Gerold Schmitt-Ulms - Publications

Affiliations: 
Laboratory Medicine and Pathobiology University of Toronto, Toronto, ON, Canada 
Area:
Genetics, Cell Biology, Neuroscience Biology, Bioinformatics Biology, Biochemistry

81 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Moustafa A, Hashemi S, Brar G, Grigull J, Ng SHS, Williams D, Schmitt-Ulms G, McDermott JC. The MEF2A transcription factor interactome in cardiomyocytes. Cell Death & Disease. 14: 240. PMID 37019881 DOI: 10.1038/s41419-023-05665-8  0.324
2023 Williams D, Yan BQ, Wang H, Negm L, Sackmann C, Verkuyl C, Rezai-Stevens V, Eid S, Vediya N, Sato C, Watts JC, Wille H, Schmitt-Ulms G. Somatostatin slows Aβ plaque deposition in aged APP mice by blocking Aβ aggregation. Scientific Reports. 13: 2337. PMID 36759538 DOI: 10.1038/s41598-023-29559-z  0.622
2022 Arshad H, Patel Z, Amano G, Li LY, Al-Azzawi ZAM, Supattapone S, Schmitt-Ulms G, Watts JC. A Single Protective Polymorphism in the Prion Protein Blocks Cross-Species Prion Replication in Cultured Cells. Journal of Neurochemistry. PMID 36511154 DOI: 10.1111/jnc.15739  0.748
2021 Williams D, Mehrabian M, Arshad H, Eid S, Sackmann C, Zhao W, Wang X, Ghodrati F, Verkuyl CE, Watts JC, Schmitt-Ulms G. The cellular prion protein interacts with and promotes the activity of Na,K-ATPases. Plos One. 16: e0258682. PMID 34847154 DOI: 10.1371/journal.pone.0258682  0.687
2021 Arshad H, Patel Z, Mehrabian M, Bourkas MEC, Al-Azzawi ZAM, Schmitt-Ulms G, Watts JC. The aminoglycoside G418 hinders de novo prion infection in cultured cells. The Journal of Biological Chemistry. 101073. PMID 34390689 DOI: 10.1016/j.jbc.2021.101073  0.625
2021 Ruiz-Riquelme A, Mao A, Barghash MM, Lau HHC, Stuart E, Kovacs GG, Nilsson KPR, Fraser PE, Schmitt-Ulms G, Watts JC. Aβ43 aggregates exhibit enhanced prion-like seeding activity in mice. Acta Neuropathologica Communications. 9: 83. PMID 33971978 DOI: 10.1186/s40478-021-01187-6  0.614
2021 Schmitt-Ulms G, Mehrabian M, Williams D, Ehsani S. The IDIP framework for assessing protein function and its application to the prion protein. Biological Reviews of the Cambridge Philosophical Society. PMID 33960099 DOI: 10.1111/brv.12731  0.663
2019 Wille H, Dorosh L, Amidian S, Schmitt-Ulms G, Stepanova M. Combining molecular dynamics simulations and experimental analyses in protein misfolding. Advances in Protein Chemistry and Structural Biology. 118: 33-110. PMID 31928730 DOI: 10.1016/Bs.Apcsb.2019.10.001  0.447
2019 Wang X, Williams D, Müller I, Lemieux M, Dukart R, Maia IBL, Wang H, Woerman AL, Schmitt-Ulms G. Tau interactome analyses in CRISPR-Cas9 engineered neuronal cells reveal ATPase-dependent binding of wild-type but not P301L Tau to non-muscle myosins. Scientific Reports. 9: 16238. PMID 31700063 DOI: 10.1038/S41598-019-52543-5  0.71
2019 Solarski M, Williams D, Mehrabian M, Wang H, Wille H, Schmitt-Ulms G. The human brain somatostatin interactome: SST binds selectively to P-type family ATPases. Plos One. 14: e0217392. PMID 31136617 DOI: 10.1371/Journal.Pone.0217392  0.404
2019 Bourkas MEC, Arshad H, Al-Azzawi ZAM, Halgas O, Shikiya RA, Mehrabian M, Schmitt-Ulms G, Bartz JC, Watts JC. Engineering a murine cell line for the stable propagation of hamster prions. The Journal of Biological Chemistry. PMID 30705093 DOI: 10.1074/Jbc.Ra118.007135  0.676
2018 Ghodrati F, Mehrabian M, Williams D, Halgas O, Bourkas MEC, Watts JC, Pai EF, Schmitt-Ulms G. The prion protein is embedded in a molecular environment that modulates transforming growth factor β and integrin signaling. Scientific Reports. 8: 8654. PMID 29872131 DOI: 10.1038/S41598-018-26685-X  0.731
2018 Qamar S, Wang G, Randle SJ, Ruggeri FS, Varela JA, Lin JQ, Phillips EC, Miyashita A, Williams D, Ströhl F, Meadows W, Ferry R, Dardov VJ, Tartaglia GG, Farrer LA, ... ... Schmitt-Ulms G, et al. FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions. Cell. 173: 720-734.e15. PMID 29677515 DOI: 10.1016/J.Cell.2018.03.056  0.357
2018 Ruiz-Riquelme A, Lau HHC, Stuart E, Goczi AN, Wang Z, Schmitt-Ulms G, Watts JC. Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression. Acta Neuropathologica Communications. 6: 26. PMID 29615128 DOI: 10.1186/S40478-018-0529-X  0.647
2017 Solarski M, Wang H, Wille H, Schmitt-Ulms G. Somatostatin in Alzheimer'S disease: A new Role for an Old Player. Prion. 0. PMID 29192843 DOI: 10.1080/19336896.2017.1405207  0.376
2017 Wang H, Williams D, Griffin J, Saito T, Saido TC, Fraser PE, Rogaeva E, Schmitt-Ulms G. Time-course global proteome analyses reveal an inverse correlation between Aβ burden and immunoglobulin M levels in the APPNL-F mouse model of Alzheimer disease. Plos One. 12: e0182844. PMID 28832675 DOI: 10.1371/Journal.Pone.0182844  0.373
2017 Wang H, Muiznieks LD, Ghosh P, Williams D, Solarski M, Fang A, Ruiz-Riquelme A, Pomès R, Watts JC, Chakrabartty A, Wille H, Sharpe S, Schmitt-Ulms G. Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers. Elife. 6. PMID 28650319 DOI: 10.7554/Elife.28401  0.656
2017 Brethour D, Mehrabian M, Williams D, Wang X, Ghodrati F, Ehsani S, Rubie EA, Woodgett JR, Sevalle J, Xi Z, Rogaeva E, Schmitt-Ulms G. A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition. Scientific Reports. 7: 40313. PMID 28098160 DOI: 10.1038/Srep40313  0.683
2017 Wang H, Muiznieks LD, Ghosh P, Williams D, Solarski M, Fang A, Ruiz-Riquelme A, Pomès R, Watts JC, Chakrabartty A, Wille H, Sharpe S, Schmitt-Ulms G. Author response: Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers Elife. DOI: 10.7554/Elife.28401.022  0.623
2017 Hu J, Wille H, Schmitt-Ulms G. The Evolutionary unZIPping of a Dimerization Motif—A Comparison of ZIP and PrP Architectures Pathogens. 7: 4. DOI: 10.3390/Pathogens7010004  0.439
2016 Mehrabian M, Hildebrandt H, Schmitt-Ulms G. NCAM1 Polysialylation: The Prion Protein's Elusive Reason for Being? Asn Neuro. 8. PMID 27879349 DOI: 10.1177/1759091416679074  0.444
2016 Rogaeva E, Schmitt-Ulms G. Does BDNF Val66Met contribute to preclinical Alzheimer's disease? Brain : a Journal of Neurology. 139: 2586-2589. PMID 27671028 DOI: 10.1093/Brain/Aww201  0.302
2016 Mehrabian M, Brethour D, Williams D, Wang H, Arnould H, Schneider B, Schmitt-Ulms G. Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue. Plos One. 11: e0156779. PMID 27327609 DOI: 10.1371/Journal.Pone.0156779  0.453
2016 Taylor KM, Muraina I, Brethour D, Schmitt-Ulms G, Nimmanon T, Ziliotto S, Kille P, Hogstrand C. Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration. The Biochemical Journal. PMID 27274087 DOI: 10.1042/Bcj20160388  0.318
2015 Murakami T, Qamar S, Lin JQ, Schierle GS, Rees E, Miyashita A, Costa AR, Dodd RB, Chan FT, Michel CH, Kronenberg-Versteeg D, Li Y, Yang SP, Wakutani Y, Meadows W, ... ... Schmitt-Ulms G, et al. ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function. Neuron. PMID 26526393 DOI: 10.1016/J.Neuron.2015.10.030  0.334
2015 Mehrabian M, Brethour D, Wang H, Xi Z, Rogaeva E, Schmitt-Ulms G. The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis. Plos One. 10: e0133741. PMID 26288071 DOI: 10.1371/Journal.Pone.0133741  0.432
2015 Gunawardana CG, Mehrabian M, Wang X, Mueller I, Lubambo IB, Jonkman JE, Wang H, Schmitt-Ulms G. The Human Tau Interactome: Binding to the Ribonucleoproteome, and Impaired Binding of the Proline-to-Leucine Mutant at Position 301 (P301L) to Chaperones and the Proteasome. Molecular & Cellular Proteomics : McP. 14: 3000-14. PMID 26269332 DOI: 10.1074/Mcp.M115.050724  0.443
2015 Bohm C, Chen F, Sevalle J, Qamar S, Dodd R, Li Y, Schmitt-Ulms G, Fraser PE, St George-Hyslop PH. Current and future implications of basic and translational research on amyloid-β peptide production and removal pathways. Molecular and Cellular Neurosciences. 66: 3-11. PMID 25748120 DOI: 10.1016/J.Mcn.2015.02.016  0.397
2015 Lau A, McDonald A, Daude N, Mays CE, Walter ED, Aglietti R, Mercer RC, Wohlgemuth S, van der Merwe J, Yang J, Gapeshina H, Kim C, Grams J, Shi B, Wille H, ... ... Schmitt-Ulms G, et al. Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation. Embo Molecular Medicine. 7: 339-56. PMID 25661904 DOI: 10.15252/Emmm.201404588  0.379
2014 Li Y, Bohm C, Dodd R, Chen F, Qamar S, Schmitt-Ulms G, Fraser PE, St George-Hyslop PH. Structural biology of presenilin 1 complexes. Molecular Neurodegeneration. 9: 59. PMID 25523933 DOI: 10.1186/1750-1326-9-59  0.377
2014 Mehrabian M, Brethour D, MacIsaac S, Kim JK, Gunawardana CG, Wang H, Schmitt-Ulms G. CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome. Plos One. 9: e114594. PMID 25490046 DOI: 10.1371/Journal.Pone.0114594  0.502
2014 Mehrabian M, Ehsani S, Schmitt-Ulms G. An emerging role of the cellular prion protein as a modulator of a morphogenetic program underlying epithelial-to-mesenchymal transition. Frontiers in Cell and Developmental Biology. 2: 53. PMID 25453033 DOI: 10.3389/Fcell.2014.00053  0.7
2014 Mays CE, Coomaraswamy J, Watts JC, Yang J, Ko KW, Strome B, Mercer RC, Wohlgemuth SL, Schmitt-Ulms G, Westaway D. Endoproteolytic processing of the mammalian prion glycoprotein family. The Febs Journal. 281: 862-76. PMID 24286250 DOI: 10.1111/Febs.12654  0.646
2014 Li Y, Lu SH, Tsai CJ, Bohm C, Qamar S, Dodd RB, Meadows W, Jeon A, McLeod A, Chen F, Arimon M, Berezovska O, Hyman BT, Tomita T, Iwatsubo T, ... ... Schmitt-Ulms G, et al. Structural interactions between inhibitor and substrate docking sites give insight into mechanisms of human PS1 complexes. Structure (London, England : 1993). 22: 125-35. PMID 24210759 DOI: 10.1016/J.Str.2013.09.018  0.767
2013 Mercer RC, Ma L, Watts JC, Strome R, Wohlgemuth S, Yang J, Cashman NR, Coulthart MB, Schmitt-Ulms G, Jhamandas JH, Westaway D. The prion protein modulates A-type K+ currents mediated by Kv4.2 complexes through dipeptidyl aminopeptidase-like protein 6. The Journal of Biological Chemistry. 288: 37241-55. PMID 24225951 DOI: 10.1074/Jbc.M113.488650  0.684
2013 Pocanschi CL, Ehsani S, Mehrabian M, Wille H, Reginold W, Trimble WS, Wang H, Yee A, Arrowsmith CH, Bozóky Z, Kay LE, Forman-Kay JD, Rini JM, Schmitt-Ulms G. The ZIP5 ectodomain co-localizes with PrP and may acquire a PrP-like fold that assembles into a dimer. Plos One. 8: e72446. PMID 24039764 DOI: 10.1371/Journal.Pone.0072446  0.71
2013 Wang H, Ren CH, Gunawardana CG, Schmitt-Ulms G. Overcoming barriers and thresholds - signaling of oligomeric Aβ through the prion protein to Fyn. Molecular Neurodegeneration. 8: 24. PMID 23856335 DOI: 10.1186/1750-1326-8-24  0.392
2013 Jeon AH, Böhm C, Chen F, Huo H, Ruan X, Ren CH, Ho K, Qamar S, Mathews PM, Fraser PE, Mount HT, St George-Hyslop P, Schmitt-Ulms G. Interactome analyses of mature γ-secretase complexes reveal distinct molecular environments of presenilin (PS) paralogs and preferential binding of signal peptide peptidase to PS2. The Journal of Biological Chemistry. 288: 15352-66. PMID 23589300 DOI: 10.1074/Jbc.M112.441840  0.787
2013 Boehm C, Jeon AHW, Chen F, Fraser P, Mount H, George-Hyslop PS, Schmitt-Ulms G. Interactome analyses of mature gamma-secretase complexes reveals distinct molecular environments of presenilin paralogs and preferential binding of signal peptide peptidase to PS2 Alzheimers & Dementia. 9: 364. DOI: 10.1016/J.Jalz.2013.05.700  0.371
2012 Ehsani S, Salehzadeh A, Huo H, Reginold W, Pocanschi CL, Ren H, Wang H, So K, Sato C, Mehrabian M, Strome R, Trimble WS, Hazrati LN, Rogaeva E, Westaway D, ... ... Schmitt-Ulms G, et al. LIV-1 ZIP ectodomain shedding in prion-infected mice resembles cellular response to transition metal starvation. Journal of Molecular Biology. 422: 556-74. PMID 22687393 DOI: 10.1016/J.Jmb.2012.06.003  0.707
2012 Lu SH, Jeon AH, Schmitt-Ulms G, Qamar S, Dodd R, McDonald B, Li Y, Meadows W, Cox K, Bohm C, Chen F, Fraser P, George-Hyslop PS. Vigilin interacts with signal peptide peptidase. Proteome Science. 10: 33. PMID 22607704 DOI: 10.1186/1477-5956-10-33  0.807
2012 Ehsani S, Mehrabian M, Pocanschi CL, Schmitt-Ulms G. The ZIP-prion connection. Prion. 6: 317-21. PMID 22575750 DOI: 10.4161/Pri.20196  0.642
2012 Harbi D, Parthiban M, Gendoo DM, Ehsani S, Kumar M, Schmitt-Ulms G, Sowdhamini R, Harrison PM. PrionHome: a database of prions and other sequences relevant to prion phenomena. Plos One. 7: e31785. PMID 22363733 DOI: 10.1371/journal.pone.0031785  0.657
2012 Jeon AH, Schmitt-Ulms G. Time-controlled transcardiac perfusion crosslinking for in vivo interactome studies. Methods in Molecular Biology (Clifton, N.J.). 803: 231-46. PMID 22065229 DOI: 10.1007/978-1-61779-364-6_16  0.793
2011 Westaway D, Genovesi S, Daude N, Brown R, Lau A, Lee I, Mays CE, Coomaraswamy J, Canine B, Pitstick R, Herbst A, Yang J, Ko KW, Schmitt-Ulms G, Dearmond SJ, et al. Down-regulation of Shadoo in prion infections traces a pre-clinical event inversely related to PrP(Sc) accumulation. Plos Pathogens. 7: e1002391. PMID 22114562 DOI: 10.1371/Journal.Ppat.1002391  0.443
2011 Ehsani S, Tao R, Pocanschi CL, Ren H, Harrison PM, Schmitt-Ulms G. Evidence for retrogene origins of the prion gene family. Plos One. 6: e26800. PMID 22046361 DOI: 10.1371/Journal.Pone.0026800  0.641
2011 Knobbe CB, Revett TJ, Bai Y, Chow V, Jeon AH, Böhm C, Ehsani S, Kislinger T, Mount HT, Mak TW, St George-Hyslop P, Schmitt-Ulms G. Choice of biological source material supersedes oxidative stress in its influence on DJ-1 in vivo interactions with Hsp90. Journal of Proteome Research. 10: 4388-404. PMID 21819105 DOI: 10.1021/Pr200225C  0.77
2011 Pasic MD, Diamandis EP, McLaurin J, Holtzman DM, Schmitt-Ulms G, Quirion R. Alzheimer disease: advances in pathogenesis, diagnosis, and therapy. Clinical Chemistry. 57: 664-9. PMID 21310870 DOI: 10.1373/Clinchem.2011.161828  0.301
2011 Ehsani S, Huo H, Salehzadeh A, Pocanschi CL, Watts JC, Wille H, Westaway D, Rogaeva E, St George-Hyslop PH, Schmitt-Ulms G. Family reunion--the ZIP/prion gene family. Progress in Neurobiology. 93: 405-20. PMID 21163327 DOI: 10.1016/J.Pneurobio.2010.12.001  0.786
2010 St George-Hyslop P, Schmitt-Ulms G. Alzheimer's disease: Selectively tuning gamma-secretase. Nature. 467: 36-7. PMID 20811445 DOI: 10.1038/467036A  0.383
2010 Poulsen C, Akhter Y, Jeon AH, Schmitt-Ulms G, Meyer HE, Stefanski A, Stühler K, Wilmanns M, Song YH. Proteome-wide identification of mycobacterial pupylation targets. Molecular Systems Biology. 6: 386. PMID 20631680 DOI: 10.1038/Msb.2010.39  0.775
2010 Daude N, Ng V, Watts JC, Genovesi S, Glaves JP, Wohlgemuth S, Schmitt-Ulms G, Young H, McLaurin J, Fraser PE, Westaway D. Wild-type Shadoo proteins convert to amyloid-like forms under native conditions. Journal of Neurochemistry. 113: 92-104. PMID 20067571 DOI: 10.1111/J.1471-4159.2010.06575.X  0.701
2010 Wille H, Ehsani S, Watts JC, Westaway D, Schmitt-Ulms G. Descent of the Prion Protein Gene Family from the Extracellular Domain of an Ancestral Zip Metal Ion Transporter Biophysical Journal. 98: 708a. DOI: 10.1016/J.Bpj.2009.12.3883  0.795
2009 Shi T, Weerasekera R, Yan C, Reginold W, Ball H, Kislinger T, Schmitt-Ulms G. Method for the affinity purification of covalently linked peptides following cyanogen bromide cleavage of proteins. Analytical Chemistry. 81: 9885-95. PMID 19924875 DOI: 10.1021/Ac901373Q  0.395
2009 Watts JC, Huo H, Bai Y, Ehsani S, Jeon AH, Won AH, Shi T, Daude N, Lau A, Young R, Xu L, Carlson GA, Williams D, Westaway D, Schmitt-Ulms G. Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperones. Plos Pathogens. 5: e1000608. PMID 19798432 DOI: 10.1371/Journal.Ppat.1000608  0.789
2009 Schmitt-Ulms G, Ehsani S, Watts JC, Westaway D, Wille H. Evolutionary descent of prion genes from the ZIP family of metal ion transporters. Plos One. 4: e7208. PMID 19784368 DOI: 10.1371/Journal.Pone.0007208  0.788
2009 Pardossi-Piquard R, Böhm C, Chen F, Kanemoto S, Checler F, Schmitt-Ulms G, St George-Hyslop P, Fraser PE. TMP21 transmembrane domain regulates gamma-secretase cleavage. The Journal of Biological Chemistry. 284: 28634-41. PMID 19710022 DOI: 10.1074/Jbc.M109.059345  0.349
2009 Elschenbroich S, Ignatchenko V, Sharma P, Schmitt-Ulms G, Gramolini AO, Kislinger T. Peptide separations by on-line MudPIT compared to isoelectric focusing in an off-gel format: application to a membrane-enriched fraction from C2C12 mouse skeletal muscle cells. Journal of Proteome Research. 8: 4860-9. PMID 19670906 DOI: 10.1021/Pr900318K  0.326
2009 Schmitt-Ulms G, Matenia D, Drewes G, Mandelkow EM. Interactions of MAP/microtubule affinity regulating kinases with the adaptor complex AP-2 of clathrin-coated vesicles. Cell Motility and the Cytoskeleton. 66: 661-72. PMID 19536824 DOI: 10.1002/Cm.20394  0.528
2009 Pardossi-Piquard R, Yang SP, Kanemoto S, Gu Y, Chen F, Böhm C, Sevalle J, Li T, Wong PC, Checler F, Schmitt-Ulms G, St George-Hyslop P, Fraser PE. APH1 polar transmembrane residues regulate the assembly and activity of presenilin complexes. The Journal of Biological Chemistry. 284: 16298-307. PMID 19369254 DOI: 10.1074/Jbc.M109.000067  0.348
2009 Schmitt-Ulms G, Ehsani S, Watts JC, Westaway D, Wille H. Evolutionary descent of prion genes from a ZIP metal ion transport ancestor Nature Precedings. 4: 1-1. DOI: 10.1038/Npre.2009.2867.1  0.726
2008 Gortzak-Uzan L, Ignatchenko A, Evangelou AI, Agochiya M, Brown KA, St Onge P, Kireeva I, Schmitt-Ulms G, Brown TJ, Murphy J, Rosen B, Shaw P, Jurisica I, Kislinger T. A proteome resource of ovarian cancer ascites: integrated proteomic and bioinformatic analyses to identify putative biomarkers. Journal of Proteome Research. 7: 339-51. PMID 18076136 DOI: 10.1021/Pr0703223  0.346
2008 Bai Y, Markham K, Chen F, Weerasekera R, Watts J, Horne P, Wakutani Y, Bagshaw R, Mathews PM, Fraser PE, Westaway D, St George-Hyslop P, Schmitt-Ulms G. The in vivo brain interactome of the amyloid precursor protein. Molecular & Cellular Proteomics : McP. 7: 15-34. PMID 17934213 DOI: 10.1074/Mcp.M700077-Mcp200  0.724
2008 Weerasekera R, Shi T, Schmitt-Ulms G. Chapter 11 Covalent Trapping of Protein Interactions in Complex Systems Comprehensive Analytical Chemistry. 52. DOI: 10.1016/S0166-526X(08)00211-0  0.402
2007 Weerasekera R, She YM, Markham KA, Bai Y, Opalka N, Orlicky S, Sicheri F, Kislinger T, Schmitt-Ulms G. Interactome and interface protocol (2IP): a novel strategy for high sensitivity topology mapping of protein complexes. Proteomics. 7: 3835-52. PMID 17960736 DOI: 10.1002/Pmic.200700688  0.399
2007 Watts JC, Drisaldi B, Ng V, Yang J, Strome B, Horne P, Sy MS, Yoong L, Young R, Mastrangelo P, Bergeron C, Fraser PE, Carlson GA, Mount HT, Schmitt-Ulms G, et al. The CNS glycoprotein Shadoo has PrP(C)-like protective properties and displays reduced levels in prion infections. The Embo Journal. 26: 4038-50. PMID 17703189 DOI: 10.1038/Sj.Emboj.7601830  0.698
2007 Markham K, Bai Y, Schmitt-Ulms G. Co-immunoprecipitations revisited: an update on experimental concepts and their implementation for sensitive interactome investigations of endogenous proteins. Analytical and Bioanalytical Chemistry. 389: 461-73. PMID 17583802 DOI: 10.1007/S00216-007-1385-X  0.383
2007 Rogaeva E, Meng Y, Lee JH, Gu Y, Kawarai T, Zou F, Katayama T, Baldwin CT, Cheng R, Hasegawa H, Chen F, Shibata N, Lunetta KL, Pardossi-Piquard R, Bohm C, ... ... Schmitt-Ulms G, et al. The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nature Genetics. 39: 168-77. PMID 17220890 DOI: 10.1038/Ng1943  0.372
2006 Weerasekera R, Schmitt-Ulms G. Crosslinking strategies for the study of membrane protein complexes and protein interaction interfaces. Biotechnology & Genetic Engineering Reviews. 23: 41-62. PMID 22530501 DOI: 10.1080/02648725.2006.10648077  0.419
2006 Chen F, Hasegawa H, Schmitt-Ulms G, Kawarai T, Bohm C, Katayama T, Gu Y, Sanjo N, Glista M, Rogaeva E, Wakutani Y, Pardossi-Piquard R, Ruan X, Tandon A, Checler F, et al. TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity. Nature. 440: 1208-12. PMID 16641999 DOI: 10.1038/Nature04667  0.457
2006 Ng VW, Watts JC, Schmitt-Ulms G, Westaway D. P4-150: Preliminary characterization and structural analysis of the prion protein Homolog, Shadoo Alzheimer's & Dementia. 2: S560-S560. DOI: 10.1016/J.Jalz.2006.05.1889  0.672
2006 Watts JC, Drisaldi B, Strome B, Yang J, Fraser PE, Mount HT, Schmitt-Ulms G, Westaway D. P4-149: Shadoo is a novel mammalian protein exhibiting partial redundancy with PRPC Alzheimer's & Dementia. 2: S559-S559. DOI: 10.1016/J.Jalz.2006.05.1888  0.674
2006 Chen F, Schmitt-Ulms G, Hasegawa H, Fraser P, George-Hyslop PS. P3-419: Identification of presenilin-associated proteins and potential regulators of the gamma-secretase complex Alzheimer's & Dementia. 2: S499-S499. DOI: 10.1016/J.Jalz.2006.05.1690  0.374
2006 Hasegawa H, Chen F, Schmitt-Ulms G, Kawarai T, Bohm C, Katayama T, Gu Y, Fraser PE, St. George-Hyslop P. P3-392: p24 family proteins have different function in APP processing Alzheimer's & Dementia. 2: S491-S491. DOI: 10.1016/J.Jalz.2006.05.1662  0.333
2004 Hasegawa H, Sanjo N, Chen F, Gu YJ, Shier C, Petit A, Kawarai T, Katayama T, Schmidt SD, Mathews PM, Schmitt-Ulms G, Fraser PE, St George-Hyslop P. Both the sequence and length of the C terminus of PEN-2 are critical for intermolecular interactions and function of presenilin complexes. The Journal of Biological Chemistry. 279: 46455-63. PMID 15322109 DOI: 10.1074/Jbc.M406289200  0.428
2004 Schmitt-Ulms G, Hansen K, Liu J, Cowdrey C, Yang J, DeArmond SJ, Cohen FE, Prusiner SB, Baldwin MA. Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues. Nature Biotechnology. 22: 724-31. PMID 15146195 DOI: 10.1038/Nbt969  0.675
2004 Gu Y, Sanjo N, Chen F, Hasegawa H, Petit A, Ruan X, Li W, Shier C, Kawarai T, Schmitt-Ulms G, Westaway D, St George-Hyslop P, Fraser PE. The presenilin proteins are components of multiple membrane-bound complexes that have different biological activities. The Journal of Biological Chemistry. 279: 31329-36. PMID 15123598 DOI: 10.1074/Jbc.M401548200  0.4
2003 Hansen KC, Schmitt-Ulms G, Chalkley RJ, Hirsch J, Baldwin MA, Burlingame AL. Mass spectrometric analysis of protein mixtures at low levels using cleavable 13C-isotope-coded affinity tag and multidimensional chromatography. Molecular & Cellular Proteomics : McP. 2: 299-314. PMID 12766231 DOI: 10.1074/Mcp.M300021-Mcp200  0.383
2001 Schmitt-Ulms G, Legname G, Baldwin MA, Ball HL, Bradon N, Bosque PJ, Crossin KL, Edelman GM, DeArmond SJ, Cohen FE, Prusiner SB. Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein. Journal of Molecular Biology. 314: 1209-25. PMID 11743735 DOI: 10.1006/jmbi.2000.5183  0.609
2001 Peretz D, Williamson RA, Kaneko K, Vergara J, Leclerc E, Schmitt-Ulms G, Mehlhorn IR, Legname G, Wormald MR, Rudd PM, Dwek RA, Burton DR, Prusiner SB. Antibodies inhibit prion propagation and clear cell cultures of prion infectivity. Nature. 412: 739-43. PMID 11507642 DOI: 10.1038/35089090  0.583
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