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Vijay M. Shahani, Ph.D. - Publications

Affiliations: 
2013 Chemistry University of Toronto, Toronto, ON, Canada 
Area:
Molecular Chemistry, Cell Biology, Oncology
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13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Shahani VM, Yue P, Haftchenary S, Zhao W, Lukkarila JL, Zhang X, Ball D, Nona C, Gunning PT, Turkson J. Retraction of "Identification of Purine-Scaffold Small-Molecule Inhibitors of Stat3 Activation by QSAR Studies". Acs Medicinal Chemistry Letters. 14: 1482. PMID 37849532 DOI: 10.1021/acsmedchemlett.3c00405  0.62
2014 Martic S, Rains MK, Haftchenary S, Shahani VM, Kraskouskaya D, Ball DP, Gunning PT, Kraatz HB. Electrochemical detection of the Fc-STAT3 phosphorylation and STAT3-Fc-STAT3 dimerization and inhibition. Molecular Biosystems. 10: 576-80. PMID 24402062 DOI: 10.1039/C3Mb70493A  0.693
2013 Haftchenary S, Luchman HA, Jouk AO, Veloso AJ, Page BD, Cheng XR, Dawson SS, Grinshtein N, Shahani VM, Kerman K, Kaplan DR, Griffin C, Aman AM, Al-Awar R, Weiss S, et al. Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma. Acs Medicinal Chemistry Letters. 4: 1102-7. PMID 24900612 DOI: 10.1021/ml4003138  0.721
2013 Shahani VM, Ball DP, Ramos AV, Li Z, Spagnuolo PA, Haftchenary S, Schimmer AD, Trudel S, Gunning PT. A 2,6,9-hetero-trisubstituted purine inhibitor exhibits potent biological effects against multiple myeloma cells. Bioorganic & Medicinal Chemistry. 21: 5618-28. PMID 23810672 DOI: 10.1016/J.Bmc.2013.04.080  0.646
2013 Haftchenary S, Ball DP, Aubry I, Landry M, Shahani VM, Fletcher S, Page BDG, Jouk AO, Tremblay ML, Gunning PT. Identification of a potent salicylic acid-based inhibitor of tyrosine phosphatase PTP1B Medchemcomm. 4: 987-992. DOI: 10.1039/C3Md00011G  0.626
2011 Lukkarila JL, da Silva SR, Ali M, Shahani VM, Xu GW, Berman J, Roughton A, Dhe-Paganon S, Schimmer AD, Gunning PT. Identification of NAE Inhibitors Exhibiting Potent Activity in Leukemia Cells: Exploring the Structural Determinants of NAE Specificity. Acs Medicinal Chemistry Letters. 2: 577-82. PMID 24900352 DOI: 10.1021/Ml2000615  0.619
2011 Shahani VM, Yue P, Haftchenary S, Zhao W, Lukkarila JL, Zhang X, Ball D, Nona C, Gunning PT, Turkson J. Identification of Purine-Scaffold Small-Molecule Inhibitors of Stat3 Activation by QSAR Studies. Acs Medicinal Chemistry Letters. 2: 79-84. PMID 21243039 DOI: 10.1021/Ml100224D  0.713
2011 Shahani VM, Yue P, Fletcher S, Sharmeen S, Sukhai MA, Luu DP, Zhang X, Sun H, Zhao W, Schimmer AD, Turkson J, Gunning PT. Design, synthesis, and in vitro characterization of novel hybrid peptidomimetic inhibitors of STAT3 protein. Bioorganic & Medicinal Chemistry. 19: 1823-38. PMID 21216604 DOI: 10.1016/J.Bmc.2010.12.010  0.726
2010 Fletcher S, Shahani VM, Lough AJ, Gunning PT. Concise access to N9-mono-, N2-mono- and N2,N9-di-substituted guanines via efficient Mitsunobu reactions Tetrahedron. 66: 4621-4632. DOI: 10.1016/J.Tet.2010.03.118  0.524
2009 Fletcher S, Drewry JA, Shahani VM, Page BD, Gunning PT. Molecular disruption of oncogenic signal transducer and activator of transcription 3 (STAT3) protein. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 87: 825-33. PMID 19935868 DOI: 10.1139/o09-044  0.629
2009 Fletcher S, Singh J, Zhang X, Yue P, Page BD, Sharmeen S, Shahani VM, Zhao W, Schimmer AD, Turkson J, Gunning PT. Disruption of transcriptionally active Stat3 dimers with non-phosphorylated, salicylic acid-based small molecules: potent in vitro and tumor cell activities. Chembiochem : a European Journal of Chemical Biology. 10: 1959-64. PMID 19644994 DOI: 10.1002/Cbic.200900172  0.751
2009 Fletcher S, Shahani VM, Gunning PT. Facile and efficient access to 2,6,9-tri-substituted purines through sequential N9, N2 Mitsunobu reactions Tetrahedron Letters. 50: 4258-4261. DOI: 10.1016/J.Tetlet.2009.04.137  0.509
2009 Fletcher S, Singh J, Zhang X, Yue P, Page BDG, Sharmeen S, Shahani VM, Zhao W, Schimmer AD, Turkson J, Gunning PT. Inside Cover: Disruption of Transcriptionally Active Stat3 Dimers with Non-phosphorylated, Salicylic Acid-Based Small Molecules: Potent in vitro and Tumor Cell Activities (ChemBioChem 12/2009) Chembiochem. 10: 1906-1906. DOI: 10.1002/Cbic.200990048  0.656
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