| Year |
Citation |
Score |
| 2016 |
Poirier S, Hamouda HA, Villeneuve L, Demers A, Mayer G. Trafficking Dynamics of PCSK9-Induced LDLR Degradation: Focus on Human PCSK9 Mutations and C-Terminal Domain. Plos One. 11: e0157230. PMID 27280970 DOI: 10.1371/Journal.Pone.0157230 |
0.496 |
|
| 2015 |
Poirier S, Mamarbachi M, Chen WT, Lee AS, Mayer G. GRP94 Regulates Circulating Cholesterol Levels through Blockade of PCSK9-Induced LDLR Degradation. Cell Reports. PMID 26628375 DOI: 10.1016/J.Atherosclerosis.2015.04.072 |
0.504 |
|
| 2015 |
Butkinaree C, Canuel M, Essalmani R, Poirier S, Benjannet S, Asselin MC, Roubtsova A, Hamelin J, Marcinkiewicz J, Chamberland A, Guillemot J, Mayer G, Sisodia SS, Jacob Y, Prat A, et al. Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other. The Journal of Biological Chemistry. 290: 18609-20. PMID 26085104 DOI: 10.1074/Jbc.M115.647180 |
0.603 |
|
| 2014 |
Poirier S, Samami S, Mamarbachi M, Demers A, Chang TY, Vance DE, Hatch GM, Mayer G. The epigenetic drug 5-azacytidine interferes with cholesterol and lipid metabolism. The Journal of Biological Chemistry. 289: 18736-51. PMID 24855646 DOI: 10.1074/Jbc.M114.563650 |
0.407 |
|
| 2013 |
Poirier S, Mayer G. The biology of PCSK9 from the endoplasmic reticulum to lysosomes: new and emerging therapeutics to control low-density lipoprotein cholesterol. Drug Design, Development and Therapy. 7: 1135-48. PMID 24115837 DOI: 10.2147/Dddt.S36984 |
0.486 |
|
| 2013 |
Poirier S, Mayer G, Murphy SR, Garver WS, Chang TY, Schu P, Seidah NG. The cytosolic adaptor AP-1A is essential for the trafficking and function of Niemann-Pick type C proteins. Traffic (Copenhagen, Denmark). 14: 458-69. PMID 23350547 DOI: 10.1111/Tra.12046 |
0.532 |
|
| 2012 |
Seidah NG, Poirier S, Denis M, Parker R, Miao B, Mapelli C, Prat A, Wassef H, Davignon J, Hajjar KA, Mayer G. Annexin A2 is a natural extrahepatic inhibitor of the PCSK9-induced LDL receptor degradation. Plos One. 7: e41865. PMID 22848640 DOI: 10.1371/Journal.Pone.0041865 |
0.605 |
|
| 2012 |
Denis M, Marcinkiewicz J, Zaid A, Gauthier D, Poirier S, Lazure C, Seidah NG, Prat A. Gene inactivation of proprotein convertase subtilisin/kexin type 9 reduces atherosclerosis in mice. Circulation. 125: 894-901. PMID 22261195 DOI: 10.1161/Circulationaha.111.057406 |
0.589 |
|
| 2012 |
Seidah NG, Poirier S, Denis M, Parker R, Miao B, Mapelli C, Prat A, Wassef H, Davignon J, Hajjar KA, Mayer G. Adenoviral overexpression of AnxA2 in mouse liver significantly increases LDLR levels. Plos One. DOI: 10.1371/Journal.Pone.0041865.G005 |
0.444 |
|
| 2009 |
Poirier S, Mayer G, Poupon V, McPherson PS, Desjardins R, Ly K, Asselin MC, Day R, Duclos FJ, Witmer M, Parker R, Prat A, Seidah NG. Dissection of the endogenous cellular pathways of PCSK9-induced low density lipoprotein receptor degradation: evidence for an intracellular route. The Journal of Biological Chemistry. 284: 28856-64. PMID 19635789 DOI: 10.1074/Jbc.M109.037085 |
0.591 |
|
| 2008 |
Mayer G, Poirier S, Seidah NG. Annexin A2 is a C-terminal PCSK9-binding protein that regulates endogenous low density lipoprotein receptor levels. The Journal of Biological Chemistry. 283: 31791-801. PMID 18799458 DOI: 10.1074/Jbc.M805971200 |
0.568 |
|
| 2008 |
Seidah NG, Mayer G, Zaid A, Rousselet E, Nassoury N, Poirier S, Essalmani R, Prat A. The activation and physiological functions of the proprotein convertases. The International Journal of Biochemistry & Cell Biology. 40: 1111-25. PMID 18343183 DOI: 10.1016/J.Biocel.2008.01.030 |
0.551 |
|
| 2008 |
Poirier S, Mayer G, Benjannet S, Bergeron E, Marcinkiewicz J, Nassoury N, Mayer H, Nimpf J, Prat A, Seidah NG. The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2. The Journal of Biological Chemistry. 283: 2363-72. PMID 18039658 DOI: 10.1074/Jbc.M708098200 |
0.596 |
|
| 2006 |
Poirier S, Prat A, Marcinkiewicz E, Paquin J, Chitramuthu BP, Baranowski D, Cadieux B, Bennett HPJ, Seidah NG. Implication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous system Journal of Neurochemistry. 98: 838-850. PMID 16893422 DOI: 10.1111/J.1471-4159.2006.03928.X |
0.516 |
|
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