Daniel D. Oprian, Ph.D. - Publications

Affiliations: 
Biochemistry Brandeis University, Waltham, MA, United States 
Area:
GPCR membrane protein crystallography

75/82 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Matos JO, Kumar RP, Ma AC, Patterson M, Krauss IJ, Oprian DD. Mechanism Underlying Anti-Markovnikov Addition in the Reaction of Pentalenene Synthase. Biochemistry. PMID 32786410 DOI: 10.1021/Acs.Biochem.0C00518  0.31
2019 Morehouse BR, Kumar RP, Matos JO, Yu Q, Bannister A, Malik K, Temme JS, Krauss IJ, Oprian DD. Direct evidence for an enzyme generated LPP intermediate in (+)-limonene synthase using a fluorinated GPP substrate analog. Acs Chemical Biology. PMID 31433159 DOI: 10.1021/Acschembio.9B00514  0.335
2019 Ozdeslik RN, Olinski LE, Trieu MM, Oprian DD, Oancea E. Human nonvisual opsin 3 regulates pigmentation of epidermal melanocytes through functional interaction with melanocortin 1 receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 31097585 DOI: 10.1073/Pnas.1902825116  0.414
2017 Kumar RP, Morehouse BR, Fofana J, Trieu MM, Zhou DH, Lorenz MO, Oprian DD. Structure and monomer/dimer equilibrium for the guanylyl cyclase domain of the optogenetics protein RhoGC. The Journal of Biological Chemistry. PMID 29118188 DOI: 10.1074/Jbc.M117.812685  0.465
2017 Lamarche LB, Kumar RP, Trieu MM, Devine EL, Theobald DL, Oprian DD. Purification and Characterization of RhoPDE, a Retinylidene/Phosphodiesterase Fusion Protein and Potential Optogenetics Tool from the Choanoflagellate Salpingoeca rosetta. Biochemistry. PMID 28976747 DOI: 10.1021/Acs.Biochem.7B00519  0.784
2017 Trieu MM, Devine EL, Lamarche LB, Ammerman AE, Greco JA, Birge RR, Theobald DL, Oprian DD. Expression, Purification, and Spectral Tuning of RhoGC, a Retinylidene/Guanylyl Cyclase Fusion Protein and Optogenetics Tool from the Aquatic Fungus Blastocladiella emersonii. The Journal of Biological Chemistry. PMID 28473465 DOI: 10.1074/Jbc.M117.789636  0.772
2017 Kumar RP, Morehouse BR, Matos JO, Malik K, Lin H, Krauss IJ, Oprian DD. Structural Characterization of Early Michaelis Complexes in the Reaction Catalyzed by (+)-Limonene Synthase from Citrus sinensis using Fluorinated Substrate Analogs. Biochemistry. PMID 28272876 DOI: 10.1021/Acs.Biochem.7B00144  0.342
2017 Morehouse BR, Kumar RP, Matos JO, Olsen SN, Entova S, Oprian DD. Functional and Structural Characterization of a (+)-Limonene Synthase from Citrus sinensis. Biochemistry. PMID 28272875 DOI: 10.1021/Acs.Biochem.7B00143  0.341
2016 Devine EL, Theobald DL, Oprian DD. Relocating the active-site lysine in rhodopsin: 2. Evolutionary intermediates. Biochemistry. PMID 27486845 DOI: 10.1021/Acs.Biochem.6B00478  0.8
2015 Chakrabarti KS, Agafonov RV, Pontiggia F, Otten R, Higgins MK, Schertler GF, Oprian DD, Kern D. Conformational Selection in a Protein-Protein Interaction Revealed by Dynamic Pathway Analysis. Cell Reports. PMID 26725117 DOI: 10.1016/J.Celrep.2015.12.010  0.399
2015 Kumar RP, Ranaghan MJ, Ganjei AY, Oprian DD. Crystal Structure of Recoverin with Calcium Ions Bound to Both Functional EF-Hands. Biochemistry. PMID 26584024 DOI: 10.1021/Acs.Biochem.5B01160  0.723
2014 D'Antona AM, Xie G, Sligar SG, Oprian DD. Assembly of an activated rhodopsin-transducin complex in nanoscale lipid bilayers. Biochemistry. 53: 127-34. PMID 24328127 DOI: 10.1021/Bi4012995  0.349
2014 Frederiksen R, Boyer NP, Nickle B, Chakrabarti KS, Koutalos Y, Crouch RK, Oprian D, Cornwall MC. Correction to Low aqueous solubility of 11-cis-retinal limits the rate of pigment formation and dark adaptation in salamander rods [The Journal of General Physiology, 139,6 (2012), 493-505] Journal of General Physiology. 144: 487. DOI: 10.1085/jgp.20111068510152014c  0.767
2013 Ranaghan MJ, Kumar RP, Chakrabarti KS, Buosi V, Kern D, Oprian DD. A highly conserved cysteine of neuronal calcium-sensing proteins controls cooperative binding of Ca2+ to recoverin. The Journal of Biological Chemistry. 288: 36160-7. PMID 24189072 DOI: 10.1074/Jbc.M113.524355  0.73
2013 Devine EL, Oprian DD, Theobald DL. Relocating the active-site lysine in rhodopsin and implications for evolution of retinylidene proteins. Proceedings of the National Academy of Sciences of the United States of America. 110: 13351-5. PMID 23904486 DOI: 10.1073/Pnas.1306826110  0.795
2012 Frederiksen R, Boyer NP, Nickle B, Chakrabarti KS, Koutalos Y, Crouch RK, Oprian D, Cornwall MC. Low aqueous solubility of 11-cis-retinal limits the rate of pigment formation and dark adaptation in salamander rods. The Journal of General Physiology. 139: 493-505. PMID 22641642 DOI: 10.1085/Jgp.201110685  0.768
2012 Deupi X, Edwards P, Singhal A, Nickle B, Oprian D, Schertler G, Standfuss J. Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II. Proceedings of the National Academy of Sciences of the United States of America. 109: 119-24. PMID 22198838 DOI: 10.1073/Pnas.1114089108  0.805
2011 Xie G, D'Antona AM, Edwards PC, Fransen M, Standfuss J, Schertler GF, Oprian DD. Preparation of an activated rhodopsin/transducin complex using a constitutively active mutant of rhodopsin. Biochemistry. 50: 10399-407. PMID 21995315 DOI: 10.1021/Bi201126R  0.415
2011 Standfuss J, Edwards PC, D'Antona A, Fransen M, Xie G, Oprian DD, Schertler GF. The structural basis of agonist-induced activation in constitutively active rhodopsin. Nature. 471: 656-60. PMID 21389983 DOI: 10.1038/Nature09795  0.49
2009 D'Antona A, Xie G, Fransen M, Edwards PC, Schertler GF, Oprian DD. Purification and Characterization of an Activated Rhodopsin/Transducin Complex Biophysical Journal. 96: 594a. DOI: 10.1016/J.Bpj.2008.12.3172  0.44
2007 Standfuss J, Xie G, Edwards PC, Burghammer M, Oprian DD, Schertler GF. Crystal structure of a thermally stable rhodopsin mutant. Journal of Molecular Biology. 372: 1179-88. PMID 17825322 DOI: 10.1016/J.Jmb.2007.03.007  0.426
2007 Bayburt TH, Leitz AJ, Xie G, Oprian DD, Sligar SG. Transducin activation by nanoscale lipid bilayers containing one and two rhodopsins. The Journal of Biological Chemistry. 282: 14875-81. PMID 17395586 DOI: 10.1074/Jbc.M701433200  0.384
2006 Chen J, Shi G, Concepcion FA, Xie G, Oprian D. Stable rhodopsin/arrestin complex leads to retinal degeneration in a transgenic mouse model of autosomal dominant retinitis pigmentosa Journal of Neuroscience. 26: 11929-11937. PMID 17108167 DOI: 10.1523/Jneurosci.3212-06.2006  0.395
2006 Higgins MK, Oprian DD, Schertler GF. Recoverin binds exclusively to an amphipathic peptide at the N terminus of rhodopsin kinase, inhibiting rhodopsin phosphorylation without affecting catalytic activity of the kinase. The Journal of Biological Chemistry. 281: 19426-32. PMID 16675451 DOI: 10.1074/Jbc.M602203200  0.358
2006 Tam BM, Xie G, Oprian DD, Moritz OL. Mislocalized rhodopsin does not require activation to cause retinal degeneration and neurite outgrowth in Xenopus laevis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 203-9. PMID 16399688 DOI: 10.1523/Jneurosci.3849-05.2006  0.47
2005 Kono M, Crouch RK, Oprian DD. A dark and constitutively active mutant of the tiger salamander UV pigment. Biochemistry. 44: 799-804. PMID 15641808 DOI: 10.1021/Bi047898F  0.521
2004 Kim JM, Altenbach C, Kono M, Oprian DD, Hubbell WL, Khorana HG. Structural origins of constitutive activation in rhodopsin: Role of the K296/E113 salt bridge. Proceedings of the National Academy of Sciences of the United States of America. 101: 12508-13. PMID 15306683 DOI: 10.1073/Pnas.0404519101  0.571
2004 Das J, Crouch RK, Ma JX, Oprian DD, Kono M. Role of the 9-methyl group of retinal in cone visual pigments. Biochemistry. 43: 5532-8. PMID 15122919 DOI: 10.1021/Bi036097U  0.422
2003 Jin S, Cornwall MC, Oprian DD. Opsin activation as a cause of congenital night blindness. Nature Neuroscience. 6: 731-5. PMID 12778053 DOI: 10.1038/Nn1070  0.53
2003 Jin S, McKee TD, Oprian DD. An improved rhodopsin/EGFP fusion protein for use in the generation of transgenic Xenopus laevis. Febs Letters. 542: 142-6. PMID 12729914 DOI: 10.1016/S0014-5793(03)00368-5  0.777
2003 Oprian DD. Phototaxis, chemotaxis and the missing link. Trends in Biochemical Sciences. 28: 167-9. PMID 12713898 DOI: 10.1016/S0968-0004(03)00056-2  0.373
2003 Gross AK, Rao VR, Oprian DD. Characterization of rhodopsin congenital night blindness mutant T94I. Biochemistry. 42: 2009-15. PMID 12590588 DOI: 10.1021/Bi020613J  0.751
2003 Gross AK, Xie G, Oprian DD. Slow binding of retinal to rhodopsin mutants G90D and T94D. Biochemistry. 42: 2002-8. PMID 12590587 DOI: 10.1021/Bi020612R  0.739
2003 Xie G, Gross AK, Oprian DD. An opsin mutant with increased thermal stability. Biochemistry. 42: 1995-2001. PMID 12590586 DOI: 10.1021/Bi020611Z  0.751
2002 Fasick JI, Applebury ML, Oprian DD. Spectral tuning in the mammalian short-wavelength sensitive cone pigments. Biochemistry. 41: 6860-5. PMID 12022891 DOI: 10.1021/Bi0200413  0.377
2002 Abdulaev NG, Strassmaier TT, Ngo T, Chen R, Luecke H, Oprian DD, Ridge KD. Grafting segments from the extracellular surface of CCR5 onto a bacteriorhodopsin transmembrane scaffold confers HIV-1 coreceptor activity. Structure (London, England : 1993). 10: 515-25. PMID 11937056 DOI: 10.1016/S0969-2126(02)00752-9  0.314
2001 Ma J, Znoiko S, Othersen KL, Ryan JC, Das J, Isayama T, Kono M, Oprian DD, Corson DW, Cornwall MC, Cameron DA, Harosi FI, Makino CL, Crouch RK. A visual pigment expressed in both rod and cone photoreceptors. Neuron. 32: 451-61. PMID 11709156 DOI: 10.1016/S0896-6273(01)00482-2  0.392
2001 Ma JX, Kono M, Xu L, Das J, Ryan JC, Hazard ES, Oprian DD, Crouch RK. Salamander UV cone pigment: sequence, expression, and spectral properties. Visual Neuroscience. 18: 393-9. PMID 11497415 DOI: 10.1017/S0952523801183057  0.364
2000 Struthers M, Yu H, Oprian DD. G protein-coupled receptor activation: analysis of a highly constrained, "straitjacketed" rhodopsin. Biochemistry. 39: 7938-42. PMID 10891074 DOI: 10.1021/Bi000771F  0.396
1999 Fasick JI, Lee N, Oprian DD. Spectral tuning in the human blue cone pigment. Biochemistry. 38: 11593-6. PMID 10512613 DOI: 10.1021/Bi991600H  0.432
1999 Yu H, Oprian DD. Tertiary interactions between transmembrane segments 3 and 5 near the cytoplasmic side of rhodopsin. Biochemistry. 38: 12033-40. PMID 10508407 DOI: 10.1021/Bi9909492  0.395
1999 Struthers M, Yu H, Kono M, Oprian DD. Tertiary interactions between the fifth and sixth transmembrane segments of rhodopsin. Biochemistry. 38: 6597-603. PMID 10350478 DOI: 10.1021/Bi9902384  0.417
1998 Kono M, Yu H, Oprian DD. Disulfide bond exchange in rhodopsin. Biochemistry. 37: 1302-5. PMID 9477956 DOI: 10.1021/Bi9721445  0.387
1997 Yang T, Snider BB, Oprian DD. Synthesis and characterization of a novel retinylamine analog inhibitor of constitutively active rhodopsin mutants found in patients with autosomal dominant retinitis pigmentosa. Proceedings of the National Academy of Sciences of the United States of America. 94: 13559-64. PMID 9391065 DOI: 10.1073/Pnas.94.25.13559  0.486
1997 Rim J, Faurobert E, Hurley JB, Oprian DD. In vitro assay for trans-phosphorylation of rhodopsin by rhodopsin kinase. Biochemistry. 36: 7064-70. PMID 9188705 DOI: 10.1021/Bi970470E  0.372
1997 Kochendoerfer GG, Wang Z, Oprian DD, Mathies RA. Resonance Raman examination of the wavelength regulation mechanism in human visual pigments. Biochemistry. 36: 6577-87. PMID 9184137 DOI: 10.1021/Bi970322O  0.362
1996 Rao VR, Oprian DD. Activating mutations of rhodopsin and other G protein-coupled receptors. Annual Review of Biophysics and Biomolecular Structure. 25: 287-314. PMID 8800472 DOI: 10.1146/Annurev.Bb.25.060196.001443  0.483
1995 Yu H, Kono M, McKee TD, Oprian DD. A general method for mapping tertiary contacts between amino acid residues in membrane-embedded proteins. Biochemistry. 34: 14963-9. PMID 7578109 DOI: 10.1021/Bi00046A002  0.756
1995 Rim J, Oprian DD. Constitutive activation of opsin: interaction of mutants with rhodopsin kinase and arrestin. Biochemistry. 34: 11938-45. PMID 7547930 DOI: 10.1021/Bi00037A035  0.462
1994 Asenjo AB, Rim J, Oprian DD. Molecular determinants of human red/green color discrimination. Neuron. 12: 1131-8. PMID 8185948 DOI: 10.1016/0896-6273(94)90320-4  0.386
1994 Govardhan CP, Oprian DD. Active site-directed inactivation of constitutively active mutants of rhodopsin. The Journal of Biological Chemistry. 269: 6524-7. PMID 8120004  0.388
1994 Rao VR, Cohen GB, Oprian DD. Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness. Nature. 367: 639-42. PMID 8107847 DOI: 10.1038/367639A0  0.471
1993 Wang Z, Asenjo AB, Oprian DD. Identification of the Cl(-)-binding site in the human red and green color vision pigments. Biochemistry. 32: 2125-30. PMID 8443153 DOI: 10.1021/Bi00060A001  0.39
1993 Dryja TP, Berson EL, Rao VR, Oprian DD. Heterozygous missense mutation in the rhodopsin gene as a cause of congenital stationary night blindness. Nature Genetics. 4: 280-3. PMID 8358437 DOI: 10.1038/Ng0793-280  0.42
1993 Cohen GB, Yang T, Robinson PR, Oprian DD. Constitutive activation of opsin: influence of charge at position 134 and size at position 296. Biochemistry. 32: 6111-5. PMID 8099498 DOI: 10.1021/Bi00074A024  0.638
1992 Oprian DD. Molecular determinants of spectral properties and signal transduction in the visual pigments. Current Opinion in Neurobiology. 2: 428-32. PMID 1525538 DOI: 10.1016/0959-4388(92)90175-K  0.415
1992 Cohen GB, Oprian DD, Robinson PR. Mechanism of activation and inactivation of opsin: role of Glu113 and Lys296. Biochemistry. 31: 12592-601. PMID 1472495 DOI: 10.1021/Bi00165A008  0.642
1992 Robinson PR, Cohen GB, Zhukovsky EA, Oprian DD. Constitutively active mutants of rhodopsin. Neuron. 9: 719-25. PMID 1356370 DOI: 10.1016/0896-6273(92)90034-B  0.654
1992 Zhukovsky EA, Robinson PR, Oprian DD. Changing the location of the Schiff base counterion in rhodopsin. Biochemistry. 31: 10400-5. PMID 1329948 DOI: 10.1021/Bi00157A030  0.603
1992 Oprian DD. The ligand-binding domain of rhodopsin and other G protein-linked receptors. Journal of Bioenergetics and Biomembranes. 24: 211-7. PMID 1326517 DOI: 10.1007/Bf00762679  0.406
1991 Zhukovsky EA, Robinson PR, Oprian DD. Transducin activation by rhodopsin without a covalent bond to the 11-cis-retinal chromophore. Science (New York, N.Y.). 251: 558-60. PMID 1990431 DOI: 10.1126/Science.1990431  0.67
1991 Oprian DD, Asenjo AB, Lee N, Pelletier SL. Design, chemical synthesis, and expression of genes for the three human color vision pigments. Biochemistry. 30: 11367-72. PMID 1742276 DOI: 10.1021/Bi00112A002  0.367
1989 Zhukovsky EA, Oprian DD. Effect of carboxylic acid side chains on the absorption maximum of visual pigments. Science (New York, N.Y.). 246: 928-30. PMID 2573154 DOI: 10.1126/Science.2573154  0.398
1988 Franke RR, Sakmar TP, Oprian DD, Khorana HG. A single amino acid substitution in rhodopsin (lysine 248----leucine) prevents activation of transducin. The Journal of Biological Chemistry. 263: 2119-22. PMID 3123487  0.672
1987 Oprian DD, Molday RS, Kaufman RJ, Khorana HG. Expression of a synthetic bovine rhodopsin gene in monkey kidney cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 8874-8. PMID 2962193 DOI: 10.1073/Pnas.84.24.8874  0.557
1986 Ferretti L, Karnik SS, Khorana HG, Nassal M, Oprian DD. Total synthesis of a gene for bovine rhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 83: 599-603. PMID 3456156 DOI: 10.1073/Pnas.83.3.599  0.479
1985 Yatsunami K, Pandya BV, Oprian DD, Khorana HG. cDNA-derived amino acid sequence of the gamma subunit of GTPase from bovine rod outer segments. Proceedings of the National Academy of Sciences of the United States of America. 82: 1936-40. PMID 2984674 DOI: 10.1073/Pnas.82.7.1936  0.478
1985 Barrett DJ, Redmond TM, Wiggert B, Oprian DD, Chader GJ, Nickerson JM. cDNA clones encoding bovine interphotoreceptor retinoid binding protein. Biochemical and Biophysical Research Communications. 131: 1086-93. PMID 2413855 DOI: 10.1016/0006-291X(85)90202-5  0.339
1983 Oprian DD, Gorsky LD, Coon MJ. Properties of the oxygenated form of liver microsomal cytochrome P-450. The Journal of Biological Chemistry. 258: 8684-91. PMID 6863307  0.475
1982 Oprian DD, Coon MJ. Oxidation-reduction states of FMN and FAD in NADPH-cytochrome P-450 reductase during reduction by NADPH. The Journal of Biological Chemistry. 257: 8935-44. PMID 6807985  0.46
1980 Oprian DD, Vatsis KP, Coon MJ. Kinetic Study Of Cytochrome P-450 Lm4 Reduction In A Reconstituted Liver Microsomal Enzyme System Microsomes, Drug Oxidations and Chemical Carcinogenesis. 383-386. DOI: 10.1016/B978-0-12-187701-9.50076-0  0.516
1980 White RE, Oprian DD, Coon MJ. Resolution Of Multiple Equilibria In Binding Of Small Molecules To Cytochrome P-450 Lm Microsomes, Drug Oxidations and Chemical Carcinogenesis. 243-251. DOI: 10.1016/B978-0-12-187701-9.50049-8  0.56
1979 Oprian DD, Vatsis KP, Coon MJ. Kinetics of reduction of cytochrome P-450LM4 in a reconstituted liver microsomal enzyme system. The Journal of Biological Chemistry. 254: 8895-902. PMID 113404  0.434
1979 Vatsis KP, Oprian DD, Coon MJ. Kinetics of reduction of purified liver microsomal cytochrome P-450 in the reconstituted enzyme system studied by stopped flow spectrophotometry. Acta Biologica Et Medica Germanica. 38: 459-73. PMID 42251  0.451
1979 Coon MJ, Blake RC, Oprian DD, Ballou DP. Mechanistic studies with purified components of the liver microsomal hydroxylation system: spectral intermediates in reaction of cytochrome P-450 with peroxy compounds. Acta Biologica Et Medica Germanica. 38: 449-58. PMID 42250  0.615
Low-probability matches (unlikely to be authored by this person)
1999 Yu H, Kono M, Oprian DD. State-dependent disulfide cross-linking in rhodopsin. Biochemistry. 38: 12028-32. PMID 10508406 DOI: 10.1021/Bi990948+  0.299
2000 Struthers M, Oprian DD. Mapping tertiary contacts between amino acid residues within rhodopsin. Methods in Enzymology. 315: 130-43. PMID 10736699 DOI: 10.1016/S0076-6879(00)15840-9  0.267
2023 Schiff WH, Oprian DD. Mutational Analysis of (+)-Limonene Synthase. Biochemistry. 62: 2472-2479. PMID 37531404 DOI: 10.1021/acs.biochem.3c00217  0.21
1984 Yatsunami K, Pandya BV, Oprian DD, Khorana G. The cloning of the genes for the GTPase and cyclic GMP phosphodiesterase of rod outer segments Federation Proceedings. 43: no. 1800.  0.151
1999 Ferrer M, Kapoor TM, Strassmaier T, Weissenhorn W, Skehel JJ, Oprian D, Schreiber SL, Wiley DC, Harrison SC. Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements. Nature Structural Biology. 6: 953-60. PMID 10504731 DOI: 10.1038/13324  0.133
2000 Zhou G, Ferrer M, Chopra R, Kapoor TM, Strassmaier T, Weissenhorn W, Skehel JJ, Oprian D, Schreiber SL, Harrison SC, Wiley DC. The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core. Bioorganic & Medicinal Chemistry. 8: 2219-27. PMID 11026535 DOI: 10.1016/S0968-0896(00)00155-3  0.118
1995 Oprian DD. Structure of the cGMP-gated channel Behavioral and Brain Sciences. 18: 482-483.  0.041
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