Reisa Sperling, MD - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 

285 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Buckley RF, Mormino EC, Chhatwal J, Schultz AP, Rabin JS, Rentz DM, Acar D, Properzi MJ, Dumurgier J, Jacobs H, Gomez-Isla T, Johnson KA, Sperling RA, Hanseeuw BJ. Associations between baseline amyloid, sex, and APOE on subsequent tau accumulation in cerebrospinal fluid. Neurobiology of Aging. 78: 178-185. PMID 30947113 DOI: 10.1016/j.neurobiolaging.2019.02.019  0.48
2019 Yang HS, Chhatwal JP, Xu J, White CC, Hanseeuw B, Rabin JS, Papp KV, Buckley RF, Schultz AP, Properzi MJ, Gatchel JR, Amariglio RE, Donovan NJ, Mormino EC, Hedden T, ... ... Sperling RA, et al. An UNC5C Allele Predicts Cognitive Decline and Hippocampal Atrophy in Clinically Normal Older Adults. Journal of Alzheimer's Disease : Jad. PMID 30883345 DOI: 10.3233/JAD-180788  0.48
2019 Hanseeuw BJ, Lopera F, Sperling RA, Norton DJ, Guzman-Velez E, Baena A, Pardilla-Delgado E, Schultz AP, Gatchel J, Jin D, Chen K, Reiman EM, Johnson KA, Quiroz YT. Striatal amyloid is associated with tauopathy and memory decline in familial Alzheimer's disease. Alzheimer's Research & Therapy. 11: 17. PMID 30717814 DOI: 10.1186/s13195-019-0468-1  0.48
2019 Buckley RF, Mormino EC, Rabin JS, Hohman TJ, Landau S, Hanseeuw BJ, Jacobs HIL, Papp KV, Amariglio RE, Properzi MJ, Schultz AP, Kirn D, Scott MR, Hedden T, Farrell M, ... ... Sperling RA, et al. Sex Differences in the Association of Global Amyloid and Regional Tau Deposition Measured By Positron Emission Tomography in Clinically Normal Older Adults. Jama Neurology. PMID 30715078 DOI: 10.1001/jamaneurol.2018.4693  0.48
2019 Halawa OA, Gatchel JR, Amariglio RE, Rentz DM, Sperling RA, Johnson KA, Marshall GA. Inferior and medial temporal tau and cortical amyloid are associated with daily functional impairment in Alzheimer's disease. Alzheimer's Research & Therapy. 11: 14. PMID 30704519 DOI: 10.1186/s13195-019-0471-6  0.44
2019 Tan CH, Bonham LW, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Yokoyama JS, Rabinovici GD, Miller BL, Yaffe K, Schellenberg GD, Kauppi K, Holland D, McEvoy LK, ... ... Sperling RA, et al. Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration. Brain : a Journal of Neurology. PMID 30689776 DOI: 10.1093/brain/awy327  0.32
2019 Marshall GA, Gatchel JR, Donovan NJ, Muniz MC, Schultz AP, Becker JA, Chhatwal JP, Hanseeuw BJ, Papp KV, Amariglio RE, Rentz DM, Sperling RA, Johnson KA. Regional Tau Correlates of Instrumental Activities of Daily Living and Apathy in Mild Cognitive Impairment and Alzheimer's Disease Dementia. Journal of Alzheimer's Disease : Jad. 67: 757-768. PMID 30689584 DOI: 10.3233/JAD-170578  0.48
2019 Marshall GA, Aghjayan SL, Dekhtyar M, Locascio JJ, Jethwani K, Amariglio RE, Czaja SJ, Loewenstein DA, Johnson KA, Sperling RA, Rentz DM. Measuring instrumental activities of daily living in non-demented elderly: a comparison of the new performance-based Harvard Automated Phone Task with other functional assessments. Alzheimer's Research & Therapy. 11: 4. PMID 30630529 DOI: 10.1186/s13195-018-0464-x  0.44
2018 Rabin JS, Yang HS, Schultz AP, Hanseeuw BJ, Hedden T, Viswanathan A, Gatchel JR, Marshall GA, Kilpatrick E, Klein H, Rao V, Buckley RF, Yau WW, Kirn DR, Rentz DM, ... ... Sperling RA, et al. Vascular risk and β-amyloid are synergistically associated with cortical tau. Annals of Neurology. PMID 30565287 DOI: 10.1002/ana.25399  0.48
2018 d'Oleire Uquillas F, Jacobs HIL, Biddle KD, Properzi M, Hanseeuw B, Schultz AP, Rentz DM, Johnson KA, Sperling RA, Donovan NJ. Regional tau pathology and loneliness in cognitively normal older adults. Translational Psychiatry. 8: 282. PMID 30563962 DOI: 10.1038/s41398-018-0345-x  0.48
2018 Hanseeuw BJ, Jonas V, Jackson J, Betensky RA, Rentz DM, Johnson KA, Sperling RA, Donovan NJ. Correction: Association of anxiety with subcortical amyloidosis in cognitively normal older adults. Molecular Psychiatry. PMID 30538309 DOI: 10.1038/s41380-018-0323-y  0.44
2018 Huijbers W, Schultz AP, Papp KV, LaPoint MR, Hanseeuw B, Chhatwal JP, Hedden T, Johnson KA, Sperling RA. Tau accumulation in clinically normal older adults is associated with hippocampal hyperactivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30482786 DOI: 10.1523/JNEUROSCI.1397-18.2018  0.64
2018 Properzi MJ, Buckley RF, Chhatwal JP, Donohue MC, Lois C, Mormino EC, Johnson KA, Sperling RA, Schultz AP. Nonlinear Distributional Mapping (NoDiM) for harmonization across amyloid-PET radiotracers. Neuroimage. PMID 30458305 DOI: 10.1016/j.neuroimage.2018.11.019  0.48
2018 Chen Z, Mengel D, Keshavan A, Rissman RA, Billinton A, Perkinton M, Percival-Alwyn J, Schultz A, Properzi M, Johnson K, Selkoe DJ, Sperling RA, Patel P, Zetterberg H, Galasko D, et al. Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30419228 DOI: 10.1016/j.jalz.2018.09.010  0.4
2018 Broce IJ, Tan CH, Fan CC, Jansen I, Savage JE, Witoelar A, Wen N, Hess CP, Dillon WP, Glastonbury CM, Glymour M, Yokoyama JS, Elahi FM, Rabinovici GD, Miller BL, ... ... Sperling RA, et al. Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease. Acta Neuropathologica. PMID 30413934 DOI: 10.1007/s00401-018-1928-6  0.32
2018 Sepulcre J, Grothe MJ, d'Oleire Uquillas F, Ortiz-Terán L, Diez I, Yang HS, Jacobs HIL, Hanseeuw BJ, Li Q, El-Fakhri G, Sperling RA, Johnson KA. Neurogenetic contributions to amyloid beta and tau spreading in the human cortex. Nature Medicine. PMID 30374196 DOI: 10.1038/s41591-018-0206-4  0.44
2018 Amariglio RE, Buckley RF, Mormino EC, Marshall GA, Johnson KA, Rentz DM, Sperling RA. Amyloid-associated increases in longitudinal report of subjective cognitive complaints. Alzheimer's & Dementia (New York, N. Y.). 4: 444-449. PMID 30258973 DOI: 10.1016/j.trci.2018.08.005  0.44
2018 Rieckmann A, Johnson KA, Sperling RA, Buckner RL, Hedden T. Dedifferentiation of caudate functional connectivity and striatal dopamine transporter density predict memory change in normal aging. Proceedings of the National Academy of Sciences of the United States of America. PMID 30224467 DOI: 10.1073/pnas.1804641115  0.48
2018 Chhatwal JP, Schultz AP, Hedden T, Boot BP, Wigman S, Rentz D, Johnson KA, Sperling RA. Anticholinergic Amnesia is Mediated by Alterations in Human Network Connectivity Architecture. Cerebral Cortex (New York, N.Y. : 1991). PMID 30192928 DOI: 10.1093/cercor/bhy214  0.48
2018 Hanseeuw BJ, Jonas V, Jackson J, Betensky RA, Rentz DM, Johnson KA, Sperling RA, Donovan NJ. Association of anxiety with subcortical amyloidosis in cognitively normal older adults. Molecular Psychiatry. PMID 30116029 DOI: 10.1038/s41380-018-0214-2  0.44
2018 Guzmán-Vélez E, Jaimes S, Aguirre-Acevedo DC, Norton DJ, Papp KV, Amariglio R, Rentz D, Baena A, Henao E, Tirado V, Muñoz C, Giraldo M, Sperling RA, Lopera F, Quiroz YT. A Three-Factor Structure of Cognitive Functioning Among Carriers and Non-Carriers of Autosomal-Dominant Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 30040714 DOI: 10.3233/JAD-180078  0.44
2018 Munro CE, Donovan NJ, Amariglio RE, Papp KV, Marshall GA, Rentz DM, Pascual-Leone A, Sperling RA, Locascio JJ, Vannini P. The Impact of Awareness of and Concern About Memory Performance on the Prediction of Progression From Mild Cognitive Impairment to Alzheimer Disease Dementia. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 29866588 DOI: 10.1016/j.jagp.2018.04.008  0.64
2018 Buckley RF, Mormino EC, Amariglio RE, Properzi MJ, Rabin JS, Lim YY, Papp KV, Jacobs HIL, Burnham S, Hanseeuw BJ, Doré V, Dobson A, Masters CL, Waller M, Rowe CC, ... ... Sperling RA, et al. Sex, amyloid, and APOE ε4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29803541 DOI: 10.1016/j.jalz.2018.04.010  0.48
2018 Rabin JS, Schultz AP, Hedden T, Viswanathan A, Marshall GA, Kilpatrick E, Klein H, Buckley RF, Yang HS, Properzi M, Rao V, Kirn DR, Papp KV, Rentz DM, Johnson KA, ... Sperling RA, et al. Interactive Associations of Vascular Risk and β-Amyloid Burden With Cognitive Decline in Clinically Normal Elderly Individuals: Findings From the Harvard Aging Brain Study. Jama Neurology. PMID 29799986 DOI: 10.1001/jamaneurol.2018.1123  0.48
2018 Hanseeuw BJ, Betensky RA, Mormino EC, Schultz AP, Sepulcre J, Becker JA, Jacobs HIL, Buckley RF, LaPoint MR, Vanini P, Donovan NJ, Chhatwal JP, Marshall GA, Papp KV, Amariglio RE, ... ... Sperling RA, et al. PET staging of amyloidosis using striatum. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29792874 DOI: 10.1016/j.jalz.2018.04.011  0.48
2018 Orlovsky I, Huijbers W, Hanseeuw BJ, Mormino EC, Hedden T, Buckley RF, LaPoint M, Rabin JS, Rentz DM, Johnson KA, Sperling RA, Papp KV. The relationship between recall of recently versus remotely encoded famous faces and amyloidosis in clinically normal older adults. Alzheimer's & Dementia (Amsterdam, Netherlands). 10: 121-129. PMID 29780861 DOI: 10.1016/j.dadm.2017.11.003  0.64
2018 Lee S, Zimmerman ME, Narkhede A, Nasrabady SE, Tosto G, Meier IB, Benzinger TLS, Marcus DS, Fagan AM, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, ... ... Sperling RA, et al. White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease. Plos One. 13: e0195838. PMID 29742105 DOI: 10.1371/journal.pone.0195838  0.44
2018 Lee CM, Jacobs HIL, Marquié M, Becker JA, Andrea NV, Jin DS, Schultz AP, Frosch MP, Gómez-Isla T, Sperling RA, Johnson KA. 18F-Flortaucipir Binding in Choroid Plexus: Related to Race and Hippocampus Signal. Journal of Alzheimer's Disease : Jad. 62: 1691-1702. PMID 29614677 DOI: 10.3233/JAD-170840  0.48
2018 Chhatwal JP, Schultz AP, Johnson KA, Hedden T, Jaimes S, Benzinger TLS, Jack C, Ances BM, Ringman JM, Marcus DS, Ghetti B, Farlow MR, Danek A, Levin J, Yakushev I, ... ... Sperling RA, et al. Preferential degradation of cognitive networks differentiates Alzheimer's disease from ageing. Brain : a Journal of Neurology. PMID 29522171 DOI: 10.1093/brain/awy053  0.48
2018 Quiroz YT, Sperling RA, Norton DJ, Baena A, Arboleda-Velasquez JF, Cosio D, Schultz A, Lapoint M, Guzman-Velez E, Miller JB, Kim LA, Chen K, Tariot PN, Lopera F, Reiman EM, et al. Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease. Jama Neurology. PMID 29435558 DOI: 10.1001/jamaneurol.2017.4907  0.44
2018 Rabin JS, Perea RD, Buckley RF, Neal TE, Buckner RL, Johnson KA, Sperling RA, Hedden T. Global White Matter Diffusion Characteristics Predict Longitudinal Cognitive Change Independently of Amyloid Status in Clinically Normal Older Adults. Cerebral Cortex (New York, N.Y. : 1991). PMID 29425267 DOI: 10.1093/cercor/bhy031  0.48
2018 Jacobs HIL, Hedden T, Schultz AP, Sepulcre J, Perea RD, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. Structural tract alterations predict downstream tau accumulation in amyloid-positive older individuals. Nature Neuroscience. PMID 29403032 DOI: 10.1038/s41593-018-0070-z  0.48
2018 Klinger RY, James OG, Borges-Neto S, Bisanar T, Li YJ, Qi W, Berger M, Terrando N, Newman MF, Doraiswamy PM, Mathew JP, Weiner MW, Aisen P, Weiner M, Aisen P, ... ... Sperling RA, ... ... Sperling RA, et al. 18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery. Anesthesiology. PMID 29389750 DOI: 10.1097/ALN.0000000000002103  0.44
2018 Donovan NJ, Locascio JJ, Marshall GA, Gatchel J, Hanseeuw BJ, Rentz DM, Johnson KA, Sperling RA. Longitudinal Association of Amyloid Beta and Anxious-Depressive Symptoms in Cognitively Normal Older Adults. The American Journal of Psychiatry. appiajp201717040442. PMID 29325447 DOI: 10.1176/appi.ajp.2017.17040442  0.44
2018 d'Oleire Uquillas F, Jacobs HIL, Hanseeuw B, Marshall GA, Properzi M, Schultz AP, LaPoint MR, Johnson KA, Sperling RA, Vannini P. Interactive versus additive relationships between regional cortical thinning and amyloid burden in predicting clinical decline in mild AD and MCI individuals. Neuroimage. Clinical. 17: 388-396. PMID 29159051 DOI: 10.1016/j.nicl.2017.10.034  0.64
2017 Papp KV, Rentz DM, Orlovsky I, Sperling RA, Mormino EC. Optimizing the preclinical Alzheimer's cognitive composite with semantic processing: The PACC5. Alzheimer's & Dementia (New York, N. Y.). 3: 668-677. PMID 29264389 DOI: 10.1016/j.trci.2017.10.004  0.44
2017 Marshall GA, Aghjayan SL, Dekhtyar M, Locascio JJ, Jethwani K, Amariglio RE, Johnson KA, Sperling RA, Rentz DM. Activities of daily living measured by the Harvard Automated Phone Task track with cognitive decline over time in non-demented elderly. The Journal of Prevention of Alzheimer's Disease. 4: 81-86. PMID 29124043 DOI: 10.14283/jpad.2017.10  0.44
2017 Jackson JD, Rentz DM, Aghjayan SL, Buckley RF, Meneide TF, Sperling RA, Amariglio RE. Subjective cognitive concerns are associated with objective memory performance in Caucasian but not African-American persons. Age and Ageing. 46: 988-993. PMID 29088363 DOI: 10.1093/ageing/afx077  0.44
2017 Dumurgier J, Hanseeuw BJ, Hatling FB, Judge KA, Schultz AP, Chhatwal JP, Blacker D, Sperling RA, Johnson KA, Hyman BT, Gómez-Isla T. Alzheimer's Disease Biomarkers and Future Decline in Cognitive Normal Older Adults. Journal of Alzheimer's Disease : Jad. PMID 29036824 DOI: 10.3233/JAD-170511  0.48
2017 Buckley RF, Hanseeuw B, Schultz AP, Vannini P, Aghjayan SL, Properzi MJ, Jackson JD, Mormino EC, Rentz DM, Sperling RA, Johnson KA, Amariglio RE. Region-Specific Association of Subjective Cognitive Decline With Tauopathy Independent of Global β-Amyloid Burden. Jama Neurology. PMID 28973551 DOI: 10.1001/jamaneurol.2017.2216  0.64
2017 Norton DJ, Amariglio R, Protas H, Chen K, Aguirre-Acevedo DC, Pulsifer B, Castrillon G, Tirado V, Munoz C, Tariot P, Langbaum JB, Reiman EM, Lopera F, Sperling RA, Quiroz YT. Subjective memory complaints in preclinical autosomal dominant Alzheimer disease. Neurology. PMID 28878053 DOI: 10.1212/WNL.0000000000004533  0.4
2017 Kinnunen KM, Cash DM, Poole T, Frost C, Benzinger TLS, Ahsan RL, Leung KK, Cardoso MJ, Modat M, Malone IB, Morris JC, Bateman RJ, Marcus DS, Goate A, Salloway S, ... ... Sperling RA, et al. Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial MRI study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28738187 DOI: 10.1016/j.jalz.2017.06.2268  0.44
2017 Gatchel JR, Donovan NJ, Locascio JJ, Schultz AP, Becker JA, Chhatwal J, Papp KV, Amariglio RE, Rentz DM, Blacker D, Sperling RA, Johnson KA, Marshall GA. Depressive Symptoms and Tau Accumulation in the Inferior Temporal Lobe and Entorhinal Cortex in Cognitively Normal Older Adults: A Pilot Study. Journal of Alzheimer's Disease : Jad. PMID 28697559 DOI: 10.3233/JAD-170001  0.48
2017 Vannini P, Hanseeuw B, Munro CE, Amariglio RE, Marshall GA, Rentz DM, Pascual-Leone A, Johnson KA, Sperling RA. Anosognosia for memory deficits in mild cognitive impairment: Insight into the neural mechanism using functional and molecular imaging. Neuroimage. Clinical. 15: 408-414. PMID 28616381 DOI: 10.1016/j.nicl.2017.05.020  0.64
2017 Buckley RF, Schultz AP, Hedden T, Papp KV, Hanseeuw BJ, Marshall G, Sepulcre J, Smith EE, Rentz DM, Johnson KA, Sperling RA, Chhatwal JP. Functional network integrity presages cognitive decline in preclinical Alzheimer disease. Neurology. PMID 28592457 DOI: 10.1212/WNL.0000000000004059  0.48
2017 Sepulcre J, Grothe MJ, Sabuncu M, Chhatwal J, Schultz AP, Hanseeuw B, El Fakhri G, Sperling R, Johnson KA. Hierarchical Organization of Tau and Amyloid Deposits in the Cerebral Cortex. Jama Neurology. PMID 28558094 DOI: 10.1001/jamaneurol.2017.0263  0.48
2017 LaPoint MR, Chhatwal JP, Sepulcre J, Johnson KA, Sperling RA, Schultz AP. The association between tau PET and retrospective cortical thinning in clinically normal elderly. Neuroimage. PMID 28545932 DOI: 10.1016/j.neuroimage.2017.05.049  0.48
2017 Dekhtyar M, Papp KV, Buckley R, Jacobs HIL, Schultz AP, Johnson KA, Sperling RA, Rentz DM. Neuroimaging Markers Associated with Maintenance of Optimal Memory Performance in Late-Life. Neuropsychologia. PMID 28472627 DOI: 10.1016/j.neuropsychologia.2017.04.037  0.48
2017 Gatchel JR, Donovan NJ, Locascio JJ, Becker JA, Rentz DM, Sperling RA, Johnson KA, Marshall GA. Regional 18F-Fluorodeoxyglucose Hypometabolism is Associated with Higher Apathy Scores Over Time in Early Alzheimer Disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 28410856 DOI: 10.1016/j.jagp.2016.12.017  0.44
2017 Vannini P, Amariglio R, Hanseeuw B, Johnson KA, McLaren DG, Chhatwal J, Pascual-Leone A, Rentz D, Sperling RA. Memory self-awareness in the preclinical and prodromal stages of Alzheimer's disease. Neuropsychologia. PMID 28385579 DOI: 10.1016/j.neuropsychologia.2017.04.002  0.64
2017 Vannini P, Hanseeuw B, Munro CE, Amariglio RE, Marshall GA, Rentz DM, Pascual-Leone A, Johnson KA, Sperling RA. Hippocampal hypometabolism in older adults with memory complaints and increased amyloid burden. Neurology. PMID 28381517 DOI: 10.1212/WNL.0000000000003889  0.64
2017 Sepulcre J, Sabuncu MR, Li Q, El Fakhri G, Sperling R, Johnson KA. Tau and Aβ proteins distinctively associate to functional network changes in the aging brain. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28366797 DOI: 10.1016/j.jalz.2017.02.011  0.44
2017 Schultz AP, Chhatwal JP, Hedden T, Mormino EC, Hanseeuw BJ, Sepulcre J, Huijbers W, LaPoint M, Buckley RF, Johnson KA, Sperling RA. Phases of hyper and hypo connectivity in the Default Mode and Salience networks track with amyloid and Tau in clinically normal individuals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28314821 DOI: 10.1523/JNEUROSCI.3263-16.2017  0.64
2017 Papp KV, Rentz DM, Mormino EC, Schultz AP, Amariglio RE, Quiroz Y, Johnson KA, Sperling RA. Cued memory decline in biomarker-defined preclinical Alzheimer disease. Neurology. PMID 28283594 DOI: 10.1212/WNL.0000000000003812  0.48
2017 Hanseeuw BJ, Betensky RA, Schultz AP, Papp KV, Mormino EC, Sepulcre J, Bark JS, Cosio DM, LaPoint M, Chhatwal JP, Rentz DM, Sperling RA, Johnson K. FDG metabolism associated with tau-amyloid interaction predicts memory decline. Annals of Neurology. PMID 28253546 DOI: 10.1002/ana.24910  0.48
2017 Mormino EC, Papp KV, Rentz DM, Donohue MC, Amariglio R, Quiroz YT, Chhatwal J, Marshall GA, Donovan N, Jackson J, Gatchel JR, Hanseeuw BJ, Schultz AP, Aisen PS, Johnson KA, ... Sperling RA, et al. Early and late change on the preclinical Alzheimer's cognitive composite in clinically normal older individuals with elevated β-amyloid. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28253478 DOI: 10.1016/j.jalz.2017.01.018  0.48
2016 Prčkovska V, Huijbers W, Schultz A, Ortiz-Teran L, Peña-Gomez C, Villoslada P, Johnson K, Sperling R, Sepulcre J. Epicenters of dynamic connectivity in the adaptation of the ventral visual system. Human Brain Mapping. PMID 28029725 DOI: 10.1002/hbm.23497  0.64
2016 Donovan NJ, Okereke OI, Vannini P, Amariglio RE, Rentz DM, Marshall GA, Johnson KA, Sperling RA. Association of Higher Cortical Amyloid Burden With Loneliness in Cognitively Normal Older Adults. Jama Psychiatry. PMID 27806159 DOI: 10.1001/jamapsychiatry.2016.2657  0.64
2016 Rentz DM, Mormino EC, Papp KV, Betensky RA, Sperling RA, Johnson KA. Cognitive resilience in clinical and preclinical Alzheimer's disease: the Association of Amyloid and Tau Burden on cognitive performance. Brain Imaging and Behavior. PMID 27738998 DOI: 10.1007/s11682-016-9640-4  0.44
2016 Aghjayan SL, Buckley RF, Vannini P, Rentz DM, Jackson JD, Sperling RA, Johnson KA, Amariglio RE. The influence of demographic factors on subjective cognitive concerns and beta-amyloid. International Psychogeriatrics. 1-8. PMID 27724996 DOI: 10.1017/S1041610216001502  0.64
2016 Albers AD, Asafu-Adjei J, Delaney MK, Kelly KE, Gomez-Isla T, Blacker D, Johnson KA, Sperling RA, Hyman BT, Betensky RA, Hastings L, Albers MW. Episodic Memory of Odors Stratifies Alzheimer Biomarkers in Normal Elderly. Annals of Neurology. PMID 27696605 DOI: 10.1002/ana.24792  0.44
2016 Gomperts SN, Locascio JJ, Makaretz SJ, Schultz A, Caso C, Vasdev N, Sperling R, Growdon JH, Dickerson BC, Johnson K. Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases. Jama Neurology. PMID 27654968 DOI: 10.1001/jamaneurol.2016.3338  0.4
2016 Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, ... ... Sperling RA, et al. Correction: Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. Plos One. 11: e0163669. PMID 27649320 DOI: 10.1371/journal.pone.0163669  0.44
2016 Huijbers W, Papp KV, LaPoint M, Wigman SE, Dagley A, Hedden T, Rentz DM, Schultz AP, Sperling RA. Age-Related Increases in Tip-of-the-tongue are Distinct from Decreases in Remembering Names: A Functional MRI Study. Cerebral Cortex (New York, N.Y. : 1991). PMID 27578492 DOI: 10.1093/cercor/bhw234  0.64
2016 Mormino EC, Papp KV, Rentz DM, Schultz AP, LaPoint M, Amariglio R, Hanseeuw B, Marshall GA, Hedden T, Johnson KA, Sperling RA. Heterogeneity in Suspected Non-Alzheimer Disease Pathophysiology Among Clinically Normal Older Individuals. Jama Neurology. PMID 27548655 DOI: 10.1001/jamaneurol.2016.2237  0.48
2016 Chan G, White CC, Winn PA, Cimpean M, Replogle JM, Glick LR, Cuerdon NE, Ryan KJ, Johnson KA, Schneider JA, Bennett DA, Chibnik LB, Sperling RA, De Jager PL, Bradshaw EM. Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci. Neurology. Genetics. 2: e90. PMID 27504496 DOI: 10.1212/NXG.0000000000000090  0.44
2016 Chhatwal JP, Schultz AP, Marshall GA, Boot B, Gomez-Isla T, Dumurgier J, LaPoint M, Scherzer C, Roe AD, Hyman BT, Sperling RA, Johnson KA. Temporal T807 binding correlates with CSF tau and phospho-tau in normal elderly. Neurology. PMID 27473132 DOI: 10.1212/WNL.0000000000003050  0.48
2016 Hanseeuw BJ, Schultz AP, Betensky RA, Sperling RA, Johnson KA. Decreased hippocampal metabolism in high-amyloid mild cognitive impairment. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27421609 DOI: 10.1016/j.jalz.2016.06.2357  0.48
2016 Sepulcre J, Schultz AP, Sabuncu M, Gomez-Isla T, Chhatwal J, Becker A, Sperling R, Johnson KA. In Vivo Tau, Amyloid, and Gray Matter Profiles in the Aging Brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7364-74. PMID 27413148 DOI: 10.1523/JNEUROSCI.0639-16.2016  0.48
2016 Jack CR, Bennett DA, Blennow K, Carrillo MC, Feldman HH, Frisoni GB, Hampel H, Jagust WJ, Johnson KA, Knopman DS, Petersen RC, Scheltens P, Sperling RA, Dubois B. A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers. Neurology. PMID 27371494 DOI: 10.1212/WNL.0000000000002923  0.44
2016 Hsu DC, Mormino EC, Schultz AP, Amariglio RE, Donovan NJ, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Lower Late-Life Body-Mass Index is Associated with Higher Cortical Amyloid Burden in Clinically Normal Elderly. Journal of Alzheimer's Disease : Jad. PMID 27340843 DOI: 10.3233/JAD-150987  0.48
2016 Fotiadis P, van Rooden S, van der Grond J, Schultz A, Martinez-Ramirez S, Auriel E, Reijmer Y, van Opstal AM, Ayres A, Schwab KM, Alzheimer's Disease Neuroimaging Initiative Adni, Hedden T, Rosand J, Viswanathan A, Wermer M, ... ... Sperling RA, et al. Cortical atrophy in patients with cerebral amyloid angiopathy: a case-control study. The Lancet. Neurology. PMID 27180034 DOI: 10.1016/S1474-4422(16)30030-8  0.48
2016 Donovan NJ, Wu Q, Rentz DM, Sperling RA, Marshall GA, Glymour MM. Loneliness, depression and cognitive function in older U.S. adults. International Journal of Geriatric Psychiatry. PMID 27162047 DOI: 10.1002/gps.4495  0.44
2016 Weninger S, Carrillo MC, Dunn B, Aisen PS, Bateman RJ, Kotz JD, Langbaum JB, Mills SL, Reiman EM, Sperling R, Santacruz AM, Tariot PN, Welsh-Bohmer KA. Collaboration for Alzheimer's Prevention: Principles to guide data and sample sharing in preclinical Alzheimer's disease trials. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 12: 631-2. PMID 27157073 DOI: 10.1016/j.jalz.2016.04.001  0.4
2016 Rieckmann A, Van Dijk KR, Sperling RA, Johnson KA, Buckner RL, Hedden T. Accelerated decline in white matter integrity in clinically normal individuals at risk for Alzheimer's disease. Neurobiology of Aging. 42: 177-88. PMID 27143434 DOI: 10.1016/j.neurobiolaging.2016.03.016  0.48
2016 Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, ... ... Sperling RA, et al. Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. Plos One. 11: e0152082. PMID 27010959 DOI: 10.1371/journal.pone.0152082  0.44
2016 Rentz DM, Dekhtyar M, Sherman J, Burnham S, Blacker D, Aghjayan SL, Papp KV, Amariglio RE, Schembri A, Chenhall T, Maruff P, Aisen P, Hyman BT, Sperling RA. The Feasibility of At-Home iPad Cognitive Testing For Use in Clinical Trials. The Journal of Prevention of Alzheimer's Disease. 3: 8-12. PMID 26998469 DOI: 10.14283/jpad.2015.78  0.44
2016 Maye JE, Betensky RA, Gidicsin CM, Locascio J, Becker JA, Pepin L, Carmasin J, Rentz DM, Marshall GA, Blacker D, Sperling RA, Johnson KA. Maternal dementia age at onset in relation to amyloid burden in non-demented elderly offspring. Neurobiology of Aging. 40: 61-7. PMID 26973104 DOI: 10.1016/j.neurobiolaging.2015.12.013  0.44
2016 Greve DN, Salat DH, Bowen SL, Izquierdo-Garcia D, Schultz AP, Catana C, Becker JA, Svarer C, Knudsen G, Sperling RA, Johnson KA. Different partial volume correction methods lead to different conclusions: An (18)F-FDG-PET study of aging. Neuroimage. PMID 26915497 DOI: 10.1016/j.neuroimage.2016.02.042  0.48
2015 Marshall GA, Dekhtyar M, Bruno JM, Jethwani K, Amariglio RE, Johnson KA, Sperling RA, Rentz DM. The Harvard Automated Phone Task: new performance-based activities of daily living tests for early Alzheimer's disease. The Journal of Prevention of Alzheimer's Disease. 2: 242-253. PMID 26665121 DOI: 10.14283/jpad.2015.72  0.44
2015 Malishkevich A, Marshall GA, Schultz AP, Sperling RA, Aharon-Peretz J, Gozes I. Blood-Borne Activity-Dependent Neuroprotective Protein (ADNP) is Correlated with Premorbid Intelligence, Clinical Stage, and Alzheimer's Disease Biomarkers. Journal of Alzheimer's Disease : Jad. PMID 26639975 DOI: 10.3233/JAD-150799  0.48
2015 Papp KV, Mormino EC, Amariglio RE, Munro C, Dagley A, Schultz AP, Johnson KA, Sperling RA, Rentz DM. Biomarker Validation of a Decline in Semantic Processing in Preclinical Alzheimer's Disease. Neuropsychology. PMID 26595826 DOI: 10.1037/neu0000246  0.48
2015 Rieckmann A, Hedden T, Younger AP, Sperling RA, Johnson KA, Buckner RL. Dopamine transporter availability in clinically normal aging is associated with individual differences in white matter integrity. Human Brain Mapping. PMID 26542307 DOI: 10.1002/hbm.23054  0.48
2015 Johnson KA, Schultz A, Betensky RA, Becker JA, Sepulcre J, Rentz D, Mormino E, Chhatwal J, Amariglio R, Papp K, Marshall G, Albers M, Mauro S, Pepin L, Alverio J, ... ... Sperling R, et al. Tau PET imaging in aging and early Alzheimer's disease. Annals of Neurology. PMID 26505746 DOI: 10.1002/ana.24546  0.44
2015 Reiman EM, Langbaum JB, Tariot PN, Lopera F, Bateman RJ, Morris JC, Sperling RA, Aisen PS, Roses AD, Welsh-Bohmer KA, Carrillo MC, Weninger S. CAP-advancing the evaluation of preclinical Alzheimer disease treatments. Nature Reviews. Neurology. PMID 26416539 DOI: 10.1038/nrneurol.2015.177  0.4
2015 Chan G, White CC, Winn PA, Cimpean M, Replogle JM, Glick LR, Cuerdon NE, Ryan KJ, Johnson KA, Schneider JA, Bennett DA, Chibnik LB, Sperling RA, Bradshaw EM, De Jager PL. CD33 modulates TREM2: convergence of Alzheimer loci. Nature Neuroscience. PMID 26414614 DOI: 10.1038/nn.4126  0.44
2015 Rabin LA, Smart CM, Crane PK, Amariglio RE, Berman LM, Boada M, Buckley RF, Chételat G, Dubois B, Ellis KA, Gifford KA, Jefferson AL, Jessen F, Katz MJ, Lipton RB, ... ... Sperling RA, et al. Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures used Across 19 International Research Studies. Journal of Alzheimer's Disease : Jad. PMID 26402085 DOI: 10.3233/JAD-150154  0.44
2015 Guercio BJ, Donovan NJ, Munro CE, Aghjayan SL, Wigman SE, Locascio JJ, Amariglio RE, Rentz DM, Johnson KA, Sperling RA, Marshall GA. The Apathy Evaluation Scale: A Comparison of Subject, Informant, and Clinician Report in Cognitively Normal Elderly and Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. 47: 421-32. PMID 26401564 DOI: 10.3233/JAD-150146  0.44
2015 Hyman BT, Growdon JH, Albers MW, Buckner RL, Chhatwal J, Gomez-Isla MT, Haass C, Hudry E, Jack CR, Johnson KA, Khachaturian ZS, Kim DY, Martin JB, Nitsch RM, Rosen BR, ... ... Sperling RA, et al. Massachusetts Alzheimer's Disease Research Center: Progress and challenges. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26297855 DOI: 10.1016/j.jalz.2015.06.1887  0.44
2015 Sperling RA, Amariglio RE, Marshall GA, Rentz DM. Establishing Clinical Relevance in Preclinical Alzheimer's Disease. The Journal of Prevention of Alzheimer's Disease. 2: 85-87. PMID 26247003 DOI: 10.14283/jpad.2015.56  0.44
2015 Toledo JB, Zetterberg H, van Harten AC, Glodzik L, Martinez-Lage P, Bocchio-Chiavetto L, Rami L, Hansson O, Sperling R, Engelborghs S, Osorio RS, Vanderstichele H, Vandijck M, Hampel H, Teipl S, et al. Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects. Brain : a Journal of Neurology. 138: 2701-15. PMID 26220940 DOI: 10.1093/brain/awv199  0.44
2015 Auriel E, Westover MB, Bianchi MT, Reijmer Y, Martinez-Ramirez S, Ni J, Van Etten E, Frosch MP, Fotiadis P, Schwab K, Vashkevich A, Boulouis G, Younger AP, Johnson KA, Sperling RA, et al. Estimating Total Cerebral Microinfarct Burden From Diffusion-Weighted Imaging. Stroke; a Journal of Cerebral Circulation. PMID 26159796 DOI: 10.1161/STROKEAHA.115.009208  0.48
2015 Quiroz YT, Schultz AP, Chen K, Protas HD, Brickhouse M, Fleisher AS, Langbaum JB, Thiyyagura P, Fagan AM, Shah AR, Muniz M, Arboleda-Velasquez JF, Munoz C, Garcia G, Acosta-Baena N, ... ... Sperling RA, et al. Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease: A Cross-Sectional Study. Jama Neurology. PMID 26121081 DOI: 10.1001/jamaneurol.2015.1099  0.96
2015 Doody RS, Raman R, Sperling RA, Seimers E, Sethuraman G, Mohs R, Farlow M, Iwatsubo T, Vellas B, Sun X, Ernstrom K, Thomas RG, Aisen PS. Peripheral and central effects of γ-secretase inhibition by semagacestat in Alzheimer's disease. Alzheimer's Research & Therapy. 7: 36. PMID 26064192 DOI: 10.1186/s13195-015-0121-6  0.96
2015 Gidicsin CM, Maye JE, Locascio JJ, Pepin LC, Philiossaint M, Becker JA, Younger AP, Dekhtyar M, Schultz AP, Amariglio RE, Marshall GA, Rentz DM, Hedden T, Sperling RA, Johnson KA. Cognitive activity relates to cognitive performance but not to Alzheimer disease biomarkers. Neurology. 85: 48-55. PMID 26062627 DOI: 10.1212/WNL.0000000000001704  0.96
2015 Amariglio RE, Mormino EC, Pietras AC, Marshall GA, Vannini P, Johnson KA, Sperling RA, Rentz DM. Subjective cognitive concerns, amyloid-β, and neurodegeneration in clinically normal elderly. Neurology. 85: 56-62. PMID 26048028 DOI: 10.1212/WNL.0000000000001712  0.96
2015 Reijmer YD, Schultz AP, Leemans A, O'Sullivan MJ, Gurol ME, Sperling R, Greenberg SM, Viswanathan A, Hedden T. Decoupling of structural and functional brain connectivity in older adults with white matter hyperintensities. Neuroimage. 117: 222-9. PMID 26025290 DOI: 10.1016/j.neuroimage.2015.05.054  0.96
2015 Marshall GA, Zoller AS, Lorius N, Amariglio RE, Locascio JJ, Johnson KA, Sperling RA, Rentz DM, For The Alzheimer's Disease Neuroimaging Initiative EY. Functional Activities Questionnaire Items that Best Discriminate and Predict Progression from Clinically Normal to Mild Cognitive Impairment. Current Alzheimer Research. 12: 493-502. PMID 26017560  0.96
2015 Papp KV, Amariglio RE, Mormino EC, Hedden T, Dekhytar M, Johnson KA, Sperling RA, Rentz DM. Free and cued memory in relation to biomarker-defined abnormalities in clinically normal older adults and those at risk for Alzheimer's disease. Neuropsychologia. 73: 169-75. PMID 26002757 DOI: 10.1016/j.neuropsychologia.2015.04.034  0.96
2015 Harkins K, Sankar P, Sperling R, Grill JD, Green RC, Johnson KA, Healy M, Karlawish J. Development of a process to disclose amyloid imaging results to cognitively normal older adult research participants. Alzheimer's Research & Therapy. 7: 26. PMID 25969699 DOI: 10.1186/s13195-015-0112-7  0.96
2015 Growdon ME, Schultz AP, Dagley AS, Amariglio RE, Hedden T, Rentz DM, Johnson KA, Sperling RA, Albers MW, Marshall GA. Odor identification and Alzheimer disease biomarkers in clinically normal elderly. Neurology. 84: 2153-60. PMID 25934852 DOI: 10.1212/WNL.0000000000001614  0.96
2015 Munro CE, Donovan NJ, Guercio BJ, Wigman SE, Schultz AP, Amariglio RE, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Neuropsychiatric Symptoms and Functional Connectivity in Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. PMID 25854929 DOI: 10.3233/JAD-150017  0.48
2015 Dagley A, LaPoint M, Huijbers W, Hedden T, McLaren DG, Chatwal JP, Papp KV, Amariglio RE, Blacker D, Rentz DM, Johnson KA, Sperling RA, Schultz AP. Harvard Aging Brain Study: Dataset and accessibility. Neuroimage. PMID 25843019 DOI: 10.1016/j.neuroimage.2015.03.069  0.96
2015 Shaw EE, Schultz AP, Sperling RA, Hedden T. Functional Connectivity in Multiple Cortical Networks Is Associated with Performance Across Cognitive Domains in Older Adults. Brain Connectivity. PMID 25827242 DOI: 10.1089/brain.2014.0327  0.48
2015 Mattsson N, Insel PS, Donohue M, Jagust W, Sperling R, Aisen P, Weiner MW. Predicting Reduction of Cerebrospinal Fluid β-Amyloid 42 in Cognitively Healthy Controls. Jama Neurology. 72: 554-60. PMID 25775167 DOI: 10.1001/jamaneurol.2014.4530  0.96
2015 Guercio BJ, Donovan NJ, Ward A, Schultz A, Lorius N, Amariglio RE, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Apathy is associated with lower inferior temporal cortical thickness in mild cognitive impairment and normal elderly individuals. The Journal of Neuropsychiatry and Clinical Neurosciences. 27: e22-7. PMID 25716491 DOI: 10.1176/appi.neuropsych.13060141  0.96
2015 Perry D, Sperling R, Katz R, Berry D, Dilts D, Hanna D, Salloway S, Trojanowski JQ, Bountra C, Krams M, Luthman J, Potkin S, Gribkoff V, Temple R, Wang Y, et al. Building a roadmap for developing combination therapies for Alzheimer's disease. Expert Review of Neurotherapeutics. 15: 327-33. PMID 25708309 DOI: 10.1586/14737175.2015.996551  0.96
2015 Amariglio RE, Donohue MC, Marshall GA, Rentz DM, Salmon DP, Ferris SH, Karantzoulis S, Aisen PS, Sperling RA. Tracking early decline in cognitive function in older individuals at risk for Alzheimer disease dementia: the Alzheimer's Disease Cooperative Study Cognitive Function Instrument. Jama Neurology. 72: 446-54. PMID 25706191 DOI: 10.1001/jamaneurol.2014.3375  0.96
2015 Donovan NJ, Hsu DC, Dagley AS, Schultz AP, Amariglio RE, Mormino EC, Okereke OI, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Depressive Symptoms and Biomarkers of Alzheimer's Disease in Cognitively Normal Older Adults. Journal of Alzheimer's Disease : Jad. PMID 25697700 DOI: 10.3233/JAD-142940  0.96
2015 Huijbers W, Mormino EC, Schultz AP, Wigman S, Ward AM, Larvie M, Amariglio RE, Marshall GA, Rentz DM, Johnson KA, Sperling RA. Amyloid-β deposition in mild cognitive impairment is associated with increased hippocampal activity, atrophy and clinical progression. Brain : a Journal of Neurology. 138: 1023-35. PMID 25678559 DOI: 10.1093/brain/awv007  0.96
2015 Replogle JM, Chan G, White CC, Raj T, Winn PA, Evans DA, Sperling RA, Chibnik LB, Bradshaw EM, Schneider JA, Bennett DA, De Jager PL. A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology. Annals of Neurology. 77: 469-77. PMID 25545807 DOI: 10.1002/ana.24337  0.96
2015 Stephenson D, Perry D, Bens C, Bain LJ, Berry D, Krams M, Sperling R, Dilts D, Luthman J, Hanna D, McKew J, Temple R, Fields FO, Salloway S, Katz R. Charting a path toward combination therapy for Alzheimer's disease. Expert Review of Neurotherapeutics. 15: 107-13. PMID 25540951 DOI: 10.1586/14737175.2015.995168  0.96
2015 Su Y, Blazey TM, Snyder AZ, Raichle ME, Marcus DS, Ances BM, Bateman RJ, Cairns NJ, Aldea P, Cash L, Christensen JJ, Friedrichsen K, Hornbeck RC, Farrar AM, Owen CJ, ... ... Sperling RA, et al. Partial volume correction in quantitative amyloid imaging. Neuroimage. 107: 55-64. PMID 25485714 DOI: 10.1016/j.neuroimage.2014.11.058  0.44
2015 Ward AM, Mormino EC, Huijbers W, Schultz AP, Hedden T, Sperling RA. Relationships between default-mode network connectivity, medial temporal lobe structure, and age-related memory deficits. Neurobiology of Aging. 36: 265-72. PMID 25113793 DOI: 10.1016/j.neurobiolaging.2014.06.028  0.96
2015 Lorius N, Locascio JJ, Rentz DM, Johnson KA, Sperling RA, Viswanathan A, Marshall GA. Vascular disease and risk factors are associated with cognitive decline in the alzheimer disease spectrum. Alzheimer Disease and Associated Disorders. 29: 18-25. PMID 24787033 DOI: 10.1097/WAD.0000000000000043  0.96
2015 Guercio BJ, Donovan NJ, Munro CE, Aghjayan SL, Wigman SE, Locascio JJ, Amariglio RE, Rentz DM, Johnson KA, Sperling RA, Marshall GA. The Apathy Evaluation Scale: A Comparison of Subject, Informant, and Clinician Report in Cognitively Normal Elderly and Mild Cognitive Impairment Journal of Alzheimer's Disease. 47: 421-432. DOI: 10.3233/JAD-150146  0.96
2015 Donovan NJ, Hsu DC, Dagley AS, Schultz AP, Amariglio RE, Mormino EC, Okereke OI, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Depressive symptoms and biomarkers of alzheimer’s disease in cognitively normal older adults Handbook of Depression in Alzheimer's Disease. 205-215. DOI: 10.3233/978-1-61499-542-5-205  0.48
2015 Toledo JB, Zetterberg H, Van Harten AC, Glodzik L, Martinez-Lage P, Bocchio-Chiavetto L, Rami L, Hansson O, Sperling R, Engelborghs S, Osorio RS, Vanderstichele H, Vandijck M, Hampel H, Teipl S, et al. Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects Brain. 138: 2701-2715. DOI: 10.1093/brain/awv199  0.44
2015 Quiroz YT, Schultz AP, Chen K, Protas HD, Brickhouse M, Fleisher AS, Langbaum JB, Thiyyagura P, Fagan AM, Shah AR, Muniz M, Arboleda-Velasquez JF, Munoz C, Garcia G, Acosta-Baena N, ... ... Sperling RA, et al. Brain imaging and blood biomarker abnormalities in children with autosomal dominant Alzheimer disease a cross-sectional study Jama Neurology. 72: 912-919.  0.96
2014 Sperling R, Mormino E, Johnson K. The evolution of preclinical Alzheimer's disease: implications for prevention trials. Neuron. 84: 608-22. PMID 25442939 DOI: 10.1016/j.neuron.2014.10.038  0.96
2014 Fargo KN, Aisen P, Albert M, Au R, Corrada MM, DeKosky S, Drachman D, Fillit H, Gitlin L, Haas M, Herrup K, Kawas C, Khachaturian AS, Khachaturian ZS, ... ... Sperling RA, et al. 2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S430-52. PMID 25341459 DOI: 10.1016/j.jalz.2014.08.103  0.96
2014 Hedden T, Schultz AP, Rieckmann A, Mormino EC, Johnson KA, Sperling RA, Buckner RL. Multiple Brain Markers are Linked to Age-Related Variation in Cognition. Cerebral Cortex (New York, N.Y. : 1991). PMID 25316342 DOI: 10.1093/cercor/bhu238  0.48
2014 Marshall GA, Zoller AS, Kelly KE, Amariglio RE, Locascio JJ, Johnson KA, Sperling RA, Rentz DM, For The Alzheimer's Disease Neuroimaging Initiative. Everyday cognition scale items that best discriminate between and predict progression from clinically normal to mild cognitive impairment. Current Alzheimer Research. 11: 853-61. PMID 25274110  0.96
2014 Samieri C, Proust-Lima C, M Glymour M, Okereke OI, Amariglio RE, Sperling RA, Rentz DM, Grodstein F. Subjective cognitive concerns, episodic memory, and the APOE ε4 allele. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 752-759.e1. PMID 25256133 DOI: 10.1016/j.jalz.2014.06.012  0.96
2014 Mormino EC, Betensky RA, Hedden T, Schultz AP, Amariglio RE, Rentz DM, Johnson KA, Sperling RA. Synergistic effect of β-amyloid and neurodegeneration on cognitive decline in clinically normal individuals. Jama Neurology. 71: 1379-85. PMID 25222039 DOI: 10.1001/jamaneurol.2014.2031  0.96
2014 Zoller AS, Gaal IM, Royer CA, Locascio JJ, Amariglio RE, Blacker D, Okereke OI, Johnson KA, Sperling RA, Rentz DM, Marshall GA. SIST-M-IR activities of daily living items that best discriminate clinically normal elderly from those with mild cognitive impairment. Current Alzheimer Research. 11: 785-91. PMID 25212917  0.96
2014 Schultz AP, Chhatwal JP, Huijbers W, Hedden T, van Dijk KR, McLaren DG, Ward AM, Wigman S, Sperling RA. Template based rotation: a method for functional connectivity analysis with a priori templates. Neuroimage. 102: 620-36. PMID 25150630 DOI: 10.1016/j.neuroimage.2014.08.022  0.96
2014 Thomas JB, Brier MR, Bateman RJ, Snyder AZ, Benzinger TL, Xiong C, Raichle M, Holtzman DM, Sperling RA, Mayeux R, Ghetti B, Ringman JM, Salloway S, McDade E, Rossor MN, et al. Functional connectivity in autosomal dominant and late-onset Alzheimer disease. Jama Neurology. 71: 1111-22. PMID 25069482 DOI: 10.1001/jamaneurol.2014.1654  0.96
2014 Ryman DC, Acosta-Baena N, Aisen PS, Bird T, Danek A, Fox NC, Goate A, Frommelt P, Ghetti B, Langbaum JB, Lopera F, Martins R, Masters CL, Mayeux RP, McDade E, ... ... Sperling R, et al. Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis. Neurology. 83: 253-60. PMID 24928124 DOI: 10.1212/WNL.0000000000000596  0.96
2014 Roy K, Pepin LC, Philiossaint M, Lorius N, Becker JA, Locascio JJ, Rentz DM, Sperling RA, Johnson KA, Marshall GA. Regional fluorodeoxyglucose metabolism and instrumental activities of daily living across the Alzheimer's disease spectrum. Journal of Alzheimer's Disease : Jad. 42: 291-300. PMID 24898635 DOI: 10.3233/JAD-131796  0.44
2014 Donohue MC, Sperling RA, Salmon DP, Rentz DM, Raman R, Thomas RG, Weiner M, Aisen PS. The preclinical Alzheimer cognitive composite: measuring amyloid-related decline. Jama Neurology. 71: 961-70. PMID 24886908 DOI: 10.1001/jamaneurol.2014.803  0.96
2014 McLaren DG, Sperling RA, Atri A. Flexible modulation of network connectivity related to cognition in Alzheimer's disease. Neuroimage. 100: 544-57. PMID 24852459 DOI: 10.1016/j.neuroimage.2014.05.032  0.96
2014 Papp KV, Amariglio RE, Dekhtyar M, Roy K, Wigman S, Bamfo R, Sherman J, Sperling RA, Rentz DM. Development of a psychometrically equivalent short form of the Face-Name Associative Memory Exam for use along the early Alzheimer's disease trajectory. The Clinical Neuropsychologist. 28: 771-85. PMID 24815535 DOI: 10.1080/13854046.2014.911351  0.96
2014 Jessen F, Amariglio RE, van Boxtel M, Breteler M, Ceccaldi M, Chételat G, Dubois B, Dufouil C, Ellis KA, van der Flier WM, Glodzik L, van Harten AC, de Leon MJ, McHugh P, Mielke MM, ... ... Sperling RA, et al. A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 844-52. PMID 24798886 DOI: 10.1016/j.jalz.2014.01.001  0.96
2014 Feldman HH, Haas M, Gandy S, Schoepp DD, Cross AJ, Mayeux R, Sperling RA, Fillit H, van de Hoef DL, Dougal S, Nye JS. Alzheimer's disease research and development: a call for a new research roadmap. Annals of the New York Academy of Sciences. 1313: 1-16. PMID 24754377 DOI: 10.1111/nyas.12424  0.96
2014 Mormino EC, Betensky RA, Hedden T, Schultz AP, Ward A, Huijbers W, Rentz DM, Johnson KA, Sperling RA. Amyloid and APOE ε4 interact to influence short-term decline in preclinical Alzheimer disease. Neurology. 82: 1760-7. PMID 24748674 DOI: 10.1212/WNL.0000000000000431  0.96
2014 Salloway S, Sperling R, Brashear HR. Phase 3 trials of solanezumab and bapineuzumab for Alzheimer's disease. The New England Journal of Medicine. 370: 1460. PMID 24724181  0.96
2014 Huijbers W, Mormino EC, Wigman SE, Ward AM, Vannini P, McLaren DG, Becker JA, Schultz AP, Hedden T, Johnson KA, Sperling RA. Amyloid deposition is linked to aberrant entorhinal activity among cognitively normal older adults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5200-10. PMID 24719099 DOI: 10.1523/JNEUROSCI.3579-13.2014  0.96
2014 Marder TJ, Flores VL, Bolo NR, Hoogenboom WS, Simonson DC, Jacobson AM, Foote SE, Shenton ME, Sperling RA, Musen G. Task-induced brain activity patterns in type 2 diabetes: a potential biomarker for cognitive decline. Diabetes. 63: 3112-9. PMID 24705405 DOI: 10.2337/db13-1783  0.96
2014 Donovan NJ, Amariglio RE, Zoller AS, Rudel RK, Gomez-Isla T, Blacker D, Hyman BT, Locascio JJ, Johnson KA, Sperling RA, Marshall GA, Rentz DM. Subjective cognitive concerns and neuropsychiatric predictors of progression to the early clinical stages of Alzheimer disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 22: 1642-51. PMID 24698445 DOI: 10.1016/j.jagp.2014.02.007  0.96
2014 Marshall GA, Lorius N, Locascio JJ, Hyman BT, Rentz DM, Johnson KA, Sperling RA. Regional cortical thinning and cerebrospinal biomarkers predict worsening daily functioning across the Alzheimer's disease spectrum. Journal of Alzheimer's Disease : Jad. 41: 719-28. PMID 24685624 DOI: 10.3233/JAD-132768  0.44
2014 Sperling RA, Rentz DM, Johnson KA, Karlawish J, Donohue M, Salmon DP, Aisen P. The A4 study: stopping AD before symptoms begin? Science Translational Medicine. 6: 228fs13. PMID 24648338 DOI: 10.1126/scitranslmed.3007941  0.96
2014 Doraiswamy PM, Sperling RA, Johnson K, Reiman EM, Wong TZ, Sabbagh MN, Sadowsky CH, Fleisher AS, Carpenter A, Joshi AD, Lu M, Grundman M, Mintun MA, Skovronsky DM, Pontecorvo MJ, et al. Florbetapir F 18 amyloid PET and 36-month cognitive decline: a prospective multicenter study. Molecular Psychiatry. 19: 1044-51. PMID 24614494 DOI: 10.1038/mp.2014.9  0.96
2014 Fagan AM, Xiong C, Jasielec MS, Bateman RJ, Goate AM, Benzinger TL, Ghetti B, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Salloway S, Schofield PR, Sperling RA, et al. Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease. Science Translational Medicine. 6: 226ra30. PMID 24598588 DOI: 10.1126/scitranslmed.3007901  0.96
2014 Serrano-Pozo A, Qian J, Monsell SE, Blacker D, Gómez-Isla T, Betensky RA, Growdon JH, Johnson KA, Frosch MP, Sperling RA, Hyman BT. Mild to moderate Alzheimer dementia with insufficient neuropathological changes. Annals of Neurology. 75: 597-601. PMID 24585367 DOI: 10.1002/ana.24125  0.96
2014 Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, et al. Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease. The New England Journal of Medicine. 370: 322-33. PMID 24450891 DOI: 10.1056/NEJMoa1304839  0.96
2014 Donovan NJ, Wadsworth LP, Lorius N, Locascio JJ, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Regional cortical thinning predicts worsening apathy and hallucinations across the Alzheimer disease spectrum. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 22: 1168-79. PMID 23890751 DOI: 10.1016/j.jagp.2013.03.006  0.96
2014 Ward AM, Schultz AP, Huijbers W, Van Dijk KR, Hedden T, Sperling RA. The parahippocampal gyrus links the default-mode cortical network with the medial temporal lobe memory system. Human Brain Mapping. 35: 1061-73. PMID 23404748 DOI: 10.1002/hbm.22234  0.96
2014 Salloway S, Sperling R, Brashear HR. Dr. Salloway and colleagues reply New England Journal of Medicine. 370: 1460. DOI: 10.1056/NEJMc1402193  0.96
2013 Rentz DM, Parra Rodriguez MA, Amariglio R, Stern Y, Sperling R, Ferris S. Promising developments in neuropsychological approaches for the detection of preclinical Alzheimer's disease: a selective review. Alzheimer's Research & Therapy. 5: 58. PMID 24257331 DOI: 10.1186/alzrt222  0.96
2013 Marshall GA, Donovan NJ, Lorius N, Gidicsin CM, Maye J, Pepin LC, Becker JA, Amariglio RE, Rentz DM, Sperling RA, Johnson KA. Apathy is associated with increased amyloid burden in mild cognitive impairment. The Journal of Neuropsychiatry and Clinical Neurosciences. 25: 302-7. PMID 24247857 DOI: 10.1176/appi.neuropsych.12060156  0.96
2013 Benzinger TL, Blazey T, Jack CR, Koeppe RA, Su Y, Xiong C, Raichle ME, Snyder AZ, Ances BM, Bateman RJ, Cairns NJ, Fagan AM, Goate A, Marcus DS, Aisen PS, ... ... Sperling RA, et al. Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: E4502-9. PMID 24194552 DOI: 10.1073/pnas.1317918110  0.96
2013 Ward AM, McLaren DG, Schultz AP, Chhatwal J, Boot BP, Hedden T, Sperling RA. Daytime sleepiness is associated with decreased default mode network connectivity in both young and cognitively intact elderly subjects. Sleep. 36: 1609-15. PMID 24179292 DOI: 10.5665/sleep.3108  0.96
2013 Santiago JA, Scherzer CR, Potashkin JA, Hyman BT, Ivinson AJ, Trisini-Lipsanopoulos A, Dhima K, Bayer S, Lockhart KC, Yi T, Liao Z, Hoesing AN, Duong K, Roderick S, Sudarsky LR, ... ... Sperling R, et al. Specific splice variants are associated with Parkinson's disease Movement Disorders. 28: 1724-1727. PMID 24108702 DOI: 10.1002/mds.25635  0.96
2013 Cash DM, Ridgway GR, Liang Y, Ryan NS, Kinnunen KM, Yeatman T, Malone IB, Benzinger TL, Jack CR, Thompson PM, Ghetti BF, Saykin AJ, Masters CL, Ringman JM, Salloway SP, ... ... Sperling RA, et al. The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study. Neurology. 81: 1425-33. PMID 24049139 DOI: 10.1212/WNL.0b013e3182a841c6  0.96
2013 Mills SM, Mallmann J, Santacruz AM, Fuqua A, Carril M, Aisen PS, Althage MC, Belyew S, Benzinger TL, Brooks WS, Buckles VD, Cairns NJ, Clifford D, Danek A, Fagan AM, ... ... Sperling RA, et al. Preclinical trials in autosomal dominant AD: implementation of the DIAN-TU trial. Revue Neurologique. 169: 737-43. PMID 24016464 DOI: 10.1016/j.neurol.2013.07.017  0.96
2013 Johnson KA, Sperling RA, Sepulcre J. Functional connectivity in Alzheimer's disease: measurement and meaning. Biological Psychiatry. 74: 318-9. PMID 23932342 DOI: 10.1016/j.biopsych.2013.07.010  0.96
2013 Frisoni GB, Bocchetta M, Chételat G, Rabinovici GD, de Leon MJ, Kaye J, Reiman EM, Scheltens P, Barkhof F, Black SE, Brooks DJ, Carrillo MC, Fox NC, Herholz K, Nordberg A, ... ... Sperling RA, et al. Imaging markers for Alzheimer disease: which vs how. Neurology. 81: 487-500. PMID 23897875 DOI: 10.1212/WNL.0b013e31829d86e8  0.96
2013 Chhatwal JP, Schultz AP, Johnson K, Benzinger TL, Jack C, Ances BM, Sullivan CA, Salloway SP, Ringman JM, Koeppe RA, Marcus DS, Thompson P, Saykin AJ, Correia S, Schofield PR, ... ... Sperling RA, et al. Impaired default network functional connectivity in autosomal dominant Alzheimer disease. Neurology. 81: 736-44. PMID 23884042 DOI: 10.1212/WNL.0b013e3182a1aafe  0.96
2013 Salmon DP, Ferris SH, Thomas RG, Sano M, Cummings JL, Sperling RA, Petersen RC, Aisen PS. Age and apolipoprotein E genotype influence rate of cognitive decline in nondemented elderly. Neuropsychology. 27: 391-401. PMID 23876113 DOI: 10.1037/a0032707  0.96
2013 Vellas B, Carrillo MC, Sampaio C, Brashear HR, Siemers E, Hampel H, Schneider LS, Weiner M, Doody R, Khachaturian Z, Cedarbaum J, Grundman M, Broich K, Giacobini E, Dubois B, ... Sperling R, et al. Designing drug trials for Alzheimer's disease: what we have learned from the release of the phase III antibody trials: a report from the EU/US/CTAD Task Force. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 438-44. PMID 23809364 DOI: 10.1016/j.jalz.2013.03.007  0.96
2013 Sepulcre J, Sabuncu MR, Becker A, Sperling R, Johnson KA. In vivo characterization of the early states of the amyloid-beta network. Brain : a Journal of Neurology. 136: 2239-52. PMID 23801740 DOI: 10.1093/brain/awt146  0.96
2013 Bradshaw EM, Chibnik LB, Keenan BT, Ottoboni L, Raj T, Tang A, Rosenkrantz LL, Imboywa S, Lee M, Von Korff A, Morris MC, Evans DA, Johnson K, Sperling RA, et al. CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology. Nature Neuroscience. 16: 848-50. PMID 23708142 DOI: 10.1038/nn.3435  0.96
2013 Barakos J, Sperling R, Salloway S, Jack C, Gass A, Fiebach JB, Tampieri D, Melançon D, Miaux Y, Rippon G, Black R, Lu Y, Brashear HR, Arrighi HM, Morris KA, et al. MR imaging features of amyloid-related imaging abnormalities. Ajnr. American Journal of Neuroradiology. 34: 1958-65. PMID 23578674 DOI: 10.3174/ajnr.A3500  0.96
2013 Sperling R, Johnson K. Biomarkers of Alzheimer disease: current and future applications to diagnostic criteria. Continuum (Minneapolis, Minn.). 19: 325-38. PMID 23558480 DOI: 10.1212/01.CON.0000429181.60095.99  0.96
2013 Werring DJ, Sperling R. Inflammatory cerebral amyloid angiopathy and amyloid-modifying therapies: variations on the same ARIA? Annals of Neurology. 73: 439-41. PMID 23526685 DOI: 10.1002/ana.23891  0.96
2013 Carrillo MC, Brashear HR, Logovinsky V, Ryan JM, Feldman HH, Siemers ER, Abushakra S, Hartley DM, Petersen RC, Khachaturian AS, Sperling RA. Can we prevent Alzheimer's disease? Secondary "prevention" trials in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 123-131.e1. PMID 23411394 DOI: 10.1016/j.jalz.2012.12.004  0.96
2013 Huijbers W, Schultz AP, Vannini P, McLaren DG, Wigman SE, Ward AM, Hedden T, Sperling RA. The encoding/retrieval flip: interactions between memory performance and memory stage and relationship to intrinsic cortical networks. Journal of Cognitive Neuroscience. 25: 1163-79. PMID 23384193 DOI: 10.1162/jocn_a_00366  0.96
2013 Yang T, Hong S, O'Malley T, Sperling RA, Walsh DM, Selkoe DJ. New ELISAs with high specificity for soluble oligomers of amyloid β-protein detect natural Aβ oligomers in human brain but not CSF. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 99-112. PMID 23375565 DOI: 10.1016/j.jalz.2012.11.005  0.96
2013 Johnson KA, Sperling RA, Gidicsin CM, Carmasin JS, Maye JE, Coleman RE, Reiman EM, Sabbagh MN, Sadowsky CH, Fleisher AS, Murali Doraiswamy P, Carpenter AP, Clark CM, Joshi AD, Lu M, et al. Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: S72-83. PMID 23375563 DOI: 10.1016/j.jalz.2012.10.007  0.96
2013 Sperling RA, Karlawish J, Johnson KA. Preclinical Alzheimer disease-the challenges ahead. Nature Reviews. Neurology. 9: 54-8. PMID 23183885 DOI: 10.1038/nrneurol.2012.241  0.96
2013 Quiroz YT, Stern CE, Reiman EM, Brickhouse M, Ruiz A, Sperling RA, Lopera F, Dickerson BC. Cortical atrophy in presymptomatic Alzheimer's disease presenilin 1 mutation carriers. Journal of Neurology, Neurosurgery, and Psychiatry. 84: 556-61. PMID 23134660 DOI: 10.1136/jnnp-2012-303299  0.96
2013 Desikan RS, McEvoy LK, Holland D, Thompson WK, Brewer JB, Aisen PS, Andreassen OA, Hyman BT, Sperling RA, Dale AM. Apolipoprotein E epsilon4 does not modulate amyloid-β-associated neurodegeneration in preclinical Alzheimer disease. Ajnr. American Journal of Neuroradiology. 34: 505-10. PMID 22976236 DOI: 10.3174/ajnr.A3267  0.96
2013 Sperling RA, Johnson KA, Doraiswamy PM, Reiman EM, Fleisher AS, Sabbagh MN, Sadowsky CH, Carpenter A, Davis MD, Lu M, Flitter M, Joshi AD, Clark CM, Grundman M, Mintun MA, et al. Amyloid deposition detected with florbetapir F 18 ((18)F-AV-45) is related to lower episodic memory performance in clinically normal older individuals. Neurobiology of Aging. 34: 822-31. PMID 22878163 DOI: 10.1016/j.neurobiolaging.2012.06.014  0.96
2013 Fleisher AS, Chen K, Liu X, Ayutyanont N, Roontiva A, Thiyyagura P, Protas H, Joshi AD, Sabbagh M, Sadowsky CH, Sperling RA, Clark CM, Mintun MA, Pontecorvo MJ, Coleman RE, et al. Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease. Neurobiology of Aging. 34: 1-12. PMID 22633529 DOI: 10.1016/j.neurobiolaging.2012.04.017  0.96
2013 Vannini P, Hedden T, Huijbers W, Ward A, Johnson KA, Sperling RA. The ups and downs of the posteromedial cortex: age- and amyloid-related functional alterations of the encoding/retrieval flip in cognitively normal older adults. Cerebral Cortex (New York, N.Y. : 1991). 23: 1317-28. PMID 22586140 DOI: 10.1093/cercor/bhs108  0.96
2013 Vannini P, Hedden T, Sullivan C, Sperling RA. Differential functional response in the posteromedial cortices and hippocampus to stimulus repetition during successful memory encoding. Human Brain Mapping. 34: 1568-78. PMID 22344847 DOI: 10.1002/hbm.22011  0.96
2012 Marshall GA, Amariglio RE, Sperling RA, Rentz DM. Activities of daily living: where do they fit in the diagnosis of Alzheimer's disease? Neurodegenerative Disease Management. 2: 483-491. PMID 23585777 DOI: 10.2217/nmt.12.55  0.44
2012 Hedden T, Mormino EC, Amariglio RE, Younger AP, Schultz AP, Becker JA, Buckner RL, Johnson KA, Sperling RA, Rentz DM. Cognitive profile of amyloid burden and white matter hyperintensities in cognitively normal older adults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16233-42. PMID 23152607 DOI: 10.1523/JNEUROSCI.2462-12.2012  0.96
2012 Reiman EM, Quiroz YT, Fleisher AS, Chen K, Velez-Pardo C, Jimenez-Del-Rio M, Fagan AM, Shah AR, Alvarez S, Arbelaez A, Giraldo M, Acosta-Baena N, Sperling RA, Dickerson B, Stern CE, et al. Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study. The Lancet. Neurology. 11: 1048-56. PMID 23137948 DOI: 10.1016/S1474-4422(12)70228-4  0.96
2012 Huijbers W, Vannini P, Sperling RA, C M P, Cabeza R, Daselaar SM. Explaining the encoding/retrieval flip: memory-related deactivations and activations in the posteromedial cortex. Neuropsychologia. 50: 3764-74. PMID 22982484 DOI: 10.1016/j.neuropsychologia.2012.08.021  0.96
2012 Naylor MD, Karlawish JH, Arnold SE, Khachaturian AS, Khachaturian ZS, Lee VM, Baumgart M, Banerjee S, Beck C, Blennow K, Brookmeyer R, Brunden KR, Buckwalter KC, Comer M, Covinsky K, ... ... Sperling RA, et al. Advancing Alzheimer's disease diagnosis, treatment, and care: recommendations from the Ware Invitational Summit. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 445-52. PMID 22959699 DOI: 10.1016/j.jalz.2012.08.001  0.96
2012 Amariglio RE, Becker JA, Carmasin J, Wadsworth LP, Lorius N, Sullivan C, Maye JE, Gidicsin C, Pepin LC, Sperling RA, Johnson KA, Rentz DM. Subjective cognitive complaints and amyloid burden in cognitively normal older individuals. Neuropsychologia. 50: 2880-6. PMID 22940426 DOI: 10.1016/j.neuropsychologia.2012.08.011  0.96
2012 Wadsworth LP, Lorius N, Donovan NJ, Locascio JJ, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Neuropsychiatric symptoms and global functional impairment along the Alzheimer's continuum. Dementia and Geriatric Cognitive Disorders. 34: 96-111. PMID 22922821 DOI: 10.1159/000342119  0.96
2012 Chhatwal JP, Sperling RA. Functional MRI of mnemonic networks across the spectrum of normal aging, mild cognitive impairment, and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 31: S155-67. PMID 22890098 DOI: 10.3233/JAD-2012-120730  0.96
2012 Doraiswamy PM, Sperling RA, Coleman RE, Johnson KA, Reiman EM, Davis MD, Grundman M, Sabbagh MN, Sadowsky CH, Fleisher AS, Carpenter A, Clark CM, Joshi AD, Mintun MA, Skovronsky DM, et al. Amyloid-β assessed by florbetapir F 18 PET and 18-month cognitive decline: a multicenter study. Neurology. 79: 1636-44. PMID 22786606 DOI: 10.1212/WNL.0b013e3182661f74  0.96
2012 Bateman RJ, Xiong C, Benzinger TL, Fagan AM, Goate A, Fox NC, Marcus DS, Cairns NJ, Xie X, Blazey TM, Holtzman DM, Santacruz A, Buckles V, Oliver A, Moulder K, ... ... Sperling RA, et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. The New England Journal of Medicine. 367: 795-804. PMID 22784036 DOI: 10.1056/NEJMoa1202753  0.96
2012 Amariglio RE, Frishe K, Olson LE, Wadsworth LP, Lorius N, Sperling RA, Rentz DM. Validation of the Face Name Associative Memory Exam in cognitively normal older individuals. Journal of Clinical and Experimental Neuropsychology. 34: 580-7. PMID 22765048 DOI: 10.1080/13803395.2012.666230  0.96
2012 DeCarli C, Kawas C, Morrison JH, Reuter-Lorenz PA, Sperling RA, Wright CB. Session II: Mechanisms of age-related cognitive change and targets for intervention: neural circuits, networks, and plasticity. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 747-53. PMID 22570135 DOI: 10.1093/gerona/gls111  0.96
2012 Desikan RS, McEvoy LK, Thompson WK, Holland D, Brewer JB, Aisen PS, Sperling RA, Dale AM. Amyloid-β--associated clinical decline occurs only in the presence of elevated P-tau. Archives of Neurology. 69: 709-13. PMID 22529247 DOI: 10.1001/archneurol.2011.3354  0.96
2012 Johnson KA, Fox NC, Sperling RA, Klunk WE. Brain imaging in Alzheimer disease. Cold Spring Harbor Perspectives in Medicine. 2: a006213. PMID 22474610 DOI: 10.1101/cshperspect.a006213  0.96
2012 McLaren DG, Sreenivasan A, Diamond EL, Mitchell MB, Van Dijk KR, Deluca AN, O'Brien JL, Rentz DM, Sperling RA, Atri A. Tracking cognitive change over 24 weeks with longitudinal functional magnetic resonance imaging in Alzheimer's disease. Neuro-Degenerative Diseases. 9: 176-86. PMID 22456451 DOI: 10.1159/000335876  0.96
2012 Sperling R, Salloway S, Brooks DJ, Tampieri D, Barakos J, Fox NC, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Lieberburg I, Arrighi HM, Morris KA, Lu Y, Liu E, et al. Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis. The Lancet. Neurology. 11: 241-9. PMID 22305802 DOI: 10.1016/S1474-4422(12)70015-7  0.96
2012 Sperling R, Johnson K. To sleep, perchance to delay dementia. Archives of Neurology. 69: 118-20. PMID 22232352 DOI: 10.1001/archneurol.2011.1901  0.96
2012 Villemagne VL, Klunk WE, Mathis CA, Rowe CC, Brooks DJ, Hyman BT, Ikonomovic MD, Ishii K, Jack CR, Jagust WJ, Johnson KA, Koeppe RA, Lowe VJ, Masters CL, Montine TJ, ... ... Sperling RA, et al. Aβ Imaging: feasible, pertinent, and vital to progress in Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging. 39: 209-19. PMID 22218879 DOI: 10.1007/s00259-011-2045-0  0.96
2012 Sperling RA, Johnson KA. Dementia: new criteria but no new treatments. The Lancet. Neurology. 11: 4-5. PMID 22172609 DOI: 10.1016/S1474-4422(11)70272-1  0.96
2012 Sabuncu MR, Buckner RL, Smoller JW, Lee PH, Fischl B, Sperling RA. The association between a polygenic Alzheimer score and cortical thickness in clinically normal subjects. Cerebral Cortex (New York, N.Y. : 1991). 22: 2653-61. PMID 22169231 DOI: 10.1093/cercor/bhr348  0.96
2012 Hurko O, Black SE, Doody R, Doraiswamy PM, Gamst A, Kaye J, Obisesan TO, Rusinek H, Scharre D, Sperling R, Weiner MW, Green RC. The ADNI Publication Policy: commensurate recognition of critical contributors who are not authors. Neuroimage. 59: 4196-200. PMID 22100665 DOI: 10.1016/j.neuroimage.2011.10.085  0.96
2012 Hedden T, Van Dijk KR, Shire EH, Sperling RA, Johnson KA, Buckner RL. Failure to modulate attentional control in advanced aging linked to white matter pathology. Cerebral Cortex (New York, N.Y. : 1991). 22: 1038-51. PMID 21765181 DOI: 10.1093/cercor/bhr172  0.96
2012 Vannini P, Hedden T, Becker JA, Sullivan C, Putcha D, Rentz D, Johnson KA, Sperling RA. Age and amyloid-related alterations in default network habituation to stimulus repetition. Neurobiology of Aging. 33: 1237-52. PMID 21334099 DOI: 10.1016/j.neurobiolaging.2011.01.003  0.96
2012 Mckhann GM, Albert MS, Sperling RA. Changing diagnostic concepts of Alzheimer's disease Advances in Biological Psychiatry. 28: 115-121. DOI: 10.1159/000335402  0.96
2012 Teipel S, Sperling RA, Skudlarski P, Jack C, Hampel H, Fellgiebel A, Herholz K. MRI- and PET-based imaging markers for the diagnosis of Alzheimer's disease Advances in Biological Psychiatry. 28: 80-114. DOI: 10.1159/000335393  0.96
2012 Schneider JA, Montine TJ, Sperling RA, Bennett DA. Neuropathological basis of Alzheimer's disease and Alzheimer's disease diagnosis Advances in Biological Psychiatry. 28: 49-70. DOI: 10.1159/000335384  0.96
2011 Silverberg NB, Ryan LM, Carrillo MC, Sperling R, Petersen RC, Posner HB, Snyder PJ, Hilsabeck R, Gallagher M, Raber J, Rizzo A, Possin K, King J, Kaye J, Ott BR, et al. Assessment of cognition in early dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: e60-e76. PMID 23559893 DOI: 10.1016/j.jalz.2011.05.001  0.72
2011 Reiman EM, McKhann GM, Albert MS, Sperling RA, Petersen RC, Blacker D. Clinical impact of updated diagnostic and research criteria for Alzheimer's disease. The Journal of Clinical Psychiatry. 72: e37. PMID 22244033 DOI: 10.4088/JCP.10087tx2c  0.96
2011 Holtzman DM, Goate A, Kelly J, Sperling R. Mapping the road forward in Alzheimer's disease. Science Translational Medicine. 3: 114ps48. PMID 22190237 DOI: 10.1126/scitranslmed.3003529  0.96
2011 Sperling RA, Jack CR, Aisen PS. Testing the right target and right drug at the right stage. Science Translational Medicine. 3: 111cm33. PMID 22133718 DOI: 10.1126/scitranslmed.3002609  0.96
2011 Putcha D, Brickhouse M, O'Keefe K, Sullivan C, Rentz D, Marshall G, Dickerson B, Sperling R. Hippocampal hyperactivation associated with cortical thinning in Alzheimer's disease signature regions in non-demented elderly adults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17680-8. PMID 22131428 DOI: 10.1523/JNEUROSCI.4740-11.2011  0.96
2011 Sperling R. Potential of functional MRI as a biomarker in early Alzheimer's disease. Neurobiology of Aging. 32: S37-43. PMID 22078171 DOI: 10.1016/j.neurobiolaging.2011.09.009  0.96
2011 Reiman EM, McKhann GM, Albert MS, Sperling RA, Petersen RC, Blacker D. Alzheimer's disease: implications of the updated diagnostic and research criteria. The Journal of Clinical Psychiatry. 72: 1190-6. PMID 21951985 DOI: 10.4088/JCP.10087co1c  0.96
2011 Amariglio RE, Townsend MK, Grodstein F, Sperling RA, Rentz DM. Specific subjective memory complaints in older persons may indicate poor cognitive function. Journal of the American Geriatrics Society. 59: 1612-7. PMID 21919893 DOI: 10.1111/j.1532-5415.2011.03543.x  0.96
2011 Salloway S, Sperling R, Keren R, Porsteinsson AP, van Dyck CH, Tariot PN, Gilman S, Arnold D, Abushakra S, Hernandez C, Crans G, Liang E, Quinn G, Bairu M, Pastrak A, et al. A phase 2 randomized trial of ELND005, scyllo-inositol, in mild to moderate Alzheimer disease. Neurology. 77: 1253-62. PMID 21917766 DOI: 10.1212/WNL.0b013e3182309fa5  0.96
2011 Sabuncu MR, Desikan RS, Sepulcre J, Yeo BT, Liu H, Schmansky NJ, Reuter M, Weiner MW, Buckner RL, Sperling RA, Fischl B. The dynamics of cortical and hippocampal atrophy in Alzheimer disease. Archives of Neurology. 68: 1040-8. PMID 21825241 DOI: 10.1001/archneurol.2011.167  0.96
2011 Jack CR, Barkhof F, Bernstein MA, Cantillon M, Cole PE, Decarli C, Dubois B, Duchesne S, Fox NC, Frisoni GB, Hampel H, Hill DL, Johnson K, Mangin JF, Scheltens P, ... ... Sperling R, et al. Steps to standardization and validation of hippocampal volumetry as a biomarker in clinical trials and diagnostic criterion for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 474-485.e4. PMID 21784356 DOI: 10.1016/j.jalz.2011.04.007  0.96
2011 Sperling RA, Jack CR, Black SE, Frosch MP, Greenberg SM, Hyman BT, Scheltens P, Carrillo MC, Thies W, Bednar MM, Black RS, Brashear HR, Grundman M, Siemers ER, Feldman HH, et al. Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: recommendations from the Alzheimer's Association Research Roundtable Workgroup. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 367-85. PMID 21784348 DOI: 10.1016/j.jalz.2011.05.2351  0.96
2011 Marshall GA, Olson LE, Frey MT, Maye J, Becker JA, Rentz DM, Sperling RA, Johnson KA. Instrumental activities of daily living impairment is associated with increased amyloid burden. Dementia and Geriatric Cognitive Disorders. 31: 443-50. PMID 21778725 DOI: 10.1159/000329543  0.96
2011 Ewers M, Sperling RA, Klunk WE, Weiner MW, Hampel H. Neuroimaging markers for the prediction and early diagnosis of Alzheimer's disease dementia. Trends in Neurosciences. 34: 430-42. PMID 21696834 DOI: 10.1016/j.tins.2011.05.005  0.96
2011 Rentz DM, Amariglio RE, Becker JA, Frey M, Olson LE, Frishe K, Carmasin J, Maye JE, Johnson KA, Sperling RA. Face-name associative memory performance is related to amyloid burden in normal elderly. Neuropsychologia. 49: 2776-83. PMID 21689670 DOI: 10.1016/j.neuropsychologia.2011.06.006  0.96
2011 Marshall GA, Rentz DM, Frey MT, Locascio JJ, Johnson KA, Sperling RA. Executive function and instrumental activities of daily living in mild cognitive impairment and Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 300-8. PMID 21575871 DOI: 10.1016/j.jalz.2010.04.005  0.96
2011 Atri A, O'Brien JL, Sreenivasan A, Rastegar S, Salisbury S, DeLuca AN, O'Keefe KM, LaViolette PS, Rentz DM, Locascio JJ, Sperling RA. Test-retest reliability of memory task functional magnetic resonance imaging in Alzheimer disease clinical trials. Archives of Neurology. 68: 599-606. PMID 21555634 DOI: 10.1001/archneurol.2011.94  0.96
2011 Sperling RA, Aisen PS, Beckett LA, Bennett DA, Craft S, Fagan AM, Iwatsubo T, Jack CR, Kaye J, Montine TJ, Park DC, Reiman EM, Rowe CC, Siemers E, Stern Y, et al. Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 280-92. PMID 21514248 DOI: 10.1016/j.jalz.2011.03.003  0.96
2011 Jack CR, Albert MS, Knopman DS, McKhann GM, Sperling RA, Carrillo MC, Thies B, Phelps CH. Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 257-62. PMID 21514247 DOI: 10.1016/j.jalz.2011.03.004  0.96
2011 Dickerson BC, Stoub TR, Shah RC, Sperling RA, Killiany RJ, Albert MS, Hyman BT, Blacker D, Detoledo-Morrell L. Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults. Neurology. 76: 1395-402. PMID 21490323 DOI: 10.1212/WNL.0b013e3182166e96  0.96
2011 Drzezga A, Becker JA, Van Dijk KR, Sreenivasan A, Talukdar T, Sullivan C, Schultz AP, Sepulcre J, Putcha D, Greve D, Johnson KA, Sperling RA. Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden. Brain : a Journal of Neurology. 134: 1635-46. PMID 21490054 DOI: 10.1093/brain/awr066  0.96
2011 Becker JA, Hedden T, Carmasin J, Maye J, Rentz DM, Putcha D, Fischl B, Greve DN, Marshall GA, Salloway S, Marks D, Buckner RL, Sperling RA, Johnson KA. Amyloid-β associated cortical thinning in clinically normal elderly. Annals of Neurology. 69: 1032-42. PMID 21437929 DOI: 10.1002/ana.22333  0.96
2011 Khachaturian ZS, Petersen RC, Snyder PJ, Khachaturian AS, Aisen P, de Leon M, Greenberg BD, Kukull W, Maruff P, Sperling RA, Stern Y, Touchon J, Vellas B, Andrieu S, Weiner MW, et al. Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 127-32. PMID 21414553 DOI: 10.1016/j.jalz.2011.02.005  0.96
2011 Yang W, Lui RL, Gao JH, Chan TF, Yau ST, Sperling RA, Huang X. Independent component analysis-based classification of Alzheimer's disease MRI data. Journal of Alzheimer's Disease : Jad. 24: 775-83. PMID 21321398 DOI: 10.3233/JAD-2011-101371  0.96
2011 Putcha D, O'Keefe K, LaViolette P, O'Brien J, Greve D, Rentz DM, Locascio J, Atri A, Sperling R. Reliability of functional magnetic resonance imaging associative encoding memory paradigms in non-demented elderly adults. Human Brain Mapping. 32: 2027-44. PMID 21259385 DOI: 10.1002/hbm.21166  0.96
2011 Van Dijk KR, Sperling RA. Defaulting on the default network: increased risk for dementia. Neurology. 76: 498-500. PMID 21228298 DOI: 10.1212/WNL.0b013e31820af975  0.96
2011 Bateman RJ, Aisen PS, De Strooper B, Fox NC, Lemere CA, Ringman JM, Salloway S, Sperling RA, Windisch M, Xiong C. Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease. Alzheimer's Research & Therapy. 3: 1. PMID 21211070 DOI: 10.1186/alzrt59  0.96
2011 Pihlajamäki M, O'Keefe K, O'Brien J, Blacker D, Sperling RA. Failure of repetition suppression and memory encoding in aging and Alzheimer's disease. Brain Imaging and Behavior. 5: 36-44. PMID 21161449 DOI: 10.1007/s11682-010-9110-3  0.96
2011 Vannini P, O'Brien J, O'Keefe K, Pihlajamäki M, Laviolette P, Sperling RA. What goes down must come up: role of the posteromedial cortices in encoding and retrieval. Cerebral Cortex (New York, N.Y. : 1991). 21: 22-34. PMID 20363808 DOI: 10.1093/cercor/bhq051  0.96
2010 Desikan RS, Sabuncu MR, Schmansky NJ, Reuter M, Cabral HJ, Hess CP, Weiner MW, Biffi A, Anderson CD, Rosand J, Salat DH, Kemper TL, Dale AM, Sperling RA, Fischl B, et al. Selective disruption of the cerebral neocortex in Alzheimer's disease. Plos One. 5: e12853. PMID 20886094 DOI: 10.1371/journal.pone.0012853  0.96
2010 Sperling R, Johnson K. Pro: Can biomarkers be gold standards in Alzheimer's disease? Alzheimer's Research & Therapy. 2: 17. PMID 20587006 DOI: 10.1186/alzrt41  0.96
2010 Black RS, Sperling RA, Safirstein B, Motter RN, Pallay A, Nichols A, Grundman M. A single ascending dose study of bapineuzumab in patients with Alzheimer disease. Alzheimer Disease and Associated Disorders. 24: 198-203. PMID 20505438 DOI: 10.1097/WAD.0b013e3181c53b00  0.96
2010 O'Brien JL, O'Keefe KM, LaViolette PS, DeLuca AN, Blacker D, Dickerson BC, Sperling RA. Longitudinal fMRI in elderly reveals loss of hippocampal activation with clinical decline. Neurology. 74: 1969-76. PMID 20463288 DOI: 10.1212/WNL.0b013e3181e3966e  0.96
2010 Rentz DM, Locascio JJ, Becker JA, Moran EK, Eng E, Buckner RL, Sperling RA, Johnson KA. Cognition, reserve, and amyloid deposition in normal aging. Annals of Neurology. 67: 353-64. PMID 20373347 DOI: 10.1002/ana.21904  0.96
2010 Wang L, Laviolette P, O'Keefe K, Putcha D, Bakkour A, Van Dijk KR, Pihlajamäki M, Dickerson BC, Sperling RA. Intrinsic connectivity between the hippocampus and posteromedial cortex predicts memory performance in cognitively intact older individuals. Neuroimage. 51: 910-7. PMID 20188183 DOI: 10.1016/j.neuroimage.2010.02.046  0.96
2010 Wang L, Negreira A, LaViolette P, Bakkour A, Sperling RA, Dickerson BC. Intrinsic interhemispheric hippocampal functional connectivity predicts individual differences in memory performance ability. Hippocampus. 20: 345-51. PMID 20087893 DOI: 10.1002/hipo.20771  0.96
2010 Sperling RA, Dickerson BC, Pihlajamaki M, Vannini P, LaViolette PS, Vitolo OV, Hedden T, Becker JA, Rentz DM, Selkoe DJ, Johnson KA. Functional alterations in memory networks in early Alzheimer's disease. Neuromolecular Medicine. 12: 27-43. PMID 20069392 DOI: 10.1007/s12017-009-8109-7  0.96
2010 Pihlajamäki M, O' Keefe K, Bertram L, Tanzi RE, Dickerson BC, Blacker D, Albert MS, Sperling RA. Evidence of altered posteromedial cortical FMRI activity in subjects at risk for Alzheimer disease. Alzheimer Disease and Associated Disorders. 24: 28-36. PMID 19571734 DOI: 10.1097/WAD.0b013e3181a785c9  0.96
2009 Salloway S, Sperling R, Gilman S, Fox NC, Blennow K, Raskind M, Sabbagh M, Honig LS, Doody R, van Dyck CH, Mulnard R, Barakos J, Gregg KM, Liu E, Lieberburg I, et al. A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease. Neurology. 73: 2061-70. PMID 19923550 DOI: 10.1212/WNL.0b013e3181c67808  0.96
2009 Pihlajamäki M, Sperling RA. Functional MRI assessment of task-induced deactivation of the default mode network in Alzheimer's disease and at-risk older individuals. Behavioural Neurology. 21: 77-91. PMID 19847047 DOI: 10.3233/BEN-2009-0231  0.96
2009 Dickerson BC, Sperling RA. Large-scale functional brain network abnormalities in Alzheimer's disease: insights from functional neuroimaging. Behavioural Neurology. 21: 63-75. PMID 19847046 DOI: 10.3233/BEN-2009-0227  0.96
2009 Hedden T, Van Dijk KR, Becker JA, Mehta A, Sperling RA, Johnson KA, Buckner RL. Disruption of functional connectivity in clinically normal older adults harboring amyloid burden. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12686-94. PMID 19812343 DOI: 10.1523/JNEUROSCI.3189-09.2009  0.96
2009 Sperling RA, Laviolette PS, O'Keefe K, O'Brien J, Rentz DM, Pihlajamaki M, Marshall G, Hyman BT, Selkoe DJ, Hedden T, Buckner RL, Becker JA, Johnson KA. Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron. 63: 178-88. PMID 19640477 DOI: 10.1016/j.neuron.2009.07.003  0.96
2009 Carrillo MC, Blackwell A, Hampel H, Lindborg J, Sperling R, Schenk D, Sevigny JJ, Ferris S, Bennett DA, Craft S, Hsu T, Klunk W. Early risk assessment for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 5: 182-96. PMID 19328456 DOI: 10.1016/j.jalz.2009.01.019  0.96
2009 Chua EF, Schacter DL, Sperling RA. Neural basis for recognition confidence in younger and older adults. Psychology and Aging. 24: 139-53. PMID 19290745 DOI: 10.1037/a0014029  0.96
2009 Buckner RL, Sepulcre J, Talukdar T, Krienen FM, Liu H, Hedden T, Andrews-Hanna JR, Sperling RA, Johnson KA. Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1860-73. PMID 19211893 DOI: 10.1523/JNEUROSCI.5062-08.2009  0.96
2009 Chua EF, Schacter DL, Sperling RA. Neural correlates of metamemory: a comparison of feeling-of-knowing and retrospective confidence judgments. Journal of Cognitive Neuroscience. 21: 1751-65. PMID 18823230 DOI: 10.1162/jocn.2009.21123  0.96
2009 Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, Grodstein F, Wright CI, Blacker D, Rosas HD, Sperling RA, Atri A, Growdon JH, Hyman BT, Morris JC, et al. The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals. Cerebral Cortex (New York, N.Y. : 1991). 19: 497-510. PMID 18632739 DOI: 10.1093/cercor/bhn113  0.96
2008 Pihlajamäki M, DePeau KM, Blacker D, Sperling RA. Impaired medial temporal repetition suppression is related to failure of parietal deactivation in Alzheimer disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 16: 283-92. PMID 18378553 DOI: 10.1097/JGP.0b013e318162a0a9  0.96
2008 Miller SL, Celone K, DePeau K, Diamond E, Dickerson BC, Rentz D, Pihlajamäki M, Sperling RA. Age-related memory impairment associated with loss of parietal deactivation but preserved hippocampal activation. Proceedings of the National Academy of Sciences of the United States of America. 105: 2181-6. PMID 18238903 DOI: 10.1073/pnas.0706818105  0.96
2008 Dickerson BC, Sperling RA. Functional abnormalities of the medial temporal lobe memory system in mild cognitive impairment and Alzheimer's disease: insights from functional MRI studies. Neuropsychologia. 46: 1624-35. PMID 18206188 DOI: 10.1016/j.neuropsychologia.2007.11.030  0.96
2008 Miller SL, Fenstermacher E, Bates J, Blacker D, Sperling RA, Dickerson BC. Hippocampal activation in adults with mild cognitive impairment predicts subsequent cognitive decline. Journal of Neurology, Neurosurgery, and Psychiatry. 79: 630-5. PMID 17846109 DOI: 10.1136/jnnp.2007.124149  0.96
2007 Dickerson BC, Sperling RA, Hyman BT, Albert MS, Blacker D. Clinical prediction of Alzheimer disease dementia across the spectrum of mild cognitive impairment. Archives of General Psychiatry. 64: 1443-50. PMID 18056553 DOI: 10.1001/archpsyc.64.12.1443  0.96
2007 Diamond EL, Miller S, Dickerson BC, Atri A, DePeau K, Fenstermacher E, Pihlajamäki M, Celone K, Salisbury S, Gregas M, Rentz D, Sperling RA. Relationship of fMRI activation to clinical trial memory measures in Alzheimer disease. Neurology. 69: 1331-41. PMID 17893294 DOI: 10.1212/01.wnl.0000277292.37292.69  0.96
2007 Rentz DM, Huh TJ, Sardinha LM, Moran EK, Becker JA, Daffner KR, Sperling RA, Johnson KA. Intelligence quotient-adjusted memory impairment is associated with abnormal single photon emission computed tomography perfusion. Journal of the International Neuropsychological Society : Jins. 13: 821-31. PMID 17697413 DOI: 10.1017/S1355617707071056  0.96
2007 Glanz BI, Holland CM, Gauthier SA, Amunwa EL, Liptak Z, Houtchens MK, Sperling RA, Khoury SJ, Guttmann CR, Weiner HL. Cognitive dysfunction in patients with clinically isolated syndromes or newly diagnosed multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 13: 1004-10. PMID 17623735 DOI: 10.1177/1352458507077943  0.96
2007 Dickerson BC, Miller SL, Greve DN, Dale AM, Albert MS, Schacter DL, Sperling RA. Prefrontal-hippocampal-fusiform activity during encoding predicts intraindividual differences in free recall ability: an event-related functional-anatomic MRI study. Hippocampus. 17: 1060-70. PMID 17604356 DOI: 10.1002/hipo.20338  0.96
2007 Chua EF, Schacter DL, Rand-Giovannetti E, Sperling RA. Evidence for a specific role of the anterior hippocampal region in successful associative encoding. Hippocampus. 17: 1071-80. PMID 17604351 DOI: 10.1002/hipo.20340  0.96
2007 Sperling R. Functional MRI studies of associative encoding in normal aging, mild cognitive impairment, and Alzheimer's disease. Annals of the New York Academy of Sciences. 1097: 146-55. PMID 17413017 DOI: 10.1196/annals.1379.009  0.96
2007 Chappell AS, Gonzales C, Williams J, Witte MM, Mohs RC, Sperling R. AMPA potentiator treatment of cognitive deficits in Alzheimer disease. Neurology. 68: 1008-12. PMID 17389305 DOI: 10.1212/01.wnl.0000260240.46070.7c  0.96
2006 Alsop DC, Fearing MA, Johnson K, Sperling R, Fong TG, Inouye SK. The role of neuroimaging in elucidating delirium pathophysiology. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 61: 1287-93. PMID 17234822  0.96
2006 Salmon DP, Cummings JL, Jin S, Sano M, Sperling RA, Zamrini E, Petersen RC, Edland SD, Thal LJ, Ferris SH. ADCS Prevention Instrument Project: development of a brief verbal memory test for primary prevention clinical trials. Alzheimer Disease and Associated Disorders. 20: S139-46. PMID 17135807 DOI: 10.1097/01.wad.0000213871.40300.68  0.96
2006 Celone KA, Calhoun VD, Dickerson BC, Atri A, Chua EF, Miller SL, DePeau K, Rentz DM, Selkoe DJ, Blacker D, Albert MS, Sperling RA. Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10222-31. PMID 17021177 DOI: 10.1523/JNEUROSCI.2250-06.2006  0.96
2006 Rentz DM, Sardinha LM, Huh TJ, Searl MM, Daffner KR, Sperling RA. IQ-based norms for highly intelligent adults. The Clinical Neuropsychologist. 20: 637-48. PMID 16980251 DOI: 10.1080/13854040500477498  0.96
2006 Chua EF, Schacter DL, Rand-Giovannetti E, Sperling RA. Understanding metamemory: neural correlates of the cognitive process and subjective level of confidence in recognition memory. Neuroimage. 29: 1150-60. PMID 16303318 DOI: 10.1016/j.neuroimage.2005.09.058  0.96
2006 Rand-Giovannetti E, Chua EF, Driscoll AE, Schacter DL, Albert MS, Sperling RA. Hippocampal and neocortical activation during repetitive encoding in older persons. Neurobiology of Aging. 27: 173-82. PMID 16298252 DOI: 10.1016/j.neurobiolaging.2004.12.013  0.96
2005 Dickerson BC, Salat DH, Greve DN, Chua EF, Rand-Giovannetti E, Rentz DM, Bertram L, Mullin K, Tanzi RE, Blacker D, Albert MS, Sperling RA. Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD. Neurology. 65: 404-11. PMID 16087905 DOI: 10.1212/01.wnl.0000171450.97464.49  0.96
2005 Dickerson BC, Sperling RA. Neuroimaging biomarkers for clinical trials of disease-modifying therapies in Alzheimer's disease. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 2: 348-60. PMID 15897955 DOI: 10.1602/neurorx.2.2.348  0.96
2004 Chua EF, Rand-Giovannetti E, Schacter DL, Albert MS, Sperling RA. Dissociating confidence and accuracy: functional magnetic resonance imaging shows origins of the subjective memory experience. Journal of Cognitive Neuroscience. 16: 1131-42. PMID 15453969 DOI: 10.1162/0898929041920568  0.96
2004 Dickerson BC, Salat DH, Bates JF, Atiya M, Killiany RJ, Greve DN, Dale AM, Stern CE, Blacker D, Albert MS, Sperling RA. Medial temporal lobe function and structure in mild cognitive impairment. Annals of Neurology. 56: 27-35. PMID 15236399 DOI: 10.1002/ana.20163  0.96
2004 Rentz DM, Huh TJ, Faust RR, Budson AE, Scinto LF, Sperling RA, Daffner KR. Use of IQ-adjusted norms to predict progressive cognitive decline in highly intelligent older individuals. Neuropsychology. 18: 38-49. PMID 14744186 DOI: 10.1037/0894-4105.18.1.38  0.96
2004 Lange N, Lake S, Sperling R, Brown J, Routledge C, Albert M, Heckers S. Two macroscopic and microscopic brain imaging studies of human hippocampus in early Alzheimer's disease and schizophrenia research. Statistics in Medicine. 23: 327-50. PMID 14716733 DOI: 10.1002/sim.1720  0.96
2003 Sperling R, Chua E, Cocchiarella A, Rand-Giovannetti E, Poldrack R, Schacter DL, Albert M. Putting names to faces: successful encoding of associative memories activates the anterior hippocampal formation. Neuroimage. 20: 1400-10. PMID 14568509 DOI: 10.1016/S1053-8119(03)00391-4  0.96
2003 Monsonego A, Zota V, Karni A, Krieger JI, Bar-Or A, Bitan G, Budson AE, Sperling R, Selkoe DJ, Weiner HL. Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease. The Journal of Clinical Investigation. 112: 415-22. PMID 12897209 DOI: 10.1172/JCI18104  0.96
2003 Sperling RA, Bates JF, Chua EF, Cocchiarella AJ, Rentz DM, Rosen BR, Schacter DL, Albert MS. fMRI studies of associative encoding in young and elderly controls and mild Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 74: 44-50. PMID 12486265 DOI: 10.1136/jnnp.74.1.44  0.96
2002 Budson AE, Michalska KJ, Rentz DM, Joubert CC, Daffner KR, Schacter DL, Sperling RA. Use of a false recognition paradigm in an Alzheimer's disease clinical trial: a pilot study. American Journal of Alzheimer's Disease and Other Dementias. 17: 93-100. PMID 11954675  0.96
2002 Sperling R, Greve D, Dale A, Killiany R, Holmes J, Rosas HD, Cocchiarella A, Firth P, Rosen B, Lake S, Lange N, Routledge C, Albert M. Functional MRI detection of pharmacologically induced memory impairment. Proceedings of the National Academy of Sciences of the United States of America. 99: 455-60. PMID 11756667 DOI: 10.1073/pnas.012467899  0.96
2001 Sperling RA, Bates JF, Cocchiarella AJ, Schacter DL, Rosen BR, Albert MS. Encoding novel face-name associations: a functional MRI study. Human Brain Mapping. 14: 129-39. PMID 11559958 DOI: 10.1002/hbm.1047  0.96
2001 Sperling R. The volumes of memory. Journal of Neurology, Neurosurgery, and Psychiatry. 71: 5. PMID 11413252 DOI: 10.1136/jnnp.71.1.5  0.96
2001 Johnson KA, Lopera F, Jones K, Becker A, Sperling R, Hilson J, Londono J, Siegert I, Arcos M, Moreno S, Madrigal L, Ossa J, Pineda N, Ardila A, Roselli M, et al. Presenilin-1-associated abnormalities in regional cerebral perfusion. Neurology. 56: 1545-51. PMID 11402113  0.96
2001 Sperling RA, Guttmann CR, Hohol MJ, Warfield SK, Jakab M, Parente M, Diamond EL, Daffner KR, Olek MJ, Orav EJ, Kikinis R, Jolesz FA, Weiner HL. Regional magnetic resonance imaging lesion burden and cognitive function in multiple sclerosis: a longitudinal study. Archives of Neurology. 58: 115-21. PMID 11176944  0.96
2000 Greenberg SM, Tennis MK, Brown LB, Gomez-Isla T, Hayden DL, Schoenfeld DA, Walsh KL, Corwin C, Daffner KR, Friedman P, Meadows ME, Sperling RA, Growdon JH. Donepezil therapy in clinical practice: a randomized crossover study. Archives of Neurology. 57: 94-9. PMID 10634454  0.96
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