Dennis R. Grayson, Ph.D. - Publications

Affiliations: 
Psychiatry University of Illinois at Chicago, Chicago, IL, United States 
Area:
epigenetics

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Gatta E, Grayson DR, Auta J, Saudagar V, Dong E, Chen Y, Krishnan HR, Drnevich J, Pandey SC, Guidotti A. Genome-wide methylation in alcohol use disorder subjects: implications for an epigenetic regulation of the cortico-limbic glucocorticoid receptors (NR3C1). Molecular Psychiatry. PMID 31239533 DOI: 10.1038/S41380-019-0449-6  0.413
2019 Sakharkar AJ, Kyzar EJ, Gavin DP, Zhang H, Chen Y, Krishnan HR, Grayson DR, Pandey SC. Altered amygdala DNA methylation mechanisms after adolescent alcohol exposure contributes to adult anxiety and alcohol drinking. Neuropharmacology. 107679. PMID 31229451 DOI: 10.1016/J.Neuropharm.2019.107679  0.356
2018 Dong E, Locci V, Gatta E, Grayson DR, Guidotti A. N-Phthalyl-L-tryptophan (RG108), like clozapine (CLO), induces chromatin remodeling in brains of prenatally stressed mice. Molecular Pharmacology. PMID 30397000 DOI: 10.1124/Mol.118.113415  0.419
2018 Grayson DR, Guidotti A. DNA Methylation in Animal Models of Psychosis. Progress in Molecular Biology and Translational Science. 157: 105-132. PMID 29933947 DOI: 10.1016/Bs.Pmbts.2017.12.012  0.425
2017 Gatta E, Auta J, Gavin DP, Bhaumik DK, Grayson DR, Pandey SC, Guidotti A. Emerging role of one-carbon metabolism and DNA methylation enrichment on δ-containing GABAA receptor expression in the cerebellum of subjects with alcohol use disorders (AUD). The International Journal of Neuropsychopharmacology. PMID 29020412 DOI: 10.1093/Ijnp/Pyx075  0.369
2017 Gavin DP, Grayson DR, Varghese SP, Guizzetti M. Chromatin Switches during Neural Cell Differentiation and Their Dysregulation by Prenatal Alcohol Exposure. Genes. 8. PMID 28492482 DOI: 10.3390/Genes8050137  0.331
2017 Zhubi A, Chen Y, Guidotti A, Grayson DR. Epigenetic regulation of RELN and GAD1 in the frontal cortex (FC) of autism spectrum disorder (ASD) subjects. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. PMID 28229923 DOI: 10.1016/J.Ijdevneu.2017.02.003  0.471
2016 Guidotti A, Grayson DR, Caruncho HJ. Epigenetic RELN Dysfunction in Schizophrenia and Related Neuropsychiatric Disorders. Frontiers in Cellular Neuroscience. 10: 89. PMID 27092053 DOI: 10.3389/Fncel.2016.00089  0.707
2016 Millan MJ, Andrieux A, Bartzokis G, Cadenhead K, Dazzan P, Fusar-Poli P, Gallinat J, Giedd J, Grayson DR, Heinrichs M, Kahn R, Krebs MO, Leboyer M, Lewis D, Marin O, et al. Altering the course of schizophrenia: progress and perspectives. Nature Reviews. Drug Discovery. PMID 26939910 DOI: 10.1038/Nrd.2016.28  0.355
2016 Dong E, Tueting P, Matrisciano F, Grayson DR, Guidotti A. Behavioral and molecular neuroepigenetic alterations in prenatally stressed mice: relevance for the study of chromatin remodeling properties of antipsychotic drugs. Translational Psychiatry. 6: e711. PMID 26756904 DOI: 10.1038/Tp.2015.191  0.436
2015 Labouesse MA, Dong E, Grayson D, Guidotti A, Meyer U. Maternal immune activation induces GAD1 and GAD2 promoter remodeling in the offspring prefrontal cortex. Epigenetics. 0. PMID 26575259 DOI: 10.1080/15592294.2015.1114202  0.422
2015 Grayson DR, Guidotti A. Merging data from genetic and epigenetic approaches to better understand autistic spectrum disorder. Epigenomics. PMID 26551091 DOI: 10.2217/Epi.15.92  0.373
2015 Dong E, Dzitoyeva SG, Matrisciano F, Tueting P, Grayson DR, Guidotti A. Brain-derived neurotrophic factor epigenetic modifications associated with schizophrenia-like phenotype induced by prenatal stress in mice. Biological Psychiatry. 77: 589-96. PMID 25444166 DOI: 10.1016/J.Biopsych.2014.08.012  0.381
2014 Dong E, Ruzicka WB, Grayson DR, Guidotti A. DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients. Schizophrenia Research. PMID 25476119 DOI: 10.1016/J.Schres.2014.10.030  0.493
2014 Guidotti A, Dong E, Tueting P, Grayson DR. Modeling the molecular epigenetic profile of psychosis in prenatally stressed mice. Progress in Molecular Biology and Translational Science. 128: 89-101. PMID 25410542 DOI: 10.1016/B978-0-12-800977-2.00004-8  0.406
2014 Guidotti A, Grayson DR. DNA methylation and demethylation as targets for antipsychotic therapy. Dialogues in Clinical Neuroscience. 16: 419-29. PMID 25364290  0.408
2014 Zhubi A, Cook EH, Guidotti A, Grayson DR. Epigenetic mechanisms in autism spectrum disorder. International Review of Neurobiology. 115: 203-44. PMID 25131546 DOI: 10.1016/B978-0-12-801311-3.00006-8  0.383
2014 Guidotti A, Auta J, Davis JM, Dong E, Gavin DP, Grayson DR, Sharma RP, Smith RC, Tueting P, Zhubi A. Toward the identification of peripheral epigenetic biomarkers of schizophrenia. Journal of Neurogenetics. 28: 41-52. PMID 24702539 DOI: 10.3109/01677063.2014.892485  0.446
2014 Zhubi A, Chen Y, Dong E, Cook EH, Guidotti A, Grayson DR. Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum. Translational Psychiatry. 4: e349. PMID 24448211 DOI: 10.1038/Tp.2013.123  0.432
2013 Guidotti A, Dong E, Gavin DP, Veldic M, Zhao W, Bhaumik DK, Pandey SC, Grayson DR. DNA methylation/demethylation network expression in psychotic patients with a history of alcohol abuse. Alcoholism, Clinical and Experimental Research. 37: 417-24. PMID 22958170 DOI: 10.1111/J.1530-0277.2012.01947.X  0.377
2013 Grayson DR, Guidotti A. The dynamics of DNA methylation in schizophrenia and related psychiatric disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 138-66. PMID 22948975 DOI: 10.1038/Npp.2012.125  0.506
2013 Matrisciano F, Tueting P, Dalal I, Kadriu B, Grayson DR, Davis JM, Nicoletti F, Guidotti A. Epigenetic modifications of GABAergic interneurons are associated with the schizophrenia-like phenotype induced by prenatal stress in mice. Neuropharmacology. 68: 184-94. PMID 22564440 DOI: 10.1016/J.Neuropharm.2012.04.013  0.442
2012 Kadriu B, Guidotti A, Chen Y, Grayson DR. DNA methyltransferases1 (DNMT1) and 3a (DNMT3a) colocalize with GAD67-positive neurons in the GAD67-GFP mouse brain. The Journal of Comparative Neurology. 520: 1951-64. PMID 22134929 DOI: 10.1002/Cne.23020  0.436
2012 Guidoni A, Dong E, Gavin DP, Grayson DR. Poster #115 INCREASED EXPRESSION OF PUTATIVE DNA DEMETHYLATION GENES IN PSYCHOSIS Schizophrenia Research. 136: S227. DOI: 10.1016/S0920-9964(12)70687-4  0.367
2011 Grayson DR. Laboratory of molecular neurobiology (1988-1994). Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 64: 339-43. PMID 21708255 DOI: 10.1016/J.Phrs.2011.05.021  0.372
2011 Redmond LC, Dumur CI, Archer KJ, Grayson DR, Haar JL, Lloyd JA. Krüppel-like factor 2 regulated gene expression in mouse embryonic yolk sac erythroid cells. Blood Cells, Molecules & Diseases. 47: 1-11. PMID 21530336 DOI: 10.1016/J.Bcmd.2011.03.002  0.351
2011 Guidotti A, Auta J, Chen Y, Davis JM, Dong E, Gavin DP, Grayson DR, Matrisciano F, Pinna G, Satta R, Sharma RP, Tremolizzo L, Tueting P. Epigenetic GABAergic targets in schizophrenia and bipolar disorder. Neuropharmacology. 60: 1007-16. PMID 21074545 DOI: 10.1016/J.Neuropharm.2010.10.021  0.514
2011 Chen Y, Dong E, Grayson DR. Analysis of the GAD1 promoter: trans-acting factors and DNA methylation converge on the 5' untranslated region. Neuropharmacology. 60: 1075-87. PMID 20869372 DOI: 10.1016/J.Neuropharm.2010.09.017  0.479
2011 Grayson DR, Kundakovic M, Chen Y, Dong E, Guidotti A. Epigenetic regulation of GABAergic targets in psychiatry Epigenetics and Human Health. 23-40. DOI: 10.1007/978-3-642-17426-1_2  0.686
2010 Grayson DR. Schizophrenia and the epigenetic hypothesis. Epigenomics. 2: 341-4. PMID 22121893 DOI: 10.2217/Epi.10.22  0.413
2010 Dong E, Chen Y, Gavin DP, Grayson DR, Guidotti A. Valproate induces DNA demethylation in nuclear extracts from adult mouse brain. Epigenetics : Official Journal of the Dna Methylation Society. 5: 730-5. PMID 20716949 DOI: 10.4161/Epi.5.8.13053  0.474
2010 Sharma RP, Gavin DP, Grayson DR. CpG methylation in neurons: message, memory, or mask? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2009-20. PMID 20631690 DOI: 10.1038/Npp.2010.85  0.452
2010 Grayson DR, Kundakovic M, Sharma RP. Is there a future for histone deacetylase inhibitors in the pharmacotherapy of psychiatric disorders? Molecular Pharmacology. 77: 126-35. PMID 19917878 DOI: 10.1124/Mol.109.061333  0.753
2009 Dong E, Grayson DR, Guidotti A, Costa E. Antipsychotic subtypes can be characterized by differences in their ability to modify GABAergic promoter methylation. Epigenomics. 1: 201-11. PMID 22122643 DOI: 10.2217/Epi.09.2  0.673
2009 Gavin DP, Rosen C, Chase K, Grayson DR, Tun N, Sharma RP. Dimethylated lysine 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures. Journal of Psychiatry & Neuroscience : Jpn. 34: 232-7. PMID 19448855  0.317
2009 Grayson DR, Chen Y, Dong E, Kundakovic M, Guidotti A. From trans-methylation to cytosine methylation: evolution of the methylation hypothesis of schizophrenia. Epigenetics : Official Journal of the Dna Methylation Society. 4: 144-9. PMID 19395859 DOI: 10.4161/Epi.4.3.8534  0.758
2009 Guidotti A, Dong E, Kundakovic M, Satta R, Grayson DR, Costa E. Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling. Trends in Pharmacological Sciences. 30: 55-60. PMID 19110320 DOI: 10.1016/J.Tips.2008.10.010  0.797
2009 Costa E, Chen Y, Dong E, Grayson DR, Kundakovic M, Maloku E, Ruzicka W, Satta R, Veldic M, Zhubi A, Guidotti A. GABAergic promoter hypermethylation as a model to study the neurochemistry of schizophrenia vulnerability. Expert Review of Neurotherapeutics. 9: 87-98. PMID 19102671 DOI: 10.1586/14737175.9.1.87  0.786
2009 Kundakovic M, Chen Y, Guidotti A, Grayson DR. The reelin and GAD67 promoters are activated by epigenetic drugs that facilitate the disruption of local repressor complexes. Molecular Pharmacology. 75: 342-54. PMID 19029285 DOI: 10.1124/Mol.108.051763  0.757
2008 Dong E, Nelson M, Grayson DR, Costa E, Guidotti A. Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation. Proceedings of the National Academy of Sciences of the United States of America. 105: 13614-9. PMID 18757738 DOI: 10.1073/Pnas.0805493105  0.577
2008 Gavin DP, Kartan S, Chase K, Grayson DR, Sharma RP. Reduced baseline acetylated histone 3 levels, and a blunted response to HDAC inhibition in lymphocyte cultures from schizophrenia subjects. Schizophrenia Research. 103: 330-2. PMID 18539439 DOI: 10.1016/J.Schres.2008.04.026  0.45
2008 Sharma RP, Tun N, Grayson DR. Depolarization induces downregulation of DNMT1 and DNMT3a in primary cortical cultures. Epigenetics : Official Journal of the Dna Methylation Society. 3: 74-80. PMID 18536530 DOI: 10.4161/Epi.3.2.6103  0.438
2008 Kharlamov EA, Downey KL, Jukkola PI, Grayson DR, Kelly KM. Expression of GABA A receptor alpha1 subunit mRNA and protein in rat neocortex following photothrombotic infarction. Brain Research. 1210: 29-38. PMID 18407248 DOI: 10.1016/J.Brainres.2008.02.070  0.357
2008 Sharma RP, Grayson DR, Gavin DP. Histone deactylase 1 expression is increased in the prefrontal cortex of schizophrenia subjects: analysis of the National Brain Databank microarray collection. Schizophrenia Research. 98: 111-7. PMID 17961987 DOI: 10.1016/J.Schres.2007.09.020  0.474
2008 Costa E, Chen Y, Dong E, Grayson DR, Guidotti A, Veldic M. Reelin downregulation as a prospective treatment target for GABAergic dysfunction in schizophrenia Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease. 341-363. DOI: 10.1007/978-0-387-76761-1_23  0.489
2007 Costa E, Dong E, Grayson DR, Guidotti A, Ruzicka W, Veldic M. Reviewing the role of DNA (cytosine-5) methyltransferase overexpression in the cortical GABAergic dysfunction associated with psychosis vulnerability. Epigenetics : Official Journal of the Dna Methylation Society. 2: 29-36. PMID 17965595 DOI: 10.4161/Epi.2.1.4063  0.666
2007 Chen Y, Kundakovic M, Agis-Balboa RC, Pinna G, Grayson DR. Induction of the reelin promoter by retinoic acid is mediated by Sp1. Journal of Neurochemistry. 103: 650-65. PMID 17666047 DOI: 10.1111/J.1471-4159.2007.04797.X  0.697
2007 Dong E, Guidotti A, Grayson DR, Costa E. Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters. Proceedings of the National Academy of Sciences of the United States of America. 104: 4676-81. PMID 17360583 DOI: 10.1073/pnas.0700529104  0.572
2007 Ruzicka WB, Zhubi A, Veldic M, Grayson DR, Costa E, Guidotti A. Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection. Molecular Psychiatry. 12: 385-97. PMID 17264840 DOI: 10.1038/Sj.Mp.4001954  0.594
2007 Guidotti A, Ruzicka W, Grayson DR, Veldic M, Pinna G, Davis JM, Costa E. S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis. Neuroreport. 18: 57-60. PMID 17259861 DOI: 10.1097/Wnr.0B013E32800Fefd7  0.616
2007 Kundakovic M, Chen Y, Costa E, Grayson DR. DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes. Molecular Pharmacology. 71: 644-53. PMID 17065238 DOI: 10.1124/Mol.106.030635  0.798
2006 Costa E, Dong E, Grayson DR, Ruzicka WB, Simonini MV, Veldic M, Guidotti A. Epigenetic targets in GABAergic neurons to treat schizophrenia. Advances in Pharmacology (San Diego, Calif.). 54: 95-117. PMID 17175812 DOI: 10.1016/S1054-3589(06)54005-0  0.644
2006 Sharma RP, Rosen C, Kartan S, Guidotti A, Costa E, Grayson DR, Chase K. Valproic acid and chromatin remodeling in schizophrenia and bipolar disorder: preliminary results from a clinical population. Schizophrenia Research. 88: 227-31. PMID 16996718 DOI: 10.1016/J.Schres.2006.07.015  0.598
2006 Grayson DR, Chen Y, Costa E, Dong E, Guidotti A, Kundakovic M, Sharma RP. The human reelin gene: transcription factors (+), repressors (-) and the methylation switch (+/-) in schizophrenia. Pharmacology & Therapeutics. 111: 272-86. PMID 16574235 DOI: 10.1016/J.Pharmthera.2005.01.007  0.796
2006 Pinna G, Agis-Balboa RC, Zhubi A, Matsumoto K, Grayson DR, Costa E, Guidotti A. Imidazenil and diazepam increase locomotor activity in mice exposed to protracted social isolation. Proceedings of the National Academy of Sciences of the United States of America. 103: 4275-80. PMID 16537521 DOI: 10.1073/Pnas.0600329103  0.524
2005 Dong E, Agis-Balboa RC, Simonini MV, Grayson DR, Costa E, Guidotti A. Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 102: 12578-83. PMID 16113080 DOI: 10.1073/Pnas.0505394102  0.671
2005 Sharma RP, Grayson DR, Guidotti A, Costa E. Chromatin, DNA methylation and neuron gene regulation--the purpose of the package. Journal of Psychiatry & Neuroscience : Jpn. 30: 257-63. PMID 16049569  0.574
2005 Grayson DR, Jia X, Chen Y, Sharma RP, Mitchell CP, Guidotti A, Costa E. Reelin promoter hypermethylation in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 102: 9341-6. PMID 15961543 DOI: 10.1073/Pnas.0503736102  0.647
2005 Guidotti A, Auta J, Davis JM, Dong E, Grayson DR, Veldic M, Zhang X, Costa E. GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon. Psychopharmacology. 180: 191-205. PMID 15864560 DOI: 10.1007/S00213-005-2212-8  0.596
2005 Mitchell CP, Chen Y, Kundakovic M, Costa E, Grayson DR. Histone deacetylase inhibitors decrease reelin promoter methylation in vitro. Journal of Neurochemistry. 93: 483-92. PMID 15816871 DOI: 10.1111/J.1471-4159.2005.03040.X  0.76
2005 Tremolizzo L, Doueiri MS, Dong E, Grayson DR, Davis J, Pinna G, Tueting P, Rodriguez-Menendez V, Costa E, Guidotti A. Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice. Biological Psychiatry. 57: 500-9. PMID 15737665 DOI: 10.1016/J.Biopsych.2004.11.046  0.655
2005 Noh JS, Sharma RP, Veldic M, Salvacion AA, Jia X, Chen Y, Costa E, Guidotti A, Grayson DR. DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical cultures. Proceedings of the National Academy of Sciences of the United States of America. 102: 1749-54. PMID 15671176 DOI: 10.1073/Pnas.0409648102  0.647
2005 Mitchell CP, Grayson DR, Goldman MB. Neonatal lesions of the ventral hippocampal formation alter GABA-A receptor subunit mRNA expression in adult rat frontal pole. Biological Psychiatry. 57: 49-55. PMID 15607300 DOI: 10.1016/J.Biopsych.2004.09.017  0.423
2004 Costa E, Davis JM, Dong E, Grayson DR, Guidotti A, Tremolizzo L, Veldic M. A GABAergic cortical deficit dominates schizophrenia pathophysiology. Critical Reviews in Neurobiology. 16: 1-23. PMID 15581395 DOI: 10.1615/Critrevneurobiol.V16.I12.10  0.63
2004 Costa E, Grayson DR, Veldic M, Guidotti A. Neurochemical basis for an epigenetic vision of synaptic organization. International Review of Neurobiology. 59: 73-91. PMID 15006485 DOI: 10.1016/S0074-7742(04)59004-9  0.503
2004 Veldic M, Caruncho HJ, Liu WS, Davis J, Satta R, Grayson DR, Guidotti A, Costa E. DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains. Proceedings of the National Academy of Sciences of the United States of America. 101: 348-53. PMID 14684836 DOI: 10.1073/Pnas.2637013100  0.76
2003 Costa E, Grayson DR, Guidotti A. Epigenetic downregulation of GABAergic function in schizophrenia: potential for pharmacological intervention? Molecular Interventions. 3: 220-9. PMID 14993449 DOI: 10.1124/Mi.3.4.220  0.559
2003 Costa E, Grayson DR, Mitchell CP, Tremolizzo L, Veldic M, Guidotti A. GABAergic cortical neuron chromatin as a putative target to treat schizophrenia vulnerability. Critical Reviews in Neurobiology. 15: 121-42. PMID 14977367 DOI: 10.1615/Critrevneurobiol.V15.I2.20  0.643
2003 Dong E, Caruncho H, Liu WS, Smalheiser NR, Grayson DR, Costa E, Guidotti A. A reelin-integrin receptor interaction regulates Arc mRNA translation in synaptoneurosomes. Proceedings of the National Academy of Sciences of the United States of America. 100: 5479-84. PMID 12707415 DOI: 10.1073/Pnas.1031602100  0.702
2003 Sanna A, Congeddu E, Porcella A, Saba L, Pistis M, Peis M, Marchese G, Ruiu S, Lobina C, Grayson DR, Gessa GL, Pani L. Characterization of wild-type (R100R) and mutated (Q100Q) GABAA alpha 6 subunit in Sardinian alcohol non-preferring rats (sNP). Brain Research. 967: 98-105. PMID 12650970 DOI: 10.1016/S0006-8993(02)04230-0  0.309
2002 Costa E, Chen Y, Davis J, Dong E, Noh JS, Tremolizzo L, Veldic M, Grayson DR, Guidotti A. REELIN and schizophrenia: a disease at the interface of the genome and the epigenome. Molecular Interventions. 2: 47-57. PMID 14993361 DOI: 10.1124/Mi.2.1.47  0.622
2002 Tremolizzo L, Carboni G, Ruzicka WB, Mitchell CP, Sugaya I, Tueting P, Sharma R, Grayson DR, Costa E, Guidotti A. An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability. Proceedings of the National Academy of Sciences of the United States of America. 99: 17095-100. PMID 12481028 DOI: 10.1073/Pnas.262658999  0.641
2002 Liu J, Schmitt KL, Kharlamov EA, Stolarski CJ, Grayson DR, Kelly KM. Quantitative reverse transcription-polymerase chain reaction of GABA(A) alpha1, beta1 and gamma2S subunits in epileptic rats following photothrombotic infarction of neocortex. Epilepsy Research. 52: 85-95. PMID 12458025 DOI: 10.1016/S0920-1211(02)00194-8  0.354
2002 Costa E, Auta J, Grayson DR, Matsumoto K, Pappas GD, Zhang X, Guidotti A. GABAA receptors and benzodiazepines: a role for dendritic resident subunit mRNAs. Neuropharmacology. 43: 925-37. PMID 12423662 DOI: 10.1016/S0028-3908(02)00199-5  0.534
2002 Shumsky JS, Wu Y, Murphy EH, Nissanov J, O'Brien-Jenkins A, Grayson DR. Differential effects of prenatal cocaine exposure on selected subunit mRNAs of the GABA(A) receptor in rabbit anterior cingulate cortex. Journal of Chemical Neuroanatomy. 24: 243-55. PMID 12406500 DOI: 10.1016/S0891-0618(02)00067-4  0.325
2002 Chen Y, Sharma RP, Costa RH, Costa E, Grayson DR. On the epigenetic regulation of the human reelin promoter. Nucleic Acids Research. 30: 2930-9. PMID 12087179 DOI: 10.1093/Nar/Gkf401  0.647
2001 Costa E, Davis J, Grayson DR, Guidotti A, Pappas GD, Pesold C. Dendritic spine hypoplasticity and downregulation of reelin and GABAergic tone in schizophrenia vulnerability. Neurobiology of Disease. 8: 723-42. PMID 11592844 DOI: 10.1006/Nbdi.2001.0436  0.598
2000 Guidotti A, Auta J, Davis JM, Di-Giorgi-Gerevini V, Dwivedi Y, Grayson DR, Impagnatiello F, Pandey G, Pesold C, Sharma R, Uzunov D, Costa E, DiGiorgi Gerevini V. Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study. Archives of General Psychiatry. 57: 1061-9. PMID 11074872 DOI: 10.1001/Archpsyc.57.11.1061  0.625
2000 Lacor PN, Grayson DR, Auta J, Sugaya I, Costa E, Guidotti A. Reelin secretion from glutamatergic neurons in culture is independent from neurotransmitter regulation. Proceedings of the National Academy of Sciences of the United States of America. 97: 3556-61. PMID 10725375 DOI: 10.1073/Pnas.050589597  0.547
2000 Costa E, Pesold C, Auta J, Caruncho H, Davis J, Davidkova G, Dwivedi Y, Grayson D, Rodriguez M, Uzunov D, Guidotti A. 223. Reelin and GAD67 downregulation and psychosis vulnerability Biological Psychiatry. 47: S68. DOI: 10.1016/S0006-3223(00)00487-X  0.675
2000 Grayson DR, Uzunov DP, Chen Y, Siyanova E, Raca G, Sharma RP, Mirkin S, Costa E. 138. Studies of molecular mechanisms regulating reelin gene expression Biological Psychiatry. 47. DOI: 10.1016/S0006-3223(00)00400-5  0.534
1998 Grayson DR, Zhu W, Harris BT, Vicini S, Zheng T. Differentially expressed GABAA-receptor subunits result in structurally and functionally receptor assemblies following excitatory afferent synaptic transmission. Perspectives On Developmental Neurobiology. 5: 193-205. PMID 9777636  0.303
1998 Wang XH, Zhu WJ, Corsi L, Ikonomovic S, Paljug WR, Vicini S, Grayson DR. Chronic dizocilpine (MK-801) reversibly delays GABA(A) receptor maturation in cerebellar granule neurons in vitro. Journal of Neurochemistry. 71: 693-704. PMID 9681460 DOI: 10.1046/J.1471-4159.1998.71020693.X  0.379
1998 Mizukami K, Ikonomovic MD, Grayson DR, Sheffield R, Armstrong DM. Immunohistochemical study of GABAA receptor alpha1 subunit in the hippocampal formation of aged brains with Alzheimer-related neuropathologic changes. Brain Research. 799: 148-55. PMID 9666109 DOI: 10.1016/S0006-8993(98)00437-5  0.305
1998 Mizukami K, Grayson DR, Ikonomovic MD, Sheffield R, Armstrong DM. GABAA receptor beta 2 and beta 3 subunits mRNA in the hippocampal formation of aged human brain with Alzheimer-related neuropathology. Brain Research. Molecular Brain Research. 56: 268-72. PMID 9602147 DOI: 10.1016/S0169-328X(97)00347-1  0.307
1998 Liu J, Brannen KC, Grayson DR, Morrow AL, Devaud LL, Lauder JM. Prenatal exposure to the pesticide dieldrin or the GABA(A) receptor antagonist bicuculline differentially alters expression of GABA(A) receptor subunit mRNAs in fetal rat brainstem. Developmental Neuroscience. 20: 83-92. PMID 9600394 DOI: 10.1159/000017302  0.376
1998 Vicini S, Wang JF, Li JH, Zhu WJ, Wang YH, Luo JH, Wolfe BB, Grayson DR. Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptors. Journal of Neurophysiology. 79: 555-66. PMID 9463421 DOI: 10.1152/Jn.1998.79.2.555  0.308
1997 Ghose S, Wroblewska B, Corsi L, Grayson DR, De Blas AL, Vicini S, Neale JH. N-acetylaspartylglutamate stimulates metabotropic glutamate receptor 3 to regulate expression of the GABA(A) alpha6 subunit in cerebellar granule cells. Journal of Neurochemistry. 69: 2326-35. PMID 9375663 DOI: 10.1046/J.1471-4159.1997.69062326.X  0.373
1997 Mizukami K, Ikonomovic MD, Grayson DR, Rubin RT, Warde D, Sheffield R, Hamilton RL, Davies P, Armstrong DM. Immunohistochemical study of GABA(A) receptor beta2/3 subunits in the hippocampal formation of aged brains with Alzheimer-related neuropathologic changes. Experimental Neurology. 147: 333-45. PMID 9344558 DOI: 10.1006/Exnr.1997.6591  0.311
1997 Liu J, Morrow AL, Devaud LL, Grayson DR, Lauder JM. Regulation of GABA(A) receptor subunit mRNA expression by the pesticide dieldrin in embryonic brainstem cultures: a quantitative, competitive reverse transcription-polymerase chain reaction study. Journal of Neuroscience Research. 49: 645-53. PMID 9302086 DOI: 10.1002/(Sici)1097-4547(19970901)49:5<645::Aid-Jnr15>3.0.Co;2-U  0.419
1997 Ikonomovic S, Kharlamov E, Manev H, Ikonomovic MD, Grayson DR. GABA and NMDA in the prevention of apoptotic-like cell death in vitro. Neurochemistry International. 31: 283-90. PMID 9220461 DOI: 10.1016/S0197-0186(96)00159-3  0.364
1997 Homanics GE, Ferguson C, Quinlan JJ, Daggett J, Snyder K, Lagenaur C, Mi ZP, Wang XH, Grayson DR, Firestone LL. Gene knockout of the alpha6 subunit of the gamma-aminobutyric acid type A receptor: lack of effect on responses to ethanol, pentobarbital, and general anesthetics. Molecular Pharmacology. 51: 588-96. PMID 9106623 DOI: 10.1124/Mol.51.4.588  0.329
1997 Liu J, Morrow AL, Devaud L, Grayson DR, Lauder JM. GABAA receptors mediate trophic effects of GABA on embryonic brainstem monoamine neurons in vitro. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2420-8. PMID 9065503 DOI: 10.1523/Jneurosci.17-07-02420.1997  0.374
1996 Fryer RH, Kaplan DR, Feinstein SC, Radeke MJ, Grayson DR, Kromer LF. Developmental and mature expression of full-length and truncated TrkB receptors in the rat forebrain. The Journal of Comparative Neurology. 374: 21-40. PMID 8891944 DOI: 10.1002/(Sici)1096-9861(19961007)374:1<21::Aid-Cne2>3.0.Co;2-P  0.361
1996 Zheng TM, Caruncho HJ, Zhu WJ, Vicini S, Ikonomovic S, Grayson DR, Costa E. Chronic flumazenil alters GABA(A) receptor subunit mRNA expression, translation product assembly and channel function in neuronal cultures. The Journal of Pharmacology and Experimental Therapeutics. 277: 525-33. PMID 8613963  0.612
1995 Wang YH, Bosy TZ, Yasuda RP, Grayson DR, Vicini S, Pizzorusso T, Wolfe BB. Characterization of NMDA receptor subunit-specific antibodies: distribution of NR2A and NR2B receptor subunits in rat brain and ontogenic profile in the cerebellum. Journal of Neurochemistry. 65: 176-83. PMID 7790859 DOI: 10.1046/J.1471-4159.1995.65010176.X  0.329
1995 Harris BT, Costa E, Grayson DR. Exposure of neuronal cultures to K+ depolarization or to N-methyl-D-aspartate increases the transcription of genes encoding the alpha 1 and alpha 5 GABAA receptor subunits. Brain Research. Molecular Brain Research. 28: 338-42. PMID 7723631 DOI: 10.1016/0169-328X(94)00240-F  0.473
1995 Kharlamov E, Cagnoli CM, Atabay C, Ikonomović S, Grayson DR, Manev H. Opposite effect of protein synthesis inhibitors on potassium deficiency-induced apoptotic cell death in immature and mature neuronal cultures. Journal of Neurochemistry. 65: 1395-8. PMID 7643118 DOI: 10.1046/J.1471-4159.1995.65031395.X  0.318
1994 Zheng TM, Zhu WJ, Puia G, Vicini S, Grayson DR, Costa E, Caruncho HJ. Changes in gamma-aminobutyrate type A receptor subunit mRNAs, translation product expression, and receptor function during neuronal maturation in vitro. Proceedings of the National Academy of Sciences of the United States of America. 91: 10952-6. PMID 7971990 DOI: 10.1073/Pnas.91.23.10952  0.711
1994 Costa E, Cheney DL, Grayson DR, Korneyev A, Longone P, Pani L, Romeo E, Zivkovich E, Guidotti A. Pharmacology of neurosteroid biosynthesis. Role of the mitochondrial DBI receptor (MDR) complex. Annals of the New York Academy of Sciences. 746: 223-42. PMID 7825880  0.403
1993 Lanaud P, Maggio R, Gale K, Grayson DR. Temporal and spatial patterns of expression of c-fos, zif/268, c-jun and jun-B mRNAs in rat brain following seizures evoked focally from the deep prepiriform cortex. Experimental Neurology. 119: 20-31. PMID 8432348 DOI: 10.1006/exnr.1993.1003  0.475
1993 Maggio R, Lanaud P, Grayson DR, Gale K. Expression of c-fos mRNA following seizures evoked from an epileptogenic site in the deep prepiriform cortex: regional distribution in brain as shown by in situ hybridization. Experimental Neurology. 119: 11-9. PMID 8432343 DOI: 10.1006/exnr.1993.1002  0.45
1992 Bovolin P, Santi MR, Memo M, Costa E, Grayson DR. Distinct developmental patterns of expression of rat alpha 1, alpha 5, gamma 2S, and gamma 2L gamma-aminobutyric acidA receptor subunit mRNAs in vivo and in vitro. Journal of Neurochemistry. 59: 62-72. PMID 1319473 DOI: 10.1111/J.1471-4159.1992.Tb08876.X  0.494
1992 Apud JA, Grayson DR, De Erausquin E, Costa E. Pharmacological characterization of regulation of phosphoinositide metabolism by recombinant 5-HT2 receptors of the rat. Neuropharmacology. 31: 1-8. PMID 1311807 DOI: 10.1016/0028-3908(92)90153-G  0.406
1991 Manev H, Caredda S, Grayson DR. Nonselective inhibition by antisense oligonucleotides of cytosine arabinoside action. Neuroreport. 2: 589-92. PMID 1661621 DOI: 10.1097/00001756-199110000-00009  0.334
1989 Costa RH, Grayson DR, Darnell JE. Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes. Molecular and Cellular Biology. 9: 1415-25. PMID 2786140 DOI: 10.1128/Mcb.9.4.1415  0.331
1988 Costa RH, Lai E, Grayson DR, Darnell JE. The cell-specific enhancer of the mouse transthyretin (prealbumin) gene binds a common factor at one site and a liver-specific factor(s) at two other sites. Molecular and Cellular Biology. 8: 81-90. PMID 3336368 DOI: 10.1128/Mcb.8.1.81  0.313
1988 Grayson DR, Costa RH, Xanthopoulos KG, Darnell JE. A cell-specific enhancer of the mouse alpha 1-antitrypsin gene has multiple functional regions and corresponding protein-binding sites. Molecular and Cellular Biology. 8: 1055-66. PMID 2835657 DOI: 10.1128/Mcb.8.3.1055  0.351
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