69-76. PMID 3923344 DOI: 10.1016/0027-5107(85)90102-2  0.402
1985 Cleaver JE, Milam KM, Morgan WF. Do inhibitor studies demonstrate a role for poly(ADP-ribose) in DNA repair? Radiation Research. 101: 16-28. PMID 3918329  0.395
1985 Morgan WF, Djordjevic MC, Jostes RF, Pantelias GE. Delayed repair of DNA single-Strand breaks does not increase cytogenetic damage International Journal of Radiation Biology. 48: 711-721. PMID 3877012 DOI: 10.1080/09553008514551811  0.454
1985 Bianchi NO, Morgan WF, Cleaver JE. Relationship of ultraviolet light-induced DNA-protein cross-linkage to chromatin structure Experimental Cell Research. 156: 405-418. PMID 2981693 DOI: 10.1016/0014-4827(85)90547-6  0.336
1984 Schwartz JL, Morgan WF, Wolff S. Reduction of sister chromatid exchange frequency with time after mutagen exposure in Chinese hamster ovary cells in the presence of 3-aminobenzamide Environmental Mutagenesis. 6: 203-210. PMID 6705757 DOI: 10.1002/Em.2860060208  0.653
1984 Borek C, Morgan WF, Ong A, Cleaver JE. Inhibition of malignant transformation in vitro by inhibitors of poly(ADP-ribose) synthesis. Proceedings of the National Academy of Sciences of the United States of America. 81: 243-7. PMID 6582479 DOI: 10.1073/Pnas.81.1.243  0.395
1984 Morgan WF, Wolff S. Effect of 5-bromodeoxyuridine substitution on sister chromatid exchange induction by chemicals Chromosoma. 89: 285-289. PMID 6204821 DOI: 10.1007/Bf00292476  0.666
1984 Morgan WF, Wolff S. Effect of bromodeoxyuridine on induced sister chromatid exchanges Basic Life Sciences. 29: 281-292. PMID 6085262  0.49
1983 Cleaver JE, Bodell WJ, Morgan WF, Zelle B. Differences in the regulation by poly(ADP-ribose) of repair of DNA damage from alkylating agents and ultraviolet light according to cell type Journal of Biological Chemistry. 258: 9059-9068. PMID 6874677  0.433
1983 Schwartz JL, Morgan WF, Kapp LN, Wolff S. Effects of 3-aminobenzamide on DNA synthesis and cell cycle progression in Chinese hamster ovary cells. Experimental Cell Research. 143: 377-82. PMID 6832224 DOI: 10.1016/0014-4827(83)90064-2  0.661
1983 Cleaver JE, Bodell WJ, Borek C, Morgan WF, Schwartz JL. Poly(ADP-ribose): spectator or participant in excision repair of DNA damage. Princess Takamatsu Symposia. 13: 195-207. PMID 6686227  0.312
1983 Morgan WF, Cleaver JE. Effect of 3-aminobenzamide on the rate of ligation during repair of alkylated DNA in human fibroblasts Cancer Research. 43: 3104-3107. PMID 6303576  0.439
1983 Morgan WF, Schwartz JL, Murnane JP, Wolff S. Effect of 3-Aminobenzamide on Sister Chromatid Exchange Frequency in X-Irradiated Cells Radiation Research. 93: 567. DOI: 10.2307/3576035  0.625
1982 Morgan WF, Crossen PE. X irradiation and sister chromatid exchange in cultured human lymphocytes. Environmental Mutagenesis. 2: 149-55. PMID 7327164 DOI: 10.1002/em.2860020207  0.315
1982 Morgan WF, Cleaver JE. 3-Aminobenzamide synergistically increases sister-chromatid exchanges in cells exposed to methyl methanesulfonate but not to ultraviolet light. Mutation Research. 104: 361-6. PMID 6287250 DOI: 10.1016/0165-7992(82)90170-1  0.365
1982 Morgan WF, Crossen PE. A comparison of induced sister chromatid exchange levels in Chinese hamster ovary cells and cultured human lymphocytes. Environmental Mutagenesis. 4: 65-71. PMID 6175512 DOI: 10.1002/em.2860040109  0.424
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