Radhakrishnan Mahadevan - Publications

Affiliations: 
Chemical Engineering and Applied Chemistry University of Toronto, Toronto, ON, Canada 
Area:
Chemical Engineering, Applied Mathematics, System Science Engineering, Biomedical Engineering

113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Manchel A, Mahadevan R, Bataller R, Hoek JB, Vadigepalli R. Genome-Scale Metabolic Modeling Reveals Sequential Dysregulation of Glutathione Metabolism in Livers from Patients with Alcoholic Hepatitis. Metabolites. 12. PMID 36557195 DOI: 10.3390/metabo12121157  0.614
2022 Haddadi K, Ahmed Barghout R, Mahadevan R. KinMod database: a tool for investigating metabolic regulation. Database : the Journal of Biological Databases and Curation. 2022. PMID 36222201 DOI: 10.1093/database/baac081  0.328
2021 Euler C, Mahadevan R. On the Design Principles of Metabolic Flux Sensing. Biophysical Journal. PMID 34951981 DOI: 10.1016/j.bpj.2021.12.022  0.304
2020 Raj K, Venayak N, Mahadevan R. Novel two-stage processes for optimal chemical production in microbes. Metabolic Engineering. PMID 32827703 DOI: 10.1016/j.ymben.2020.08.006  0.34
2020 Raj K, Venayak N, Mahadevan R. Novel two-stage processes for optimal chemical production in microbes. Metabolic Engineering. PMID 32827703 DOI: 10.1016/j.ymben.2020.08.006  0.34
2020 Correia K, Mahadevan R. Pan-Genome-Scale Network Reconstruction: Harnessing Phylogenomics Increases the Quantity and Quality of Metabolic Models. Biotechnology Journal. e1900519. PMID 32744423 DOI: 10.1002/Biot.201900519  0.35
2020 Al-Fahad AJ, Al-Fageeh MB, Kharbatia NM, Sioud S, Mahadevan R. Metabolically engineered recombinant for the production of 2-Deoxy--inosose (2-DOI). Metabolic Engineering Communications. 11: e00134. PMID 32670790 DOI: 10.1016/J.Mec.2020.E00134  0.457
2020 Choudhary R, Mahadevan R. Toward a systematic design of smart probiotics. Current Opinion in Biotechnology. 64: 199-209. PMID 32603961 DOI: 10.1016/J.Copbio.2020.05.003  0.387
2020 Liu Y, Chen J, Crisante D, Jaramillo Lopez JM, Mahadevan R. Dynamic Cell Programming with Quorum Sensing-Controlled CRISPRi Circuit. Acs Synthetic Biology. 9: 1284-1291. PMID 32485106 DOI: 10.1021/Acssynbio.0C00148  0.335
2020 Lieven C, Beber ME, Olivier BG, Bergmann FT, Ataman M, Babaei P, Bartell JA, Blank LM, Chauhan S, Correia K, Diener C, Dräger A, Ebert BE, Edirisinghe JN, Faria JP, ... ... Mahadevan R, et al. Publisher Correction: MEMOTE for standardized genome-scale metabolic model testing. Nature Biotechnology. 38: 504. PMID 32265554 DOI: 10.1038/S41587-020-0477-4  0.348
2020 Lieven C, Beber ME, Olivier BG, Bergmann FT, Ataman M, Babaei P, Bartell JA, Blank LM, Chauhan S, Correia K, Diener C, Dräger A, Ebert BE, Edirisinghe JN, Faria JP, ... ... Mahadevan R, et al. MEMOTE for standardized genome-scale metabolic model testing. Nature Biotechnology. PMID 32123384 DOI: 10.1038/S41587-020-0446-Y  0.359
2019 Kim T, Stogios PJ, Khusnutdinova AN, Nemr K, Skarina T, Flick R, Joo JC, Mahadevan R, Savchenko A, Yakunin AF. Rational engineering of 2-deoxyribose-5-phosphate aldolases for the biosynthesis of ()-1,3-butanediol. The Journal of Biological Chemistry. PMID 31806708 DOI: 10.1074/Jbc.Ra119.011363  0.678
2019 Srinivasan S, Cluett WR, Mahadevan R. A scalable method for parameter identification in kinetic models of metabolism using steady state data. Bioinformatics (Oxford, England). PMID 31197317 DOI: 10.1093/Bioinformatics/Btz445  0.346
2019 Venayak N, Raj K, Jaydeep R, Mahadevan R. Correction to An Optimized Bistable Metabolic Switch to Decouple Phenotypic States during Anaerobic Fermentation. Acs Synthetic Biology. PMID 31181896 DOI: 10.1021/Acssynbio.9B00182  0.392
2019 Venayak N, Raj K, Mahadevan R. Impact framework: A python package for writing data analysis workflows to interpret microbial physiology. Metabolic Engineering Communications. 9: e00089. PMID 31011536 DOI: 10.1016/J.Mec.2019.E00089  0.383
2019 Biz A, Proulx S, Xu Z, Siddartha K, Indrayanti AM, Mahadevan R. Systems biology based metabolic engineering for non-natural chemicals. Biotechnology Advances. PMID 30953683 DOI: 10.1016/J.Biotechadv.2019.04.001  0.496
2019 Wang PH, Correia K, Ho HC, Venayak N, Nemr K, Flick R, Mahadevan R, Edwards EA. An interspecies malate-pyruvate shuttle reconciles redox imbalance in an anaerobic microbial community. The Isme Journal. PMID 30607026 DOI: 10.1038/S41396-018-0333-4  0.748
2019 Kadam K, Euler CK, Mahadevan R. Evaluating the performance of a post-translational dynamic metabolic control system Ifac-Papersonline. 52: 225-230. DOI: 10.1016/J.Ifacol.2019.12.262  0.448
2018 Venayak N, von Kamp A, Klamt S, Mahadevan R. MoVE identifies metabolic valves to switch between phenotypic states. Nature Communications. 9: 5332. PMID 30552335 DOI: 10.1038/S41467-018-07719-4  0.473
2018 Venayak N, Raj K, Jaydeep R, Mahadevan R. An Optimized Bistable Metabolic Switch To Decouple Phenotypic States during Anaerobic Fermentation. Acs Synthetic Biology. PMID 30376634 DOI: 10.1021/Acssynbio.8B00284  0.453
2018 Nemr K, Müller JEN, Joo JC, Gawand P, Choudhary R, Mendonca B, Lu S, Yu X, Yakunin AF, Mahadevan R. Engineering a short, aldolase-based pathway for (R)-1,3-butanediol production in Escherichia coli. Metabolic Engineering. PMID 29753069 DOI: 10.1016/J.Ymben.2018.04.013  0.778
2018 Wang PH, Khusnutdinova AN, Luo F, Xiao J, Nemr K, Flick R, Brown G, Mahadevan R, Edwards EA, Yakunin AF. Biosynthesis and Activity of Prenylated FMN Cofactors. Cell Chemical Biology. PMID 29551348 DOI: 10.1016/J.Chembiol.2018.02.007  0.689
2018 Xu Z, Mahadevan R. Efficient Biochemical Pathway Prediction Using Simulated Annealing Ifac-Papersonline. 51: 56-57. DOI: 10.1016/J.Ifacol.2018.09.041  0.337
2017 Srinivasan S, Cluett WR, Mahadevan R. Model-based Design of Bistable Cell Factories for Metabolic Engineering. Bioinformatics (Oxford, England). PMID 29220508 DOI: 10.1093/Bioinformatics/Btx769  0.463
2017 Klamt S, Mahadevan R, Hädicke O. When do two-stage processes outperform one-stage processes? Biotechnology Journal. PMID 29131522 DOI: 10.1002/Biot.201700539  0.368
2017 Partow S, Hyland PB, Mahadevan R. Synthetic rescue couples NADPH generation to metabolite overproduction in Saccharomyces cerevisiae. Metabolic Engineering. PMID 28803913 DOI: 10.1016/J.Ymben.2017.08.004  0.523
2017 Joo JC, Khusnutdinova AN, Flick R, Kim T, Bornscheuer UT, Yakunin AF, Mahadevan R. Alkene hydrogenation activity of enoate reductases for an environmentally benign biosynthesis of adipic acid. Chemical Science. 8: 1406-1413. PMID 28616142 DOI: 10.1039/C6Sc02842J  0.626
2017 Pandit AV, Srinivasan S, Mahadevan R. Redesigning metabolism based on orthogonality principles. Nature Communications. 8: 15188. PMID 28555623 DOI: 10.1038/Ncomms15188  0.483
2017 Klamt S, Regensburger G, Gerstl MP, Jungreuthmayer C, Schuster S, Mahadevan R, Zanghellini J, Müller S. From elementary flux modes to elementary flux vectors: Metabolic pathway analysis with arbitrary linear flux constraints. Plos Computational Biology. 13: e1005409. PMID 28406903 DOI: 10.1371/Journal.Pcbi.1005409  0.425
2017 Kim T, Flick R, Brunzelle J, Singer A, Evdokimova E, Brown G, Joo JC, Minasov GA, Anderson WF, Mahadevan R, Savchenko A, Yakunin AF. Structural and biochemical studies of novel aldo-keto reductases for the biocatalytic conversion of 3-hydroxybutanal to 1,3-butanediol. Applied and Environmental Microbiology. PMID 28130301 DOI: 10.1128/Aem.03172-16  0.652
2016 Wang PH, Tang S, Nemr K, Flick R, Yan J, Mahadevan R, F Yakunin A, Löffler FE, Edwards EA. Refined experimental annotation reveals conserved corrinoid autotrophy in chloroform-respiring Dehalobacter isolates. The Isme Journal. PMID 27898054 DOI: 10.1038/Ismej.2016.158  0.715
2016 Euler CK, Mahadevan R. Protein-Level Control of Metabolism: Design Principles and Prospects from a Representative System Ifac-Papersonline. 49: 165-170. DOI: 10.1016/J.Ifacol.2016.12.120  0.472
2016 Toroghi MK, Cluett WR, Mahadevan R. A Multi-Scale Model of the Whole Human Body based on Dynamic Parsimonious Flux Balance Analysis Ifac-Papersonline. 49: 937-942. DOI: 10.1016/J.Ifacol.2016.07.319  0.398
2015 Rodenhizer D, Gaude E, Cojocari D, Mahadevan R, Frezza C, Wouters BG, McGuigan AP. A three-dimensional engineered tumour for spatial snapshot analysis of cell metabolism and phenotype in hypoxic gradients. Nature Materials. PMID 26595121 DOI: 10.1038/Nmat4482  0.378
2015 Islam MA, Tchigvintsev A, Yim V, Savchenko A, Yakunin AF, Mahadevan R, Edwards EA. Experimental validation of in silico model-predicted isocitrate dehydrogenase and phosphomannose isomerase from Dehalococcoides mccartyi. Microbial Biotechnology. PMID 26374290 DOI: 10.1111/1751-7915.12315  0.358
2015 Srinivasan S, Cluett WR, Mahadevan R. Constructing kinetic models of metabolism at genome-scales: A review. Biotechnology Journal. 10: 1345-59. PMID 26332243 DOI: 10.1002/Biot.201400522  0.378
2015 Klamt S, Mahadevan R. On the feasibility of growth-coupled product synthesis in microbial strains. Metabolic Engineering. 30: 166-78. PMID 26112955 DOI: 10.1016/J.Ymben.2015.05.006  0.418
2015 Gawand P, Said Abukar F, Venayak N, Partow S, Motter AE, Mahadevan R. Sub-optimal phenotypes of double-knockout mutants of Escherichia coli depend on the order of gene deletions. Integrative Biology : Quantitative Biosciences From Nano to Macro. 7: 930-9. PMID 26079398 DOI: 10.1039/C5Ib00096C  0.791
2015 Gold ND, Gowen CM, Lussier FX, Cautha SC, Mahadevan R, Martin VJ. Metabolic engineering of a tyrosine-overproducing yeast platform using targeted metabolomics. Microbial Cell Factories. 14: 73. PMID 26016674 DOI: 10.1186/S12934-015-0252-2  0.472
2015 Islam MA, Zengler K, Edwards EA, Mahadevan R, Stephanopoulos G. Investigating Moorella thermoacetica metabolism with a genome-scale constraint-based metabolic model. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 25994252 DOI: 10.1039/C5Ib00095E  0.621
2015 Mahadevan R, von Kamp A, Klamt S. Genome-scale strain designs based on regulatory minimal cut sets. Bioinformatics (Oxford, England). PMID 25913205 DOI: 10.1093/Bioinformatics/Btv217  0.404
2015 Venayak N, Anesiadis N, Cluett WR, Mahadevan R. Engineering metabolism through dynamic control. Current Opinion in Biotechnology. 34: 142-52. PMID 25616051 DOI: 10.1016/J.Copbio.2014.12.022  0.799
2015 Yang L, Srinivasan S, Mahadevan R, Cluett WR. Characterizing metabolic pathway diversification in the context of perturbation size. Metabolic Engineering. 28: 114-22. PMID 25542850 DOI: 10.1016/J.Ymben.2014.11.013  0.733
2015 Mahadevan R, Doyle FJ. Nonlinear nonsquare control of a continuous bioreactor using flat outputs European Control Conference, Ecc 1999 - Conference Proceedings. 3757-3762.  0.346
2014 Jayasinghe N, Franks A, Nevin KP, Mahadevan R. Metabolic modeling of spatial heterogeneity of biofilms in microbial fuel cells reveals substrate limitations in electrical current generation. Biotechnology Journal. 9: 1350-61. PMID 25113946 DOI: 10.1002/Biot.201400068  0.378
2014 Islam MA, Waller AS, Hug LA, Provart NJ, Edwards EA, Mahadevan R. New insights into Dehalococcoides mccartyi metabolism from a reconstructed metabolic network-based systems-level analysis of D. mccartyi transcriptomes. Plos One. 9: e94808. PMID 24733489 DOI: 10.1371/Journal.Pone.0094808  0.454
2014 Bourdakos N, Marsili E, Mahadevan R. A defined co-culture of Geobacter sulfurreducens and Escherichia coli in a membrane-less microbial fuel cell. Biotechnology and Bioengineering. 111: 709-18. PMID 24155100 DOI: 10.1002/Bit.25137  0.325
2014 Gawand P, Mahadevan R. Engineering Escherichia coli for D-ribose production from glucose-xylose mixtures Industrial Biotechnology. 10: 106-114. DOI: 10.1089/ind.2013.0028  0.779
2013 Salimi F, Mahadevan R. Characterizing metabolic interactions in a clostridial co-culture for consolidated bioprocessing. Bmc Biotechnology. 13: 95. PMID 24188120 DOI: 10.1186/1472-6750-13-95  0.634
2013 Gawand P, Hyland P, Ekins A, Martin VJ, Mahadevan R. Novel approach to engineer strains for simultaneous sugar utilization. Metabolic Engineering. 20: 63-72. PMID 23988492 DOI: 10.1016/J.Ymben.2013.08.003  0.8
2013 Anesiadis N, Kobayashi H, Cluett WR, Mahadevan R. Analysis and design of a genetic circuit for dynamic metabolic engineering. Acs Synthetic Biology. 2: 442-52. PMID 23654263 DOI: 10.1021/Sb300129J  0.8
2013 Gawand P, Yang L, Cluett WR, Mahadevan R. Metabolic model refinement using phenotypic microarray data. Methods in Molecular Biology (Clifton, N.J.). 985: 47-59. PMID 23417798 DOI: 10.1007/978-1-62703-299-5_3  0.787
2013 Zhuang K, Yang L, Cluett WR, Mahadevan R. Dynamic strain scanning optimization: an efficient strain design strategy for balanced yield, titer, and productivity. DySScO strategy for strain design. Bmc Biotechnology. 13: 8. PMID 23388063 DOI: 10.1186/1472-6750-13-8  0.728
2013 Javaherian S, Anesiadis N, Mahadevan R, McGuigan AP. Design principles for generating robust gene expression patterns in dynamic engineered tissues. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 578-89. PMID 23369944 DOI: 10.1039/C3Ib20274G  0.759
2013 Zheng H, Beliavsky A, Tchigvintsev A, Brunzelle JS, Brown G, Flick R, Evdokimova E, Wawrzak Z, Mahadevan R, Anderson WF, Savchenko A, Yakunin AF. Structure and activity of the NAD(P)+-dependent succinate semialdehyde dehydrogenase YneI from Salmonella typhimurium. Proteins. 81: 1031-41. PMID 23229889 DOI: 10.1002/Prot.24227  0.315
2013 Cautha SC, Gowen CM, Lussier FX, Gold ND, Martin VJJ, Mahadevan R. Model-driven design of a Saccharomyces cerevisiae platform strain with improved tyrosine production capabilities Ifac Proceedings Volumes (Ifac-Papersonline). 12: 221-226. DOI: 10.3182/20131216-3-In-2044.00066  0.449
2013 Hyland PB, Mun SLS, Mahadevan R. Prediction of weak acid toxicity in saccharomyces cerevisiae using genome-scale metabolic models Industrial Biotechnology. 9: 229-235. DOI: 10.1089/Ind.2013.0004  0.412
2013 Zhao J, Scheibe TD, Mahadevan R. Model-based analysis of mixed uranium(VI) reduction by biotic and abiotic pathways during in situ bioremediation Chemical Geology. 357: 215-222. DOI: 10.1016/J.Chemgeo.2013.08.037  0.341
2013 Tartakovsky GD, Tartakovsky AM, Scheibe TD, Fang Y, Mahadevan R, Lovley DR. Pore-scale simulation of microbial growth using a genome-scale metabolic model: Implications for Darcy-scale reactive transport Advances in Water Resources. 59: 256-270. DOI: 10.1016/J.Advwatres.2013.05.007  0.343
2012 Mahadevan R, Henson MA. Genome-based Modeling and Design of Metabolic Interactions in Microbial Communities. Computational and Structural Biotechnology Journal. 3: e201210008. PMID 24688668 DOI: 10.5936/Csbj.201210008  0.384
2012 Khazaei T, McGuigan A, Mahadevan R. Ensemble modeling of cancer metabolism. Frontiers in Physiology. 3: 135. PMID 22623918 DOI: 10.3389/Fphys.2012.00135  0.422
2012 Zhuang K, Ma E, Lovley DR, Mahadevan R. The design of long-term effective uranium bioremediation strategy using a community metabolic model. Biotechnology and Bioengineering. 109: 2475-83. PMID 22510989 DOI: 10.1002/Bit.24528  0.337
2012 Facchini PJ, Bohlmann J, Covello PS, De Luca V, Mahadevan R, Page JE, Ro DK, Sensen CW, Storms R, Martin VJ. Synthetic biosystems for the production of high-value plant metabolites. Trends in Biotechnology. 30: 127-31. PMID 22209518 DOI: 10.1016/J.Tibtech.2011.10.001  0.368
2012 Barlett M, Zhuang K, Mahadevan R, Lovley D. Integrative analysis of Geobacter spp. and sulfate-reducing bacteria during uranium bioremediation Biogeosciences. 9: 1033-1040. DOI: 10.5194/Bg-9-1033-2012  0.322
2011 Usher J, Balderas-Hernandez V, Quon P, Gold ND, Martin VJ, Mahadevan R, Baetz K. Chemical and Synthetic Genetic Array Analysis Identifies Genes that Suppress Xylose Utilization and Fermentation in Saccharomyces cerevisiae. G3 (Bethesda, Md.). 1: 247-58. PMID 22384336 DOI: 10.1534/G3.111.000695  0.43
2011 Pandit AV, Mahadevan R. In silico characterization of microbial electrosynthesis for metabolic engineering of biochemicals. Microbial Cell Factories. 10: 76. PMID 21967745 DOI: 10.1186/1475-2859-10-76  0.45
2011 Zhuang K, Vemuri GN, Mahadevan R. Economics of membrane occupancy and respiro-fermentation. Molecular Systems Biology. 7: 500. PMID 21694717 DOI: 10.1038/Msb.2011.34  0.365
2011 Yang L, Cluett WR, Mahadevan R. EMILiO: a fast algorithm for genome-scale strain design. Metabolic Engineering. 13: 272-81. PMID 21414417 DOI: 10.1016/J.Ymben.2011.03.002  0.677
2011 Zhao J, Scheibe TD, Mahadevan R. Model-based analysis of the role of biological, hydrological and geochemical factors affecting uranium bioremediation Biotechnology and Bioengineering. 108: 1537-1548. PMID 21337330 DOI: 10.1002/Bit.23096  0.315
2011 Fang Y, Scheibe TD, Mahadevan R, Garg S, Long PE, Lovley DR. Direct coupling of a genome-scale microbial in silico model and a groundwater reactive transport model. Journal of Contaminant Hydrology. 122: 96-103. PMID 21172725 DOI: 10.1016/J.Jconhyd.2010.11.007  0.399
2011 Mahadevan R, Palsson BØ, Lovley DR. In situ to in silico and back: elucidating the physiology and ecology of Geobacter spp. using genome-scale modelling. Nature Reviews. Microbiology. 9: 39-50. PMID 21132020 DOI: 10.1038/Nrmicro2456  0.421
2011 Zhuang K, Izallalen M, Mouser P, Richter H, Risso C, Mahadevan R, Lovley DR. Genome-scale dynamic modeling of the competition between Rhodoferax and Geobacter in anoxic subsurface environments. The Isme Journal. 5: 305-16. PMID 20668487 DOI: 10.1038/Ismej.2010.117  0.346
2011 Barlett M, Zhuang K, Mahadevan R, Lovley DR. Integrative analysis of the interactions between <i>Geobacter</i> spp. and sulfate-reducing bacteria during uranium bioremediation Biogeosciences Discussions. 8: 11337-11357. DOI: 10.5194/Bgd-8-11337-2011  0.322
2011 Pinel D, Gawand P, Mahadevan R, Martin VJJ. 'Omics' technologies and systems biology for engineering Saccharomyces cerevisiae strains for lignocellulosic bioethanol production Biofuels. 2: 659-675. DOI: 10.4155/bfs.11.120  0.811
2011 Anesiadis N, Cluett WR, Mahadevan R. Model-driven design based on sensitivity analysis for a synthetic biology application Computer Aided Chemical Engineering. 29: 1446-1450. DOI: 10.1016/B978-0-444-54298-4.50068-4  0.8
2011 Gawand P, Mahadevan R. Higher order gene deletion mutants give insights on latent pathway activation Aiche Annual Meeting, Conference Proceedings 0.772
2011 Anesiadis N, Cluett WR, Kobayashi H, Fong S, Mahadevan R. Dynamic metabolic engineering for lactate production Aiche Annual Meeting, Conference Proceedings 0.809
2011 Anesiadis N, Cluett WR, Kobayashi H, Fong S, Mahadevan R. Dynamic metabolic engineering for lactate production Aiche Annual Meeting, Conference Proceedings 0.809
2010 Ahsanul Islam M, Edwards EA, Mahadevan R. Characterizing the metabolism of Dehalococcoides with a constraint-based model. Plos Computational Biology. 6. PMID 20811585 DOI: 10.1371/Journal.Pcbi.1000887  0.471
2010 Salimi F, Zhuang K, Mahadevan R. Genome-scale metabolic modeling of a clostridial co-culture for consolidated bioprocessing. Biotechnology Journal. 5: 726-38. PMID 20665645 DOI: 10.1002/Biot.201000159  0.659
2010 Garg S, Yang L, Mahadevan R. Thermodynamic analysis of regulation in metabolic networks using constraint-based modeling. Bmc Research Notes. 3: 125. PMID 20444261 DOI: 10.1186/1756-0500-3-125  0.718
2010 Srinivasan K, Mahadevan R. Characterization of proton production and consumption associated with microbial metabolism. Bmc Biotechnology. 10: 2. PMID 20089195 DOI: 10.1186/1472-6750-10-2  0.392
2010 Zhao J, Fang Y, Scheibe TD, Lovley DR, Mahadevan R. Modeling and sensitivity analysis of electron capacitance for Geobacter in sedimentary environments. Journal of Contaminant Hydrology. 112: 30-44. PMID 19892431 DOI: 10.1016/J.Jconhyd.2009.10.002  0.308
2010 Jayasinghe N, Mahadevan R. Metabolic Modeling of Spatial Heterogeneity of Biofilms in Microbial Fuel Cells Ifac Proceedings Volumes. 43: 215-220. DOI: 10.3182/20100707-3-Be-2012.0050  0.385
2010 Salimi F, Mandal R, Wishart D, Mahadevan R. Understanding clostridium acetobutylicum ATCC 824 metabolism using genome-scale thermodynamics and metabolomics-based modeling Ifac Proceedings Volumes (Ifac-Papersonline). 11: 126-131. DOI: 10.3182/20100707-3-Be-2012.0022  0.724
2010 Yang L, Cluett WR, Mahadevan R. Rapid design of system-wide metabolic network modifications using iterative linear programming Ifac Proceedings Volumes (Ifac-Papersonline). 9: 391-396. DOI: 10.3182/20100705-3-Be-2011.00065  0.728
2009 Scheibe TD, Mahadevan R, Fang Y, Garg S, Long PE, Lovley DR. Coupling a genome-scale metabolic model with a reactive transport model to describe in situ uranium bioremediation. Microbial Biotechnology. 2: 274-86. PMID 21261921 DOI: 10.1111/J.1751-7915.2009.00087.X  0.374
2009 Risso C, Sun J, Zhuang K, Mahadevan R, DeBoy R, Ismail W, Shrivastava S, Huot H, Kothari S, Daugherty S, Bui O, Schilling CH, Lovley DR, Methé BA. Genome-scale comparison and constraint-based metabolic reconstruction of the facultative anaerobic Fe(III)-reducer Rhodoferax ferrireducens. Bmc Genomics. 10: 447. PMID 19772637 DOI: 10.1186/1471-2164-10-447  0.372
2009 Sun J, Sayyar B, Butler JE, Pharkya P, Fahland TR, Famili I, Schilling CH, Lovley DR, Mahadevan R. Genome-scale constraint-based modeling of Geobacter metallireducens. Bmc Systems Biology. 3: 15. PMID 19175927 DOI: 10.1186/1752-0509-3-15  0.405
2008 Izallalen M, Mahadevan R, Burgard A, Postier B, Didonato R, Sun J, Schilling CH, Lovley DR. Geobacter sulfurreducens strain engineered for increased rates of respiration. Metabolic Engineering. 10: 267-75. PMID 18644460 DOI: 10.1016/J.Ymben.2008.06.005  0.417
2008 Anesiadis N, Cluett WR, Mahadevan R. Dynamic metabolic engineering for increasing bioprocess productivity. Metabolic Engineering. 10: 255-66. PMID 18606241 DOI: 10.1016/J.Ymben.2008.06.004  0.821
2008 Mahadevan R, Yan B, Postier B, Nevin KP, Woodard TL, O'Neil R, Coppi MV, Methé BA, Krushkal J. Characterizing regulation of metabolism in Geobacter sulfurreducens through genome-wide expression data and sequence analysis. Omics : a Journal of Integrative Biology. 12: 33-59. PMID 18266557 DOI: 10.1089/Omi.2007.0043  0.446
2008 Segura D, Mahadevan R, Juárez K, Lovley DR. Computational and experimental analysis of redundancy in the central metabolism of Geobacter sulfurreducens. Plos Computational Biology. 4: e36. PMID 18266464 DOI: 10.1371/Journal.Pcbi.0040036  0.473
2008 Mahadevan R, Lovley DR. The degree of redundancy in metabolic genes is linked to mode of metabolism Biophysical Journal. 94: 1216-1220. PMID 17981891 DOI: 10.1529/Biophysj.107.118414  0.439
2008 Yang L, Mahadevan R, Cluett WR. A bilevel optimization algorithm to identify enzymatic capacity constraints in metabolic networks Computers and Chemical Engineering. 32: 2072-2085. DOI: 10.1016/J.Compchemeng.2007.10.015  0.728
2008 Dhurjati P, Mahadevan R. Systems biology: The synergistic interplay between biology and mathematics Canadian Journal of Chemical Engineering. 86: 127-141. DOI: 10.1002/Cjce.20025  0.309
2007 Oh YK, Palsson BO, Park SM, Schilling CH, Mahadevan R. Genome-scale reconstruction of metabolic network in Bacillus subtilis based on high-throughput phenotyping and gene essentiality data. The Journal of Biological Chemistry. 282: 28791-9. PMID 17573341 DOI: 10.1074/Jbc.M703759200  0.423
2007 Hjersted JL, Henson MA, Mahadevan R. Genome-scale analysis of Saccharomyces cerevisiae metabolism and ethanol production in fed-batch culture. Biotechnology and Bioengineering. 97: 1190-204. PMID 17243146 DOI: 10.1002/Bit.21332  0.439
2006 Mahadevan R, Bond DR, Butler JE, Esteve-Nuñez A, Coppi MV, Palsson BO, Schilling CH, Lovley DR. Characterization of metabolism in the Fe(III)-reducing organism Geobacter sulfurreducens by constraint-based modeling. Applied and Environmental Microbiology. 72: 1558-68. PMID 16461711 DOI: 10.1128/Aem.72.2.1558-1568.2006  0.425
2006 Gadkar KG, Mahadevan R, Doyle FJ. Optimal genetic manipulations in batch bioreactor control Automatica. 42: 1723-1733. DOI: 10.1016/J.Automatica.2006.05.004  0.521
2005 Famili I, Mahadevan R, Palsson BO. k-Cone analysis: determining all candidate values for kinetic parameters on a network scale. Biophysical Journal. 88: 1616-25. PMID 15626710 DOI: 10.1529/Biophysj.104.050385  0.333
2005 Gadkar KG, Doyle Iii FJ, Edwards JS, Mahadevan R. Estimating optimal profiles of genetic alterations using constraint-based models. Biotechnology and Bioengineering. 89: 243-51. PMID 15593263 DOI: 10.1002/Bit.20349  0.417
2005 Mahadevan R, Palsson BO. Properties of metabolic networks: structure versus function. Biophysical Journal. 88: L07-9. PMID 15574705 DOI: 10.1529/Biophysj.104.055723  0.34
2005 Mahadevan R, Burgard AP, Famili I, Van Dien S, Schilling CH. Applications of metabolic modeling to drive bioprocess development for the production of value-added chemicals Biotechnology and Bioprocess Engineering. 10: 408-417. DOI: 10.1007/Bf02989823  0.499
2004 Wiback SJ, Mahadevan R, Palsson BØ. Using metabolic flux data to further constrain the metabolic solution space and predict internal flux patterns: the Escherichia coli spectrum. Biotechnology and Bioengineering. 86: 317-31. PMID 15083512 DOI: 10.1002/Bit.20011  0.419
2004 Mahadevan R, Doyle FJ. A partial flatness approach to nonlinear moving horizon estimation Proceedings of the American Control Conference. 1: 211-215.  0.37
2003 Mahadevan R, Schilling CH. The effects of alternate optimal solutions in constraint-based genome-scale metabolic models Metabolic Engineering. 5: 264-276. PMID 14642354 DOI: 10.1016/J.Ymben.2003.09.002  0.402
2003 Wiback SJ, Mahadevan R, Palsson BØ. Reconstructing metabolic flux vectors from extreme pathways: defining the alpha-spectrum. Journal of Theoretical Biology. 224: 313-24. PMID 12941590 DOI: 10.1016/S0022-5193(03)00168-1  0.378
2003 Mahadevan R, Doyle III FJ. On-line optimization of recombinant product in a fed-batch bioreactor. Biotechnology Progress. 19: 639-46. PMID 12675609 DOI: 10.1021/Bp025546Z  0.343
2003 Mahadevan R, Doyle FJ. Efficient optimization approaches to nonlinear model predictive control International Journal of Robust and Nonlinear Control. 13: 309-329. DOI: 10.1002/Rnc.820  0.488
2002 Mahadevan R, Edwards JS, Doyle FJ. Dynamic flux balance analysis of diauxic growth in Escherichia coli. Biophysical Journal. 83: 1331-40. PMID 12202358 DOI: 10.1016/S0006-3495(02)73903-9  0.59
2002 Mahadevan R, Doyle FJ, Allcock AC. Control-relevant scheduling of polymer grade transitions Aiche Journal. 48: 1754-1764. DOI: 10.1002/Aic.690480816  0.436
2000 Mahadevan R, Agrawal SK, Doyle FJ. A Flatness Based Approach to Optimization in Fed-Batch Bioreactors Ifac Proceedings Volumes. 33: 111-116. DOI: 10.1016/S1474-6670(17)38527-0  0.462
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